Disassembly of the destruction complex and recruitment of AXIN to the membrane
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- AMER1
- APC
- AXIN
- AXIN1
- C2orf31
- CAV
- CAV1
- CK1G2
- CSNK1A1
- CSNK1G2
- CTNNB
- CTNNB1
- DP2.5
- DVL1
- DVL2
- DVL3
- FAM123B
- FRAT1
- FRAT2
- FZD1
- FZD2
- FZD5
- GSK3B
- INT1
- KIAA0044
- KIAA0208
- LR3
- LRP5
- LRP6
- LRP7
- PPP2CA
- PPP2CB
- PPP2R1A
- PPP2R1B
- PPP2R5A
- PPP2R5B
- PPP2R5C
- PPP2R5D
- PPP2R5E
- WNT1
- WNT3A
- WNT8A
- WNT8B
- WNT8D
- WTX
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Nef mediated downregulation of CD28 cell surface expression
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- AP2M1
- CD28
- CLAPM1
- KIAA0109
- nef
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Formation of annular gap junctions
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- AP2M1
- CLAPM1
- CLH17
- CLH22
- CLTA
- CLTB
- CLTC
- CLTCL
- CLTCL1
- CLTCL2
- CLTD
- DAB2
- DNM
- DNM1
- DNM2
- DOC2
- DYN2
- GJA1
- GJAL
- KIAA0034
- KIAA0109
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Gap junction degradation
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- AP2M1
- CLAPM1
- CLH17
- CLH22
- CLTA
- CLTB
- CLTC
- CLTCL
- CLTCL1
- CLTCL2
- CLTD
- DAB2
- DNM
- DNM1
- DNM2
- DOC2
- DYN2
- GJA1
- GJAL
- KIAA0034
- KIAA0109
- KIAA0389
- MYO6
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Trafficking of GluR2-containing AMPA receptors
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- A15
- ADTAA
- AP2A1
- CLAPA1
- DXS1692E
- GLUA1
- GLUH1
- GLUR1
- GLUR2
- GLUR3
- GLUR4
- GLURC
- GRIA1
- GRIA2
- GRIA3
- GRIA4
- GRIP1
- GRIP2
- GluA2
- GluA3
- GluA4
- KIAA1719
- MXS1
- NSF
- PICK1
- PKCA
- PKCB
- PKCG
- PRKACA
- PRKCA
- PRKCABP
- PRKCB
- PRKCB1
- PRKCG
- TM4SF2
- TSPAN7
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Nef Mediated CD8 Down-regulation
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- ADTAA
- ADTAB
- ADTB2
- AP17
- AP2A1
- AP2A2
- AP2B1
- AP2M1
- AP2S1
- ATP6V1H
- CD8B
- CD8B1
- CLAPA1
- CLAPA2
- CLAPB1
- CLAPM1
- CLAPS2
- HIP9
- HYPJ
- KIAA0109
- KIAA0899
- nef
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VLDLR internalisation and degradation
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- ADTAA
- ADTAB
- ADTB2
- AP17
- AP2A1
- AP2A2
- AP2B1
- AP2M1
- AP2S1
- BZF1
- CLAPA1
- CLAPA2
- CLAPB1
- CLAPM1
- CLAPS2
- CLH17
- CLTA
- CLTC
- CLTCL2
- HIP9
- HYPJ
- IDOL
- KIAA0034
- KIAA0109
- KIAA0899
- LXRA
- LXRB
- MYLIP
- NARC1
- NER
- NR1H2
- NR1H3
- PCSK9
- RPS27A
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- UNR
- VLDLR
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WNT5A-dependent internalization of FZD2, FZD5 and ROR2
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- ADTAA
- ADTAB
- ADTB2
- AP17
- AP2A1
- AP2A2
- AP2B1
- AP2M1
- AP2S1
- C2orf31
- CLAPA1
- CLAPA2
- CLAPB1
- CLAPM1
- CLAPS2
- CLH17
- CLTA
- CLTB
- CLTC
- CLTCL2
- FZD2
- FZD5
- HIP9
- HYPJ
- KIAA0034
- KIAA0109
- KIAA0899
- NTRKR1
- NTRKR2
- ROR1
- ROR2
- WNT5A
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Recycling pathway of L1
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- ADTAA
- ADTAB
- ADTB2
- AP17
- AP2A1
- AP2A2
- AP2B1
- AP2M1
- AP2S1
- C14orf41
- CAML1
- CLAPA1
- CLAPA2
- CLAPB1
- CLAPM1
- CLAPS2
- CLH17
- CLTA
- CLTC
- CLTCL2
- CNSA2
- CRMP2
- DNM
- DNM1
- DNM2
- DNM3
- DPYSL2
- DYN2
- ERK2
- EZR
- HIP9
- HYPJ
- ISPK1
- KIAA0034
- KIAA0109
- KIAA0820
- KIAA0899
- KIAA1598
- KIF4
- KIF4A
- KIF4B
- L1CAM
- MAPK1
- MAPKAPK1A
- MAPKAPK1B
- MAPKAPK1C
- MIC5
- MSK1
- MSK2
- MSN
- NUMB
- PRKM1
- PRKM2
- RDX
- RPS6KA1
- RPS6KA2
- RPS6KA3
- RPS6KA4
- RPS6KA5
- RPS6KA6
- RSK1
- RSK2
- RSK3
- RSK4
- SH3D2A
- SH3GL2
- SHTN1
- ULIP2
- VIL2
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Retrograde neurotrophin signalling
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- ADTAA
- ADTAB
- ADTB2
- AP17
- AP2A1
- AP2A2
- AP2B1
- AP2M1
- AP2S1
- CLAPA1
- CLAPA2
- CLAPB1
- CLAPM1
- CLAPS2
- CLH17
- CLTA
- CLTC
- CLTCL2
- CNSA2
- DNAL4
- DNM
- DNM1
- DNM2
- DNM3
- DYN2
- HIP9
- HYPJ
- KIAA0034
- KIAA0109
- KIAA0820
- KIAA0899
- MTC
- NGF
- NGFB
- NTRK1
- SH3D2A
- SH3GL2
- TRK
- TRKA
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WNT5A-dependent internalization of FZD4
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- ADTAA
- ADTAB
- ADTB2
- AP17
- AP2A1
- AP2A2
- AP2B1
- AP2M1
- AP2S1
- ARB2
- ARR2
- ARRB2
- CLAPA1
- CLAPA2
- CLAPB1
- CLAPM1
- CLAPS2
- CLH17
- CLTA
- CLTB
- CLTC
- CLTCL2
- DVL2
- FZD4
- HIP9
- HYPJ
- KIAA0034
- KIAA0109
- KIAA0899
- PKCA
- PKCB
- PKCG
- PRKACA
- PRKCA
- PRKCB
- PRKCB1
- PRKCG
- WNT5A
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LDL clearance
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- AADACL1
- ACACT
- ACACT1
- ACACT2
- ACAT
- ACAT1
- ACAT2
- ADTAA
- ADTAB
- ADTB2
- AP17
- AP2A1
- AP2A2
- AP2B1
- AP2M1
- AP2S1
- APOB
- ARH
- CES3
- CLAPA1
- CLAPA2
- CLAPB1
- CLAPM1
- CLAPS2
- CLH17
- CLTA
- CLTC
- CLTCL2
- HE1
- HIP9
- HYPJ
- ILDR3
- KIAA0034
- KIAA0109
- KIAA0899
- KIAA1363
- LDLR
- LDLRAP1
- LIPA
- LISCH
- LSR
- NARC1
- NCEH1
- NPC1
- NPC2
- PCSK9
- SOAT
- SOAT1
- SOAT2
- STAT
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Cargo recognition for clathrin-mediated endocytosis
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- AAK1
- ABCC7
- ADHR
- ADRB2
- ADRB2R
- ADRBK1
- ADRBK2
- ADTAA
- ADTAB
- ADTB2
- AF1P
- AGFG1
- AGTR1
- AGTR1A
- AGTR1B
- AP17
- AP2A1
- AP2A2
- AP2B1
- AP2M1
- AP2S1
- APOB
- ARB2
- AREG
- AREGB
- ARH
- ARR1
- ARR2
- ARRB1
- ARRB2
- ARVP
- AT2R1
- AT2R1B
- AVP
- AVPR2
- B2AR
- BARK
- BARK1
- BARK2
- BTC
- CALM
- CBL
- CBL2
- CD36L2
- CD3D
- CD3G
- CD4
- CFTR
- CHRM2
- CIN85
- CLAPA1
- CLAPA2
- CLAPB1
- CLAPM1
- CLAPS2
- CLH17
- CLH22
- CLTA
- CLTB
- CLTC
- CLTCL
- CLTCL1
- CLTCL2
- CLTD
- CNSA1
- CNSA2
- CNSA3
- COPS1
- COPS2
- COPS3
- COPS4
- COPS5
- COPS6
- COPS7A
- COPS7B
- COPS8
- CSN1
- CSN2
- CSN3
- CSN4
- CSN5
- CSN6
- CSN7A
- CSN7B
- CSN8
- DA41
- DAB2
- DERP10
- DIR
- DIR3
- DOC2
- DQ1
- DQ2
- DTR
- DTS
- DVL2
- DYT1
- EGF
- EGFR
- EPGN
- EPN1
- EPN2
- EPS15
- EPS15L1
- EPS15R
- ERBB
- ERBB1
- EREG
- FCHO1
- FCHO2
- FZD4
- GLUT8
- GLUTX1
- GPS1
- GRK2
- GRK3
- HBEGF
- HBP
- HEGFL
- HER1
- HGS
- HIP9
- HRB
- HRS
- HVIP
- HYPJ
- IGF2R
- IL7R
- ITSN
- ITSN1
- ITSN2
- JAB1
- KIAA0034
- KIAA0080
- KIAA0109
- KIAA0290
- KIAA0319
- KIAA0656
- KIAA0899
- KIAA1048
- KIAA1065
- KIAA1256
- LDLR
- LDLRAP1
- LIMP2
- LIMPII
- LRP2
- M6PR
- MPR46
- MPRD
- MPRI
- N4BP4
- NECAP1
- NECAP2
- NEDD8
- NK1R
- PICALM
- PLIC1
- PLIC2
- POB1
- RAB
- REPS1
- REPS2
- RIP
- RNF55
- RPS27A
- SALF
- SBLF
- SCARB2
- SDGF
- SGIP1
- SH3D1A
- SH3D1B
- SH3D2A
- SH3D2B
- SH3D2C
- SH3GL1
- SH3GL2
- SH3GL3
- SH3KBP1
- SLC18A3
- SLC2A8
- SNAP91
- STAM
- STAM1
- STAM2
- STN1
- STN2
- STNB
- STON1
- STON2
- SVP65
- SWAP
- SYB2
- SYB3
- SYBL1
- SYT
- SYT1
- SYT11
- SYT2
- SYT8
- SYT9
- T3D
- T3G
- TA
- TAC1R
- TACR1
- TF
- TFRC
- TGFA
- TGN46
- TGN51
- TGOLN2
- TOR1A
- TOR1B
- TORA
- TRIP15
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- UBQLN1
- UBQLN2
- V2R
- VACHT
- VAMP2
- VAMP3
- VAMP4
- VAMP7
- VAMP8
- VP
- WNT5A
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Nef mediated downregulation of MHC class I complex cell surface expression
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- ADTB1
- ADTG
- AP19
- AP1B1
- AP1G1
- AP1M1
- AP1M2
- AP1S1
- AP1S2
- AP1S3
- B2M
- BAM22
- CLAPB2
- CLAPG1
- CLAPS1
- CLTNM
- HLA-A
- HLAA
- KIAA1175
- PACS1
- nef
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Purine salvage
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- ADA
- ADA1
- ADAL
- ADAL1
- ADK
- AMPD1
- AMPD2
- AMPD3
- APRT
- DCK
- DGK
- DGUOK
- GMPR
- GMPR1
- GMPR2
- HPRT
- HPRT1
- NP
- PNP
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alectinib-resistant ALK mutants
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NVP-TAE684-resistant ALK mutants
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lorlatinib-resistant ALK mutants
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crizotinib-resistant ALK mutants
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ASP-3026-resistant ALK mutants
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ceritinib-resistant ALK mutants
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brigatinib-resistant ALK mutants
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MDK and PTN in ALK signaling
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- ALK
- HBNF1
- HTPZP2
- MDK
- MK1
- NEGF1
- NEGF2
- PTN
- PTPRZ
- PTPRZ1
- PTPRZ2
- PTPZ
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ALK mutants bind TKIs
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- ALK
- BCL11A
- BIRC6
- C2orf2
- CLH17
- CLTC
- CLTCL2
- CTIP1
- EIF2AK3
- EMAPL4
- EML4
- EVI9
- FN
- FN1
- HIP1
- KIAA0034
- KIAA1289
- KIAA1809
- NPM
- NPM1
- PEK
- PERK
- PKR1
- PP2CB
- PPM1B
- PRKAR1
- PRKAR1A
- STRN
- TSE1
- ZNF856
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Signaling by LTK
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- ACK1
- ALKAL1
- ALKAL2
- ASH
- FAM150A
- FAM150B
- GRB1
- GRB2
- IRS1
- LTK
- PIK3C1
- PIK3CA
- PIK3CB
- PIK3R1
- PIK3R2
- SOS1
- TNK2
- TYK1
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