GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1926 - 1950** of **2090** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol	Organism
KEAP1-NFE2L2 pathway	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 APC membrane recruitment protein 1 Breast cancer type 1 susceptibility protein Casein kinase II subunit alpha' Casein kinase II subunit alpha Casein kinase II subunit beta Cullin-3 Cyclin-dependent kinase inhibitor 1 Dipeptidyl peptidase 3 E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase TRIM21 Eukaryotic translation initiation factor 2-alpha kinase 3 Kelch-like ECH-associated protein 1 Microtubule-associated proteins 1A/1B light chain 3B Mitochondrial ubiquitin ligase activator of NFKB 1 Nuclear factor erythroid 2-related factor 2 Nuclear protein localization protein 4 homolog Partner and localizer of BRCA2 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein X Protein kinase C delta type Protein kinase C iota type RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Sequestosome-1 Sestrin-1 Sestrin-2 Transitional endoplasmic reticulum ATPase UBX domain-containing protein 7 Ubiquitin recognition factor in ER-associated degradation protein 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O43242 O75832 O94888 P0CG47 P0CG48 P17980 P19474 P19784 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P31749 P31751 P35998 P38398 P38936 P40306 P41743 P43686 P48556 P49720 P49721 P51665 P55036 P55072 P58004 P60896 P60900 P61289 P62191 P62195 P62333 P62877 P62979 P62987 P67870 P68400 Q05655 Q06323 Q13200 Q13501 Q13618 Q14145 Q14997 Q15008 Q16236 Q16401 Q2F514 Q5JTC6 Q86YC2 Q8TAA3 Q8TAT6 Q92530 Q92890 Q969V5 Q99436 Q99460 Q9GZQ8 Q9NY33 Q9NZJ5 Q9UL46 Q9UNM6 Q9Y243 Q9Y6P5	AKT1 AKT2 AKT3 AMER1 BRCA1 C1orf166 C7orf76 CAP20 CDKN1 CDKN1A CIP1 CK2A1 CK2A2 CK2N CSNK2A1 CSNK2A2 CSNK2B CUL3 DPP3 DSS1 DXS1179E EIF2AK3 FAM123B FANCN G5A GIDE HC2 HC3 HC8 HC9 HEL-220 HEL-S-70 HSPC Hi95 IFI5111 INRF2 KEAP1 KIAA0072 KIAA0077 KIAA0107 KIAA0132 KIAA0617 KIAA0794 KIAA1499 KLHL19 LMP10 LMP2 LMP7 LMPX LMPY MAP1ALC3 MAP1LC3B MAPL MB1 MCB1 MDA6 MECL1 MIP224 MOV34L MSS1 MUL1 MULAN NFE2L2 NPL4 NPLOC4 NRF2 NU ORCA OSIL PA26 PALB2 PEK PERK PFAAP4 PIC1 PKB PKBG PKCD POH1 PRKCD PRKCI PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RAC RBX1 RING10 RING12 RNF218 RNF53 RNF75 RNF81 RO52 ROC1 RPS27A SDI1 SEM1 SESN1 SESN2 SEST1 SEST2 SHFDG1 SHFM1 SQSTM1 SSA1 SUG1 SUG2 TBP1 TBP7 TRAP2 TRIM21 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBXD7 UBXN7 UFD1 UFD1L VCP WAF1 WTX X Y Y2 Z x	Homo sapiens (human)
Neddylation	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 APC membrane recruitment protein 1 Ankyrin repeat and SOCS box protein 10 Ankyrin repeat and SOCS box protein 11 Ankyrin repeat and SOCS box protein 12 Ankyrin repeat and SOCS box protein 13 Ankyrin repeat and SOCS box protein 14 Ankyrin repeat and SOCS box protein 15 Ankyrin repeat and SOCS box protein 16 Ankyrin repeat and SOCS box protein 17 Ankyrin repeat and SOCS box protein 18 Ankyrin repeat and SOCS box protein 1 Ankyrin repeat and SOCS box protein 2 Ankyrin repeat and SOCS box protein 3 Ankyrin repeat and SOCS box protein 4 Ankyrin repeat and SOCS box protein 5 Ankyrin repeat and SOCS box protein 6 Ankyrin repeat and SOCS box protein 7 Ankyrin repeat and SOCS box protein 8 Ankyrin repeat and SOCS box protein 9 Ankyrin repeat domain-containing protein 9 BTB/POZ domain-containing protein 1 BTB/POZ domain-containing protein 6 BTB/POZ domain-containing protein KCTD6 BTB/POZ domain-containing protein KCTD7 Baculoviral IAP repeat-containing protein 5 Breast cancer type 1 susceptibility protein COMM domain-containing protein 10 COMM domain-containing protein 1 COMM domain-containing protein 2 COMM domain-containing protein 3 COMM domain-containing protein 4 COMM domain-containing protein 5 COMM domain-containing protein 6 COMM domain-containing protein 7 COMM domain-containing protein 8 COMM domain-containing protein 9 COP9 signalosome complex subunit 1 COP9 signalosome complex subunit 2 COP9 signalosome complex subunit 3 COP9 signalosome complex subunit 4 COP9 signalosome complex subunit 5 COP9 signalosome complex subunit 6 COP9 signalosome complex subunit 7a COP9 signalosome complex subunit 7b COP9 signalosome complex subunit 8 Coiled-coil domain-containing protein 22 Coiled-coil domain-containing protein 8 Cullin-1 Cullin-2 Cullin-3 Cullin-4A Cullin-4B Cullin-5 Cullin-7 Cullin-9 Cullin-associated NEDD8-dissociated protein 1 Cyclin-F Cyclin-dependent kinase inhibitor 1 Cytokine-inducible SH2-containing protein DCN1-like protein 1 DCN1-like protein 2 DCN1-like protein 3 DCN1-like protein 4 DCN1-like protein 5 DDB1- and CUL4-associated factor 10 DDB1- and CUL4-associated factor 11 DDB1- and CUL4-associated factor 13 DDB1- and CUL4-associated factor 16 DDB1- and CUL4-associated factor 17 DDB1- and CUL4-associated factor 4 DDB1- and CUL4-associated factor 5 DDB1- and CUL4-associated factor 6 DDB1- and CUL4-associated factor 7 DDB1- and CUL4-associated factor 8 DET1- and DDB1-associated protein 1 DNA damage-binding protein 1 DNA damage-binding protein 2 DNA excision repair protein ERCC-8 Denticleless protein homolog Dipeptidyl peptidase 3 E3 ubiquitin-protein ligase COP1 E3 ubiquitin-protein ligase RBX1 Elongin-B Elongin-C Endothelial PAS domain-containing protein 1 F-box and leucine-rich protein 22 F-box and leucine-rich repeat protein 13 F-box only protein 10 F-box only protein 11 F-box only protein 15 F-box only protein 17 F-box only protein 21 F-box only protein 22 F-box only protein 27 F-box only protein 2 F-box only protein 30 F-box only protein 31 F-box only protein 32 F-box only protein 40 F-box only protein 41 F-box only protein 44 F-box only protein 4 F-box only protein 6 F-box only protein 7 F-box only protein 9 F-box/LRR-repeat protein 12 F-box/LRR-repeat protein 14 F-box/LRR-repeat protein 15 F-box/LRR-repeat protein 16 F-box/LRR-repeat protein 18 F-box/LRR-repeat protein 19 F-box/LRR-repeat protein 20 F-box/LRR-repeat protein 3 F-box/LRR-repeat protein 4 F-box/LRR-repeat protein 5 F-box/LRR-repeat protein 7 F-box/LRR-repeat protein 8 F-box/WD repeat-containing protein 10 F-box/WD repeat-containing protein 11 F-box/WD repeat-containing protein 12 F-box/WD repeat-containing protein 1A F-box/WD repeat-containing protein 2 F-box/WD repeat-containing protein 4 F-box/WD repeat-containing protein 5 F-box/WD repeat-containing protein 7 F-box/WD repeat-containing protein 8 F-box/WD repeat-containing protein 9 Gigaxonin Histone-binding protein RBBP7 Hypoxia-inducible factor 1-alpha Hypoxia-inducible factor 3-alpha Kelch repeat and BTB domain-containing protein 13 Kelch repeat and BTB domain-containing protein 6 Kelch repeat and BTB domain-containing protein 7 Kelch repeat and BTB domain-containing protein 8 Kelch-like ECH-associated protein 1 Kelch-like protein 11 Kelch-like protein 13 Kelch-like protein 20 Kelch-like protein 21 Kelch-like protein 22 Kelch-like protein 25 Kelch-like protein 2 Kelch-like protein 3 Kelch-like protein 41 Kelch-like protein 42 Kelch-like protein 5 Kelch-like protein 9 LIM domain only protein 7 Leucine-rich repeat protein 1 Leucine-rich repeat-containing protein 41 Mitochondrial ubiquitin ligase activator of NFKB 1 NEDD8-activating enzyme E1 catalytic subunit NEDD8-activating enzyme E1 regulatory subunit NEDD8-conjugating enzyme UBE2F NEDD8-conjugating enzyme Ubc12 NEDD8 Neuralized-like protein 2 Nuclear factor erythroid 2-related factor 2 Nuclear protein localization protein 4 homolog Obscurin-like protein 1 Partner and localizer of BRCA2 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein X Protein fem-1 homolog A Protein fem-1 homolog B Protein fem-1 homolog C Pumilio homolog 2 Putative F-box/LRR-repeat protein 21 RING-box protein 2 Retinoblastoma-binding protein 5 S-phase kinase-associated protein 1 S-phase kinase-associated protein 2 SPRY domain-containing SOCS box protein 1 SPRY domain-containing SOCS box protein 2 SPRY domain-containing SOCS box protein 3 SPRY domain-containing SOCS box protein 4 Sentrin-specific protease 8 Sequestosome-1 Suppressor of cytokine signaling 2 Suppressor of cytokine signaling 3 Suppressor of cytokine signaling 5 Suppressor of cytokine signaling 6 Transitional endoplasmic reticulum ATPase Tubby-related protein 4 UBX domain-containing protein 7 Ubiquitin D Ubiquitin carboxyl-terminal hydrolase isozyme L3 Ubiquitin recognition factor in ER-associated degradation protein 1 Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein WD and tetratricopeptide repeats protein 1 WD repeat and SOCS box-containing protein 1 WD repeat and SOCS box-containing protein 2 WD repeat-containing protein 5 Zinc finger and BTB domain-containing protein 16 von Hippel-Lindau disease tumor suppressor	A5LHX3 A6NK59 C9JR72 O00231 O00232 O00233 O00487 O14508 O14543 O14544 O14818 O15205 O15392 O43242 O60662 O60826 O75147 O75159 O75832 O94888 O94952 O95198 P0CG47 P0CG48 P15374 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P38398 P38936 P40306 P40337 P41002 P43686 P48556 P49720 P49721 P51665 P51668 P55036 P55072 P57775 P60896 P60900 P61077 P61081 P61201 P61289 P61962 P61964 P62191 P62195 P62333 P62837 P62877 P62979 P62987 P63208 Q05516 Q06323 Q13098 Q13200 Q13216 Q13309 Q13501 Q13564 Q13616 Q13617 Q13618 Q13619 Q13620 Q14145 Q14997 Q14999 Q15008 Q15291 Q15345 Q15369 Q15370 Q15843 Q16236 Q16401 Q16531 Q16576 Q16665 Q2F514 Q53GT1 Q58WW2 Q5H9S7 Q5JTC6 Q5QP82 Q5TAQ9 Q5XUX0 Q5XUX1 Q5XX13 Q6P050 Q6PCT2 Q6PH85 Q6PJ21 Q6X9E4 Q6ZVZ8 Q7L5N1 Q7Z4G1 Q86V97 Q86VP6 Q86VX2 Q86X83 Q86XK2 Q86YC2 Q8IWE4 Q8IWT3 Q8N1E6 Q8N3Y1 Q8N461 Q8N5D0 Q8N668 Q8NC69 Q8NCQ5 Q8NEE6 Q8NEZ5 Q8NFY9 Q8NHY2 Q8NI29 Q8TAA3 Q8TAT6 Q8TB52 Q8TB72 Q8TBC4 Q8TEB1 Q8TF61 Q8WV16 Q8WVZ9 Q8WWI1 Q8WWX0 Q8WXH4 Q8WXI3 Q8WXJ9 Q8WXK1 Q8WXK3 Q8WXK4 Q92466 Q92530 Q92564 Q92890 Q92905 Q93034 Q969H0 Q969M7 Q969P5 Q969U6 Q969V5 Q96A44 Q96BD6 Q96BM1 Q96CD0 Q96DX5 Q96EF6 Q96GG9 Q96IG2 Q96JK2 Q96JP0 Q96KE9 Q96L50 Q96LD8 Q96ME1 Q96MP8 Q96NS5 Q96PQ7 Q96Q27 Q99436 Q99460 Q99619 Q99627 Q99814 Q9BR09 Q9BSK4 Q9BT78 Q9BTE7 Q9BW61 Q9GZQ3 Q9H0A8 Q9H0C5 Q9H0H3 Q9H0W5 Q9H2C0 Q9H469 Q9H4M3 Q9H672 Q9H765 Q9H9Q2 Q9NRD1 Q9NRJ4 Q9NSE2 Q9NV06 Q9NVR0 Q9NWX5 Q9NX08 Q9NXF7 Q9NXK8 Q9NY33 Q9NYS7 Q9NZJ0 Q9P000 Q9P2J3 Q9P2K6 Q9P2N7 Q9UBF6 Q9UBI1 Q9UBW8 Q9UH77 Q9UH90 Q9UJP4 Q9UJT9 Q9UK22 Q9UK73 Q9UK96 Q9UK97 Q9UKA1 Q9UKA2 Q9UKB1 Q9UKT5 Q9UKT6 Q9UKT7 Q9UKT8 Q9UL46 Q9UNM6 Q9UNS2 Q9Y297 Q9Y2M5 Q9Y2N7 Q9Y3I1 Q9Y574 Q9Y575 Q9Y576 Q9Y6G5 Q9Y6I7	AMER1 ANKRD9 API4 APPBP1 ASB1 ASB10 ASB11 ASB12 ASB13 ASB14 ASB15 ASB16 ASB17 ASB18 ASB2 ASB3 ASB4 ASB5 ASB6 ASB7 ASB8 ASB9 BCRG2 BDPL BHLHE17 BHLHE73 BHLHE78 BIG3 BIRC5 BKLHD2 BRCA1 BTBD1 BTBD6 BTRC BTRCP BTRCP2 BUP C10orf8 C13orf17 C15orf1 C16orf22 C16orf31 C19orf58 C1orf166 C20orf163 C20orf92 C2orf37 C2orf5 C4orf30 C7orf76 CAND1 CAP20 CCDC22 CCDC8 CCNF CDKN1 CDKN1A CDT2 CDW1 CIP1 CIS2 CIS3 CIS4 CIS6 CISH CISH5 CISH6 CKN1 COMMD1 COMMD10 COMMD2 COMMD3 COMMD4 COMMD5 COMMD6 COMMD7 COMMD8 COMMD9 COP1 COPS1 COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A COPS7B COPS8 CSA CSN1 CSN2 CSN3 CSN4 CSN5 CSN6 CSN7A CSN7B CSN8 CUL1 CUL2 CUL3 CUL4A CUL4B CUL5 CUL7 CUL9 CXorf37 DCAF10 DCAF11 DCAF13 DCAF16 DCAF17 DCAF2 DCAF4 DCAF5 DCAF6 DCAF7 DCAF8 DCN1 DCUN1D1 DCUN1D2 DCUN1D3 DCUN1D4 DCUN1D5 DCUN1L1 DCUN1L2 DDA1 DDB1 DDB2 DEN1 DERP10 DPP3 DRC6 DSS1 DTL ELOB ELOC EMC19 ENC2 EPAS1 EPRAP ERCC8 F1AA FAM123B FANCN FAT10 FBG2 FBG3 FBG4 FBG5 FBL12 FBL13 FBL14 FBL16 FBL18 FBL19 FBL2 FBL21 FBL3 FBL3A FBL4 FBL5 FBL6 FBL7 FBL8 FBS2 FBW12 FBW1A FBW1B FBW2 FBW4 FBW5 FBW6 FBW7 FBW8 FBW9 FBX1 FBX10 FBX11 FBX14 FBX15 FBX17 FBX2 FBX20 FBX21 FBX22 FBX26 FBX27 FBX29 FBX30 FBX31 FBX4 FBX40 FBX41 FBX44 FBX6 FBX6A FBX7 FBX9 FBXL1 FBXL12 FBXL13 FBXL14 FBXL15 FBXL16 FBXL18 FBXL19 FBXL20 FBXL21 FBXL21P FBXL22 FBXL3 FBXL3A FBXL3B FBXL3P FBXL4 FBXL5 FBXL7 FBXL8 FBXO1 FBXO10 FBXO11 FBXO12 FBXO15 FBXO17 FBXO2 FBXO20 FBXO21 FBXO22 FBXO26 FBXO27 FBXO29 FBXO30 FBXO31 FBXO32 FBXO35 FBXO37 FBXO4 FBXO40 FBXO41 FBXO44 FBXO6 FBXO6A FBXO7 FBXO9 FBXW10 FBXW11 FBXW12 FBXW1A FBXW1B FBXW2 FBXW4 FBXW5 FBXW6 FBXW7 FBXW8 FBXW9 FEM1A FEM1B FEM1C FLR1 FWD2 G18 GAN GAN1 GIDE GPS1 GRCC9 H326 H7AP1 HAN11 HC2 HC3 HC8 HC9 HEL-220 HEL-S-70 HIF1A HIF2A HIF3A HSPC HVIP IAP4 IFI5111 INRF2 IQWD1 JAB1 KBTBD10 KBTBD13 KBTBD6 KBTBD7 KBTBD8 KCTD6 KCTD7 KEAP1 KIAA0072 KIAA0076 KIAA0077 KIAA0107 KIAA0132 KIAA0235 KIAA0276 KIAA0396 KIAA0469 KIAA0617 KIAA0657 KIAA0671 KIAA0695 KIAA0696 KIAA0708 KIAA0794 KIAA0829 KIAA0840 KIAA0858 KIAA0875 KIAA1037 KIAA1129 KIAA1146 KIAA1195 KIAA1309 KIAA1340 KIAA1354 KIAA1397 KIAA1499 KIAA1785 KIAA1824 KIAA1842 KIAA1940 KLEIP KLHDC5 KLHL11 KLHL13 KLHL16 KLHL19 KLHL2 KLHL20 KLHL21 KLHL22 KLHL25 KLHL3 KLHL41 KLHL42 KLHL5 KLHL9 KLHLX KRP1 L2DTL LMO7 LMP10 LMP2 LMP7 LMPX LMPY LRR1 LRRC41 MAPL MB1 MCB1 MDA6 MECL1 MIP224 MOP1 MOP2 MOP7 MOV34L MSS1 MUF1 MUL1 MULAN MURR1 NAE1 NCE2 NEDD8 NEDP1 NEURL2 NFE2L2 NPL4 NPLOC4 NRF2 NS5ATP8 NU OBSL1 OCP2 ORCA OSIL PALB2 PARC PASD2 PASD7 PASD8 PCIA1 PFAAP4 PIC1 PLZF POH1 PPIL5 PRMT11 PRMT9 PROS26 PROS27 PROS30 PRSC2 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 PUBC1 PUM2 PUMH2 RAMP RBAP46 RBBP5 RBBP7 RBQ3 RBX1 RBX2 RFWD2 RING10 RING12 RNF200 RNF218 RNF53 RNF7 RNF75 ROC1 ROC2 RP42 RPS27A SAG SCCRO SCCRO3 SCCRO5 SDI1 SEL10 SEM1 SENP8 SFT SHFDG1 SHFM1 SHFM3 SKP1 SKP1A SKP2 SOCS2 SOCS3 SOCS4 SOCS5 SOCS6 SPSB1 SPSB2 SPSB3 SPSB4 SQSTM1 SSB1 SSB2 SSB3 SSB4 SSI2 SSI3 STATI2 SUG1 SUG2 SWIP1 TAKRP TBP1 TBP7 TCEB1 TCEB1L TCEB2 TIP120 TIP120A TRAP2 TRIP15 TUBL4 TULP4 TUSP UBA3 UBA52 UBA80 UBB UBC UBC12 UBC4 UBC5A UBC5B UBC5C UBCEP1 UBCEP2 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBD UBE1C UBE2D1 UBE2D2 UBE2D3 UBE2F UBE2M UBXD7 UBXN7 UCHL3 UFD1 UFD1L VACM1 VCIA1 VCP VHL VIT1 WAF1 WDR21 WDR21A WDR22 WDR23 WDR32 WDR42A WDR5 WDR68 WDSOF1 WDTC1 WSB1 WSB2 WTX X XAP1 Y Y2 Z ZBTB16 ZNF145 x	Homo sapiens (human)
Degradation of beta-catenin by the destruction complex	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 APC membrane recruitment protein 1 Adenomatous polyposis coli protein Axin-1 Casein kinase I isoform alpha Catenin beta-1 Cullin-1 E3 ubiquitin-protein ligase RBX1 F-box/WD repeat-containing protein 1A Glycogen synthase kinase-3 beta Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 S-phase kinase-associated protein 1 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Ubiquitin thioesterase ZRANB1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O15169 O43242 O75832 P0CG47 P0CG48 P17980 P20618 P25054 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P30153 P30154 P35222 P35998 P40306 P43686 P48556 P48729 P49720 P49721 P49841 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62714 P62877 P62979 P62987 P63208 P67775 Q06323 Q13200 Q13362 Q13616 Q14738 Q14997 Q15008 Q15172 Q15173 Q16401 Q16537 Q5JTC6 Q8TAA3 Q92530 Q99436 Q99460 Q9UGI0 Q9UL46 Q9UNM6 Q9Y297	AMER1 APC AXIN AXIN1 BTRC BTRCP C7orf76 CSNK1A1 CTNNB CTNNB1 CUL1 DP2.5 DSS1 EMC19 FAM123B FBW1A FBXW1A GSK3B HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0044 KIAA0072 KIAA0077 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NU OCP2 PFAAP4 POH1 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RBX1 RING10 RING12 RNF75 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SUG1 SUG2 TBP1 TBP7 TCEB1L TRABID TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WTX X Y Y2 Z ZRANB1	Homo sapiens (human)
ABC-family proteins mediated transport	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 ABC-type oligopeptide transporter ABCB9 ABC-type organic anion transporter ABCA8 ATP-binding cassette sub-family B member 5 ATP-binding cassette sub-family C member 10 ATP-binding cassette sub-family C member 11 ATP-binding cassette sub-family C member 2 ATP-binding cassette sub-family C member 3 ATP-binding cassette sub-family C member 4 ATP-binding cassette sub-family C member 5 ATP-binding cassette sub-family C member 6 ATP-binding cassette sub-family C member 9 ATP-binding cassette sub-family F member 1 ATP-dependent translocase ABCB1 ATP-sensitive inward rectifier potassium channel 11 Cystic fibrosis transmembrane conductance regulator Derlin-1 Derlin-2 Derlin-3 E3 ubiquitin-protein ligase RNF185 E3 ubiquitin-protein ligase RNF5 Endoplasmic reticulum lectin 1 Erlin-1 Erlin-2 Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Multidrug resistance-associated protein 1 Phosphatidylcholine translocator ABCB4 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein OS-9 Protein sel-1 homolog 1 Retinal-specific phospholipid-transporting ATPase ABCA4 Transitional endoplasmic reticulum ATPase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O15438 O15439 O15440 O43242 O60706 O75477 O75832 O94905 O94911 O95255 P05198 P08183 P0CG47 P0CG48 P13569 P17980 P20042 P20618 P21439 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P33527 P35998 P40306 P41091 P43686 P48556 P49720 P49721 P51665 P55036 P55072 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 P78363 Q06323 Q13200 Q13438 Q14654 Q14997 Q15008 Q16401 Q2M3G0 Q5T3U5 Q8NE71 Q8TAA3 Q92530 Q92887 Q96DZ1 Q96GF1 Q96J66 Q96Q80 Q99436 Q99460 Q99942 Q9BUN8 Q9GZP9 Q9NP78 Q9UBV2 Q9UL46 Q9UNM6	ABC50 ABCA4 ABCA8 ABCB1 ABCB4 ABCB5 ABCB9 ABCC1 ABCC10 ABCC11 ABCC2 ABCC3 ABCC4 ABCC5 ABCC6 ABCC7 ABCC9 ABCF1 ABCR ARA C10orf69 C22orf14 C2orf30 C7orf76 C8orf2 CFTR CMOAT CMOAT1 CMOAT2 CMRP DER1 DER2 DER3 DERL1 DERL2 DERL3 DSS1 EIF2A EIF2B EIF2G EIF2S1 EIF2S2 EIF2S3 ERLEC1 ERLIN1 ERLIN2 FLANA G16 HC2 HC3 HC8 HC9 HEL-220 HEL-S-70 HSPC IFI5111 KCNJ11 KE04 KEO4 KIAA0072 KIAA0077 KIAA0107 KIAA0822 KIAA1520 LLN2 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MDR1 MDR3 MECL1 MIP224 MLP2 MOATB MOV34L MRP MRP1 MRP2 MRP3 MRP4 MRP5 MRP6 MRP7 MRP8 MSS1 NG2 NU OS9 PFAAP4 PGY1 PGY3 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RING10 RING12 RMA1 RNF185 RNF5 RPS27A SEL1L SEM1 SHFDG1 SHFM1 SIMRP7 SPFH1 SPFH2 SUG1 SUG2 SUR2 TBP1 TBP7 TRAP2 TSA305 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VCP X XTP3TPB Y Y2 Z	Homo sapiens (human)
FCERI mediated NF-kB activation	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 3-phosphoinositide-dependent protein kinase 1 B-cell lymphoma/leukemia 10 Caspase recruitment domain-containing protein 11 Cullin-1 F-box/WD repeat-containing protein 11 F-box/WD repeat-containing protein 1A IGHV7-81 protein Immunoglobulin heavy constant epsilon Immunoglobulin heavy variable 1-2 Immunoglobulin heavy variable 1-46 Immunoglobulin heavy variable 1-69 Immunoglobulin heavy variable 2-5 Immunoglobulin heavy variable 2-70 Immunoglobulin heavy variable 3-11 Immunoglobulin heavy variable 3-13 Immunoglobulin heavy variable 3-23 Immunoglobulin heavy variable 3-30 Immunoglobulin heavy variable 3-33 Immunoglobulin heavy variable 3-48 Immunoglobulin heavy variable 3-53 Immunoglobulin heavy variable 3-7 Immunoglobulin heavy variable 3-9 Immunoglobulin heavy variable 4-34 Immunoglobulin heavy variable 4-39 Immunoglobulin heavy variable 4-59 Immunoglobulin kappa constant Immunoglobulin kappa variable 1-12 Immunoglobulin kappa variable 1-16 Immunoglobulin kappa variable 1-17 Immunoglobulin kappa variable 1-33 Immunoglobulin kappa variable 1-39 Immunoglobulin kappa variable 1-5 Immunoglobulin kappa variable 1D-12 Immunoglobulin kappa variable 1D-16 Immunoglobulin kappa variable 1D-33 Immunoglobulin kappa variable 1D-39 Immunoglobulin kappa variable 2-28 Immunoglobulin kappa variable 2-29 Immunoglobulin kappa variable 2-30 Immunoglobulin kappa variable 2D-28 Immunoglobulin kappa variable 2D-30 Immunoglobulin kappa variable 2D-40 Immunoglobulin kappa variable 3-11 Immunoglobulin kappa variable 3-15 Immunoglobulin kappa variable 3-20 Immunoglobulin kappa variable 3D-20 Immunoglobulin kappa variable 4-1 Immunoglobulin kappa variable 5-2 Immunoglobulin lambda constant 1 Immunoglobulin lambda constant 2 Immunoglobulin lambda constant 3 Immunoglobulin lambda constant 6 Immunoglobulin lambda constant 7 Immunoglobulin lambda variable 1-40 Immunoglobulin lambda variable 1-44 Immunoglobulin lambda variable 1-47 Immunoglobulin lambda variable 1-51 Immunoglobulin lambda variable 2-11 Immunoglobulin lambda variable 2-14 Immunoglobulin lambda variable 2-23 Immunoglobulin lambda variable 2-8 Immunoglobulin lambda variable 3-19 Immunoglobulin lambda variable 3-1 Immunoglobulin lambda variable 3-21 Immunoglobulin lambda variable 3-25 Immunoglobulin lambda variable 3-27 Immunoglobulin lambda variable 6-57 Immunoglobulin lambda variable 7-43 Immunolglobulin kappa light chain variable region L22 (Fragment) Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Mitogen-activated protein kinase kinase kinase 7 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein kinase C theta type RAS guanyl-releasing protein 1 RAS guanyl-releasing protein 2 RAS guanyl-releasing protein 4 S-phase kinase-associated protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 6 Transcription factor p65 Tyrosine-protein kinase Lyn UGa8H (Fragment) Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 R1 Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein V1-11 protein (Fragment) V1-13 protein (Fragment) V1-16 protein (Fragment) V1-20 protein (Fragment) V1-3 protein (Fragment) V1-5 protein (Fragment) V1-7 protein (Fragment) V1-9 protein (Fragment) V2-11 protein (Fragment) V2-15 protein (Fragment) V2-17 protein (Fragment) V2-19 protein (Fragment) V2-8 protein (Fragment) V3-2 protein (Fragment) V3-3 protein (Fragment) V3-4 protein (Fragment) V4-1 protein (Fragment) V4-2 protein (Fragment) V4-6 protein (Fragment) V5-1 protein (Fragment) V5-4 protein (Fragment) V5-6 protein (Fragment)	A0A075B6P5 A0A075B6S6 A0A0C4DH25 A0A0C4DH73 A0M8Q6 A2KUC3 A2NJV5 A2NXD2 A5LHX3 O00231 O00232 O00233 O00487 O14818 O14920 O15111 O15530 O43242 O43318 O75832 O95267 O95999 P01593 P01594 P01597 P01599 P01601 P01602 P01611 P01614 P01615 P01619 P01624 P01699 P01700 P01701 P01703 P01704 P01705 P01706 P01709 P01714 P01715 P01717 P01718 P01721 P01742 P01743 P01762 P01763 P01764 P01766 P01767 P01768 P01772 P01780 P01782 P01814 P01817 P01824 P01825 P01834 P01854 P04211 P04430 P04432 P04433 P06310 P06312 P06315 P06331 P07948 P0CF74 P0CG04 P0CG47 P0CG48 P0DOY2 P0DOY3 P17980 P19838 P20618 P23083 P25786 P25787 P25788 P25789 P25963 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49427 P49720 P49721 P51665 P51668 P55036 P60896 P60900 P61088 P61289 P62191 P62195 P62333 P62837 P62979 P62987 P63208 P80748 Q04206 Q04759 Q06323 Q13200 Q13404 Q13616 Q14997 Q15008 Q15750 Q16401 Q5NV61 Q5NV62 Q5NV64 Q5NV65 Q5NV66 Q5NV67 Q5NV68 Q5NV69 Q5NV75 Q5NV79 Q5NV80 Q5NV81 Q5NV82 Q5NV83 Q5NV84 Q5NV85 Q5NV86 Q5NV87 Q5NV89 Q5NV90 Q5NV91 Q5NV92 Q6PIL0 Q7LDG7 Q8N5C8 Q8TAA3 Q8TDF6 Q92530 Q99436 Q99460 Q9BXL7 Q9NYJ8 Q9UDY8 Q9UKB1 Q9UL46 Q9UNM6 Q9Y297 Q9Y4K3 Q9Y6K9	BCL10 BLU BTRC BTRCP BTRCP2 C7orf76 CARD11 CARMA1 CDC25L CDC34 CHUK CIPER CLAP CROC1 CUL1 DSS1 EMC19 FBW1A FBW1B FBXW11 FBXW1A FBXW1B FIP3 HC2 HC3 HC8 HC9 HSPC IFI5111 IGHE IGHV IGHV1-2 IGHV1-46 IGHV1-69 IGHV2-5 IGHV2-70 IGHV3-11 IGHV3-13 IGHV3-23 IGHV3-30 IGHV3-33 IGHV3-48 IGHV3-53 IGHV3-7 IGHV3-9 IGHV4-34 IGHV4-39 IGHV4-59 IGHV7-81 IGKC IGKV1-12 IGKV1-16 IGKV1-17 IGKV1-33 IGKV1-39 IGKV1-5 IGKV1D-12 IGKV1D-16 IGKV1D-33 IGKV1D-39 IGKV2-28 IGKV2-29 IGKV2-30 IGKV2D-28 IGKV2D-30 IGKV2D-40 IGKV3-11 IGKV3-15 IGKV3-20 IGKV3D-20 IGKV4-1 IGKV5-2 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7 IGLV IGLV1-40 IGLV1-44 IGLV1-47 IGLV1-51 IGLV2-11 IGLV2-14 IGLV2-23 IGLV2-8 IGLV3-1 IGLV3-19 IGLV3-21 IGLV3-25 IGLV3-27 IGLV6-57 IGLV7-43 IKBA IKBKB IKBKG IKKA IKKB JTK8 KIAA0072 KIAA0077 KIAA0107 KIAA0696 KIAA0733 LMP10 LMP2 LMP7 LMPX LMPY LYN MAD3 MALT1 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MB1 MCB1 MCG7 MECL1 MIP224 MLT MOV34L MSS1 NEMO NFKB1 NFKB3 NFKBI NFKBIA NU OCP2 PDK1 PDPK1 PFAAP4 POH1 PRKCQ PRKCT PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 PUBC1 RASGRP RASGRP1 RASGRP2 RASGRP4 RELA RING10 RING12 RNF85 RPS27A SEM1 SFT SHFDG1 SHFM1 SKP1 SKP1A SUG1 SUG2 TAB1 TAB2 TAB3 TAK1 TBP1 TBP7 TCEB1L TCF16 TRAF6 TRAP2 UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBCEP1 UBCEP2 UBCH3 UBCH4 UBCH5 UBCH5A UBCH5B UBE2D1 UBE2D2 UBE2N UBE2R1 UBE2V UBE2V1 UEV1 V1-11 V1-13 V1-16 V1-20 V1-3 V1-5 V1-7 V1-9 V2-11 V2-15 V2-17 V2-19 V2-8 V3-2 V3-3 V3-4 V4-1 V4-2 V4-6 V5-1 V5-4 V5-6 X Y Y2 Z	Homo sapiens (human)
Downstream TCR signaling	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 3-phosphoinositide-dependent protein kinase 1 B-cell lymphoma/leukemia 10 Caspase recruitment domain-containing protein 11 Cullin-1 F-box/WD repeat-containing protein 11 F-box/WD repeat-containing protein 1A HLA class II histocompatibility antigen, DP alpha 1 chain HLA class II histocompatibility antigen, DP beta 1 chain HLA class II histocompatibility antigen, DQ alpha 1 chain HLA class II histocompatibility antigen, DQ alpha 2 chain HLA class II histocompatibility antigen, DQ beta 1 chain HLA class II histocompatibility antigen, DQ beta 2 chain HLA class II histocompatibility antigen, DR alpha chain HLA class II histocompatibility antigen, DR beta 3 chain HLA class II histocompatibility antigen, DR beta 4 chain HLA class II histocompatibility antigen, DR beta 5 chain HLA class II histocompatibility antigen, DRB1 beta chain Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Mitogen-activated protein kinase kinase kinase 7 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein kinase C theta type Receptor-interacting serine/threonine-protein kinase 2 S-phase kinase-associated protein 1 T cell receptor alpha chain constant T cell receptor alpha variable 19 T cell receptor alpha variable 29/delta variable 5 T cell receptor alpha variable 8-4 T cell receptor beta constant 1 T cell receptor beta variable 12-3 T cell receptor beta variable 7-9 T-cell receptor-associated transmembrane adapter 1 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD4 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TNF receptor-associated factor 6 Transcription factor p65 Tyrosine-protein kinase Lck Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 R1 Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A0A6YYK7 A5LHX3 O00231 O00232 O00233 O00459 O00487 O14818 O14920 O15111 O15530 O43242 O43318 O43353 O75832 O95999 P01730 P01733 P01737 P01848 P01850 P01903 P01906 P01909 P01911 P01920 P04234 P04435 P04437 P04440 P05538 P06239 P07766 P09693 P0CG47 P0CG48 P13762 P17980 P19838 P20036 P20618 P25786 P25787 P25788 P25789 P25963 P27986 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P42336 P42338 P43686 P48556 P49427 P49720 P49721 P51665 P51668 P55036 P60484 P60896 P60900 P61088 P61289 P62191 P62195 P62333 P62837 P62979 P62987 P63208 P79483 Q04206 Q04759 Q06323 Q13200 Q13404 Q13616 Q14997 Q15008 Q16401 Q30154 Q6PIZ9 Q8TAA3 Q92530 Q92835 Q99436 Q99460 Q9BXL7 Q9NYJ8 Q9UDY8 Q9UKB1 Q9UL46 Q9UNM6 Q9Y297 Q9Y4K3 Q9Y6K9	BCL10 BLU BTRC BTRCP BTRCP2 C7orf76 CARD11 CARDIAK CARMA1 CD3D CD3E CD3G CD4 CDC34 CHUK CIPER CLAP CROC1 CUL1 DSS1 EMC19 FBW1A FBW1B FBXW11 FBXW1A FBXW1B FIP3 GRB1 HC2 HC3 HC8 HC9 HLA-DP1A HLA-DP1B HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB HLA-DQB1 HLA-DQB2 HLA-DRA HLA-DRA1 HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 HLA-DXA HLA-DXB HLASB HSPC IFI5111 IKBA IKBKB IKBKG IKKA IKKB INPP5D KIAA0072 KIAA0077 KIAA0107 KIAA0696 KIAA0733 LCK LMP10 LMP2 LMP7 LMPX LMPY MAD3 MALT1 MAP3K7 MAP3K7IP2 MB1 MCB1 MECL1 MIP224 MLT MMAC1 MOV34L MSS1 NEMO NFKB1 NFKB3 NFKBI NFKBIA NU OCP2 PDK1 PDPK1 PFAAP4 PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 POH1 PRKCQ PRKCT PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 PTEN PUBC1 RELA RICK RING10 RING12 RIP2 RIPK2 RNF85 RPS27A SEM1 SFT SHFDG1 SHFM1 SHIP SHIP1 SKP1 SKP1A SUG1 SUG2 T3D T3E T3G TAB2 TAK1 TBP1 TBP7 TCEB1L TCF16 TCRA TCRBV12S3 TCRBV8S1 TCRIM TEP1 TRAC TRAF6 TRAP2 TRAT1 TRAV19 TRAV29DV5 TRAV8-4 TRBC1 TRBV12-3 TRBV7-9 UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBCEP1 UBCEP2 UBCH3 UBCH4 UBCH5 UBCH5A UBCH5B UBE2D1 UBE2D2 UBE2N UBE2R1 UBE2V UBE2V1 UEV1 X Y Y2 Z	Homo sapiens (human)
Endogenous sterols	24-hydroxycholesterol 7-alpha-hydroxylase Adrenodoxin, mitochondrial Aromatase Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Aryl hydrocarbon receptor repressor Aryl hydrocarbon receptor Bile acid receptor Cholesterol 24-hydroxylase Cholesterol side-chain cleavage enzyme, mitochondrial Cytochrome P450 11B1, mitochondrial Cytochrome P450 11B2, mitochondrial Cytochrome P450 1B1 Cytochrome P450 4V2 Cytochrome P450 7A1 Cytochrome P450 7B1 Ferredoxin-2, mitochondrial Lanosterol 14-alpha demethylase NADPH Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Pro-opiomelanocortin Retinoic acid receptor RXR-alpha Steroid 21-hydroxylase Sterol 26-hydroxylase, mitochondrial	A9YTQ3 O75881 P01189 P05108 P08686 P10109 P11511 P15538 P19099 P19793 P22570 P22680 P27540 P35869 Q02318 Q15596 Q15788 Q16678 Q16850 Q6P4F2 Q6ZWL3 Q96RI1 Q9HBZ2 Q9NYL5 Q9Y6A2	ADX ADXR AHR AHRR ARNT ARNT2 ARO1 BAR BHLHE1 BHLHE2 BHLHE74 BHLHE75 BHLHE76 BHLHE77 CYAR CYP11A CYP11A1 CYP11B1 CYP11B2 CYP19 CYP19A1 CYP1B1 CYP21 CYP21A2 CYP21B CYP27 CYP27A1 CYP39A1 CYP46 CYP46A1 CYP4V2 CYP51 CYP51A1 CYP7 CYP7A1 CYP7B1 FDX1 FDX1L FDX2 FDXR FXR HRR1 KIAA0307 KIAA1234 NCOA1 NCOA2 NR1H4 NR2B1 POMC RIP14 RXRA S11BH SRC1 SRC2 TIF2	Homo sapiens (human)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol	24-hydroxycholesterol 7-alpha-hydroxylase 3 beta-hydroxysteroid dehydrogenase type 7 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase Aldo-keto reductase family 1 member C1 Aldo-keto reductase family 1 member C2 Aldo-keto reductase family 1 member C3 Aldo-keto reductase family 1 member C4 Aldo-keto reductase family 1 member D1 Alpha-methylacyl-CoA racemase Cholesterol 24-hydroxylase Long-chain fatty acid transport protein 2 Long-chain fatty acid transport protein 5 Prostacyclin synthase Sterol 26-hydroxylase, mitochondrial	O14975 P17516 P42330 P51857 P52895 Q02318 Q04828 Q16647 Q9H2F3 Q9NYL5 Q9UHK6 Q9UNU6 Q9Y2P5 Q9Y6A2	ACSB ACSVL1 ACSVL6 AKR1C1 AKR1C2 AKR1C3 AKR1C4 AKR1D1 AMACR CHDR CYP12 CYP27 CYP27A1 CYP39A1 CYP46 CYP46A1 CYP8 CYP8A1 CYP8B1 DDH DDH1 DDH2 FACVL1 FACVL3 FATP2 FATP5 HSD17B5 HSD3B7 KIAA0119 PGFS PTGIS SLC27A2 SLC27A5 SRD5B1 VLACS	Homo sapiens (human)
Branched-chain amino acid catabolism	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial 3-hydroxyacyl-CoA dehydrogenase type-2 3-hydroxyisobutyrate dehydrogenase, mitochondrial 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial Acetyl-CoA acetyltransferase, mitochondrial Branched-chain alpha-ketoacid dehydrogenase kinase Branched-chain-amino-acid aminotransferase, cytosolic Branched-chain-amino-acid aminotransferase, mitochondrial Dihydrolipoyl dehydrogenase, mitochondrial Enoyl-CoA hydratase, mitochondrial Isobutyryl-CoA dehydrogenase, mitochondrial Isovaleryl-CoA dehydrogenase, mitochondrial Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial Methylglutaconyl-CoA hydratase, mitochondrial Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial Protein phosphatase Mn(2+)-dependent 1K Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial Solute carrier family 25 member 44	O14874 O15382 P09622 P11182 P12694 P21953 P24752 P26440 P30084 P31937 P45954 P54687 Q02252 Q13825 Q6NVY1 Q8N3J5 Q96H78 Q96RQ3 Q99714 Q9HCC0 Q9UKU7	ACAD8 ACADSB ACAT ACAT1 ALDH6A1 ARC42 AUH BCAT1 BCAT2 BCATE2 BCATM BCKDHA BCKDHB BCKDHE2 BCKDK BCT1 BCT2 DBT DLD ECA39 ECA40 ECHS1 ERAB GCSL HADH2 HIBADH HIBCH HSD17B10 IBD IVD KIAA0446 LAD MAT MCCA MCCB MCCC1 MCCC2 MMSDH MRPP2 PHE3 PP2CM PPM1K SCHAD SDR5C1 SLC25A44 XH98G2	Homo sapiens (human)
Class A/1 (Rhodopsin-like receptors)	2-oxoglutarate receptor 1 Cannabinoid receptor 1 Cannabinoid receptor 2 Chemerin-like receptor 1 G-protein coupled bile acid receptor 1 G-protein coupled receptor 183 G-protein coupled receptor 35 G-protein coupled receptor 39 G-protein coupled receptor 4 G-protein coupled receptor 55 Hydroxycarboxylic acid receptor 2 Melatonin receptor type 1A Melatonin receptor type 1B N-arachidonyl glycine receptor Ovarian cancer G-protein coupled receptor 1 Platelet-activating factor receptor Probable G-protein coupled receptor 132 Psychosine receptor Succinate receptor 1	O43194 P21554 P25105 P32249 P34972 P46093 P48039 P49286 Q14330 Q15743 Q8IYL9 Q8TDS4 Q8TDU6 Q96P68 Q99788 Q9BXA5 Q9HC97 Q9UNW8 Q9Y2T6	CB2A CB2B CHEMR23 CMKLR1 CNR CNR1 CNR2 DEZ EBI2 G2A GPBAR1 GPCRW GPR109A GPR132 GPR18 GPR183 GPR35 GPR39 GPR4 GPR55 GPR65 GPR68 GPR80 GPR91 GPR99 HCA2 HCAR2 HM74A MTNR1A MTNR1B NIACR1 OGR1 OXGR1 P2RY15 P2Y15 PAFR PTAFR SUCNR1 TDAG8 TGR5	Homo sapiens (human)
Succinyl-CoA Biosynthesis	2-oxoglutarate dehydrogenase complex component E1 Alpha-ketoglutarate dehydrogenase component 4 Dihydrolipoyl dehydrogenase, mitochondrial Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial	P09622 P36957 P82909 Q02218	DLD DLST DLTS GCSL KGD4 LAD MRPS36 OGDH PHE3	Homo sapiens (human)
Glycine degradation	2-oxoglutarate dehydrogenase complex component E1 Alpha-ketoglutarate dehydrogenase component 4 Aminomethyltransferase, mitochondrial Dihydrolipoyl dehydrogenase, mitochondrial Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial Glycine cleavage system H protein, mitochondrial Glycine dehydrogenase (decarboxylating), mitochondrial	P09622 P23378 P23434 P36957 P48728 P82909 Q02218	AMT DLD DLST DLTS GCSH GCSL GCSP GCST GLDC KGD4 LAD MRPS36 OGDH PHE3	Homo sapiens (human)
Mitochondrial protein degradation	2-oxoglutarate dehydrogenase complex component E1 3-hydroxyacyl-CoA dehydrogenase type-2 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial 5-aminolevulinate synthase, non-specific, mitochondrial 60 kDa heat shock protein, mitochondrial ADP/ATP translocase 2 ADP/ATP translocase 3 ATP synthase subunit O, mitochondrial ATP synthase subunit a ATP synthase subunit alpha, mitochondrial ATP synthase subunit beta, mitochondrial ATP synthase subunit d, mitochondrial ATP synthase subunit g, mitochondrial ATP synthase subunit gamma, mitochondrial ATP synthase-coupling factor 6, mitochondrial ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial ATP-dependent Clp protease proteolytic subunit, mitochondrial ATP-dependent zinc metalloprotease YME1L1 Acetyl-CoA acetyltransferase, mitochondrial Aconitate hydratase, mitochondrial Acyl-coenzyme A thioesterase 2, mitochondrial Aldehyde dehydrogenase X, mitochondrial Aldehyde dehydrogenase, mitochondrial Arginase-2, mitochondrial Calcium uptake protein 2, mitochondrial Citrate synthase, mitochondrial Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 Cytochrome b-c1 complex subunit 2, mitochondrial Cytochrome b-c1 complex subunit 8 Cytochrome c oxidase subunit 1 Cytochrome c oxidase subunit 2 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial Cytochrome c oxidase subunit 5A, mitochondrial Cytochrome c oxidase subunit 5B, mitochondrial D-beta-hydroxybutyrate dehydrogenase, mitochondrial Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial Delta-1-pyrroline-5-carboxylate synthase Dihydrolipoyl dehydrogenase, mitochondrial Dynamin-like GTPase OPA1, mitochondrial Enoyl-CoA delta isomerase 1, mitochondrial Essential MCU regulator, mitochondrial Ferrochelatase, mitochondrial Fumarate hydratase, mitochondrial Glutamate dehydrogenase 1, mitochondrial Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial Hydroxymethylglutaryl-CoA synthase, mitochondrial Isobutyryl-CoA dehydrogenase, mitochondrial Isocitrate dehydrogenase [NADP], mitochondrial Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial Isoleucine--tRNA ligase, mitochondrial Large ribosomal subunit protein bL12m Large ribosomal subunit protein bL32m Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial Lon protease homolog, mitochondrial Malate dehydrogenase, mitochondrial Metalloendopeptidase OMA1, mitochondrial Mitochondrial import inner membrane translocase subunit Tim10 Mitochondrial import inner membrane translocase subunit Tim17-A Mitochondrial import inner membrane translocase subunit Tim22 Mitochondrial import inner membrane translocase subunit Tim9 Mitochondrial inner membrane m-AAA protease component AFG3L2 Mitochondrial inner membrane m-AAA protease component paraplegin Mitochondrial-processing peptidase subunit alpha NAD kinase 2, mitochondrial NAD-dependent malic enzyme, mitochondrial NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NADH-ubiquinone oxidoreductase chain 1 NADH-ubiquinone oxidoreductase chain 2 NADH-ubiquinone oxidoreductase chain 5 NADH-ubiquinone oxidoreductase chain 6 PRELI domain-containing protein 1, mitochondrial Probable D-lactate dehydrogenase, mitochondrial Propionyl-CoA carboxylase beta chain, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial Pyruvate dehydrogenase E1 component subunit beta, mitochondrial Serine hydroxymethyltransferase, mitochondrial Serine protease HTRA2, mitochondrial Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial Single-stranded DNA-binding protein, mitochondrial Small ribosomal subunit protein uS10m Small ribosomal subunit protein uS2m StAR-related lipid transfer protein 7, mitochondrial Steroidogenic acute regulatory protein, mitochondrial Stress-70 protein, mitochondrial Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial Succinyl-CoA TP53-regulated inhibitor of apoptosis 1 Transcription factor A, mitochondrial Twinkle mtDNA helicase [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial cAMP-dependent protein kinase catalytic subunit alpha	O14949 O43464 O43678 O43715 O60313 O75390 O75489 O75947 O75964 O76031 O95139 P00367 P00395 P00403 P00846 P03886 P03891 P03915 P03923 P05091 P05141 P05166 P06576 P07954 P08559 P09622 P10606 P10809 P11177 P11182 P12236 P13073 P13196 P17612 P18859 P20674 P22695 P22830 P23368 P24752 P25705 P28331 P30837 P34897 P36542 P36776 P38646 P40926 P42126 P45954 P48047 P48735 P49675 P49753 P49821 P50213 P52815 P54868 P54886 P55809 P56181 P62072 P78540 P82664 Q00059 Q02218 Q02338 Q04837 Q10713 Q13011 Q15118 Q16740 Q16836 Q4G0N4 Q86WU2 Q8IYU8 Q96E52 Q96I99 Q96RR1 Q96TA2 Q99595 Q99714 Q99798 Q9BYC8 Q9H4I9 Q9NQZ5 Q9NSE4 Q9NWU1 Q9P0J0 Q9UKU7 Q9UQ90 Q9Y255 Q9Y399 Q9Y4W6 Q9Y584 Q9Y5J7 Q9Y6H1	15E1.1 AAC2 AAC3 ACAD8 ACADSB ACAT ACAT1 ACO2 ACOT2 AFG3L2 ALAS1 ALAS3 ALASH ALDH18A1 ALDH1B1 ALDH2 ALDH5 ALDHX ALDM ANT2 ANT3 ARC42 ARG2 ATP5A ATP5A1 ATP5AL2 ATP5B ATP5C ATP5C1 ATP5CL1 ATP5F1A ATP5F1B ATP5F1C ATP5H ATP5J ATP5L ATP5MG ATP5O ATP5PD ATP5PF ATP5PO ATP6 ATPASE6 ATPM ATPMB ATPO ATPSB BCATE2 BCKDHE2 BDH BDH1 C10orf2 C22orf32 C5orf33 C7orf17 CAR CHCHD2 CLPP CLPX CMAR COI COII COX2 COX4 COX4I1 COX5A COX5B COXI COXII CS DBT DCI DLD ECH1 ECI1 EFHA1 EMRE ERAB FECH FH FTSH1 GCSL GLUD GLUD1 GRIM19 GRP75 GSAS GTT1 HAD HAD1 HADH HADH2 HADHSC HMGCS2 HSD17B10 HSP60 HSPA9 HSPA9B HSPD1 HTRA2 IARS2 IBD IDH2 IDH3A INPP5E KIAA0123 KIAA0567 LAD LDHD LONP1 MAT MDH2 ME2 MICU2 MIMT17 MNADK MPPA MPRP1 MRPL12 MRPL32 MRPL7 MRPP2 MRPS10 MRPS2 MT-ATP6 MT-CO1 MT-CO2 MT-ND1 MT-ND2 MT-ND5 MT-ND6 MTATP6 MTCO1 MTCO2 MTND1 MTND2 MTND5 MTND6 NADH1 NADH2 NADH5 NADH6 NADK2 NADKD1 ND1 ND2 ND5 ND6 NDUFA13 NDUFA2 NDUFB6 NDUFS1 NDUFS3 NDUFV1 NDUFV3 OGDH OMA1 OMI OPA1 OXCT OXCT1 OXSM P5CS PCCB PDHA1 PDHB PDHK1 PDK1 PEO1 PGN PHE1A PHE1B PHE3 PKACA PMPCA PRELI PRELID1 PRKACA PRSS15 PRSS25 PTE2 PTE2A PYCS RPML12 SCHAD SCOT SDR5C1 SDR9C1 SHMT2 SLC25A5 SLC25A6 SMDT1 SPG7 SSBP SSBP1 STAR STARD1 STARD7 SUCLG2 TCF6 TCF6L2 TEX4 TFAM TIM10 TIM17 TIM17A TIM22 TIM9 TIM9A TIMM10 TIMM17 TIMM17A TIMM22 TIMM9 TIMM9A TRIAP1 TWNK UQCRC2 UQCRQ UQOR1 XH98G2 YME1L YME1L1 mt-HSP70	Homo sapiens (human)
Protein hydroxylation	2-oxoglutarate and iron-dependent oxygenase JMJD4 Aspartyl/asparaginyl beta-hydroxylase Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 Bifunctional peptidase and arginyl-hydroxylase JMJD5 Coagulation factor IX Developmentally-regulated GTP-binding protein 1 Developmentally-regulated GTP-binding protein 2 Eukaryotic peptide chain release factor subunit 1 Large ribosomal subunit protein uL15 Large ribosomal subunit protein uL2 Prolyl 3-hydroxylase OGFOD1 RCC1 domain-containing protein 1 RWD domain-containing protein 1 Ribosomal oxygenase 1 Ribosomal oxygenase 2 Small ribosomal subunit protein eS6 Small ribosomal subunit protein uS12 Splicing factor U2AF 65 kDa subunit Zinc finger CCCH domain-containing protein 15	A6NED2 P00740 P0C870 P26368 P46776 P55039 P62266 P62495 P62753 P62917 Q12797 Q6NYC1 Q8IUF8 Q8N371 Q8N543 Q8WU90 Q9H446 Q9H6W3 Q9H9V9 Q9Y295	ASPH BAH C14orf169 DFRP1 DFRP2 DRG1 DRG2 ERF1 ETF1 F9 JMJD4 JMJD5 JMJD6 JMJD7 KDM8 KIAA0585 KIAA1612 LEREPO4 MAPJD MDIG MINA MINA53 NEDD3 NO52 NO66 OGFOD1 PSR PTDSR RCCD1 RF1 RIOX1 RIOX2 RPL27A RPL8 RPS23 RPS6 RWDD1 SUP45L1 TPA1 U2AF2 U2AF65 ZC3H15	Homo sapiens (human)
Lysine catabolism	2-oxoadipate dehydrogenase complex component E1 5-phosphohydroxy-L-lysine phospho-lyase Alpha-aminoadipic semialdehyde dehydrogenase Alpha-aminoadipic semialdehyde synthase, mitochondrial Dihydrolipoyl dehydrogenase, mitochondrial Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial Glutaryl-CoA dehydrogenase, mitochondrial Hydroxylysine kinase Ketimine reductase mu-crystallin Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Mitochondrial 2-oxodicarboxylate carrier Peroxisomal sarcosine oxidase	A2RU49 P09622 P36957 P49419 Q14894 Q8IUZ5 Q8N5Z0 Q92947 Q96HY7 Q9BQT8 Q9P0Z9 Q9UDR5	AADAT AASS AGPHD1 AGXT2L2 ALDH7A1 ATQ1 CRYM DHTKD1 DLD DLST DLTS GCDH GCSL HYKK KAT2 KIAA1630 KYAT2 LAD LPIPOX ODC PHE3 PHYKPL PIPOX PSO SLC25A21 THBP	Homo sapiens (human)
Ubiquinol biosynthesis	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial 4-hydroxybenzoate polyprenyltransferase, mitochondrial 5-demethoxyubiquinone hydroxylase, mitochondrial All trans-polyprenyl-diphosphate synthase PDSS1 All trans-polyprenyl-diphosphate synthase PDSS2 Atypical kinase COQ8A, mitochondrial Atypical kinase COQ8B, mitochondrial Ubiquinone biosynthesis O-methyltransferase, mitochondrial Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial Ubiquinone biosynthesis protein COQ9, mitochondrial	O75208 Q5HYK3 Q5T2R2 Q86YH6 Q8NI60 Q96D53 Q96H96 Q99807 Q9NZJ6 Q9Y2Z9 Q9Y3A0	ADCK3 ADCK4 C16orf49 C6orf210 CABC1 CL640 COQ2 COQ3 COQ4 COQ5 COQ6 COQ7 COQ8A COQ8B COQ9 DLP1 DPS1 PDSS1 PDSS2 TPRT	Homo sapiens (human)
Glycosphingolipid biosynthesis	2-hydroxyacylsphingosine 1-beta-galactosyltransferase Alpha-2,8-sialyltransferase 8E Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 Beta-1,3-galactosyltransferase 4 Beta-1,4 N-acetylgalactosaminyltransferase 1 Beta-1,4-galactosyltransferase 5 Beta-1,4-galactosyltransferase 6 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 Ceramide glucosyltransferase Ceramide kinase Galactoside alpha-(1,2)-fucosyltransferase 1 Galactoside alpha-(1,2)-fucosyltransferase 2 Galactosylceramide sulfotransferase Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase Lactosylceramide 4-alpha-galactosyltransferase Lactosylceramide alpha-2,3-sialyltransferase UDP-GalNAc	O15466 O43286 O75752 O96024 P19526 Q00973 Q10981 Q11203 Q16739 Q16842 Q16880 Q8TCT0 Q969X2 Q99999 Q9BVH7 Q9BYG0 Q9NPC4 Q9UBX8 Q9UNP4	A14GALT A4GALT A4GALT1 B3GALNT1 B3GALT3 B3GALT4 B3GNT5 B4GALNT1 B4GALT5 B4GALT6 CERK CGT CST FUT1 FUT2 GAL3ST1 GALGT GALT4 H HSC KIAA1646 SEC2 SIAT2 SIAT4B SIAT6 SIAT7E SIAT7F SIAT8E SIAT9 ST3GAL2 ST3GAL3 ST3GAL5 ST6GALNAC5 ST6GALNAC6 ST8SIA5 UGCG UGT4 UGT8	Homo sapiens (human)
Alpha-oxidation of phytanate	2-hydroxyacyl-CoA lyase 1 Long-chain fatty acid transport protein 2 Peroxisomal membrane protein PMP34 Peroxisomal trans-2-enoyl-CoA reductase Phytanoyl-CoA dioxygenase, peroxisomal	O14832 O14975 O43808 Q9BY49 Q9UJ83	ACSVL1 FACVL1 FATP2 HACL1 HPCL HPCL2 PAHX PECR PHYH PHYH2 PMP34 SDR29C1 SLC25A17 SLC27A2 VLACS	Homo sapiens (human)
RA biosynthesis pathway	2-aminomuconic semialdehyde dehydrogenase Alcohol dehydrogenase 1A Alcohol dehydrogenase 1C Aldehyde dehydrogenase 1A1 Aldo-keto reductase family 1 member C3 All-trans-retinol dehydrogenase [NAD(+)] ADH4 Cellular retinoic acid-binding protein 1 Cytochrome P450 26A1 Cytochrome P450 26B1 Cytochrome P450 26C1 Dehydrogenase/reductase SDR family member 4 Dehydrogenase/reductase SDR family member 9 Epidermal retinol dehydrogenase 2 Retinal dehydrogenase 2 Retinaldehyde dehydrogenase 3 Retinol dehydrogenase 10 Retinol dehydrogenase 11 Retinol dehydrogenase 13 Retinol dehydrogenase 14 Retinol dehydrogenase 16 Retinol dehydrogenase 5 Short-chain dehydrogenase/reductase 3	O43174 O75452 O75911 O94788 P00326 P00352 P07327 P08319 P29762 P42330 P47895 Q6V0L0 Q8IZV5 Q8N3Y7 Q8NBN7 Q8TC12 Q92781 Q9BPW9 Q9BTZ2 Q9H2A2 Q9HBH5 Q9NR63	ADH1 ADH1A ADH1C ADH2 ADH3 ADH4 AKR1C3 ALDC ALDH1 ALDH12 ALDH1A1 ALDH1A2 ALDH1A3 ALDH6 ALDH8A1 ARSDR1 CRABP1 CYP26 CYP26A1 CYP26A2 CYP26B1 CYP26C1 DDH1 DHRS3 DHRS4 DHRS9 HSD17B5 HSD17B9 KIAA0119 P450RAI1 P450RAI2 PAN2 PGFS PSDR1 PUMB1 RALDH2 RBP5 RDH1 RDH10 RDH11 RDH13 RDH14 RDH15 RDH16 RDH17 RDH5 RDHE2 RODH4 SDR16C1 SDR16C4 SDR16C5 SDR25C2 SDR7C1 SDR7C3 SDR7C4 SDR9C4 SDR9C5 SDR9C8	Homo sapiens (human)
Degradation of cysteine and homocysteine	2-aminoethanethiol dioxygenase 3-mercaptopyruvate sulfurtransferase Acidic amino acid decarboxylase GADL1 Aspartate aminotransferase, mitochondrial Cystathionine gamma-lyase Cysteine dioxygenase type 1 Cysteine sulfinic acid decarboxylase Flavin-containing monooxygenase 1 Thioredoxin, mitochondrial Thiosulfate sulfurtransferase	P00505 P25325 P32929 Q01740 Q16762 Q16878 Q6ZQY3 Q96SZ5 Q99757 Q9Y600	ADO C10orf22 CDO1 CSAD CSD CTH FMO1 GADL1 GOT2 KYAT4 MPST TRX2 TST TST2 TXN2	Homo sapiens (human)
Tryptophan catabolism	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase 3-hydroxyanthranilate 3,4-dioxygenase Amino acid transporter heavy chain SLC3A2 Indoleamine 2,3-dioxygenase 1 Indoleamine 2,3-dioxygenase 2 Kynureninase Kynurenine 3-monooxygenase Kynurenine formamidase Kynurenine--oxoglutarate transaminase 1 Kynurenine--oxoglutarate transaminase 3 Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Large neutral amino acids transporter small subunit 1 Neutral amino acid uniporter 4 Tryptophan 2,3-dioxygenase	O15229 P08195 P14902 P46952 P48775 Q01650 Q16719 Q16773 Q63HM1 Q6YBV0 Q6YP21 Q6ZQW0 Q8N5Z0 Q8TDX5	AADAT ACMSD AFMID CCBL1 CCBL2 CD98LC HAAO IDO IDO1 IDO2 INDO INDOL1 KAT2 KAT3 KMO KYAT1 KYAT2 KYAT3 KYNU LAT1 MDU1 MPE16 PAT4 SLC36A4 SLC3A2 SLC7A5 TDO TDO2	Homo sapiens (human)
Triglyceride biosynthesis	2-acylglycerol O-acyltransferase 1 2-acylglycerol O-acyltransferase 2 2-acylglycerol O-acyltransferase 3 Alkylglycerol monooxygenase Diacylglycerol O-acyltransferase 1 Diacylglycerol O-acyltransferase 2 Glycerol kinase 2 Glycerol kinase 3 Glycerol kinase Glycerol-3-phosphate acyltransferase 1, mitochondrial Glycerol-3-phosphate acyltransferase 2, mitochondrial Phosphatidate phosphatase LPIN1 Phosphatidate phosphatase LPIN2 Phosphatidate phosphatase LPIN3	O75907 P32189 Q14409 Q14410 Q14693 Q3SYC2 Q6NUI2 Q6ZNB7 Q86VF5 Q92539 Q96PD6 Q96PD7 Q9BQK8 Q9HCL2	AGMO AGRP1 DC2 DC5 DC7 DGAT DGAT1 DGAT2 DGAT2L1 DGAT2L5 DGAT2L7 GK GK2 GK3 GK3P GKP2 GKP3 GKTA GKTB GPAM GPAT1 GPAT2 KIAA0188 KIAA0249 KIAA1560 LIPN3L LPIN1 LPIN2 LPIN3 MOGAT1 MOGAT2 MOGAT3 TMEM195	Homo sapiens (human)
Peroxisomal lipid metabolism	2-Hydroxyacid oxidase 2 Acyl-CoA-binding domain-containing protein 4 Acyl-CoA-binding domain-containing protein 5 Acyl-coenzyme A diphosphatase NUDT19 Peroxisomal coenzyme A diphosphatase NUDT7	A8MXV4 P0C024 Q5T8D3 Q8NC06 Q9NYQ3	ACBD4 ACBD5 HAO2 HAOX2 KIAA1996 NUDT19 NUDT7	Homo sapiens (human)
Glyoxylate metabolism and glycine degradation	2-Hydroxyacid oxidase 1 4-hydroxy-2-oxoglutarate aldolase, mitochondrial Alanine--glyoxylate aminotransferase 2, mitochondrial Alanine--glyoxylate aminotransferase Aspartate aminotransferase, mitochondrial D-amino-acid oxidase D-aspartate oxidase Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial Glycine N-methyltransferase Glyoxylate reductase/hydroxypyruvate reductase Hydroxyproline dehydrogenase Peroxisomal membrane protein 2	P00505 P14920 P21549 P30038 Q14749 Q86XE5 Q99489 Q9BYV1 Q9NR77 Q9UBQ7 Q9UF12 Q9UJM8	AGT1 AGT2 AGXT AGXT2 ALDH4 ALDH4A1 C10orf65 DAMOX DAO DDO DHDPSL GLXR GNMT GOT2 GOX1 GRHPR HAO1 HOGA1 HSPOX1 HYPDH KYAT4 P5CDH PMP22 PRODH2 PXMP2 SPAT	Homo sapiens (human)
Peroxisomal protein import	2-Hydroxyacid oxidase 1 2-Hydroxyacid oxidase 2 2-hydroxyacyl-CoA lyase 1 3-ketoacyl-CoA thiolase, peroxisomal AN1-type zinc finger protein 6 Acyl-coenzyme A diphosphatase NUDT19 Acyl-coenzyme A thioesterase 2, mitochondrial Acyl-coenzyme A thioesterase 8 Alanine--glyoxylate aminotransferase Alkyldihydroxyacetonephosphate synthase, peroxisomal Alpha-methylacyl-CoA racemase Bifunctional epoxide hydrolase 2 Bile acid-CoA Carnitine O-acetyltransferase Catalase D-amino-acid oxidase D-aspartate oxidase Dehydrogenase/reductase SDR family member 4 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial Dihydroxyacetone phosphate acyltransferase Glutathione S-transferase kappa 1 Hydroxymethylglutaryl-CoA lyase, mitochondrial Insulin-degrading enzyme Isocitrate dehydrogenase [NADP] cytoplasmic Lon protease homolog 2, peroxisomal Long-chain fatty acid transport protein 2 Nitric oxide synthase, inducible Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] Peroxisomal ATPase PEX1 Peroxisomal ATPase PEX6 Peroxisomal N(1)-acetyl-spermine/spermidine oxidase Peroxisomal acyl-coenzyme A oxidase 1 Peroxisomal acyl-coenzyme A oxidase 2 Peroxisomal acyl-coenzyme A oxidase 3 Peroxisomal bifunctional enzyme Peroxisomal carnitine O-octanoyltransferase Peroxisomal coenzyme A diphosphatase NUDT7 Peroxisomal leader peptide-processing protease Peroxisomal membrane protein PEX13 Peroxisomal membrane protein PEX14 Peroxisomal multifunctional enzyme type 2 Peroxisomal sarcosine oxidase Peroxisomal succinyl-coenzyme A thioesterase Peroxisomal targeting signal 2 receptor Peroxisomal trans-2-enoyl-CoA reductase Peroxisome assembly protein 12 Peroxisome assembly protein 26 Peroxisome biogenesis factor 10 Peroxisome biogenesis factor 2 Phytanoyl-CoA dioxygenase, peroxisomal Polyubiquitin-B Polyubiquitin-C Protein Mpv17 Sterol carrier protein 2 Ubiquitin carboxyl-terminal hydrolase 9X Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A8MXV4 O00116 O00623 O00628 O14734 O14832 O14975 O15228 O15254 O43933 O60683 O75381 O75874 P04040 P09110 P0C024 P0CG47 P0CG48 P14735 P14920 P21549 P22307 P28328 P34913 P35228 P35914 P39210 P43155 P49753 P51659 P51668 P61077 P62837 P62979 P62987 Q08426 Q13011 Q13608 Q14032 Q15067 Q2T9J0 Q6FIF0 Q6QHF9 Q7Z412 Q86WA8 Q8N9L9 Q92968 Q93008 Q99424 Q99489 Q9BTZ2 Q9BY49 Q9NUI1 Q9NYQ3 Q9P0Z9 Q9UHK6 Q9UJ83 Q9UJM8 Q9UKG9 Q9Y2Q3	ACAA ACAA1 ACOT2 ACOT4 ACOT8 ACOX ACOX1 ACOX2 ACOX3 ACSVL1 ACTEIII AGPS AGT1 AGXT AMACR AWP1 BAAT BRCOX CAT CAT1 COT CRAT CROT DAMOX DAO DAPAT DDO DECR2 DFFRX DHAPAT DHRS4 ECH1 ECHD EDH17B4 EHHADH EPHX2 FACVL1 FAM FATP2 GNPAT GOX1 GSTK1 HACL1 HAO1 HAO2 HAOX2 HMGCL HPCL HPCL2 HSD17B4 IDE IDH1 LONP LONP2 LPIPOX MPV17 NOS2 NOS2A NUDT19 NUDT7 PAF1 PAF3 PAHX PAO PAOX PDCR PECR PEX1 PEX10 PEX12 PEX13 PEX14 PEX2 PEX26 PEX6 PEX7 PHYH PHYH2 PICD PIPOX PMP3 PMP35 PRCOX PSO PTE1 PTE2 PTE2A PTE2B PTEIB PTHIO PTS2R PUBC1 PXAAA1 PXMP3 RNF69 RNF72 RPS27A SCP2 SDR17C1 SDR25C2 SDR29C1 SDR8C1 SFT SLC27A2 SPAT TYSND1 UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBC5C UBCEP1 UBCEP2 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBE2D1 UBE2D2 UBE2D3 USP9 USP9X VLACS ZA20D3 ZFAND6	Homo sapiens (human)

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