GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1876 - 1900** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼	Organism	GlyTouCan ID
Defective ABCG8 causes GBD4 and sitosterolemia	ATP-binding cassette sub-family G member 5 ATP-binding cassette sub-family G member 8	Q9H221 Q9H222	ABCG5 ABCG8	Homo sapiens (human)
Defective ABCG5 causes sitosterolemia	ATP-binding cassette sub-family G member 5 ATP-binding cassette sub-family G member 8	Q9H221 Q9H222	ABCG5 ABCG8	Homo sapiens (human)
Ciprofloxacin ADME	Albumin Broad substrate specificity ATP-binding cassette transporter ABCG2 Organic anion transporter 3 Solute carrier family 22 member 1 Solute carrier organic anion transporter family member 1A2	O15245 P02768 P46721 Q8TCC7 Q9UNQ0	ABCG2 ABCP ALB BCRP BCRP1 MXR OAT3 OATP OATP1 OATP1A2 OCT1 SLC21A3 SLC22A1 SLC22A8 SLCO1A2	Homo sapiens (human)
Heme biosynthesis	5-aminolevulinate synthase, erythroid-specific, mitochondrial 5-aminolevulinate synthase, non-specific, mitochondrial Albumin Broad substrate specificity ATP-binding cassette transporter ABCG2 Delta-aminolevulinic acid dehydratase Ferrochelatase, mitochondrial Heme A synthase COX15 Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial Porphobilinogen deaminase Protoheme IX farnesyltransferase, mitochondrial Protoporphyrinogen oxidase Uroporphyrinogen decarboxylase Uroporphyrinogen-III synthase	P02768 P06132 P08397 P10746 P13196 P13716 P22557 P22830 P36551 P50336 Q12887 Q7KZN9 Q9UNQ0	ABCG2 ABCP ALAD ALAS1 ALAS2 ALAS3 ALASE ALASH ALB ASB BCRP BCRP1 COX10 COX15 CPO CPOX CPX FECH HMBS MXR PBGD PPOX UPS UROD UROS	Homo sapiens (human)
Iron uptake and transport	Broad substrate specificity ATP-binding cassette transporter ABCG2 Ceruloplasmin Cullin-1 Cullin-associated NEDD8-dissociated protein 1 Cytoplasmic aconitate hydratase F-box/LRR-repeat protein 5 Ferritin heavy chain Ferritin light chain Ferritin, mitochondrial Glutaredoxin-3 Heme oxygenase 1 Heme oxygenase 2 Hephaestin Iron-responsive element-binding protein 2 NEDD8 Natural resistance-associated macrophage protein 2 Neutrophil gelatinase-associated lipocalin Plasma membrane ascorbate-dependent reductase CYBRD1 Polyubiquitin-B Polyubiquitin-C Proton-coupled folate transporter S-phase kinase-associated protein 1 Serotransferrin Solute carrier family 22 member 17 Solute carrier family 40 member 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O76003 P00450 P02787 P02792 P02794 P09601 P0CG47 P0CG48 P21399 P30519 P48200 P49281 P62979 P62987 P63208 P80188 Q13616 Q15843 Q53TN4 Q86VP6 Q8N4E7 Q8WUG5 Q96NT5 Q9BQS7 Q9NP59 Q9UKA1 Q9UNQ0	ABCG2 ABCP ACO1 BCRP BCRP1 BOCT BOIT CAND1 CP CUL1 CYBRD1 DCT1 DCYTB DMT1 EMC19 FBL4 FBL5 FBXL5 FLR1 FPN FPN1 FRRS3 FTH FTH1 FTHL6 FTL FTMT G21 GLRX3 HCP1 HEPH HMOX1 HMOX2 HNL HO HO1 HO2 IREB1 IREB2 IREG1 KIAA0698 KIAA0829 LCN2 MXR NEDD8 NGAL NRAMP2 OCP2 PCFT PICOT RPS27A SKP1 SKP1A SLC11A2 SLC11A3 SLC22A17 SLC40A1 SLC46A1 TCEB1L TF TIP120 TIP120A TXNL2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
OAS antiviral response	2',5'-phosphodiesterase 12 2'-5'-oligoadenylate synthase 1 2'-5'-oligoadenylate synthase 2 2'-5'-oligoadenylate synthase 3 2'-5'-oligoadenylate synthase-like protein 2-5A-dependent ribonuclease ATP-binding cassette sub-family E member 1 Antiviral innate immune response receptor RIG-I Filamin-A Protein VP3	B1NKT1 O95786 P00973 P21333 P29728 P61221 Q05823 Q15646 Q6L8Q7 Q9Y6K5	ABCE1 DDX58 FLN FLN1 FLNA OAS1 OAS2 OAS3 OASL OIAS PDE12 RIGI RLI RNASEL RNASEL1 RNASELI RNS4 RNS4I TRIP14	Homo sapiens (human)
Interferon alpha/beta signaling	2'-5'-oligoadenylate synthase 1 2'-5'-oligoadenylate synthase 2 2'-5'-oligoadenylate synthase 3 2'-5'-oligoadenylate synthase-like protein 2-5A-dependent ribonuclease ATP-binding cassette sub-family E member 1 Bone marrow stromal antigen 2 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Double-stranded RNA-specific adenosine deaminase Early growth response protein 1 Guanylate-binding protein 2 HLA class I histocompatibility antigen, A alpha chain HLA class I histocompatibility antigen, B alpha chain HLA class I histocompatibility antigen, C alpha chain HLA class I histocompatibility antigen, alpha chain E HLA class I histocompatibility antigen, alpha chain F HLA class I histocompatibility antigen, alpha chain G Importin subunit alpha-5 Importin subunit beta-1 Inositol hexakisphosphate kinase 2 Interferon alpha-1/13 Interferon alpha-10 Interferon alpha-14 Interferon alpha-16 Interferon alpha-17 Interferon alpha-21 Interferon alpha-2 Interferon alpha-4 Interferon alpha-5 Interferon alpha-6 Interferon alpha-7 Interferon alpha-8 Interferon alpha-inducible protein 27, mitochondrial Interferon alpha-inducible protein 6 Interferon alpha/beta receptor 1 Interferon beta Interferon regulatory factor 1 Interferon regulatory factor 2 Interferon regulatory factor 3 Interferon regulatory factor 4 Interferon regulatory factor 5 Interferon regulatory factor 6 Interferon regulatory factor 7 Interferon regulatory factor 8 Interferon regulatory factor 9 Interferon-induced 35 kDa protein Interferon-induced GTP-binding protein Mx1 Interferon-induced GTP-binding protein Mx2 Interferon-induced protein with tetratricopeptide repeats 1 Interferon-induced protein with tetratricopeptide repeats 2 Interferon-induced protein with tetratricopeptide repeats 3 Interferon-induced protein with tetratricopeptide repeats 5 Interferon-induced transmembrane protein 1 Interferon-induced transmembrane protein 2 Interferon-induced transmembrane protein 3 Interferon-induced, double-stranded RNA-activated protein kinase Interferon-stimulated gene 20 kDa protein Non-receptor tyrosine-protein kinase TYK2 Nucleoprotein Polyubiquitin-B Polyubiquitin-C Proteasome subunit beta type-8 Putative HLA class I histocompatibility antigen, alpha chain H S-adenosylmethionine-dependent nucleotide dehydratase RSAD2 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 2 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK1 Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6 Ubiquitin-like protein ISG15 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein XIAP-associated factor 1	O14543 O14879 O14896 O15524 P00973 P01562 P01563 P01566 P01567 P01568 P01569 P01570 P01571 P01574 P01889 P01893 P04439 P05013 P05014 P05015 P05161 P09912 P09913 P09914 P0CG47 P0CG48 P0DTC9 P10321 P10914 P13164 P13747 P14316 P17181 P17693 P18146 P19525 P20591 P20592 P23458 P28062 P29350 P29597 P29728 P30511 P32456 P32881 P40305 P42224 P52294 P52630 P55265 P61221 P62979 P62987 P80217 Q00978 Q01628 Q01629 Q02556 Q05823 Q06124 Q10589 Q13325 Q13568 Q14653 Q14974 Q15306 Q15646 Q6GPH4 Q8WXG1 Q92985 Q96AZ6 Q9UHH9 Q9Y3Z3 Q9Y6K5	ABCE1 ADAR ADAR1 BIRC4BP BST2 CD225 CIG-42 CIG-49 CIG5 CIS3 DSRAD EGR1 EIF2AK2 G10P1 G10P2 G1P1 G1P2 G1P3 GBP2 HCP HEM45 HLA-5.4 HLA-6.0 HLA-6.2 HLA-A HLA-B HLA-C HLA-E HLA-F HLA-G HLA-H HLAA HLAB HLAC HLAE HLAF HLAG HLAH ICSBP1 IFB IFI17 IFI27 IFI35 IFI4 IFI54 IFI56 IFI6 IFI60 IFIT1 IFIT2 IFIT3 IFIT4 IFIT5 IFITM1 IFITM2 IFITM3 IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA2A IFNA2B IFNA2C IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNAI1 IFNAR IFNAR1 IFNB IFNB1 IFP35 IHPK2 IP6K2 IRF1 IRF2 IRF3 IRF4 IRF5 IRF6 IRF7 IRF8 IRF9 ISG15 ISG20 ISG54 ISG56 ISG58 ISG60 ISGF3G JAK1 JAK1A JAK1B KPNA1 KPNB1 KROX24 LMP7 MOP5 MUM1 MX1 MX2 N NTF97 OAS1 OAS2 OAS3 OASL OIAS PKR PRKR PSMB5i PSMB8 PTP1C PTP2C PTPN11 PTPN6 RCH2 RI58 RING10 RLI RNASEL RNASEL1 RNASELI RNS4 RNS4I RPS27A RSAD2 SAMHD1 SHPTP2 SOCS1 SOCS3 SSI1 SSI3 STAT1 STAT2 TIP3 TRIP14 TYK2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UCRP XAF1 XIAPAF1 Y2 ZNF225	Homo sapiens (human)
Defective ABCD4 causes MAHCJ	Lysosomal cobalamin transport escort protein LMBD1 Lysosomal cobalamin transporter ABCD4	O14678 Q9NUN5	ABCD4 C6orf209 LMBRD1 NESI PXMP1L	Homo sapiens (human)
Uptake of dietary cobalamins into enterocytes	Chymotrypsinogen B2 Chymotrypsinogen B Cobalamin binding intrinsic factor Cubilin Lysosomal cobalamin transport escort protein LMBD1 Lysosomal cobalamin transporter ABCD4 Protein amnionless Serine protease 1 Transcobalamin-1 Trypsin-3	O14678 O60494 P07477 P17538 P20061 P27352 P35030 Q6GPI1 Q9BXJ7 Q9NUN5	ABCD4 AMN C6orf209 CBLIF CTRB CTRB1 CTRB2 CUBN GIF IFCR IFMH LMBRD1 NESI PRSS1 PRSS3 PRSS4 PXMP1L TC1 TCN1 TRP1 TRY1 TRY3 TRY4 TRYP1	Homo sapiens (human)
RHOC GTPase cycle	A-kinase anchor protein 13 ATP-binding cassette sub-family D member 3 Active breakpoint cluster region-related protein Acyl-CoA-binding domain-containing protein 5 Anillin Breakpoint cluster region protein Caveolae-associated protein 1 Caveolin-1 Cell surface glycoprotein MUC18 Citron Rho-interacting kinase Coiled-coil domain-containing protein 187 Complement component 1 Q subcomponent-binding protein, mitochondrial DEP domain-containing protein 1B Delta(14)-sterol reductase LBR Disheveled-associated activator of morphogenesis 1 Erbin Flotillin-1 Flotillin-2 Formin-like protein 2 Formin-like protein 3 Guanine nucleotide exchange factor DBS Guanine nucleotide exchange factor VAV2 Junction plakoglobin Lamina-associated polypeptide 2, isoforms beta/gamma Macoilin Oligophrenin-1 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Phosphatidylinositol 3-kinase regulatory subunit alpha Protein ERGIC-53 Protein diaphanous homolog 1 Protein diaphanous homolog 3 Proto-oncogene DBL Rac GTPase-activating protein 1 Ras GTPase-activating-like protein IQGAP1 Ras GTPase-activating-like protein IQGAP3 Rho GDP-dissociation inhibitor 1 Rho GTPase-activating protein 18 Rho GTPase-activating protein 1 Rho GTPase-activating protein 21 Rho GTPase-activating protein 26 Rho GTPase-activating protein 32 Rho GTPase-activating protein 35 Rho GTPase-activating protein 39 Rho GTPase-activating protein 5 Rho GTPase-activating protein 7 Rho guanine nucleotide exchange factor 10-like protein Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 28 Rho guanine nucleotide exchange factor 40 Rho guanine nucleotide exchange factor 5 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Rho-related GTP-binding protein RhoC Rhotekin STE20-like serine/threonine-protein kinase Serine/threonine-protein kinase 10 Serine/threonine-protein kinase N1 Serine/threonine-protein kinase N2 Serine/threonine-protein kinase N3 StAR-related lipid transfer protein 13 Stomatin Syntaxin-5 Tight junction protein ZO-2 Transferrin receptor protein 1 Transforming protein RhoA Unconventional myosin-IXb Vang-like protein 1 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein-associated protein B/C	A0A096LP49 A7KAX9 O14578 O15013 O15068 O15085 O60610 O60890 O75116 O75955 O94804 O95292 P02786 P08134 P10911 P11274 P14923 P27105 P27986 P28288 P42167 P43121 P46940 P49257 P52565 P52735 P61586 Q03135 Q07021 Q07960 Q12774 Q12802 Q12979 Q13017 Q13190 Q13459 Q13464 Q14254 Q14739 Q15836 Q16512 Q16513 Q5T5U3 Q5T8D3 Q6NZI2 Q6P5Z2 Q86VI3 Q86VW2 Q8IVF7 Q8N1W1 Q8N392 Q8N5G2 Q8TAA9 Q8TCU6 Q8TER5 Q8WUY9 Q92888 Q96PE2 Q96PY5 Q96QB1 Q96RT1 Q9BST9 Q9C0H5 Q9H0H5 Q9H2G2 Q9HCE6 Q9NQW6 Q9NRY4 Q9NSV4 Q9NZN5 Q9UDY2 Q9UNA1 Q9Y3M8 Q9Y4D1	ABCD3 ABR ACBD5 AKAP13 ANLN ARH12 ARH9 ARHA ARHC ARHGAP1 ARHGAP10 ARHGAP18 ARHGAP21 ARHGAP26 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP5 ARHGAP7 ARHGDIA ARHGEF1 ARHGEF10 ARHGEF10L ARHGEF11 ARHGEF12 ARHGEF17 ARHGEF25 ARHGEF28 ARHGEF40 ARHGEF5 BCR BCR1 BND7 BRX C1QBP CAV CAV1 CAVIN1 CCDC187 CDC42GAP CIT CRIK CTNNG D22S11 DAAM1 DBL DEPDC1B DIAP1 DIAP3 DIAPH1 DIAPH3 DLC1 DLC2 DP3 EPB72 ERBB2IP ERBIN ERGIC53 ESA1 F5F8D FHOD2 FHOD3 FLOT1 FLOT2 FMNL2 FMNL3 FRL2 GC1QBP GDIA1 GEFT GRAF GRB1 GRF1 GRINCHGEF GRIT GRLF1 GT650 HABP1 HT31 IQGAP1 IQGAP3 JUP KIAA0051 KIAA0204 KIAA0294 KIAA0337 KIAA0362 KIAA0380 KIAA0382 KIAA0619 KIAA0621 KIAA0666 KIAA0712 KIAA0949 KIAA1225 KIAA1415 KIAA1424 KIAA1478 KIAA1626 KIAA1688 KIAA1722 KIAA1723 KIAA1902 KIAA1996 KIAA1998 KIAA2014 LAP2 LARG LBC LBR LMAN1 LOK M17S1 MACO1 MCAM MCF2 MCF2L MGCRACGAP MUC18 MYO9B MYR5 OPHN1 OPHN1L OST P190A PAK1 PIK3R1 PKN PKN1 PKN2 PKN3 PKNBETA PMP70 PREX1 PRK1 PRK2 PRKCL1 PRKCL2 PTRF PXMP1 RACGAP1 RGNEF RHO12 RHOA RHOC RHOGAP1 RHOGAP5 RICS ROCK1 ROCK2 RTKN RTKN1 SF2P32 SLK SOLO STARD12 STARD13 STB2 STK10 STK2 STK21 STOM STX5 STX5A SYB3 TEM4 TFRC TIM TJP2 TMEM57 TMPO VAMP3 VANGL1 VAPB VAV2 WBP3 X104 XTP8 ZO2 p190ARHOGAP	Homo sapiens (human)
Defective ABCD1 causes ALD	ATP-binding cassette sub-family D member 1	P33897	ABCD1 ALD	Homo sapiens (human)
Linoleic acid (LA) metabolism	ATP-binding cassette sub-family D member 1 Acyl-CoA (8-3)-desaturase Acyl-CoA 6-desaturase Long-chain-fatty-acid--CoA ligase 1 Very long chain fatty acid elongase 1 Very long chain fatty acid elongase 2 Very long chain fatty acid elongase 3 Very long chain fatty acid elongase 5	O60427 O95864 P33121 P33897 Q9BW60 Q9HB03 Q9NXB9 Q9NYP7	ABCD1 ACSL1 ALD CIG30 ELG3 ELOVL1 ELOVL2 ELOVL3 ELOVL5 FACL1 FACL2 FADS1 FADS2 FADSD5 LACS LACS1 LACS2 SSC1 SSC2	Homo sapiens (human)
alpha-linolenic acid (ALA) metabolism	3-ketoacyl-CoA thiolase, peroxisomal ATP-binding cassette sub-family D member 1 Acyl-CoA (8-3)-desaturase Acyl-CoA 6-desaturase Acyl-coenzyme A thioesterase 8 Long-chain-fatty-acid--CoA ligase 1 Peroxisomal multifunctional enzyme type 2 Sterol carrier protein 2 Very long chain fatty acid elongase 1 Very long chain fatty acid elongase 2 Very long chain fatty acid elongase 3 Very long chain fatty acid elongase 5	O14734 O60427 O95864 P09110 P22307 P33121 P33897 P51659 Q9BW60 Q9HB03 Q9NXB9 Q9NYP7	ABCD1 ACAA ACAA1 ACOT8 ACSL1 ACTEIII ALD CIG30 EDH17B4 ELG3 ELOVL1 ELOVL2 ELOVL3 ELOVL5 FACL1 FACL2 FADS1 FADS2 FADSD5 HSD17B4 LACS LACS1 LACS2 PTE1 PTHIO SCP2 SDR8C1 SSC1 SSC2	Homo sapiens (human)
Beta-oxidation of very long chain fatty acids	3-ketoacyl-CoA thiolase, peroxisomal ATP-binding cassette sub-family D member 1 Acyl-coenzyme A thioesterase 6 Acyl-coenzyme A thioesterase 8 Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] Peroxisomal bifunctional enzyme Peroxisomal multifunctional enzyme type 2 Peroxisomal succinyl-coenzyme A thioesterase	O14734 P09110 P33897 P51659 Q08426 Q3I5F7 Q8N9L9 Q9NUI1	ABCD1 ACAA ACAA1 ACOT4 ACOT6 ACOT8 ACTEIII ALD C14orf42 DECR2 ECHD EDH17B4 EHHADH HSD17B4 PDCR PTE1 PTE2B PTEIB PTHIO SDR17C1 SDR8C1	Homo sapiens (human)
Class I peroxisomal membrane protein import	ATP-binding cassette sub-family D member 1 ATP-binding cassette sub-family D member 2 ATP-binding cassette sub-family D member 3 Acyl-CoA-binding domain-containing protein 5 Ganglioside-induced differentiation-associated protein 1 Mitochondrial fission 1 protein Outer mitochondrial transmembrane helix translocase Peroxisomal biogenesis factor 19 Peroxisomal biogenesis factor 3 Peroxisomal membrane protein 11B Peroxisomal membrane protein 2 Peroxisomal membrane protein 4 Peroxisomal membrane protein PEX13 Peroxisomal membrane protein PEX14 Peroxisomal membrane protein PEX16 Peroxisomal membrane protein PMP34 Peroxisome assembly protein 12 Peroxisome assembly protein 26 Peroxisome biogenesis factor 2	O00623 O43808 O75381 O96011 P28288 P28328 P33897 P40855 P56589 Q5T8D3 Q7Z412 Q8NBU5 Q8TB36 Q92968 Q9NR77 Q9UBJ2 Q9Y3D6 Q9Y5Y5 Q9Y6I8	ABCD1 ABCD2 ABCD3 ACBD5 ALD ALD1 ALDL1 ALDR ALDRP ATAD1 FIS1 GDAP1 HK33 KIAA1996 PAF1 PAF3 PEX11B PEX12 PEX13 PEX14 PEX16 PEX19 PEX2 PEX26 PEX3 PMP22 PMP24 PMP3 PMP34 PMP35 PMP70 PXF PXMP1 PXMP2 PXMP3 PXMP4 RNF72 SLC25A17 TTC11	Homo sapiens (human)
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome	ATP-binding cassette sub-family C member 9 ATP-sensitive inward rectifier potassium channel 11	O60706 Q14654	ABCC9 KCNJ11 SUR2	Homo sapiens (human)
Ion homeostasis	ATP-binding cassette sub-family C member 9 ATP-sensitive inward rectifier potassium channel 11 Aspartyl/asparaginyl beta-hydroxylase Calcium release-activated calcium channel protein 1 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Cardiac phospholamban Chloride intracellular channel protein 2 FXYD domain-containing ion transport regulator 3 FXYD domain-containing ion transport regulator 4 FXYD domain-containing ion transport regulator 6 FXYD domain-containing ion transport regulator 7 Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Myotonin-protein kinase Nitric oxide synthase 1 Peptidyl-prolyl cis-trans isomerase FKBP1B Phospholemman Plasma membrane calcium-transporting ATPase 1 Plasma membrane calcium-transporting ATPase 2 Plasma membrane calcium-transporting ATPase 3 Plasma membrane calcium-transporting ATPase 4 Protein orai-2 Ryanodine receptor 1 Ryanodine receptor 2 Ryanodine receptor 3 S-adenosylhomocysteine hydrolase-like protein 1 Sarcolipin Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 Short transient receptor potential channel 1 Sodium/calcium exchanger 1 Sodium/calcium exchanger 2 Sodium/calcium exchanger 3 Sodium/potassium-transporting ATPase subunit alpha-1 Sodium/potassium-transporting ATPase subunit alpha-2 Sodium/potassium-transporting ATPase subunit alpha-3 Sodium/potassium-transporting ATPase subunit alpha-4 Sodium/potassium-transporting ATPase subunit beta-1 Sodium/potassium-transporting ATPase subunit beta-2 Sodium/potassium-transporting ATPase subunit beta-3 Sodium/potassium-transporting ATPase subunit gamma Sorcin Stromal interaction molecule 1 Triadin Troponin I, cardiac muscle cAMP-dependent protein kinase catalytic subunit alpha	O00168 O00631 O14983 O15247 O43865 O60706 P05023 P05026 P0DP23 P13637 P14415 P16615 P17612 P19429 P20020 P21817 P23634 P26678 P29475 P30626 P32418 P48995 P50993 P54709 P54710 P57103 P58549 P59646 P68106 Q01814 Q09013 Q12797 Q13061 Q13554 Q13555 Q13557 Q13586 Q13733 Q14571 Q14573 Q14643 Q14654 Q14802 Q15413 Q16720 Q92736 Q93084 Q96D31 Q96SN7 Q9H0Q3 Q9UPR5 Q9UQM7	ABCC9 AHCYL1 ASPH ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1AL2 ATP1B ATP1B1 ATP1B2 ATP1B3 ATP1C ATP1G1 ATP2A1 ATP2A2 ATP2A3 ATP2B ATP2B1 ATP2B2 ATP2B3 ATP2B4 BAH C7orf19 CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CBCIP2 CLIC2 CNC CRACM1 DCAL DM1PK DMPK FKBP12.6 FKBP1B FKBP1L FKBP9 FXYD1 FXYD2 FXYD3 FXYD4 FXYD6 FXYD7 GOK HBRR INSP3R1 IRBIT ITPR1 ITPR2 ITPR3 KCNJ11 KIAA0778 KIAA0968 KIAA1087 MAT8 MDPK MXRA1 NCX1 NCX2 NCX3 NOS1 ORAI1 ORAI2 OTK4 PKACA PLB PLM PLML PLN PMCA1 PMCA2 PRKACA RYDR RYR1 RYR2 RYR3 SLC8A1 SLC8A2 SLC8A3 SLN SRI STIM1 SUR2 TMEM142A TMEM142B TNNC1 TNNI3 TRDN TRP1 TRPC1 XPVKONA	Homo sapiens (human)
Defective ABCC8 can cause hypo- and hyper-glycemias	ATP-binding cassette sub-family C member 8 ATP-sensitive inward rectifier potassium channel 11	Q09428 Q14654	ABCC8 HRINS KCNJ11 SUR SUR1	Homo sapiens (human)
Regulation of insulin secretion	ATP-binding cassette sub-family C member 8 ATP-sensitive inward rectifier potassium channel 11 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Insulin Rap guanine nucleotide exchange factor 3 Rap guanine nucleotide exchange factor 4 S-adenosylhomocysteine hydrolase-like protein 1 Solute carrier family 2, facilitated glucose transporter member 1 Solute carrier family 2, facilitated glucose transporter member 2 Synaptosomal-associated protein 25 Synaptotagmin-5 Syntaxin-1A Syntaxin-binding protein 1 Vesicle-associated membrane protein 2 Voltage-dependent L-type calcium channel subunit alpha-1C Voltage-dependent L-type calcium channel subunit alpha-1D Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent L-type calcium channel subunit beta-3 Voltage-dependent P/Q-type calcium channel subunit alpha-1A Voltage-dependent R-type calcium channel subunit alpha-1E Voltage-dependent calcium channel subunit alpha-2/delta-2 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	O00445 O00555 O43865 O95398 P01308 P04899 P11166 P11168 P17612 P22612 P22694 P54284 P60880 P61764 P63027 P63096 Q01668 Q08289 Q09428 Q13936 Q14571 Q14573 Q14643 Q14654 Q15878 Q16623 Q8WZA2 Q9NY47	ABCC8 AHCYL1 CACH2 CACH3 CACH4 CACH6 CACN2 CACN3 CACN4 CACNA1A CACNA1C CACNA1D CACNA1E CACNA2D2 CACNB2 CACNB3 CACNL1A1 CACNL1A2 CACNL1A4 CACNL1A6 CACNLB2 CACNLB3 CCHL1A1 CCHL1A2 CGEF1 CGEF2 DCAL EPAC EPAC1 EPAC2 GLUT1 GLUT2 GNAI1 GNAI2 GNAI2B HRINS INS INSP3R1 IRBIT ITPR1 ITPR2 ITPR3 KCNJ11 KIAA0558 MYSB PKACA PRKACA PRKACB PRKACG RAPGEF3 RAPGEF4 SLC2A1 SLC2A2 SNAP SNAP25 STX1 STX1A STXBP1 SUR SUR1 SYB2 SYT5 UNC18A VAMP2 XPVKONA	Homo sapiens (human)	G58161NS
ATP sensitive Potassium channels	ATP-binding cassette sub-family C member 8 ATP-binding cassette sub-family C member 9 ATP-sensitive inward rectifier potassium channel 11 ATP-sensitive inward rectifier potassium channel 8	O60706 Q09428 Q14654 Q15842	ABCC8 ABCC9 HRINS KCNJ11 KCNJ8 SUR SUR1 SUR2	Homo sapiens (human)
Defective CFTR causes cystic fibrosis	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cystic fibrosis transmembrane conductance regulator Derlin-1 Derlin-2 Derlin-3 E3 ubiquitin-protein ligase RNF185 E3 ubiquitin-protein ligase RNF5 Endoplasmic reticulum lectin 1 Erlin-1 Erlin-2 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein OS-9 Protein sel-1 homolog 1 Transitional endoplasmic reticulum ATPase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O43242 O75477 O75832 O94905 P0CG47 P0CG48 P13569 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P55072 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q06323 Q13200 Q13438 Q14997 Q15008 Q16401 Q8TAA3 Q92530 Q96DZ1 Q96GF1 Q96Q80 Q99436 Q99460 Q99942 Q9BUN8 Q9GZP9 Q9UBV2 Q9UL46 Q9UNM6	ABCC7 C10orf69 C22orf14 C2orf30 C7orf76 C8orf2 CFTR DER1 DER2 DER3 DERL1 DERL2 DERL3 DSS1 ERLEC1 ERLIN1 ERLIN2 FLANA G16 HC2 HC3 HC8 HC9 HEL-220 HEL-S-70 HSPC IFI5111 KE04 KEO4 KIAA0072 KIAA0077 KIAA0107 LLN2 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NG2 NU OS9 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RING10 RING12 RMA1 RNF185 RNF5 RPS27A SEL1L SEM1 SHFDG1 SHFM1 SPFH1 SPFH2 SUG1 SUG2 TBP1 TBP7 TRAP2 TSA305 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VCP X XTP3TPB Y Y2 Z	Homo sapiens (human)
Aggrephagy	ADP-ribosylation factor-like protein 13B Centrin-1 Cystic fibrosis transmembrane conductance regulator Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic E3 ubiquitin-protein ligase parkin Heat shock factor protein 1 Heat shock protein HSP 90-alpha Histone deacetylase 6 Intraflagellar transport protein 88 homolog Parkinson disease protein 7 Pericentrin Polyubiquitin-B Polyubiquitin-C Transitional endoplasmic reticulum ATPase Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14576 O43237 O60260 O95613 P07900 P0CG47 P0CG48 P13569 P55072 P61088 P62979 P62987 P63167 Q00613 Q12798 Q13099 Q13404 Q13409 Q14204 Q3SXY8 Q96FJ2 Q99497 Q9UBN7 Q9Y6G9	ABCC7 ARL13B ARL2L1 BLU CEN1 CETN CETN1 CFTR CROC1 DHC1 DLC1 DLC2 DNCH1 DNCI1 DNCI2 DNCIC1 DNCIC2 DNCL DNCL1 DNCLC1 DNCLI1 DNCLI2 DNECL DYHC DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 HDAC6 HDLC1 HEL-220 HEL-S-70 HSF1 HSP90A HSP90AA1 HSPC1 HSPCA HSTF1 IFT88 KIAA0325 KIAA0402 KIAA0901 LIC2 PARK2 PARK7 PCNT PCNT2 PRKN RPS27A TG737 TTC10 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBE2N UBE2V UBE2V1 UEV1 VCP	Homo sapiens (human)
RHO GTPases regulate CFTR trafficking	Cystic fibrosis transmembrane conductance regulator Golgi-associated PDZ and coiled-coil motif-containing protein Rho-related GTP-binding protein RhoQ	P13569 P17081 Q9HD26	ABCC7 ARHQ CAL CFTR FIG GOPC RASL7A RHOQ TC10	Homo sapiens (human)
RHOQ GTPase cycle	ADP-ribosylation factor-like protein 13B ARF GTPase-activating protein GIT1 ARF GTPase-activating protein GIT2 Actin nucleation-promoting factor WASL Caveolin-1 Cdc42 effector protein 1 Cdc42 effector protein 2 Cdc42 effector protein 3 Cdc42 effector protein 4 Cdc42-interacting protein 4 Cell division control protein 42 homolog Copine-8 Cystic fibrosis transmembrane conductance regulator DEP domain-containing protein 1B Formin-binding protein 1 Gap junction alpha-1 protein Glucose-fructose oxidoreductase domain-containing protein 1 Golgi-associated PDZ and coiled-coil motif-containing protein Intersectin-1 Junction plakoglobin MAGUK p55 subfamily member 7 Metalloreductase STEAP3 NEDD4-like E3 ubiquitin-protein ligase WWP2 Neutral amino acid transporter B(0) Obscurin Oligophrenin-1 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Pleckstrin homology domain-containing family G member 3 Protein diaphanous homolog 3 Protein scribble homolog Ragulator complex protein LAMTOR1 Ras GTPase-activating-like protein IQGAP1 Ras GTPase-activating-like protein IQGAP3 Ras-related protein Rab-7a Rho GTPase-activating protein 17 Rho GTPase-activating protein 1 Rho GTPase-activating protein 21 Rho GTPase-activating protein 26 Rho GTPase-activating protein 32 Rho GTPase-activating protein 33 Rho GTPase-activating protein 35 Rho GTPase-activating protein 5 Rho GTPase-activating protein 7 Rho GTPase-activating protein SYDE1 Rho guanine nucleotide exchange factor 7 Rho guanine nucleotide exchange factor 9 Rho-related GTP-binding protein RhoQ SLIT-ROBO Rho GTPase-activating protein 2 Serine/threonine-protein kinase MRCK alpha Serine/threonine-protein kinase MRCK beta Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 4 Sodium bicarbonate cotransporter 3 Stomatin Synaptosomal-associated protein 23 Transferrin receptor protein 1 Vang-like protein 1 Vesicle-associated membrane protein 3	A1L390 A7KAX9 O00161 O00308 O00401 O14559 O14613 O43307 O60890 O75044 O96013 P02786 P13569 P14923 P17081 P17302 P27105 P46940 P51149 P60953 Q00587 Q03135 Q07960 Q13017 Q13153 Q13177 Q14155 Q14160 Q14161 Q15642 Q15758 Q15811 Q15836 Q3SXY8 Q5T2T1 Q5T5U3 Q5VST9 Q5VT25 Q658P3 Q68EM7 Q6IAA8 Q6ZW31 Q86VI3 Q86YQ8 Q8TAA9 Q8TCU6 Q8WUY9 Q96QB1 Q96RU3 Q9H3Q1 Q9HD26 Q9NRY4 Q9NSV4 Q9NXC2 Q9UKI2 Q9UNA1 Q9Y2X7 Q9Y5S2 Q9Y6M7	ABCC7 ARHDH9 ARHGAP1 ARHGAP10 ARHGAP17 ARHGAP21 ARHGAP26 ARHGAP32 ARHGAP33 ARHGAP34 ARHGAP35 ARHGAP5 ARHGAP7 ARHGEF7 ARHGEF9 ARHQ ARL13B ARL2L1 ASCT2 BND7 BORG1 BORG2 BORG4 BORG5 BT C11orf59 C6orf114 CAL CAV CAV1 CDC42 CDC42BPA CDC42BPB CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 CDC42GAP CEP1 CEP2 CEP3 CEP4 CFTR CIP4 COOL1 CPNE8 CRIB1 CTNNG DEPDC1B DIAP3 DIAPH3 DLC1 DP3 EPB72 FBP17 FIG FNBP1 FNBP2 GFOD1 GIT1 GIT2 GJA1 GJAL GOPC GRAF GRF1 GRIT GRLF1 IQGAP1 IQGAP3 ITSN ITSN1 JUP KIAA0051 KIAA0142 KIAA0147 KIAA0148 KIAA0424 KIAA0451 KIAA0456 KIAA0554 KIAA0599 KIAA0621 KIAA0712 KIAA1124 KIAA1142 KIAA1415 KIAA1424 KIAA1556 KIAA1639 KIAA1722 KIAA1723 LAMTOR1 LAP4 M7V1 MPP7 MSE55 NBC2 NBC2B NBC3 NBCn1 OBSCN OPHN1 OPHN1L P190A P85SPR PAK1 PAK2 PAK3BP PAK4 PDRO PIXB PLEKHG3 PREX1 RAB7 RAB7A RASL7A RDR RDRC RHOGAP1 RHOGAP5 RHOQ RICH1 RICS SBC2 SCRB1 SCRIB SH3D1A SLC1A5 SLC4A6 SLC4A7 SNAP23 SNX26 SRGAP2 SRGAP2A STARD12 STB2 STEAP3 STOM STOT STP SYB3 SYDE1 TC10 TCGAP TFRC TRIP10 TSAP6 VAMP3 VANGL1 VARTUL WASL WWP2 XTP8 p190ARHOGAP	Homo sapiens (human)
Chaperone Mediated Autophagy	ADP-ribosylation factor-like protein 13B Centrin-1 Cystic fibrosis transmembrane conductance regulator Elongation factor 1-alpha 1 Glial fibrillary acidic protein Heat shock cognate 71 kDa protein Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Hemoglobin subunit beta Histone deacetylase 6 Intraflagellar transport protein 88 homolog Lysosome-associated membrane glycoprotein 2 Parkinson disease protein 7 Pericentrin Perilipin-2 Perilipin-3 Polyubiquitin-B Polyubiquitin-C Ribonuclease pancreatic Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O60664 O95613 P07900 P07998 P08238 P0CG47 P0CG48 P11142 P13473 P13569 P14136 P62979 P62987 P68104 P68871 Q12798 Q13099 Q3SXY8 Q99497 Q99541 Q9UBN7	ABCC7 ADFP ARL13B ARL2L1 CEN1 CETN CETN1 CFTR EEF1A EEF1A1 EF1A GFAP HBB HDAC6 HSC70 HSP73 HSP90A HSP90AA1 HSP90AB1 HSP90B HSPA10 HSPA8 HSPC1 HSPC2 HSPC3 HSPCA HSPCB IFT88 KIAA0402 KIAA0901 LAMP2 LENG7 M6PRBP1 PARK7 PCNT PCNT2 PLIN2 PLIN3 RIB1 RNASE1 RNS1 RPS27A TG737 TIP47 TTC10 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)

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