GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **476 - 500** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Separation of Sister Chromatids	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Aurora kinase B B9 domain-containing protein 2 Baculoviral IAP repeat-containing protein 5 Borealin CAP-Gly domain-containing linker protein 1 CLIP-associating protein 1 CLIP-associating protein 2 Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Centromere protein C Centromere protein F Centromere protein H Centromere protein I Centromere protein K Centromere protein L Centromere protein M Centromere protein N Centromere protein O Centromere protein P Centromere protein Q Centromere protein R Centromere protein S Centromere protein T Centromere protein U Centromere-associated protein E Centromere/kinetochore protein zw10 homolog Cohesin subunit SA-1 Cohesin subunit SA-2 Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 Cytoskeleton-associated protein 5 DNA excision repair protein ERCC-6-like Double-strand-break repair protein rad21 homolog Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic E3 SUMO-protein ligase RanBP2 Exportin-1 Histone H3-like centromeric protein A Inner centromere protein Kinesin-like protein KIF18A Kinesin-like protein KIF2A Kinesin-like protein KIF2B Kinesin-like protein KIF2C Kinetochore protein NDC80 homolog Kinetochore protein Nuf2 Kinetochore protein Spc24 Kinetochore protein Spc25 Kinetochore scaffold 1 Kinetochore-associated protein 1 Kinetochore-associated protein DSN1 homolog Kinetochore-associated protein NSL1 homolog Microtubule-associated protein RP/EB family member 1 Mitotic checkpoint protein BUB3 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Mitotic checkpoint serine/threonine-protein kinase BUB1 Mitotic spindle assembly checkpoint protein MAD1 Mitotic spindle assembly checkpoint protein MAD2A Nuclear distribution protein nudE homolog 1 Nuclear distribution protein nudE-like 1 Nuclear migration protein nudC Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup85 Nucleoporin Nup37 Nucleoporin Nup43 Platelet-activating factor acetylhydrolase IB subunit beta Polyamine-modulated factor 1 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein ELYS Protein MIS12 homolog Protein RCC2 Protein SEC13 homolog Protein Spindly Protein zwilch homolog Ran GTPase-activating protein 1 Securin Separin Serine/threonine-protein kinase PLK1 Serine/threonine-protein kinase TAO1 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Shugoshin 1 Shugoshin 2 Sister chromatid cohesion protein PDS5 homolog A Sister chromatid cohesion protein PDS5 homolog B Small ribosomal subunit protein eS27 Sororin Spindle and kinetochore-associated protein 1 Spindle and kinetochore-associated protein 2 Structural maintenance of chromosomes protein 1A Structural maintenance of chromosomes protein 3 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Wings apart-like protein homolog ZW10 interactor	A5LHX3 O00139 O00231 O00232 O00233 O00487 O00762 O14576 O14777 O14818 O14980 O15392 O43237 O43242 O43264 O43683 O43684 O60216 O60566 O75122 O75832 O95229 O95997 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P30153 P30154 P30260 P30622 P35998 P36873 P40306 P42677 P43034 P43686 P46060 P48556 P49450 P49454 P49720 P49721 P49792 P50748 P51665 P51668 P51965 P53350 P55036 P55735 P57740 P60006 P60896 P60900 P61289 P62191 P62195 P62333 P62714 P62979 P62987 P63167 P67775 Q02224 Q03188 Q06323 Q12769 Q12834 Q13042 Q13200 Q13257 Q13352 Q13362 Q13409 Q14008 Q14204 Q14674 Q14683 Q14738 Q14997 Q15008 Q15172 Q15173 Q15691 Q16401 Q16537 Q16763 Q29RF7 Q2NKX8 Q53HL2 Q562F6 Q5FBB7 Q6IPU0 Q6P1K2 Q71F23 Q7L2Z9 Q7L7X3 Q7Z460 Q7Z5K2 Q8N0S6 Q8N2Z9 Q8N3U4 Q8N4N8 Q8NBT2 Q8NFH3 Q8NFH4 Q8NG31 Q8NHZ8 Q8NI77 Q8TAA3 Q8WUM0 Q8WVK7 Q8WVM7 Q8WYP5 Q92530 Q92674 Q96BD8 Q96BT3 Q96DE5 Q96EA4 Q96FF9 Q96FJ2 Q96GD4 Q96H22 Q96IY1 Q99436 Q99460 Q99661 Q9BPU9 Q9BS16 Q9BU64 Q9BW27 Q9BZD4 Q9GZM8 Q9H081 Q9H1A4 Q9H3R5 Q9H410 Q9H900 Q9HBM1 Q9NQS7 Q9NSP4 Q9NTI5 Q9NXR1 Q9NYG5 Q9P258 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UL46 Q9UM13 Q9UNM6 Q9UQE7 Q9Y266 Q9Y6D9 Q9Y6G9	AHCTF1 AIK2 AIM1 AIRK2 ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 API4 APITD1 APRIN ARK2 AS3 AURKB B9D2 BAM BIRC5 BMH BUB1 BUB1B BUB1L BUB3 BUBR1 C10orf104 C11orf51 C16orf56 C16orf60 C18orf24 C1orf155 C1orf48 C20orf172 C22orf18 C6orf139 C7orf76 C9orf17 CASC5 CCDC99 CDC16 CDC20 CDC23 CDC26 CDC27 CDCA1 CDCA5 CDCA8 CENP-27 CENPA CENPC CENPC1 CENPE CENPF CENPH CENPI CENPK CENPL CENPM CENPN CENPO CENPP CENPQ CENPR CENPS CENPT CENPU CKAP5 CLASP1 CLASP2 CLIP1 CRM1 CSPG6 CYLN1 D0S1430E D17S978E D3S1231E DHC1 DLC1 DLC2 DNCH1 DNCI1 DNCI2 DNCIC1 DNCIC2 DNCL DNCL1 DNCLC1 DNCLI1 DNCLI2 DNECL DSN1 DSS1 DXS423E DYHC DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 E2EPF EAP1 ELYS EOPA ERCC6L ESP1 ESPL1 FAAP16 FAM33A FOE FSHPRH1 HC2 HC3 HC8 HC9 HDLC1 HEC HEC1 HR21 HSPC IAP4 ICEN19 ICEN22 ICEN24 ICEN32 ICEN33 ICEN35 ICEN36 ICEN37 ICEN39 ICEN7 IFI5111 INCENP ITGB3BP KIAA0044 KIAA0072 KIAA0077 KIAA0078 KIAA0097 KIAA0107 KIAA0165 KIAA0166 KIAA0178 KIAA0197 KIAA0261 KIAA0325 KIAA0622 KIAA0627 KIAA0648 KIAA0979 KIAA1361 KIAA1406 KIAA1470 KIAA1570 KIAA1835 KIF18A KIF2 KIF2A KIF2B KIF2C KLIP1 KNL1 KNS2 KNSL6 KNTC1 KNTC2 LIC2 LIS1 LMP10 LMP2 LMP7 LMPX LMPY LRPR1 MAD1 MAD1L1 MAD2 MAD2L1 MAD3L MAP3K16 MAPRE1 MARKK MAST1 MB1 MCB1 MCM21R MDCR MDS MECL1 MHF1 MIP224 MIS12 MIS13 MITAP1 MKSR2 MLF1IP MOV34L MPS1 MSS1 NDC80 NDE1 NDEL1 NRIF3 NSL1 NU NUDC NUDE NUDEL NUF2 NUF2R NUP107 NUP120 NUP133 NUP160 NUP358 NUP37 NUP43 NUP75 NUP85 NXP1 PAFAH1B1 PAFAHA PANE1 PBIP1 PCNT1 PDS5 PDS5A PDS5B PESCRG3 PFAAP4 PICH PLK PLK1 PMF1 POH1 PPP1CC PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 PTTG PTTG1 RAD21 RANBP2 RANGAP1 RCC2 RING10 RING12 RPS27 RPS27A RSN SA1 SA2 SB1.8 SCC1 SCC3 SD SEC13 SEC13A SEC13L1 SEC13R SEM1 SFT SGO1 SGO2 SGOL1 SGOL2 SHFDG1 SHFM1 SKA1 SKA2 SMC1 SMC1A SMC1L1 SMC3 SMC3L1 SPBC24 SPBC25 SPC24 SPC25 SPDL1 SSK1 STAG1 STAG2 STK1 STK12 STK5 SUG1 SUG2 TAOK1 TBP1 TBP7 TD60 TMBS62 TRAP2 TSG24 TUTR1 TXBP181 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S WAPAL WAPL X XPO1 Y Y2 Z ZW10 ZWILCH ZWINT	Homo sapiens (human)
Heme degradation	ATP-binding cassette sub-family C member 2 Albumin Beta-glucuronidase Biliverdin reductase A Broad substrate specificity ATP-binding cassette transporter ABCG2 Fatty acid-binding protein, liver Flavin reductase (NADPH) Glutathione S-transferase A1 Heme oxygenase 1 Heme oxygenase 2 Multidrug resistance-associated protein 1 Solute carrier organic anion transporter family member 1B1 Solute carrier organic anion transporter family member 1B3 UDP-glucuronosyltransferase 1A1 UDP-glucuronosyltransferase 1A4	P02768 P07148 P08263 P09601 P22309 P22310 P30043 P30519 P33527 P53004 Q8VNV4 Q92887 Q9NPD5 Q9UNQ0 Q9Y6L6	ABCC1 ABCC2 ABCG2 ABCP ALB BCRP BCRP1 BLVR BLVRA BLVRB BVR CMOAT CMOAT1 CMRP FABP1 FABPL FLR GNT1 GSTA1 HMOX1 HMOX2 HO HO1 HO2 LST1 LST2 MRP MRP1 MRP2 MXR OATP1B1 OATP1B3 OATP2 OATP8 OATPC SCAN SLC21A6 SLC21A8 SLCO1B1 SLCO1B3 UGT1 UGT1A1 UGT1A4	Homo sapiens (human)
APC/C:Cdc20 mediated degradation of mitotic proteins	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Mitotic checkpoint protein BUB3 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Mitotic spindle assembly checkpoint protein MAD2A Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S	O00762 O43684 O60566 P30260 P51668 P51965 P60006 Q12834 Q13042 Q13257 Q16763 Q8NHZ8 Q96DE5 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM13	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 BUB1B BUB3 BUBR1 C10orf104 C11orf51 C9orf17 CDC16 CDC20 CDC23 CDC26 CDC27 CENP-27 D0S1430E D17S978E E2EPF KIAA1406 MAD2 MAD2L1 MAD3L SFT SSK1 TSG24 UBC5A UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S	Homo sapiens (human)
Organic anion transport	Organic anion transporter 3 Solute carrier family 22 member 11 Solute carrier family 22 member 12 Solute carrier family 22 member 6 Solute carrier family 22 member 7	Q4U2R8 Q8TCC7 Q96S37 Q9NSA0 Q9Y694	NLT OAT1 OAT2 OAT3 OAT4 OATL4 PAHT SLC22A11 SLC22A12 SLC22A6 SLC22A7 SLC22A8 URAT1	Homo sapiens (human)
NR1D1 (REV-ERBA) represses gene expression	Histone deacetylase 3 Nuclear receptor corepressor 1 Nuclear receptor subfamily 1 group D member 1	O15379 O75376 P20393	EAR1 HDAC3 HREV KIAA1047 NCOR1 NR1D1 THRAL	Homo sapiens (human)
FLT3 signaling by CBL mutants	E3 ubiquitin-protein ligase CBL Fms-related tyrosine kinase 3 ligand Polyubiquitin-B Polyubiquitin-C Receptor-type tyrosine-protein kinase FLT3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P0CG47 P0CG48 P22681 P36888 P49771 P62979 P62987	CBL CBL2 CD135 FLK2 FLT3 FLT3LG RNF55 RPS27A STK1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Energy dependent regulation of mTOR by LKB1-AMPK	5'-AMP-activated protein kinase catalytic subunit alpha-1 5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-1 5'-AMP-activated protein kinase subunit gamma-2 5'-AMP-activated protein kinase subunit gamma-3 Calcium-binding protein 39-like Calcium-binding protein 39 GTP-binding protein Rheb Hamartin Neutral amino acid transporter 9 Protein phosphatase 1A Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein A Ras-related GTP-binding protein B Ras-related GTP-binding protein C Ras-related GTP-binding protein D Regulatory-associated protein of mTOR STE20-related kinase adapter protein alpha STE20-related kinase adapter protein beta Serine/threonine-protein kinase STK11 Serine/threonine-protein kinase mTOR Target of rapamycin complex subunit LST8 Tuberin	O43504 O43741 P35813 P42345 P49815 P54619 P54646 Q0VGL1 Q13131 Q15382 Q15831 Q5VZM2 Q6IAA8 Q7L523 Q7RTN6 Q8N122 Q8NBW4 Q92574 Q9BVC4 Q9C0K7 Q9H9S4 Q9HB90 Q9NQL2 Q9UGI9 Q9UGJ0 Q9UHA4 Q9Y2Q5 Q9Y376 Q9Y478	ALS2CR2 AMPK AMPK1 AMPK2 AMPKG3 C11orf59 C7orf59 CAB39 CAB39L FRAP FRAP1 FRAP2 GBL HBXIP ILPIP KIAA0243 KIAA1303 LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 LKB1 LST8 LYK5 MAP2K1IP1 MAPBPIP MAPKSP1 MLST8 MO25 MTOR PDRO PJS PPM1A PPPM1A PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 RAFT1 RAPT1 RAPTOR RHEB RHEB2 ROBLD3 RPTOR RRAGA RRAGB RRAGC RRAGD SLC38A9 STK11 STRAD STRADA STRADB TSC TSC1 TSC2 TSC4 URLC11 XIP	Homo sapiens (human)
Pyroptosis	Apoptosis regulator BAX Bcl-2 homologous antagonist/killer Caspase-1 Caspase-3 Caspase-4 Caspase-5 Cellular tumor antigen p53 Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4a Charged multivesicular body protein 4b Charged multivesicular body protein 4c Charged multivesicular body protein 6 Charged multivesicular body protein 7 Cytochrome c Gasdermin-D Gasdermin-E Granzyme B High mobility group protein B1 Interferon regulatory factor 1 Interferon regulatory factor 2 Interleukin-1 alpha Interleukin-1 beta Interleukin-18 Neutrophil elastase Tumor protein 63	O43633 O60443 P01583 P01584 P04637 P08246 P09429 P10144 P10914 P14316 P29466 P42574 P49662 P51878 P57764 P99999 Q07812 Q14116 Q16611 Q8WUX9 Q96CF2 Q96FZ7 Q9BY43 Q9H3D4 Q9H444 Q9UQN3 Q9Y3E7	BAK BAK1 BAX BC2 BCL2L4 BCL2L7 C14orf123 C20orf178 CASP1 CASP3 CASP4 CASP5 CDN1 CGI149 CGL1 CHMP2 CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP6 CHMP7 CPP32 CSPB CTLA1 CYC CYCS DFNA5 DFNA5L ELA2 ELANE GRB GSDMD GSDMDC1 GSDME GZMB HMG1 HMGB1 ICERE1 ICH2 ICH3 IGIF IL18 IL1A IL1B IL1BC IL1BCE IL1F1 IL1F2 IL1F4 IRF1 IRF2 KET NEDF P53 P63 P73H P73L SHAX1 SHAX2 SHAX3 TP53 TP63 TP73L VPS20 VPS24	Homo sapiens (human)
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members	Apoptosis regulator Bcl-2 BH3-interacting domain death agonist Bcl-2-binding component 3, isoforms 1/2 Bcl-2-like protein 11 Bcl-2-like protein 1 Bcl-2-modifying factor Bcl2-associated agonist of cell death Phorbol-12-myristate-13-acetate-induced protein 1 Signal transducer and activator of transcription 3	O43521 P10415 P40763 P55957 Q07817 Q13794 Q92934 Q96LC9 Q9BXH1	APRF BAD BBC3 BBC6 BCL2 BCL2L BCL2L1 BCL2L11 BCL2L8 BCLX BID BIM BMF NOXA PMAIP1 PUMA STAT3	Homo sapiens (human)
PRPP biosynthesis	Ribose-phosphate pyrophosphokinase 1 Ribose-phosphate pyrophosphokinase 2 Ribose-phosphate pyrophosphokinase 3	P11908 P21108 P60891	PRPS1 PRPS1L1 PRPS2 PRPS3 PRPSL	Homo sapiens (human)
Signaling by MAP2K mutants	Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3	P27361 P28482 P36507 Q02750	ERK1 ERK2 MAP2K1 MAP2K2 MAPK1 MAPK3 MEK1 MEK2 MKK2 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2	Homo sapiens (human)
GRB7 events in ERBB2 signaling	Growth factor receptor-bound protein 7 Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Receptor tyrosine-protein kinase erbB-2	O14511 P04626 Q02297 Q14451	ERBB2 GGF GRB7 HER2 HGL HRGA MLN19 NDF NEU NGL NRG1 NRG2 NTAK SMDF	Homo sapiens (human)
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	15-hydroxyprostaglandin dehydrogenase [NAD(+)] 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase Aldo-keto reductase family 1 member C3 Carbonyl reductase [NADPH] 1 Hematopoietic prostaglandin D synthase Prostacyclin synthase Prostaglandin E synthase 2 Prostaglandin E synthase 3 Prostaglandin E synthase Prostaglandin G/H synthase 1 Prostaglandin G/H synthase 2 Prostaglandin reductase 2 Prostaglandin-H2 D-isomerase Prostamide/prostaglandin F synthase Thromboxane-A synthase	O14684 O60760 P15428 P16152 P23219 P24557 P35354 P41222 P42330 Q15185 Q16647 Q8N8N7 Q8TBF2 Q9H7Z7 Q9UNU6	AKR1C3 C1orf93 C9orf15 CBR CBR1 COX1 COX2 CRN CYP12 CYP5 CYP5A1 CYP8 CYP8A1 CYP8B1 DDH1 FAM213B GSTS HPGD HPGDS HSD17B5 KIAA0119 MGST1L1 MPGES1 P23 PDS PGDH1 PGDS PGES PGES2 PGFS PIG12 PRXL2B PTGDS PTGDS2 PTGES PTGES2 PTGES3 PTGIS PTGR2 PTGS1 PTGS2 SDR21C1 SDR36C1 TBXAS1 TEBP TXAS ZADH1	Homo sapiens (human)
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB	Amine oxidase [flavin-containing] A Amine oxidase [flavin-containing] B	P21397 P27338	MAOA MAOB	Homo sapiens (human)
FGFR4 mutant receptor activation	Fibroblast growth factor receptor 4	P22455	FGFR4 JTK2 TKF	Homo sapiens (human)
Initiation of Nuclear Envelope (NE) Reformation	Ankyrin repeat and LEM domain-containing protein 2 Barrier-to-autointegration factor Cyclin-dependent kinase 1 Delta(14)-sterol reductase LBR Emerin G2/mitotic-specific cyclin-B1 G2/mitotic-specific cyclin-B2 Importin subunit beta-1 Inner nuclear membrane protein Man1 LEM domain-containing protein 2 Lamin-B1 NAD-dependent protein deacetylase sirtuin-2 Serine/threonine-protein kinase VRK1 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	O75531 O95067 P06493 P14635 P20700 P30153 P50402 P63151 P67775 Q14739 Q14974 Q86XL3 Q8IXJ6 Q8NC56 Q99986 Q9Y2U8	ANKLE2 BAF BANF1 BCRG1 CCNB CCNB1 CCNB2 CDC2 CDC28A CDK1 CDKN1 EDMD EMD KIAA0692 KPNB1 LBR LEM4 LEMD2 LEMD3 LMN2 LMNB LMNB1 MAN1 NTF97 P34CDC2 PPP2CA PPP2R1A PPP2R2A SIR2L SIR2L2 SIRT2 STA VRK1	Homo sapiens (human)
Vitamin B1 (thiamin) metabolism	Mitochondrial thiamine pyrophosphate carrier Thiamin pyrophosphokinase 1 Thiamine transporter 1 Thiamine transporter 2 Thiamine-triphosphatase	O60779 Q9BU02 Q9BZV2 Q9H3S4 Q9HC21	DNC MUP1 SLC19A2 SLC19A3 SLC25A19 THT1 THTPA TPK1 TRMA	Homo sapiens (human)
Abacavir transmembrane transport	ATP-dependent translocase ABCB1 Broad substrate specificity ATP-binding cassette transporter ABCG2 Solute carrier family 22 member 1 Solute carrier family 22 member 2 Solute carrier family 22 member 3	O15244 O15245 O75751 P08183 Q9UNQ0	ABCB1 ABCG2 ABCP BCRP BCRP1 EMTH MDR1 MXR OCT1 OCT2 OCT3 PGY1 SLC22A1 SLC22A2 SLC22A3	Homo sapiens (human)
Ca2+ pathway	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 Calcineurin subunit B type 1 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calmodulin-1 Catenin beta-1 Frizzled-2 Frizzled-3 Frizzled-4 Frizzled-5 Frizzled-6 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(o) subunit alpha Guanine nucleotide-binding protein G(t) subunit alpha-2 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Helicase MOV-10 Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Lymphoid enhancer-binding factor 1 Mitogen-activated protein kinase kinase kinase 7 Nuclear factor of activated T-cells, cytoplasmic 1 Protein Wnt-11 Protein Wnt-5a Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Protein kinase C alpha type Protein phosphatase 3 catalytic subunit alpha Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta Serine/threonine-protein kinase NLK Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform Transcription factor 7-like 1 Transcription factor 7-like 2 Transcription factor 7 Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein cGMP-dependent protein kinase 1 cGMP-dependent protein kinase 2	O14610 O14775 O43318 O60262 O60353 O95644 O96014 P09471 P0DP23 P16298 P16499 P16520 P17252 P18545 P19087 P35222 P35913 P36402 P41221 P50150 P50151 P59768 P61952 P62873 P62879 P63098 P63211 P63215 P63218 Q00722 Q01970 Q08209 Q13237 Q13467 Q13976 Q14332 Q14571 Q14573 Q14643 Q8NDV7 Q9H9G7 Q9HAV0 Q9HCE1 Q9HCJ0 Q9HCK5 Q9HCS4 Q9NPG1 Q9NQ66 Q9NQB0 Q9P2W3 Q9UBE8 Q9UBI6 Q9UJU2 Q9UK08 Q9UKV8 Q9UL18 Q9ULV1 Q9UPQ9 Q9UQM7	AGO1 AGO2 AGO3 AGO4 C2orf31 CAGH26 CALM CALM1 CALNA CALNA2 CALNB CAM CAM1 CAMK2A CAMKA CNA CNA2 CNB CTNNB CTNNB1 EIF2C1 EIF2C2 EIF2C3 EIF2C4 FZD2 FZD3 FZD4 FZD5 FZD6 GNAO1 GNAT2 GNATC GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 INSP3R1 ITPR1 ITPR2 ITPR3 KIAA0581 KIAA0968 KIAA1093 KIAA1460 KIAA1567 KIAA1582 KIAA1631 LAK1 LEF1 MAP3K7 MOV10 NFAT2 NFATC NFATC1 NLK PDE6A PDE6B PDE6G PDEA PDEB PDEG PKCA PLCB1 PLCB2 PLCB3 PPP3CA PPP3CB PPP3R1 PRKACA PRKCA PRKG1 PRKG1B PRKG2 PRKGR1A PRKGR1B PRKGR2 TAK1 TCF1 TCF3 TCF4 TCF7 TCF7L1 TCF7L2 TNRC6 TNRC6A TNRC6B TNRC6C WNT11 WNT5A	Homo sapiens (human)
Removal of aminoterminal propeptides from gamma-carboxylated proteins	Coagulation factor IX Coagulation factor VII Coagulation factor X Furin Growth arrest-specific protein 6 Osteocalcin Prothrombin Vitamin K-dependent protein C Vitamin K-dependent protein S Vitamin K-dependent protein Z	P00734 P00740 P00742 P02818 P04070 P07225 P08709 P09958 P22891 Q14393	AXLLG BGLAP F10 F2 F7 F9 FUR FURIN GAS6 PACE PCSK3 PROC PROS PROS1 PROZ	Homo sapiens (human)
Transport of inorganic cations/anions and amino acids/oligopeptides	Cystinosin Excitatory amino acid transporter 1 Excitatory amino acid transporter 2 Excitatory amino acid transporter 3 Excitatory amino acid transporter 4 Excitatory amino acid transporter 5 Mitochondrial S-adenosylmethionine carrier protein Vesicular inhibitory amino acid transporter	O00341 O60931 P43003 P43004 P43005 P48664 Q70HW3 Q9H598	CTNS EAAC1 EAAT1 EAAT2 EAAT3 EAAT4 EAAT5 GLAST GLAST1 GLT1 HEAAC1 SAMC SLC1A1 SLC1A2 SLC1A3 SLC1A6 SLC1A7 SLC25A26 SLC32A1 VGAT VIAAT	Homo sapiens (human)
Defective SLC6A18 may confer susceptibility to iminoglycinuria and/or hyperglycinuria	Inactive sodium-dependent neutral amino acid transporter B(0)AT3	Q96N87	B0AT3 SLC6A18 XTRP2	Homo sapiens (human)
Sunitinib-resistant PDGFR mutants	Platelet-derived growth factor receptor alpha	P16234	PDGFR2 PDGFRA RHEPDGFRA	Homo sapiens (human)
Regulation of TP53 Expression	Cellular tumor antigen p53 PR domain zinc finger protein 1	O75626 P04637	BLIMP1 P53 PRDM1 TP53	Homo sapiens (human)
Defective SLC24A1 causes congenital stationary night blindness 1D (CSNB1D)	Sodium/potassium/calcium exchanger 1	O60721	KIAA0702 NCKX1 SLC24A1	Homo sapiens (human)

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