GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1201 - 1225** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism
Regulation of CDH11 gene transcription	Class E basic helix-loop-helix protein 22 Forkhead box protein F1 Hairy/enhancer-of-split related with YRPW motif-like protein Homeobox protein Hox-C8 Interleukin enhancer-binding factor 3 PR domain zinc finger protein 8 Transcription factor Sp1 Zinc finger E-box-binding homeobox 2 Zinc finger protein SNAI1	O60315 O95863 P08047 P31273 Q12906 Q12946 Q8NFJ8 Q9NQ87 Q9NQV8	BHLHB33 BHLHB5 BHLHE22 DRBF FKHL5 FOXF1 FREAC1 HEYL HOX3A HOXC8 HRT3 ILF3 KIAA0569 MPHOSPH4 NF90 PFM5 PRDM8 SIP1 SNAH SNAI1 SP1 TNRC20 TSFP1 ZEB2 ZFHX1B ZFX1B	Homo sapiens (human)
Somitogenesis	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe Catenin beta-1 Delta-like protein 1 Delta-like protein 3 Ephrin type-A receptor 4 Lymphoid enhancer-binding factor 1 Mesoderm posterior protein 2 Mesogenin-1 Neurogenic locus notch homolog protein 1 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein ripply2 Recombining binding protein suppressor of hairless T-box transcription factor TBX6 Transcription factor HES-7	A6NI15 O00231 O00232 O00233 O00487 O00548 O14818 O43242 O75832 O95947 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35222 P35998 P40306 P43686 P46531 P48556 P49720 P49721 P51665 P54764 P55036 P60896 P60900 P61289 P62191 P62195 P62333 Q06323 Q06330 Q0VG99 Q13200 Q15008 Q16401 Q5TAB7 Q8NES3 Q92530 Q99436 Q99460 Q9BYE0 Q9NYJ7 Q9UJU2 Q9UL46 Q9UNM6	BHLHB37 BHLHC6 C6orf159 C7orf76 CTNNB CTNNB1 DLL1 DLL3 DSS1 EPHA4 HC2 HC3 HC8 HC9 HEK8 HES7 HSPC IFI5111 IGKJRB IGKJRB1 KIAA0072 KIAA0107 LEF1 LFNG LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MESP2 MIP224 MOV34L MSGN1 MSS1 NOTCH1 NU PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSMF1 RBPJ RBPJK RBPSUH RING10 RING12 RIPPLY2 SCDO2 SEK SEM1 SHFDG1 SHFM1 SUG1 SUG2 TAN1 TBP1 TBP7 TBX6 TRAP2 TYRO1 X Y Y2 Z	Homo sapiens (human)
NOTCH2 intracellular domain regulates transcription	Granzyme B Histone acetyltransferase p300 Low affinity immunoglobulin epsilon Fc receptor Mastermind-like domain-containing protein 1 Mastermind-like protein 1 Mastermind-like protein 2 Mastermind-like protein 3 Neurogenic locus notch homolog protein 2 Recombining binding protein suppressor of hairless Transcription factor HES-1 Transcription factor HES-5	P06734 P10144 Q04721 Q06330 Q09472 Q13495 Q14469 Q5TA89 Q8IZL2 Q92585 Q96JK9	BHLHB38 BHLHB39 CD23A CG1 CGL1 CLEC4J CSPB CTLA1 CXorf6 EP300 FCE2 FCER2 GRB GZMB HES1 HES5 HL HRY IGEBF IGKJRB IGKJRB1 KIAA0200 KIAA1816 KIAA1819 MAML1 MAML2 MAML3 MAMLD1 NOTCH2 P300 RBPJ RBPJK RBPSUH	Homo sapiens (human)
PKA-mediated phosphorylation of key metabolic factors	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 Carbohydrate-responsive element-binding protein cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	P16118 P17612 P22612 P22694 Q9NP71	BHLHD14 F6PK MIO MLXIPL PFKFB1 PFRX PKACA PRKACA PRKACB PRKACG WBSCR14	Homo sapiens (human)
PP2A-mediated dephosphorylation of key metabolic factors	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 Carbohydrate-responsive element-binding protein Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	P16118 P30153 P30154 P62714 P67775 Q14738 Q9NP71	BHLHD14 F6PK MIO MLXIPL PFKFB1 PFRX PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D WBSCR14	Homo sapiens (human)
SUMOylation of transcription factors	Cellular tumor antigen p53 E3 SUMO-protein ligase PIAS1 E3 SUMO-protein ligase PIAS3 E3 SUMO-protein ligase PIAS4 E3 ubiquitin-protein ligase Mdm2 Forkhead box protein L2 Hypermethylated in cancer 1 protein Metastasis-associated protein MTA1 Microphthalmia-associated transcription factor SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3 TP53-binding protein 1 Transcription factor AP-2 gamma Transcription factor AP-2-beta Transcription factor Sp3 Tumor suppressor ARF	O75030 O75925 P04637 P55854 P58012 P61956 P63165 P63279 Q00987 Q02447 Q12888 Q13330 Q14526 Q8N2W9 Q8N726 Q92481 Q92754 Q9Y6X2	BHLHE32 CDKN2 CDKN2A DDXBP1 FOXL2 HIC1 MDM2 MITF MLM MTA1 P53 PIAS1 PIAS3 PIAS4 PIASG SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 SP3 SUMO1 SUMO2 SUMO3 TFAP2B TFAP2C TP53 TP53BP1 UBC9 UBCE9 UBE2I UBL1 ZBTB29	Homo sapiens (human)
Regulation of NFE2L2 gene expression	CREB-binding protein Histone acetyltransferase p300 Myc proto-oncogene protein Neurogenic locus notch homolog protein 1 Nuclear factor NF-kappa-B p105 subunit Nuclear factor erythroid 2-related factor 2 Transcription factor MafK Transcription factor p65	O60675 P01106 P19838 P46531 Q04206 Q09472 Q16236 Q92793	BHLHE39 CBP CREBBP EP300 MAFK MYC NFE2L2 NFKB1 NFKB3 NOTCH1 NRF2 P300 RELA TAN1	Homo sapiens (human)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	Collagen alpha-2(I) chain Cyclin-C Cyclin-K Cyclin-T1 Cyclin-T2 Cyclin-dependent kinase 4 inhibitor B Cyclin-dependent kinase 8 Cyclin-dependent kinase 9 E3 ubiquitin-protein ligase Arkadia Furin Histone acetyltransferase p300 Histone deacetylase 1 Homeobox protein TGIF1 Homeobox protein TGIF2 Menin Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Mothers against decapentaplegic homolog 7 Myc proto-oncogene protein Plasminogen activator inhibitor 1 Polyubiquitin-B Polyubiquitin-C Retinoblastoma-like protein 1 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F4 Transcription factor E2F5 Transcription factor JunB Transcription factor Sp1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein WW domain-containing transcription regulator protein 1 Y-box-binding protein 1	O00255 O15105 O60563 O60583 O75909 P01106 P05121 P08047 P08123 P09958 P0CG47 P0CG48 P17275 P24863 P27361 P28482 P28749 P42772 P49336 P50750 P62979 P62987 P67809 P84022 Q09472 Q13485 Q13547 Q14186 Q14188 Q15329 Q15583 Q15796 Q16254 Q6ZNA4 Q9GZN2 Q9GZV5	BHLHE39 CCNC CCNK CCNT1 CCNT2 CDC2L4 CDK8 CDK9 CDKN2B COL1A2 CPR4 DP1 DP2 DPC4 E2F4 E2F5 EP300 ERK1 ERK2 FUR FURIN HDAC1 JUNB MADH2 MADH3 MADH4 MADH7 MADH8 MADR2 MAPK1 MAPK3 MEN1 MTS2 MYC NSEP1 P300 PACE PAI1 PCSK3 PLANH1 PRKM1 PRKM2 PRKM3 RBL1 RNF111 RPD3L1 RPS27A SCG2 SERPINE1 SMAD2 SMAD3 SMAD4 SMAD7 SP1 TAK TAZ TFDP1 TFDP2 TGIF TGIF1 TGIF2 TSFP1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WWTR1 YB1 YBX1	Homo sapiens (human)
PTK6 Expression	Endothelial PAS domain-containing protein 1 Glucocorticoid receptor Hypoxia-inducible factor 1-alpha Proline-, glutamic acid- and leucine-rich protein 1 Protein-tyrosine kinase 6	P04150 Q13882 Q16665 Q8IZL8 Q99814	BHLHE73 BHLHE78 BRK EPAS1 GRL HIF1A HIF2A HMX3 MNAR MOP1 MOP2 NR3C1 PASD2 PASD8 PELP1 PTK6	Homo sapiens (human)
Cellular response to hypoxia	Endothelial PAS domain-containing protein 1 Hypoxia-inducible factor 1-alpha inhibitor Hypoxia-inducible factor 1-alpha	Q16665 Q99814 Q9NWT6	BHLHE73 BHLHE78 EPAS1 FIH1 HIF1A HIF1AN HIF2A MOP1 MOP2 PASD2 PASD8	Homo sapiens (human)
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2	Bone morphogenetic protein 7 Chromodomain-helicase-DNA-binding protein 3 Chromodomain-helicase-DNA-binding protein 4 Cytochrome c oxidase subunit 7A1, mitochondrial Heterogeneous nuclear ribonucleoprotein U Histone deacetylase 1 Histone deacetylase 2 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Histone-lysine N-methyltransferase PRDM16 Lipid transferase CIDEA Metastasis-associated protein MTA1 Metastasis-associated protein MTA2 Metastasis-associated protein MTA3 Methyl-CpG-binding domain protein 3 Mitochondrial brown fat uncoupling protein 1 Mothers against decapentaplegic homolog 1 Mothers against decapentaplegic homolog 4 Nuclear receptor coactivator 1 Peroxisome proliferator-activated receptor alpha Peroxisome proliferator-activated receptor gamma coactivator 1-alpha Peroxisome proliferator-activated receptor gamma coactivator 1-beta Peroxisome proliferator-activated receptor gamma Retinoic acid receptor RXR-alpha Transcription factor COE2 Transcriptional repressor p66-alpha Transcriptional repressor p66-beta Type II iodothyronine deiodinase Very long chain fatty acid elongase 3 Zinc finger protein 423	O60543 O94776 O95983 P18075 P19793 P24310 P25874 P37231 Q00839 Q07869 Q09028 Q12873 Q13330 Q13485 Q13547 Q14839 Q15788 Q15797 Q16576 Q2M1K9 Q86YN6 Q86YP4 Q8WXI9 Q92769 Q92813 Q9BTC8 Q9HAK2 Q9HAZ2 Q9HB03 Q9UBK2	BHLHE74 BMP7 BSP1 C1orf199 CHD3 CHD4 CIDEA CIG30 COE2 COX7A1 COX7AH DIO2 DPC4 EBF2 ELOVL3 GATAD2A GATAD2B HDAC1 HDAC2 HNRNPU HNRPU ITDI2 KIAA0760 KIAA1150 KIAA1266 KIAA1675 LEM6 MADH1 MADH4 MADR1 MBD3 MEL1 MTA1 MTA1L1 MTA2 MTA3 NCOA1 NPHP14 NR1C1 NR1C3 NR2B1 OAZ OP1 PERC PFM13 PGC1 PGC1A PGC1B PID PPAR PPARA PPARG PPARGC1 PPARGC1A PPARGC1B PRDM16 RBAP46 RBAP48 RBBP4 RBBP7 RPD3L1 RXRA SAFA SLC25A7 SMAD1 SMAD4 SRC1 TXDI2 U21.1 UCP UCP1 ZNF423	Homo sapiens (human)
LXRs regulate gene expression to control bile acid homeostasis	Gastrotropin Nuclear receptor coactivator 1 Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 Oxysterols receptor LXR-alpha Oxysterols receptor LXR-beta Retinoic acid receptor RXR-alpha Retinoic acid receptor RXR-beta UDP-glucuronosyltransferase 1A3	O75376 P19793 P28702 P35503 P51161 P55055 Q13133 Q15788 Q9Y618	BHLHE74 CTG26 FABP6 GNT1 ILBP ILLBP KIAA1047 LXRA LXRB NCOA1 NCOR1 NCOR2 NER NR1H2 NR1H3 NR2B1 NR2B2 RXRA RXRB SRC1 UGT1 UGT1A3 UNR	Homo sapiens (human)
PTK6 promotes HIF1A stabilization	Epidermal growth factor receptor Hypoxia-inducible factor 1-alpha Leucine-rich repeat serine/threonine-protein kinase 2 Proheparin-binding EGF-like growth factor Protein-tyrosine kinase 6 Transmembrane glycoprotein NMB	P00533 Q13882 Q14956 Q16665 Q5S007 Q99075	BHLHE78 BRK DTR DTS EGFR ERBB ERBB1 GPNMB HBEGF HEGFL HER1 HGFIN HIF1A LRRK2 MOP1 NMB PARK8 PASD8 PTK6	Homo sapiens (human)
Activation of BID and translocation to mitochondria	BH3-interacting domain death agonist Caspase-8 Glycylpeptide N-tetradecanoyltransferase 1 Granzyme B	P10144 P30419 P55957 Q14790	BID CASP8 CGL1 CSPB CTLA1 GRB GZMB MCH5 NMT NMT1	Homo sapiens (human)
Zinc influx into cells by the SLC39 gene family	Metal cation symporter ZIP14 Metal cation symporter ZIP8 Zinc transporter SLC39A7 Zinc transporter ZIP10 Zinc transporter ZIP1 Zinc transporter ZIP2 Zinc transporter ZIP3 Zinc transporter ZIP4 Zinc transporter ZIP5 Zinc transporter ZIP6	Q13433 Q15043 Q6P5W5 Q6ZMH5 Q92504 Q9BRY0 Q9C0K1 Q9NP94 Q9NY26 Q9ULF5	BIGM103 HKE4 IRT1 KIAA0062 KIAA1265 LIV1 RING5 SLC39A1 SLC39A10 SLC39A14 SLC39A2 SLC39A3 SLC39A4 SLC39A5 SLC39A6 SLC39A7 SLC39A8 ZIP1 ZIP10 ZIP14 ZIP2 ZIP3 ZIP4 ZIP5 ZIP6 ZIP8 ZIRTL	Homo sapiens (human)
Signal regulatory protein family interactions	FYN-binding protein 1 Focal adhesion kinase 1 Leukocyte surface antigen CD47 Protein-tyrosine kinase 2-beta Signal-regulatory protein beta-1 Signal-regulatory protein gamma Src kinase-associated phosphoprotein 2 TYRO protein tyrosine kinase-binding protein Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6 Tyrosine-protein phosphatase non-receptor type substrate 1	O00241 O15117 O43914 O75563 P29350 P78324 Q05397 Q06124 Q08722 Q14289 Q9P1W8	BIT CD47 DAP12 FAK FAK1 FAK2 FYB FYB1 HCP KARAP MER6 MFR MYD1 PRAP PTK2 PTK2B PTP1C PTP2C PTPN11 PTPN6 PTPNS1 PYK2 RA70 RAFTK SAPS SCAP2 SHPS1 SHPTP2 SIRP SIRPA SIRPB1 SIRPB2 SIRPG SKAP2 SKAP55R SLAP130 TYROBP	Homo sapiens (human)
Intraflagellar transport	Clusterin-associated protein 1 Cytoplasmic dynein 2 heavy chain 1 Cytoplasmic dynein 2 intermediate chain 1 Cytoplasmic dynein 2 intermediate chain 2 Cytoplasmic dynein 2 light intermediate chain 1 Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic Dynein light chain Tctex-type 5 Dynein light chain Tctex-type protein 2 Dynein light chain Tctex-type protein 2B Dynein light chain roadblock-type 1 Dynein light chain roadblock-type 2 Intraflagellar transport protein 122 homolog Intraflagellar transport protein 140 homolog Intraflagellar transport protein 172 homolog Intraflagellar transport protein 20 homolog Intraflagellar transport protein 22 homolog Intraflagellar transport protein 25 homolog Intraflagellar transport protein 27 homolog Intraflagellar transport protein 43 homolog Intraflagellar transport protein 46 homolog Intraflagellar transport protein 52 homolog Intraflagellar transport protein 56 Intraflagellar transport protein 57 homolog Intraflagellar transport protein 70A Intraflagellar transport protein 70B Intraflagellar transport protein 74 homolog Intraflagellar transport protein 80 homolog Intraflagellar transport protein 81 homolog Intraflagellar transport protein 88 homolog Kinesin-associated protein 3 Kinesin-like protein KIF17 Kinesin-like protein KIF3A Kinesin-like protein KIF3B Kinesin-like protein KIF3C TRAF3-interacting protein 1 Tetratricopeptide repeat protein 21B Thyroid receptor-interacting protein 11 Transportin-1 WD repeat-containing protein 19 WD repeat-containing protein 35	A0AVF1 O14782 O15066 P63167 Q13099 Q15643 Q7Z4L5 Q86WT1 Q8IY31 Q8IZS6 Q8N4P2 Q8N7M0 Q8NCM8 Q8NEZ3 Q8TCX1 Q8TDR0 Q8TF09 Q8WVS4 Q8WW35 Q8WYA0 Q92845 Q92973 Q96AJ1 Q96EX3 Q96FJ2 Q96FT9 Q96LB3 Q96RY7 Q9BW83 Q9H7X7 Q9HBG6 Q9NP97 Q9NQC8 Q9NWB7 Q9P2E2 Q9P2H3 Q9P2L0 Q9UG01 Q9Y366 Q9Y496 Q9Y547	BITH C11orf2 C11orf60 C14orf179 C1orf41 C20orf9 CCDC2 CDV1 CEV14 CLUAP1 CMG1 D2LIC DERP8 DHC1B DHC2 DLC1 DLC2 DNCH2 DNCL1 DNCL2A DNCL2B DNCLC1 DNLC2A DNLC2B DYH1B DYNC2H1 DYNC2I1 DYNC2I2 DYNC2LI1 DYNLL1 DYNLL2 DYNLRB1 DYNLRB2 DYNLT2 DYNLT2B DYNLT5 ESRRBL1 HDLC1 HIPPI HSPB11 IFT121 IFT122 IFT139 IFT140 IFT144 IFT172 IFT20 IFT22 IFT25 IFT27 IFT43 IFT46 IFT52 IFT54 IFT56 IFT57 IFT70A IFT70B IFT74 IFT80 IFT81 IFT88 KIAA0359 KIAA0590 KIAA0643 KIAA1179 KIAA1336 KIAA1374 KIAA1405 KIAA1638 KIAA1992 KIAA1997 KIF17 KIF3 KIF3A KIF3AP KIF3B KIF3C KIF3X KIFAP3 KPNB2 LIC3 MIP1 MIPT3 NGD5 RABL4 RABL5 RAYL ROBLD1 ROBLD2 SMAP SPG TCTE3 TCTEX1D1 TCTEX1D2 TCTEX1D3 TG737 TNPO1 TRAF3IP1 TRIP11 TRN TTC10 TTC21B TTC26 TTC30A TTC30B WDR10 WDR140 WDR19 WDR34 WDR35 WDR56 WDR60 WDTC2	Homo sapiens (human)
Specification of primordial germ cells	Bone morphogenetic protein 4 C-X-C chemokine receptor type 4 Eomesodermin homolog Homeobox protein NANOG Methylcytosine dioxygenase TET2 Nanos homolog 3 POU domain, class 5, transcription factor 1 PR domain zinc finger protein 1 Podoplanin Protein CBFA2T2 Transcription factor AP-2 gamma Transcription factor SOX-17	O43439 O75626 O95936 P12644 P60323 P61073 Q01860 Q6N021 Q86YL7 Q92754 Q9H6I2 Q9H9S0	BLIMP1 BMP2B BMP4 CBFA2T2 CXCR4 DVR4 EHT EOMES GP36 KIAA1546 MTGR1 NANOG NANOS3 NOS3 OCT3 OCT4 OTF3 PDPN POU5F1 PRDM1 SOX17 TBR2 TET2 TFAP2C	Homo sapiens (human)
Regulation of TP53 Expression	Cellular tumor antigen p53 PR domain zinc finger protein 1	O75626 P04637	BLIMP1 P53 PRDM1 TP53	Homo sapiens (human)
Leukotriene receptors	Cysteinyl leukotriene receptor 1 Cysteinyl leukotriene receptor 2 Leukotriene B4 receptor 1 Leukotriene B4 receptor 2 Uracil nucleotide/cysteinyl leukotriene receptor	Q13304 Q15722 Q9NPC1 Q9NS75 Q9Y271	BLT BLT1 BLT2R BLTR BLTR2 CMKRL1 CYSLT1 CYSLT2 CYSLT2R CYSLTR1 CYSLTR2 GPR16 GPR17 LTB4R LTB4R2 P2RY7	Homo sapiens (human)
Interleukin-1 signaling	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-1 Dual specificity mitogen-activated protein kinase kinase 6 E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase pellino homolog 1 E3 ubiquitin-protein ligase pellino homolog 2 E3 ubiquitin-protein ligase pellino homolog 3 F-box/WD repeat-containing protein 1A Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 alpha Interleukin-1 beta Interleukin-1 receptor antagonist protein Interleukin-1 receptor type 1 Interleukin-1 receptor type 2 Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase 3 Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-associated kinase-like 2 Mitogen-activated protein kinase kinase kinase 3 Mitogen-activated protein kinase kinase kinase 7 Myeloid differentiation primary response protein MyD88 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Nucleoprotein Nucleotide-binding oligomerization domain-containing protein 1 Nucleotide-binding oligomerization domain-containing protein 2 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Receptor-interacting serine/threonine-protein kinase 2 S-phase kinase-associated protein 1 Sequestosome-1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 6 Toll-interacting protein Transcription factor p65 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O14920 O15111 O43187 O43242 O43318 O43353 O75832 P01583 P01584 P0CG47 P0CG48 P0DTC9 P14778 P17980 P18510 P19838 P20618 P25786 P25787 P25788 P25789 P25963 P27930 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51617 P51665 P52564 P55036 P60896 P60900 P61088 P61289 P62191 P62195 P62333 P62877 P62979 P62987 P63208 Q04206 Q06323 Q13200 Q13404 Q13501 Q13616 Q14997 Q15008 Q15750 Q16401 Q8N2H9 Q8N5C8 Q8TAA3 Q92530 Q96FA3 Q99436 Q99460 Q99759 Q99836 Q9H0E2 Q9HAT8 Q9HC29 Q9NWZ3 Q9NYJ8 Q9UL46 Q9UNM6 Q9Y239 Q9Y297 Q9Y4K3 Q9Y616 Q9Y6K9	BLU BTRC BTRCP C7orf76 CARD15 CARD4 CARDIAK CHUK CROC1 CUL1 DSS1 EMC19 FBW1A FBXW1A FIP3 HC2 HC3 HC8 HC9 HSPC IFI5111 IKBA IKBKB IKBKG IKKA IKKB IL1A IL1B IL1F1 IL1F2 IL1F3 IL1R IL1R1 IL1R2 IL1RA IL1RB IL1RN IL1RT1 IRAK IRAK1 IRAK2 IRAK3 IRAK4 KIAA0072 KIAA0077 KIAA0107 KIAA0733 LMP10 LMP2 LMP7 LMPX LMPY MAD3 MAP2K6 MAP3K3 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MAPKKK3 MB1 MCB1 MECL1 MEK6 MEKK3 MIP224 MKK6 MOV34L MSS1 MYD88 N NEMO NFKB1 NFKB3 NFKBI NFKBIA NOD1 NOD2 NU OCP2 ORCA OSIL PELI1 PELI2 PELI3 PFAAP4 POH1 PRISM PRKMK6 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RBX1 RELA RICK RING10 RING12 RIP2 RIPK2 RNF75 RNF85 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SKK3 SKP1 SKP1A SQSTM1 SUG1 SUG2 TAB1 TAB2 TAB3 TAK1 TBP1 TBP7 TCEB1L TCF16 TOLLIP TRAF6 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBE2N UBE2V UBE2V1 UEV1 X Y Y2 Z	Homo sapiens (human)
activated TAK1 mediates p38 MAPK activation	Dual specificity mitogen-activated protein kinase kinase 3 Dual specificity mitogen-activated protein kinase kinase 6 Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase-like 2 MAP kinase-activated protein kinase 2 MAP kinase-activated protein kinase 3 Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 14 Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator Nucleotide-binding oligomerization domain-containing protein 1 Nucleotide-binding oligomerization domain-containing protein 2 Receptor-interacting serine/threonine-protein kinase 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 6 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1	O43187 O43318 O43353 P46734 P49137 P51617 P52564 P61088 Q13404 Q15750 Q15759 Q16539 Q16644 Q8N5C8 Q9HC29 Q9NYJ8 Q9Y239 Q9Y4K3 Q9Y6K9	BLU CARD15 CARD4 CARDIAK CROC1 CSBP CSBP1 CSBP2 CSPB1 FIP3 IKBKG IRAK IRAK1 IRAK2 KIAA0733 MAP2K3 MAP2K6 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MAPK11 MAPK14 MAPKAPK2 MAPKAPK3 MEK3 MEK6 MKK3 MKK6 MXI2 NEMO NOD1 NOD2 PRKM11 PRKMK3 PRKMK6 RICK RIP2 RIPK2 RNF85 SAPK2 SAPK2A SAPK2B SKK2 SKK3 TAB1 TAB2 TAB3 TAK1 TRAF6 UBE2N UBE2V UBE2V1 UEV1	Homo sapiens (human)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1	Dual specificity mitogen-activated protein kinase kinase 4 Dual specificity mitogen-activated protein kinase kinase 7 Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase-like 2 Mitogen-activated protein kinase 10 Mitogen-activated protein kinase 8 Mitogen-activated protein kinase 9 Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator Nucleotide-binding oligomerization domain-containing protein 1 Nucleotide-binding oligomerization domain-containing protein 2 Receptor-interacting serine/threonine-protein kinase 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 6 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1	O14733 O43187 O43318 O43353 P45983 P45984 P45985 P51617 P53779 P61088 Q13404 Q15750 Q8N5C8 Q9HC29 Q9NYJ8 Q9Y239 Q9Y4K3 Q9Y6K9	BLU CARD15 CARD4 CARDIAK CROC1 FIP3 IKBKG IRAK IRAK1 IRAK2 JNK1 JNK2 JNK3 JNK3A JNKK1 JNKK2 KIAA0733 MAP2K4 MAP2K7 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MAPK10 MAPK8 MAPK9 MEK4 MEK7 MKK4 MKK7 NEMO NOD1 NOD2 PRKM10 PRKM8 PRKM9 PRKMK4 PRKMK7 RICK RIP2 RIPK2 RNF85 SAPK1 SAPK1A SAPK1B SAPK1C SEK1 SERK1 SKK1 SKK4 TAB1 TAB2 TAB3 TAK1 TRAF6 UBE2N UBE2V UBE2V1 UEV1	Homo sapiens (human)
IRAK1 recruits IKK complex	E3 ubiquitin-protein ligase pellino homolog 1 E3 ubiquitin-protein ligase pellino homolog 2 E3 ubiquitin-protein ligase pellino homolog 3 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 receptor-associated kinase 1 NF-kappa-B essential modulator TNF receptor-associated factor 6 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1	O14920 O15111 P51617 P61088 Q13404 Q8N2H9 Q96FA3 Q9HAT8 Q9Y4K3 Q9Y6K9	BLU CHUK CROC1 FIP3 IKBKB IKBKG IKKA IKKB IRAK IRAK1 NEMO PELI1 PELI2 PELI3 PRISM RNF85 TCF16 TRAF6 UBE2N UBE2V UBE2V1 UEV1	Homo sapiens (human)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation	E3 ubiquitin-protein ligase pellino homolog 1 E3 ubiquitin-protein ligase pellino homolog 2 E3 ubiquitin-protein ligase pellino homolog 3 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 receptor-associated kinase 1 NF-kappa-B essential modulator TNF receptor-associated factor 6 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1	O14920 O15111 P51617 P61088 Q13404 Q8N2H9 Q96FA3 Q9HAT8 Q9Y4K3 Q9Y6K9	BLU CHUK CROC1 FIP3 IKBKB IKBKG IKKA IKKB IRAK IRAK1 NEMO PELI1 PELI2 PELI3 PRISM RNF85 TCF16 TRAF6 UBE2N UBE2V UBE2V1 UEV1	Homo sapiens (human)

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