GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **226 - 250** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol
Integrin cell surface interactions	Agrin Basement membrane-specific heparan sulfate proteoglycan core protein Basigin CD44 antigen Cadherin-1 Cartilage oligomeric matrix protein Collagen alpha-1(IV) chain Collagen alpha-1(IX) chain Collagen alpha-1(XIII) chain Collagen alpha-1(XVI) chain Collagen alpha-1(XVIII) chain Collagen alpha-1(XXIII) chain Collagen alpha-2(IV) chain Collagen alpha-2(IX) chain Collagen alpha-3(IV) chain Collagen alpha-3(IX) chain Collagen alpha-4(IV) chain Fibrillin-1 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin Integrin alpha-10 Integrin alpha-11 Integrin alpha-1 Integrin alpha-2 Integrin alpha-3 Integrin alpha-4 Integrin alpha-5 Integrin alpha-6 Integrin alpha-7 Integrin alpha-8 Integrin alpha-9 Integrin alpha-D Integrin alpha-E Integrin alpha-IIb Integrin alpha-L Integrin alpha-M Integrin alpha-V Integrin alpha-X Integrin beta-1 Integrin beta-2 Integrin beta-3 Integrin beta-5 Integrin beta-6 Integrin beta-7 Integrin beta-8 Integrin-binding sialoprotein Intercellular adhesion molecule 1 Intercellular adhesion molecule 2 Intercellular adhesion molecule 3 Intercellular adhesion molecule 4 Intercellular adhesion molecule 5 Junctional adhesion molecule A Junctional adhesion molecule B Junctional adhesion molecule C Leukocyte surface antigen CD47 Lumican Osteopontin Platelet endothelial cell adhesion molecule Tenascin Thrombospondin-1 Vascular cell adhesion protein 1 Vascular endothelial growth factor receptor 2 Vitronectin	O00468 O75578 P02462 P02671 P02675 P02679 P02751 P04004 P05106 P05107 P05362 P05556 P06756 P07996 P08514 P08572 P08648 P10451 P11215 P12830 P13598 P13612 P16070 P16284 P17301 P18084 P18564 P19320 P20701 P20702 P20849 P21815 P23229 P24821 P26006 P26010 P26012 P32942 P35555 P35613 P35968 P38570 P39060 P49747 P51884 P53420 P53708 P56199 P57087 P98160 Q01955 Q07092 Q08722 Q13349 Q13683 Q13797 Q14050 Q14055 Q14773 Q5TAT6 Q86Y22 Q9BX67 Q9UKX5 Q9UMF0 Q9Y624	AGRIN AGRN BNSP BSG C21orf43 CD11A CD11B CD11C CD18 CD44 CD47 CD49B CD49D CDH1 CDHE COL13A1 COL16A1 COL18A1 COL23A1 COL4A1 COL4A2 COL4A3 COL4A4 COL9A1 COL9A2 COL9A3 COMP CR3A F11R FBN FBN1 FGA FGB FGG FLK1 FN FN1 FNRA FNRB GP2B GP3A HSPG2 HXB IBSP ICAM1 ICAM2 ICAM3 ICAM4 ICAM5 ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAB ITGAD ITGAE ITGAL ITGAM ITGAV ITGAX ITGB1 ITGB2 ITGB3 ITGB5 ITGB6 ITGB7 ITGB8 JAM1 JAM2 JAM3 JCAM KDR LDC LHR LUM LW MDF2 MDU2 MDU3 MER6 MFI7 MIC4 MSK12 MSK18 MSK8 OPN PECAM1 SLRR2D SPP1 THBS1 TLCN TLN TNC TSP TSP1 UVO VCAM1 VEGFR2 VEJAM VNRA VTN VTNR
Azathioprine ADME	ATP-binding cassette sub-family C member 4 ATP-binding cassette sub-family C member 5 Equilibrative nucleoside transporter 1 Equilibrative nucleoside transporter 2 GMP synthase [glutamine-hydrolyzing] Glutathione S-transferase A1 Glutathione S-transferase A2 Glutathione S-transferase Mu 1 Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Guanylate kinase Hypoxanthine-guanine phosphoribosyltransferase Inosine-5'-monophosphate dehydrogenase 1 Inosine-5'-monophosphate dehydrogenase 2 Nucleoside diphosphate kinase A Nucleoside diphosphate kinase B Nucleotide triphosphate diphosphatase NUDT15 Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Sodium/nucleoside cotransporter 2 Solute carrier family 28 member 3 Thiopurine S-methyltransferase Xanthine dehydrogenase/oxidase	O15439 O15440 O43868 P00492 P08263 P09210 P09488 P12268 P15498 P15531 P20839 P22392 P47989 P49915 P51580 P52735 P63000 Q14542 Q16774 Q99808 Q9HAS3 Q9NV35 Q9UKW4	ABCC4 ABCC5 CNT2 CNT3 DER12 ENT1 ENT2 GMK GMPK GMPS GST1 GST2 GSTA1 GSTA2 GSTM1 GUK1 HNP36 HPRT HPRT1 IMPD1 IMPD2 IMPDH1 IMPDH2 MOATB MRP4 MRP5 MTH2 NDPKA NM23 NM23B NME1 NME2 NUDT15 RAC1 SLC28A2 SLC28A3 SLC29A1 SLC29A2 TC25 TPMT VAV VAV1 VAV2 VAV3 XDH XDHA
Signaling by BMP	Activin receptor type-2A Activin receptor type-2B Anti-Muellerian hormone type-2 receptor Bone morphogenetic protein 10 Bone morphogenetic protein 2 Bone morphogenetic protein receptor type-1A Bone morphogenetic protein receptor type-1B Bone morphogenetic protein receptor type-2 Cerberus Chordin-like protein 1 E3 ubiquitin-protein ligase SMURF1 E3 ubiquitin-protein ligase SMURF2 Follistatin-related protein 1 Gremlin-2 Growth/differentiation factor 2 Inhibin alpha chain Inhibin beta A chain Mothers against decapentaplegic homolog 1 Mothers against decapentaplegic homolog 4 Mothers against decapentaplegic homolog 5 Mothers against decapentaplegic homolog 6 Mothers against decapentaplegic homolog 7 Mothers against decapentaplegic homolog 9 Muellerian-inhibiting factor Noggin Serine/threonine-protein kinase receptor R3 Ski oncogene Transforming growth factor beta receptor type 3 Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D3 Zinc finger FYVE domain-containing protein 16	O00238 O15105 O15198 O43541 O95393 O95813 P03971 P05111 P08476 P12643 P12755 P27037 P36894 P37023 P51668 P61077 Q03167 Q12841 Q13253 Q13485 Q13705 Q13873 Q15797 Q16671 Q7Z3T8 Q99717 Q9BU40 Q9H772 Q9HAU4 Q9HCE7 Q9UK05	ACVR2 ACVR2A ACVR2B ACVRL1 ACVRLK1 ACVRLK3 ALK1 ALK3 AMH AMHR AMHR2 BMP10 BMP2 BMP2A BMP9 BMPR1A BMPR1B BMPR2 BSP1 CER1 CHRDL1 CKTSF1B2 DAND3 DAND4 DPC4 FRP FSTL1 GDF2 GREM2 INHA INHBA KIAA0305 KIAA1625 MADH1 MADH4 MADH5 MADH6 MADH7 MADH8 MADH9 MADR1 MIF MISR2 NOG NRLN1 PPH1 PRDC SFT SKI SMAD1 SMAD4 SMAD5 SMAD6 SMAD7 SMAD8 SMAD9 SMURF1 SMURF2 TGFBR3 UBC5A UBC5C UBCH5 UBCH5A UBCH5C UBE2D1 UBE2D3 ZFYVE16
Scavenging by Class B Receptors	Apolipoprotein A-I Apolipoprotein B-100 Platelet glycoprotein 4 Serum amyloid A-1 protein Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D	A1L4H1 P02647 P04114 P0DJI8 P16671	APOA1 APOB CD36 GP3B GP4 SAA1 SSC5D
Glycerophospholipid catabolism	Glycerophosphocholine cholinephosphodiesterase ENPP6 Glycerophosphodiester phosphodiesterase 1 Glycerophosphodiester phosphodiesterase domain-containing protein 5 Lysophospholipase D GDPD1 Lysophospholipase D GDPD3 Patatin-like phospholipase domain-containing protein 6 Patatin-like phospholipase domain-containing protein 7	Q6UWR7 Q6ZV29 Q7L5L3 Q8IY17 Q8N9F7 Q8WTR4 Q9NZC3	C9orf111 ENPP6 GDE1 GDE2 GDE4 GDE7 GDPD1 GDPD3 GDPD5 MIR16 NTE PNPLA6 PNPLA7
Creatine metabolism	Creatine kinase B-type Creatine kinase M-type Creatine kinase S-type, mitochondrial Creatine kinase U-type, mitochondrial Glycine amidinotransferase, mitochondrial Guanidinoacetate N-methyltransferase Sodium- and chloride-dependent GABA transporter 3 Sodium- and chloride-dependent betaine transporter Sodium- and chloride-dependent creatine transporter 1 Sodium-dependent proline transporter	P06732 P12277 P12532 P17540 P48029 P48065 P48066 P50440 Q14353 Q99884	AGAT BGT1 CKB CKBB CKM CKMM CKMT CKMT1A CKMT1B CKMT2 GABT3 GAMT GAT3 GATM PROT SLC6A11 SLC6A12 SLC6A7 SLC6A8
SMAD4 MH2 Domain Mutants in Cancer	Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4	P84022 Q13485 Q15796	DPC4 MADH2 MADH3 MADH4 MADR2 SMAD2 SMAD3 SMAD4
Impaired BRCA2 translocation to the nucleus	26S proteasome complex subunit SEM1 Breast cancer type 2 susceptibility protein	P51587 P60896	BRCA2 C7orf76 DSS1 FACD FANCD1 SEM1 SHFDG1 SHFM1
LXRs regulate gene expression linked to gluconeogenesis	Nuclear receptor-interacting protein 1 Oxysterols receptor LXR-alpha Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Retinoic acid receptor RXR-alpha Retinoic acid receptor RXR-beta	P19793 P28702 P35558 P48552 Q13133	LXRA NR1H3 NR2B1 NR2B2 NRIP1 PCK1 PEPCK1 RXRA RXRB
Defective gamma-carboxylation of F9	Coagulation factor IX Vitamin K-dependent gamma-carboxylase	P00740 P38435	F9 GC GGCX
Enzymatic degradation of dopamine by COMT	Amine oxidase [flavin-containing] A Catechol O-methyltransferase Transmembrane O-methyltransferase	P21397 P21964 Q8WZ04	COMT COMT2 LRTOMT MAOA TOMT
MAPK1 (ERK2) activation	Dual specificity mitogen-activated protein kinase kinase 2 Interleukin-6 receptor subunit alpha Interleukin-6 Mitogen-activated protein kinase 1 Non-receptor tyrosine-protein kinase TYK2 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein phosphatase non-receptor type 11	O60674 P05231 P08887 P23458 P28482 P29597 P36507 Q06124	ERK2 IFNB2 IL6 IL6R JAK1 JAK1A JAK1B JAK2 MAP2K2 MAPK1 MEK2 MKK2 PRKM1 PRKM2 PRKMK2 PTP2C PTPN11 SHPTP2 TYK2
Recycling of bile acids and salts	ATP-binding cassette sub-family C member 3 Albumin Bile acid receptor Bile acid-CoA Bile salt export pump Gastrotropin Hepatic sodium/bile acid cotransporter Ileal sodium/bile acid cotransporter Long-chain fatty acid transport protein 5 Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Organic solute transporter subunit alpha Organic solute transporter subunit beta Retinoic acid receptor RXR-alpha Solute carrier organic anion transporter family member 1A2 Solute carrier organic anion transporter family member 1B1 Solute carrier organic anion transporter family member 1B3 StAR-related lipid transfer protein 5	O15438 O95342 P02768 P19793 P46721 P51161 Q12908 Q14032 Q14973 Q15596 Q15788 Q86UW1 Q86UW2 Q96RI1 Q9NPD5 Q9NSY2 Q9Y2P5 Q9Y6L6	ABCB11 ABCC3 ACSB ACSVL6 ALB ASBT BAAT BAR BHLHE74 BHLHE75 BSEP CMOAT2 FABP6 FACVL3 FATP5 FXR HRR1 ILBP ILLBP ISBT LST1 LST2 MLP2 MRP3 NCOA1 NCOA2 NR1H4 NR2B1 NTCP NTCP2 OATP OATP1 OATP1A2 OATP1B1 OATP1B3 OATP2 OATP8 OATPC OSTA OSTB RIP14 RXRA SLC10A1 SLC10A2 SLC21A3 SLC21A6 SLC21A8 SLC27A5 SLC51A SLC51B SLCO1A2 SLCO1B1 SLCO1B3 SRC1 SRC2 STARD5 TIF2
RNA Polymerase II Transcription Termination	ATP-dependent RNA helicase DDX39A Chromatin target of PRMT1 protein Cleavage and polyadenylation specificity factor subunit 1 Cleavage and polyadenylation specificity factor subunit 2 Cleavage and polyadenylation specificity factor subunit 3 Cleavage and polyadenylation specificity factor subunit 4 Cleavage and polyadenylation specificity factor subunit 5 Cleavage and polyadenylation specificity factor subunit 7 Cleavage stimulation factor subunit 1 Cleavage stimulation factor subunit 2 tau variant Cleavage stimulation factor subunit 2 Cleavage stimulation factor subunit 3 Eukaryotic initiation factor 4A-III Histone RNA hairpin-binding protein Leucine zipper protein 4 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Poly(A) polymerase alpha Polyadenylate-binding protein 2 Polymerase delta-interacting protein 3 Polyribonucleotide 5'-hydroxyl-kinase Clp1 Pre-mRNA 3'-end-processing factor FIP1 Pre-mRNA cleavage complex 2 protein Pcf11 Pre-mRNA-processing factor 17 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 Pre-mRNA-splicing factor SLU7 Protein CASC3 Protein mago nashi homolog 2 Protein mago nashi homolog RNA-binding protein 8A RNA-binding protein with serine-rich domain 1 Regulator of nonsense transcripts 3B SAP domain-containing ribonucleoprotein Serine/arginine repetitive matrix protein 1 Serine/arginine-rich splicing factor 11 Serine/arginine-rich splicing factor 1 Serine/arginine-rich splicing factor 2 Serine/arginine-rich splicing factor 3 Serine/arginine-rich splicing factor 4 Serine/arginine-rich splicing factor 5 Serine/arginine-rich splicing factor 6 Serine/arginine-rich splicing factor 7 Serine/arginine-rich splicing factor 9 Small nuclear ribonucleoprotein E Small nuclear ribonucleoprotein F Small nuclear ribonucleoprotein G Small nuclear ribonucleoprotein Sm D3 Small nuclear ribonucleoprotein-associated proteins B and B' Spliceosome RNA helicase DDX39B Splicing factor U2AF 26 kDa subunit Splicing factor U2AF 35 kDa subunit Splicing factor U2AF 65 kDa subunit Symplekin THO complex subunit 1 THO complex subunit 2 THO complex subunit 3 THO complex subunit 4 THO complex subunit 5 homolog THO complex subunit 6 homolog THO complex subunit 7 homolog U7 snRNA-associated Sm-like protein LSm10 U7 snRNA-associated Sm-like protein LSm11 UAP56-interacting factor Zinc finger CCCH domain-containing protein 11A Zinc finger protein 473 pre-mRNA 3' end processing protein WDR33	O00148 O15234 O43809 O60508 O75152 O94913 O95391 O95639 P14678 P26368 P33240 P38919 P51003 P52298 P61326 P62304 P62306 P62308 P62318 P82979 P83369 P84103 Q01081 Q01130 Q05048 Q05519 Q07955 Q08170 Q09161 Q10570 Q12996 Q13242 Q13243 Q13247 Q13769 Q13838 Q14493 Q15287 Q16629 Q6I9Y2 Q6UN15 Q86U42 Q86V81 Q86W42 Q8IYB3 Q8N684 Q8NI27 Q8WTR7 Q8WU68 Q92620 Q92797 Q92989 Q969L4 Q96A72 Q96FV9 Q96J01 Q96QD9 Q9BY77 Q9BZI7 Q9C0J8 Q9H0L4 Q9P127 Q9P2I0 Q9UKF6 Q9Y3Y2 Q9Y5S9	ALY ALYREF ASF BAT1 BEF C1orf77 C22orf19 CASC3 CBP20 CBP80 CDC40 CFIM25 CHTOP CLP1 COD CPSF1 CPSF100 CPSF160 CPSF2 CPSF25 CPSF3 CPSF30 CPSF4 CPSF5 CPSF7 CPSF73 CSTF1 CSTF2 CSTF2T CSTF3 CXorf3 DDX38 DDX39 DDX39A DDX39B DDX48 DHX38 EHB3 EIF4A3 FIP1 FIP1L1 FOP FYTTD1 HBP HCC1 HEAB HPR1 HRS KIAA0111 KIAA0224 KIAA0663 KIAA0689 KIAA0824 KIAA0983 KIAA1141 KIAA1367 KIAA1649 LDC2 LSM10 LSM11 LUZP4 MAGOH MAGOH2 MAGOHA MAGOHB MLN51 NAR NCBP NCBP1 NCBP2 NEB1 NIF3L1BP1 NUDT21 PAB2 PABP2 PABPN1 PAP PAPOLA PBSCF PBSCG PCF11 PDIP46 POLDIP3 PRP16 PRP17 PRPF17 RBM8 RBM8A RENT3B RHE RNPS1 SARNP SF2 SF2P33 SFRS1 SFRS11 SFRS2 SFRS3 SFRS4 SFRS5 SFRS6 SFRS7 SFRS9 SLBP SLU7 SNRPB SNRPB1 SNRPD3 SNRPE SNRPF SNRPG SPK SRM160 SRP20 SRP30C SRP40 SRP55 SRP75 SRRM1 SRSF1 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF9 SYMPK THOC1 THOC2 THOC3 THOC4 THOC5 THOC6 THOC7 U2AF1 U2AF1-RS3 U2AF1L3 U2AF1L4 U2AF2 U2AF35 U2AF65 U2AFBP UAP56 UIF UPF3B UPF3X WDC146 WDR33 WDR58 ZC3H11A ZC3HDC11A ZFP100 ZNF473
Impaired BRCA2 binding to PALB2	BRCA1-associated RING domain protein 1 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Breast cancer type 2 susceptibility protein DNA endonuclease RBBP8 DNA repair protein RAD50 DNA repair protein RAD51 homolog 1 DNA repair protein RAD51 homolog 2 DNA repair protein RAD51 homolog 3 DNA repair protein RAD51 homolog 4 DNA repair protein XRCC2 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 Exonuclease 1 Fanconi anemia group J protein Histone acetyltransferase KAT5 Nibrin Partner and localizer of BRCA2 RAD51-associated protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Serine-protein kinase ATM	O15315 O43502 O43543 O60934 O75771 P38398 P49959 P51530 P51587 P54132 Q06609 Q13315 Q13472 Q14191 Q86YC2 Q92878 Q92993 Q96B01 Q96E14 Q99708 Q99728 Q9BX63 Q9H9A7 Q9UQ84	ATM BACH1 BARD1 BLM BRCA1 BRCA2 BRIP1 C16orf75 C9orf76 CTIP DNA2 DNA2L EXO1 EXOI FACD FANCD1 FANCJ FANCN HEX1 HNGS1 HTATIP KAT5 KIAA0083 MRE11 MRE11A NBN NBS NBS1 P95 PALB2 PIR51 RAD50 RAD51 RAD51A RAD51AP1 RAD51B RAD51C RAD51D RAD51L1 RAD51L2 RAD51L3 RBBP8 REC2 RECA RECQ2 RECQ3 RECQL2 RECQL3 RMI1 RMI2 RNF53 TIP60 TOP3 TOP3A WRN XRCC2
Signal regulatory protein family interactions	FYN-binding protein 1 Focal adhesion kinase 1 Leukocyte surface antigen CD47 Protein-tyrosine kinase 2-beta Signal-regulatory protein beta-1 Signal-regulatory protein gamma Src kinase-associated phosphoprotein 2 TYRO protein tyrosine kinase-binding protein Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6 Tyrosine-protein phosphatase non-receptor type substrate 1	O00241 O15117 O43914 O75563 P29350 P78324 Q05397 Q06124 Q08722 Q14289 Q9P1W8	BIT CD47 DAP12 FAK FAK1 FAK2 FYB FYB1 HCP KARAP MER6 MFR MYD1 PRAP PTK2 PTK2B PTP1C PTP2C PTPN11 PTPN6 PTPNS1 PYK2 RA70 RAFTK SAPS SCAP2 SHPS1 SHPTP2 SIRP SIRPA SIRPB1 SIRPB2 SIRPG SKAP2 SKAP55R SLAP130 TYROBP
Ephrin signaling	ARF GTPase-activating protein GIT1 Cytoplasmic protein NCK2 Ephrin type-B receptor 1 Ephrin type-B receptor 2 Ephrin type-B receptor 3 Ephrin type-B receptor 4 Ephrin type-B receptor 6 Ephrin-B1 Ephrin-B2 Ephrin-B3 Myosin regulatory light chain 12A Ras-related C3 botulinum toxin substrate 1 Rho guanine nucleotide exchange factor 7 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Syntenin-1 Tyrosine-protein kinase Fyn	O00560 O15197 O43639 O75914 P06241 P19105 P29323 P52799 P54753 P54760 P54762 P63000 P98172 Q13153 Q13177 Q14155 Q15768 Q9Y2X7	ARHGEF7 COOL1 DRT EFL3 EFNB1 EFNB2 EFNB3 ELK EPHB1 EPHB2 EPHB3 EPHB4 EPHB6 EPHT2 EPHT3 EPLG2 EPLG5 EPLG8 EPTH3 ERK ETK2 FYN GIT1 GRB4 HEK2 HEK5 HEK6 HTK HTKL KIAA0142 LERK2 LERK5 LERK8 MDA9 MLCB MRLC3 MYK1 MYL12A NCK2 NET OPHN3 P85SPR PAK1 PAK2 PAK3 PAK3BP PIXB RAC1 RLC SDCBP SYCL TC25 TYRO11 TYRO5 TYRO6
Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM)	Sodium-dependent phosphate transport protein 2B	O95436	SLC34A2
RNA Polymerase II Transcription Initiation And Promoter Clearance	CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-dependent kinase 7 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIE subunit 1 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 TATA-binding protein-associated factor 2N TATA-box-binding protein Transcription initiation factor IIA subunit 1 Transcription initiation factor IIA subunit 2 Transcription initiation factor IIB Transcription initiation factor IIE subunit beta Transcription initiation factor TFIID subunit 1-like Transcription initiation factor TFIID subunit 10 Transcription initiation factor TFIID subunit 11 Transcription initiation factor TFIID subunit 12 Transcription initiation factor TFIID subunit 13 Transcription initiation factor TFIID subunit 1 Transcription initiation factor TFIID subunit 2 Transcription initiation factor TFIID subunit 3 Transcription initiation factor TFIID subunit 4 Transcription initiation factor TFIID subunit 4B Transcription initiation factor TFIID subunit 5 Transcription initiation factor TFIID subunit 6 Transcription initiation factor TFIID subunit 7-like Transcription initiation factor TFIID subunit 7 Transcription initiation factor TFIID subunit 9 Transcription initiation factor TFIID subunit 9B	O00268 O15514 P13984 P18074 P19387 P19388 P19447 P20226 P21675 P24928 P29083 P29084 P30876 P32780 P35269 P36954 P49848 P50613 P51946 P51948 P52434 P52435 P52655 P52657 P53803 P61218 P62487 P62875 Q00403 Q12962 Q13888 Q13889 Q15542 Q15543 Q15544 Q15545 Q16514 Q16594 Q5H9L4 Q5VWG9 Q6P1X5 Q6ZYL4 Q8IZX4 Q92750 Q92759 Q92804 Q9HBM6	BA2R BTF2 BTF2P44 C6orf175 CAK CAK1 CAP35 CCG1 CCGS CCNH CDK7 CDKN7 CIF150 ERCC2 ERCC3 GTF2A1 GTF2A2 GTF2B GTF2D1 GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 MAT1 MNAT1 MO15 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RBP56 RNF66 RPB7 STK1 TAF1 TAF10 TAF11 TAF12 TAF13 TAF15 TAF1L TAF2 TAF2A TAF2B TAF2C TAF2C1 TAF2C2 TAF2D TAF2E TAF2F TAF2G TAF2H TAF2I TAF2J TAF2K TAF2N TAF2Q TAF3 TAF4 TAF4A TAF4B TAF5 TAF6 TAF7 TAF7L TAF9 TAF9B TAF9L TAFII105 TAFII130 TAFII135 TAFII18 TAFII20 TAFII30 TAFII31 TAFII55 TAFII70 TBP TF2A1 TF2A2 TF2B TF2D TF2E1 TF2E2 TFIIB TFIID TTDA XPB XPBC XPD XPDC
Autodegradation of the E3 ubiquitin ligase COP1	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cellular tumor antigen p53 E3 ubiquitin-protein ligase COP1 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Serine-protein kinase ATM Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O43242 O75832 P04637 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q06323 Q13200 Q13315 Q14997 Q15008 Q16401 Q8NHY2 Q8TAA3 Q92530 Q99436 Q99460 Q9UL46 Q9UNM6	ATM C7orf76 COP1 DSS1 HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0077 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NU P53 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RFWD2 RING10 RING12 RNF200 RPS27A SEM1 SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TP53 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 Z
SIRT1 negatively regulates rRNA expression	Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Histone-lysine N-methyltransferase SUV39H1 NAD-dependent protein deacetylase sirtuin-1 Ribosomal RNA-processing protein 8 TATA box-binding protein-associated factor RNA polymerase I subunit A TATA box-binding protein-associated factor RNA polymerase I subunit B TATA box-binding protein-associated factor RNA polymerase I subunit C TATA box-binding protein-associated factor RNA polymerase I subunit D TATA-box-binding protein	O43159 O43463 O60814 P04908 P06899 P0C5Y9 P16104 P20226 P20671 P23527 P33778 P57053 P58876 P62805 P62807 P68431 P84243 Q15572 Q15573 Q16777 Q16778 Q53T94 Q6FI13 Q71DI3 Q71UI9 Q8N257 Q93077 Q93079 Q96A08 Q96EB6 Q99877 Q99878 Q99879 Q99880 Q9BTM1 Q9H5J8	GTF2D1 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 JOSD3 KIAA0409 KMT1A NML RRP8 SIR2L1 SIRT1 SUV39H SUV39H1 TAF1A TAF1B TAF1C TAF1D TBP TF2D TFIID TSH2B
Synthesis of bile acids and bile salts	Bile acid receptor Cholesterol 25-hydroxylase Cytochrome P450 7A1 Cytochrome P450 7B1 Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Oxysterol-binding protein 1 Oxysterol-binding protein-related protein 1 Oxysterol-binding protein-related protein 2 Oxysterol-binding protein-related protein 3 Oxysterol-binding protein-related protein 6 Oxysterol-binding protein-related protein 7 Oxysterol-binding protein-related protein 9 Retinoic acid receptor RXR-alpha	O75881 O95992 P19793 P22059 P22680 Q15596 Q15788 Q96RI1 Q96SU4 Q9BXW6 Q9BZF2 Q9BZF3 Q9H1P3 Q9H4L5	BAR BHLHE74 BHLHE75 CH25H CYP7 CYP7A1 CYP7B1 FXR HRR1 KIAA0704 KIAA0772 NCOA1 NCOA2 NR1H4 NR2B1 ORP1 ORP2 ORP3 ORP6 ORP7 ORP9 OSBP OSBP1 OSBP3 OSBP4 OSBP8 OSBPL1 OSBPL1A OSBPL1B OSBPL2 OSBPL3 OSBPL6 OSBPL7 OSBPL9 RIP14 RXRA SRC1 SRC2 TIF2
PTK6 Down-Regulation	Protein-tyrosine kinase 6 Tyrosine-protein kinase Srms Tyrosine-protein phosphatase non-receptor type 1	P18031 Q13882 Q9H3Y6	BRK C20orf148 PTK6 PTP1B PTPN1 SRMS
Metabolism of ingested MeSeO2H into MeSeH	Thioredoxin reductase 1, cytoplasmic	Q16881	GRIM12 KDRF TXNRD1
VEGF binds to VEGFR leading to receptor dimerization	Placenta growth factor Vascular endothelial growth factor A, long form Vascular endothelial growth factor B Vascular endothelial growth factor C Vascular endothelial growth factor D Vascular endothelial growth factor receptor 1 Vascular endothelial growth factor receptor 2 Vascular endothelial growth factor receptor 3	O43915 P15692 P17948 P35916 P35968 P49763 P49765 P49767	FIGF FLK1 FLT FLT1 FLT4 FRT KDR PGF PGFL PLGF VEGF VEGFA VEGFB VEGFC VEGFD VEGFR1 VEGFR2 VEGFR3 VRF

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