GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **1851 - 1875** of **2090** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol
TNFs bind their physiological receptors	CD27 antigen CD70 antigen Ectodysplasin-A receptor-associated adapter protein Ectodysplasin-A Lymphotoxin-alpha Tumor necrosis factor ligand superfamily member 11 Tumor necrosis factor ligand superfamily member 13 Tumor necrosis factor ligand superfamily member 13B Tumor necrosis factor ligand superfamily member 14 Tumor necrosis factor ligand superfamily member 15 Tumor necrosis factor ligand superfamily member 18 Tumor necrosis factor ligand superfamily member 4 Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor ligand superfamily member 8 Tumor necrosis factor ligand superfamily member 9 Tumor necrosis factor receptor superfamily member 11B Tumor necrosis factor receptor superfamily member 13B Tumor necrosis factor receptor superfamily member 14 Tumor necrosis factor receptor superfamily member 17 Tumor necrosis factor receptor superfamily member 18 Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor superfamily member 1B Tumor necrosis factor receptor superfamily member 25 Tumor necrosis factor receptor superfamily member 27 Tumor necrosis factor receptor superfamily member 4 Tumor necrosis factor receptor superfamily member 6B Tumor necrosis factor receptor superfamily member 8 Tumor necrosis factor receptor superfamily member 9 Tumor necrosis factor receptor superfamily member EDAR	O00300 O14788 O14836 O43557 O75888 O95150 O95407 P01374 P19438 P20333 P23510 P26842 P28908 P32970 P32971 P41273 P43489 Q02223 Q07011 Q53ZZ1 Q8WWZ3 Q92838 Q92956 Q93038 Q9HAV5 Q9UNE0 Q9UNG2 Q9Y275 Q9Y5U5	AITR AITRL APO3 APRIL BAFF BCM BCMA BLYS CD137 CD27 CD27L CD27LG CD30 CD30L CD30LG CD70 D1S166E DCR3 DDR3 DL DR3 ED1 EDA EDA2 EDA2R EDAR EDARADD FASLG GITR GITRL HVEA HVEM HVEML ILA LIGHT LTA OCIF OPG OPGL RANKL TACI TALL1 TALL2 TL1 TL6 TNFAR TNFB TNFBR TNFR1 TNFR2 TNFRSF11B TNFRSF12 TNFRSF13B TNFRSF14 TNFRSF17 TNFRSF18 TNFRSF1A TNFRSF1B TNFRSF25 TNFRSF27 TNFRSF4 TNFRSF6B TNFRSF7 TNFRSF8 TNFRSF9 TNFSF1 TNFSF11 TNFSF13 TNFSF13B TNFSF14 TNFSF15 TNFSF18 TNFSF20 TNFSF4 TNFSF6 TNFSF7 TNFSF8 TNFSF9 TNLG1A TR6 TRANCE TXGP1 TXGP1L VEGI WSL WSL1 XEDAR ZTNF2 ZTNF4
TP53 Regulates Metabolic Genes	14-3-3 protein beta/alpha 14-3-3 protein epsilon 14-3-3 protein eta 14-3-3 protein gamma 14-3-3 protein sigma 14-3-3 protein theta 14-3-3 protein zeta/delta 5'-AMP-activated protein kinase catalytic subunit alpha-1 5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-1 5'-AMP-activated protein kinase subunit gamma-2 5'-AMP-activated protein kinase subunit gamma-3 Cellular tumor antigen p53 Cytochrome c oxidase assembly protein COX11, mitochondrial Cytochrome c oxidase assembly protein COX14 Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial Cytochrome c oxidase assembly protein COX18, mitochondrial Cytochrome c oxidase assembly protein COX19 Cytochrome c oxidase assembly protein COX20, mitochondrial Cytochrome c oxidase subunit 1 Cytochrome c oxidase subunit 2 Cytochrome c oxidase subunit 3 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial Cytochrome c oxidase subunit 5A, mitochondrial Cytochrome c oxidase subunit 5B, mitochondrial Cytochrome c oxidase subunit 6A1, mitochondrial Cytochrome c oxidase subunit 6B1 Cytochrome c oxidase subunit 6C Cytochrome c oxidase subunit 7A-related protein, mitochondrial Cytochrome c oxidase subunit 7B, mitochondrial Cytochrome c oxidase subunit 7C, mitochondrial Cytochrome c oxidase subunit 8A, mitochondrial Cytochrome c oxidase subunit NDUFA4 Cytochrome c DNA damage-inducible transcript 4 protein Fructose-2,6-bisphosphatase TIGAR GTP-binding protein Rheb Glucose-6-phosphate 1-dehydrogenase Glucose-6-phosphate isomerase Glutaminase kidney isoform, mitochondrial Glutaminase liver isoform, mitochondrial Glutathione peroxidase 2 Hamartin Helicase MOV-10 Leucine-rich PPR motif-containing protein, mitochondrial Neutral amino acid transporter 9 Peroxiredoxin-1 Peroxiredoxin-2 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Protein SCO1 homolog, mitochondrial Protein SCO2 homolog, mitochondrial Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein A Ras-related GTP-binding protein B Ras-related GTP-binding protein C Ras-related GTP-binding protein D Regulatory-associated protein of mTOR Ribonucleoside-diphosphate reductase subunit M2 B Serine/threonine-protein kinase mTOR Sestrin-2 Sestrin-3 Surfeit locus protein 1 Target of rapamycin complex subunit LST8 Thioredoxin reductase 1, cytoplasmic Thioredoxin Translational activator of cytochrome c oxidase 1 Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein Tuberin Tumor protein 63	O00483 O14548 O43504 O43741 O43819 O75880 O94925 P00395 P00403 P00414 P04637 P06744 P09669 P10176 P10599 P10606 P11413 P12074 P13073 P14854 P15954 P18283 P20674 P24311 P27348 P31749 P31751 P31946 P31947 P32119 P42345 P42704 P49815 P54619 P54646 P58004 P58005 P60484 P61981 P62258 P63104 P99999 Q04917 Q06830 Q0VGL1 Q13131 Q15382 Q15526 Q16881 Q49B96 Q5RI15 Q5VZM2 Q6IAA8 Q7L523 Q7LG56 Q8N122 Q8N8Q8 Q8NBW4 Q8NDV7 Q92574 Q96I36 Q9BSH4 Q9BVC4 Q9H3D4 Q9H9G7 Q9HB90 Q9HCE1 Q9HCJ0 Q9HCK5 Q9NQ88 Q9NQL2 Q9NX09 Q9P0S2 Q9UGI9 Q9UGJ0 Q9UHA4 Q9UI32 Q9UKV8 Q9UL18 Q9UPQ9 Q9Y243 Q9Y2Q5 Q9Y478 Q9Y6N1	AGO1 AGO2 AGO3 AGO4 AKT1 AKT2 AKT3 AMPK AMPK1 AMPK2 AMPKG3 C11orf59 C12orf5 C12orf62 C14orf112 C7orf59 CAGH26 CCDC44 COI COII COIII COX11 COX14 COX16 COX18 COX19 COX2 COX20 COX4 COX4I1 COX5A COX5B COX6A1 COX6AL COX6B COX6B1 COX6C COX7A2L COX7AR COX7B COX7C COX7RP COX8 COX8A COX8L COXI COXII COXIII CYC CYCS DDIT4 EIF2C1 EIF2C2 EIF2C3 EIF2C4 FAM36A FRAP FRAP1 FRAP2 G6PD GA GBL GLS GLS1 GLS2 GPI GPX2 GRIM12 HBXIP HME1 Hi95 KDRF KET KIAA0243 KIAA0838 KIAA1093 KIAA1303 KIAA1460 KIAA1567 KIAA1582 KIAA1631 LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 LRP130 LRPPRC LST8 MAP2K1IP1 MAPBPIP MAPKSP1 MLST8 MMAC1 MOV10 MT-CO1 MT-CO2 MT-CO3 MTCO1 MTCO2 MTCO3 MTOR NDUFA4 NKEFB OXA1L2 P53 P53R2 P63 P73H P73L PAGA PAGB PDRO PKB PKBG PRDX1 PRDX2 PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 PTEN RAC RAFT1 RAPT1 RAPTOR REDD1 RHEB RHEB2 ROBLD3 RPTOR RRAGA RRAGB RRAGC RRAGD RRM2B RTP801 SCO1 SCO2 SCOD1 SESN2 SESN3 SEST2 SEST3 SFN SLC38A9 SURF-1 SURF1 TACO1 TDPX1 TDPX2 TEP1 TIGAR TNRC6 TNRC6A TNRC6B TNRC6C TP53 TP63 TP73L TRDX TRX TRX1 TSC TSC1 TSC2 TSC4 TXN TXNRD1 URLC11 XIP YWHA1 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ
TP53 Regulates Transcription of Caspase Activators and Caspases	Apoptotic protease-activating factor 1 Caspase-10 Caspase-1 Caspase-2 Caspase-6 Cellular tumor antigen p53 Death domain-containing protein CRADD NLR family CARD domain-containing protein 4 Serine-protein kinase ATM Tumor protein 63 Tumor protein p73 p53-induced death domain-containing protein 1	O14727 O15350 P04637 P29466 P42575 P55212 P78560 Q13315 Q92851 Q9H3D4 Q9HB75 Q9NPP4	APAF1 ATM CARD12 CASP1 CASP10 CASP2 CASP6 CLAN CLAN1 CRADD ICH1 IL1BC IL1BCE IPAF KET KIAA0413 LRDD MCH2 MCH4 NEDD2 NLRC4 P53 P63 P73 P73H P73L PIDD PIDD1 RAIDD TP53 TP63 TP73 TP73L
TP53 Regulates Transcription of DNA Repair Genes	Breast cancer type 1 susceptibility protein CDK-activating kinase assembly factor MAT1 Cellular tumor antigen p53 Cyclic AMP-dependent transcription factor ATF-2 Cyclin-H Cyclin-K Cyclin-T1 Cyclin-T2 Cyclin-dependent kinase 12 Cyclin-dependent kinase 13 Cyclin-dependent kinase 7 Cyclin-dependent kinase 9 DNA damage-binding protein 2 DNA mismatch repair protein Mlh1 DNA mismatch repair protein Msh2 DNA repair protein RAD51 homolog 4 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Elongin-A2 Elongin-A Elongin-B Elongin-C FACT complex subunit SPT16 FACT complex subunit SSRP1 Fanconi anemia group C protein Fanconi anemia group D2 protein Fanconi anemia group I protein General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Mediator of DNA damage checkpoint protein 1 Mismatch repair endonuclease PMS2 Negative elongation factor A Negative elongation factor B Negative elongation factor C/D Negative elongation factor E Protein c-Fos RNA polymerase II elongation factor ELL RNA polymerase II subunit A C-terminal domain phosphatase Serine-protein kinase ATM Serine/threonine-protein kinase ATR Serine/threonine-protein kinase Chk1 Transcription elongation factor A protein 1 Transcription elongation factor SPT4 Transcription elongation factor SPT5 Transcription factor Jun	O00267 O14757 O15514 O60563 O60583 O75771 O75909 P01100 P04637 P05412 P13984 P15336 P18074 P18615 P19387 P19388 P19447 P23193 P24928 P30876 P32780 P35269 P36954 P38398 P40692 P43246 P50613 P50750 P51946 P51948 P52434 P52435 P53803 P54278 P55199 P61218 P62487 P62875 P63272 Q00597 Q08945 Q13315 Q13535 Q13888 Q13889 Q14004 Q14241 Q14676 Q15369 Q15370 Q6ZYL4 Q8IXH7 Q8IYF1 Q8WX92 Q92466 Q92759 Q9BXW9 Q9H3P2 Q9NVI1 Q9NYV4 Q9Y5B0 Q9Y5B9	ATF2 ATM ATR BRCA1 BTF2 BTF2P44 C19orf17 C6orf175 CAK CAK1 CAP35 CCNH CCNK CCNT1 CCNT2 CDC2L CDC2L4 CDC2L5 CDK12 CDK13 CDK7 CDK9 CDKN7 CHED CHEK1 CHK1 COBRA1 COCA2 CPR4 CREB2 CREBP1 CRK7 CRKRS CTDP1 DDB2 ELL ELOA ELOA2 ELOB ELOC ERCC2 ERCC3 FAC FACC FACD FACT140 FACT80 FACTP140 FANCC FANCD2 FANCI FCP1 FOS FRP1 G0S7 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 GTF2S JUN KIAA0170 KIAA0904 KIAA1182 KIAA1791 KIAA1794 MAT1 MDC1 MLH1 MNAT1 MO15 MSH2 NELFA NELFB NELFCD NELFD NELFE NFBD1 P53 PMS2 PMSL2 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAD51D RAD51L3 RAP30 RAP74 RD RDBP RNF53 RNF66 RPB7 SPT4H SPT5 SPT5H SSRP1 STK1 SUPT16H SUPT4H SUPT4H1 SUPT5H TAK TCEA1 TCEB1 TCEB2 TCEB3 TCEB3B TCEB3L TFIIS TH1 TH1L TP53 TTDA WHSC2 XPB XPBC XPD XPDC
TP53 Regulates Transcription of Death Receptors and Ligands	Apoptosis-stimulating of p53 protein 1 Apoptosis-stimulating of p53 protein 2 Cellular tumor antigen p53 Insulin-like growth factor-binding protein 3 receptor Insulin-like growth factor-binding protein 3 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 10C Tumor necrosis factor receptor superfamily member 10D Tumor necrosis factor receptor superfamily member 6 Tumor protein 63 Tumor protein p73	O00220 O14763 O14798 O15350 P04637 P17936 P25445 Q13625 Q86XT9 Q96KQ4 Q9H3D4 Q9UBN6	APO2 APT1 ASPP1 ASPP2 BBP DCR1 DCR2 DR4 DR5 FAS FAS1 IBP3 IGFBP3 KET KIAA0771 KILLER LIT P53 P63 P73 P73H P73L PPP1R13B TMEM219 TNFRSF10A TNFRSF10B TNFRSF10C TNFRSF10D TNFRSF6 TP53 TP53BP2 TP63 TP73 TP73L TRAILR1 TRAILR2 TRAILR3 TRAILR4 TRICK2 TRID TRUNDD ZTNFR9
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	Apoptosis regulator BAX Apoptosis-stimulating of p53 protein 1 Apoptosis-stimulating of p53 protein 2 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like BH3-interacting domain death agonist Bcl-2-binding component 3, isoforms 1/2 CREB-binding protein Cellular tumor antigen p53 Ferroptosis suppressor protein 1 Metalloreductase STEAP3 PRELI domain containing protein 3A PRELI domain-containing protein 1, mitochondrial Phorbol-12-myristate-13-acetate-induced protein 1 Serine-protein kinase ATM TP53-regulated inhibitor of apoptosis 1 Tumor protein 63 Tumor protein p53-inducible nuclear protein 1 Tumor protein p73 Zinc finger protein 420 p53-regulated apoptosis-inducing protein 1	O15350 O43715 O60238 P04637 P55957 Q07812 Q13315 Q13625 Q13794 Q658P3 Q8TAQ5 Q92793 Q96A56 Q96KQ4 Q96N28 Q9BRQ8 Q9BXH1 Q9H3D4 Q9HCN2 Q9Y255	15E1.1 AIFM2 AMID ASPP1 ASPP2 ATM BAX BBC3 BBP BCL2L4 BID BNIP3A BNIP3H BNIP3L C18orf43 CBP CREBBP KET KIAA0771 NIX NOXA P53 P53DINP1 P63 P73 P73H P73L PMAIP1 PPP1R13B PRELI PRELID1 PRELID3A PRG3 PUMA SIP SLMO1 STEAP3 TP53 TP53AIP1 TP53BP2 TP53INP1 TP63 TP73 TP73L TRIAP1 TSAP6 ZNF420
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	AT-rich interactive domain-containing protein 3A Cellular tumor antigen p53 Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B G1/S-specific cyclin-E1 G1/S-specific cyclin-E2 Poly(rC)-binding protein 4 Transcription factor E2F1 Transcription factor E2F7 Transcription factor E2F8 Zinc finger protein 385A	A0AVK6 O96020 P04637 P20248 P24864 P24941 P38936 P46527 P57723 P78396 Q01094 Q96AV8 Q96PM9 Q99856	ARID3A CAP20 CCN1 CCNA CCNA1 CCNA2 CCNE CCNE1 CCNE2 CDK2 CDKN1 CDKN1A CDKN1B CDKN2 CIP1 DRIL1 DRIL3 DRX E2F1 E2F7 E2F8 E2FBP1 HZF KIP1 MDA6 P53 PCBP4 PIC1 RBBP3 RZF SDI1 TP53 WAF1 ZNF385 ZNF385A p27
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	14-3-3 protein sigma Apoptosis regulator BAX Aurora kinase A Cellular tumor antigen p53 Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 Growth arrest and DNA damage-inducible protein GADD45 alpha Histone acetyltransferase p300 Histone-arginine methyltransferase CARM1 M-phase inducer phosphatase 3 Proliferating cell nuclear antigen Protein arginine N-methyltransferase 1 Retinoblastoma-like protein 1 Retinoblastoma-like protein 2 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F4 Zinc finger protein 385A	O14965 P04637 P06493 P12004 P14635 P24522 P28749 P30307 P31947 Q07812 Q08999 Q09472 Q14186 Q14188 Q16254 Q86X55 Q96PM9 Q99873	AIK AIRK1 ARK1 AURA AURKA AYK1 BAX BCL2L4 BTAK CARM1 CCNB CCNB1 CDC2 CDC25C CDC28A CDK1 CDKN1 DDIT1 DP1 DP2 E2F4 EP300 GADD45 GADD45A HME1 HMT2 HRMT1L2 HZF IAK1 IR1B4 P300 P34CDC2 P53 PCNA PRMT1 PRMT4 RB2 RBL1 RBL2 RZF SFN STK15 STK6 TFDP1 TFDP2 TP53 ZNF385 ZNF385A
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	182 kDa tankyrase-1-binding protein CCR4-NOT transcription complex subunit 10 CCR4-NOT transcription complex subunit 11 CCR4-NOT transcription complex subunit 1 CCR4-NOT transcription complex subunit 2 CCR4-NOT transcription complex subunit 3 CCR4-NOT transcription complex subunit 4 CCR4-NOT transcription complex subunit 6-like CCR4-NOT transcription complex subunit 6 CCR4-NOT transcription complex subunit 7 CCR4-NOT transcription complex subunit 8 CCR4-NOT transcription complex subunit 9 Cellular tumor antigen p53 Centromere protein J M-phase inducer phosphatase 3 Nucleophosmin Protein BTG2 Regulator of cell cycle RGCC Serine/threonine-protein kinase PLK2 Serine/threonine-protein kinase PLK3 Zinc finger protein PLAGL1	A5YKK6 O75175 O95628 P04637 P06748 P30307 P78543 Q92600 Q96LI5 Q9C0C2 Q9H4B4 Q9H4X1 Q9H9A5 Q9HC77 Q9NYY3 Q9NZN8 Q9UFF9 Q9UIV1 Q9UKZ1 Q9ULM6 Q9UM63	BTG2 C13orf15 C2orf29 CAF1 CALIF CCR4 CCR4B CCR4a CDC25C CDC36 CDC39 CENPJ CNK CNOT1 CNOT10 CNOT11 CNOT2 CNOT3 CNOT4 CNOT6 CNOT6L CNOT7 CNOT8 CNOT9 CPAP FNK KIAA0691 KIAA1007 KIAA1194 KIAA1741 LAP LENG2 LIP1 LOT1 NOT1 NOT2 NOT3 NOT4 NPM NPM1 P53 PC3 PLAGL1 PLK2 PLK3 POP2 PRK RCD1 RGC32 RGCC RQCD1 SNK TAB182 TNKS1BP1 TP53 ZAC
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	Apoptosis facilitator Bcl-2-like protein 14 Apoptosis-stimulating of p53 protein 1 Apoptosis-stimulating of p53 protein 2 B-cell lymphoma 6 protein Baculoviral IAP repeat-containing protein 5 Cellular tumor antigen p53 Geranylgeranyl transferase type-2 subunit alpha Geranylgeranyl transferase type-2 subunit beta Protein NDRG1 Quinone oxidoreductase PIG3 Rab proteins geranylgeranyltransferase component A 1 Tumor protein 63 Tumor protein p73 p53 apoptosis effector related to PMP-22	O15350 O15392 P04637 P24386 P41182 P53611 Q13625 Q53FA7 Q92597 Q92696 Q96FX8 Q96KQ4 Q9BZR8 Q9H3D4	API4 ASPP1 ASPP2 BBP BCL2L14 BCL5 BCL6 BCLG BIRC5 CAP43 CHM DRG1 GGTB IAP4 KCP1 KET KIAA0771 KRTCAP1 LAZ3 NDRG1 P53 P63 P73 P73H P73L PERP PIG3 PIGPC1 PPP1R13B RABGGTA RABGGTB REP1 RTP TCD THW TP53 TP53BP2 TP53I3 TP63 TP73 TP73L ZBTB27 ZNF51
TRAF3 deficiency - HSE	TIR domain-containing adapter molecule 1 TNF receptor-associated factor 3 Toll-like receptor 3	O15455 Q13114 Q8IUC6	CAP-1 CRAF1 PRVTIRB TICAM1 TLR3 TRAF3 TRAFAMN TRIF
TRAF3-dependent IRF activation pathway	Antiviral innate immune response receptor RIG-I CREB-binding protein E3 ubiquitin-protein ligase RNF135 E3 ubiquitin-protein ligase TRIM4 E3 ubiquitin/ISG15 ligase TRIM25 Histone acetyltransferase p300 Inhibitor of nuclear factor kappa-B kinase subunit epsilon Interferon beta Interferon regulatory factor 3 Interferon regulatory factor 7 Interferon-induced helicase C domain-containing protein 1 Membrane protein Mitochondrial antiviral-signaling protein Non-structural protein 1 Serine/threonine-protein kinase TBK1 Suppressor of IKBKE 1 TNF receptor-associated factor 3	O95786 P01574 P0DOE9 P0DTC5 Q09472 Q13114 Q14164 Q14258 Q14653 Q7Z434 Q8IUD6 Q92793 Q92985 Q9BRV8 Q9BYX4 Q9C037 Q9UHD2	1C CAP-1 CBP CRAF1 CREBBP DDX58 EFP EP300 IFB IFIH1 IFNB IFNB1 IKBKE IKKE IKKI IPS1 IRF3 IRF7 KIAA0151 KIAA1271 M MAVS MDA5 NAK NS1 P300 RH116 RIGI RNF135 RNF147 RNF87 SIKE SIKE1 TBK1 TRAF3 TRAFAMN TRIM25 TRIM4 VISA ZNF147
TRAF6 mediated IRF7 activation	Antiviral innate immune response receptor RIG-I CREB-binding protein E3 ubiquitin-protein ligase RNF135 E3 ubiquitin-protein ligase TRIM4 E3 ubiquitin/ISG15 ligase TRIM25 Histone acetyltransferase p300 Inhibitor of nuclear factor kappa-B kinase subunit epsilon Interferon alpha-1/13 Interferon alpha-10 Interferon alpha-14 Interferon alpha-16 Interferon alpha-17 Interferon alpha-21 Interferon alpha-2 Interferon alpha-4 Interferon alpha-5 Interferon alpha-6 Interferon alpha-7 Interferon alpha-8 Interferon beta Interferon regulatory factor 3 Interferon regulatory factor 7 Interferon-induced helicase C domain-containing protein 1 Mitochondrial antiviral-signaling protein Serine/threonine-protein kinase TBK1 Suppressor of IKBKE 1 TNF receptor-associated factor 2 TNF receptor-associated factor 6 TRAF family member-associated NF-kappa-B activator	O95786 P01562 P01563 P01566 P01567 P01568 P01569 P01570 P01571 P01574 P05013 P05014 P05015 P32881 Q09472 Q12933 Q14164 Q14258 Q14653 Q7Z434 Q8IUD6 Q92793 Q92844 Q92985 Q9BRV8 Q9BYX4 Q9C037 Q9UHD2 Q9Y4K3	CBP CREBBP DDX58 EFP EP300 IFB IFIH1 IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA2A IFNA2B IFNA2C IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNB IFNB1 IKBKE IKKE IKKI IPS1 IRF3 IRF7 ITRAF KIAA0151 KIAA1271 MAVS MDA5 NAK P300 RH116 RIGI RNF135 RNF147 RNF85 RNF87 SIKE SIKE1 TANK TBK1 TRAF2 TRAF6 TRAP3 TRIM25 TRIM4 VISA ZNF147
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling	Interferon regulatory factor 7 Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase 4 Myeloid differentiation primary response protein MyD88 TNF receptor-associated factor 6 Toll-like receptor 7 Toll-like receptor 9 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1	P51617 P61088 Q13404 Q92985 Q99836 Q9NR96 Q9NWZ3 Q9NYK1 Q9Y4K3	BLU CROC1 IRAK IRAK1 IRAK4 IRF7 MYD88 RNF85 TLR7 TLR9 TRAF6 UBE2N UBE2V UBE2V1 UEV1
TRAF6 mediated NF-kB activation	Advanced glycosylation end product-specific receptor Amyloid-beta precursor protein Antiviral innate immune response receptor RIG-I E3 ubiquitin-protein ligase RNF135 E3 ubiquitin-protein ligase TRIM4 E3 ubiquitin/ISG15 ligase TRIM25 High mobility group protein B1 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interferon-induced helicase C domain-containing protein 1 Mitochondrial antiviral-signaling protein Mitogen-activated protein kinase kinase kinase 1 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha NF-kappa-B inhibitor beta NF-kappa-B inhibitor-interacting Ras-like protein 1 NF-kappa-B inhibitor-interacting Ras-like protein 2 Nuclear factor NF-kappa-B p100 subunit Nuclear factor NF-kappa-B p105 subunit Protein S100-A12 Protein S100-B Serum amyloid A-1 protein TNF receptor-associated factor 2 TNF receptor-associated factor 6 Transcription factor p65	O14920 O15111 O95786 P04271 P05067 P09429 P0DJI8 P19838 P25963 P80511 Q00653 Q04206 Q12933 Q13233 Q14258 Q15109 Q15653 Q7Z434 Q8IUD6 Q9BYX4 Q9C037 Q9NYR9 Q9NYS0 Q9Y4K3 Q9Y6K9	A4 AD1 AGER APP CHUK DDX58 EFP FIP3 HMG1 HMGB1 IFIH1 IKBA IKBB IKBKB IKBKG IKKA IKKB IPS1 KBRAS1 KBRAS2 KIAA1271 LYT10 MAD3 MAP3K1 MAPKKK1 MAVS MDA5 MEKK MEKK1 NEMO NFKB1 NFKB2 NFKB3 NFKBI NFKBIA NFKBIB NKIRAS1 NKIRAS2 RAGE RELA RH116 RIGI RNF135 RNF147 RNF85 RNF87 S100A12 S100B SAA1 TCF16 TRAF2 TRAF6 TRAP3 TRIM25 TRIM4 TRIP9 VISA ZNF147
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-associated kinase-like 2 Mitogen-activated protein kinase kinase kinase 1 Myeloid differentiation primary response protein MyD88 TNF receptor-associated factor 6 Toll-like receptor 7 Toll-like receptor 9	O43187 P51617 Q13233 Q99836 Q9BQ95 Q9NR96 Q9NWZ3 Q9NYK1 Q9Y4K3	ECSIT IRAK IRAK1 IRAK2 IRAK4 MAP3K1 MAPKKK1 MEKK MEKK1 MYD88 RNF85 TLR7 TLR9 TRAF6
TRAF6-mediated induction of TAK1 complex within TLR4 complex	Interleukin-1 receptor-associated kinase-like 2 Lymphocyte antigen 96 Mitogen-activated protein kinase kinase kinase 7 Monocyte differentiation antigen CD14 Polyubiquitin-B Polyubiquitin-C TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 TNF receptor-associated factor 6 Toll-like receptor 4 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00206 O43187 O43318 P08571 P0CG47 P0CG48 P62979 P62987 Q15750 Q86XR7 Q8IUC6 Q8N5C8 Q9NYJ8 Q9Y4K3 Q9Y6Y9	CD14 ESOP1 IRAK2 KIAA0733 LY96 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MD2 PRVTIRB RNF85 RPS27A TAB1 TAB2 TAB3 TAK1 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAF6 TRAM TRIF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
TRAIL signaling	CASP8 and FADD-like apoptosis regulator Caspase-10 Caspase-8 FAS-associated death domain protein Tumor necrosis factor ligand superfamily member 10 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 10D	O00220 O14763 O15519 P50591 Q13158 Q14790 Q92851 Q9UBN6	APO2 APO2L CASH CASP10 CASP8 CASP8AP1 CFLAR CLARP DCR2 DR4 DR5 FADD KILLER MCH4 MCH5 MORT1 MRIT TNFRSF10A TNFRSF10B TNFRSF10D TNFSF10 TRAIL TRAILR1 TRAILR2 TRAILR4 TRICK2 TRUNDD ZTNFR9
TRIF-mediated programmed cell death	Caspase-8 FAS-associated death domain protein Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Receptor-interacting serine/threonine-protein kinase 1 Receptor-interacting serine/threonine-protein kinase 3 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 Toll-like receptor 4	O00206 P08571 Q13158 Q13546 Q14790 Q86XR7 Q8IUC6 Q9Y572 Q9Y6Y9	CASP8 CD14 ESOP1 FADD LY96 MCH5 MD2 MORT1 PRVTIRB RIP RIP1 RIP3 RIPK1 RIPK3 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAM TRIF
TRKA activation by NGF	Beta-nerve growth factor High affinity nerve growth factor receptor	P01138 P04629	MTC NGF NGFB NTRK1 TRK TRKA
TRP channels	Mucolipin-1 Mucolipin-2 Mucolipin-3 Short transient receptor potential channel 1 Short transient receptor potential channel 3 Short transient receptor potential channel 4-associated protein Short transient receptor potential channel 4 Short transient receptor potential channel 5 Short transient receptor potential channel 6 Short transient receptor potential channel 7 Transient receptor potential cation channel subfamily A member 1 Transient receptor potential cation channel subfamily M member 1 Transient receptor potential cation channel subfamily M member 2 Transient receptor potential cation channel subfamily M member 3 Transient receptor potential cation channel subfamily M member 4 Transient receptor potential cation channel subfamily M member 5 Transient receptor potential cation channel subfamily M member 6 Transient receptor potential cation channel subfamily M member 7 Transient receptor potential cation channel subfamily M member 8 Transient receptor potential cation channel subfamily V member 1 Transient receptor potential cation channel subfamily V member 2 Transient receptor potential cation channel subfamily V member 3 Transient receptor potential cation channel subfamily V member 4 Transient receptor potential cation channel subfamily V member 5 Transient receptor potential cation channel subfamily V member 6	O75762 O94759 P48995 Q13507 Q7Z2W7 Q7Z4N2 Q8IZK6 Q8NER1 Q8NET8 Q8TD43 Q8TDD5 Q8TEL6 Q96QT4 Q9BX84 Q9GZU1 Q9H1D0 Q9HBA0 Q9HCF6 Q9HCX4 Q9NQA5 Q9NZQ8 Q9UBN4 Q9UL62 Q9Y210 Q9Y5S1	ANKTM1 C20orf188 CHAK1 CHAK2 ECAC1 ECAC2 EREG1 KIAA1616 KNP3 LTRPC1 LTRPC2 LTRPC3 LTRPC4 LTRPC5 LTRPC6 LTRPC7 MCOLN1 MCOLN2 MCOLN3 ML4 MLSN MLSN1 MTR1 TRP1 TRP3 TRP5 TRP6 TRP7 TRPA1 TRPC1 TRPC3 TRPC4 TRPC4AP TRPC5 TRPC6 TRPC7 TRPM1 TRPM2 TRPM3 TRPM4 TRPM5 TRPM6 TRPM7 TRPM8 TRPML1 TRPP8 TRPV1 TRPV2 TRPV3 TRPV4 TRPV5 TRPV6 TRRP4AP VR1 VRL VRL2 VROAC
TWIK related potassium channel (TREK)	Potassium channel subfamily K member 10 Potassium channel subfamily K member 2 Potassium channel subfamily K member 4	O95069 P57789 Q9NYG8	KCNK10 KCNK2 KCNK4 TRAAK TREK TREK1 TREK2
TWIK-related alkaline pH activated K+ channel (TALK)	Potassium channel subfamily K member 16 Potassium channel subfamily K member 17	Q96T54 Q96T55	KCNK16 KCNK17 TALK1 TALK2 TASK4
TWIK-related spinal cord K+ channel (TRESK)	Potassium channel subfamily K member 18	Q7Z418	KCNK18 TRESK TRIK
TWIK-releated acid-sensitive K+ channel (TASK)	Potassium channel subfamily K member 3 Potassium channel subfamily K member 9	O14649 Q9NPC2	KCNK3 KCNK9 TASK TASK1 TASK3

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