GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **251 - 275** of **2090** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism
rRNA processing in the mitochondrion	3-hydroxyacyl-CoA dehydrogenase type-2 Mitochondrial ribonuclease P catalytic subunit Zinc phosphodiesterase ELAC protein 2 tRNA methyltransferase 10 homolog C	O15091 Q7L0Y3 Q99714 Q9BQ52	ELAC2 ERAB HADH2 HPC2 HSD17B10 KIAA0391 MRPP1 MRPP2 MRPP3 PRORP RG9MTD1 SCHAD SDR5C1 TRMT10C XH98G2	Homo sapiens (human)
Cholesterol biosynthesis	3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 Acetyl-CoA acetyltransferase, cytosolic Delta(14)-sterol reductase LBR Delta(14)-sterol reductase TM7SF2 Delta(24)-sterol reductase Diphosphomevalonate decarboxylase Farnesyl pyrophosphate synthase Geranylgeranyl pyrophosphate synthase Hydroxymethylglutaryl-CoA synthase, cytoplasmic Isopentenyl-diphosphate Delta-isomerase 1 Isopentenyl-diphosphate delta-isomerase 2 Lanosterol 14-alpha demethylase Lanosterol synthase Methylsterol monooxygenase 1 Mevalonate kinase Phosphomevalonate kinase Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6 Protein ARV1 Squalene monooxygenase Squalene synthase Sterol regulatory element-binding protein 1 Sterol regulatory element-binding protein 2 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating	O76062 O95749 P14324 P36956 P37268 P48449 P53602 P56937 Q01581 Q03426 Q12772 Q13907 Q14534 Q14739 Q15126 Q15392 Q15738 Q15800 Q16850 Q8IY26 Q9BWD1 Q9BXS1 Q9H2C2	17HSD7 ACAT2 ACTL ANG1 ARV1 BHLHD1 BHLHD2 CYP51 CYP51A1 DESP4 DHCR24 ERG1 ERG25 FDFT1 FDPS FPS GGPS1 H105E3 HMGCS HMGCS1 HSD17B7 IDI1 IDI2 KIAA0018 KIAA1293 LBR LSS MPD MSMO1 MVD MVK NSDHL OSC PDP1 PLPP6 PMKI PMVK PPAPDC2 SC4MOL SDR37C1 SQLE SREBF1 SREBF2 SREBP1 SREBP2 TM7SF2	Homo sapiens (human)
Mitochondrial Fatty Acid Beta-Oxidation	3-ketoacyl-CoA thiolase, mitochondrial Acetyl-coenzyme A thioesterase Acyl carrier protein, mitochondrial Acyl-CoA dehydrogenase family member 10 Acyl-CoA dehydrogenase family member 11 Acyl-CoA-binding domain-containing protein 6 Acyl-CoA-binding domain-containing protein 7 Acyl-CoA-binding protein Acyl-coenzyme A thioesterase 11 Acyl-coenzyme A thioesterase 13 Acyl-coenzyme A thioesterase 1 Acyl-coenzyme A thioesterase 2, mitochondrial Acyl-coenzyme A thioesterase 9, mitochondrial Acyl-coenzyme A thioesterase THEM4 Acyl-coenzyme A thioesterase THEM5 Cytosolic acyl coenzyme A thioester hydrolase Malonyl-CoA-acyl carrier protein transacylase, mitochondrial Medium-chain acyl-CoA ligase ACSF2, mitochondrial Phosphatidylcholine transfer protein Putative cytosolic acyl coenzyme A thioester hydrolase-like	O00154 O14561 P07108 P42765 P49753 Q5T1C6 Q6JQN1 Q6ZUV0 Q709F0 Q86TX2 Q8IVS2 Q8N1Q8 Q8N6N7 Q8WXI4 Q8WYK0 Q96CM8 Q9BR61 Q9NPJ3 Q9UKL6 Q9Y305	ACAA2 ACAD10 ACAD11 ACBD6 ACBD7 ACOT1 ACOT11 ACOT12 ACOT13 ACOT15 ACOT2 ACOT7 ACOT7L ACOT9 ACSF2 BACH BACHL BFIT CACH CACH1 CTE1 CTMP DBI KIAA0707 MCAT MT NDUFAB1 PCTP PTE2 PTE2A STARD15 STARD2 THEA THEM2 THEM4 THEM5	Homo sapiens (human)
alpha-linolenic acid (ALA) metabolism	3-ketoacyl-CoA thiolase, peroxisomal ATP-binding cassette sub-family D member 1 Acyl-CoA (8-3)-desaturase Acyl-CoA 6-desaturase Acyl-coenzyme A thioesterase 8 Long-chain-fatty-acid--CoA ligase 1 Peroxisomal multifunctional enzyme type 2 Sterol carrier protein 2 Very long chain fatty acid elongase 1 Very long chain fatty acid elongase 2 Very long chain fatty acid elongase 3 Very long chain fatty acid elongase 5	O14734 O60427 O95864 P09110 P22307 P33121 P33897 P51659 Q9BW60 Q9HB03 Q9NXB9 Q9NYP7	ABCD1 ACAA ACAA1 ACOT8 ACSL1 ACTEIII ALD CIG30 EDH17B4 ELG3 ELOVL1 ELOVL2 ELOVL3 ELOVL5 FACL1 FACL2 FADS1 FADS2 FADSD5 HSD17B4 LACS LACS1 LACS2 PTE1 PTHIO SCP2 SDR8C1 SSC1 SSC2	Homo sapiens (human)
Beta-oxidation of very long chain fatty acids	3-ketoacyl-CoA thiolase, peroxisomal ATP-binding cassette sub-family D member 1 Acyl-coenzyme A thioesterase 6 Acyl-coenzyme A thioesterase 8 Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] Peroxisomal bifunctional enzyme Peroxisomal multifunctional enzyme type 2 Peroxisomal succinyl-coenzyme A thioesterase	O14734 P09110 P33897 P51659 Q08426 Q3I5F7 Q8N9L9 Q9NUI1	ABCD1 ACAA ACAA1 ACOT4 ACOT6 ACOT8 ACTEIII ALD C14orf42 DECR2 ECHD EDH17B4 EHHADH HSD17B4 PDCR PTE1 PTE2B PTEIB PTHIO SDR17C1 SDR8C1	Homo sapiens (human)
TYSND1 cleaves peroxisomal proteins	3-ketoacyl-CoA thiolase, peroxisomal Alkyldihydroxyacetonephosphate synthase, peroxisomal Peroxisomal acyl-coenzyme A oxidase 1 Peroxisomal leader peptide-processing protease Peroxisomal multifunctional enzyme type 2 Phytanoyl-CoA dioxygenase, peroxisomal Sterol carrier protein 2	O00116 O14832 P09110 P22307 P51659 Q15067 Q2T9J0	ACAA ACAA1 ACOX ACOX1 AGPS EDH17B4 HSD17B4 PAHX PHYH PTHIO SCP2 SDR8C1 TYSND1	Homo sapiens (human)
Sphingolipid de novo biosynthesis	3-ketodihydrosphingosine reductase Broad substrate specificity ATP-binding cassette transporter ABCG2 Casein kinase I isoform gamma-2 Ceramide synthase 1 Ceramide synthase 2 Ceramide synthase 3 Ceramide synthase 4 Ceramide synthase 5 Ceramide synthase 6 Cytochrome b5 type B Fatty acid 2-hydroxylase Multidrug resistance-associated protein 1 ORM1-like protein 1 ORM1-like protein 2 ORM1-like protein 3 Oxysterol-binding protein 1 Phosphatidylcholine Phosphatidylcholine Protein phosphatase 1L Serine palmitoyltransferase 1 Serine palmitoyltransferase 2 Serine palmitoyltransferase 3 Serine palmitoyltransferase small subunit A Serine palmitoyltransferase small subunit B Serine/threonine-protein kinase D1 Serine/threonine-protein kinase D2 Serine/threonine-protein kinase D3 Sphingolipid delta(4)-desaturase DES1 Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 Sphingomyelin synthase-related protein 1 Sphingosine kinase 1 Sphingosine kinase 2 Sphingosine-1-phosphate transporter MFSD2B Sphingosine-1-phosphate transporter SPNS2 Vesicle-associated membrane protein-associated protein A Vesicle-associated membrane protein-associated protein B/C	A6NFX1 O15121 O15269 O15270 O43169 O94806 O95292 P22059 P27544 P33527 P78368 Q06136 Q15139 Q53FV1 Q5SGD2 Q6QHC5 Q6ZMG9 Q7L5A8 Q86VZ5 Q8IU89 Q8IVW8 Q8N138 Q8N5B7 Q8NFR3 Q8NHU3 Q969W0 Q96G23 Q96LT4 Q9BZL6 Q9HA82 Q9NRA0 Q9NUV7 Q9NYA1 Q9P0L0 Q9P0S3 Q9UNQ0	ABCC1 ABCG2 ABCP ADMP BCRP BCRP1 C14orf147 C14orf66 C20orf38 C3orf57 CERS1 CERS2 CERS3 CERS4 CERS5 CERS6 CK1G2 CSNK1G2 CYB5B CYB5M DEGS1 DEGS2 DES1 EPK2 FA2H FAAH FAXDC1 FVT1 KDSR KIAA0526 LAG1 LASS1 LASS2 LASS3 LASS4 LASS5 LASS6 LCB1 LCB2 MFSD2B MLD MOB MRP MRP1 MXR OMB5 ORMDL1 ORMDL2 ORMDL3 OSBP OSBP1 PKD PKD1 PKD2 PP2CE PPM1L PRKCM PRKCN PRKD1 PRKD2 PRKD3 SAMD8 SDR35C1 SGMS1 SGMS2 SK1 SK2 SMS1 SMS2 SPHK SPHK1 SPHK2 SPK SPNS2 SPTLC1 SPTLC2 SPTLC2L SPTLC3 SPTSSA SPTSSB SSSPTA SSSPTB TMEM23 TMSG1 UOG1 VAP33 VAPA VAPB	Homo sapiens (human)
PI3K/AKT Signaling	3-phosphoinositide-dependent protein kinase 1 Acyl-coenzyme A thioesterase THEM4 Amphiregulin B-lymphocyte antigen CD19 Beta-klotho Epidermal growth factor receptor Epigen Estrogen receptor beta Estrogen receptor Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 19 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fms-related tyrosine kinase 3 ligand GRB2-associated-binding protein 1 GRB2-associated-binding protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Insulin receptor substrate 1 Insulin receptor substrate 2 Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-like 1 Interleukin-33 Mast/stem cell growth factor receptor Kit Membrane protein Myeloid differentiation primary response protein MyD88 Nucleoprotein Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Phosphoinositide 3-kinase adapter protein 1 Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit B Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Proline-rich protein 5 Proto-oncogene tyrosine-protein kinase Src Proto-oncogene vav Protransforming growth factor alpha RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Rapamycin-insensitive companion of mTOR Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 2 Receptor tyrosine-protein kinase erbB-2 Receptor-type tyrosine-protein kinase FLT3 Rho-related GTP-binding protein RhoG Serine/threonine-protein kinase Sgk1 Serine/threonine-protein kinase mTOR Striatin T-cell receptor-associated transmembrane adapter 1 T-cell-specific surface glycoprotein CD28 T-lymphocyte activation antigen CD80 T-lymphocyte activation antigen CD86 TNF receptor-associated factor 6 Target of rapamycin complex 2 subunit MAPKAP1 Target of rapamycin complex subunit LST8 Tribbles homolog 3 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lck Tyrosine-protein phosphatase non-receptor type 11	O00141 O00329 O00459 O14511 O14944 O15520 O15530 O43320 O43815 O76093 O95750 O95760 P00533 P01127 P01133 P01135 P03372 P04626 P05230 P06239 P06241 P08581 P08620 P09038 P09619 P0DTC5 P0DTC9 P10721 P10747 P10767 P11487 P12931 P14210 P15153 P15391 P15498 P15514 P16234 P21781 P22455 P27986 P31371 P31749 P31751 P33681 P35070 P35568 P36888 P42081 P42336 P42338 P42345 P49771 P51617 P56975 P63000 P84095 P85299 Q01638 Q02297 Q06124 Q13480 Q5T1C6 Q6PIZ9 Q6R327 Q6UW88 Q6ZUJ8 Q86Z14 Q8WU20 Q8WWG1 Q92569 Q92731 Q96RU7 Q99075 Q99836 Q9BPZ7 Q9BVC4 Q9GZV9 Q9HCT0 Q9NP95 Q9NWZ3 Q9UQC2 Q9Y243 Q9Y4H2 Q9Y4K3	AKT1 AKT2 AKT3 AREG AREGB ARHG BCAP BTC C20orf97 C9orf26 CD135 CD19 CD28 CD28LG CD28LG1 CD28LG2 CD80 CD86 CTMP DER4 DTR DTS EGF EGFR EPGN ERBB ERBB1 ERBB2 EREG ESR ESR1 ESR2 ESTRB FGF1 FGF10 FGF16 FGF18 FGF19 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB FGFR4 FLK2 FLT3 FLT3LG FRAP FRAP1 FRAP2 FRS2 FYN GAB1 GAB2 GBL GGF GRB1 HBEGF HEGFL HER1 HER2 HGF HGL HPTA HRGA HST HST2 HSTF1 HSTF2 HYPF IL1F11 IL1RL1 IL33 INT2 IRAK IRAK1 IRAK4 IRS1 IRS2 JTK2 KGF KIAA0571 KIAA1999 KIT KLB KS3 LAB7 LCK LST8 M MAPKAP1 MET MIP1 MLN19 MLST8 MTOR MYD88 N NDF NEU NFHEV NGL NIPK NR3A1 NR3A2 NRG1 NRG2 NRG3 NRG4 NTAK PDGF2 PDGFB PDGFR PDGFR1 PDGFR2 PDGFRA PDGFRB PDK1 PDPK1 PIK3AP1 PIK3C1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PKB PKBG PROTOR1 PRR5 PTP2C PTPN11 RAC RAC1 RAC2 RAFT1 RAPT1 RHEPDGFRA RHOG RICTOR RNF85 SCFR SDGF SGK SGK1 SHPTP2 SIN1 SIS SKIP3 SMDF SRC SRC1 ST2 STK1 STRN T1 TC25 TCRIM TGFA THEM4 TKF TRAF6 TRAT1 TRB3 TRIB3 VAV VAV1	Homo sapiens (human)
VEGFR2 mediated vascular permeability	3-phosphoinositide-dependent protein kinase 1 Acyl-coenzyme A thioesterase THEM4 Cadherin-5 Calmodulin-1 Catenin alpha-1 Catenin beta-1 Catenin delta-1 Caveolin-1 Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Heat shock protein HSP 90-alpha Junction plakoglobin Membrane protein Nitric oxide synthase 3 Nucleoprotein Proline-rich protein 5 Proto-oncogene vav RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Rapamycin-insensitive companion of mTOR Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Serine/threonine-protein kinase mTOR Target of rapamycin complex 2 subunit MAPKAP1 Target of rapamycin complex subunit LST8 Tribbles homolog 3	O15530 O60716 O75914 P07900 P0DP23 P0DTC5 P0DTC9 P14923 P15498 P29474 P31749 P31751 P33151 P35221 P35222 P42345 P52735 P63000 P85299 Q03135 Q13153 Q13177 Q5T1C6 Q6R327 Q96RU7 Q9BPZ7 Q9BVC4 Q9UKW4 Q9Y243	AKT1 AKT2 AKT3 C20orf97 CALM CALM1 CAM CAM1 CAV CAV1 CDH5 CTMP CTNNA1 CTNNB CTNNB1 CTNND1 CTNNG DP3 FRAP FRAP1 FRAP2 GBL HSP90A HSP90AA1 HSPC1 HSPCA JUP KIAA0384 KIAA1999 LST8 M MAPKAP1 MIP1 MLST8 MTOR N NIPK NOS3 OPHN3 PAK1 PAK2 PAK3 PDK1 PDPK1 PKB PKBG PROTOR1 PRR5 RAC RAC1 RAFT1 RAPT1 RICTOR SIN1 SKIP3 TC25 THEM4 TRB3 TRIB3 VAV VAV1 VAV2 VAV3	Homo sapiens (human)
CD28 dependent PI3K/Akt signaling	3-phosphoinositide-dependent protein kinase 1 Acyl-coenzyme A thioesterase THEM4 Membrane protein Mitogen-activated protein kinase kinase kinase 14 Mitogen-activated protein kinase kinase kinase 8 Nucleoprotein Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Proline-rich protein 5 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Rapamycin-insensitive companion of mTOR Serine/threonine-protein kinase mTOR T-cell-specific surface glycoprotein CD28 T-lymphocyte activation antigen CD80 T-lymphocyte activation antigen CD86 Target of rapamycin complex 2 subunit MAPKAP1 Target of rapamycin complex subunit LST8 Tribbles homolog 3 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lck	O00459 O15530 P06239 P06241 P0DTC5 P0DTC9 P10747 P27986 P31749 P31751 P33681 P41279 P42081 P42336 P42345 P85299 Q5T1C6 Q6R327 Q92569 Q96RU7 Q99558 Q9BPZ7 Q9BVC4 Q9Y243	AKT1 AKT2 AKT3 C20orf97 CD28 CD28LG CD28LG1 CD28LG2 CD80 CD86 COT CTMP ESTF FRAP FRAP1 FRAP2 FYN GBL GRB1 KIAA1999 LAB7 LCK LST8 M MAP3K14 MAP3K8 MAPKAP1 MIP1 MLST8 MTOR N NIK NIPK PDK1 PDPK1 PIK3CA PIK3R1 PIK3R2 PIK3R3 PKB PKBG PROTOR1 PRR5 RAC RAFT1 RAPT1 RICTOR SIN1 SKIP3 THEM4 TRB3 TRIB3	Homo sapiens (human)
Activation of PKB	3-phosphoinositide-dependent protein kinase 1 Acyl-coenzyme A thioesterase THEM4 RAC-beta serine/threonine-protein kinase Tribbles homolog 3	O15530 P31751 Q5T1C6 Q96RU7	AKT2 C20orf97 CTMP NIPK PDK1 PDPK1 SKIP3 THEM4 TRB3 TRIB3	Homo sapiens (human)
Integrin signaling	3-phosphoinositide-dependent protein kinase 1 Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin Focal adhesion kinase 1 Integrin alpha-IIb Integrin beta-3 Proto-oncogene tyrosine-protein kinase Src RAC-alpha serine/threonine-protein kinase RAS guanyl-releasing protein 1 RAS guanyl-releasing protein 2 Rap guanine nucleotide exchange factor 3 Rap guanine nucleotide exchange factor 4 Ras-related protein Rap-1A Ras-related protein Rap-1b SHC-transforming protein 1 Talin-1 Tyrosine-protein kinase CSK Tyrosine-protein kinase SYK Tyrosine-protein phosphatase non-receptor type 1 von Willebrand factor	O15530 O95267 O95398 P02671 P02675 P02679 P02751 P04275 P05106 P08514 P12931 P18031 P29353 P31749 P41240 P43405 P61224 P62834 Q05397 Q7LDG7 Q7Z5R6 Q8WZA2 Q9Y490	AKT1 APBB1IP CDC25L CGEF1 CGEF2 CSK EPAC EPAC1 EPAC2 F8VWF FAK FAK1 FGA FGB FGG FN FN1 GP2B GP3A ITGA2B ITGAB ITGB3 KIAA1027 KREV1 MCG7 PDK1 PDPK1 PKB PREL1 PTK2 PTP1B PTPN1 RAC RAP1A RAP1B RAPGEF3 RAPGEF4 RARP1 RASGRP RASGRP1 RASGRP2 RIAM SHC SHC1 SHCA SRC SRC1 SYK TLN TLN1 VWF	Homo sapiens (human)
Constitutive Signaling by AKT1 E17K in Cancer	3-phosphoinositide-dependent protein kinase 1 Bcl2-associated agonist of cell death Caspase-9 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B E3 ubiquitin-protein ligase Mdm2 Forkhead box protein O1 Forkhead box protein O3 Forkhead box protein O4 Forkhead box protein O6 Glycogen synthase kinase-3 alpha Glycogen synthase kinase-3 beta Inhibitor of nuclear factor kappa-B kinase subunit alpha Nuclear receptor subfamily 4immunitygroup A member 1 Proline-rich AKT1 substrate 1 Proline-rich protein 5 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Rapamycin-insensitive companion of mTOR Ribosomal protein S6 kinase beta-2 Serine/threonine-protein kinase mTOR Target of rapamycin complex 2 subunit MAPKAP1 Target of rapamycin complex subunit LST8 Tuberin	A8MYZ6 O15111 O15530 O43524 P22736 P31749 P31751 P38936 P42345 P46527 P49815 P49840 P49841 P55211 P85299 P98177 Q00987 Q12778 Q6R327 Q92934 Q96B36 Q9BPZ7 Q9BVC4 Q9UBS0 Q9Y243	AFX AFX1 AKT1 AKT1S1 AKT2 AKT3 BAD BBC6 BCL2L8 CAP20 CASP9 CDKN1 CDKN1A CDKN1B CHUK CIP1 FKHR FKHRL1 FOXO1 FOXO1A FOXO3 FOXO3A FOXO4 FOXO6 FRAP FRAP1 FRAP2 GBL GFRP1 GSK3A GSK3B HMR IKKA KIAA1999 KIP1 LST8 MAPKAP1 MCH6 MDA6 MDM2 MIP1 MLLT7 MLST8 MTOR NAK1 NR4A1 PDK1 PDPK1 PIC1 PKB PKBG PRAS40 PROTOR1 PRR5 RAC RAFT1 RAPT1 RICTOR RPS6KB2 SDI1 SIN1 STK14B TCF16 TSC2 TSC4 WAF1 p27	Homo sapiens (human)
Regulation of TP53 Degradation	3-phosphoinositide-dependent protein kinase 1 Cellular tumor antigen p53 Cyclin-A1 Cyclin-A2 Cyclin-G1 Cyclin-dependent kinase 1 Cyclin-dependent kinase 2 Death domain-associated protein 6 E3 ubiquitin-protein ligase Mdm2 E3 ubiquitin-protein ligase RNF34 E3 ubiquitin-protein ligase rififylin PHD finger protein 20 Polyubiquitin-B Polyubiquitin-C Proline-rich protein 5 Protein Mdm4 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Rapamycin-insensitive companion of mTOR Serine-protein kinase ATM Serine/threonine-protein kinase Chk2 Serine/threonine-protein kinase Sgk1 Serine/threonine-protein kinase mTOR Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Target of rapamycin complex 2 subunit MAPKAP1 Target of rapamycin complex subunit LST8 Tumor suppressor ARF Ubiquitin carboxyl-terminal hydrolase 2 Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00141 O15151 O15530 O75604 O96017 P04637 P06493 P0CG47 P0CG48 P20248 P24941 P30153 P30154 P31749 P31751 P42345 P51959 P62714 P62979 P62987 P67775 P78396 P85299 Q00987 Q13315 Q13362 Q6R327 Q8N726 Q8WZ73 Q93009 Q969K3 Q9BPZ7 Q9BVC4 Q9BVI0 Q9UER7 Q9Y243	AKT1 AKT2 AKT3 ATM BING2 C20orf104 CCN1 CCNA CCNA1 CCNA2 CCNG CCNG1 CDC2 CDC28A CDK1 CDK2 CDKN1 CDKN2 CDKN2A CDS1 CHEK2 CHK2 CYCG1 DAP6 DAXX FRAP FRAP1 FRAP2 GBL GLEA2 HAUSP HCA58 KIAA0044 KIAA1999 LST8 MAPKAP1 MDM2 MDM4 MDMX MIP1 MLM MLST8 MTOR NZF P34CDC2 P53 PDK1 PDPK1 PHF20 PKB PKBG PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5C PROTOR1 PRR5 RAC RAD53 RAFT1 RAPT1 RFFL RICTOR RNF189 RNF34 RNF34L RPS27A SGK SGK1 SIN1 TP53 TZP UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBP41 USP2 USP7	Homo sapiens (human)
Role of LAT2/NTAL/LAB on calcium mobilization	3-phosphoinositide-dependent protein kinase 1 GRB2-associated-binding protein 2 IGHV7-81 protein Immunoglobulin heavy constant epsilon Immunoglobulin heavy variable 1-2 Immunoglobulin heavy variable 1-46 Immunoglobulin heavy variable 1-69 Immunoglobulin heavy variable 2-5 Immunoglobulin heavy variable 2-70 Immunoglobulin heavy variable 3-11 Immunoglobulin heavy variable 3-13 Immunoglobulin heavy variable 3-23 Immunoglobulin heavy variable 3-30 Immunoglobulin heavy variable 3-33 Immunoglobulin heavy variable 3-48 Immunoglobulin heavy variable 3-53 Immunoglobulin heavy variable 3-7 Immunoglobulin heavy variable 3-9 Immunoglobulin heavy variable 4-34 Immunoglobulin heavy variable 4-39 Immunoglobulin heavy variable 4-59 Immunoglobulin kappa constant Immunoglobulin kappa variable 1-12 Immunoglobulin kappa variable 1-16 Immunoglobulin kappa variable 1-17 Immunoglobulin kappa variable 1-33 Immunoglobulin kappa variable 1-39 Immunoglobulin kappa variable 1-5 Immunoglobulin kappa variable 1D-12 Immunoglobulin kappa variable 1D-16 Immunoglobulin kappa variable 1D-33 Immunoglobulin kappa variable 1D-39 Immunoglobulin kappa variable 2-28 Immunoglobulin kappa variable 2-29 Immunoglobulin kappa variable 2-30 Immunoglobulin kappa variable 2D-28 Immunoglobulin kappa variable 2D-30 Immunoglobulin kappa variable 2D-40 Immunoglobulin kappa variable 3-11 Immunoglobulin kappa variable 3-15 Immunoglobulin kappa variable 3-20 Immunoglobulin kappa variable 3D-20 Immunoglobulin kappa variable 4-1 Immunoglobulin kappa variable 5-2 Immunoglobulin lambda constant 1 Immunoglobulin lambda constant 2 Immunoglobulin lambda constant 3 Immunoglobulin lambda constant 6 Immunoglobulin lambda constant 7 Immunoglobulin lambda variable 1-40 Immunoglobulin lambda variable 1-44 Immunoglobulin lambda variable 1-47 Immunoglobulin lambda variable 1-51 Immunoglobulin lambda variable 2-11 Immunoglobulin lambda variable 2-14 Immunoglobulin lambda variable 2-23 Immunoglobulin lambda variable 2-8 Immunoglobulin lambda variable 3-19 Immunoglobulin lambda variable 3-1 Immunoglobulin lambda variable 3-21 Immunoglobulin lambda variable 3-25 Immunoglobulin lambda variable 3-27 Immunoglobulin lambda variable 6-57 Immunoglobulin lambda variable 7-43 Immunolglobulin kappa light chain variable region L22 (Fragment) Linker for activation of T-cells family member 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Son of sevenless homolog 1 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK UGa8H (Fragment) V1-11 protein (Fragment) V1-13 protein (Fragment) V1-16 protein (Fragment) V1-20 protein (Fragment) V1-3 protein (Fragment) V1-5 protein (Fragment) V1-7 protein (Fragment) V1-9 protein (Fragment) V2-11 protein (Fragment) V2-15 protein (Fragment) V2-17 protein (Fragment) V2-19 protein (Fragment) V2-8 protein (Fragment) V3-2 protein (Fragment) V3-3 protein (Fragment) V3-4 protein (Fragment) V4-1 protein (Fragment) V4-2 protein (Fragment) V4-6 protein (Fragment) V5-1 protein (Fragment) V5-4 protein (Fragment) V5-6 protein (Fragment)	A0A075B6P5 A0A075B6S6 A0A0C4DH25 A0A0C4DH73 A0M8Q6 A2KUC3 A2NJV5 A2NXD2 O00459 O15530 P01593 P01594 P01597 P01599 P01601 P01602 P01611 P01614 P01615 P01619 P01624 P01699 P01700 P01701 P01703 P01704 P01705 P01706 P01709 P01714 P01715 P01717 P01718 P01721 P01742 P01743 P01762 P01763 P01764 P01766 P01767 P01768 P01772 P01780 P01782 P01814 P01817 P01824 P01825 P01834 P01854 P04211 P04430 P04432 P04433 P06241 P06310 P06312 P06315 P06331 P07948 P0CF74 P0CG04 P0DOY2 P0DOY3 P23083 P27986 P42336 P42338 P43405 P80748 Q07889 Q5NV61 Q5NV62 Q5NV64 Q5NV65 Q5NV66 Q5NV67 Q5NV68 Q5NV69 Q5NV75 Q5NV79 Q5NV80 Q5NV81 Q5NV82 Q5NV83 Q5NV84 Q5NV85 Q5NV86 Q5NV87 Q5NV89 Q5NV90 Q5NV91 Q5NV92 Q6PIL0 Q9GZY6 Q9UQC2	FYN GAB2 GRB1 IGHE IGHV IGHV1-2 IGHV1-46 IGHV1-69 IGHV2-5 IGHV2-70 IGHV3-11 IGHV3-13 IGHV3-23 IGHV3-30 IGHV3-33 IGHV3-48 IGHV3-53 IGHV3-7 IGHV3-9 IGHV4-34 IGHV4-39 IGHV4-59 IGHV7-81 IGKC IGKV1-12 IGKV1-16 IGKV1-17 IGKV1-33 IGKV1-39 IGKV1-5 IGKV1D-12 IGKV1D-16 IGKV1D-33 IGKV1D-39 IGKV2-28 IGKV2-29 IGKV2-30 IGKV2D-28 IGKV2D-30 IGKV2D-40 IGKV3-11 IGKV3-15 IGKV3-20 IGKV3D-20 IGKV4-1 IGKV5-2 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7 IGLV IGLV1-40 IGLV1-44 IGLV1-47 IGLV1-51 IGLV2-11 IGLV2-14 IGLV2-23 IGLV2-8 IGLV3-1 IGLV3-19 IGLV3-21 IGLV3-25 IGLV3-27 IGLV6-57 IGLV7-43 JTK8 KIAA0571 LAB LAT2 LYN NTAL PDK1 PDPK1 PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 SOS1 SYK V1-11 V1-13 V1-16 V1-20 V1-3 V1-5 V1-7 V1-9 V2-11 V2-15 V2-17 V2-19 V2-8 V3-2 V3-3 V3-4 V4-1 V4-2 V4-6 V5-1 V5-4 V5-6 WBS15 WBSCR15 WBSCR5	Homo sapiens (human)
Estrogen-stimulated signaling through PRKCZ	3-phosphoinositide-dependent protein kinase 1 GTPase HRas GTPase NRas Mitogen-activated protein kinase 1 Protein kinase C zeta type	O15530 P01111 P01112 P28482 Q05513	ERK2 HRAS HRAS1 MAPK1 NRAS PDK1 PDPK1 PKC2 PRKCZ PRKM1 PRKM2	Homo sapiens (human)
G beta:gamma signalling through PI3Kgamma	3-phosphoinositide-dependent protein kinase 1 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Phosphoinositide 3-kinase regulatory subunit 5 Phosphoinositide 3-kinase regulatory subunit 6 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Transforming protein RhoA	O14610 O14775 O15530 O60262 P16520 P31749 P31751 P48736 P50150 P50151 P59768 P61586 P61952 P62873 P62879 P63211 P63215 P63218 Q5UE93 Q8WYR1 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08 Q9Y243	AKT1 AKT2 AKT3 ARH12 ARHA C17orf38 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 PDK1 PDPK1 PIK3CG PIK3R5 PIK3R6 PKB PKBG RAC RHO12 RHOA	Homo sapiens (human)
RSK activation	3-phosphoinositide-dependent protein kinase 1 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Ribosomal protein S6 kinase alpha-1 Ribosomal protein S6 kinase alpha-2 Ribosomal protein S6 kinase alpha-3 Ribosomal protein S6 kinase alpha-6	O15530 P27361 P28482 P51812 Q15349 Q15418 Q9UK32	ERK1 ERK2 ISPK1 MAPK1 MAPK3 MAPKAPK1A MAPKAPK1B MAPKAPK1C PDK1 PDPK1 PRKM1 PRKM2 PRKM3 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA6 RSK1 RSK2 RSK3 RSK4	Homo sapiens (human)
Vitamin B5 (pantothenate) metabolism	4'-phosphopantetheine phosphatase Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 Fatty acid synthase L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Mitochondrial coenzyme A diphosphatase NUDT8 Mitochondrial coenzyme A transporter SLC25A42 PDZ domain-containing protein 11 Pantetheinase Pantetheine hydrolase VNN2 Sodium-dependent multivitamin transporter Solute carrier family 25 member 16	O14638 O95497 O95498 P16260 P22413 P49327 Q13822 Q5EBL8 Q86VD7 Q8WV74 Q9NRN7 Q9NVE7 Q9Y289	AASDHPPT AIPP1 ATX ENPP1 ENPP2 ENPP3 FAS FASN GDA M6S1 NPPS NUDT8 PANK4 PC1 PDNP1 PDNP2 PDNP3 PDZD11 PDZK11 PISP SLC25A16 SLC25A42 SLC5A6 SMVT VNN1 VNN2	Homo sapiens (human)
Degradation of GABA	4-aminobutyrate aminotransferase, mitochondrial Succinate-semialdehyde dehydrogenase, mitochondrial	P51649 P80404	ABAT ALDH5A1 GABAT SSADH	Homo sapiens (human)
Mitochondrial protein import	4-hydroxybenzoate polyprenyltransferase, mitochondrial 60 kDa heat shock protein, mitochondrial ADP/ATP translocase 1 ADP/ATP translocase 3 ATP synthase F(0) complex subunit C1, mitochondrial ATP synthase subunit alpha, mitochondrial ATP synthase subunit beta, mitochondrial Aconitate hydratase, mitochondrial COX assembly mitochondrial protein 2 homolog Citrate synthase, mitochondrial Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 Coiled-coil-helix-coiled-coil-helix domain-containing protein 5 Coiled-coil-helix-coiled-coil-helix domain-containing protein 7 Cx9C motif-containing protein 4 Cytochrome c oxidase assembly factor 4 homolog, mitochondrial Cytochrome c oxidase assembly factor 6 homolog Cytochrome c oxidase assembly protein COX19 Cytochrome c oxidase copper chaperone Cytochrome c1, heme protein, mitochondrial Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial FAD-linked sulfhydryl oxidase ALR Frataxin, mitochondrial GrpE protein homolog 1, mitochondrial GrpE protein homolog 2, mitochondrial Iron-sulfur cluster co-chaperone protein HscB Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial MICOS complex subunit MIC19 Metaxin-1 Metaxin-2 Mitochondrial chaperone BCS1 Mitochondrial import inner membrane translocase subunit TIM14 Mitochondrial import inner membrane translocase subunit TIM16 Mitochondrial import inner membrane translocase subunit TIM44 Mitochondrial import inner membrane translocase subunit TIM50 Mitochondrial import inner membrane translocase subunit Tim10 B Mitochondrial import inner membrane translocase subunit Tim10 Mitochondrial import inner membrane translocase subunit Tim13 Mitochondrial import inner membrane translocase subunit Tim17-A Mitochondrial import inner membrane translocase subunit Tim17-B Mitochondrial import inner membrane translocase subunit Tim21 Mitochondrial import inner membrane translocase subunit Tim22 Mitochondrial import inner membrane translocase subunit Tim23 Mitochondrial import inner membrane translocase subunit Tim8 A Mitochondrial import inner membrane translocase subunit Tim8 B Mitochondrial import inner membrane translocase subunit Tim9 Mitochondrial import receptor subunit TOM20 homolog Mitochondrial import receptor subunit TOM22 homolog Mitochondrial import receptor subunit TOM40 homolog Mitochondrial import receptor subunit TOM5 homolog Mitochondrial import receptor subunit TOM6 homolog Mitochondrial import receptor subunit TOM7 homolog Mitochondrial import receptor subunit TOM70 Mitochondrial intermembrane space import and assembly protein 40 Mitochondrial-processing peptidase subunit alpha Mitochondrial-processing peptidase subunit beta NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial Ornithine transcarbamylase, mitochondrial Presequence protease, mitochondrial Probable D-lactate dehydrogenase, mitochondrial Sorting and assembly machinery component 50 homolog Stress-70 protein, mitochondrial Tafazzin Voltage-dependent anion-selective channel protein 1	O14925 O43615 O60220 O60830 O75390 O75431 O75439 O75746 O94826 O95169 O96008 P00480 P05496 P06576 P08574 P10809 P12235 P12236 P21796 P25705 P38646 P51553 P55789 P56277 P62072 Q10713 Q13505 Q14061 Q15388 Q16595 Q16635 Q3ZCQ8 Q49B96 Q5JRX3 Q5JTJ3 Q86WU2 Q8IWL3 Q8N4H5 Q8N4Q1 Q8TAA5 Q8WYQ3 Q96B49 Q96DA6 Q96H96 Q99595 Q99798 Q9BSY4 Q9BUK0 Q9BVV7 Q9HAV7 Q9NRP2 Q9NS69 Q9NX63 Q9NYJ1 Q9P0U1 Q9UJS0 Q9Y276 Q9Y3D7 Q9Y512 Q9Y584 Q9Y5J6 Q9Y5J7 Q9Y5J9 Q9Y5L4 Q9Y6H1	AAC1 AAC3 ACO2 AGC1 ALR ANT1 ANT3 ARALAR1 ATP5A ATP5A1 ATP5AL2 ATP5B ATP5F1A ATP5F1B ATP5G1 ATP5MC1 ATPM ATPMB ATPSB BCS1 BCS1L C16orf61 C18orf55 C19orf1 C1orf31 C22orf16 C2orf9 C6.1B C7orf17 C9orf105 CHCHD10 CHCHD2 CHCHD3 CHCHD4 CHCHD5 CHCHD7 CHCHD8 CL640 CMC2 CMC4 COA4 COA6 COQ2 COX17 COX19 CS CYC1 DDP DDP1 DDP2 DDPL DNAJC19 DNAJC20 E2IG2 EFE2 FRDA FXC1 FXN G4.5 GFER GREPEL1 GRP75 GRPEL1 GRPEL2 HERV1 HPO HSC20 HSCB HSP60 HSPA9 HSPA9B HSPD1 IDH3G INPP5E KIAA0016 KIAA0123 KIAA0719 KIAA1104 LDHD MAGMAS MIA40 MIC19 MIMT17 MIMT44 MINOS3 MP1 MPPA MPPB MTCP1 MTCP1NB MTX MTX1 MTX2 MTXN NDUFB8 OBTP OTC PAM16 PEREC1 PITRM1 PMPCA PMPCB PREP SAM50 SAMM50 SLC25A12 SLC25A13 SLC25A4 SLC25A6 TAFAZZIN TAZ TEX4 TIM10 TIM13B TIM14 TIM16 TIM17 TIM17A TIM17B TIM21 TIM22 TIM23 TIM44 TIM50 TIM8A TIM8B TIM9 TIM9A TIM9B TIMM10 TIMM10B TIMM13 TIMM13A TIMM13B TIMM14 TIMM16 TIMM17 TIMM17A TIMM17B TIMM21 TIMM22 TIMM23 TIMM44 TIMM50 TIMM8A TIMM8B TIMM9 TIMM9A TIMM9B TOM22 TOM40 TOM5 TOM6 TOM7 TOM70 TOMM07 TOMM20 TOMM22 TOMM40 TOMM5 TOMM6 TOMM7 TOMM70 TOMM70A VDAC VDAC1 X25 mt-HSP70	Homo sapiens (human)
Tyrosine catabolism	4-hydroxyphenylpyruvate dioxygenase Fumarylacetoacetase Homogentisate 1,2-dioxygenase Maleylacetoacetate isomerase Tyrosine aminotransferase	O43708 P16930 P17735 P32754 Q93099	FAH GSTZ1 HGD HGO HPD MAAI PPD TAT	Homo sapiens (human)
Carnitine synthesis	4-trimethylaminobutyraldehyde dehydrogenase Gamma-butyrobetaine dioxygenase Serine hydroxymethyltransferase, cytosolic Trimethyllysine dioxygenase, mitochondrial	O75936 P34896 P49189 Q9NVH6	ALDH4 ALDH7 ALDH9 ALDH9A1 BBH BBOX BBOX1 SHMT1 TMLH TMLHE	Homo sapiens (human)
Fanconi Anemia Pathway	5' exonuclease Apollo ATR-interacting protein Centromere protein S Centromere protein X Crossover junction endonuclease EME1 Crossover junction endonuclease MUS81 DNA cross-link repair 1A protein DNA excision repair protein ERCC-1 DNA polymerase nu DNA repair endonuclease XPF E3 ubiquitin-protein ligase FANCL Fanconi anemia core complex-associated protein 100 Fanconi anemia core complex-associated protein 20 Fanconi anemia core complex-associated protein 24 Fanconi anemia group A protein Fanconi anemia group B protein Fanconi anemia group C protein Fanconi anemia group D2 protein Fanconi anemia group E protein Fanconi anemia group F protein Fanconi anemia group G protein Fanconi anemia group I protein Fanconi anemia group M protein Fanconi-associated nuclease 1 Polyubiquitin-B Polyubiquitin-C Probable crossover junction endonuclease EME2 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Serine/threonine-protein kinase ATR Structure-specific endonuclease subunit SLX1 Structure-specific endonuclease subunit SLX4 Ubiquitin carboxyl-terminal hydrolase 1 Ubiquitin-conjugating enzyme E2 T Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein WD repeat-containing protein 48	A4GXA9 A8MT69 O15287 O15360 O94782 P07992 P0CG47 P0CG48 P15927 P27694 P35244 P62979 P62987 Q00597 Q0VG06 Q13535 Q6NZ36 Q6PJP8 Q7Z5Q5 Q8IY92 Q8IYD8 Q8N2Z9 Q8NB91 Q8TAF3 Q8WXE1 Q92889 Q96AY2 Q96NY9 Q9BQ83 Q9BTP7 Q9BXW9 Q9H816 Q9HB96 Q9NPD8 Q9NPI8 Q9NVI1 Q9NW38 Q9Y2M0	AGS1 APITD1 ATR ATRIP BTBD12 C17orf70 C19orf40 C1orf86 CENPS CENPX DCLRE1A DCLRE1B EME1 EME2 ERCC1 ERCC11 ERCC4 FAA FAAP10 FAAP100 FAAP16 FAAP20 FAAP24 FAC FACA FACC FACD FACE FAN1 FANCA FANCB FANCC FANCD2 FANCE FANCF FANCG FANCH FANCI FANCL FANCM FRP1 GIYD1 GIYD2 KIAA0086 KIAA1018 KIAA1449 KIAA1596 KIAA1784 KIAA1794 KIAA1987 MHF1 MHF2 MMS4 MTMR15 MUS81 PHF9 POLN REPA1 REPA2 REPA3 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A SLX1 SLX1A SLX1B SLX4 SNM1 SNM1A SNM1B STRA13 UAF1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBE2T USP1 WDR48 XPF XRCC9	Homo sapiens (human)
Pyrimidine catabolism	5'(3')-deoxyribonucleotidase, cytosolic type 5'(3')-deoxyribonucleotidase, mitochondrial 5'-nucleotidase Alanine--glyoxylate aminotransferase 2, mitochondrial Beta-ureidopropionase Cytosolic 5'-nucleotidase 1A Dihydropyrimidinase Dihydropyrimidine dehydrogenase [NADP(+)] Thymidine phosphorylase Uridine phosphorylase 1 Uridine phosphorylase 2	O95045 P19971 P21589 Q12882 Q14117 Q16831 Q8TCD5 Q9BXI3 Q9BYV1 Q9NPB1 Q9UBR1	AGT2 AGXT2 BUP1 DNT1 DNT2 DPYD DPYS ECGF1 NT5 NT5C NT5C1A NT5E NT5M NTE TYMP UMPH2 UP UPB1 UPP1 UPP2	Homo sapiens (human)

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