GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1376 - 1400** of **2090** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism	GlyTouCan ID
Defective ACTH causes obesity and POMCD	Adrenocorticotropic hormone receptor Pro-opiomelanocortin	P01189 Q01718	ACTHR MC2R POMC	Homo sapiens (human)
Glycoprotein hormones	Choriogonadotropin subunit beta 3 Follitropin subunit beta Glycoprotein hormones alpha chain Inhibin alpha chain Inhibin beta A chain Inhibin beta B chain Inhibin beta C chain Inhibin beta E chain Lutropin subunit beta Thyrotropin subunit beta	P01215 P01222 P01225 P01229 P05111 P08476 P09529 P0DN86 P55103 P58166	CGA CGB CGB3 CGB5 CGB8 FSHB INHA INHBA INHBB INHBC INHBE LHB TSHB	Homo sapiens (human)
Thyroxine biosynthesis	Dual oxidase 1 Dual oxidase 2 Glycoprotein hormones alpha chain Iodotyrosine deiodinase 1 Sodium/iodide cotransporter Thyroid peroxidase Thyrotropin subunit beta	P01215 P01222 P07202 Q6PHW0 Q92911 Q9NRD8 Q9NRD9	C6orf71 CGA DEHAL1 DUOX DUOX1 DUOX2 IYD LNOX1 LNOX2 NIS SLC5A5 THOX1 THOX2 TPO TSHB	Homo sapiens (human)
Mineralocorticoid biosynthesis	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 Cytochrome P450 11B2, mitochondrial Glycoprotein hormones alpha chain Lutropin subunit beta Steroid 21-hydroxylase	P01215 P01229 P08686 P14060 P19099 P26439	3BH CGA CYP11B2 CYP21 CYP21A2 CYP21B HSD3B1 HSD3B2 HSDB3A HSDB3B LHB	Homo sapiens (human)
Signal attenuation	Growth factor receptor-bound protein 10 Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor Insulin Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 SHC-transforming protein 1 Son of sevenless homolog 1	P01308 P06213 P27361 P28482 P29353 P35568 Q07889 Q13322 Q9Y4H2	ERK1 ERK2 GRB10 GRBIR INS INSR IRS1 IRS2 KIAA0207 MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 SHC SHC1 SHCA SOS1	Homo sapiens (human)
IRS activation	Growth factor receptor-bound protein 10 Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor Insulin	P01308 P06213 P35568 Q13322 Q9Y4H2	GRB10 GRBIR INS INSR IRS1 IRS2 KIAA0207	Homo sapiens (human)
Signaling by Insulin receptor	Insulin receptor Insulin	P01308 P06213	INS INSR	Homo sapiens (human)
Gastrin-CREB signalling pathway via PKC and MAPK	Gastrin/cholecystokinin type B receptor Gastrin Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase 7 Ribosomal protein S6 kinase alpha-1 Ribosomal protein S6 kinase alpha-2 Ribosomal protein S6 kinase alpha-3	P01350 P27361 P28482 P32239 P51812 Q13164 Q15349 Q15418	BMK1 CCKBR CCKRB ERK1 ERK2 ERK5 GAS GAST ISPK1 MAPK1 MAPK3 MAPK7 MAPKAPK1A MAPKAPK1B MAPKAPK1C PRKM1 PRKM2 PRKM3 PRKM7 RPS6KA1 RPS6KA2 RPS6KA3 RSK1 RSK2 RSK3	Homo sapiens (human)
Intestinal infectious diseases	Guanylyl cyclase C Heat-stable enterotoxin ST-IA/ST-P Na(+)/H(+) exchange regulatory cofactor NHE-RF4	P01559 P25092 Q86UT5	GUC2C GUCY2C IKEPP NHERF4 PDZD3 PDZK2 STAR sta1	Homo sapiens (human)
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)	Complement receptor type 1 Core-binding factor subunit beta Cytotoxic T-lymphocyte protein 4 Forkhead box protein P3 Interferon gamma Interleukin-2 receptor subunit alpha Interleukin-2 Nuclear factor of activated T-cells, cytoplasmic 2 Runt-related transcription factor 1 Tumor necrosis factor receptor superfamily member 18	P01579 P01589 P16410 P17927 P60568 Q01196 Q13469 Q13951 Q9BZS1 Q9Y5U5	AITR AML1 C3BR CBFA2 CBFB CD152 CR1 CTLA4 FOXP3 GITR IFNG IL2 IL2RA IPEX NFAT1 NFATC2 NFATP RUNX1 TNFRSF18	Homo sapiens (human)
Interleukin-1 processing	Caspase-1 Cathepsin G Gasdermin-D Interleukin-1 alpha Interleukin-1 beta Interleukin-18 Nuclear factor NF-kappa-B p100 subunit Nuclear factor NF-kappa-B p105 subunit Transcription factor p65	P01583 P01584 P08311 P19838 P29466 P57764 Q00653 Q04206 Q14116	CASP1 CTSG DFNA5L GSDMD GSDMDC1 IGIF IL18 IL1A IL1B IL1BC IL1BCE IL1F1 IL1F2 IL1F4 LYT10 NFKB1 NFKB2 NFKB3 RELA	Homo sapiens (human)
CLEC7A/inflammasome pathway	Apoptosis-associated speck-like protein containing a CARD Caspase-8 Interleukin-1 beta Mucosa-associated lymphoid tissue lymphoma translocation protein 1 Nuclear factor NF-kappa-B p105 subunit Transcription factor p65	P01584 P19838 Q04206 Q14790 Q9UDY8 Q9ULZ3	ASC CARD5 CASP8 IL1B IL1F2 MALT1 MCH5 MLT NFKB1 NFKB3 PYCARD RELA TMS1	Homo sapiens (human)
Regulation of gene expression by Hypoxia-inducible Factor	Aryl hydrocarbon receptor nuclear translocator CREB-binding protein Carbonic anhydrase 9 Cbp/p300-interacting transactivator 2 Endothelial PAS domain-containing protein 1 Erythropoietin HIG1 domain family member 1A, mitochondrial Histone acetyltransferase p300 Hypoxia-inducible factor 1-alpha Vascular endothelial growth factor A, long form	P01588 P15692 P27540 Q09472 Q16665 Q16790 Q92793 Q99814 Q99967 Q9Y241	ARNT BHLHE2 BHLHE73 BHLHE78 CA9 CBP CITED2 CREBBP EP300 EPAS1 EPO G250 HIF1A HIF2A HIG1 HIGD1A MN MOP1 MOP2 MRG1 P300 PASD2 PASD8 VEGF VEGFA	Homo sapiens (human)
Interleukin-2 signaling	Cytokine receptor common subunit gamma Interleukin-2 receptor subunit alpha Interleukin-2 receptor subunit beta Interleukin-2 Protein-tyrosine kinase 2-beta SHC-transforming protein 1 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK3 Tyrosine-protein kinase Lck Tyrosine-protein kinase SYK	P01589 P06239 P14784 P23458 P29353 P31785 P42229 P43405 P51692 P52333 P60568 Q14289	FAK2 IL15RB IL2 IL2RA IL2RB IL2RG JAK1 JAK1A JAK1B JAK3 LCK PTK2B PYK2 RAFTK SHC SHC1 SHCA STAT5 STAT5A STAT5B SYK	Homo sapiens (human)
Binding and entry of HIV virion	C-C chemokine receptor type 5 C-X-C chemokine receptor type 4 Envelope glycoprotein gp160 Gag polyprotein Gag-Pol polyprotein Peptidyl-prolyl cis-trans isomerase A Protein Nef Protein Rev Protein Vpr Protein Vpu T-cell surface glycoprotein CD4 Virion infectivity factor	P01730 P04578 P04585 P04591 P04601 P04618 P05919 P51681 P61073 P62937 P69723 P69726	CCR5 CD4 CMKBR5 CXCR4 CYPA PPIA env gag gag-pol nef rev vif vpr vpu	Homo sapiens (human)
Alpha-defensins	Defensin alpha 4 Defensin alpha 5 Defensin-6 Envelope glycoprotein gp160 GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 Neutrophil defensin 1 Neutrophil defensin 3 T-cell surface glycoprotein CD4 Trypsin-2 Trypsin-3	P01730 P04578 P07478 P12838 P35030 P52961 P59665 P59666 Q01523 Q01524	ART1 CD4 DEF1 DEF3 DEF4 DEF5 DEF6 DEFA1 DEFA1B DEFA2 DEFA3 DEFA4 DEFA5 DEFA6 MRS PRSS2 PRSS3 PRSS4 TRY2 TRY3 TRY4 TRYP2 env	Homo sapiens (human)
Other interleukin signaling	Alpha-taxilin Caspase-3 Granulocyte colony-stimulating factor receptor Granulocyte colony-stimulating factor Interferon lambda receptor 1 Interferon lambda-1 Interleukin-10 receptor subunit beta Interleukin-32 Interleukin-34 Macrophage colony-stimulating factor 1 receptor Macrophage colony-stimulating factor 1 Myeloblastin Non-receptor tyrosine-protein kinase TYK2 Pro-interleukin-16 Receptor-type tyrosine-protein phosphatase zeta Synaptosomal-associated protein 25 Syndecan-1 Syntaxin-1A Syntaxin-3 Syntaxin-4 Syntaxin-binding protein 2 T-cell surface glycoprotein CD4 Tyrosine-protein kinase JAK1 Vesicle-associated membrane protein 2	P01730 P07333 P09603 P09919 P18827 P23458 P23471 P24001 P24158 P29597 P40222 P42574 P60880 P63027 Q08334 Q12846 Q13277 Q14005 Q15833 Q16623 Q6ZMJ4 Q8IU54 Q8IU57 Q99062	C16orf77 C17orf33 CASP3 CD4 CPP32 CRFB4 CSF1 CSF1R CSF3 CSF3R D21S58 D21S66 FMS GCSF GCSFR HTPZP2 IFNL1 IFNLR1 IL10RB IL16 IL28RA IL29 IL32 IL34 JAK1 JAK1A JAK1B LICR2 MBN NK4 PRTN3 PTPRZ PTPRZ1 PTPRZ2 PTPZ SDC SDC1 SNAP SNAP25 STX1 STX1A STX3 STX3A STX4 STX4A STXBP2 SYB2 TAIF TXLN TXLNA TYK2 UNC18B VAMP2 ZCYTO21	Homo sapiens (human)
Scavenging by Class A Receptors	Apolipoprotein A-I Apolipoprotein B-100 Apolipoprotein E Calreticulin Collagen alpha-1(I) chain Collagen alpha-1(III) chain Collagen alpha-1(IV) chain Collagen alpha-2(I) chain Collagen alpha-2(IV) chain Collectin-11 Collectin-12 Endoplasmin Ferritin heavy chain Ferritin light chain Macrophage receptor MARCO Macrophage scavenger receptor types I and II Mannan-binding lectin serine protease 1 Scavenger receptor class A member 5 Secretoglobin family 3A member 2	P02452 P02461 P02462 P02647 P02649 P02792 P02794 P04114 P08123 P08572 P14625 P21757 P27797 P48740 Q5KU26 Q6ZMJ2 Q96PL1 Q9BWP8 Q9UEW3	APOA1 APOB APOE CALR CLP1 COL1A1 COL1A2 COL3A1 COL4A1 COL4A2 COLEC11 COLEC12 CRARF CRARF1 CRTC FTH FTH1 FTHL6 FTL GRP94 HSP90B1 HSPC4 MARCO MASP1 MSR1 NSR2 PNSP1 PRSS5 SCARA1 SCARA2 SCARA4 SCARA5 SCGB3A2 SRCL TRA1 UGRP1	Homo sapiens (human)	G27025MB G70323CJ G82576YO
Chylomicron remodeling	Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-IV Apolipoprotein A-V Apolipoprotein B-100 Apolipoprotein C-II Apolipoprotein C-III Apolipoprotein E Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 Lipoprotein lipase	P02647 P02649 P02652 P02655 P02656 P04114 P06727 P06858 Q6Q788 Q8IV16	APC2 APOA1 APOA2 APOA4 APOA5 APOB APOC2 APOC3 APOE GPIHBP1 HBP1 LIPD LPL RAP3	Homo sapiens (human)
Chylomicron assembly	Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-IV Apolipoprotein B-100 Apolipoprotein C-II Apolipoprotein C-III Apolipoprotein E Microsomal triglyceride transfer protein large subunit Protein disulfide-isomerase Small COPII coat GTPase SAR1B	P02647 P02649 P02652 P02655 P02656 P04114 P06727 P07237 P55157 Q9Y6B6	APC2 APOA1 APOA2 APOA4 APOB APOC2 APOC3 APOE ERBA2L MTP MTTP P4HB PDI PDIA1 PO4DB SAR1B SARA2 SARB	Homo sapiens (human)
HDL remodeling	ATP-binding cassette sub-family G member 1 Albumin Apolipoprotein A-I Apolipoprotein C-II Apolipoprotein C-III Apolipoprotein E Cholesteryl ester transfer protein Endothelial lipase Phosphatidylcholine-sterol acyltransferase	P02647 P02649 P02655 P02656 P02768 P04180 P11597 P45844 Q9Y5X9	ABC8 ABCG1 ALB APC2 APOA1 APOC2 APOC3 APOE CETP LCAT LIPG WHT1	Homo sapiens (human)
ABC transporters in lipid homeostasis	ATP-binding cassette sub-family A member 10 ATP-binding cassette sub-family A member 2 ATP-binding cassette sub-family A member 6 ATP-binding cassette sub-family A member 9 ATP-binding cassette sub-family D member 1 ATP-binding cassette sub-family D member 2 ATP-binding cassette sub-family D member 3 ATP-binding cassette sub-family G member 1 ATP-binding cassette sub-family G member 4 ATP-binding cassette sub-family G member 5 ATP-binding cassette sub-family G member 8 Apolipoprotein A-I Cholesterol transporter ABCA5 Glucosylceramide transporter ABCA12 Peroxisomal biogenesis factor 19 Peroxisomal biogenesis factor 3 Phospholipid-transporting ATPase ABCA3 Phospholipid-transporting ATPase ABCA7	P02647 P28288 P33897 P40855 P45844 P56589 Q86UK0 Q8IUA7 Q8IZY2 Q8N139 Q8WWZ4 Q8WWZ7 Q99758 Q9BZC7 Q9H172 Q9H221 Q9H222 Q9UBJ2	ABC12 ABC2 ABC3 ABC8 ABCA10 ABCA12 ABCA2 ABCA3 ABCA5 ABCA6 ABCA7 ABCA9 ABCD1 ABCD2 ABCD3 ABCG1 ABCG4 ABCG5 ABCG8 ALD ALD1 ALDL1 ALDR ALDRP APOA1 HK33 KIAA1062 KIAA1888 PEX19 PEX3 PMP70 PXF PXMP1 WHITE2 WHT1	Homo sapiens (human)
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	Apolipoprotein E Protein DEK Transcription factor AP-2-alpha	P02649 P05549 P35659	AP2TF APOE DEK TFAP2 TFAP2A	Homo sapiens (human)
VLDL assembly	Apolipoprotein B-100 Apolipoprotein C-I Apolipoprotein C-IV Microsomal triglyceride transfer protein large subunit Protein disulfide-isomerase	P02654 P04114 P07237 P55056 P55157	APOB APOC1 APOC4 ERBA2L MTP MTTP P4HB PDI PDIA1 PO4DB	Homo sapiens (human)
VLDL clearance	Apolipoprotein B receptor Apolipoprotein B-100 Apolipoprotein C-I Apolipoprotein C-IV Lipolysis-stimulated lipoprotein receptor Very low-density lipoprotein receptor	P02654 P04114 P55056 P98155 Q0VD83 Q86X29	APOB APOB48R APOBR APOC1 APOC4 ILDR3 LISCH LSR VLDLR	Homo sapiens (human)

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