GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **526 - 550** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
CDC42 GTPase cycle	ADP-ribosylation factor GTPase-activating protein 2 ADP-ribosylation factor GTPase-activating protein 3 ARF GTPase-activating protein GIT1 ARF GTPase-activating protein GIT2 Actin nucleation-promoting factor WAS Actin nucleation-promoting factor WASL Active breakpoint cluster region-related protein Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 BAR/IMD domain-containing adapter protein 2 BTB/POZ domain-containing protein KCTD3 Breakpoint cluster region protein CDC42 small effector protein 2 Caveolin-1 Cdc42 effector protein 1 Cdc42 effector protein 2 Cdc42 effector protein 3 Cdc42 effector protein 4 Cdc42 effector protein 5 Cell division control protein 42 homolog Copine-8 DEP domain-containing protein 1B Dedicator of cytokinesis protein 10 Dedicator of cytokinesis protein 11 Dedicator of cytokinesis protein 6 Dedicator of cytokinesis protein 7 Dedicator of cytokinesis protein 8 Dedicator of cytokinesis protein 9 Delta(14)-sterol reductase LBR Differentially expressed in FDCP 6 homolog Disheveled-associated activator of morphogenesis 1 Dynamin-binding protein Ephexin-1 FERM, ARHGEF and pleckstrin domain-containing protein 1 FYVE, RhoGEF and PH domain-containing protein 1 FYVE, RhoGEF and PH domain-containing protein 2 FYVE, RhoGEF and PH domain-containing protein 3 FYVE, RhoGEF and PH domain-containing protein 4 Formin-binding protein 1-like Formin-binding protein 1 Formin-like protein 1 Formin-like protein 2 Formin-like protein 3 GEM-interacting protein Golgin subfamily A member 8R Guanine nucleotide exchange factor DBS Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Guanine nucleotide-binding protein subunit alpha-13 Inactive Rho GTPase-activating protein 11B Intersectin-1 Junction plakoglobin Kinectin Lamina-associated polypeptide 2, isoforms beta/gamma Metalloreductase STEAP3 Mitogen-activated protein kinase kinase kinase 11 N-chimaerin Oligophrenin-1 Partitioning defective 6 homolog alpha Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phospholipase D1 Pleckstrin homology domain-containing family G member 1 Pleckstrin homology domain-containing family G member 2 Pleckstrin homology domain-containing family G member 3 Pleckstrin homology domain-containing family G member 4B Protein ECT2 Protein FAM13B Protein diaphanous homolog 3 Protein scribble homolog Proto-oncogene DBL Puratrophin-1 Rac GTPase-activating protein 1 Ragulator complex protein LAMTOR1 RalA-binding protein 1 Ras GTPase-activating-like protein IQGAP1 Ras GTPase-activating-like protein IQGAP2 Ras GTPase-activating-like protein IQGAP3 Ras-related protein Rab-7a Ras-specific guanine nucleotide-releasing factor 2 Rho GDP-dissociation inhibitor 1 Rho GDP-dissociation inhibitor 2 Rho GDP-dissociation inhibitor 3 Rho GTPase-activating protein 10 Rho GTPase-activating protein 17 Rho GTPase-activating protein 1 Rho GTPase-activating protein 20 Rho GTPase-activating protein 21 Rho GTPase-activating protein 22 Rho GTPase-activating protein 24 Rho GTPase-activating protein 26 Rho GTPase-activating protein 27 Rho GTPase-activating protein 29 Rho GTPase-activating protein 30 Rho GTPase-activating protein 31 Rho GTPase-activating protein 32 Rho GTPase-activating protein 33 Rho GTPase-activating protein 35 Rho GTPase-activating protein 39 Rho GTPase-activating protein 40 Rho GTPase-activating protein 42 Rho GTPase-activating protein 44 Rho GTPase-activating protein 45 Rho GTPase-activating protein 4 Rho GTPase-activating protein 5 Rho GTPase-activating protein 7 Rho GTPase-activating protein 9 Rho GTPase-activating protein SYDE1 Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 16 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 26 Rho guanine nucleotide exchange factor 4 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 6 Rho guanine nucleotide exchange factor 7 Rho guanine nucleotide exchange factor 9 Rho guanine nucleotide exchange factor TIAM1 SH3 and PX domain-containing protein 2A SH3KBP1-binding protein 1 SLIT-ROBO Rho GTPase-activating protein 1 SLIT-ROBO Rho GTPase-activating protein 2 SLIT-ROBO Rho GTPase-activating protein 3 Serine/threonine-protein kinase MRCK alpha Serine/threonine-protein kinase MRCK beta Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Serine/threonine-protein kinase PAK 4 Serine/threonine-protein kinase PAK 5 Serine/threonine-protein kinase PAK 6 Spermatogenesis-associated protein 13 StAR-related lipid transfer protein 13 StAR-related lipid transfer protein 8 Stomatin Synaptobrevin homolog YKT6 Synaptosomal-associated protein 23 T-cell activation Rho GTPase-activating protein Transferrin receptor protein 1 Triple functional domain protein Unconventional myosin-IXb Vang-like protein 1 Vesicle-associated membrane protein 3 WAS/WASL-interacting protein family member 1 WAS/WASL-interacting protein family member 2 WAS/WASL-interacting protein family member 3 WD repeat-containing protein 81 WD repeat-containing protein 91	A1A4S6 A1L390 A4D1P6 A6NGB9 A6NI28 A7KAX9 I6L899 O00161 O00401 O00459 O14559 O14613 O14827 O15013 O15068 O15085 O15498 O43295 O43307 O43516 O60890 O75044 O75914 O75962 O94989 O95466 O96013 P02786 P10911 P11274 P14923 P15882 P27105 P27986 P42167 P42768 P46940 P51149 P52565 P52566 P52735 P60953 P98171 P98174 Q00587 Q03135 Q07960 Q12774 Q12979 Q13009 Q13017 Q13153 Q13177 Q13393 Q13459 Q13576 Q14155 Q14160 Q14161 Q14344 Q14739 Q15052 Q15311 Q15811 Q15836 Q16584 Q17R89 Q2M1Z3 Q3KRB8 Q52LW3 Q562E7 Q58EX7 Q5JSL3 Q5JSP0 Q5T0N5 Q5T5U3 Q5TCZ1 Q5TG30 Q5VT25 Q5VV41 Q658P3 Q68EM7 Q6IAA8 Q6NZY7 Q6XZF7 Q6ZUM4 Q6ZW31 Q70Z35 Q7Z5H3 Q7Z6B7 Q7Z6I6 Q7Z6J4 Q86UP2 Q86VI3 Q86VW2 Q86YQ8 Q8IVF7 Q8IW93 Q8N103 Q8N264 Q8N5V2 Q8N6H7 Q8NF50 Q8TAA9 Q8TBC3 Q8TCU6 Q8TF74 Q8WUY9 Q8WWN8 Q8WZ64 Q92502 Q92619 Q96BY6 Q96DR7 Q96HP0 Q96M96 Q96N67 Q96N96 Q96P48 Q96PX9 Q96PY5 Q96QB1 Q96RU3 Q99819 Q9BRR9 Q9BZ29 Q9C0H5 Q9H0H5 Q9H3Q1 Q9H4E7 Q9H7P9 Q9H8V3 Q9NP61 Q9NPB6 Q9NQU5 Q9NR80 Q9NRR3 Q9NRY4 Q9NSV4 Q9NYF5 Q9NZN5 Q9P107 Q9P286 Q9P2F6 Q9UKI2 Q9UKW4 Q9ULL1 Q9UNA1 Q9UQB8 Q9Y2X7 Q9Y3M8 Q9Y4D1 Q9Y4F1 Q9Y597 Q9Y5S2	ABR ARAP1 ARAP2 ARAP3 ARFGAP1 ARFGAP2 ARFGAP3 ARHDH9 ARHGAP1 ARHGAP10 ARHGAP11B ARHGAP13 ARHGAP14 ARHGAP17 ARHGAP2 ARHGAP20 ARHGAP21 ARHGAP22 ARHGAP24 ARHGAP26 ARHGAP27 ARHGAP29 ARHGAP30 ARHGAP31 ARHGAP32 ARHGAP33 ARHGAP34 ARHGAP35 ARHGAP39 ARHGAP4 ARHGAP40 ARHGAP42 ARHGAP44 ARHGAP45 ARHGAP5 ARHGAP7 ARHGAP9 ARHGDIA ARHGDIB ARHGDIG ARHGEF10 ARHGEF11 ARHGEF12 ARHGEF15 ARHGEF16 ARHGEF19 ARHGEF25 ARHGEF26 ARHGEF36 ARHGEF4 ARHGEF5 ARHGEF6 ARHGEF7 ARHGEF9 BAIAP2 BCR BCR1 BND7 BORG1 BORG2 BORG3 BORG4 BORG5 C11orf59 C17orf1 C17orf1B C1orf39 C20orf95 C5orf5 CAMGAP1 CAV CAV1 CDC42 CDC42BPA CDC42BPB CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 CDC42EP5 CDC42GAP CDC42SE2 CDEP CDGAP CENTD1 CENTD2 CENTD3 CEP1 CEP2 CEP3 CEP4 CEP5 CG1 CHN CHN1 COOL1 COOL2 CPNE8 CR16 CRIB1 CTNNG D22S11 DAAM1 DBL DEF6 DEPDC1B DEPDC2 DIAP3 DIAPH3 DLC1 DLC2 DLC3 DNMBP DOCK10 DOCK11 DOCK6 DOCK7 DOCK8 DOCK9 DP3 ECT2 EPB72 EPHEXIN4 FAM13B FAM13B1 FAM7B1 FARP1 FBP17 FGD1 FGD2 FGD3 FGD4 FGDY FHOD2 FHOD3 FILGAP FISH FMNL FMNL1 FMNL2 FMNL3 FNBP1 FNBP1L FNBP2 FRABP FRL1 FRL2 GDIA1 GDIA2 GDID4 GEFT GIT1 GIT2 GMIP GNA13 GOLGA8R GRAF GRAF2 GRAF3 GRB1 GRF1 GRF2 GRIT GRLF1 GT650 HMHA1 IBP IMD2 IQGAP1 IQGAP2 IQGAP3 ITSN ITSN1 JUP KCTD3 KIAA0004 KIAA0006 KIAA0051 KIAA0131 KIAA0142 KIAA0147 KIAA0148 KIAA0189 KIAA0223 KIAA0294 KIAA0362 KIAA0380 KIAA0382 KIAA0411 KIAA0418 KIAA0424 KIAA0451 KIAA0456 KIAA0554 KIAA0580 KIAA0599 KIAA0621 KIAA0666 KIAA0672 KIAA0694 KIAA0712 KIAA0782 KIAA0915 KIAA1010 KIAA1058 KIAA1112 KIAA1124 KIAA1142 KIAA1156 KIAA1204 KIAA1209 KIAA1264 KIAA1304 KIAA1391 KIAA1395 KIAA1415 KIAA1424 KIAA1478 KIAA1688 KIAA1722 KIAA1723 KIAA1771 KIAA1902 KIAA1909 KIAA2014 KTN1 LAMTOR1 LAP2 LAP4 LARG LBR MAP3K11 MCF2 MCF2L MEGAP MGCRACGAP MLK3 MSE55 MYO9B MYR5 NBR NGEF OPHN1 OPHN1L OPHN3 OST P190A P85SPR PAK1 PAK2 PAK3 PAK3BP PAK4 PAK5 PAK6 PAK7 PAR6A PARD6A PARG1 PDRO PIK3R1 PIK3R2 PIXA PIXB PLD1 PLEKHC2 PLEKHG1 PLEKHG2 PLEKHG3 PLEKHG4 PLEKHG4B PREX1 PREX2 PRTPHN1 PTK1 RAB7 RAB7A RACGAP1 RALBP1 RAP1GN1 RASGRF2 RGC1 RHOGAP1 RHOGAP2 RHOGAP4 RHOGAP5 RICH1 RICH2 RICS RLIP RLIP1 RLIP76 SB1 SCRB1 SCRIB SGEF SH3D1A SH3D20 SH3MD1 SH3PXD2A SHKBP1 SNAP23 SNX26 SPATA13 SPEC2 SPRK SRGAP1 SRGAP2 SRGAP2A SRGAP3 STARD12 STARD13 STARD8 STB2 STEAP3 STOM SYB3 SYDE1 TAGAP TAGAP1 TCGAP TFRC TIAM1 TIM TKS5 TMEM133 TMPO TOCA1 TRIO TSAP6 TUBA VAMP3 VANGL1 VARTUL VAV2 VAV3 WAS WASL WASPIP WBP3 WDR81 WDR91 WICH WIP WIPF1 WIPF2 WIPF3 WIRE XTP8 YKT6 ZFYVE3 ZFYVE4 ZFYVE5 ZFYVE6 ZIZ1 ZIZ2 ZIZ3 ZNF289 p190ARHOGAP	Homo sapiens (human)
Estrogen-dependent gene expression	Apoptosis regulator Bcl-2 Axin-1 BTB/POZ domain-containing protein KCTD6 CREB-binding protein CXXC-type zinc finger protein 5 Cathepsin D Cbp/p300-interacting transactivator 1 Chromodomain-helicase-DNA-binding protein 1 Cohesin subunit SA-1 Cohesin subunit SA-2 Core-binding factor subunit beta Cyclic AMP-dependent transcription factor ATF-2 Cyclin-T1 Cyclin-dependent kinase 9 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Double-strand-break repair protein rad21 homolog Estrogen receptor G1/S-specific cyclin-D1 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Glycerol-3-phosphate acyltransferase 1, mitochondrial Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Helicase MOV-10 Hepatocyte nuclear factor 3-alpha Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Histone acetyltransferase KAT2B Histone acetyltransferase KAT5 Histone acetyltransferase p300 Histone deacetylase 1 Histone-arginine methyltransferase CARM1 Importin subunit alpha-1 KN motif and ankyrin repeat domain-containing protein 1 Lysine-specific demethylase 4B Lysine-specific histone demethylase 1A Mediator of RNA polymerase II transcription subunit 1 Myc proto-oncogene protein Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Nuclear receptor coactivator 3 Nuclear receptor subfamily 5 group A member 2 Nuclear receptor-interacting protein 1 POU domain, class 2, transcription factor 1 Peptidyl-prolyl cis-trans isomerase FKBP4 Probable ATP-dependent RNA helicase DDX5 Progesterone receptor Prostaglandin E synthase 3 Protein FosB Protein GREB1 Protein arginine N-methyltransferase 1 Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Protein c-Fos Protransforming growth factor alpha Receptor-binding cancer antigen expressed on SiSo cells Runt-related transcription factor 1 Stromal cell-derived factor 1 Structural maintenance of chromosomes protein 1A Structural maintenance of chromosomes protein 3 TATA-box-binding protein Trans-acting T-cell-specific transcription factor GATA-3 Transcription factor Jun Transcription factor JunD Transcription factor Sp1 Transcription initiation factor IIA subunit 1 Transcription initiation factor IIA subunit 2 Transcriptional activator Myb Transcriptional repressor protein YY1 Transducin-like enhancer protein 3 Trefoil factor 1 Trefoil factor 3 Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein Upstream stimulatory factor 1 Upstream stimulatory factor 2 Zinc finger protein 217	O00482 O00559 O14646 O15169 O15514 O60216 O60341 O60563 O60814 O75362 O94953 P01100 P01106 P01135 P03372 P04155 P04908 P05412 P06401 P06899 P07339 P07900 P08047 P08238 P0C5Y9 P10242 P10415 P13984 P14859 P15336 P16104 P17535 P17844 P19387 P19388 P20226 P20671 P22415 P23527 P23771 P24385 P24928 P25490 P30876 P33778 P35269 P36954 P48061 P48552 P50750 P52292 P52434 P52435 P52655 P52657 P53539 P53803 P55317 P57053 P58876 P61218 P62487 P62805 P62807 P62875 P68431 P84243 Q01196 Q02790 Q04726 Q07654 Q09472 Q13547 Q13951 Q14678 Q14683 Q15185 Q15596 Q15648 Q15788 Q15853 Q16777 Q16778 Q4ZG55 Q6FI13 Q71DI3 Q71UI9 Q7LFL8 Q86X55 Q8N257 Q8N3U4 Q8NC69 Q8NDV7 Q8WVM7 Q92793 Q92831 Q92993 Q93077 Q93079 Q96A08 Q99873 Q99877 Q99878 Q99879 Q99880 Q99966 Q9BTM1 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9HCL2 Q9UKV8 Q9UL18 Q9UPQ9 Q9UQE7 Q9Y6Q9	AGO1 AGO2 AGO3 AGO4 AIB1 AML1 ANKRD15 AOF2 ARC205 ATF2 AXIN AXIN1 B1F BAM BCEI BCL1 BCL2 BHLHB11 BHLHB12 BHLHE39 BHLHE42 BHLHE74 BHLHE75 BMH CAGH26 CARM1 CBFA2 CBFB CBP CCND1 CCNT1 CDC2L4 CDK9 CHD1 CITED1 CPF CPSD CREB2 CREBBP CREBP1 CRSP1 CRSP200 CSPG6 CTSD CXCL12 CXXC5 DDX5 DRIP205 DRIP230 DXS423E EBAG9 EIF2C1 EIF2C2 EIF2C3 EIF2C4 EP300 ESR ESR1 FKBP4 FKBP52 FOS FOSB FOXA1 FTF G0S3 G0S7 G17P1 GATA3 GPAM GPAT1 GREB1 GTF2A1 GTF2A2 GTF2D1 GTF2F1 GTF2F2 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HDAC1 HELR HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 HLR1 HMT2 HNF3A HR21 HRMT1L2 HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB HTATIP INO80S IR1B4 ITF JHDM3B JMJD2B JUN JUND KANK KANK1 KAT2B KAT5 KCTD6 KDM1 KDM1A KDM4B KIAA0078 KIAA0172 KIAA0178 KIAA0575 KIAA0601 KIAA0876 KIAA1093 KIAA1460 KIAA1547 KIAA1560 KIAA1567 KIAA1582 KIAA1631 KPNA2 LSD1 MED1 MOV10 MSG1 MYB MYC NCOA1 NCOA2 NCOA3 NR3A1 NR3C3 NR5A2 NRIP1 NXP1 OCT1 OTF1 P23 P300 PBP PCAF PGR POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF POU2F1 PPARBP PPARGBP PRAD1 PRMT1 PRMT4 PS2 PTGES3 RAC3 RAD21 RAP30 RAP74 RB18A RCAS1 RCH1 RPB7 RPD3L1 RUNX1 SA1 SA2 SB1.8 SCC1 SCC3 SDF1 SDF1A SDF1B SMC1 SMC1A SMC1L1 SMC3 SMC3L1 SP1 SRC1 SRC2 SRP1 STAG1 STAG2 TAK TBP TCF3A TEBP TF2A1 TF2A2 TF2D TFF1 TFF3 TFI TFIID TGFA TIF2 TIP60 TLE3 TNRC6 TNRC6A TNRC6B TNRC6C TRAM1 TRAP220 TRIP2 TSFP1 TSH2B USF USF1 USF2 YY1 ZABC1 ZNF217	Homo sapiens (human)
Elevation of cytosolic Ca2+ levels	Calcium release-activated calcium channel protein 1 Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 P2X purinoceptor 1 P2X purinoceptor 2 P2X purinoceptor 3 P2X purinoceptor 4 P2X purinoceptor 5 P2X purinoceptor 6 P2X purinoceptor 7 Protein orai-2 Short transient receptor potential channel 3 Short transient receptor potential channel 6 Short transient receptor potential channel 7 Stromal interaction molecule 1	O15547 P51575 P56373 Q13507 Q13586 Q14571 Q14573 Q14643 Q93086 Q96D31 Q96SN7 Q99571 Q99572 Q9HCX4 Q9UBL9 Q9Y210	C7orf19 CBCIP2 CRACM1 GOK INSP3R1 ITPR1 ITPR2 ITPR3 ORAI1 ORAI2 P2RX1 P2RX2 P2RX3 P2RX4 P2RX5 P2RX6 P2RX7 P2RXL1 P2X1 P2X2 P2X5 P2X5FL P2X6 STIM1 TMEM142A TMEM142B TRP3 TRP6 TRP7 TRPC3 TRPC6 TRPC7	Homo sapiens (human)
Signaling by SCF-KIT	Chymase GRB2-associated-binding protein 2 GRB2-related adapter protein 2 GRB2-related adapter protein GTPase HRas GTPase NRas Growth factor receptor-bound protein 10 Growth factor receptor-bound protein 7 Mast/stem cell growth factor receptor Kit Matrix metalloproteinase-9 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Protein kinase C alpha type Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Receptor-type tyrosine-protein phosphatase U Serine/threonine-protein kinase Chk1 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Son of sevenless homolog 1 Tyrosine-protein kinase Fer Tyrosine-protein kinase Fes/Fps Tyrosine-protein kinase Fyn Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lck Tyrosine-protein kinase Lyn Tyrosine-protein kinase Tec Tyrosine-protein kinase Yes Tyrosine-protein phosphatase non-receptor type 11	O00459 O14757 O60674 O75791 P01111 P01112 P06239 P06241 P07332 P07947 P07948 P10721 P14780 P15498 P16591 P17252 P23946 P27986 P40763 P42224 P42229 P42336 P42680 P51692 P63000 Q06124 Q07889 Q13322 Q13588 Q14451 Q92569 Q92729 Q9UQC2	APRF CHEK1 CHK1 CLG4B CMA1 CYH CYM FER FES FMI FPS FYN GAB2 GADS GRAP GRAP2 GRB1 GRB10 GRB2L GRB7 GRBIR GRID HRAS HRAS1 JAK2 JTK8 KIAA0207 KIAA0571 KIT LCK LYN MMP9 NRAS PCP2 PIK3CA PIK3R1 PIK3R2 PIK3R3 PKCA PRKACA PRKCA PSCTK4 PTP2C PTPN11 PTPRO PTPRU RAC1 SCFR SHPTP2 SOS1 STAT1 STAT3 STAT5 STAT5A STAT5B TC25 TEC TYK3 VAV VAV1 YES YES1	Homo sapiens (human)
Chromatin modifications during the maternal to zygotic transition (MZT)	Developmental pluripotency-associated protein 3 E3 ubiquitin-protein ligase UHRF1 Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Histone-arginine methyltransferase METTL23 Lysine-specific demethylase 5A Lysine-specific demethylase 5B Lysine-specific demethylase 6A Lysine-specific demethylase 6B Methylcytosine dioxygenase TET3 Protein STPG4 Single-stranded DNA cytosine deaminase Uracil-DNA glycosylase	O15054 O15550 O43151 O60814 P04908 P06899 P0C5Y9 P13051 P16104 P20671 P23527 P29375 P33778 P57053 P58876 P62805 P62807 P68431 P84243 Q16777 Q16778 Q6FI13 Q6W0C5 Q71DI3 Q71UI9 Q86XA0 Q8N257 Q8N801 Q93077 Q93079 Q96A08 Q96T88 Q99877 Q99878 Q99879 Q99880 Q9BTM1 Q9GZX7 Q9UGL1	AICDA AID C17orf95 C2orf61 DGU DPPA3 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 ICBP90 JARID1A JARID1B JMJD3 KDM5A KDM5B KDM6A KDM6B KIAA0346 KIAA0401 METTL23 NP95 PLU1 RBBP2 RBBP2H1 RBP2 RNF106 STELLAR STPG4 TET3 TSH2B UHRF1 UNG UNG1 UNG15 UTX	Homo sapiens (human)
Activated NTRK2 signals through FRS2 and FRS3	BDNF/NT-3 growth factors receptor Brain-derived neurotrophic factor Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 GTPase HRas GTPase NRas Neurotrophin-4 Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O43559 P01111 P01112 P23560 P34130 Q06124 Q07889 Q16620 Q8WU20	BDNF FRS2 FRS3 HRAS HRAS1 NRAS NTF4 NTF5 NTRK2 PTP2C PTPN11 SHPTP2 SOS1 TRKB	Homo sapiens (human)
TGFBR2 MSI Frameshift Mutants in Cancer	TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein	P01137 P37173	TGFB TGFB1 TGFBR2	Homo sapiens (human)
RUNX3 regulates YAP1-mediated transcription	CCN family member 2 Runt-related transcription factor 3 Transcriptional coactivator YAP1 Transcriptional enhancer factor TEF-1 Transcriptional enhancer factor TEF-3 Transcriptional enhancer factor TEF-4 Transcriptional enhancer factor TEF-5 WW domain-containing transcription regulator protein 1	P28347 P29279 P46937 Q13761 Q15561 Q15562 Q99594 Q9GZV5	AML2 CBFA3 CCN2 CTGF HCS24 IGFBP8 PEBP2A3 RTEF1 RUNX3 TAZ TCF13 TCF13L1 TEAD1 TEAD2 TEAD3 TEAD4 TEAD5 TEF1 TEF3 TEF4 TEF5 WWTR1 YAP1 YAP65	Homo sapiens (human)
GSD XV	Glycogen [starch] synthase, muscle Glycogenin-1	P13807 P46976	GYG GYG1 GYS GYS1	Homo sapiens (human)
Signaling by moderate kinase activity BRAF mutants	14-3-3 protein beta/alpha Amyloid beta A4 precursor protein-binding family B member 1-interacting protein BRCA1-associated protein Beta-arrestin-1 Beta-arrestin-2 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Connector enhancer of kinase suppressor of ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase KRas GTPase NRas Integrin alpha-IIb Integrin beta-3 Kinase suppressor of Ras 1 Kinase suppressor of Ras 2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase kinase kinase 11 Phosphatidylethanolamine-binding protein 1 Prohibitin 1 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A Ras-related protein Rap-1b Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Talin-1 Tyrosine-protein kinase CSK Tyrosine-protein kinase JAK2 Vinculin von Willebrand factor	O60674 P01111 P01112 P01116 P02671 P02675 P02679 P02751 P04049 P04275 P05106 P08514 P0DP23 P10398 P12931 P15056 P18206 P27361 P27448 P28482 P30086 P31946 P32121 P35232 P36507 P41240 P46940 P49407 P61224 P62834 Q02750 Q13554 Q13555 Q13557 Q16584 Q6VAB6 Q7Z569 Q7Z5R6 Q8IVT5 Q8WXI2 Q969H4 Q9UQM7 Q9Y490	APBB1IP ARAF ARAF1 ARB2 ARR1 ARR2 ARRB1 ARRB2 BRAF BRAF1 BRAP CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CNK1 CNK2 CNKSR1 CNKSR2 CSK CTAK1 EMK2 ERK1 ERK2 F8VWF FGA FGB FGG FN FN1 GP2B GP3A HRAS HRAS1 IQGAP1 ITGA2B ITGAB ITGB3 JAK2 KIAA0051 KIAA0902 KIAA0968 KIAA1027 KRAS KRAS2 KREV1 KSR KSR1 KSR2 MAP2K1 MAP2K2 MAP3K11 MAPK1 MAPK3 MARK3 MEK1 MEK2 MKK2 MLK3 NRAS PBP PEBP PEBP1 PHB PHB1 PKS PKS2 PREL1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 PTK1 RAF RAF1 RAFB1 RAP1A RAP1B RARP1 RASK2 RIAM RNF52 SPRK SRC SRC1 TLN TLN1 VCL VWF YWHAB	Homo sapiens (human)
Activation of AMPK downstream of NMDARs	5'-AMP-activated protein kinase catalytic subunit alpha-1 5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-1 5'-AMP-activated protein kinase subunit gamma-2 5'-AMP-activated protein kinase subunit gamma-3 Calcium/calmodulin-dependent protein kinase kinase 2 Calmodulin-1	O43741 P0DP23 P54619 P54646 Q13131 Q96RR4 Q9UGI9 Q9UGJ0 Q9Y478	AMPK AMPK1 AMPK2 AMPKG3 CALM CALM1 CAM CAM1 CAMKK2 CAMKKB KIAA0787 PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3	Homo sapiens (human)
Regulation of ornithine decarboxylase (ODC)	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Antizyme inhibitor 1 NAD(P)H dehydrogenase [quinone] 1 Ornithine decarboxylase antizyme 1 Ornithine decarboxylase antizyme 2 Ornithine decarboxylase antizyme 3 Ornithine decarboxylase Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9	A5LHX3 O00231 O00232 O00233 O00487 O14818 O14977 O43242 O75832 O95190 P11926 P15559 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P54368 P55036 P60896 P60900 P61289 P62191 P62195 P62333 Q06323 Q13200 Q14997 Q15008 Q16401 Q8TAA3 Q92530 Q99436 Q99460 Q9UL46 Q9UMX2 Q9UNM6	AZIN1 C7orf76 DIA4 DSS1 HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0077 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NMOR1 NQO1 NU OAZ OAZ1 OAZ2 OAZ3 OAZI OAZIN ODC1 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RING10 RING12 SEM1 SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 X Y Y2 Z	Homo sapiens (human)
Degradation of AXIN	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Axin-1 Axin-2 E3 ubiquitin-protein ligase RNF146 E3 ubiquitin-protein ligase SMURF2 Poly [ADP-ribose] polymerase tankyrase-1 Poly [ADP-ribose] polymerase tankyrase-2 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O15169 O43242 O75832 O95271 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q06323 Q13200 Q14997 Q15008 Q16401 Q8TAA3 Q92530 Q99436 Q99460 Q9H2K2 Q9HAU4 Q9NTX7 Q9UL46 Q9UNM6 Q9Y2T1	AXIN AXIN1 AXIN2 C7orf76 DSS1 HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0077 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NU PARP5A PARP5B PARPL PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RING10 RING12 RNF146 RPS27A SEM1 SHFDG1 SHFM1 SMURF2 SUG1 SUG2 TANK2 TBP1 TBP7 TIN1 TINF1 TNKL TNKS TNKS1 TNKS2 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 Z	Homo sapiens (human)
Phospholipase C-mediated cascade: FGFR1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9	O15520 P05230 P08620 P09038 P10767 P11487 P19174 P31371 Q9GZV9 Q9HCT0 Q9NP95	FGF1 FGF10 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF9 FGFA FGFB HST HST2 HSTF1 HSTF2 HYPF INT2 KS3 PLC1 PLCG1	Homo sapiens (human)
Netrin mediated repulsion signals	Netrin receptor DCC Netrin receptor UNC5A Netrin receptor UNC5B Netrin receptor UNC5C Netrin receptor UNC5D Netrin-1 Proto-oncogene tyrosine-protein kinase Src Tyrosine-protein phosphatase non-receptor type 11	O95185 O95631 P12931 P43146 Q06124 Q6UXZ4 Q6ZN44 Q8IZJ1	DCC IGDCC1 KIAA1777 KIAA1976 NTN1 NTN1L P53RDL1 PTP2C PTPN11 SHPTP2 SRC SRC1 UNC5A UNC5B UNC5C UNC5D UNC5H1 UNC5H2 UNC5H3 UNC5H4	Homo sapiens (human)
Transcriptional regulation of granulopoiesis	CCAAT/enhancer-binding protein alpha CCAAT/enhancer-binding protein beta CCAAT/enhancer-binding protein epsilon Core-binding factor subunit beta Cyclin-dependent kinase 2 Cyclin-dependent kinase 4 Cyclin-dependent kinase inhibitor 1 Endothelial transcription factor GATA-2 Friend leukemia integration 1 transcription factor Granulocyte colony-stimulating factor receptor Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Histone acetyltransferase p300 Histone-lysine N-methyltransferase 2A Interleukin-6 receptor subunit alpha Krueppel-like factor 5 Lymphoid enhancer-binding factor 1 Myc proto-oncogene protein Protein DEK Retinoic acid receptor RXR-alpha Retinoic acid receptor alpha Runt-related transcription factor 1 Signal transducer and activator of transcription 3 T-cell acute lymphocytic leukemia protein 1 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor PU.1 Transcriptional activator Myb Zinc finger protein Gfi-1	O60814 P01106 P04908 P06899 P08887 P0C5Y9 P10242 P10276 P11802 P16104 P17542 P17676 P17947 P19793 P20671 P23527 P23769 P24941 P33778 P35659 P38936 P40763 P49715 P57053 P58876 P62805 P62807 P68431 P84243 Q01094 Q01196 Q01543 Q03164 Q09472 Q13887 Q13951 Q14186 Q14188 Q15744 Q16777 Q16778 Q6FI13 Q71DI3 Q71UI9 Q8N257 Q93077 Q93079 Q96A08 Q99062 Q99684 Q99877 Q99878 Q99879 Q99880 Q9BTM1 Q9UJU2	ALL1 AML1 APRF BHLHA17 BHLHE39 BTEB2 CAP20 CBFA2 CBFB CDK2 CDK4 CDKN1 CDKN1A CDKN2 CEBP CEBPA CEBPB CEBPE CIP1 CKLF CSF3R CXXC7 DEK DP1 DP2 E2F1 EP300 FLI1 GATA2 GCSFR GFI1 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 HRX HTRX IKLF IL6R KLF5 KMT2A LEF1 MDA6 MLL MLL1 MYB MYC NR1B1 NR2B1 P300 PIC1 RARA RBBP3 RUNX1 RXRA SCL SDI1 SPI1 STAT3 TAL1 TCF5 TCL5 TFDP1 TFDP2 TRX1 TSH2B WAF1 ZNF163	Homo sapiens (human)
Defective LFNG causes SCDO3	Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe Neurogenic locus notch homolog protein 1 Neurogenic locus notch homolog protein 2 Neurogenic locus notch homolog protein 3 Neurogenic locus notch homolog protein 4	P46531 Q04721 Q8NES3 Q99466 Q9UM47	INT3 LFNG NOTCH1 NOTCH2 NOTCH3 NOTCH4 TAN1	Homo sapiens (human)
KSRP (KHSRP) binds and destabilizes mRNA	14-3-3 protein zeta/delta Exosome complex component CSL4 Exosome complex component MTR3 Exosome complex component RRP40 Exosome complex component RRP41 Exosome complex component RRP42 Exosome complex component RRP43 Exosome complex component RRP45 Exosome complex component RRP46 Exosome complex component RRP4 Exosome complex exonuclease RRP44 Far upstream element-binding protein 2 Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 14 Poly(A)-specific ribonuclease PARN RAC-alpha serine/threonine-protein kinase m7GpppN-mRNA hydrolase	O95453 P31749 P63104 Q06265 Q13868 Q15024 Q15759 Q16539 Q5RKV6 Q8IU60 Q92945 Q96B26 Q9NPD3 Q9NQT4 Q9NQT5 Q9Y2L1 Q9Y3B2	AKT1 CML28 CSBP CSBP1 CSBP2 CSL4 CSPB1 DAN DCP2 DIS3 EXOSC1 EXOSC2 EXOSC3 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FUBP2 KHSRP KIAA0116 KIAA1008 MAPK11 MAPK14 MTR3 MXI2 NUDT20 OIP2 PARN PKB PMSCL1 PRKM11 RAC RRP4 RRP40 RRP41 RRP42 RRP43 RRP44 RRP46 SAPK2 SAPK2A SAPK2B SKI6 YWHAZ	Homo sapiens (human)
PI-3K cascade:FGFR3	Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 GRB2-associated-binding protein 1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Tyrosine-protein phosphatase non-receptor type 11	O43320 O76093 P05230 P08620 P09038 P27986 P31371 P42336 Q06124 Q13480 Q8WU20 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF2 FGF20 FGF23 FGF4 FGF9 FGFA FGFB FRS2 GAB1 GRB1 HST HSTF1 HYPF KS3 PIK3CA PIK3R1 PTP2C PTPN11 SHPTP2	Homo sapiens (human)
Defective ABCA3 causes SMDP3	Phospholipid-transporting ATPase ABCA3	Q99758	ABC3 ABCA3	Homo sapiens (human)
Signaling by FGFR1 in disease	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 BAG family molecular chaperone regulator 4 Breakpoint cluster region protein Centrosomal protein 43 Cleavage and polyadenylation specificity factor subunit 6 Erlin-2 FGFR1 oncogene partner 2 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor 1 Fibroblast growth factor receptor substrate 2 GRB2-associated-binding protein 1 GTPase HRas GTPase NRas Homeobox protein cut-like 1 Leucine-rich repeat flightless-interacting protein 1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Son of sevenless homolog 1 Transcription intermediary factor 1-alpha Unconventional myosin-XVIIIa Zinc finger MYM-type protein 2	O15164 O94905 O95429 O95684 P01111 P01112 P05230 P08620 P09038 P10767 P11274 P11362 P19174 P27986 P31371 P39880 P42336 Q07889 Q13480 Q16630 Q32MZ4 Q8WU20 Q92614 Q9GZV9 Q9NP95 Q9NVK5 Q9UBW7	BAG4 BCR BCR1 BFGFR C8orf2 CD245 CEK CEP43 CFIM68 CPSF6 CUTL1 CUX1 D22S11 ERLIN2 FGF1 FGF2 FGF20 FGF23 FGF4 FGF6 FGF9 FGFA FGFB FGFBR FGFR1 FGFR1OP FGFR1OP2 FIM FLG FLT2 FOP FRS2 GAB1 GCF2 GRB1 HBGFR HRAS HRAS1 HST HST2 HSTF1 HSTF2 HYPF KIAA0216 KS3 LRRFIP1 MYO18A MYSPDZ NRAS PIK3CA PIK3R1 PLC1 PLCG1 RAMP RNF82 SODD SOS1 SPFH2 TIAF1 TIF1 TIF1A TRIM24 TRIP ZMYM2 ZNF198	Homo sapiens (human)
TNFR1-induced proapoptotic signaling	Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 Caspase-8 E3 ubiquitin-protein ligase MIB2 E3 ubiquitin-protein ligase RNF31 E3 ubiquitin-protein ligase XIAP FAS-associated death domain protein Inhibitor of nuclear factor kappa-B kinase subunit epsilon OTU domain-containing protein 1 OTU domain-containing protein 7B Optineurin RanBP-type and C3HC4-type zinc finger-containing protein 1 Receptor-interacting serine/threonine-protein kinase 1 Serine/threonine-protein kinase TBK1 Sharpin Spermatogenesis-associated protein 2 TNF receptor-associated factor 2 Tumor necrosis factor alpha-induced protein 3 Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor Ubiquitin carboxyl-terminal hydrolase 21 Ubiquitin carboxyl-terminal hydrolase 2 Ubiquitin carboxyl-terminal hydrolase 4 Ubiquitin carboxyl-terminal hydrolase CYLD Uncharacterized protein UL36	O75604 P01375 P16767 P19438 P21580 P98170 Q12933 Q13107 Q13158 Q13489 Q13490 Q13546 Q14164 Q14790 Q15628 Q5VV17 Q6GQQ9 Q96AX9 Q96CV9 Q96EP0 Q9BYM8 Q9H0F6 Q9NQC7 Q9UHD2 Q9UK80 Q9UM82	API1 API2 API3 BIRC2 BIRC3 BIRC4 C20orf18 CASP8 CYLD CYLD1 DUBA7 FADD FIP2 GLC1E HIP7 HYPL IAP3 IKBKE IKKE IKKI KIAA0151 KIAA0757 KIAA0849 MCH5 MIB2 MIHB MIHC MORT1 NAK NRP OPTN OTDC1 OTUD1 OTUD7B OTUD7C PD1 RBCK1 RIP RIP1 RIPK1 RNF31 RNF48 RNF49 RNF54 SHARPIN SIPL1 SKD SPATA2 TBK1 TNF TNFA TNFAIP3 TNFAR TNFR1 TNFRSF1A TNFSF2 TRADD TRAF2 TRAP3 UBCE7IP3 UBP41 UL36 UNP UNPH USP2 USP21 USP23 USP4 XAP3 XAP4 XIAP ZA20D1 ZIBRA ZZANK1	Homo sapiens (human)
Serotonin receptors	5-hydroxytryptamine receptor 1A 5-hydroxytryptamine receptor 1B 5-hydroxytryptamine receptor 1D 5-hydroxytryptamine receptor 1E 5-hydroxytryptamine receptor 1F 5-hydroxytryptamine receptor 2A 5-hydroxytryptamine receptor 2B 5-hydroxytryptamine receptor 2C 5-hydroxytryptamine receptor 4 5-hydroxytryptamine receptor 5A 5-hydroxytryptamine receptor 6 5-hydroxytryptamine receptor 7	P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P47898 P50406 Q13639	ADRB2RL1 ADRBRL1 HTR1A HTR1B HTR1C HTR1D HTR1DA HTR1DB HTR1E HTR1EL HTR1F HTR2 HTR2A HTR2B HTR2C HTR4 HTR5A HTR6 HTR7 HTRL	Homo sapiens (human)
Resistance of ERBB2 KD mutants to sapitinib	Erbin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Receptor tyrosine-protein kinase erbB-2	P04626 P07900 Q16543 Q96RT1	CDC37 CDC37A ERBB2 ERBB2IP ERBIN HER2 HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NEU NGL	Homo sapiens (human)
Regulation of APC/C activators between G1/S and early anaphase	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 1 Cyclin-dependent kinase 2 F-box only protein 5 Fizzy-related protein homolog G2/mitotic-specific cyclin-B1 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S	O00762 P06493 P14635 P20248 P24941 P30260 P51668 P51965 P60006 P78396 Q12834 Q13042 Q16763 Q8NHZ8 Q96DE5 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UKT4 Q9UM11 Q9UM13	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 C10orf104 C11orf51 C9orf17 CCN1 CCNA CCNA1 CCNA2 CCNB CCNB1 CDC16 CDC2 CDC20 CDC23 CDC26 CDC27 CDC28A CDH1 CDK1 CDK2 CDKN1 CDKN2 CENP-27 D0S1430E D17S978E E2EPF EMI1 FBX5 FBXO5 FYR FZR FZR1 KIAA1242 KIAA1406 P34CDC2 SFT TSG24 UBC5A UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S	Homo sapiens (human)

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