GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **501 - 525** of **2090** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism
Transcriptional Regulation by VENTX	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 CCAAT/enhancer-binding protein beta Catenin beta-1 Cell division cycle protein 16 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Cellular tumor antigen p53 Cyclin-dependent kinase inhibitor 2A Fizzy-related protein homolog G1/S-specific cyclin-D1 Helicase MOV-10 Histone-lysine N-methyltransferase EHMT1 Histone-lysine N-methyltransferase EHMT2 Homeobox protein VENTX Interleukin-6 Lymphoid enhancer-binding factor 1 Macrophage colony-stimulating factor 1 receptor Nuclear factor NF-kappa-B p105 subunit Protein argonaute-1 Protein argonaute-3 Protein argonaute-4 Transcription factor 7-like 2 Transcription factor p65 Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S	O00762 O95231 P04637 P05231 P07333 P17676 P19838 P24385 P30260 P35222 P42771 P51668 P51965 P60006 Q04206 Q13042 Q16763 Q8NDV7 Q8NHZ8 Q96DE5 Q96KQ7 Q9H1A4 Q9H9B1 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9NQB0 Q9NYG5 Q9UJU2 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UL18 Q9UM11 Q9UM13 Q9UPQ9	AGO1 AGO3 AGO4 ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 BAT8 BCL1 C10orf104 C11orf51 C6orf30 C9orf17 CAGH26 CCND1 CDC16 CDC23 CDC26 CDC27 CDH1 CDKN2 CDKN2A CEBPB CENP-27 CSF1R CTNNB CTNNB1 D0S1430E D17S978E E2EPF EHMT1 EHMT2 EIF2C1 EIF2C3 EIF2C4 EUHMTASE1 FMS FYR FZR FZR1 G9A GLP HPX42B IFNB2 IL6 KIAA1093 KIAA1242 KIAA1406 KIAA1460 KIAA1567 KIAA1582 KIAA1631 KIAA1876 KMT1C KMT1D LEF1 MOV10 MTS1 NFKB1 NFKB3 NG36 P53 PRAD1 RELA SFT TCF4 TCF5 TCF7L2 TNRC6 TNRC6A TNRC6B TNRC6C TP53 TSG24 UBC5A UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S VENTX VENTX2	Homo sapiens (human)
Aberrant regulation of mitotic exit in cancer due to RB1 defects	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Fizzy-related protein homolog Retinoblastoma-associated protein S-phase kinase-associated protein 2 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S	O00762 P06400 P30260 P51668 P51965 P60006 Q13042 Q13309 Q16763 Q8NHZ8 Q96DE5 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM11 Q9UM13	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 C10orf104 C11orf51 C9orf17 CDC16 CDC23 CDC26 CDC27 CDH1 CENP-27 D0S1430E D17S978E E2EPF FBXL1 FYR FZR FZR1 KIAA1242 KIAA1406 RB1 SFT SKP2 TSG24 UBC5A UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S	Homo sapiens (human)
APC/C:Cdc20 mediated degradation of Cyclin B	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 Polyubiquitin-B Polyubiquitin-C Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00762 P06493 P0CG47 P0CG48 P14635 P30260 P51668 P51965 P60006 P62979 P62987 Q12834 Q13042 Q16763 Q8NHZ8 Q96DE5 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM13	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 C10orf104 C11orf51 C9orf17 CCNB CCNB1 CDC16 CDC2 CDC20 CDC23 CDC26 CDC27 CDC28A CDK1 CDKN1 CENP-27 D0S1430E D17S978E E2EPF KIAA1406 P34CDC2 RPS27A SFT TSG24 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S	Homo sapiens (human)
Regulation of APC/C activators between G1/S and early anaphase	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 1 Cyclin-dependent kinase 2 F-box only protein 5 Fizzy-related protein homolog G2/mitotic-specific cyclin-B1 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S	O00762 P06493 P14635 P20248 P24941 P30260 P51668 P51965 P60006 P78396 Q12834 Q13042 Q16763 Q8NHZ8 Q96DE5 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UKT4 Q9UM11 Q9UM13	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 C10orf104 C11orf51 C9orf17 CCN1 CCNA CCNA1 CCNA2 CCNB CCNB1 CDC16 CDC2 CDC20 CDC23 CDC26 CDC27 CDC28A CDH1 CDK1 CDK2 CDKN1 CDKN2 CENP-27 D0S1430E D17S978E E2EPF EMI1 FBX5 FBXO5 FYR FZR FZR1 KIAA1242 KIAA1406 P34CDC2 SFT TSG24 UBC5A UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S	Homo sapiens (human)
Phosphorylation of the APC/C	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 Serine/threonine-protein kinase PLK1 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S	O00762 P06493 P14635 P30260 P51668 P51965 P53350 P60006 Q13042 Q16763 Q8NHZ8 Q96DE5 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM13	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 C10orf104 C11orf51 C9orf17 CCNB CCNB1 CDC16 CDC2 CDC23 CDC26 CDC27 CDC28A CDK1 CDKN1 CENP-27 D0S1430E D17S978E E2EPF KIAA1406 P34CDC2 PLK PLK1 SFT TSG24 UBC5A UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S	Homo sapiens (human)
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Dual specificity protein phosphatase CDC14A Fizzy-related protein homolog Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S	O00762 P30260 P51668 P51965 P60006 Q12834 Q13042 Q16763 Q8NHZ8 Q96DE5 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM11 Q9UM13 Q9UNH5	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 C10orf104 C11orf51 C9orf17 CDC14A CDC16 CDC20 CDC23 CDC26 CDC27 CDH1 CENP-27 D0S1430E D17S978E E2EPF FYR FZR FZR1 KIAA1242 KIAA1406 SFT TSG24 UBC5A UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S	Homo sapiens (human)
Activation of gene expression by SREBF (SREBP)	3'-5' exoribonuclease HELZ2 7-dehydrocholesterol reductase Acetyl-CoA carboxylase 1 Acetyl-CoA carboxylase 2 CREB-binding protein Chromodomain-helicase-DNA-binding protein 9 Delta(14)-sterol reductase TM7SF2 Diphosphomevalonate decarboxylase F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Farnesyl pyrophosphate synthase Fatty acid synthase Geranylgeranyl pyrophosphate synthase Glycerol-3-phosphate acyltransferase 1, mitochondrial Histone-arginine methyltransferase CARM1 Hydroxymethylglutaryl-CoA synthase, cytoplasmic Isopentenyl-diphosphate Delta-isomerase 1 Lanosterol 14-alpha demethylase Lanosterol synthase Lathosterol oxidase Mediator of RNA polymerase II transcription subunit 1 Metal regulatory transcription factor 1 Mevalonate kinase Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Nuclear receptor coactivator 6 Nuclear transcription factor Y subunit alpha Nuclear transcription factor Y subunit beta Nuclear transcription factor Y subunit gamma Peroxisome proliferator-activated receptor alpha Phosphomevalonate kinase Retinoic acid receptor RXR-alpha SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 Squalene monooxygenase Squalene synthase Stearoyl-CoA desaturase Sterol regulatory element-binding protein 2 Transcription factor Sp1 Trimethylguanosine synthase Very long chain fatty acid elongase 6	O00763 O00767 O60907 O75845 O76062 O95749 P08047 P14324 P19793 P23511 P25208 P37268 P48449 P49327 P53602 Q01581 Q03426 Q07869 Q12772 Q13085 Q13907 Q13952 Q14534 Q14686 Q14872 Q15126 Q15596 Q15648 Q15788 Q16850 Q3L8U1 Q6STE5 Q86X55 Q92793 Q96RS0 Q9BYK8 Q9BZK7 Q9H5J4 Q9HCL2 Q9UBM7	ACAC ACACA ACACB ACC1 ACC2 ACCA ACCB AIB3 ANG1 ARC205 BAF60C BHLHD2 BHLHE74 BHLHE75 CARM1 CBP CHD9 CREBBP CRSP1 CRSP200 CYP51 CYP51A1 D7SR DHCR7 DRIP205 DRIP230 ELOVL6 ERG1 FACE FADS5 FAS FASN FDFT1 FDPS FPS GGPS1 GPAM GPAT1 HAP3 HCA137 HELZ2 HMGCS HMGCS1 IDI1 IRA1 KIAA0181 KIAA0308 KIAA1293 KIAA1560 KIAA1769 KISH2 LCE LSS MED1 MPD MTF1 MVD MVK NCOA1 NCOA2 NCOA6 NCOA6IP NFYA NFYB NFYC NR1C1 NR2B1 OSC PBP PIMT PMKI PMVK PPAR PPARA PPARBP PPARGBP PRIC285 PRIC320 PRMT4 RAP250 RB18A RXRA SC5D SC5DL SCD SCD1 SCDOS SMARCD3 SP1 SQLE SRC1 SRC2 SREBF2 SREBP2 TBL1 TBL1X TBL1XR1 TBLR1 TGS1 TIF2 TM7SF2 TRAP220 TRBP TRIP2 TSFP1	Homo sapiens (human)
Biotin transport and metabolism	Acetyl-CoA carboxylase 1 Acetyl-CoA carboxylase 2 Biotin--protein ligase Biotinidase Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial PDZ domain-containing protein 11 Propionyl-CoA carboxylase alpha chain, mitochondrial Propionyl-CoA carboxylase beta chain, mitochondrial Pyruvate carboxylase, mitochondrial Sodium-dependent multivitamin transporter	O00763 P05165 P05166 P11498 P43251 P50747 Q13085 Q5EBL8 Q96RQ3 Q9HCC0 Q9Y289	ACAC ACACA ACACB ACC1 ACC2 ACCA ACCB AIPP1 BTD HLCS MCCA MCCB MCCC1 MCCC2 PC PCCA PCCB PDZD11 PDZK11 PISP SLC5A6 SMVT	Homo sapiens (human)
ChREBP activates metabolic gene expression	1-acyl-sn-glycerol-3-phosphate acyltransferase alpha ATP-citrate synthase Acetyl-CoA carboxylase 1 Acetyl-CoA carboxylase 2 Carbohydrate-responsive element-binding protein Fatty acid synthase Max-like protein X	O00763 P49327 P53396 Q13085 Q99943 Q9NP71 Q9UH92	ACAC ACACA ACACB ACC1 ACC2 ACCA ACCB ACLY AGPAT1 BHLHD13 BHLHD14 FAS FASN G15 MIO MLX MLXIPL TCFL4 WBSCR14	Homo sapiens (human)
Vitamin B6 activation to pyridoxal phosphate	Aldehyde oxidase Pyridoxal kinase Pyridoxine-5'-phosphate oxidase	O00764 Q06278 Q9NVS9	AO AOX1 C21orf124 C21orf97 PDXK PKH PNK PNPO	Homo sapiens (human)
Fatty acyl-CoA biosynthesis	(3R)-3-hydroxyacyl-CoA dehydrogenase 3-oxoacyl-[acyl-carrier-protein] reductase ATP-citrate synthase ATPase MORC2 Acetyl-CoA carboxylase 1 Fatty acid synthase Hydroxyacyl-thioester dehydratase type 2, mitochondrial Long-chain fatty acid transport protein 2 Lysosomal thioesterase PPT2 Palmitoyl-protein thioesterase 1 S-acyl fatty acid synthase thioesterase, medium chain Stearoyl-CoA desaturase 5 Stearoyl-CoA desaturase	O00767 O14975 P49327 P50897 P53396 P86397 Q13085 Q86SK9 Q8N4T8 Q92506 Q9NV23 Q9UMR5 Q9Y6X9	ACAC ACACA ACC1 ACCA ACLY ACOD4 ACSVL1 CBR4 CLN1 FABGL FACVL1 FADS5 FAS FASN FATP2 HKE6 HSD17B8 HTD2 KIAA0852 MORC2 OLAH PPT PPT1 PPT2 RING2 SCD SCD1 SCD2 SCD4 SCD5 SCDOS SDR30C1 SDR45C1 SLC27A2 THEDC1 VLACS ZCWCC1	Homo sapiens (human)
LXRs regulate gene expression linked to lipogenesis	Angiopoietin-related protein 3 Fatty acid synthase Nuclear receptor-interacting protein 1 Oxysterols receptor LXR-alpha Oxysterols receptor LXR-beta Retinoic acid receptor RXR-alpha Retinoic acid receptor RXR-beta Stearoyl-CoA desaturase	O00767 P19793 P28702 P48552 P49327 P55055 Q13133 Q9Y5C1	ANGPT5 ANGPTL3 FADS5 FAS FASN LXRA LXRB NER NR1H2 NR1H3 NR2B1 NR2B2 NRIP1 RXRA RXRB SCD SCD1 SCDOS UNR	Homo sapiens (human)
Neurexins and neuroligins	Amyloid-beta A4 precursor protein-binding family A member 1 Amyloid-beta A4 precursor protein-binding family A member 2 Amyloid-beta A4 precursor protein-binding family A member 3 Band 4.1-like protein 1 Band 4.1-like protein 2 Band 4.1-like protein 3 Band 4.1-like protein 5 Brain-enriched guanylate kinase-associated protein Disks large homolog 2 Disks large homolog 3 Disks large homolog 4 Disks large-associated protein 1 Disks large-associated protein 2 Disks large-associated protein 3 Disks large-associated protein 4 Drebrin-like protein Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2A Glutamate receptor ionotropic, NMDA 2B Glutamate receptor ionotropic, NMDA 2C Glutamate receptor ionotropic, NMDA 2D Homer protein homolog 1 Homer protein homolog 2 Homer protein homolog 3 Leucine-rich repeat transmembrane neuronal protein 1 Leucine-rich repeat transmembrane neuronal protein 2 Leucine-rich repeat transmembrane neuronal protein 3 Leucine-rich repeat transmembrane neuronal protein 4 Metabotropic glutamate receptor 1 Metabotropic glutamate receptor 5 Neurexin-1-beta Neurexin-1 Neurexin-2-beta Neurexin-2 Neurexin-3-beta Neurexin-3 Neuroligin-1 Neuroligin-2 Neuroligin-3 Neuroligin-4, X-linked Neuroligin-4, Y-linked PDZ and LIM domain protein 5 Peripheral plasma membrane protein CASK Protein 4.1 Protein lin-7 homolog A Protein lin-7 homolog B Protein lin-7 homolog C SH3 and multiple ankyrin repeat domains protein 1 SH3 and multiple ankyrin repeat domains protein 2 SH3 and multiple ankyrin repeat domains protein 3 Sharpin Signal-induced proliferation-associated 1-like protein 1 Synaptotagmin-10 Synaptotagmin-12 Synaptotagmin-1 Synaptotagmin-2 Synaptotagmin-7 Synaptotagmin-9 Syntaxin-1A Syntaxin-binding protein 1	O14490 O14910 O14936 O15399 O43166 O43300 O43491 O43581 O95886 O96018 P11171 P21579 P41594 P58400 P58401 P61764 P78352 Q02410 Q05586 Q12879 Q13224 Q13255 Q14957 Q15700 Q16623 Q6XYQ8 Q86SS6 Q86UE6 Q86VH4 Q86VH5 Q86YM7 Q8IV01 Q8N0W4 Q8N2Q7 Q8N9I0 Q8NFZ3 Q8NFZ4 Q92796 Q96HC4 Q99767 Q9BUH8 Q9BYB0 Q9H0F6 Q9H4G0 Q9HAP6 Q9HCM4 Q9HDB5 Q9NSB8 Q9NSC5 Q9NUP9 Q9NZ94 Q9P1A6 Q9P2S2 Q9UJU6 Q9ULB1 Q9UPX8 Q9Y2H0 Q9Y2J2 Q9Y4C0 Q9Y566	APBA1 APBA2 APBA3 BEGAIN C14orf60 C8orf68 CASK CMAP CORTBP1 DAL1 DAP1 DAP2 DAP3 DAP4 DBNL DLG2 DLG3 DLG4 DLGAP1 DLGAP2 DLGAP3 DLGAP4 E41P E6TP1 ENH EPB41 EPB41L1 EPB41L2 EPB41L3 EPB41L5 ERICH1-AS1 GKAP GPRC1A GPRC1E GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D GRM1 GRM5 GluN2D HOMER1 HOMER2 HOMER3 KIAA0338 KIAA0416 KIAA0440 KIAA0578 KIAA0743 KIAA0921 KIAA0951 KIAA0964 KIAA0987 KIAA1022 KIAA1070 KIAA1232 KIAA1260 KIAA1366 KIAA1446 KIAA1480 KIAA1548 KIAA1650 LIN2 LIN7A LIN7B LIN7C LRRN2 LRRTM1 LRRTM2 LRRTM3 LRRTM4 MALS1 MALS2 MALS3 MGLUR1 MGLUR5 MINT1 MINT2 MINT3 NL3 NLGN1 NLGN2 NLGN3 NLGN4 NLGN4X NLGN4Y NMDAR1 NMDAR2A NMDAR2B NMDAR2C NMDAR2D NRXN1 NRXN2 NRXN3 PCANAP7 PDLIM5 PROSAP1 PROSAP2 PSAP2 PSD95 SAPAP4 SH3P7 SHANK1 SHANK2 SHANK3 SHARPIN SIPA1L1 SIPL1 STX1 STX1A STXBP1 SVP65 SYN47 SYT SYT1 SYT10 SYT12 SYT2 SYT7 SYT9 UNC18A VELI1 VELI2 VELI3 X11 X11L X11L2	Homo sapiens (human)
Regulation of KIT signaling	E3 ubiquitin-protein ligase CBL Mast/stem cell growth factor receptor Kit Protein kinase C alpha type SH2B adapter protein 2 SH2B adapter protein 3 Son of sevenless homolog 1 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 6 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lck Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes Tyrosine-protein phosphatase non-receptor type 6	O14492 O14544 O15524 P06239 P06241 P07947 P07948 P10721 P17252 P22681 P29350 Q07889 Q9UQQ2	APS CBL CBL2 CIS4 FYN HCP JTK8 KIT LCK LNK LYN PKCA PRKACA PRKCA PTP1C PTPN6 RNF55 SCFR SH2B2 SH2B3 SOCS1 SOCS4 SOCS6 SOS1 SSI1 TIP3 YES YES1	Homo sapiens (human)
Factors involved in megakaryocyte development and platelet production	A-kinase anchor protein 1, mitochondrial A-kinase anchor protein 10, mitochondrial CDK5 and ABL1 enzyme substrate 1 CDK5 and ABL1 enzyme substrate 2 Cell division control protein 42 homolog Cellular tumor antigen p53 Chromobox protein homolog 5 Cyclin-dependent kinase 2 Cyclin-dependent kinase 5 DNA repair protein RAD51 homolog 2 DNA repair protein RAD51 homolog 3 Dedicator of cytokinesis protein 10 Dedicator of cytokinesis protein 11 Dedicator of cytokinesis protein 1 Dedicator of cytokinesis protein 2 Dedicator of cytokinesis protein 3 Dedicator of cytokinesis protein 4 Dedicator of cytokinesis protein 5 Dedicator of cytokinesis protein 6 Dedicator of cytokinesis protein 7 Dedicator of cytokinesis protein 8 Dedicator of cytokinesis protein 9 EH domain-containing protein 1 EH domain-containing protein 2 EH domain-containing protein 3 Endothelial transcription factor GATA-2 Erythroid transcription factor F-actin-capping protein subunit alpha-1 F-actin-capping protein subunit alpha-2 F-actin-capping protein subunit beta F-actin-uncapping protein LRRC16A GTP Hemoglobin subunit beta Hemoglobin subunit delta Hemoglobin subunit epsilon Hemoglobin subunit gamma-1 Hemoglobin subunit gamma-2 Histone H3.1 Histone H3.2 Histone H3.3 Histone deacetylase 1 Histone deacetylase 2 Inositol-tetrakisphosphate 1-kinase Interferon alpha-1/13 Interferon alpha-10 Interferon alpha-14 Interferon alpha-16 Interferon alpha-17 Interferon alpha-21 Interferon alpha-2 Interferon alpha-4 Interferon alpha-5 Interferon alpha-6 Interferon alpha-7 Interferon alpha-8 Interferon beta Interferon regulatory factor 1 Interferon regulatory factor 2 Lysine-specific histone demethylase 1A Mitofusin-1 Mitofusin-2 PHD finger protein 21A Paired amphipathic helix protein Sin3a Probable JmjC domain-containing histone demethylation protein 2C REST corepressor 1 Rabenosyn-5 Ras-related C3 botulinum toxin substrate 1 Ras-related protein Rab-5A SH2B adapter protein 1 SH2B adapter protein 2 SH2B adapter protein 3 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related Trans-acting T-cell-specific transcription factor GATA-3 Transcription factor GATA-4 Transcription factor GATA-5 Transcription factor GATA-6 Transcription factor MafF Transcription factor MafG Transcription factor MafK Transcription factor NF-E2 45 kDa subunit Transcriptional activator Myb Tyrosine-protein kinase ABL1 Tyrosine-protein kinase JAK2 Vacuolar protein sorting-associated protein 45 Wee1-like protein kinase Zinc finger protein ZFPM1 Zinc finger protein ZFPM2 [F-actin]-monooxygenase MICAL1 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	O14492 O15315 O15525 O43502 O43572 O60341 O60674 O60675 O95140 P00519 P01562 P01563 P01566 P01567 P01568 P01569 P01570 P01571 P01574 P02042 P02100 P04637 P05013 P05014 P05015 P10242 P10644 P10914 P13861 P14316 P15976 P17612 P20339 P22612 P22694 P23769 P23771 P24941 P30291 P31321 P31323 P32881 P43694 P45973 P47755 P47756 P52907 P60953 P63000 P68431 P68871 P69891 P69892 P84243 Q00535 Q13547 Q13572 Q14185 Q15652 Q16621 Q5JSL3 Q5VZK9 Q71DI3 Q8IWA4 Q8IX07 Q8IZD9 Q8N1I0 Q8NF50 Q8TDN4 Q8TDZ2 Q8WW38 Q92608 Q92667 Q92769 Q92908 Q96BD5 Q96BY6 Q96HP0 Q96N67 Q96ST3 Q9BTV7 Q9BWX5 Q9BZ29 Q9H1K0 Q9H4M9 Q9H7D0 Q9NRF2 Q9NRW7 Q9NZN3 Q9NZN4 Q9P0W2 Q9UIJ7 Q9UKL0 Q9ULX9 Q9UQQ2	ABL ABL1 AK3 AK3L1 AK6 AKAP1 AKAP10 AKAP149 AKL3L AOF2 APS BHC80 BRAF35 C20orf150 CABLES CABLES1 CABLES2 CAPZA1 CAPZA2 CAPZB CARMIL CARMIL1 CBX5 CDC42 CDK2 CDK5 CDKN2 CDKN5 CPRP1 DOCK1 DOCK10 DOCK11 DOCK2 DOCK3 DOCK4 DOCK5 DOCK6 DOCK7 DOCK8 DOCK9 EHD1 EHD2 EHD3 ERYF1 FOG1 FOG2 GATA1 GATA2 GATA3 GATA4 GATA5 GATA6 GF1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM HBB HBD HBE HBE1 HBG1 HBG2 HDAC1 HDAC2 HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST2H3A HIST2H3C HIST2H3D HMG20B HMGX2 HMGXB2 HP1A IFB IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA2A IFNA2B IFNA2C IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNB IFNB1 IRF1 IRF2 ITPK1 JAK2 JHDM2C JMJD1C JTK7 KDM1 KDM1A KIAA0071 KIAA0209 KIAA0214 KIAA0299 KIAA0601 KIAA0694 KIAA0716 KIAA1058 KIAA1299 KIAA1380 KIAA1395 KIAA1696 KIAA1771 LNK LRRC16 LRRC16A LSD1 MAFF MAFG MAFK MFN1 MFN2 MICAL MICAL1 MOCA MYB NFE2 NICAL P53 PAST PAST1 PAST2 PAST3 PHF21A PKACA PKR1 PKR2 PRKA1 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B PSSALRE RAB5 RAB5A RAC1 RAD51B RAD51C RAD51L1 RAD51L2 RBSN RCOR RCOR1 REC2 RPD3L1 SH2B SH2B1 SH2B2 SH2B3 SIN3A SMARCE1R TC25 TP53 TRIP8 TSE1 VPS45 VPS45A VPS45B WEE1 ZFN89A ZFPM1 ZFPM2 ZFYVE20 ZIZ1 ZIZ2 ZIZ3 ZNF89B	Homo sapiens (human)
Sphingolipid catabolism	Aldehyde dehydrogenase family 3 member B1 Aldehyde dehydrogenase family 3 member B2 Alkaline ceramidase 1 Alkaline ceramidase 2 Alkaline ceramidase 3 Phospholipid phosphatase 1 Phospholipid phosphatase 2 Phospholipid phosphatase 3 Sphingosine-1-phosphate lyase 1 Sphingosine-1-phosphate phosphatase 1 Sphingosine-1-phosphate phosphatase 2	O14494 O14495 O43688 O95470 P43353 P48448 Q5QJU3 Q8IWX5 Q8TDN7 Q9BX95 Q9NUN7	ACER1 ACER2 ACER3 ALDH3B1 ALDH3B2 ALDH7 ALDH8 APHC ASAH3 ASAH3L KIAA1252 LPP1 LPP2 LPP3 PHCA PLPP1 PLPP2 PLPP3 PPAP2A PPAP2B PPAP2C SGPL1 SGPP1 SGPP2 SPP1	Homo sapiens (human)
RMTs methylate histone arginines	AT-rich interactive domain-containing protein 1A AT-rich interactive domain-containing protein 1B AT-rich interactive domain-containing protein 2 Actin-like protein 6A Actin-like protein 6B Coordinator of PRMT5 and differentiation stimulator Cyclin-dependent kinase 4 DNA (cytosine-5)-methyltransferase 3A G1/S-specific cyclin-D1 Histone H2A type 1-A Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-H Histone H2A type 1-J Histone H2A type 1 Histone H2A type 2-A Histone H2A type 2-B Histone H2A type 2-C Histone H2A type 3 Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H3.1 Histone H3.2 Histone H4 Histone-arginine methyltransferase CARM1 Histone-binding protein RBBP7 Methylosome protein WDR77 Probable global transcription activator SNF2L2 Protein arginine N-methyltransferase 1 Protein arginine N-methyltransferase 3 Protein arginine N-methyltransferase 5 Protein arginine N-methyltransferase 6 Protein arginine N-methyltransferase 7 Protein polybromo-1 SWI/SNF complex subunit SMARCC1 SWI/SNF complex subunit SMARCC2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 Small ribosomal subunit protein uS5 Transcription activator BRG1 Tyrosine-protein kinase JAK2 WD repeat-containing protein 5	O14497 O14744 O60674 O60678 O94805 O96019 P04908 P0C0S8 P0C5Y9 P11802 P15880 P16104 P20671 P24385 P51531 P51532 P61964 P62805 P68431 Q12824 Q16576 Q16777 Q68CP9 Q6FI13 Q6STE5 Q71DI3 Q71UI9 Q7L7L0 Q86U86 Q86X55 Q8IUE6 Q8NFD5 Q8TAQ2 Q92922 Q92925 Q93077 Q969G3 Q96GM5 Q96KK5 Q96LA8 Q96QV6 Q99873 Q99878 Q9BQA1 Q9BTM1 Q9NQ92 Q9NVM4 Q9Y6K1	ACTL6 ACTL6A ACTL6B ARID1A ARID1B ARID2 BAF155 BAF170 BAF180 BAF190A BAF190B BAF200 BAF250 BAF250A BAF250B BAF47 BAF53 BAF53A BAF53B BAF57 BAF60A BAF60B BAF60C BCL1 BIG3 BRG1 BRM C17orf79 C1orf4 CARM1 CCND1 CDK4 COPR5 COPRS DAN15 DNMT3A H2AB1 H2AC1 H2AC11 H2AC12 H2AC13 H2AC14 H2AC15 H2AC16 H2AC17 H2AC18 H2AC19 H2AC20 H2AC21 H2AC25 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFC H2AFD H2AFE H2AFG H2AFI H2AFJ H2AFL H2AFM H2AFN H2AFO H2AFP H2AFQ H2AFR H2AFV H2AFX H2AJ H2AV H2AW H2AX H2AZ2 H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIST1H2AA HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AG HIST1H2AH HIST1H2AI HIST1H2AJ HIST1H2AK HIST1H2AL HIST1H2AM HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AB HIST2H2AC HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2A HIST4H4 HMT2 HRMT1L2 HRMT1L3 HRMT1L5 HRMT1L6 IBP72 INI1 INO80K IR1B4 JAK2 JBP1 KIAA1235 KIAA1557 KIAA1933 MEP50 OSA1 OSA2 PB1 PBRM1 PRAD1 PRMT1 PRMT3 PRMT4 PRMT5 PRMT6 PRMT7 RBAP46 RBBP7 RPS2 RPS4 SKB1 SMARCA2 SMARCA4 SMARCB1 SMARCC1 SMARCC2 SMARCD1 SMARCD2 SMARCD3 SMARCE1 SMARCF1 SNF2A SNF2B SNF2L2 SNF2L4 SNF5L1 WD45 WDR5 WDR77	Homo sapiens (human)
Regulation of MITF-M-dependent genes involved in pigmentation	5,6-dihydroxyindole-2-carboxylic acid oxidase AT-rich interactive domain-containing protein 1A AT-rich interactive domain-containing protein 1B Actin, cytoplasmic 1 Actin-like protein 6A B-cell CLL/lymphoma 7 protein family member A B-cell CLL/lymphoma 7 protein family member B B-cell CLL/lymphoma 7 protein family member C Calcium-responsive transactivator Catenin beta-1 G-protein coupled receptor 143 L-dopachrome tautomerase Lymphoid enhancer-binding factor 1 Melanocyte protein PMEL Melanoma antigen recognized by T-cells 1 Probable global transcription activator SNF2L2 Protein SSXT RAC-beta serine/threonine-protein kinase Ras-related protein Rab-27A SWI/SNF complex subunit SMARCC1 SWI/SNF complex subunit SMARCC2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 Transcription activator BRG1 Transcription factor SOX-10 Tyrosinase Unconventional myosin-Va Upstream stimulatory factor 1 Zinc finger protein DPF3 Zinc finger protein neuro-d4 Zinc finger protein ubi-d4	O14497 O75177 O96019 P14679 P17643 P22415 P31751 P35222 P40126 P40967 P51159 P51531 P51532 P51810 P56693 P60709 Q12824 Q15532 Q16655 Q4VC05 Q6STE5 Q8NFD5 Q8TAQ2 Q8WUZ0 Q92782 Q92784 Q92785 Q92922 Q92925 Q969G3 Q96GM5 Q9BQE9 Q9UJU2 Q9Y4I1	ACTB ACTL6A AKT2 ARID1A ARID1B BAF155 BAF170 BAF190A BAF190B BAF250 BAF250A BAF250B BAF45B BAF45C BAF45D BAF47 BAF53 BAF53A BAF57 BAF60A BAF60B BAF60C BCL7A BCL7B BCL7C BHLHB11 BRG1 BRM C1orf4 CAS2 CERD4 CREST CTNNB CTNNB1 D12S53E DAN15 DCT DPF1 DPF2 DPF3 GPR143 INI1 INO80K KIAA0693 KIAA1235 LEF1 MART1 MLANA MYH12 MYO5A NEUD4 OA1 OSA1 OSA2 PMEL PMEL17 RAB27 RAB27A REQ SILV SMARCA2 SMARCA4 SMARCB1 SMARCC1 SMARCC2 SMARCD1 SMARCD2 SMARCD3 SMARCE1 SMARCF1 SNF2A SNF2B SNF2L2 SNF2L4 SNF5L1 SOX10 SS18 SS18L1 SSXT SYT TYR TYRP TYRP1 TYRP2 TYRRP UBID4 USF USF1	Homo sapiens (human)
Growth hormone receptor signaling	Chorionic somatomammotropin hormone 1 Cytokine-inducible SH2-containing protein Disintegrin and metalloproteinase domain-containing protein 17 Growth hormone receptor Growth hormone variant Insulin receptor substrate 1 Insulin receptor substrate 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Prolactin receptor Prolactin Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Somatotropin Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 2 Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn Tyrosine-protein phosphatase non-receptor type 1 Tyrosine-protein phosphatase non-receptor type 6	O14508 O14543 O15524 O60674 P01236 P01241 P01242 P07948 P0DML2 P10912 P16471 P18031 P27361 P28482 P29350 P35568 P40763 P42224 P42229 P51692 P78536 Q9NSE2 Q9Y4H2	ADAM17 APRF CIS2 CIS3 CISH CSH1 CSVP ERK1 ERK2 G18 GH1 GH2 GHR HCP IRS1 IRS2 JAK2 JTK8 LYN MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 PRL PRLR PTP1B PTP1C PTPN1 PTPN6 SOCS1 SOCS2 SOCS3 SSI1 SSI2 SSI3 STAT1 STAT3 STAT5 STAT5A STAT5B STATI2 TACE TIP3	Homo sapiens (human)
Negative regulation of FLT3	E3 ubiquitin-protein ligase CBL Fms-related tyrosine kinase 3 ligand Polyubiquitin-B Polyubiquitin-C Receptor-type tyrosine-protein kinase FLT3 Receptor-type tyrosine-protein phosphatase eta SH2B adapter protein 3 Src-like-adapter 2 Src-like-adapter Suppressor of cytokine signaling 2 Suppressor of cytokine signaling 6 Tyrosine-protein kinase ABL2 Tyrosine-protein kinase CSK Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14508 O14544 P0CG47 P0CG48 P22681 P36888 P41240 P42684 P49771 P62979 P62987 Q12913 Q13239 Q9H6Q3 Q9UQQ2	ABL2 ABLL ARG C20orf156 CBL CBL2 CD135 CIS2 CIS4 CSK DEP1 FLK2 FLT3 FLT3LG LNK PTPRJ RNF55 RPS27A SH2B3 SLA SLA2 SLAP SLAP1 SLAP2 SOCS2 SOCS4 SOCS6 SSI2 STATI2 STK1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
ERBB2 Regulates Cell Motility	Epidermal growth factor receptor Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protein MEMO1 Protein diaphanous homolog 1 Receptor tyrosine-protein kinase erbB-2 Transforming protein RhoA	O14511 O14944 O60610 P00533 P01133 P04626 P35070 P56975 P61586 Q02297 Q8WWG1 Q99075 Q9Y316	ARH12 ARHA BTC C2orf4 DIAP1 DIAPH1 DTR DTS EGF EGFR ERBB ERBB1 ERBB2 EREG GGF HBEGF HEGFL HER1 HER2 HGL HRGA MEMO MEMO1 MLN19 NDF NEU NGL NRG1 NRG2 NRG3 NRG4 NS5ATP7 NTAK RHO12 RHOA SMDF	Homo sapiens (human)
Nuclear signaling by ERBB4	Apolipoprotein E Arf-GAP with dual PH domain-containing protein 1 Beta-casein Disintegrin and metalloproteinase domain-containing protein 17 Estrogen receptor Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Glial fibrillary acidic protein Max dimerization protein 4 Nicastrin Nuclear receptor corepressor 1 Presenilin-1 Presenilin-2 Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Progesterone receptor Proheparin-binding EGF-like growth factor Protein S100-B Proto-oncogene tyrosine-protein kinase Src SPARC Signal transducer and activator of transcription 5A Stathmin Stromal cell-derived factor 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 Transcriptional coactivator YAP1 WW domain-containing oxidoreductase	O14511 O14944 O75376 O75689 P02649 P03372 P04271 P05814 P06401 P09486 P12931 P14136 P16949 P35070 P42229 P46937 P48061 P49768 P49810 P56975 P78536 Q02297 Q14582 Q8WW43 Q8WWG1 Q92542 Q96BI3 Q99075 Q9NYJ8 Q9NZ42 Q9NZC7	AD3 AD4 ADAM17 ADAP1 APH1A APH1B APOE BHLHC12 BTC C1orf215 CASB CENTA1 CSN2 CSVP CXCL12 DTR DTS EREG ESR ESR1 FOR GFAP GGF HBEGF HEGFL HGL HRGA KIAA0253 KIAA0733 KIAA1047 LAP18 MAD4 MAP3K7IP2 MXD4 NCOR1 NCSTN NDF NR3A1 NR3C3 NRG1 NRG2 NRG3 NRG4 NTAK ON OP18 PEN2 PGR PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 S100B SDF1 SDF1A SDF1B SDR41C1 SMDF SPARC SRC SRC1 STAT5 STAT5A STM2 STMN1 TAB2 TACE WOX1 WWOX YAP1 YAP65	Homo sapiens (human)
Signaling by ERBB2 KD Mutants	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Epidermal growth factor receptor Erbin GRB2-associated-binding protein 1 GTPase HRas GTPase NRas Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Receptor tyrosine-protein kinase erbB-2 SHC-transforming protein 1 Son of sevenless homolog 1	O14511 O14944 P00533 P01111 P01112 P01133 P04626 P07900 P19174 P27986 P29353 P35070 P42336 P56975 Q02297 Q07889 Q13480 Q16543 Q8WWG1 Q96RT1 Q99075	BTC CDC37 CDC37A DTR DTS EGF EGFR ERBB ERBB1 ERBB2 ERBB2IP ERBIN EREG GAB1 GGF GRB1 HBEGF HEGFL HER1 HER2 HGL HRAS HRAS1 HRGA HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NDF NEU NGL NRAS NRG1 NRG2 NRG3 NRG4 NTAK PIK3CA PIK3R1 PLC1 PLCG1 SHC SHC1 SHCA SMDF SOS1	Homo sapiens (human)
Signaling by ERBB2 TMD/JMD mutants	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Epidermal growth factor receptor Erbin GTPase HRas GTPase NRas Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Receptor tyrosine-protein kinase erbB-2 SHC-transforming protein 1 Son of sevenless homolog 1	O14511 O14944 P00533 P01111 P01112 P01133 P04626 P07900 P19174 P29353 P35070 P56975 Q02297 Q07889 Q16543 Q8WWG1 Q96RT1 Q99075	BTC CDC37 CDC37A DTR DTS EGF EGFR ERBB ERBB1 ERBB2 ERBB2IP ERBIN EREG GGF HBEGF HEGFL HER1 HER2 HGL HRAS HRAS1 HRGA HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NDF NEU NGL NRAS NRG1 NRG2 NRG3 NRG4 NTAK PLC1 PLCG1 SHC SHC1 SHCA SMDF SOS1	Homo sapiens (human)
SHC1 events in ERBB2 signaling	Epidermal growth factor receptor GTPase HRas GTPase NRas Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protein kinase C alpha type Protein kinase C delta type Protein kinase C epsilon type Receptor tyrosine-protein kinase erbB-2 SHC-transforming protein 1 Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 12	O14511 O14944 P00533 P01111 P01112 P01133 P04626 P17252 P29353 P35070 P56975 Q02156 Q02297 Q05209 Q05655 Q07889 Q8WWG1 Q99075	BTC DTR DTS EGF EGFR ERBB ERBB1 ERBB2 EREG GGF HBEGF HEGFL HER1 HER2 HGL HRAS HRAS1 HRGA MLN19 NDF NEU NGL NRAS NRG1 NRG2 NRG3 NRG4 NTAK PKCA PKCD PKCE PRKACA PRKCA PRKCD PRKCE PTPN12 SHC SHC1 SHCA SMDF SOS1	Homo sapiens (human)

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