GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **1526 - 1550** of **2090** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	GlyTouCan ID
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	ATP-sensitive inward rectifier potassium channel 10 ATP-sensitive inward rectifier potassium channel 12 ATP-sensitive inward rectifier potassium channel 15 G protein-activated inward rectifier potassium channel 1 G protein-activated inward rectifier potassium channel 2 G protein-activated inward rectifier potassium channel 3 G protein-activated inward rectifier potassium channel 4 Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Inward rectifier potassium channel 16 Inward rectifier potassium channel 2 Inward rectifier potassium channel 4	O14610 O14775 O60262 O75899 P16520 P48050 P48051 P48544 P48549 P50150 P50151 P59768 P61952 P62873 P62879 P63211 P63215 P63218 P63252 P78508 Q14500 Q92806 Q99712 Q9HAV0 Q9NPI9 Q9P2W3 Q9UBI6 Q9UBS5 Q9UK08	GABBR1 GABBR2 GIRK1 GIRK2 GIRK3 GIRK4 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GPR51 GPRC3A GPRC3B IRK1 IRK2 IRK3 KATP2 KCNJ10 KCNJ12 KCNJ14 KCNJ15 KCNJ16 KCNJ2 KCNJ3 KCNJ4 KCNJ5 KCNJ6 KCNJ7 KCNJ9 KCNJN1
Ca2+ pathway	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 Calcineurin subunit B type 1 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calmodulin-1 Catenin beta-1 Frizzled-2 Frizzled-3 Frizzled-4 Frizzled-5 Frizzled-6 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(o) subunit alpha Guanine nucleotide-binding protein G(t) subunit alpha-2 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Helicase MOV-10 Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Lymphoid enhancer-binding factor 1 Mitogen-activated protein kinase kinase kinase 7 Nuclear factor of activated T-cells, cytoplasmic 1 Protein Wnt-11 Protein Wnt-5a Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Protein kinase C alpha type Protein phosphatase 3 catalytic subunit alpha Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta Serine/threonine-protein kinase NLK Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform Transcription factor 7-like 1 Transcription factor 7-like 2 Transcription factor 7 Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein cGMP-dependent protein kinase 1 cGMP-dependent protein kinase 2	O14610 O14775 O43318 O60262 O60353 O95644 O96014 P09471 P0DP23 P16298 P16499 P16520 P17252 P18545 P19087 P35222 P35913 P36402 P41221 P50150 P50151 P59768 P61952 P62873 P62879 P63098 P63211 P63215 P63218 Q00722 Q01970 Q08209 Q13237 Q13467 Q13976 Q14332 Q14571 Q14573 Q14643 Q8NDV7 Q9H9G7 Q9HAV0 Q9HCE1 Q9HCJ0 Q9HCK5 Q9HCS4 Q9NPG1 Q9NQ66 Q9NQB0 Q9P2W3 Q9UBE8 Q9UBI6 Q9UJU2 Q9UK08 Q9UKV8 Q9UL18 Q9ULV1 Q9UPQ9 Q9UQM7	AGO1 AGO2 AGO3 AGO4 C2orf31 CAGH26 CALM CALM1 CALNA CALNA2 CALNB CAM CAM1 CAMK2A CAMKA CNA CNA2 CNB CTNNB CTNNB1 EIF2C1 EIF2C2 EIF2C3 EIF2C4 FZD2 FZD3 FZD4 FZD5 FZD6 GNAO1 GNAT2 GNATC GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 INSP3R1 ITPR1 ITPR2 ITPR3 KIAA0581 KIAA0968 KIAA1093 KIAA1460 KIAA1567 KIAA1582 KIAA1631 LAK1 LEF1 MAP3K7 MOV10 NFAT2 NFATC NFATC1 NLK PDE6A PDE6B PDE6G PDEA PDEB PDEG PKCA PLCB1 PLCB2 PLCB3 PPP3CA PPP3CB PPP3R1 PRKACA PRKCA PRKG1 PRKG1B PRKG2 PRKGR1A PRKGR1B PRKGR2 TAK1 TCF1 TCF3 TCF4 TCF7 TCF7L1 TCF7L2 TNRC6 TNRC6A TNRC6B TNRC6C WNT11 WNT5A
Adrenaline,noradrenaline inhibits insulin secretion	Adenylate cyclase type 5 Adenylate cyclase type 6 Alpha-2A adrenergic receptor Alpha-2C adrenergic receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Voltage-dependent L-type calcium channel subunit alpha-1C Voltage-dependent L-type calcium channel subunit alpha-1D Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent L-type calcium channel subunit beta-3 Voltage-dependent calcium channel subunit alpha-2/delta-2	O14610 O14775 O43306 O60262 O95622 P04899 P08913 P16520 P18825 P50150 P50151 P54284 P59768 P61952 P62873 P62879 P63096 P63211 P63215 P63218 Q01668 Q08289 Q13936 Q9HAV0 Q9NY47 Q9P2W3 Q9UBI6 Q9UK08	ADCY5 ADCY6 ADRA2A ADRA2C ADRA2L2 ADRA2R ADRA2RL2 ADRAR CACH2 CACH3 CACN2 CACN4 CACNA1C CACNA1D CACNA2D2 CACNB2 CACNB3 CACNL1A1 CACNL1A2 CACNLB2 CACNLB3 CCHL1A1 CCHL1A2 GNAI1 GNAI2 GNAI2B GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 KIAA0422 KIAA0558 MYSB
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	A-kinase anchor protein 5 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 8 Glucagon-like peptide 1 receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Potassium voltage-gated channel subfamily B member 1 Potassium voltage-gated channel subfamily C member 2 Potassium voltage-gated channel subfamily G member 2 Potassium voltage-gated channel subfamily S member 3 Pro-glucagon Rap guanine nucleotide exchange factor 3 Rap guanine nucleotide exchange factor 4 Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	O14610 O14775 O43306 O60262 O95398 O95622 P01275 P10644 P13861 P16520 P17612 P22612 P22694 P24588 P31321 P31323 P40145 P43220 P46940 P50150 P50151 P59768 P61952 P62834 P62873 P62879 P63092 P63211 P63215 P63218 Q14571 Q14573 Q14643 Q14721 Q5JWF2 Q8WZA2 Q96PR1 Q9BQ31 Q9HAV0 Q9P2W3 Q9UBI6 Q9UJ96 Q9UK08	ADCY5 ADCY6 ADCY8 AKAP5 AKAP79 CGEF1 CGEF2 EPAC EPAC1 EPAC2 GCG GLP1R GNAS GNAS1 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GSP INSP3R1 IQGAP1 ITPR1 ITPR2 ITPR3 KCNB1 KCNC2 KCNF2 KCNG2 KCNS3 KIAA0051 KIAA0422 KREV1 PKACA PKR1 PKR2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B RAP1A RAPGEF3 RAPGEF4 TSE1
Vasopressin regulates renal water homeostasis via Aquaporins	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Aquaporin-1 Aquaporin-2 Aquaporin-3 Aquaporin-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Rab11 family-interacting protein 2 Ras-related protein Rab-11A Unconventional myosin-Vb Vasopressin V2 receptor Vasopressin-neurophysin 2-copeptin cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	O14610 O14775 O43306 O60262 O60266 O60503 O95622 P01185 P10644 P13861 P16520 P17612 P22612 P22694 P29972 P30518 P31321 P31323 P40145 P41181 P50150 P50151 P51828 P55087 P59768 P61952 P62491 P62873 P62879 P63092 P63211 P63215 P63218 Q08462 Q08828 Q5JWF2 Q7L804 Q8NFM4 Q92482 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08 Q9ULV0	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADHR AQP1 AQP2 AQP3 AQP4 ARVP AVP AVPR2 CHIP28 DIR DIR3 GNAS GNAS1 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GSP KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA0941 KIAA1060 KIAA1119 MYO5B PKACA PKR1 PKR2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B RAB11 RAB11A RAB11FIP2 TSE1 V2R VP
G beta:gamma signalling through PI3Kgamma	3-phosphoinositide-dependent protein kinase 1 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Phosphoinositide 3-kinase regulatory subunit 5 Phosphoinositide 3-kinase regulatory subunit 6 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Transforming protein RhoA	O14610 O14775 O15530 O60262 P16520 P31749 P31751 P48736 P50150 P50151 P59768 P61586 P61952 P62873 P62879 P63211 P63215 P63218 Q5UE93 Q8WYR1 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08 Q9Y243	AKT1 AKT2 AKT3 ARH12 ARHA C17orf38 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 PDK1 PDPK1 PIK3CG PIK3R5 PIK3R6 PKB PKBG RAC RHO12 RHOA
HDMs demethylate histones	AT-rich interactive domain-containing protein 5B Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 Histone H3.1 Histone H3.2 Histone H4 Histone demethylase UTY Histone lysine demethylase PHF8 Lysine-specific demethylase 2A Lysine-specific demethylase 2B Lysine-specific demethylase 3A Lysine-specific demethylase 3B Lysine-specific demethylase 4A Lysine-specific demethylase 4B Lysine-specific demethylase 4C Lysine-specific demethylase 4D Lysine-specific demethylase 5A Lysine-specific demethylase 5B Lysine-specific demethylase 5C Lysine-specific demethylase 5D Lysine-specific demethylase 6A Lysine-specific demethylase 6B Lysine-specific demethylase 7A Lysine-specific demethylase PHF2 Lysine-specific histone demethylase 1A Lysine-specific histone demethylase 2 Ribosomal oxygenase 2	O14607 O15054 O15550 O60341 O75151 O75164 O94953 P29375 P41229 P62805 P68431 Q14865 Q6B0I6 Q6NYC1 Q6ZMT4 Q71DI3 Q7LBC6 Q8IUF8 Q8NB78 Q8NHM5 Q9BY66 Q9H3R0 Q9UGL1 Q9UPP1 Q9Y2K7 Q9Y4C1	AOF1 AOF2 ARID5B C5orf7 C6orf193 CENP-35 CXXC2 CXXC8 DESRT DXS1272E FBL10 FBL11 FBL7 FBXL10 FBXL11 GASC1 H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST4H4 HY HYA JARID1A JARID1B JARID1C JARID1D JHDM1A JHDM1B JHDM1D JHDM2A JHDM2B JHDM3A JHDM3B JHDM3C JHDM3D JMJD1 JMJD1A JMJD1B JMJD2 JMJD2A JMJD2B JMJD2C JMJD2D JMJD3 JMJD6 KDM1 KDM1A KDM1B KDM2A KDM2B KDM3A KDM3B KDM4A KDM4B KDM4C KDM4D KDM5A KDM5B KDM5C KDM5D KDM6A KDM6B KDM6C KDM7 KDM7A KIAA0234 KIAA0346 KIAA0585 KIAA0601 KIAA0662 KIAA0677 KIAA0742 KIAA0780 KIAA0876 KIAA1004 KIAA1082 KIAA1111 KIAA1718 LSD1 LSD2 MDIG MINA MINA53 MRF2 NDY1 NO52 PCCX2 PHF2 PHF8 PLU1 PSR PTDSR RBBP2 RBBP2H1 RBP2 RIOX2 SMCX SMCY TSGA UTX UTY XE169 ZNF422
XBP1(S) activates chaperone genes	ADP-ribosylation factor GTPase-activating protein 1 ATP-dependent DNA helicase DDX11 Alpha-adducin CXXC-type zinc finger protein 1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 Cullin-7 Cytosolic phospholipase A2 beta DnaJ homolog subfamily B member 11 DnaJ homolog subfamily B member 9 DnaJ homolog subfamily C member 3 Dynactin subunit 1 E3 ubiquitin-protein ligase synoviolin ER degradation-enhancing alpha-mannosidase-like protein 1 ER lumen protein-retaining receptor 3 Exostosin-like 1 Exostosin-like 2 Exostosin-like 3 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 Glycogen synthase kinase-3 alpha Golgi SNAP receptor complex member 2 Guanine nucleotide-exchange factor SEC12 Hepatoma-derived growth factor Hypoxia up-regulated protein 1 Kelch domain-containing protein 3 Myeloid-derived growth factor Peptidyl-prolyl cis-trans isomerase FKBP14 Prelamin-A/C Protein YIF1A Protein disulfide-isomerase A5 Protein disulfide-isomerase A6 Protein transport protein Sec31A Putative deoxyribonuclease TATDN2 SHC-transforming protein 1 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Signal recognition particle receptor subunit alpha Signal recognition particle receptor subunit beta Stress-associated endoplasmic reticulum protein 1 Sulfotransferase 1A3 Talin-1 Testis-specific Y-encoded-like protein 2 Translocon-associated protein subunit alpha Tripeptidyl-peptidase 1 V-type proton ATPase subunit d 1 Very long-chain specific acyl-CoA dehydrogenase, mitochondrial WD repeat domain phosphoinositide-interacting protein 1 Wolframin Zinc finger and BTB domain-containing protein 17	O14595 O14653 O14773 O43731 O43909 O76024 O94979 O95070 P02545 P08240 P0C869 P0DMM9 P29353 P35611 P43307 P49748 P49840 P51858 P61421 Q06210 Q13105 Q13217 Q14203 Q14554 Q14999 Q15084 Q15173 Q5MNZ9 Q86TM6 Q8N6T3 Q92611 Q92935 Q93075 Q969H8 Q96FC9 Q9BQ90 Q9H2G4 Q9HCU5 Q9NWM8 Q9P0U4 Q9UBQ6 Q9UBS3 Q9UBS4 Q9Y490 Q9Y4L1 Q9Y5M8 Q9Y6X1	54TM ACADVL ADD1 ADDA ARF1GAP ARFGAP1 ATP6D ATP6V0D1 C19orf10 CDA1 CFP1 CGBP CHL1 CHLR1 CLN2 CTDSP2 CUL7 CXXC1 DCTN1 DDX11 DENTT DNAJB11 DNAJB9 DNAJC3 EDEM EDEM1 EDJ ERD23 ERJ3 ERP5 EXTL EXTL1 EXTL1L EXTL2 EXTL3 EXTR1 EXTR2 FKBP14 FKBP22 GFAT GFPT GFPT1 GOSR2 GRP170 GS27 GSK3A HDGF HDJ9 HMG1L2 HRD1 HSPH4 HYIF1P HYOU1 KDELR3 KIAA0076 KIAA0212 KIAA0218 KIAA0519 KIAA0905 KIAA1027 KIAA1810 KLHDC3 KRG2 LMN1 LMNA MDG1 MIZ1 MYDGF NIF2 ORP150 OS4 P5 P58IPK PCCX1 PDIA5 PDIA6 PDIR PEAS PHF18 PLA2G4B PPP2R5B PREB PRKRI RAMP4 SCP2 SEC12 SEC31A SEC31L1 SERP1 SHC SHC1 SHCA SRPR SRPRA SRPRB SSR1 STM SULT1A3 SYVN1 TATDN2 TLN TLN1 TPP1 TRAPA TSPX TSPYL2 TXNDC7 VLCAD VPATPD WFS1 WIPI1 WIPI49 YIF1 YIF1A ZBTB17 ZNF151 ZNF60
L1CAM interactions	Acyl-protein thioesterase 2 CD166 antigen Contactin-1 Contactin-2 Ephrin type-B receptor 2 Laminin subunit alpha-1 Laminin subunit beta-1 Laminin subunit gamma-1 Neural cell adhesion molecule L1 Neurocan core protein Neuromodulin Ran-binding protein 9 Signal transducer CD24	O14594 O95372 P07942 P11047 P17677 P25063 P25391 P29323 P32004 Q02246 Q12860 Q13740 Q96S59	ALCAM APT2 AXT CAML1 CD24 CD24A CNTN1 CNTN2 CSPG3 DRT EPHB2 EPHT3 EPTH3 ERK GAP43 HEK5 L1CAM LAMA LAMA1 LAMB1 LAMB2 LAMC1 LYPLA2 MEMD MIC5 NCAN NEUR RANBP9 RANBPM TAG1 TAX1 TYRO5
Defective CHST14 causes EDS, musculocontractural type	Biglycan Brevican core protein Carbohydrate sulfotransferase 14 Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Neurocan core protein Versican core protein	O14594 O95196 P07585 P13611 P21810 Q6UVK1 Q8NCH0 Q96GW7	BCAN BEHAB BGN CALEB CHST14 CSPG2 CSPG3 CSPG4 CSPG5 CSPG7 D4ST1 DCN MCSP NCAN NEUR NGC SLRR1A SLRR1B VCAN
Dermatan sulfate biosynthesis	Biglycan Brevican core protein Carbohydrate sulfotransferase 14 Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Dermatan-sulfate epimerase-like protein Dermatan-sulfate epimerase Neurocan core protein Uronyl 2-sulfotransferase Versican core protein	O14594 O95196 P07585 P13611 P21810 Q6UVK1 Q8IZU8 Q8NCH0 Q96GW7 Q9UL01 Q9Y2C2	BCAN BEHAB BGN C18orf4 CALEB CHST14 CSPG2 CSPG3 CSPG4 CSPG5 CSPG7 D4ST1 DCN DS2ST DSE DSEL MCSP NCAG1 NCAN NEUR NGC SART2 SLRR1A SLRR1B UST VCAN
Defective CHSY1 causes TPBS	Biglycan Brevican core protein Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Chondroitin sulfate synthase 1 Decorin Neurocan core protein Versican core protein	O14594 O95196 P07585 P13611 P21810 Q6UVK1 Q86X52 Q96GW7	BCAN BEHAB BGN CALEB CHSY CHSY1 CSPG2 CSPG3 CSPG4 CSPG5 CSPG7 CSS1 DCN KIAA0990 MCSP NCAN NEUR NGC SLRR1A SLRR1B VCAN
Defective CHST3 causes SEDCJD	Biglycan Brevican core protein Carbohydrate sulfotransferase 3 Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Neurocan core protein Versican core protein	O14594 O95196 P07585 P13611 P21810 Q6UVK1 Q7LGC8 Q96GW7	BCAN BEHAB BGN CALEB CHST3 CSPG2 CSPG3 CSPG4 CSPG5 CSPG7 DCN MCSP NCAN NEUR NGC SLRR1A SLRR1B VCAN
Chondroitin sulfate biosynthesis	Biglycan Brevican core protein Carbohydrate sulfotransferase 11 Carbohydrate sulfotransferase 12 Carbohydrate sulfotransferase 13 Carbohydrate sulfotransferase 15 Carbohydrate sulfotransferase 3 Carbohydrate sulfotransferase 7 Chondroitin sulfate N-acetylgalactosaminyltransferase 1 Chondroitin sulfate N-acetylgalactosaminyltransferase 2 Chondroitin sulfate glucuronyltransferase Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Chondroitin sulfate synthase 1 Chondroitin sulfate synthase 2 Chondroitin sulfate synthase 3 Decorin Neurocan core protein Versican core protein	O14594 O95196 P07585 P13611 P21810 Q6UVK1 Q70JA7 Q7LFX5 Q7LGC8 Q86X52 Q8IZ52 Q8N6G5 Q8NET6 Q8TDX6 Q96GW7 Q9NPF2 Q9NRB3 Q9NS84 Q9P2E5	BCAN BEHAB BGN BRAG CALEB CHGN CHGN2 CHPF CHPF2 CHST11 CHST12 CHST13 CHST15 CHST3 CHST7 CHSY CHSY1 CHSY2 CHSY3 CSGALNACT1 CSGALNACT2 CSGLCAT CSPG2 CSPG3 CSPG4 CSPG5 CSPG7 CSS1 CSS2 CSS3 DCN GALNAC4S6ST GALNACT1 GALNACT2 KIAA0598 KIAA0990 KIAA1402 MCSP NCAN NEUR NGC SLRR1A SLRR1B VCAN
CS/DS degradation	Alpha-L-iduronidase Arylsulfatase B Beta-hexosaminidase subunit alpha Beta-hexosaminidase subunit beta Biglycan Brevican core protein Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Hyaluronidase-1 Hyaluronidase-3 Iduronate 2-sulfatase Neurocan core protein Versican core protein	O14594 O43820 O95196 P06865 P07585 P07686 P13611 P15848 P21810 P22304 P35475 Q12794 Q6UVK1 Q96GW7	ARSB BCAN BEHAB BGN CALEB CSPG2 CSPG3 CSPG4 CSPG5 CSPG7 DCN HEXA HEXB HYAL1 HYAL3 IDS IDUA LUCA1 LUCA3 MCSP NCAN NEUR NGC SIDS SLRR1A SLRR1B VCAN	G27025MB
RHO GTPases activate CIT	Citron Rho-interacting kinase Cyclin-dependent kinase inhibitor 1B Disks large homolog 4 Kinesin-like protein KIF14 Myosin light polypeptide 6 Myosin regulatory light chain 12B Myosin regulatory light polypeptide 9 Myosin-10 Myosin-11 Myosin-14 Myosin-9 Protein phosphatase 1 regulatory subunit 12A Protein phosphatase 1 regulatory subunit 12B Protein regulator of cytokinesis 1 Ras-related C3 botulinum toxin substrate 1 Rho-related GTP-binding protein RhoB Rho-related GTP-binding protein RhoC Serine/threonine-protein phosphatase PP1-beta catalytic subunit Transforming protein RhoA	O14578 O14950 O14974 O43663 O60237 P08134 P24844 P35579 P35580 P35749 P46527 P60660 P61586 P62140 P62745 P63000 P78352 Q15058 Q7Z406	ARH12 ARH6 ARH9 ARHA ARHB ARHC CDKN1B CIT CRIK DLG4 KIAA0042 KIAA0866 KIAA0949 KIAA2034 KIF14 KIP1 MBS MLC2 MRLC1 MRLC2 MYH10 MYH11 MYH14 MYH9 MYL12B MYL6 MYL9 MYLC2B MYPT1 MYPT2 MYRL2 PPP1CB PPP1R12A PPP1R12B PRC1 PSD95 RAC1 RHO12 RHOA RHOB RHOC STK21 TC25 p27
Aggrephagy	ADP-ribosylation factor-like protein 13B Centrin-1 Cystic fibrosis transmembrane conductance regulator Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic E3 ubiquitin-protein ligase parkin Heat shock factor protein 1 Heat shock protein HSP 90-alpha Histone deacetylase 6 Intraflagellar transport protein 88 homolog Parkinson disease protein 7 Pericentrin Polyubiquitin-B Polyubiquitin-C Transitional endoplasmic reticulum ATPase Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14576 O43237 O60260 O95613 P07900 P0CG47 P0CG48 P13569 P55072 P61088 P62979 P62987 P63167 Q00613 Q12798 Q13099 Q13404 Q13409 Q14204 Q3SXY8 Q96FJ2 Q99497 Q9UBN7 Q9Y6G9	ABCC7 ARL13B ARL2L1 BLU CEN1 CETN CETN1 CFTR CROC1 DHC1 DLC1 DLC2 DNCH1 DNCI1 DNCI2 DNCIC1 DNCIC2 DNCL DNCL1 DNCLC1 DNCLI1 DNCLI2 DNECL DYHC DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 HDAC6 HDLC1 HEL-220 HEL-S-70 HSF1 HSP90A HSP90AA1 HSPC1 HSPCA HSTF1 IFT88 KIAA0325 KIAA0402 KIAA0901 LIC2 PARK2 PARK7 PCNT PCNT2 PRKN RPS27A TG737 TTC10 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBE2N UBE2V UBE2V1 UEV1 VCP
PTK6 Activates STAT3	Protein-tyrosine kinase 6 Signal transducer and activator of transcription 3 Signal-transducing adaptor protein 2 Suppressor of cytokine signaling 3	O14543 P40763 Q13882 Q9UGK3	APRF BKS BRK CIS3 PTK6 SOCS3 SSI3 STAP2 STAT3
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	Cathepsin K Cathepsin L2 Core-binding factor subunit beta Procathepsin L Runt-related transcription factor 1 Serpin B13 Suppressor of cytokine signaling 3 Suppressor of cytokine signaling 4	O14543 O60911 P07711 P43235 Q01196 Q13951 Q8WXH5 Q9UIV8	AML1 CATL2 CBFA2 CBFB CIS3 CTSK CTSL CTSL1 CTSL2 CTSO CTSO2 CTSU CTSV PI13 RUNX1 SERPINB13 SOCS3 SOCS4 SOCS7 SSI3
Signaling by Leptin	Insulin receptor substrate 1 Insulin receptor substrate 2 Leptin Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK2 Tyrosine-protein phosphatase non-receptor type 11	O14543 O60674 P35568 P40763 P41159 P42229 P51692 Q06124 Q9Y4H2	APRF CIS3 IRS1 IRS2 JAK2 LEP OB OBS PTP2C PTPN11 SHPTP2 SOCS3 SSI3 STAT3 STAT5 STAT5A STAT5B
Interleukin-6 signaling	E3 ubiquitin-protein ligase CBL Interleukin-6 receptor subunit alpha Interleukin-6 receptor subunit beta Interleukin-6 Non-receptor tyrosine-protein kinase TYK2 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein phosphatase non-receptor type 11	O14543 O60674 P05231 P08887 P22681 P23458 P29597 P40189 P40763 P42224 Q06124	APRF CBL CBL2 CIS3 IFNB2 IL6 IL6R IL6ST JAK1 JAK1A JAK1B JAK2 PTP2C PTPN11 RNF55 SHPTP2 SOCS3 SSI3 STAT1 STAT3 TYK2
Regulation of IFNA/IFNB signaling	Interferon alpha-1/13 Interferon alpha-10 Interferon alpha-14 Interferon alpha-16 Interferon alpha-17 Interferon alpha-21 Interferon alpha-2 Interferon alpha-4 Interferon alpha-5 Interferon alpha-6 Interferon alpha-7 Interferon alpha-8 Interferon alpha/beta receptor 1 Interferon beta Non-receptor tyrosine-protein kinase TYK2 Signal transducer and activator of transcription 2 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK1 Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 1 Tyrosine-protein phosphatase non-receptor type 6 Ubl carboxyl-terminal hydrolase 18	O14543 O15524 P01562 P01563 P01566 P01567 P01568 P01569 P01570 P01571 P01574 P05013 P05014 P05015 P17181 P18031 P23458 P29350 P29597 P32881 P52630 Q06124 Q9UMW8	CIS3 HCP IFB IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA2A IFNA2B IFNA2C IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNAR IFNAR1 IFNB IFNB1 ISG43 JAK1 JAK1A JAK1B PTP1B PTP1C PTP2C PTPN1 PTPN11 PTPN6 SHPTP2 SOCS1 SOCS3 SSI1 SSI3 STAT2 TIP3 TYK2 USP18
Inactivation of CSF3 (G-CSF) signaling	Cullin-5 Elongin-B Elongin-C Granulocyte colony-stimulating factor receptor Granulocyte colony-stimulating factor Non-receptor tyrosine-protein kinase TYK2 Polyubiquitin-B Polyubiquitin-C RING-box protein 2 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase HCK Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14543 O15524 O60674 P07948 P08631 P09919 P0CG47 P0CG48 P23458 P29597 P40763 P42224 P42229 P43405 P51668 P51692 P61077 P62837 P62979 P62987 Q15369 Q15370 Q93034 Q99062 Q9UBF6	APRF C17orf33 CIS3 CSF3 CSF3R CUL5 ELOB ELOC GCSF GCSFR HCK JAK1 JAK1A JAK1B JAK2 JTK8 LYN PUBC1 RBX2 RNF7 ROC2 RPS27A SAG SFT SOCS1 SOCS3 SSI1 SSI3 STAT1 STAT3 STAT5 STAT5A STAT5B SYK TCEB1 TCEB2 TIP3 TYK2 UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBC5C UBCEP1 UBCEP2 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBE2D1 UBE2D2 UBE2D3 VACM1
Signaling by CSF3 (G-CSF)	GRB2-associated-binding protein 2 GTPase KRas Granulocyte colony-stimulating factor receptor Granulocyte colony-stimulating factor Growth factor receptor-bound protein 2 Non-receptor tyrosine-protein kinase TYK2 SHC-transforming protein 1 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase HCK Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Tyrosine-protein phosphatase non-receptor type 11	O14543 O15524 O60674 P01116 P07948 P08631 P09919 P23458 P29353 P29597 P40763 P42224 P42229 P43405 P51692 P62993 Q06124 Q99062 Q9UQC2	APRF ASH C17orf33 CIS3 CSF3 CSF3R GAB2 GCSF GCSFR GRB2 HCK JAK1 JAK1A JAK1B JAK2 JTK8 KIAA0571 KRAS KRAS2 LYN PTP2C PTPN11 RASK2 SHC SHC1 SHCA SHPTP2 SOCS1 SOCS3 SSI1 SSI3 STAT1 STAT3 STAT5 STAT5A STAT5B SYK TIP3 TYK2
Regulation of IFNG signaling	E3 SUMO-protein ligase PIAS1 Interferon gamma receptor 1 Interferon gamma receptor 2 Interferon gamma Small ubiquitin-related modifier 1 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 1 Tyrosine-protein phosphatase non-receptor type 6	O14543 O15524 O60674 O75925 P01579 P15260 P18031 P23458 P29350 P38484 P63165 Q06124	CIS3 DDXBP1 HCP IFNG IFNGR1 IFNGR2 IFNGT1 JAK1 JAK1A JAK1B JAK2 PIAS1 PTP1B PTP1C PTP2C PTPN1 PTPN11 PTPN6 SHPTP2 SMT3C SMT3H3 SOCS1 SOCS3 SSI1 SSI3 SUMO1 TIP3 UBL1

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