Signaling by cytosolic PDGFRA and PDGFRB fusion proteins
|
|
|
- FIP1
- FIP1L1
- KIAA1449
- RHE
- STRN
- UAF1
- WDR48
|
|
Formation of WDR5-containing histone-modifying complexes
|
|
|
- ADA3
- AIB3
- AKAP8L
- ALL1
- ALR
- ASH2L
- ASH2L1
- BIG3
- BOD1
- BOD1L
- BOD1L1
- C12orf41
- C16orf53
- C20orf104
- C20orf13
- CCDC101
- CENP-36
- CFP1
- CGBP
- CSRP2BP
- CXXC1
- CXXC7
- DFS70
- DPY30
- DR1
- FAM44A
- FAM44B
- GCN5
- GCN5L2
- GLEA2
- HALR
- HCA58
- HCF1
- HCFC1
- HCFC2
- HFC1
- HRX
- HRX2
- HTRX
- INO80Q
- KANSL1
- KANSL2
- KANSL3
- KAT14
- KAT2A
- KAT2B
- KAT8
- KDM6A
- KIAA0181
- KIAA0304
- KIAA0339
- KIAA1076
- KIAA1197
- KIAA1267
- KIAA1310
- KIAA1327
- KIAA1506
- KMT2A
- KMT2B
- KMT2C
- KMT2D
- KMT2F
- KMT2G
- LEDGF
- MBIP
- MCRS1
- MEN1
- MLL
- MLL1
- MLL2
- MLL3
- MLL4
- MOF
- MSL1V1
- MSP58
- MYST1
- NAKAP
- NAKAP95
- NCOA6
- NSL1
- NSL2
- NSL3
- NZF
- OGT
- PA1
- PAGR1
- PAXIP1
- PAXIP1L
- PCAF
- PCCX1
- PHF18
- PHF20
- PHF20L1
- PRTD
- PSIP1
- PSIP2
- PTIP
- RAP250
- RBBP5
- RBQ3
- SCG2
- SET1
- SET1A
- SET1B
- SETD1A
- SETD1B
- SGF29
- SI1
- SWD2
- TADA2A
- TADA2L
- TADA3
- TADA3L
- TASP1
- TMEM113
- TRBP
- TRX1
- TRX2
- TZP
- UTX
- WBP7
- WDR5
- WDR82
- WDR82A
- YEATS2
- ZZZ3
|
|
RNA Pol II CTD phosphorylation and interaction with CE
|
- CDK-activating kinase assembly factor MAT1
- Cyclin-H
- Cyclin-dependent kinase 7
- DNA-directed RNA polymerase II subunit RPB11-a
- DNA-directed RNA polymerase II subunit RPB1
- DNA-directed RNA polymerase II subunit RPB2
- DNA-directed RNA polymerase II subunit RPB3
- DNA-directed RNA polymerase II subunit RPB4
- DNA-directed RNA polymerase II subunit RPB7
- DNA-directed RNA polymerase II subunit RPB9
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- General transcription and DNA repair factor IIH helicase subunit XPD
- General transcription and DNA repair factor IIH helicase/translocase subunit XPB
- General transcription factor IIF subunit 1
- General transcription factor IIF subunit 2
- General transcription factor IIH subunit 1
- General transcription factor IIH subunit 2
- General transcription factor IIH subunit 3
- General transcription factor IIH subunit 4
- General transcription factor IIH subunit 5
- Transcription elongation factor SPT5
- mRNA cap guanine-N7 methyltransferase
- mRNA-capping enzyme
|
|
- BTF2
- BTF2P44
- C6orf175
- CAK
- CAK1
- CAP1A
- CAP35
- CCNH
- CDK7
- CDKN7
- ERCC2
- ERCC3
- GTF2F1
- GTF2F2
- GTF2H1
- GTF2H2
- GTF2H3
- GTF2H4
- GTF2H5
- KIAA0398
- MAT1
- MNAT1
- MO15
- POLR2
- POLR2A
- POLR2B
- POLR2C
- POLR2D
- POLR2E
- POLR2F
- POLR2G
- POLR2H
- POLR2I
- POLR2J
- POLR2J1
- POLR2K
- POLR2L
- POLRF
- RAP30
- RAP74
- RNF66
- RNGTT
- RNMT
- RPB7
- SPT5
- SPT5H
- STK1
- SUPT5H
- TTDA
- XPB
- XPBC
- XPD
- XPDC
|
|
GPER1 signaling
|
|
|
- ADCY1
- ADCY2
- ADCY3
- ADCY4
- ADCY5
- ADCY6
- ADCY7
- ADCY8
- ADCY9
- CEPR
- CMKRL2
- DRY12
- FNRA
- FNRB
- GNAI1
- GNAI2
- GNAI2B
- GNAI3
- GNAS
- GNAS1
- GNAT3
- GNAZ
- GNB1
- GNB2
- GNB3
- GNB4
- GNB5
- GNG10
- GNG11
- GNG12
- GNG13
- GNG2
- GNG3
- GNG4
- GNG5
- GNG7
- GNG8
- GNG9
- GNGT1
- GNGT10
- GNGT11
- GNGT2
- GNGT3
- GNGT4
- GNGT5
- GNGT7
- GNGT8
- GNGT9
- GPER
- GPER1
- GPR30
- GSP
- ITGA5
- ITGB1
- KIAA0037
- KIAA0422
- KIAA0511
- KIAA0520
- KIAA1060
- MDF2
- MSK12
- PKACA
- PKR1
- PKR2
- PRKACA
- PRKACB
- PRKACG
- PRKAR1
- PRKAR1A
- PRKAR1B
- PRKAR2
- PRKAR2A
- PRKAR2B
- SRC
- SRC1
- TSE1
|
|
Defective SLC17A5 causes Salla disease (SD) and ISSD
|
|
|
|
|
Interleukin-33 signaling
|
|
|
- C9orf26
- DER4
- IL1F11
- IL1RL1
- IL33
- NFHEV
- ST2
- T1
|
|
Meiotic recombination
|
|
|
- APOLO1
- ATM
- BLM
- BRCA1
- BRCA2
- C1orf112
- CDK2
- CDK4
- CDKN2
- COCA2
- CTIP
- DMC1
- DMC1H
- FACD
- FANCD1
- FIGNL1
- FIRRM
- GAJ
- H2AB1
- H2AC14
- H2AC18
- H2AC19
- H2AC20
- H2AC4
- H2AC6
- H2AC7
- H2AC8
- H2AFA
- H2AFB1
- H2AFE
- H2AFG
- H2AFJ
- H2AFL
- H2AFM
- H2AFO
- H2AFQ
- H2AFV
- H2AFX
- H2AJ
- H2AV
- H2AX
- H2AZ2
- H2BC1
- H2BC10
- H2BC11
- H2BC12
- H2BC12L
- H2BC13
- H2BC14
- H2BC15
- H2BC17
- H2BC21
- H2BC26
- H2BC3
- H2BC4
- H2BC5
- H2BC6
- H2BC7
- H2BC8
- H2BC9
- H2BFA
- H2BFB
- H2BFC
- H2BFD
- H2BFE
- H2BFF
- H2BFG
- H2BFH
- H2BFJ
- H2BFK
- H2BFL
- H2BFN
- H2BFQ
- H2BFR
- H2BFS
- H2BFT
- H2BS1
- H2BU1
- H3-3A
- H3-3B
- H3-4
- H3.3A
- H3.3B
- H3C1
- H3C10
- H3C11
- H3C12
- H3C13
- H3C14
- H3C15
- H3C2
- H3C3
- H3C4
- H3C6
- H3C7
- H3C8
- H3F2
- H3F3
- H3F3A
- H3F3B
- H3FA
- H3FB
- H3FC HIST1H3C
- H3FD
- H3FF
- H3FH
- H3FI
- H3FJ
- H3FK
- H3FL
- H3FM
- H3FT
- H4-16
- H4/A
- H4/B
- H4/C
- H4/D
- H4/E
- H4/G
- H4/H
- H4/I
- H4/J
- H4/K
- H4/M
- H4/N
- H4/O
- H4C1
- H4C11
- H4C12
- H4C13
- H4C14
- H4C15
- H4C16
- H4C2
- H4C3
- H4C4
- H4C5
- H4C6
- H4C8
- H4C9
- H4F2
- H4FA
- H4FB
- H4FC
- H4FD
- H4FE
- H4FG
- H4FH
- H4FI
- H4FJ
- H4FK
- H4FM
- H4FN
- H4FO
- HIRIP1
- HIRIP2
- HIST1H2AB
- HIST1H2AC
- HIST1H2AD
- HIST1H2AE
- HIST1H2AJ
- HIST1H2BA
- HIST1H2BB
- HIST1H2BC
- HIST1H2BD
- HIST1H2BE
- HIST1H2BF
- HIST1H2BG
- HIST1H2BH
- HIST1H2BI
- HIST1H2BJ
- HIST1H2BK
- HIST1H2BL
- HIST1H2BM
- HIST1H2BN
- HIST1H2BO
- HIST1H3A
- HIST1H3B
- HIST1H3D
- HIST1H3E
- HIST1H3F
- HIST1H3G
- HIST1H3H
- HIST1H3I
- HIST1H3J
- HIST1H4A
- HIST1H4B
- HIST1H4C
- HIST1H4D
- HIST1H4E
- HIST1H4F
- HIST1H4H
- HIST1H4I
- HIST1H4J
- HIST1H4K
- HIST1H4L
- HIST2H2AA
- HIST2H2AA3
- HIST2H2AA4
- HIST2H2AC
- HIST2H2BE
- HIST2H3A
- HIST2H3C
- HIST2H3D
- HIST2H4
- HIST2H4A
- HIST2H4B
- HIST3H2BB
- HIST3H3
- HIST4H4
- HNGS1
- HOP2
- LIM15
- MLH1
- MLH3
- MND1
- MRE11
- MRE11A
- MSH4
- MSH5
- NBN
- NBS
- NBS1
- P95
- PFM6
- PRDM9
- PSMC3IP
- RAD50
- RAD51
- RAD51A
- RAD51C
- RAD51L2
- RBBP8
- RECA
- RECQ2
- RECQL3
- REPA1
- REPA2
- REPA3
- RNF53
- RPA1
- RPA14
- RPA2
- RPA3
- RPA32
- RPA34
- RPA70
- SPO11
- TBPIP
- TEX15
- TOP3
- TOP3A
- TSH2B
|
|
Thyroxine biosynthesis
|
|
|
- C6orf71
- CGA
- DEHAL1
- DUOX
- DUOX1
- DUOX2
- IYD
- LNOX1
- LNOX2
- NIS
- SLC5A5
- THOX1
- THOX2
- TPO
- TSHB
|
|
Interaction between L1 and Ankyrins
|
|
|
- ANK
- ANK1
- ANK2
- ANK3
- ANKB
- BSPECV
- CAML1
- HBA
- HUBSPECV
- HUSPECV
- KCNQ2
- KCNQ3
- KIAA0302
- KIAA0343
- KIAA0756
- KIAA1158
- KIAA1356
- KIAA1642
- L1CAM
- MED
- MIC5
- NAC1
- NAC2
- NAC3
- NEAS
- NENA
- NFASC
- NRCAM
- SCA5
- SCN1
- SCN10A
- SCN11A
- SCN12A
- SCN1A
- SCN1B
- SCN2A
- SCN2A1
- SCN2A2
- SCN2B
- SCN3A
- SCN3B
- SCN4A
- SCN4B
- SCN5A
- SCN6A
- SCN7A
- SCN8A
- SCN9A
- SNS2
- SPTA
- SPTA1
- SPTA2
- SPTAN1
- SPTB
- SPTB1
- SPTB2
- SPTBN1
- SPTBN2
- SPTBN3
- SPTBN4
- SPTBN5
|
|
Defective SLC5A2 causes renal glucosuria (GLYS1)
|
|
|
|
|
Downregulation of ERBB4 signaling
|
|
|
- ITCH
- KIAA0093
- NEDD4
- NEDD4-1
- RPF1
- RPS27A
- SRC
- SRC1
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- WWP1
|
|
Signaling by Activin
|
|
|
- ACVR1B
- ACVR1C
- ACVR2
- ACVR2A
- ACVR2B
- ACVRLK4
- ALK4
- ALK7
- DPC4
- DRAP1
- ERK1
- ERK2
- FAST1
- FAST2
- FOXH1
- INHA
- INHBA
- INHBB
- MADH2
- MADH3
- MADH4
- MADR2
- MAPK1
- MAPK3
- PRKM1
- PRKM2
- PRKM3
- SMAD2
- SMAD3
- SMAD4
- TGFBR3
|
|
MyD88-independent TLR4 cascade
|
|
|
- CD14
- ESOP1
- LY96
- MD2
- PRVTIRB
- TICAM1
- TICAM2
- TIRAP3
- TIRP
- TLR4
- TRAM
- TRIF
|
|
Constitutive Signaling by Overexpressed ERBB2
|
|
|
- CDC37
- CDC37A
- ERBB2
- ERBB2IP
- ERBIN
- HER2
- HRAS
- HRAS1
- HSP90A
- HSP90AA1
- HSPC1
- HSPCA
- KIAA1225
- LAP2
- MLN19
- NEU
- NGL
- NRAS
- PTPN12
- SHC
- SHC1
- SHCA
- SOS1
|
|
NTRK2 activates RAC1
|
|
|
- BDNF
- DOCK3
- KIAA0299
- MOCA
- NTRK2
- RAC1
- TC25
- TRKB
|
|
HDMs demethylate histones
|
|
|
- AOF1
- AOF2
- ARID5B
- C5orf7
- C6orf193
- CENP-35
- CXXC2
- CXXC8
- DESRT
- DXS1272E
- FBL10
- FBL11
- FBL7
- FBXL10
- FBXL11
- GASC1
- H3C1
- H3C10
- H3C11
- H3C12
- H3C13
- H3C14
- H3C15
- H3C2
- H3C3
- H3C4
- H3C6
- H3C7
- H3C8
- H3F2
- H3FA
- H3FB
- H3FC HIST1H3C
- H3FD
- H3FF
- H3FH
- H3FI
- H3FJ
- H3FK
- H3FL
- H3FM
- H4-16
- H4/A
- H4/B
- H4/C
- H4/D
- H4/E
- H4/G
- H4/H
- H4/I
- H4/J
- H4/K
- H4/M
- H4/N
- H4/O
- H4C1
- H4C11
- H4C12
- H4C13
- H4C14
- H4C15
- H4C16
- H4C2
- H4C3
- H4C4
- H4C5
- H4C6
- H4C8
- H4C9
- H4F2
- H4FA
- H4FB
- H4FC
- H4FD
- H4FE
- H4FG
- H4FH
- H4FI
- H4FJ
- H4FK
- H4FM
- H4FN
- H4FO
- HIST1H3A
- HIST1H3B
- HIST1H3D
- HIST1H3E
- HIST1H3F
- HIST1H3G
- HIST1H3H
- HIST1H3I
- HIST1H3J
- HIST1H4A
- HIST1H4B
- HIST1H4C
- HIST1H4D
- HIST1H4E
- HIST1H4F
- HIST1H4H
- HIST1H4I
- HIST1H4J
- HIST1H4K
- HIST1H4L
- HIST2H3A
- HIST2H3C
- HIST2H3D
- HIST2H4
- HIST2H4A
- HIST2H4B
- HIST4H4
- HY
- HYA
- JARID1A
- JARID1B
- JARID1C
- JARID1D
- JHDM1A
- JHDM1B
- JHDM1D
- JHDM2A
- JHDM2B
- JHDM3A
- JHDM3B
- JHDM3C
- JHDM3D
- JMJD1
- JMJD1A
- JMJD1B
- JMJD2
- JMJD2A
- JMJD2B
- JMJD2C
- JMJD2D
- JMJD3
- JMJD6
- KDM1
- KDM1A
- KDM1B
- KDM2A
- KDM2B
- KDM3A
- KDM3B
- KDM4A
- KDM4B
- KDM4C
- KDM4D
- KDM5A
- KDM5B
- KDM5C
- KDM5D
- KDM6A
- KDM6B
- KDM6C
- KDM7
- KDM7A
- KIAA0234
- KIAA0346
- KIAA0585
- KIAA0601
- KIAA0662
- KIAA0677
- KIAA0742
- KIAA0780
- KIAA0876
- KIAA1004
- KIAA1082
- KIAA1111
- KIAA1718
- LSD1
- LSD2
- MDIG
- MINA
- MINA53
- MRF2
- NDY1
- NO52
- PCCX2
- PHF2
- PHF8
- PLU1
- PSR
- PTDSR
- RBBP2
- RBBP2H1
- RBP2
- RIOX2
- SMCX
- SMCY
- TSGA
- UTX
- UTY
- XE169
- ZNF422
|
|
LXRs regulate gene expression to limit cholesterol uptake
|
|
|
- BZF1
- IDOL
- LXRA
- LXRB
- MYLIP
- NER
- NR1H2
- NR1H3
- NR2B1
- NR2B2
- RXRA
- RXRB
- UNR
|
|
Zinc influx into cells by the SLC39 gene family
|
|
|
- BIGM103
- HKE4
- IRT1
- KIAA0062
- KIAA1265
- LIV1
- RING5
- SLC39A1
- SLC39A10
- SLC39A14
- SLC39A2
- SLC39A3
- SLC39A4
- SLC39A5
- SLC39A6
- SLC39A7
- SLC39A8
- ZIP1
- ZIP10
- ZIP14
- ZIP2
- ZIP3
- ZIP4
- ZIP5
- ZIP6
- ZIP8
- ZIRTL
|
|
Glucocorticoid biosynthesis
|
|
|
- 3BH
- CBG
- CYP11B1
- CYP11B2
- CYP17
- CYP17A1
- CYP21
- CYP21A2
- CYP21B
- HSD11
- HSD11B1
- HSD11B2
- HSD11K
- HSD11L
- HSD3B1
- HSD3B2
- HSDB3A
- HSDB3B
- POMC
- S11BH
- S17AH
- SDR26C1
- SDR9C3
- SERPINA6
|
|
Toll Like Receptor TLR1:TLR2 Cascade
|
|
|
- CD14
- KIAA0012
- TIL4
- TLR1
- TLR2
- porB
|
|
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
|
|
|
- CYP1A1
- CYP1A2
- CYP1B1
- CYP2C10
- CYP2C19
- CYP2C8
- CYP2C9
- CYP2J2
- EPHX2
|
|
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations
|
|
|
- ATRX
- BING2
- DAP6
- DAXX
- RAD54L
- XH2
|
|
SCF(Skp2)-mediated degradation of p27/p21
|
|
|
- ADRM1
- BCL1
- BRK
- C7orf76
- CAP20
- CCN1
- CCNA
- CCNA1
- CCNA2
- CCND1
- CCNE
- CCNE1
- CCNE2
- CDK2
- CDK4
- CDKN1
- CDKN1A
- CDKN1B
- CDKN2
- CIP1
- CKS1
- CKS1B
- CUL1
- DSS1
- EMC19
- FBXL1
- GP110
- HC2
- HC3
- HC8
- HC9
- HSPC
- KIAA0107
- KIP1
- LMPX
- LMPY
- MB1
- MDA6
- MIP224
- MOV34L
- MSS1
- NU
- OCP2
- PFAAP4
- PIC1
- POH1
- PRAD1
- PROS26
- PROS27
- PROS30
- PSC2
- PSC3
- PSC5
- PSC8
- PSC9
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMB1
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB6
- PSMB7
- PSMC1
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD6
- PSMD7
- PSMD8
- PTK6
- RPS27A
- SDI1
- SEM1
- SHFDG1
- SHFM1
- SKP1
- SKP1A
- SKP2
- SUG1
- SUG2
- TBP1
- TBP7
- TCEB1L
- TRAP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- WAF1
- X
- Y
- Z
- p27
|
|
GRB2 events in EGFR signaling
|
|
|
- AREG
- AREGB
- BTC
- DTR
- DTS
- EGF
- EGFR
- EPGN
- ERBB
- ERBB1
- EREG
- HBEGF
- HEGFL
- HER1
- HRAS
- HRAS1
- NRAS
- SDGF
- SOS1
- TGFA
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Triglyceride biosynthesis
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- AGMO
- AGRP1
- DC2
- DC5
- DC7
- DGAT
- DGAT1
- DGAT2
- DGAT2L1
- DGAT2L5
- DGAT2L7
- GK
- GK2
- GK3
- GK3P
- GKP2
- GKP3
- GKTA
- GKTB
- GPAM
- GPAT1
- GPAT2
- KIAA0188
- KIAA0249
- KIAA1560
- LIPN3L
- LPIN1
- LPIN2
- LPIN3
- MOGAT1
- MOGAT2
- MOGAT3
- TMEM195
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