GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1976 - 2000** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
TGFBR3 PTM regulation	Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Matrix metalloproteinase-14 Matrix metalloproteinase-16 Metalloproteinase inhibitor 1 Metalloproteinase inhibitor 2 Nicastrin Presenilin-1 Presenilin-2 Transforming growth factor beta receptor type 3	P01033 P16035 P49768 P49810 P50281 P51512 Q03167 Q8WW43 Q92542 Q96BI3 Q9NZ42	AD3 AD4 APH1A APH1B C8orf57 CLGI KIAA0253 MMP14 MMP16 MMPX2 NCSTN PEN2 PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 STM2 TGFBR3 TIMP TIMP1 TIMP2	Homo sapiens (human)
MAP2K and MAPK activation	14-3-3 protein beta/alpha Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Beta-arrestin-1 Beta-arrestin-2 Connector enhancer of kinase suppressor of ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase NRas Integrin alpha-IIb Integrin beta-3 Interleukin-17 receptor D Kinase suppressor of Ras 1 Kinase suppressor of Ras 2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Phosphatidylethanolamine-binding protein 1 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A Ras-related protein Rap-1b Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Talin-1 Tyrosine-protein kinase CSK Vinculin WD repeat domain-containing protein 83 von Willebrand factor	P01111 P01112 P02671 P02675 P02679 P02751 P04049 P04275 P05106 P08514 P10398 P12931 P15056 P18206 P27361 P27448 P28482 P30086 P31946 P32121 P36507 P41240 P46940 P49407 P61224 P62834 Q02750 Q6VAB6 Q7Z5R6 Q8IVT5 Q8NFM7 Q8WXI2 Q969H4 Q9BRX9 Q9UHA4 Q9Y2Q5 Q9Y490	APBB1IP ARAF ARAF1 ARB2 ARR1 ARR2 ARRB1 ARRB2 BRAF BRAF1 CNK1 CNK2 CNKSR1 CNKSR2 CSK CTAK1 EMK2 ERK1 ERK2 F8VWF FGA FGB FGG FN FN1 GP2B GP3A HRAS HRAS1 IL17RD IL17RLM IQGAP1 ITGA2B ITGAB ITGB3 KIAA0051 KIAA0902 KIAA1027 KREV1 KSR KSR1 KSR2 LAMTOR2 LAMTOR3 MAP2K1 MAP2K1IP1 MAP2K2 MAPBPIP MAPK1 MAPK3 MAPKSP1 MARK3 MEK1 MEK2 MKK2 MORG1 NRAS PBP PEBP PEBP1 PKS PKS2 PREL1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 RAF RAF1 RAFB1 RAP1A RAP1B RARP1 RIAM ROBLD3 SEF SRC SRC1 TLN TLN1 VCL VWF WDR83 YWHAB	Homo sapiens (human)
ESR-mediated signaling	Estrogen receptor beta Estrogen receptor Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Peptidyl-prolyl cis-trans isomerase D Peptidyl-prolyl cis-trans isomerase FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP5 Prostaglandin E synthase 3 Serine/threonine-protein phosphatase 5	P03372 P07900 P08238 P27361 P28482 P53041 Q02790 Q08752 Q13451 Q15185 Q92731	AIG6 CYP40 CYPD ERK1 ERK2 ESR ESR1 ESR2 ESTRB FKBP4 FKBP5 FKBP51 FKBP52 HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB MAPK1 MAPK3 NR3A1 NR3A2 P23 PPID PPP5 PPP5C PRKM1 PRKM2 PRKM3 PTGES3 TEBP	Homo sapiens (human)
Glucocorticoid biosynthesis	11-beta-hydroxysteroid dehydrogenase 1 11-beta-hydroxysteroid dehydrogenase type 2 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 Corticosteroid-binding globulin Cytochrome P450 11B1, mitochondrial Cytochrome P450 11B2, mitochondrial Pro-opiomelanocortin Steroid 17-alpha-hydroxylase/17,20 lyase Steroid 21-hydroxylase	P01189 P05093 P08185 P08686 P14060 P15538 P19099 P26439 P28845 P80365	3BH CBG CYP11B1 CYP11B2 CYP17 CYP17A1 CYP21 CYP21A2 CYP21B HSD11 HSD11B1 HSD11B2 HSD11K HSD11L HSD3B1 HSD3B2 HSDB3A HSDB3B POMC S11BH S17AH SDR26C1 SDR9C3 SERPINA6	Homo sapiens (human)
Signaling by juxtamembrane domain KIT mutants	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors	Acetylcholine receptor subunit alpha Neuronal acetylcholine receptor subunit alpha-2 Neuronal acetylcholine receptor subunit alpha-3 Neuronal acetylcholine receptor subunit alpha-4 Neuronal acetylcholine receptor subunit alpha-5 Neuronal acetylcholine receptor subunit alpha-6 Neuronal acetylcholine receptor subunit alpha-7 Neuronal acetylcholine receptor subunit alpha-9 Neuronal acetylcholine receptor subunit beta-2 Neuronal acetylcholine receptor subunit beta-3 Neuronal acetylcholine receptor subunit beta-4	P02708 P17787 P30532 P30926 P32297 P36544 P43681 Q05901 Q15822 Q15825 Q9UGM1	ACHRA CHNRA CHRNA1 CHRNA2 CHRNA3 CHRNA4 CHRNA5 CHRNA6 CHRNA7 CHRNA9 CHRNB2 CHRNB3 CHRNB4 NACHRA3 NACHRA5 NACHRA7 NACHRA9 NACRA4	Homo sapiens (human)
LXRs regulate gene expression linked to gluconeogenesis	Nuclear receptor-interacting protein 1 Oxysterols receptor LXR-alpha Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Retinoic acid receptor RXR-alpha Retinoic acid receptor RXR-beta	P19793 P28702 P35558 P48552 Q13133	LXRA NR1H3 NR2B1 NR2B2 NRIP1 PCK1 PEPCK1 RXRA RXRB	Homo sapiens (human)
Activation of AMPA receptors	Glutamate receptor 1 Glutamate receptor 2 Glutamate receptor 3 Glutamate receptor 4	P42261 P42262 P42263 P48058	GLUA1 GLUH1 GLUR1 GLUR2 GLUR3 GLUR4 GLURC GRIA1 GRIA2 GRIA3 GRIA4 GluA2 GluA3 GluA4	Homo sapiens (human)
FCGR3A-mediated phagocytosis	Abl interactor 1 Abl interactor 2 Actin nucleation-promoting factor WAS Actin nucleation-promoting factor WASL Actin, cytoplasmic 1 Actin, cytoplasmic 2 Actin-binding protein WASF1 Actin-binding protein WASF2 Actin-binding protein WASF3 Actin-related protein 2/3 complex subunit 1A Actin-related protein 2/3 complex subunit 1B Actin-related protein 2/3 complex subunit 2 Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2 Actin-related protein 3 Adapter molecule crk BAR/IMD domain-containing adapter protein 2 Cell division control protein 42 homolog Cytoplasmic FMR1-interacting protein 1 Cytoplasmic FMR1-interacting protein 2 Dedicator of cytokinesis protein 1 Engulfment and cell motility protein 1 Engulfment and cell motility protein 2 Focal adhesion kinase 1 Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 IGHV7-81 protein Immunoglobulin heavy constant gamma 1 Immunoglobulin heavy constant gamma 2 Immunoglobulin heavy constant gamma 3 Immunoglobulin heavy constant gamma 4 Immunoglobulin heavy variable 1-2 Immunoglobulin heavy variable 1-46 Immunoglobulin heavy variable 1-69 Immunoglobulin heavy variable 2-5 Immunoglobulin heavy variable 2-70 Immunoglobulin heavy variable 3-11 Immunoglobulin heavy variable 3-13 Immunoglobulin heavy variable 3-23 Immunoglobulin heavy variable 3-30 Immunoglobulin heavy variable 3-33 Immunoglobulin heavy variable 3-48 Immunoglobulin heavy variable 3-53 Immunoglobulin heavy variable 3-7 Immunoglobulin heavy variable 3-9 Immunoglobulin heavy variable 4-34 Immunoglobulin heavy variable 4-39 Immunoglobulin heavy variable 4-59 Immunoglobulin kappa constant Immunoglobulin kappa variable 1-12 Immunoglobulin kappa variable 1-16 Immunoglobulin kappa variable 1-17 Immunoglobulin kappa variable 1-33 Immunoglobulin kappa variable 1-39 Immunoglobulin kappa variable 1-5 Immunoglobulin kappa variable 1D-12 Immunoglobulin kappa variable 1D-16 Immunoglobulin kappa variable 1D-33 Immunoglobulin kappa variable 1D-39 Immunoglobulin kappa variable 2-28 Immunoglobulin kappa variable 2-29 Immunoglobulin kappa variable 2-30 Immunoglobulin kappa variable 2D-28 Immunoglobulin kappa variable 2D-30 Immunoglobulin kappa variable 2D-40 Immunoglobulin kappa variable 3-11 Immunoglobulin kappa variable 3-15 Immunoglobulin kappa variable 3-20 Immunoglobulin kappa variable 3D-20 Immunoglobulin kappa variable 4-1 Immunoglobulin kappa variable 5-2 Immunoglobulin lambda constant 1 Immunoglobulin lambda constant 2 Immunoglobulin lambda constant 3 Immunoglobulin lambda constant 6 Immunoglobulin lambda constant 7 Immunoglobulin lambda variable 1-40 Immunoglobulin lambda variable 1-44 Immunoglobulin lambda variable 1-47 Immunoglobulin lambda variable 1-51 Immunoglobulin lambda variable 2-11 Immunoglobulin lambda variable 2-14 Immunoglobulin lambda variable 2-23 Immunoglobulin lambda variable 2-8 Immunoglobulin lambda variable 3-19 Immunoglobulin lambda variable 3-1 Immunoglobulin lambda variable 3-21 Immunoglobulin lambda variable 3-25 Immunoglobulin lambda variable 3-27 Immunoglobulin lambda variable 6-57 Immunoglobulin lambda variable 7-43 Immunolglobulin kappa light chain variable region L22 (Fragment) Low affinity immunoglobulin gamma Fc region receptor III-A Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Myosin-2 Myosin-9 NCK-interacting protein with SH3 domain Nck-associated protein 1-like Nck-associated protein 1 Protein BRICK1 Proto-oncogene vav Putative GIPL galf transferase Ras-related C3 botulinum toxin substrate 1 SH2/SH3 adapter protein NCK1 T-cell surface glycoprotein CD3 gamma chain Tyrosine-protein kinase ABL1 Tyrosine-protein kinase BTK Tyrosine-protein kinase Fgr Tyrosine-protein kinase Fyn Tyrosine-protein kinase HCK Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Tyrosine-protein kinase Yes UGa8H (Fragment) Unconventional myosin-IXb Unconventional myosin-Ic Unconventional myosin-Va Unconventional myosin-X V1-11 protein (Fragment) V1-13 protein (Fragment) V1-16 protein (Fragment) V1-20 protein (Fragment) V1-3 protein (Fragment) V1-5 protein (Fragment) V1-7 protein (Fragment) V1-9 protein (Fragment) V2-11 protein (Fragment) V2-15 protein (Fragment) V2-17 protein (Fragment) V2-19 protein (Fragment) V2-8 protein (Fragment) V3-2 protein (Fragment) V3-3 protein (Fragment) V3-4 protein (Fragment) V4-1 protein (Fragment) V4-2 protein (Fragment) V4-6 protein (Fragment) V5-1 protein (Fragment) V5-4 protein (Fragment) V5-6 protein (Fragment) WAS/WASL-interacting protein family member 1 WAS/WASL-interacting protein family member 2 WAS/WASL-interacting protein family member 3	A0A075B6P5 A0A075B6S6 A0A0C4DH25 A0A0C4DH73 A0M8Q6 A2KUC3 A2NJV5 A2NXD2 A6NGB9 O00159 O00401 O15143 O15144 O15145 O15511 O43516 P00519 P01593 P01594 P01597 P01599 P01601 P01602 P01611 P01614 P01615 P01619 P01624 P01699 P01700 P01701 P01703 P01704 P01705 P01706 P01709 P01714 P01715 P01717 P01718 P01721 P01742 P01743 P01762 P01763 P01764 P01766 P01767 P01768 P01772 P01780 P01782 P01814 P01817 P01824 P01825 P01834 P01857 P01859 P01860 P01861 P04211 P04430 P04432 P04433 P06241 P06310 P06312 P06315 P06331 P07947 P07948 P08631 P08637 P09693 P09769 P0CF74 P0CG04 P0DOY2 P0DOY3 P15498 P16333 P23083 P27361 P28482 P35579 P42768 P43405 P46108 P52735 P55160 P59998 P60709 P60953 P61158 P61160 P63000 P63261 P80748 Q05397 Q06187 Q13459 Q14185 Q4QD44 Q5NV61 Q5NV62 Q5NV64 Q5NV65 Q5NV66 Q5NV67 Q5NV68 Q5NV69 Q5NV75 Q5NV79 Q5NV80 Q5NV81 Q5NV82 Q5NV83 Q5NV84 Q5NV85 Q5NV86 Q5NV87 Q5NV89 Q5NV90 Q5NV91 Q5NV92 Q6PIL0 Q7L576 Q8IZP0 Q8TF74 Q8WUW1 Q92556 Q92558 Q92747 Q96F07 Q96JJ3 Q9HD67 Q9NYB9 Q9NZQ3 Q9UKW4 Q9UKX2 Q9UPY6 Q9UQB8 Q9Y2A7 Q9Y4I1 Q9Y6W5	ABI1 ABI2 ABL ABL1 ACTB ACTG ACTG1 ACTR2 ACTR3 AF3P21 AGMX1 ARC16 ARC20 ARC21 ARC34 ARC41 ARGBPIA ARP2 ARP3 ARPC1A ARPC1B ARPC2 ARPC3 ARPC4 ARPC5 ATK BAIAP2 BPK BRK1 BTK C3orf10 CD16A CD3G CDC42 CED12A CR16 CRK CYFIP1 CYFIP2 DOCK1 ELMO1 ELMO2 ERK1 ERK2 FAK FAK1 FCG3 FCGR3 FCGR3A FGR FYN HCK HEM1 HEM2 IGFR3 IGHG1 IGHG2 IGHG3 IGHG4 IGHV IGHV1-2 IGHV1-46 IGHV1-69 IGHV2-5 IGHV2-70 IGHV3-11 IGHV3-13 IGHV3-23 IGHV3-30 IGHV3-33 IGHV3-48 IGHV3-53 IGHV3-7 IGHV3-9 IGHV4-34 IGHV4-39 IGHV4-59 IGHV7-81 IGKC IGKV1-12 IGKV1-16 IGKV1-17 IGKV1-33 IGKV1-39 IGKV1-5 IGKV1D-12 IGKV1D-16 IGKV1D-33 IGKV1D-39 IGKV2-28 IGKV2-29 IGKV2-30 IGKV2D-28 IGKV2D-30 IGKV2D-40 IGKV3-11 IGKV3-15 IGKV3-20 IGKV3D-20 IGKV4-1 IGKV5-2 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7 IGLV IGLV1-40 IGLV1-44 IGLV1-47 IGLV1-51 IGLV2-11 IGLV2-14 IGLV2-23 IGLV2-8 IGLV3-1 IGLV3-19 IGLV3-21 IGLV3-25 IGLV3-27 IGLV6-57 IGLV7-43 IMD2 JTK7 JTK8 KIAA0068 KIAA0269 KIAA0281 KIAA0587 KIAA0799 KIAA0900 KIAA1168 KIAA1834 LPG1G LPG1G2 LYN MAPK1 MAPK3 MYH12 MYH2 MYH9 MYHSA2 MYO10 MYO1C MYO5A MYO9B MYR5 NAP1 NCK NCK1 NCKAP1 NCKAP1L NCKIPSD PIR121 PRKM1 PRKM2 PRKM3 PTK2 RAC1 SCAR1 SCAR3 SOP2L SPIN90 SRC2 SSH3BP1 SYK T3G TC25 V1-11 V1-13 V1-16 V1-20 V1-3 V1-5 V1-7 V1-9 V2-11 V2-15 V2-17 V2-19 V2-8 V3-2 V3-3 V3-4 V4-1 V4-2 V4-6 V5-1 V5-4 V5-6 VAV VAV1 VAV2 VAV3 WAS WASF1 WASF2 WASF3 WASL WASPIP WAVE1 WAVE2 WAVE3 WICH WIP WIPF1 WIPF2 WIPF3 WIRE YES YES1	Homo sapiens (human)
Digestion of dietary lipid	Bile salt-activated lipase Colipase Gastric triacylglycerol lipase Inactive pancreatic lipase-related protein 1 Pancreatic lipase-related protein 2 Pancreatic lipase-related protein 3 Pancreatic triacylglycerol lipase	P04118 P07098 P16233 P19835 P54315 P54317 Q17RR3	BAL CEL CLPS LIPF PLRP1 PLRP2 PNLIP PNLIPRP1 PNLIPRP2 PNLIPRP3	Homo sapiens (human)
SUMOylation of nuclear envelope proteins	Ran GTPase-activating protein 1 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1	P46060 P63165 P63279	KIAA1835 RANGAP1 SD SMT3C SMT3H3 SUMO1 UBC9 UBCE9 UBE2I UBL1	Homo sapiens (human)
Cytochrome P450 - arranged by substrate type	NADPH--cytochrome P450 reductase	P16435	CYPOR POR	Homo sapiens (human)
CD28 dependent PI3K/Akt signaling	3-phosphoinositide-dependent protein kinase 1 Acyl-coenzyme A thioesterase THEM4 Membrane protein Mitogen-activated protein kinase kinase kinase 14 Mitogen-activated protein kinase kinase kinase 8 Nucleoprotein Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Proline-rich protein 5 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Rapamycin-insensitive companion of mTOR Serine/threonine-protein kinase mTOR T-cell-specific surface glycoprotein CD28 T-lymphocyte activation antigen CD80 T-lymphocyte activation antigen CD86 Target of rapamycin complex 2 subunit MAPKAP1 Target of rapamycin complex subunit LST8 Tribbles homolog 3 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lck	O00459 O15530 P06239 P06241 P0DTC5 P0DTC9 P10747 P27986 P31749 P31751 P33681 P41279 P42081 P42336 P42345 P85299 Q5T1C6 Q6R327 Q92569 Q96RU7 Q99558 Q9BPZ7 Q9BVC4 Q9Y243	AKT1 AKT2 AKT3 C20orf97 CD28 CD28LG CD28LG1 CD28LG2 CD80 CD86 COT CTMP ESTF FRAP FRAP1 FRAP2 FYN GBL GRB1 KIAA1999 LAB7 LCK LST8 M MAP3K14 MAP3K8 MAPKAP1 MIP1 MLST8 MTOR N NIK NIPK PDK1 PDPK1 PIK3CA PIK3R1 PIK3R2 PIK3R3 PKB PKBG PROTOR1 PRR5 RAC RAFT1 RAPT1 RICTOR SIN1 SKIP3 THEM4 TRB3 TRIB3	Homo sapiens (human)
Axonal growth inhibition (RHOA activation)	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 Myelin-associated glycoprotein Oligodendrocyte-myelin glycoprotein Proto-oncogene DBL Reticulon-4 Rho GDP-dissociation inhibitor 1 Transforming protein RhoA Tumor necrosis factor receptor superfamily member 16	P08138 P10911 P20916 P23515 P52565 P61586 Q96FE5 Q9NQC3	ARH12 ARHA ARHGDIA DBL GDIA1 GMA KIAA0886 LERN1 LINGO1 LRRN6A MAG MCF2 NGFR NOGO OMG OMGP RHO12 RHOA RTN4 TNFRSF16	Homo sapiens (human)
RNA Polymerase III Abortive And Retractive Initiation	DNA-directed RNA polymerase III subunit RPC10 DNA-directed RNA polymerase III subunit RPC1 DNA-directed RNA polymerase III subunit RPC2 DNA-directed RNA polymerase III subunit RPC3 DNA-directed RNA polymerase III subunit RPC4 DNA-directed RNA polymerase III subunit RPC5 DNA-directed RNA polymerase III subunit RPC6 DNA-directed RNA polymerase III subunit RPC7-like DNA-directed RNA polymerase III subunit RPC7 DNA-directed RNA polymerase III subunit RPC8 DNA-directed RNA polymerase III subunit RPC9 DNA-directed RNA polymerases I and III subunit RPAC1 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription factor 3C polypeptide 1 General transcription factor 3C polypeptide 2 General transcription factor 3C polypeptide 3 General transcription factor 3C polypeptide 4 General transcription factor 3C polypeptide 5 General transcription factor 3C polypeptide 6 Lupus La protein Nuclear factor 1 A-type Nuclear factor 1 B-type Nuclear factor 1 C-type Nuclear factor 1 X-type POU domain, class 2, transcription factor 1 Protein POLR1D, isoform 2 TATA-box-binding protein Transcription factor IIIA Transcription factor IIIB 50 kDa subunit Transcription factor IIIB 90 kDa subunit Transcription factor TFIIIB component B'' homolog Zinc finger protein 143 snRNA-activating protein complex subunit 1 snRNA-activating protein complex subunit 2 snRNA-activating protein complex subunit 3 snRNA-activating protein complex subunit 4 snRNA-activating protein complex subunit 5	A6H8Y1 O00712 O14802 O15160 O15318 O75575 O75971 P05423 P05455 P08651 P0DPB5 P14859 P19388 P20226 P52434 P52747 P53803 P61218 P62875 Q12789 Q12857 Q13487 Q14938 Q16533 Q5SXM2 Q8WUA4 Q92664 Q92966 Q92994 Q969F1 Q9BT43 Q9BUI4 Q9H1D9 Q9HAW0 Q9NVU0 Q9NW08 Q9UKN8 Q9Y2Y1 Q9Y535 Q9Y5Q8 Q9Y5Q9	BDP1 BN51 BN51T BRF BRF1 BRF2 BRFU C6orf51 CRCP GTF2D1 GTF3A GTF3B GTF3C1 GTF3C2 GTF3C3 GTF3C4 GTF3C5 GTF3C6 KIAA0011 KIAA1241 KIAA1439 KIAA1452 KIAA1665 KIAA1689 NFI NFIA NFIB NFIC NFIX OCT1 OTF1 POLR1C POLR1D POLR1E POLR2E POLR2F POLR2H POLR2K POLR2L POLR3A POLR3B POLR3C POLR3D POLR3E POLR3F POLR3G POLR3GL POLR3H POLR3K POLRF POU2F1 RPC11 RPC8 SBF SNAP19 SNAP190 SNAP43 SNAP45 SNAP50 SNAPC1 SNAPC2 SNAPC3 SNAPC4 SNAPC5 SSB STAF TAF3B2 TAF3C TBP TF2D TFIID TFNR ZNF143	Homo sapiens (human)
PI-3K cascade:FGFR1	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 GRB2-associated-binding protein 1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Tyrosine-protein phosphatase non-receptor type 11	O15520 P05230 P08620 P09038 P10767 P11487 P27986 P31371 P42336 Q06124 Q13480 Q8WU20 Q9GZV9 Q9HCT0 Q9NP95	FGF1 FGF10 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF9 FGFA FGFB FRS2 GAB1 GRB1 HST HST2 HSTF1 HSTF2 HYPF INT2 KS3 PIK3CA PIK3R1 PTP2C PTPN11 SHPTP2	Homo sapiens (human)
Autodegradation of Cdh1 by Cdh1:APC/C	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Fizzy-related protein homolog Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O00762 O14818 O43242 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P30260 P35998 P43686 P48556 P49720 P49721 P51665 P51668 P51965 P60006 P60896 P60900 P62191 P62195 P62333 P62979 P62987 Q13042 Q13200 Q15008 Q16186 Q16763 Q8NHZ8 Q96DE5 Q99436 Q99460 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM11 Q9UM13 Q9UNM6	ADRM1 ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 C10orf104 C11orf51 C7orf76 C9orf17 CDC16 CDC23 CDC26 CDC27 CDH1 CENP-27 D0S1430E D17S978E DSS1 E2EPF FYR FZR FZR1 GP110 HC2 HC3 HC8 HC9 HSPC KIAA0107 KIAA1242 KIAA1406 LMPX LMPY MB1 MIP224 MOV34L MSS1 NU PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RPS27A SEM1 SFT SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 TSG24 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S X Y Z	Homo sapiens (human)
Rev-mediated nuclear export of HIV RNA	Aladin E3 SUMO-protein ligase RanBP2 Exportin-1 GTP-binding nuclear protein Ran Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Protein Rev Protein SEC13 homolog Ran GTPase-activating protein 1 Ran-specific GTPase-activating protein Regulator of chromosome condensation mRNA export factor RAE1	A8CG34 O14980 O15504 O75694 P04618 P12270 P18754 P35658 P37198 P43487 P46060 P49790 P49792 P55735 P57740 P62826 P78406 Q12769 Q5SRE5 Q7Z3B4 Q8N1F7 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q96HA1 Q99567 Q9BTX1 Q9BW27 Q9NRG9 Q9UKX7	AAAS ADRACALA ARA24 C7orf14 CAIN CAN CG1 CHC1 CRM1 D3S1231E KIAA0023 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 KIAA1835 MP44 MRNP41 NDC1 NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PCNT1 POM121 POM121A POM121C RAE1 RAN RANBP1 RANBP2 RANGAP1 RCC1 SD SEC13 SEC13A SEC13L1 SEC13R TMEM48 TPR XPO1 rev	Homo sapiens (human)
SDK interactions	Protein sidekick-1 Protein sidekick-2	Q58EX2 Q7Z5N4	KIAA1514 SDK1 SDK2	Homo sapiens (human)
Beta oxidation of butanoyl-CoA to acetyl-CoA	Acyl-coenzyme A synthetase ACSM3, mitochondrial Acyl-coenzyme A synthetase ACSM6, mitochondrial Enoyl-CoA hydratase, mitochondrial Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial Short-chain specific acyl-CoA dehydrogenase, mitochondrial	P16219 P30084 Q16836 Q53FZ2 Q6P461	ACADS ACSM3 ACSM6 C10orf129 ECHS1 HAD HAD1 HADH HADHSC SAH SCHAD	Homo sapiens (human)
activated TAK1 mediates p38 MAPK activation	Dual specificity mitogen-activated protein kinase kinase 3 Dual specificity mitogen-activated protein kinase kinase 6 Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase-like 2 MAP kinase-activated protein kinase 2 MAP kinase-activated protein kinase 3 Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 14 Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator Nucleotide-binding oligomerization domain-containing protein 1 Nucleotide-binding oligomerization domain-containing protein 2 Receptor-interacting serine/threonine-protein kinase 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 6 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1	O43187 O43318 O43353 P46734 P49137 P51617 P52564 P61088 Q13404 Q15750 Q15759 Q16539 Q16644 Q8N5C8 Q9HC29 Q9NYJ8 Q9Y239 Q9Y4K3 Q9Y6K9	BLU CARD15 CARD4 CARDIAK CROC1 CSBP CSBP1 CSBP2 CSPB1 FIP3 IKBKG IRAK IRAK1 IRAK2 KIAA0733 MAP2K3 MAP2K6 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MAPK11 MAPK14 MAPKAPK2 MAPKAPK3 MEK3 MEK6 MKK3 MKK6 MXI2 NEMO NOD1 NOD2 PRKM11 PRKMK3 PRKMK6 RICK RIP2 RIPK2 RNF85 SAPK2 SAPK2A SAPK2B SKK2 SKK3 TAB1 TAB2 TAB3 TAK1 TRAF6 UBE2N UBE2V UBE2V1 UEV1	Homo sapiens (human)
PLC-gamma1 signalling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Beta-nerve growth factor High affinity nerve growth factor receptor	P01138 P04629 P19174	MTC NGF NGFB NTRK1 PLC1 PLCG1 TRK TRKA	Homo sapiens (human)
Effects of PIP2 hydrolysis	Diacylglycerol kinase alpha Diacylglycerol kinase beta Diacylglycerol kinase delta Diacylglycerol kinase epsilon Diacylglycerol kinase eta Diacylglycerol kinase gamma Diacylglycerol kinase iota Diacylglycerol kinase kappa Diacylglycerol kinase theta Diacylglycerol kinase zeta Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3 Protein kinase C delta type Protein kinase C epsilon type Protein kinase C eta type Protein kinase C theta type RAS guanyl-releasing protein 1 RAS guanyl-releasing protein 2 Short transient receptor potential channel 3 Short transient receptor potential channel 6 Short transient receptor potential channel 7	O75912 O95267 P23743 P24723 P49619 P52429 P52824 Q02156 Q04759 Q05655 Q13507 Q13574 Q14571 Q14573 Q14643 Q16760 Q5KSL6 Q7LDG7 Q86XP1 Q9HCX4 Q9Y210 Q9Y6T7	CDC25L DAGK DAGK1 DAGK2 DAGK3 DAGK4 DAGK5 DAGK6 DGKA DGKB DGKD DGKE DGKG DGKH DGKI DGKK DGKQ DGKZ INSP3R1 ITPR1 ITPR2 ITPR3 KIAA0145 KIAA0718 MCG7 PKCD PKCE PKCL PRKCD PRKCE PRKCH PRKCL PRKCQ PRKCT RASGRP RASGRP1 RASGRP2 TRP3 TRP6 TRP7 TRPC3 TRPC6 TRPC7	Homo sapiens (human)
SARS-CoV-1-host interactions	Heterogeneous nuclear ribonucleoprotein A1 Nucleophosmin Nucleoprotein	P06748 P09651 P59595	HNRNPA1 HNRPA1 N NPM NPM1	Homo sapiens (human)
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7	Inhibitor of nuclear factor kappa-B kinase subunit epsilon Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Optineurin Polyubiquitin-B Polyubiquitin-C Serine/threonine-protein kinase TBK1 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 TNF receptor-associated factor 3 TRAF family member-associated NF-kappa-B activator Toll-like receptor 4 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00206 P08571 P0CG47 P0CG48 P62979 P62987 Q13114 Q14164 Q86XR7 Q8IUC6 Q92844 Q96CV9 Q9UHD2 Q9Y6Y9	CAP-1 CD14 CRAF1 ESOP1 FIP2 GLC1E HIP7 HYPL IKBKE IKKE IKKI ITRAF KIAA0151 LY96 MD2 NAK NRP OPTN PRVTIRB RPS27A TANK TBK1 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAF2 TRAF3 TRAFAMN TRAM TRIF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)

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