GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1151 - 1175** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Signaling by extracellular domain mutants of KIT	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Activation of gene expression by SREBF (SREBP)	3'-5' exoribonuclease HELZ2 7-dehydrocholesterol reductase Acetyl-CoA carboxylase 1 Acetyl-CoA carboxylase 2 CREB-binding protein Chromodomain-helicase-DNA-binding protein 9 Delta(14)-sterol reductase TM7SF2 Diphosphomevalonate decarboxylase F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Farnesyl pyrophosphate synthase Fatty acid synthase Geranylgeranyl pyrophosphate synthase Glycerol-3-phosphate acyltransferase 1, mitochondrial Histone-arginine methyltransferase CARM1 Hydroxymethylglutaryl-CoA synthase, cytoplasmic Isopentenyl-diphosphate Delta-isomerase 1 Lanosterol 14-alpha demethylase Lanosterol synthase Lathosterol oxidase Mediator of RNA polymerase II transcription subunit 1 Metal regulatory transcription factor 1 Mevalonate kinase Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Nuclear receptor coactivator 6 Nuclear transcription factor Y subunit alpha Nuclear transcription factor Y subunit beta Nuclear transcription factor Y subunit gamma Peroxisome proliferator-activated receptor alpha Phosphomevalonate kinase Retinoic acid receptor RXR-alpha SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 Squalene monooxygenase Squalene synthase Stearoyl-CoA desaturase Sterol regulatory element-binding protein 2 Transcription factor Sp1 Trimethylguanosine synthase Very long chain fatty acid elongase 6	O00763 O00767 O60907 O75845 O76062 O95749 P08047 P14324 P19793 P23511 P25208 P37268 P48449 P49327 P53602 Q01581 Q03426 Q07869 Q12772 Q13085 Q13907 Q13952 Q14534 Q14686 Q14872 Q15126 Q15596 Q15648 Q15788 Q16850 Q3L8U1 Q6STE5 Q86X55 Q92793 Q96RS0 Q9BYK8 Q9BZK7 Q9H5J4 Q9HCL2 Q9UBM7	ACAC ACACA ACACB ACC1 ACC2 ACCA ACCB AIB3 ANG1 ARC205 BAF60C BHLHD2 BHLHE74 BHLHE75 CARM1 CBP CHD9 CREBBP CRSP1 CRSP200 CYP51 CYP51A1 D7SR DHCR7 DRIP205 DRIP230 ELOVL6 ERG1 FACE FADS5 FAS FASN FDFT1 FDPS FPS GGPS1 GPAM GPAT1 HAP3 HCA137 HELZ2 HMGCS HMGCS1 IDI1 IRA1 KIAA0181 KIAA0308 KIAA1293 KIAA1560 KIAA1769 KISH2 LCE LSS MED1 MPD MTF1 MVD MVK NCOA1 NCOA2 NCOA6 NCOA6IP NFYA NFYB NFYC NR1C1 NR2B1 OSC PBP PIMT PMKI PMVK PPAR PPARA PPARBP PPARGBP PRIC285 PRIC320 PRMT4 RAP250 RB18A RXRA SC5D SC5DL SCD SCD1 SCDOS SMARCD3 SP1 SQLE SRC1 SRC2 SREBF2 SREBP2 TBL1 TBL1X TBL1XR1 TBLR1 TGS1 TIF2 TM7SF2 TRAP220 TRBP TRIP2 TSFP1	Homo sapiens (human)
Gap junction assembly	Gap junction alpha-1 protein Gap junction alpha-10 protein Gap junction alpha-3 protein Gap junction alpha-4 protein Gap junction alpha-5 protein Gap junction alpha-8 protein Gap junction alpha-9 protein Gap junction beta-1 protein Gap junction beta-2 protein Gap junction beta-3 protein Gap junction beta-4 protein Gap junction beta-5 protein Gap junction beta-6 protein Gap junction beta-7 protein Gap junction delta-2 protein Gap junction delta-3 protein Gap junction delta-4 protein Gap junction gamma-1 protein Gap junction gamma-2 protein	O75712 O95377 O95452 P08034 P17302 P29033 P35212 P36382 P36383 P48165 P57773 Q5T442 Q6PEY0 Q8N144 Q969M2 Q96KN9 Q9NTQ9 Q9UKL4 Q9Y6H8	CX25 CX31 CX32 CX40.1 CX62 GJA1 GJA10 GJA11 GJA12 GJA3 GJA4 GJA5 GJA7 GJA8 GJA9 GJAL GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 GJC1 GJC2 GJD2 GJD3 GJD4	Homo sapiens (human)
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-2 E3 ubiquitin-protein ligase RBX1 Egl nine homolog 1 Elongin-B Elongin-C Endothelial PAS domain-containing protein 1 Hypoxia-inducible factor 1-alpha Hypoxia-inducible factor 3-alpha LIM domain-containing protein 1 LIM domain-containing protein ajuba Polyubiquitin-B Polyubiquitin-C Prolyl hydroxylase EGLN2 Prolyl hydroxylase EGLN3 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Wilms tumor protein 1-interacting protein von Hippel-Lindau disease tumor suppressor	A5LHX3 A6NIX2 O00231 O00232 O00233 O00487 O14818 O43242 O75832 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P40337 P43686 P48556 P49720 P49721 P51665 P51668 P55036 P60896 P60900 P61077 P61289 P62191 P62195 P62333 P62837 P62877 P62979 P62987 Q06323 Q13200 Q13617 Q14997 Q15008 Q15369 Q15370 Q16401 Q16665 Q8TAA3 Q92530 Q96IF1 Q96KS0 Q99436 Q99460 Q99814 Q9GZT9 Q9H6Z9 Q9UGP4 Q9UL46 Q9UNM6 Q9Y2N7	AJUBA BHLHE17 BHLHE73 BHLHE78 C1orf12 C7orf76 CUL2 DSS1 EGLN1 EGLN2 EGLN3 EIT6 ELOB ELOC EPAS1 HC2 HC3 HC8 HC9 HIF1A HIF2A HIF3A HSPC IFI5111 JUB KIAA0072 KIAA0077 KIAA0107 LIMD1 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOP1 MOP2 MOP7 MOV34L MSS1 NU PASD2 PASD7 PASD8 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 PUBC1 RBX1 RING10 RING12 RNF75 ROC1 RPS27A SEM1 SFT SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TCEB1 TCEB2 TRAP2 UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBC5C UBCEP1 UBCEP2 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBE2D1 UBE2D2 UBE2D3 VHL WTIP X Y Y2 Z	Homo sapiens (human)
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6	Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 Cyclin-dependent kinase inhibitor 2A	P11802 P42771 Q00534	CDK4 CDK6 CDKN2 CDKN2A CDKN6 MTS1	Homo sapiens (human)
Assembly of collagen fibrils and other multimeric structures	CD151 antigen Cathepsin B Cathepsin L2 Cathepsin S Collagen alpha-1(I) chain Collagen alpha-1(II) chain Collagen alpha-1(III) chain Collagen alpha-1(IV) chain Collagen alpha-1(IX) chain Collagen alpha-1(V) chain Collagen alpha-1(VI) chain Collagen alpha-1(VIII) chain Collagen alpha-1(X) chain Collagen alpha-1(XI) chain Collagen alpha-1(XV) chain Collagen alpha-1(XVIII) chain Collagen alpha-1(XXIV) chain Collagen alpha-1(XXVII) chain Collagen alpha-2(I) chain Collagen alpha-2(IV) chain Collagen alpha-2(IX) chain Collagen alpha-2(V) chain Collagen alpha-2(VI) chain Collagen alpha-2(VIII) chain Collagen alpha-2(XI) chain Collagen alpha-3(IV) chain Collagen alpha-3(IX) chain Collagen alpha-3(V) chain Collagen alpha-3(VI) chain Collagen alpha-4(IV) chain Collagen alpha-5(IV) chain Collagen alpha-5(VI) chain Collagen alpha-6(VI) chain Collagenase 3 Integrin alpha-6 Integrin beta-4 Laminin subunit alpha-3 Laminin subunit beta-3 Laminin subunit gamma-2 Matrilysin Matrix metalloproteinase-20 Matrix metalloproteinase-9 Plectin Procathepsin L Stromelysin-1	A6NMZ7 A8TX70 O60882 O60911 P02452 P02458 P02461 P02462 P05997 P07711 P07858 P08123 P08254 P08572 P09237 P12107 P12109 P12110 P12111 P13942 P14780 P16144 P20849 P20908 P23229 P25067 P25774 P25940 P27658 P29400 P39059 P39060 P45452 P48509 P53420 Q01955 Q03692 Q13751 Q13753 Q14050 Q14055 Q15149 Q16787 Q17RW2 Q8IZC6	C3orf7 CATL2 CD151 CLG4B COL10A1 COL11A1 COL11A2 COL15A1 COL18A1 COL1A1 COL1A2 COL24A1 COL27A1 COL29A1 COL2A1 COL3A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL5A1 COL5A2 COL5A3 COL6A1 COL6A2 COL6A3 COL6A5 COL6A6 COL8A1 COL8A2 COL9A1 COL9A2 COL9A3 COLL6 CPSB CTSB CTSL CTSL1 CTSL2 CTSS CTSU CTSV ITGA6 ITGB4 KIAA1870 LAMA3 LAMB2T LAMB3 LAMC2 LAMNA LAMNB1 LAMNB2 MMP13 MMP20 MMP3 MMP7 MMP9 MPSL1 PLEC PLEC1 PUMP1 STMY1 TSPAN24 VWA4	Homo sapiens (human)
Removal of the Flap Intermediate from the C-strand	Adrenocortical dysplasia protein homolog Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 DNA replication ATP-dependent helicase/nuclease DNA2 Flap endonuclease 1 Proliferating cell nuclear antigen Protection of telomeres protein 1 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit TERF1-interacting nuclear factor 2 Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2	P12004 P15927 P27694 P28340 P35244 P39748 P49005 P51530 P54274 Q14191 Q15054 Q15554 Q96AP0 Q9BSI4 Q9HCU8 Q9NUX5 Q9NYB0	ACD DNA2 DNA2L DRIP5 FEN1 KIAA0039 KIAA0083 PCNA PIN2 PIP1 POLD POLD1 POLD2 POLD3 POLD4 POLDS POT1 PTOP RAD2 RAP1 RECQ3 RECQL2 REPA1 REPA2 REPA3 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 TERF1 TERF2 TERF2IP TIN2 TINF2 TINT1 TPP1 TRBF1 TRBF2 TRF TRF1 TRF2 WRN	Homo sapiens (human)
Ub-specific processing proteases	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Androgen receptor Antiviral innate immune response receptor RIG-I Ataxin-7 Axin-1 Axin-2 Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 Beclin-1 Beta-2 adrenergic receptor Beta-arrestin-1 Beta-arrestin-2 CAAX prenyl protease 2 Cell division cycle protein 20 homolog Cellular tumor antigen p53 Centriolar coiled-coil protein of 110 kDa Claspin Cyclin-A1 Cyclin-A2 Cystic fibrosis transmembrane conductance regulator DNA damage-binding protein 2 DNA polymerase beta E3 ubiquitin-protein ligase Mdm2 E3 ubiquitin-protein ligase RNF123 E3 ubiquitin-protein ligase RNF128 E3 ubiquitin-protein ligase RNF146 E3 ubiquitin-protein ligase SIAH2 E3 ubiquitin-protein ligase SMURF2 Forkhead box protein O4 Hepatocyte growth factor-regulated tyrosine kinase substrate Histone H2A type 1-A Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-H Histone H2A type 1-J Histone H2A type 1 Histone H2A type 2-A Histone H2A type 2-B Histone H2A type 2-C Histone H2A type 3 Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 2-F Histone H2B type 3-B Histone acetyltransferase KAT2A Hypoxia-inducible factor 1-alpha Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4 Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 8 Insulin-degrading enzyme Interferon-induced helicase C domain-containing protein 1 Interleukin-33 Kelch-like ECH-associated protein 1 M-phase inducer phosphatase 1 Methionine adenosyltransferase 2 subunit beta Mitochondrial Rho GTPase 1 Mitochondrial import receptor subunit TOM20 homolog Mitochondrial import receptor subunit TOM70 Mitochondrial ubiquitin ligase activator of NFKB 1 Mitogen-activated protein kinase kinase kinase 7 Mothers against decapentaplegic homolog 1 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Mothers against decapentaplegic homolog 7 Myc proto-oncogene protein NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Peptidyl-prolyl cis-trans isomerase FKBP8 Peptidyl-tRNA hydrolase 2, mitochondrial Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Poly [ADP-ribose] polymerase tankyrase-1 Poly [ADP-ribose] polymerase tankyrase-2 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein Mdm4 Receptor-interacting serine/threonine-protein kinase 1 RuvB-like 1 S-phase kinase-associated protein 2 Signal transducing adapter molecule 2 Sin3 histone deacetylase corepressor complex component SDS3 Sorting nexin-3 TGF-beta receptor type-1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TNF receptor-associated factor 2 TNF receptor-associated factor 6 Trans-acting T-cell-specific transcription factor GATA-3 Transcription initiation factor TFIID subunit 10 Transcription initiation factor TFIID subunit 9B Transcriptional adapter 2-beta Transcriptional adapter 3 Transformation/transcription domain-associated protein Ubiquitin carboxyl-terminal hydrolase 10 Ubiquitin carboxyl-terminal hydrolase 11 Ubiquitin carboxyl-terminal hydrolase 12 Ubiquitin carboxyl-terminal hydrolase 13 Ubiquitin carboxyl-terminal hydrolase 14 Ubiquitin carboxyl-terminal hydrolase 15 Ubiquitin carboxyl-terminal hydrolase 16 Ubiquitin carboxyl-terminal hydrolase 17-like protein 10 Ubiquitin carboxyl-terminal hydrolase 17-like protein 11 Ubiquitin carboxyl-terminal hydrolase 17-like protein 12 Ubiquitin carboxyl-terminal hydrolase 17-like protein 13 Ubiquitin carboxyl-terminal hydrolase 17-like protein 15 Ubiquitin carboxyl-terminal hydrolase 17-like protein 17 Ubiquitin carboxyl-terminal hydrolase 17-like protein 18 Ubiquitin carboxyl-terminal hydrolase 17-like protein 19 Ubiquitin carboxyl-terminal hydrolase 17-like protein 1 Ubiquitin carboxyl-terminal hydrolase 17-like protein 20 Ubiquitin carboxyl-terminal hydrolase 17-like protein 21 Ubiquitin carboxyl-terminal hydrolase 17-like protein 22 Ubiquitin carboxyl-terminal hydrolase 17-like protein 24 Ubiquitin carboxyl-terminal hydrolase 17-like protein 3 Ubiquitin carboxyl-terminal hydrolase 17-like protein 5 Ubiquitin carboxyl-terminal hydrolase 17 Ubiquitin carboxyl-terminal hydrolase 19 Ubiquitin carboxyl-terminal hydrolase 20 Ubiquitin carboxyl-terminal hydrolase 21 Ubiquitin carboxyl-terminal hydrolase 22 Ubiquitin carboxyl-terminal hydrolase 24 Ubiquitin carboxyl-terminal hydrolase 25 Ubiquitin carboxyl-terminal hydrolase 26 Ubiquitin carboxyl-terminal hydrolase 28 Ubiquitin carboxyl-terminal hydrolase 2 Ubiquitin carboxyl-terminal hydrolase 30 Ubiquitin carboxyl-terminal hydrolase 33 Ubiquitin carboxyl-terminal hydrolase 34 Ubiquitin carboxyl-terminal hydrolase 37 Ubiquitin carboxyl-terminal hydrolase 3 Ubiquitin carboxyl-terminal hydrolase 42 Ubiquitin carboxyl-terminal hydrolase 44 Ubiquitin carboxyl-terminal hydrolase 47 Ubiquitin carboxyl-terminal hydrolase 48 Ubiquitin carboxyl-terminal hydrolase 49 Ubiquitin carboxyl-terminal hydrolase 4 Ubiquitin carboxyl-terminal hydrolase 5 Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin carboxyl-terminal hydrolase 8 Ubiquitin carboxyl-terminal hydrolase 9X Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin recognition factor in ER-associated degradation protein 1 Ubiquitin thioesterase OTUB1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Ubl carboxyl-terminal hydrolase 18 Voltage-dependent anion-selective channel protein 1 Voltage-dependent anion-selective channel protein 2 Voltage-dependent anion-selective channel protein 3 WD repeat-containing protein 20 WD repeat-containing protein 48	A5LHX3 A6NCW0 A6NCW7 A8MUK1 C9J2P7 C9JJH3 C9JLJ4 C9JPN9 C9JVI0 D6R901 D6R9N7 D6RA61 D6RBQ6 D6RCP7 D6RJB6 O00231 O00232 O00233 O00487 O14818 O14964 O15105 O15151 O15169 O15265 O43242 O43255 O43303 O43318 O60493 O60814 O75317 O75528 O75604 O75832 O75886 O94826 O94966 O95271 O95760 O95786 P01106 P04637 P04908 P06746 P06899 P07550 P0C0S8 P0C7I0 P0CG47 P0CG48 P10275 P13569 P14735 P17980 P20248 P20618 P20671 P21796 P23527 P23771 P25786 P25787 P25788 P25789 P25963 P28062 P28065 P28066 P28070 P28072 P28074 P30304 P32121 P33778 P35998 P36897 P40306 P40818 P43686 P45880 P45974 P48556 P49407 P49720 P49721 P51665 P51784 P54578 P55036 P58876 P60484 P60896 P60900 P61289 P62191 P62195 P62333 P62807 P62979 P62987 P78396 P84022 P98177 Q00987 Q06323 Q0WX57 Q12834 Q12933 Q12962 Q13107 Q13200 Q13309 Q13485 Q13489 Q13490 Q13546 Q14145 Q14318 Q14457 Q14694 Q14997 Q15008 Q15388 Q15750 Q15796 Q15797 Q16186 Q16401 Q16665 Q16777 Q16778 Q5QNW6 Q5XPI4 Q6FI13 Q6R6M4 Q70CQ1 Q70CQ2 Q70CQ3 Q7L7L0 Q7RTZ2 Q86T82 Q86TJ2 Q86UV5 Q8IUE6 Q8IXI2 Q8N257 Q8TAA3 Q8TAF3 Q8TBZ3 Q8TEB7 Q8TEY7 Q92466 Q92530 Q92830 Q92890 Q92995 Q93008 Q93009 Q93077 Q93079 Q969V5 Q96A08 Q96FW1 Q96K76 Q96KK5 Q96QV6 Q96RU2 Q99436 Q99460 Q99877 Q99878 Q99879 Q99880 Q9BXU7 Q9BYX4 Q9H0E7 Q9H2K2 Q9H7L9 Q9H9J4 Q9HAU4 Q9HAW4 Q9HBM6 Q9NQC7 Q9NTX7 Q9NZL9 Q9UHP3 Q9UK80 Q9UL46 Q9UMW8 Q9UNM6 Q9UPT9 Q9UPU5 Q9Y256 Q9Y265 Q9Y277 Q9Y2K6 Q9Y2T1 Q9Y3E5 Q9Y4A5 Q9Y4E8 Q9Y4K3 Q9Y5T5 Q9Y6I4 Q9Y6K9	ABCC7 ADA2B ADA3 ADRB2 ADRB2R ADRM1 AFX AFX1 ALK5 API1 API2 AR ARB2 ARHT1 ARR1 ARR2 ARRB1 ARRB2 ATXN7 AXIN AXIN1 AXIN2 B2AR BECN1 BHLHE39 BHLHE78 BIRC2 BIRC3 BIT1 BSP1 C1orf166 C7orf76 C9orf26 CCN1 CCNA CCNA1 CCNA2 CCP110 CDC20 CDC25A CEP110 CFTR CLSPN CP110 CYLD CYLD1 DDB2 DDX58 DFFRX DHTR DPC4 DSS1 DUB3 FACE2 FAM FBXL1 FIP3 FKBP38 FKBP8 FOXO4 GATA3 GCN5 GCN5L2 GIDE GP110 GT197 H2AC1 H2AC11 H2AC12 H2AC13 H2AC14 H2AC15 H2AC16 H2AC17 H2AC18 H2AC19 H2AC20 H2AC21 H2AC25 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFC H2AFD H2AFE H2AFG H2AFI H2AFL H2AFM H2AFN H2AFO H2AFP H2AFQ H2AFR H2AW H2BC1 H2BC10 H2BC11 H2BC12 H2BC13 H2BC14 H2BC15 H2BC17 H2BC18 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFT H2BU1 HAUSP HBP HC2 HC3 HC8 HC9 HGS HIF1A HIRIP1 HIRIP2 HIST1H2AA HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AG HIST1H2AH HIST1H2AI HIST1H2AJ HIST1H2AK HIST1H2AL HIST1H2AM HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AB HIST2H2AC HIST2H2BE HIST2H2BF HIST3H2A HIST3H2BB HRS HSPC IDE IFI5111 IFIH1 IKBA IKBKG IL1F11 IL33 INO80H INRF2 ISG43 ISOT ISOT3 KAT2A KEAP1 KIAA0016 KIAA0055 KIAA0072 KIAA0077 KIAA0107 KIAA0132 KIAA0190 KIAA0419 KIAA0529 KIAA0570 KIAA0719 KIAA0729 KIAA0849 KIAA0891 KIAA1003 KIAA1057 KIAA1063 KIAA1097 KIAA1449 KIAA1515 KIAA1594 KLHL19 KPC1 LMP10 LMP2 LMP7 LMPX LMPY LSFR3A MAD3 MADH1 MADH2 MADH3 MADH4 MADH7 MADH8 MADR1 MADR2 MAP3K7 MAP3K7IP1 MAPL MAT2B MB1 MCB1 MDA5 MDM2 MDM4 MDMX MECL1 MIHB MIHC MIP224 MLLT7 MMAC1 MOP1 MOV34L MSS1 MUL1 MULAN MYC NEMO NFHEV NFKBI NFKBIA NMP238 NR3C4 NU OTB1 OTU1 OTUB1 P53 PAF400 PARP5A PARP5B PARPL PASD8 PFAAP4 POH1 POLB PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 PTEN PTH2 PTRH2 RCE1 RCE1A RCE1B RH116 RHOT1 RIGI RING10 RING12 RIP RIP1 RIPK1 RNF123 RNF128 RNF146 RNF218 RNF48 RNF49 RNF85 RPS27A RUVBL1 SAP45 SCA7 SDS3 SEM1 SHFDG1 SHFM1 SIAH2 SKP2 SKR4 SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 SMURF2 SNX3 STAM2 SUDS3 SUG1 SUG2 TAB1 TADA2B TADA3 TADA3L TAF10 TAF2A TAF2H TAF9B TAF9L TAFII30 TAK1 TANK2 TBP1 TBP7 TEP1 TGFBR1 TGR TGT TIN1 TINF1 TIP49 TIP49A TNKL TNKS TNKS1 TNKS2 TOM70 TOMM20 TOMM70 TOMM70A TP53 TRAF2 TRAF6 TRAP2 TRAP3 TRRAP TSH2B UAF1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBH1 UBP41 UBPY UFD1 UFD1L UHX1 UNP UNPH USP10 USP11 USP12 USP12L1 USP13 USP14 USP15 USP16 USP17 USP17B USP17F USP17H USP17I USP17J USP17K USP17L USP17L1 USP17L10 USP17L11 USP17L12 USP17L13 USP17L15 USP17L17 USP17L18 USP17L19 USP17L1P USP17L2 USP17L20 USP17L21 USP17L22 USP17L24 USP17L25 USP17L26 USP17L27 USP17L28 USP17L29 USP17L3 USP17L30 USP17L4 USP17L5 USP17L8 USP17M USP18 USP19 USP2 USP20 USP21 USP22 USP23 USP24 USP25 USP26 USP28 USP3 USP30 USP31 USP33 USP34 USP37 USP3L USP4 USP42 USP44 USP47 USP48 USP49 USP5 USP7 USP8 USP9 USP9X VDAC VDAC1 VDAC2 VDAC3 VDU1 VDU2 WDR20 WDR48 X Y Y2 Z ZMYND9	Homo sapiens (human)
Regorafenib-resistant KIT mutants	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
RHO GTPases Activate NADPH Oxidases	Cytochrome b-245 heavy chain Cytochrome b-245 light chain Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 14 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 NADPH oxidase 1 NADPH oxidase 3 NADPH oxidase activator 1 NADPH oxidase organizer 1 Neutrophil cytosol factor 1 Neutrophil cytosol factor 2 Neutrophil cytosol factor 4 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphoinositide 3-kinase regulatory subunit 4 Protein S100-A8 Protein S100-A9 Protein kinase C alpha type Protein kinase C beta type Protein kinase C delta type Protein kinase C zeta type Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 2	P04839 P05109 P05771 P06702 P13498 P14598 P15153 P17252 P19878 P27361 P28482 P63000 Q05513 Q05655 Q13526 Q15080 Q15759 Q16539 Q86UR1 Q8NEB9 Q8NFA2 Q99570 Q9HBY0 Q9Y5S8	CAGA CAGB CFAG CSBP CSBP1 CSBP2 CSPB1 CYBA CYBB ERK1 ERK2 MAPK1 MAPK11 MAPK14 MAPK3 MOX1 MOX2 MRP14 MRP8 MXI2 NCF1 NCF2 NCF4 NOH1 NOX1 NOX2 NOX3 NOXA1 NOXA2 NOXO1 NOXO2 P41NOX P51NOX P67PHOX PIK3C3 PIK3R4 PIN1 PKC2 PKCA PKCB PKCD PRKACA PRKCA PRKCB PRKCB1 PRKCD PRKCZ PRKM1 PRKM11 PRKM2 PRKM3 RAC1 RAC2 S100A8 S100A9 SAPK2 SAPK2A SAPK2B SH3PXD1A SH3PXD4 SH3PXD5 TC25 VPS15 VPS34	Homo sapiens (human)
SMAD2/3 MH2 Domain Mutants in Cancer	Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4	P84022 Q13485 Q15796	DPC4 MADH2 MADH3 MADH4 MADR2 SMAD2 SMAD3 SMAD4	Homo sapiens (human)
Dermatan sulfate biosynthesis	Biglycan Brevican core protein Carbohydrate sulfotransferase 14 Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Dermatan-sulfate epimerase-like protein Dermatan-sulfate epimerase Neurocan core protein Uronyl 2-sulfotransferase Versican core protein	O14594 O95196 P07585 P13611 P21810 Q6UVK1 Q8IZU8 Q8NCH0 Q96GW7 Q9UL01 Q9Y2C2	BCAN BEHAB BGN C18orf4 CALEB CHST14 CSPG2 CSPG3 CSPG4 CSPG5 CSPG7 D4ST1 DCN DS2ST DSE DSEL MCSP NCAG1 NCAN NEUR NGC SART2 SLRR1A SLRR1B UST VCAN	Homo sapiens (human)
Recognition and association of DNA glycosylase with site containing an affected purine	Adrenocortical dysplasia protein homolog DNA-3-methyladenine glycosylase Endonuclease 8-like 3 Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1t Histone H4 N-glycosylase/DNA lyase Protection of telomeres protein 1 TERF1-interacting nuclear factor 2 Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2	O15527 O60814 P04908 P06899 P0C5Y9 P16104 P20671 P23527 P29372 P33778 P54274 P57053 P58876 P62805 P62807 Q15554 Q16695 Q16777 Q16778 Q6FI13 Q71UI9 Q8N257 Q8TAT5 Q93077 Q93079 Q96A08 Q96AP0 Q99877 Q99878 Q99879 Q99880 Q9BSI4 Q9BTM1 Q9NUX5 Q9NYB0	AAG ACD ANPG DRIP5 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-4 H3FT H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST3H3 HIST4H4 MID1 MMH MPG MUTM NEIL3 OGG1 OGH1 PIN2 PIP1 POT1 PTOP RAP1 TERF1 TERF2 TERF2IP TIN2 TINF2 TINT1 TPP1 TRBF1 TRBF2 TRF TRF1 TRF2 TSH2B	Homo sapiens (human)
Translation of Replicase and Assembly of the Replication Transcription Complex	Beclin-1 Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4a Charged multivesicular body protein 4b Charged multivesicular body protein 4c Charged multivesicular body protein 6 Charged multivesicular body protein 7 Microtubule-associated proteins 1A/1B light chain 3B ORF8b protein ORF9b protein Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphoinositide 3-kinase regulatory subunit 4 Replicase polyprotein 1a Replicase polyprotein 1ab UV radiation resistance-associated gene protein	O43633 P0C6U8 P0C6X7 P59636 Q14457 Q80H93 Q8NEB9 Q8WUX9 Q96CF2 Q96FZ7 Q99570 Q9BY43 Q9GZQ8 Q9H444 Q9P2Y5 Q9UQN3 Q9Y3E7	1a 8b 9b BC2 BECN1 C14orf123 C20orf178 CGI149 CHMP2 CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP6 CHMP7 GT197 MAP1ALC3 MAP1LC3B NEDF PIK3C3 PIK3R4 SHAX1 SHAX2 SHAX3 UVRAG VPS15 VPS20 VPS24 VPS34 rep	Homo sapiens (human)
CDC6 association with the ORC:origin complex	Cell division control protein 6 homolog DNA helicase MCM8 Origin recognition complex subunit 1 Origin recognition complex subunit 2 Origin recognition complex subunit 3 Origin recognition complex subunit 4 Origin recognition complex subunit 5 Origin recognition complex subunit 6	O43913 O43929 Q13415 Q13416 Q99741 Q9UBD5 Q9UJA3 Q9Y5N6	C20orf154 CDC18L CDC6 LATHEO MCM8 ORC1 ORC1L ORC2 ORC2L ORC3 ORC3L ORC4 ORC4L ORC5 ORC5L ORC6 ORC6L PARC1	Homo sapiens (human)
RUNX1 regulates transcription of genes involved in differentiation of HSCs	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 CDK-activating kinase assembly factor MAT1 Core-binding factor subunit beta Cyclin-H Cyclin-dependent kinase 7 E3 ubiquitin-protein ligase Itchy homolog Endothelial transcription factor GATA-2 Erythroid transcription factor Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Histone-lysine N-methyltransferase 2A LIM domain-binding protein 1 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Rhombotin-1 Rhombotin-2 Runt-related transcription factor 1 T-cell acute lymphocytic leukemia protein 1 Trans-acting T-cell-specific transcription factor GATA-3 Transcription factor 12 Transcription factor E2-alpha Transcription factor PU.1 Transcriptional activator Myb Transcriptional coactivator YAP1 Tumor protein p73 Tyrosine-protein kinase ABL1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O15350 O43242 O60814 O75832 P00519 P04908 P06899 P0C5Y9 P0CG47 P0CG48 P10242 P15923 P15976 P16104 P17542 P17947 P17980 P20618 P20671 P23527 P23769 P23771 P25786 P25787 P25788 P25789 P25791 P25800 P28062 P28065 P28066 P28070 P28072 P28074 P33778 P35998 P40306 P43686 P46937 P48556 P49720 P49721 P50613 P51665 P51946 P51948 P55036 P57053 P58876 P60896 P60900 P61289 P62191 P62195 P62333 P62805 P62807 P62979 P62987 P68431 P84243 Q01196 Q03164 Q06323 Q13200 Q13951 Q14997 Q15008 Q16401 Q16777 Q16778 Q6FI13 Q71DI3 Q71UI9 Q86U70 Q8N257 Q8TAA3 Q92530 Q93077 Q93079 Q96A08 Q96J02 Q99081 Q99436 Q99460 Q99877 Q99878 Q99879 Q99880 Q9BTM1 Q9UL46 Q9UNM6	ABL ABL1 ALL1 AML1 BHLHA17 BHLHB20 BHLHB21 C7orf76 CAK CAK1 CAP35 CBFA2 CBFB CCNH CDK7 CDKN7 CLIM2 CXXC7 DSS1 E2A ERYF1 GATA1 GATA2 GATA3 GF1 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HC2 HC3 HC8 HC9 HEB HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 HRX HSPC HTF4 HTRX IFI5111 ITCH ITF1 JTK7 KIAA0072 KIAA0077 KIAA0107 KMT2A LDB1 LMO1 LMO2 LMP10 LMP2 LMP7 LMPX LMPY MAT1 MB1 MCB1 MECL1 MIP224 MLL MLL1 MNAT1 MO15 MOV34L MSS1 MYB NU P73 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RBTN1 RBTN2 RBTNL1 RHOM1 RHOM2 RING10 RING12 RNF66 RPS27A RUNX1 SCL SEM1 SHFDG1 SHFM1 SPI1 STK1 SUG1 SUG2 TAL1 TBP1 TBP7 TCF12 TCF3 TCL5 TP73 TRAP2 TRX1 TSH2B TTG1 TTG2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 YAP1 YAP65 Z	Homo sapiens (human)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation	6-pyruvoyl tetrahydrobiopterin synthase Calmodulin-1 Dihydrofolate reductase GTP cyclohydrolase 1 feedback regulatory protein GTP cyclohydrolase 1 Heat shock protein HSP 90-alpha Nitric oxide synthase 3 RAC-alpha serine/threonine-protein kinase Sepiapterin reductase cGMP-dependent protein kinase 2	P00374 P07900 P0DP23 P29474 P30047 P30793 P31749 P35270 Q03393 Q13237	AKT1 CALM CALM1 CAM CAM1 DHFR DYT5 GCH GCH1 GCHFR GFRP HSP90A HSP90AA1 HSPC1 HSPCA NOS3 PKB PRKG2 PRKGR2 PTS RAC SPR	Homo sapiens (human)
Bloch pathway	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 7-dehydrocholesterol reductase Delta(24)-sterol reductase Lathosterol oxidase	O75845 Q15125 Q15392 Q9UBM7	D7SR DHCR24 DHCR7 EBP KIAA0018 SC5D SC5DL	Homo sapiens (human)
Drug-mediated inhibition of MET activation	Hepatocyte growth factor receptor Hepatocyte growth factor	P08581 P14210	HGF HPTA MET	Homo sapiens (human)
Cleavage of the damaged purine	Adrenocortical dysplasia protein homolog DNA-3-methyladenine glycosylase Endonuclease 8-like 3 Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1t Histone H4 N-glycosylase/DNA lyase Protection of telomeres protein 1 TERF1-interacting nuclear factor 2 Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2	O15527 O60814 P04908 P06899 P0C5Y9 P16104 P20671 P23527 P29372 P33778 P54274 P57053 P58876 P62805 P62807 Q15554 Q16695 Q16777 Q16778 Q6FI13 Q71UI9 Q8N257 Q8TAT5 Q93077 Q93079 Q96A08 Q96AP0 Q99877 Q99878 Q99879 Q99880 Q9BSI4 Q9BTM1 Q9NUX5 Q9NYB0	AAG ACD ANPG DRIP5 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-4 H3FT H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST3H3 HIST4H4 MID1 MMH MPG MUTM NEIL3 OGG1 OGH1 PIN2 PIP1 POT1 PTOP RAP1 TERF1 TERF2 TERF2IP TIN2 TINF2 TINT1 TPP1 TRBF1 TRBF2 TRF TRF1 TRF2 TSH2B	Homo sapiens (human)
Recruitment of mitotic centrosome proteins and complexes	14-3-3 protein epsilon 14-3-3 protein gamma A-kinase anchor protein 9 Alpha-centractin CDK5 regulatory subunit-associated protein 2 CLIP-associating protein 1 Casein kinase I isoform delta Casein kinase I isoform epsilon Centrin-2 Centriolar coiled-coil protein of 110 kDa Centriole and centriolar satellite protein OFD1 Centriolin Centromere protein J Centrosomal protein 43 Centrosomal protein of 131 kDa Centrosomal protein of 135 kDa Centrosomal protein of 152 kDa Centrosomal protein of 164 kDa Centrosomal protein of 192 kDa Centrosomal protein of 290 kDa Centrosomal protein of 41 kDa Centrosomal protein of 57 kDa Centrosomal protein of 63 kDa Centrosomal protein of 70 kDa Centrosomal protein of 72 kDa Centrosomal protein of 76 kDa Centrosomal protein of 78 kDa Centrosome-associated protein ALMS1 Centrosome-associated protein CEP250 Cyclin-dependent kinase 11A Cyclin-dependent kinase 11B Cyclin-dependent kinase 1 Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoskeleton-associated protein 5 Dynactin subunit 2 Dynactin subunit 3 Dynein light chain 1, cytoplasmic Gamma-tubulin complex component 2 Gamma-tubulin complex component 3 Gamma-tubulin complex component 4 Gamma-tubulin complex component 5 Gamma-tubulin complex component 6 HAUS augmin-like complex subunit 1 HAUS augmin-like complex subunit 2 HAUS augmin-like complex subunit 3 HAUS augmin-like complex subunit 4 HAUS augmin-like complex subunit 5 HAUS augmin-like complex subunit 6 HAUS augmin-like complex subunit 7 HAUS augmin-like complex subunit 8 Heat shock protein HSP 90-alpha Microtubule nucleation factor SSNA1 Microtubule-associated protein RP/EB family member 1 Mitotic-spindle organizing protein 1 Mitotic-spindle organizing protein 2A Mitotic-spindle organizing protein 2B Ninein-like protein Nuclear distribution protein nudE homolog 1 Nucleoside diphosphate kinase homolog 7 Outer dense fiber protein 2 Pericentrin Pericentriolar material 1 protein Platelet-activating factor acetylhydrolase IB subunit beta Protein NEDD1 Protein SFI1 homolog Serine/threonine-protein kinase Nek2 Serine/threonine-protein kinase PLK1 Serine/threonine-protein kinase PLK4 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serologically defined colon cancer antigen 8 Tubulin alpha-1A chain Tubulin alpha-4A chain Tubulin beta chain Tubulin beta-4A chain Tubulin beta-4B chain Tubulin gamma-1 chain Tubulin gamma-2 chain cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase type II-beta regulatory subunit	A8K8P3 O00444 O15078 O43303 O43805 O75665 O75935 O94927 O94986 O95613 O95684 P04350 P06493 P07437 P07900 P17612 P21127 P23258 P30153 P31323 P41208 P43034 P48730 P49674 P51955 P53350 P61163 P61981 P62258 P63167 P68366 P68371 Q08AG7 Q13409 Q13561 Q14008 Q14204 Q15154 Q15691 Q5BJF6 Q5JTW2 Q66GS9 Q68CZ6 Q6NZ67 Q6P582 Q71U36 Q7Z460 Q7Z4H7 Q7Z7A1 Q86SQ7 Q86XR8 Q8NHQ1 Q8NHV4 Q8TAP6 Q8TCU4 Q8TEP8 Q96CS2 Q96CW5 Q96MT8 Q96RT7 Q96RT8 Q96SN8 Q99871 Q99996 Q9BSJ2 Q9BT25 Q9BV73 Q9BYV8 Q9H6D7 Q9HC77 Q9NRH3 Q9NVX0 Q9NXR1 Q9P209 Q9UGJ1 Q9UPN4 Q9UPV0 Q9UQ88 Q9Y2I6 Q9Y5B8	76P ACTR1A AKAP350 AKAP450 AKAP9 ALMS1 AZI1 BBS14 BITE C13orf37 C14orf94 C15orf25 C18orf9 C4orf15 C9orf81 CALT CCCAP CCDC5 CCP110 CDC2 CDC28A CDC2L1 CDC2L2 CDC2L3 CDK1 CDK11 CDK11A CDK11B CDK5RAP2 CDKN1 CEN2 CENPJ CEP1 CEP110 CEP131 CEP135 CEP152 CEP164 CEP192 CEP2 CEP215 CEP250 CEP27 CEP290 CEP4 CEP41 CEP43 CEP57 CEP63 CEP70 CEP72 CEP76 CEP78 CETN2 CKAP5 CLASP1 CNAP1 CNTRL CP110 CPAP CSNK1D CSNK1E CTRN1 CXorf5 DCTN2 DCTN22 DCTN3 DCTN50 DGT6 DHC1 DLC1 DNCH1 DNCI2 DNCIC2 DNCL DNCL1 DNCLC1 DNECL DYHC DYNC1H1 DYNC1I2 DYNLL1 FAM128A FAM128B FAM29A FGFR1OP FOP GCP2 GCP3 GCP4 GCP5 GCP6 HAUS1 HAUS2 HAUS3 HAUS4 HAUS5 HAUS6 HAUS7 HAUS8 HCKID HDLC1 HEIC HICE1 HSP90A HSP90AA1 HSPC1 HSPCA KIAA0092 KIAA0097 KIAA0325 KIAA0328 KIAA0373 KIAA0402 KIAA0419 KIAA0542 KIAA0622 KIAA0635 KIAA0803 KIAA0841 KIAA0912 KIAA0980 KIAA1052 KIAA1118 KIAA1519 KIAA1569 KIAA1574 KIAA1633 KIAA1669 KIAA1899 LAP LIP1 LIS1 MAPRE1 MAST1 MDCR MDS MOZART1 MOZART2A MOZART2B MZT1 MZT2A MZT2B NA14 NDE1 NEDD1 NEK2 NEK2A NINL NLK1 NLP NME7 NPHP10 NPHP15 NPHP6 NUDE ODF2 OFD1 P34CDC2 PAFAH1B1 PAFAHA PCM1 PCNT PCNT2 PITSLREA PITSLREB PK58 PKACA PLK PLK1 PLK4 PPP2R1A PRKACA PRKAR2B SAK SDCCAG8 SFI1 SSNA1 STK18 TSGA14 TSP57 TUBA1 TUBA1A TUBA3 TUBA4A TUBB TUBB2C TUBB4 TUBB4A TUBB4B TUBB5 TUBG TUBG1 TUBG2 TUBGCP2 TUBGCP3 TUBGCP4 TUBGCP5 TUBGCP6 UCHL5IP UIP1 YWHAE YWHAG	Homo sapiens (human)
ERKs are inactivated	Dual specificity protein phosphatase 3 Dual specificity protein phosphatase 4 Dual specificity protein phosphatase 6 Dual specificity protein phosphatase 7 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase 7 Serine/threonine-protein kinase VRK3 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	P27361 P28482 P30153 P30154 P51452 P62714 P67775 Q13115 Q13164 Q14738 Q16828 Q16829 Q8IV63	BMK1 DUSP3 DUSP4 DUSP6 DUSP7 ERK1 ERK2 ERK5 MAPK1 MAPK3 MAPK7 MKP2 MKP3 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D PRKM1 PRKM2 PRKM3 PRKM7 PYST1 PYST2 VH2 VHR VRK3	Homo sapiens (human)
Signaling by CSF1 (M-CSF) in myeloid cells	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 E3 ubiquitin-protein ligase CBL GRB2-associated-binding protein 2 GRB2-associated-binding protein 3 GRB2-related adapter protein 2 GTPase KRas Interleukin-34 Macrophage colony-stimulating factor 1 receptor Macrophage colony-stimulating factor 1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Polyubiquitin-B Polyubiquitin-C Proto-oncogene tyrosine-protein kinase Src SHC-transforming protein 1 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Son of sevenless homolog 1 THO complex subunit 5 homolog Tyrosine-protein kinase Fyn Tyrosine-protein kinase HCK Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00329 O15357 O75791 P01116 P06241 P07333 P07947 P07948 P08631 P09603 P0CG47 P0CG48 P12931 P16885 P22681 P27986 P29353 P40763 P42224 P42336 P42338 P62979 P62987 Q06124 Q07889 Q13769 Q6ZMJ4 Q8WWW8 Q92835 Q9UQC2	APRF C16orf77 C22orf19 CBL CBL2 CSF1 CSF1R FMS FYN GAB2 GAB3 GADS GRAP2 GRB1 GRB2L GRID HCK IL34 INPP5D INPPL1 JTK8 KIAA0571 KIAA0983 KRAS KRAS2 LYN PIK3C1 PIK3CA PIK3CB PIK3CD PIK3R1 PLCG2 PTP2C PTPN11 RASK2 RNF55 RPS27A SHC SHC1 SHCA SHIP SHIP1 SHIP2 SHPTP2 SOS1 SRC SRC1 STAT1 STAT3 THOC5 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 YES YES1	Homo sapiens (human)
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	Apoptosis facilitator Bcl-2-like protein 14 Apoptosis-stimulating of p53 protein 1 Apoptosis-stimulating of p53 protein 2 B-cell lymphoma 6 protein Baculoviral IAP repeat-containing protein 5 Cellular tumor antigen p53 Geranylgeranyl transferase type-2 subunit alpha Geranylgeranyl transferase type-2 subunit beta Protein NDRG1 Quinone oxidoreductase PIG3 Rab proteins geranylgeranyltransferase component A 1 Tumor protein 63 Tumor protein p73 p53 apoptosis effector related to PMP-22	O15350 O15392 P04637 P24386 P41182 P53611 Q13625 Q53FA7 Q92597 Q92696 Q96FX8 Q96KQ4 Q9BZR8 Q9H3D4	API4 ASPP1 ASPP2 BBP BCL2L14 BCL5 BCL6 BCLG BIRC5 CAP43 CHM DRG1 GGTB IAP4 KCP1 KET KIAA0771 KRTCAP1 LAZ3 NDRG1 P53 P63 P73 P73H P73L PERP PIG3 PIGPC1 PPP1R13B RABGGTA RABGGTB REP1 RTP TCD THW TP53 TP53BP2 TP53I3 TP63 TP73 TP73L ZBTB27 ZNF51	Homo sapiens (human)
crizotinib-resistant ALK mutants	ALK tyrosine kinase receptor	Q9UM73	ALK	Homo sapiens (human)

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