Glyoxylate metabolism and glycine degradation
|
|
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- AGT1
- AGT2
- AGXT
- AGXT2
- ALDH4
- ALDH4A1
- C10orf65
- DAMOX
- DAO
- DDO
- DHDPSL
- GLXR
- GNMT
- GOT2
- GOX1
- GRHPR
- HAO1
- HOGA1
- HSPOX1
- HYPDH
- KYAT4
- P5CDH
- PMP22
- PRODH2
- PXMP2
- SPAT
|
|
Impaired BRCA2 binding to RAD51
|
|
|
- AGS1
- ATM
- ATR
- ATRIP
- BACH1
- BARD1
- BLM
- BRCA1
- BRCA2
- BRIP1
- C12orf32
- C16orf75
- C7orf76
- C9orf76
- CTIP
- DNA2
- DNA2L
- DSS1
- EXO1
- EXOI
- FACD
- FANCD1
- FANCJ
- FRP1
- HEX1
- HNGS1
- HTATIP
- HUS1
- KAT5
- KIAA0083
- KIAA0259
- MRE11
- MRE11A
- NBN
- NBS
- NBS1
- P95
- R24L
- RAD1
- RAD17
- RAD50
- RAD51
- RAD51A
- RAD9A
- RAD9B
- RBBP8
- REC1
- RECA
- RECQ2
- RECQ3
- RECQL2
- RECQL3
- REPA1
- REPA2
- REPA3
- RFC2
- RFC3
- RFC4
- RFC5
- RHINO
- RHNO1
- RMI1
- RMI2
- RNF53
- RPA1
- RPA14
- RPA2
- RPA3
- RPA32
- RPA34
- RPA70
- SEM1
- SHFDG1
- SHFM1
- TIP60
- TOP3
- TOP3A
- TOPBP1
- WRN
|
|
Presynaptic phase of homologous DNA pairing and strand exchange
|
|
|
- AGS1
- ATM
- ATR
- ATRIP
- BACH1
- BARD1
- BLM
- BRCA1
- BRCA2
- BRIP1
- C12orf32
- C16orf75
- C7orf76
- C9orf76
- CHEK1
- CHK1
- CTIP
- DNA2
- DNA2L
- DSS1
- EXO1
- EXOI
- FACD
- FANCD1
- FANCJ
- FRP1
- HEX1
- HNGS1
- HTATIP
- HUS1
- KAT5
- KIAA0083
- KIAA0259
- MRE11
- MRE11A
- NBN
- NBS
- NBS1
- P95
- R24L
- RAD1
- RAD17
- RAD50
- RAD51
- RAD51A
- RAD51B
- RAD51C
- RAD51D
- RAD51L1
- RAD51L2
- RAD51L3
- RAD9A
- RAD9B
- RBBP8
- REC1
- REC2
- RECA
- RECQ2
- RECQ3
- RECQL2
- RECQL3
- REPA1
- REPA2
- REPA3
- RFC2
- RFC3
- RFC4
- RFC5
- RHINO
- RHNO1
- RMI1
- RMI2
- RNF53
- RPA1
- RPA14
- RPA2
- RPA3
- RPA32
- RPA34
- RPA70
- SEM1
- SHFDG1
- SHFM1
- TIP60
- TOP3
- TOP3A
- TOPBP1
- WRN
- XRCC2
|
|
Activation of ATR in response to replication stress
|
|
|
- AGS1
- ASK
- ATR
- ATRIP
- BM28
- C20orf154
- CCNL1
- CDC18L
- CDC21
- CDC25A
- CDC25C
- CDC45
- CDC45L
- CDC45L2
- CDC46
- CDC47
- CDC6
- CDC7
- CDC7L1
- CDCL1
- CDK2
- CDKN2
- CHEK1
- CHK1
- CLSPN
- DBF4
- DBF4A
- FRP1
- HUS1
- KIAA0030
- LATHEO
- MCM10
- MCM2
- MCM3
- MCM4
- MCM5
- MCM6
- MCM7
- MCM8
- ORC1
- ORC1L
- ORC2
- ORC2L
- ORC3
- ORC3L
- ORC4
- ORC4L
- ORC5
- ORC5L
- ORC6
- ORC6L
- PARC1
- R24L
- RAD1
- RAD17
- RAD9A
- RAD9B
- REC1
- REPA1
- REPA2
- REPA3
- RFC2
- RFC3
- RFC4
- RFC5
- RPA1
- RPA14
- RPA2
- RPA3
- RPA32
- RPA34
- RPA70
- ZDBF1
|
|
Fanconi Anemia Pathway
|
|
|
- AGS1
- APITD1
- ATR
- ATRIP
- BTBD12
- C17orf70
- C19orf40
- C1orf86
- CENPS
- CENPX
- DCLRE1A
- DCLRE1B
- EME1
- EME2
- ERCC1
- ERCC11
- ERCC4
- FAA
- FAAP10
- FAAP100
- FAAP16
- FAAP20
- FAAP24
- FAC
- FACA
- FACC
- FACD
- FACE
- FAN1
- FANCA
- FANCB
- FANCC
- FANCD2
- FANCE
- FANCF
- FANCG
- FANCH
- FANCI
- FANCL
- FANCM
- FRP1
- GIYD1
- GIYD2
- KIAA0086
- KIAA1018
- KIAA1449
- KIAA1596
- KIAA1784
- KIAA1794
- KIAA1987
- MHF1
- MHF2
- MMS4
- MTMR15
- MUS81
- PHF9
- POLN
- REPA1
- REPA2
- REPA3
- RPA1
- RPA14
- RPA2
- RPA3
- RPA32
- RPA34
- RPA70
- RPS27A
- SLX1
- SLX1A
- SLX1B
- SLX4
- SNM1
- SNM1A
- SNM1B
- STRA13
- UAF1
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- UBE2T
- USP1
- WDR48
- XPF
- XRCC9
|
|
Regulation of TP53 Activity through Phosphorylation
|
|
|
- AGS1
- AIK
- AIK2
- AIM1
- AIRK1
- AIRK2
- AMPK
- AMPK1
- AMPK2
- AMPKG3
- ARK1
- ARK2
- ARK5
- ATM
- ATR
- ATRIP
- AURA
- AURKA
- AURKB
- AYK1
- BA2R
- BACH1
- BARD1
- BLM
- BRCA1
- BRIP1
- BTAK
- C12orf32
- C16orf75
- C20orf1
- C20orf2
- C20orf64
- C9orf76
- CCG1
- CCGS
- CCN1
- CCNA
- CCNA1
- CCNA2
- CDK2
- CDK5
- CDK5R
- CDK5R1
- CDKN2
- CDKN5
- CDS1
- CHEK1
- CHEK2
- CHK1
- CHK2
- CIF150
- CK2A1
- CK2A2
- CK2N
- CNK
- CSBP
- CSBP1
- CSBP2
- CSNK2A1
- CSNK2A2
- CSNK2B
- CSPB1
- CTIP
- DIL2
- DNA2
- DNA2L
- DYRK2
- EXO1
- EXOI
- FACT140
- FACT80
- FACTP140
- FANCJ
- FNK
- FRP1
- G5A
- GTF2D1
- HCA519
- HEX1
- HIPK1
- HIPK2
- HNGS1
- HTATIP
- HUS1
- IAK1
- KAT5
- KIAA0083
- KIAA0259
- KIAA0537
- KIAA0630
- LKB1
- MAPK11
- MAPK14
- MAPKAPK5
- MDM2
- MDM4
- MDMX
- MRE11
- MRE11A
- MXI2
- MYAK
- NBAK2
- NBN
- NBS
- NBS1
- NCK5A
- NIR
- NOC2L
- NUAK1
- OMPHK1
- P53
- P53DINP1
- P95
- PIN1
- PJS
- PLK3
- PRAK
- PRK
- PRKAA1
- PRKAA2
- PRKAB1
- PRKAB2
- PRKAG1
- PRKAG2
- PRKAG3
- PRKM11
- PRPK
- PSSALRE
- R24L
- RAD1
- RAD17
- RAD50
- RAD53
- RAD9A
- RAD9B
- RBBP8
- RBP56
- REC1
- RECQ2
- RECQ3
- RECQL2
- RECQL3
- REPA1
- REPA2
- REPA3
- RFC2
- RFC3
- RFC4
- RFC5
- RHINO
- RHNO1
- RMI1
- RMI2
- RNF53
- RPA1
- RPA14
- RPA2
- RPA3
- RPA32
- RPA34
- RPA70
- RPS27A
- SAPK2
- SAPK2A
- SAPK2B
- SIP
- SSRP1
- STK1
- STK11
- STK12
- STK15
- STK5
- STK6
- SUPT16H
- TAF1
- TAF10
- TAF11
- TAF12
- TAF13
- TAF15
- TAF1L
- TAF2
- TAF2A
- TAF2B
- TAF2C
- TAF2C1
- TAF2C2
- TAF2D
- TAF2E
- TAF2F
- TAF2G
- TAF2H
- TAF2I
- TAF2J
- TAF2K
- TAF2N
- TAF2Q
- TAF3
- TAF4
- TAF4A
- TAF4B
- TAF5
- TAF6
- TAF7
- TAF7L
- TAF9
- TAF9B
- TAF9L
- TAFII105
- TAFII130
- TAFII135
- TAFII18
- TAFII20
- TAFII30
- TAFII31
- TAFII55
- TAFII70
- TBP
- TF2D
- TFIID
- TIP60
- TOP3
- TOP3A
- TOPBP1
- TP53
- TP53INP1
- TP53RK
- TPX2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- WRN
|
|
Defective EXT1 causes exostoses 1, TRPS2 and CHDS
|
|
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- AGRIN
- AGRN
- EXT1
- EXT2
- GPC1
- GPC2
- GPC3
- GPC4
- GPC5
- GPC6
- HSPG1
- HSPG2
- KIAA0468
- OCI5
- SDC
- SDC1
- SDC2
- SDC3
- SDC4
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|
Defective EXT2 causes exostoses 2
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|
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- AGRIN
- AGRN
- EXT1
- EXT2
- GPC1
- GPC2
- GPC3
- GPC4
- GPC5
- GPC6
- HSPG1
- HSPG2
- KIAA0468
- OCI5
- SDC
- SDC1
- SDC2
- SDC3
- SDC4
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|
HS-GAG degradation
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- AGRIN
- AGRN
- ELNR1
- GLB1
- GLB1L
- GLB1L2
- GLB1L3
- GPC1
- GPC2
- GPC3
- GPC4
- GPC5
- GPC6
- GUSB
- HEP
- HPA
- HPA1
- HPA2
- HPR1
- HPSE
- HPSE1
- HPSE2
- HSE1
- HSPG1
- HSPG2
- HSS
- IDS
- IDUA
- KIAA0468
- NAGLU
- OCI5
- SDC
- SDC1
- SDC2
- SDC3
- SDC4
- SGSH
- SIDS
- UFHSD1
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Respiratory syncytial virus (RSV) attachment and entry
|
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|
- AGRIN
- AGRN
- CD14
- CMKBRL1
- CX3CR1
- EGFR
- ERBB
- ERBB1
- ESOP1
- F
- FUR
- FURIN
- GPC1
- GPC2
- GPC3
- GPC4
- GPC5
- GPC6
- GPR13
- HER1
- HSPG1
- HSPG2
- IGF1R
- KIAA0468
- L
- LY96
- M
- M2-1
- MD2
- N
- NCL
- OCI5
- P
- PACE
- PCSK3
- RAB5
- RAB5A
- RAB5B
- RAB5C
- RABL
- SDC
- SDC1
- SDC2
- SDC3
- SDC4
- TLR4
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|
Non-integrin membrane-ECM interactions
|
|
|
- AGRIN
- AGRN
- CAK
- DAG1
- DDR1
- DDR2
- DMD
- EDDR1
- FGF2
- FGFB
- HSPG2
- KIAA0533
- KIAA0578
- KIAA1907
- LAMA
- LAMA1
- LAMA2
- LAMA3
- LAMA4
- LAMA5
- LAMB1
- LAMB2
- LAMB2T
- LAMB3
- LAMC1
- LAMC2
- LAMC3
- LAMM
- LAMNA
- LAMNB1
- LAMNB2
- LAMS
- NEP
- NRXN1
- NTN4
- NTRK4
- NTRKR3
- PALB
- PDGF1
- PDGF2
- PDGFA
- PDGFB
- PTK3A
- RTK6
- SIS
- TKT
- TRKE
- TTR
- TYRO10
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|
Integrin cell surface interactions
|
|
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- AGRIN
- AGRN
- BNSP
- BSG
- C21orf43
- CD11A
- CD11B
- CD11C
- CD18
- CD44
- CD47
- CD49B
- CD49D
- CDH1
- CDHE
- COL13A1
- COL16A1
- COL18A1
- COL23A1
- COL4A1
- COL4A2
- COL4A3
- COL4A4
- COL9A1
- COL9A2
- COL9A3
- COMP
- CR3A
- F11R
- FBN
- FBN1
- FGA
- FGB
- FGG
- FLK1
- FN
- FN1
- FNRA
- FNRB
- GP2B
- GP3A
- HSPG2
- HXB
- IBSP
- ICAM1
- ICAM2
- ICAM3
- ICAM4
- ICAM5
- ITGA1
- ITGA10
- ITGA11
- ITGA2
- ITGA2B
- ITGA3
- ITGA4
- ITGA5
- ITGA6
- ITGA7
- ITGA8
- ITGA9
- ITGAB
- ITGAD
- ITGAE
- ITGAL
- ITGAM
- ITGAV
- ITGAX
- ITGB1
- ITGB2
- ITGB3
- ITGB5
- ITGB6
- ITGB7
- ITGB8
- JAM1
- JAM2
- JAM3
- JCAM
- KDR
- LDC
- LHR
- LUM
- LW
- MDF2
- MDU2
- MDU3
- MER6
- MFI7
- MIC4
- MSK12
- MSK18
- MSK8
- OPN
- PECAM1
- SLRR2D
- SPP1
- THBS1
- TLCN
- TLN
- TNC
- TSP
- TSP1
- UVO
- VCAM1
- VEGFR2
- VEJAM
- VNRA
- VTN
- VTNR
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|
Defective B4GALT7 causes EDS, progeroid type
|
|
|
- AGRIN
- AGRN
- B4GALT7
- BCAN
- BEHAB
- BGN
- CALEB
- CSPG2
- CSPG3
- CSPG4
- CSPG5
- CSPG7
- DCN
- GPC1
- GPC2
- GPC3
- GPC4
- GPC5
- GPC6
- HSPG1
- HSPG2
- KIAA0468
- MCSP
- NCAN
- NEUR
- NGC
- OCI5
- SDC
- SDC1
- SDC2
- SDC3
- SDC4
- SLRR1A
- SLRR1B
- VCAN
- XGALT1
|
|
Defective B3GAT3 causes JDSSDHD
|
|
|
- AGRIN
- AGRN
- B3GAT3
- BCAN
- BEHAB
- BGN
- CALEB
- CSPG2
- CSPG3
- CSPG4
- CSPG5
- CSPG7
- DCN
- GPC1
- GPC2
- GPC3
- GPC4
- GPC5
- GPC6
- HSPG1
- HSPG2
- KIAA0468
- MCSP
- NCAN
- NEUR
- NGC
- OCI5
- SDC
- SDC1
- SDC2
- SDC3
- SDC4
- SLRR1A
- SLRR1B
- VCAN
|
|
Defective B3GALT6 causes EDSP2 and SEMDJL1
|
|
|
- AGRIN
- AGRN
- B3GALT6
- BCAN
- BEHAB
- BGN
- CALEB
- CSPG2
- CSPG3
- CSPG4
- CSPG5
- CSPG7
- DCN
- GPC1
- GPC2
- GPC3
- GPC4
- GPC5
- GPC6
- HSPG1
- HSPG2
- KIAA0468
- MCSP
- NCAN
- NEUR
- NGC
- OCI5
- SDC
- SDC1
- SDC2
- SDC3
- SDC4
- SLRR1A
- SLRR1B
- VCAN
|
|
A tetrasaccharide linker sequence is required for GAG synthesis
|
|
|
- AGRIN
- AGRN
- B3GALT6
- B3GAT1
- B3GAT2
- B3GAT3
- B4GALT7
- BCAN
- BEHAB
- BGN
- CALEB
- CSPG2
- CSPG3
- CSPG4
- CSPG5
- CSPG7
- DCN
- GLCATP
- GLCATS
- GPC1
- GPC2
- GPC3
- GPC4
- GPC5
- GPC6
- HSPG1
- HSPG2
- KIAA0468
- KIAA1963
- MCSP
- NCAN
- NEUR
- NGC
- OCI5
- SDC
- SDC1
- SDC2
- SDC3
- SDC4
- SLRR1A
- SLRR1B
- VCAN
- XGALT1
- XT1
- XT2
- XYLT1
- XYLT2
|
|
NCAM1 interactions
|
|
|
- AGRIN
- AGRN
- ALTPRP
- ARTN
- AXT
- CACH1
- CACH2
- CACH3
- CACN1
- CACN2
- CACN4
- CACNA1C
- CACNA1D
- CACNA1G
- CACNA1H
- CACNA1I
- CACNA1S
- CACNB1
- CACNB2
- CACNB3
- CACNB4
- CACNL1A1
- CACNL1A2
- CACNL1A3
- CACNLB1
- CACNLB2
- CACNLB3
- CACNLB4
- CCHL1A1
- CCHL1A2
- CNTN2
- COL29A1
- COL4A1
- COL4A2
- COL4A3
- COL4A4
- COL4A5
- COL6A1
- COL6A2
- COL6A3
- COL6A5
- COL6A6
- COL9A1
- COL9A2
- COL9A3
- CSPG3
- EVN
- GDNF
- GDNFRA
- GDNFRB
- GFRA1
- GFRA2
- GFRA4
- KIAA1120
- KIAA1123
- MYSB
- NCAM
- NCAM1
- NCAN
- NEUR
- NRTN
- PRIP
- PRNP
- PRP
- PSPN
- PST
- PST1
- RETL1
- RETL2
- SIAT8B
- SIAT8D
- ST8SIA2
- ST8SIA4
- STX
- TAG1
- TAX1
- TRNR1
- TRNR2
- VWA4
|
|
Plasmalogen biosynthesis
|
|
|
- AGPS
- DAPAT
- DHAPAT
- DHRS7B
- GNPAT
- SDR32C1
|
|
Acyl chain remodeling of CL
|
|
|
- AGPAT8
- ALCAT1
- CPLA2
- EFE2
- G4.5
- HADH
- HADHA
- HADHB
- LCLAT1
- LYCAT
- PLA2G4
- PLA2G4A
- PLA2G6
- PLPLA9
- TAFAZZIN
- TAZ
|
|
Acyl chain remodelling of PS
|
|
|
- AGPAT7
- AYTL3
- CLEC13C
- CPLA2
- HRASLS3
- HREV107
- KIAA1451
- KIAA1534
- LPCAT3
- LPCAT4
- LPEAT2
- MBOAT1
- MBOAT5
- NMD
- OACT1
- OACT5
- OBPH1
- ORP10
- ORP5
- ORP8
- OSBP10
- OSBP9
- OSBPL10
- OSBPL5
- OSBPL8
- PLA1A
- PLA2
- PLA2A
- PLA2B
- PLA2G10
- PLA2G12
- PLA2G12A
- PLA2G16
- PLA2G1B
- PLA2G2A
- PLA2G2D
- PLA2G2E
- PLA2G2F
- PLA2G4
- PLA2G4A
- PLA2G4B
- PLA2G4D
- PLA2G4E
- PLA2G4F
- PLA2G5
- PLA2L
- PLA2R1
- PLAAT3
- PPLA2
- PSPLA1
- RASF-A
- SPLASH
|
|
Acyl chain remodelling of PG
|
|
|
- AGPAT7
- AYTL2
- AYTL3
- C20orf155
- CLEC13C
- CLS1
- CPLA2
- CRLS1
- FAM34A
- KIAA0205
- LPCAT1
- LPCAT4
- LPEAT2
- LPGAT1
- PFAAP3
- PLA2
- PLA2A
- PLA2B
- PLA2G10
- PLA2G12
- PLA2G12A
- PLA2G1B
- PLA2G2A
- PLA2G2D
- PLA2G2E
- PLA2G2F
- PLA2G3
- PLA2G4
- PLA2G4A
- PLA2G4B
- PLA2G4D
- PLA2G4F
- PLA2G5
- PLA2L
- PLA2R1
- PPLA2
- RASF-A
- SPLASH
|
|
Acyl chain remodelling of PC
|
|
|
- AGPAT11
- AGPAT7
- AYTL1
- AYTL2
- AYTL3
- CLEC13C
- CPLA2
- HRASLS3
- HREV107
- IPLA22
- IPLA2G
- LPCAT1
- LPCAT2
- LPCAT3
- LPCAT4
- LPEAT2
- MBOAT2
- MBOAT5
- OACT2
- OACT5
- PFAAP3
- PLA2
- PLA2A
- PLA2B
- PLA2G10
- PLA2G12
- PLA2G12A
- PLA2G16
- PLA2G1B
- PLA2G2A
- PLA2G2D
- PLA2G2E
- PLA2G2F
- PLA2G3
- PLA2G4
- PLA2G4A
- PLA2G4B
- PLA2G4C
- PLA2G4D
- PLA2G4E
- PLA2G4F
- PLA2G5
- PLA2G6
- PLA2L
- PLA2R1
- PLAAT3
- PLB
- PLB1
- PLBD1
- PLPLA9
- PNPLA8
- PPLA2
- RASF-A
- SPLASH
- TMEM86B
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O-linked glycosylation
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- AGO61
- B3GALNT2
- B3GNT1
- B3GNT6
- B4GAT1
- C3orf39
- DAG1
- EOGTL
- GTDC2
- GYLTL1B
- KIAA0609
- LARGE
- LARGE1
- LARGE2
- MGAT1.2
- POMGNT1
- POMGNT2
- POMK
- POMT1
- POMT2
- SGK196
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M-decay: degradation of maternal mRNAs by maternally stored factors
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- AGO2
- BTG4
- C2orf29
- CAF1
- CALIF
- CCR4
- CCR4B
- CCR4a
- CDC36
- CDC39
- CNOT1
- CNOT10
- CNOT11
- CNOT2
- CNOT3
- CNOT4
- CNOT6
- CNOT6L
- CNOT7
- CNOT8
- CNOT9
- DDX2A
- DDX2B
- DDX48
- DICER
- DICER1
- EIF2C2
- EIF4A
- EIF4A1
- EIF4A2
- EIF4A3
- EIF4B
- EIF4E
- EIF4EL1
- EIF4F
- EIF4G
- EIF4G1
- EIF4GI
- EPABP2
- ERF2
- HERNA
- KIAA0111
- KIAA0691
- KIAA0928
- KIAA1007
- KIAA1194
- KIAA1741
- LENG2
- NOT1
- NOT2
- NOT3
- NOT4
- PAB1
- PABP
- PABP1
- PABPC1
- PABPC2
- PABPN1L
- PABPNL1
- PAIP1
- PC3B
- POP2
- RCD1
- RNF162C
- RQCD1
- TAB182
- TIS11D
- TNKS1BP1
- ZFP36L2
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Oncogene Induced Senescence
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- AGO1
- AGO3
- AGO4
- BHLHB24
- CAGH26
- CDK4
- CDK6
- CDKN2
- CDKN2A
- CDKN2B
- CDKN2C
- CDKN2D
- CDKN6
- DP1
- DP2
- E2F1
- E2F2
- E2F3
- EIF2C1
- EIF2C3
- EIF2C4
- ERF
- ERK1
- ERK2
- ETS1
- ETS2
- EWSR2
- ID
- ID1
- KIAA0075
- KIAA1093
- KIAA1460
- KIAA1567
- KIAA1582
- KIAA1631
- MAPK1
- MAPK3
- MDM2
- MDM4
- MDMX
- MLM
- MOV10
- MTS1
- MTS2
- P53
- PRKM1
- PRKM2
- PRKM3
- RB1
- RBBP3
- RPS27A
- SP1
- TFDP1
- TFDP2
- TNRC6
- TNRC6A
- TNRC6B
- TNRC6C
- TP53
- TSFP1
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
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