GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1426 - 1450** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism	GlyTouCan ID
Breakdown of the nuclear lamina	Caspase-6 Lamin-B1	P20700 P55212	CASP6 LMN2 LMNB LMNB1 MCH2	Homo sapiens (human)
TRIF-mediated programmed cell death	Caspase-8 FAS-associated death domain protein Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Receptor-interacting serine/threonine-protein kinase 1 Receptor-interacting serine/threonine-protein kinase 3 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 Toll-like receptor 4	O00206 P08571 Q13158 Q13546 Q14790 Q86XR7 Q8IUC6 Q9Y572 Q9Y6Y9	CASP8 CD14 ESOP1 FADD LY96 MCH5 MD2 MORT1 PRVTIRB RIP RIP1 RIP3 RIPK1 RIPK3 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAM TRIF	Homo sapiens (human)
Regulation of NF-kappa B signaling	Caspase-8 Cellular tumor antigen p53 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibitor of nuclear factor kappa-B kinase-interacting protein Leucine-rich repeat-containing protein 14 NEDD4-binding protein 1 NF-kappa-B essential modulator NLR family member X1 Polyubiquitin-B Polyubiquitin-C Protein NLRC5 TNF receptor-associated factor 2 TNF receptor-associated factor 6 Ubiquitin carboxyl-terminal hydrolase 14 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Ubl carboxyl-terminal hydrolase 18	O14920 O15111 O75113 P04637 P0CG47 P0CG48 P54578 P62979 P62987 Q12933 Q14790 Q15048 Q70UQ0 Q86UT6 Q86WI3 Q9UMW8 Q9Y4K3 Q9Y6K9	CASP8 CHUK FIP3 IKBIP IKBKB IKBKG IKIP IKKA IKKB ISG43 KIAA0014 KIAA0615 LRRC14 MCH5 N4BP1 NEMO NLRC5 NLRX1 NOD27 NOD4 NOD5 NOD9 P53 RNF85 RPS27A TCF16 TGT TP53 TRAF2 TRAF6 TRAP3 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 USP14 USP18	Homo sapiens (human)
TLR3-mediated TICAM1-dependent programmed cell death	Caspase-8 FAS-associated death domain protein Receptor-interacting serine/threonine-protein kinase 1 Receptor-interacting serine/threonine-protein kinase 3 TIR domain-containing adapter molecule 1 Toll-like receptor 3	O15455 Q13158 Q13546 Q14790 Q8IUC6 Q9Y572	CASP8 FADD MCH5 MORT1 PRVTIRB RIP RIP1 RIP3 RIPK1 RIPK3 TICAM1 TLR3 TRIF	Homo sapiens (human)
Defective RIPK1-mediated regulated necrosis	Caspase-8 FAS-associated death domain protein Receptor-interacting serine/threonine-protein kinase 1 TNF receptor-associated factor 2 Tumor necrosis factor receptor type 1-associated DEATH domain protein	Q12933 Q13158 Q13546 Q14790 Q15628	CASP8 FADD MCH5 MORT1 RIP RIP1 RIPK1 TRADD TRAF2 TRAP3	Homo sapiens (human)
Class C/3 (Metabotropic glutamate/pheromone receptors)	Extracellular calcium-sensing receptor G-protein coupled receptor family C group 6 member A Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2 Metabotropic glutamate receptor 1 Metabotropic glutamate receptor 2 Metabotropic glutamate receptor 3 Metabotropic glutamate receptor 4 Metabotropic glutamate receptor 5 Metabotropic glutamate receptor 6 Metabotropic glutamate receptor 7 Metabotropic glutamate receptor 8 Taste receptor type 1 member 1 Taste receptor type 1 member 2 Taste receptor type 1 member 3 Taste receptor type 2 member 10 Taste receptor type 2 member 13 Taste receptor type 2 member 14 Taste receptor type 2 member 16 Taste receptor type 2 member 19 Taste receptor type 2 member 1 Taste receptor type 2 member 20 Taste receptor type 2 member 30 Taste receptor type 2 member 31 Taste receptor type 2 member 38 Taste receptor type 2 member 39 Taste receptor type 2 member 3 Taste receptor type 2 member 40 Taste receptor type 2 member 41 Taste receptor type 2 member 42 Taste receptor type 2 member 43 Taste receptor type 2 member 45 Taste receptor type 2 member 46 Taste receptor type 2 member 4 Taste receptor type 2 member 50 Taste receptor type 2 member 5 Taste receptor type 2 member 60 Taste receptor type 2 member 7 Taste receptor type 2 member 8 Taste receptor type 2 member 9	O00222 O15303 O75899 P41180 P41594 P59533 P59534 P59535 P59536 P59537 P59538 P59539 P59540 P59541 P59542 P59543 P59544 P59551 Q13255 Q14416 Q14831 Q14832 Q14833 Q5T6X5 Q7RTR8 Q7RTX0 Q7RTX1 Q8TE23 Q9NYV7 Q9NYV8 Q9NYV9 Q9NYW0 Q9NYW1 Q9NYW2 Q9NYW3 Q9NYW4 Q9NYW5 Q9NYW6 Q9NYW7 Q9UBS5	CASR GABBR1 GABBR2 GPR51 GPR59 GPR60 GPR70 GPR71 GPRC1A GPRC1B GPRC1C GPRC1D GPRC1E GPRC1F GPRC1G GPRC1H GPRC2A GPRC3A GPRC3B GPRC6A GRM1 GRM2 GRM3 GRM4 GRM5 GRM6 GRM7 GRM8 MGLUR1 MGLUR2 MGLUR3 MGLUR4 MGLUR5 MGLUR6 MGLUR7 MGLUR8 PCAR1 PTC T1R1 T1R2 T1R3 TAS1R1 TAS1R2 TAS1R3 TAS2R1 TAS2R10 TAS2R13 TAS2R14 TAS2R16 TAS2R19 TAS2R20 TAS2R23 TAS2R3 TAS2R30 TAS2R31 TAS2R38 TAS2R39 TAS2R4 TAS2R40 TAS2R41 TAS2R42 TAS2R43 TAS2R44 TAS2R45 TAS2R46 TAS2R47 TAS2R48 TAS2R49 TAS2R5 TAS2R50 TAS2R55 TAS2R60 TAS2R7 TAS2R8 TAS2R9 TR1 TR2 TR3	Homo sapiens (human)	G58161NS
Trafficking and processing of endosomal TLR	Cathepsin B Cathepsin K Cathepsin L2 Cathepsin S Endoplasmin Legumain Procathepsin L Protein canopy homolog 3 Protein unc-93 homolog B1 Toll-like receptor 3 Toll-like receptor 7 Toll-like receptor 8 Toll-like receptor 9	O15455 O60911 P07711 P07858 P14625 P25774 P43235 Q99538 Q9BT09 Q9H1C4 Q9NR96 Q9NR97 Q9NYK1	CATL2 CNPY3 CPSB CTG4A CTSB CTSK CTSL CTSL1 CTSL2 CTSO CTSO2 CTSS CTSU CTSV ERDA5 GRP94 HSP90B1 HSPC4 LGMN PRAT4A PRSC1 TLR3 TLR7 TLR8 TLR9 TNRC5 TRA1 UNC93 UNC93B UNC93B1	Homo sapiens (human)
RAB geranylgeranylation	Geranylgeranyl transferase type-2 subunit alpha Geranylgeranyl transferase type-2 subunit beta Protein tyrosine phosphatase type IVA 2 Rab proteins geranylgeranyltransferase component A 1 Rab proteins geranylgeranyltransferase component A 2 Ras-related protein Rab-10 Ras-related protein Rab-11A Ras-related protein Rab-11B Ras-related protein Rab-12 Ras-related protein Rab-13 Ras-related protein Rab-14 Ras-related protein Rab-15 Ras-related protein Rab-17 Ras-related protein Rab-18 Ras-related protein Rab-19 Ras-related protein Rab-1A Ras-related protein Rab-1B Ras-related protein Rab-20 Ras-related protein Rab-21 Ras-related protein Rab-22A Ras-related protein Rab-23 Ras-related protein Rab-24 Ras-related protein Rab-25 Ras-related protein Rab-26 Ras-related protein Rab-27A Ras-related protein Rab-27B Ras-related protein Rab-2A Ras-related protein Rab-2B Ras-related protein Rab-30 Ras-related protein Rab-31 Ras-related protein Rab-32 Ras-related protein Rab-33A Ras-related protein Rab-33B Ras-related protein Rab-34 Ras-related protein Rab-35 Ras-related protein Rab-36 Ras-related protein Rab-37 Ras-related protein Rab-38 Ras-related protein Rab-39A Ras-related protein Rab-39B Ras-related protein Rab-3A Ras-related protein Rab-3B Ras-related protein Rab-3C Ras-related protein Rab-3D Ras-related protein Rab-40A Ras-related protein Rab-40B Ras-related protein Rab-40C Ras-related protein Rab-41 Ras-related protein Rab-42 Ras-related protein Rab-43 Ras-related protein Rab-44 Ras-related protein Rab-4A Ras-related protein Rab-4B Ras-related protein Rab-5A Ras-related protein Rab-5B Ras-related protein Rab-5C Ras-related protein Rab-6A Ras-related protein Rab-6B Ras-related protein Rab-7L1 Ras-related protein Rab-7a Ras-related protein Rab-7b Ras-related protein Rab-8A Ras-related protein Rab-8B Ras-related protein Rab-9A Ras-related protein Rab-9B	A4D1S5 O00194 O14966 O95716 O95755 P20336 P20337 P20338 P20339 P20340 P24386 P26374 P51148 P51149 P51151 P51153 P51159 P53611 P57729 P57735 P59190 P61006 P61018 P61019 P61020 P61026 P61106 P62491 P62820 Q12829 Q12974 Q13636 Q13637 Q14088 Q14964 Q15286 Q15771 Q15907 Q5JT25 Q6IQ22 Q7Z6P3 Q86YS6 Q8N4Z0 Q8WUD1 Q8WXH6 Q92696 Q92930 Q969Q5 Q96AH8 Q96AX2 Q96DA2 Q96E17 Q96S21 Q9BZG1 Q9H082 Q9H0T7 Q9H0U4 Q9NP72 Q9NP90 Q9NRW1 Q9NX57 Q9UL25 Q9UL26 Q9ULC3 Q9ULW5	CATX8 CHM CHML GGTB GOV KIAA0118 MEL PRL2 PTP4A2 PTPCAAX2 RAB1 RAB10 RAB11 RAB11A RAB11B RAB12 RAB13 RAB14 RAB15 RAB16 RAB17 RAB18 RAB19 RAB19B RAB1A RAB1B RAB1C RAB2 RAB20 RAB21 RAB22 RAB22A RAB22B RAB23 RAB24 RAB25 RAB26 RAB27 RAB27A RAB27B RAB29 RAB2A RAB2B RAB30 RAB31 RAB32 RAB33A RAB33B RAB34 RAB35 RAB36 RAB37 RAB38 RAB39 RAB39A RAB39B RAB3A RAB3B RAB3C RAB3D RAB4 RAB40A RAB40B RAB40C RAB41 RAB42 RAB43 RAB44 RAB4A RAB4B RAB5 RAB5A RAB5B RAB5C RAB6 RAB6A RAB6B RAB7 RAB7A RAB7B RAB7L1 RAB8 RAB8A RAB8B RAB9 RAB9A RAB9B RAB9L RABGGTA RABGGTB RABL RABS10 RAH RARL RASL8C RAY REP1 REP2 SEC4L TCD YPT3	Homo sapiens (human)
NOSTRIN mediated eNOS trafficking	Actin nucleation-promoting factor WASL Caveolin-1 Dynamin-2 Nitric oxide synthase 3 Nostrin	O00401 P29474 P50570 Q03135 Q8IVI9	CAV CAV1 DNM2 DYN2 NOS3 NOSTRIN WASL	Homo sapiens (human)
Class A/1 (Rhodopsin-like receptors)	2-oxoglutarate receptor 1 Cannabinoid receptor 1 Cannabinoid receptor 2 Chemerin-like receptor 1 G-protein coupled bile acid receptor 1 G-protein coupled receptor 183 G-protein coupled receptor 35 G-protein coupled receptor 39 G-protein coupled receptor 4 G-protein coupled receptor 55 Hydroxycarboxylic acid receptor 2 Melatonin receptor type 1A Melatonin receptor type 1B N-arachidonyl glycine receptor Ovarian cancer G-protein coupled receptor 1 Platelet-activating factor receptor Probable G-protein coupled receptor 132 Psychosine receptor Succinate receptor 1	O43194 P21554 P25105 P32249 P34972 P46093 P48039 P49286 Q14330 Q15743 Q8IYL9 Q8TDS4 Q8TDU6 Q96P68 Q99788 Q9BXA5 Q9HC97 Q9UNW8 Q9Y2T6	CB2A CB2B CHEMR23 CMKLR1 CNR CNR1 CNR2 DEZ EBI2 G2A GPBAR1 GPCRW GPR109A GPR132 GPR18 GPR183 GPR35 GPR39 GPR4 GPR55 GPR65 GPR68 GPR80 GPR91 GPR99 HCA2 HCAR2 HM74A MTNR1A MTNR1B NIACR1 OGR1 OXGR1 P2RY15 P2Y15 PAFR PTAFR SUCNR1 TDAG8 TGR5	Homo sapiens (human)
RUNX2 regulates chondrocyte maturation	Core-binding factor subunit beta Histone deacetylase 4 Indian hedgehog protein Zinc finger protein GLI2	P10070 P56524 Q13951 Q14623	CBFB GLI2 HDAC4 IHH KIAA0288 THP	Homo sapiens (human)
FLT3 signaling by CBL mutants	E3 ubiquitin-protein ligase CBL Fms-related tyrosine kinase 3 ligand Polyubiquitin-B Polyubiquitin-C Receptor-type tyrosine-protein kinase FLT3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P0CG47 P0CG48 P22681 P36888 P49771 P62979 P62987	CBL CBL2 CD135 FLK2 FLT3 FLT3LG RNF55 RPS27A STK1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 E3 ubiquitin-protein ligase CBL Epidermal growth factor receptor GRB2-associated-binding protein 1 GTPase HRas GTPase NRas Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Polyubiquitin-B Polyubiquitin-C Pro-epidermal growth factor SHC-transforming protein 1 Son of sevenless homolog 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P00533 P01111 P01112 P01133 P07900 P0CG47 P0CG48 P19174 P22681 P27986 P29353 P42336 P62979 P62987 Q07889 Q13480 Q16543	CBL CBL2 CDC37 CDC37A EGF EGFR ERBB ERBB1 GAB1 GRB1 HER1 HRAS HRAS1 HSP90A HSP90AA1 HSPC1 HSPCA NRAS PIK3CA PIK3R1 PLC1 PLCG1 RNF55 RPS27A SHC SHC1 SHCA SOS1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Constitutive Signaling by EGFRvIII	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 E3 ubiquitin-protein ligase CBL Epidermal growth factor receptor GRB2-associated-binding protein 1 GTPase HRas GTPase NRas Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Pro-epidermal growth factor SHC-transforming protein 1 Son of sevenless homolog 1	P00533 P01111 P01112 P01133 P07900 P19174 P22681 P27986 P29353 P42336 Q07889 Q13480 Q16543	CBL CBL2 CDC37 CDC37A EGF EGFR ERBB ERBB1 GAB1 GRB1 HER1 HRAS HRAS1 HSP90A HSP90AA1 HSPC1 HSPCA NRAS PIK3CA PIK3R1 PLC1 PLCG1 RNF55 SHC SHC1 SHCA SOS1	Homo sapiens (human)
Negative regulation of FGFR2 signaling	E3 ubiquitin-protein ligase CBL Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Polyubiquitin-B Polyubiquitin-C Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O15520 O43320 O76093 P05230 P08620 P09038 P0CG47 P0CG48 P10767 P11487 P21781 P22681 P27361 P28482 P31371 P62979 P62987 Q06124 Q8WU20 Q9GZV9 Q9HCT0 Q9NP95	CBL CBL2 ERK1 ERK2 FGF1 FGF10 FGF16 FGF18 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB FRS2 HST HST2 HSTF1 HSTF2 HYPF INT2 KGF KS3 MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 PTP2C PTPN11 RNF55 RPS27A SHPTP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Negative regulation of FGFR4 signaling	Beta-klotho E3 ubiquitin-protein ligase CBL Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 19 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Polyubiquitin-B Polyubiquitin-C Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O43320 O76093 O95750 P05230 P08620 P09038 P0CG47 P0CG48 P10767 P22455 P22681 P27361 P28482 P31371 P62979 P62987 Q06124 Q86Z14 Q8WU20 Q9GZV9 Q9NP95	CBL CBL2 ERK1 ERK2 FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF9 FGFA FGFB FGFR4 FRS2 HST HST2 HSTF1 HSTF2 HYPF JTK2 KLB KS3 MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 PTP2C PTPN11 RNF55 RPS27A SHPTP2 TKF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Negative regulation of FGFR3 signaling	E3 ubiquitin-protein ligase CBL Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Polyubiquitin-B Polyubiquitin-C Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O43320 O76093 P05230 P08620 P09038 P0CG47 P0CG48 P22681 P27361 P28482 P31371 P62979 P62987 Q06124 Q8WU20 Q9GZV9 Q9NP95	CBL CBL2 ERK1 ERK2 FGF1 FGF16 FGF18 FGF2 FGF20 FGF23 FGF4 FGF9 FGFA FGFB FRS2 HST HSTF1 HYPF KS3 MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 PTP2C PTPN11 RNF55 RPS27A SHPTP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Defective CBLIF causes IFD	Cobalamin binding intrinsic factor	P27352	CBLIF GIF IFMH	Homo sapiens (human)
InlA-mediated entry of Listeria monocytogenes into host cells	Cadherin-1 Catenin beta-1 Catenin delta-1 E3 ubiquitin-protein ligase Hakai Internalin A Polyubiquitin-B Polyubiquitin-C Proto-oncogene tyrosine-protein kinase Src Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O60716 P0CG47 P0CG48 P0DJM0 P12830 P12931 P35222 P62979 P62987 Q75N03	CBLL1 CDH1 CDHE CTNNB CTNNB1 CTNND1 HAKAI KIAA0384 RNF188 RPS27A SRC SRC1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UVO inlA	Homo sapiens (human)
NFE2L2 regulating inflammation associated genes	C-C motif chemokine 2 CREB-binding protein Histone acetyltransferase p300 Nuclear factor erythroid 2-related factor 2 Transcription factor MafK	O60675 P13500 Q09472 Q16236 Q92793	CBP CCL2 CREBBP EP300 MAFK MCP1 NFE2L2 NRF2 P300 SCYA2	Homo sapiens (human)
CD209 (DC-SIGN) signaling	CD209 antigen CREB-binding protein GTPase HRas GTPase NRas Histone acetyltransferase p300 Intercellular adhesion molecule 2 Intercellular adhesion molecule 3 Nuclear factor NF-kappa-B p105 subunit RAF proto-oncogene serine/threonine-protein kinase Ribosomal protein S6 kinase alpha-5 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Transcription factor RelB Transcription factor p65 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	O75582 O75914 P01111 P01112 P04049 P06241 P07948 P13598 P17612 P19838 P22612 P22694 P32942 Q01201 Q04206 Q09472 Q13153 Q13177 Q92793 Q9NNX6	CBP CD209 CLEC4L CREBBP EP300 FYN HRAS HRAS1 ICAM2 ICAM3 JTK8 LYN MSK1 NFKB1 NFKB3 NRAS OPHN3 P300 PAK1 PAK2 PAK3 PKACA PRKACA PRKACB PRKACG RAF RAF1 RELA RELB RPS6KA5	Homo sapiens (human)
Phosphorylation of CD3 and TCR zeta chains	HLA class II histocompatibility antigen, DP alpha 1 chain HLA class II histocompatibility antigen, DP beta 1 chain HLA class II histocompatibility antigen, DQ alpha 1 chain HLA class II histocompatibility antigen, DQ alpha 2 chain HLA class II histocompatibility antigen, DQ beta 1 chain HLA class II histocompatibility antigen, DQ beta 2 chain HLA class II histocompatibility antigen, DR alpha chain HLA class II histocompatibility antigen, DR beta 3 chain HLA class II histocompatibility antigen, DR beta 4 chain HLA class II histocompatibility antigen, DR beta 5 chain HLA class II histocompatibility antigen, DRB1 beta chain Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 Receptor-type tyrosine-protein phosphatase C Receptor-type tyrosine-protein phosphatase eta T cell receptor alpha chain constant T cell receptor alpha variable 19 T cell receptor alpha variable 29/delta variable 5 T cell receptor alpha variable 8-4 T cell receptor beta constant 1 T cell receptor beta variable 12-3 T cell receptor beta variable 7-9 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD4 Tyrosine-protein kinase CSK Tyrosine-protein kinase Lck Tyrosine-protein phosphatase non-receptor type 22	A0A0A6YYK7 P01730 P01733 P01737 P01848 P01850 P01903 P01906 P01909 P01911 P01920 P04234 P04435 P04437 P04440 P05538 P06239 P07766 P08575 P09693 P13762 P20036 P41240 P79483 Q12913 Q30154 Q9NWQ8 Q9Y2R2	CBP CD3D CD3E CD3G CD4 CD45 CSK DEP1 HLA-DP1A HLA-DP1B HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB HLA-DQB1 HLA-DQB2 HLA-DRA HLA-DRA1 HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 HLA-DXA HLA-DXB HLASB LCK PAG PAG1 PTPN22 PTPN8 PTPRC PTPRJ T3D T3E T3G TCRA TCRBV12S3 TCRBV8S1 TRAC TRAV19 TRAV29DV5 TRAV8-4 TRBC1 TRBV12-3 TRBV7-9	Homo sapiens (human)
Notch-HLH transcription pathway	CREB-binding protein F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Histone acetyltransferase KAT2A Histone acetyltransferase KAT2B Histone deacetylase 11 Histone deacetylase 1 Histone deacetylase 2 Histone deacetylase 3 Histone deacetylase 4 Histone deacetylase 5 Histone deacetylase 6 Histone deacetylase 7 Histone deacetylase 8 Histone deacetylase 9 Mastermind-like domain-containing protein 1 Mastermind-like protein 1 Mastermind-like protein 2 Mastermind-like protein 3 Neurogenic locus notch homolog protein 1 Neurogenic locus notch homolog protein 2 Neurogenic locus notch homolog protein 3 Neurogenic locus notch homolog protein 4 Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 Polyamine deacetylase HDAC10 Recombining binding protein suppressor of hairless SNW domain-containing protein 1	O15379 O60907 O75376 P46531 P56524 Q04721 Q06330 Q13495 Q13547 Q13573 Q8IZL2 Q8WUI4 Q92585 Q92769 Q92793 Q92830 Q92831 Q969S8 Q96DB2 Q96JK9 Q99466 Q9BY41 Q9BZK7 Q9UBN7 Q9UKV0 Q9UM47 Q9UQL6 Q9Y618	CBP CG1 CREBBP CTG26 CXorf6 GCN5 GCN5L2 HDAC1 HDAC10 HDAC11 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC7A HDAC7B HDAC8 HDAC9 HDACL1 HDRP IGKJRB IGKJRB1 INT3 IRA1 KAT2A KAT2B KIAA0200 KIAA0288 KIAA0600 KIAA0744 KIAA0901 KIAA1047 KIAA1816 KIAA1819 MAML1 MAML2 MAML3 MAMLD1 MITR NCOR1 NCOR2 NOTCH1 NOTCH2 NOTCH3 NOTCH4 PCAF RBPJ RBPJK RBPSUH RPD3L1 SKIIP SKIP SNW1 TAN1 TBL1 TBL1X TBL1XR1 TBLR1	Homo sapiens (human)
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production	CREB-binding protein Catenin beta-1 Histone acetyltransferase p300 Interferon regulatory factor 3 Leucine-rich repeat flightless-interacting protein 1	P35222 Q09472 Q14653 Q32MZ4 Q92793	CBP CREBBP CTNNB CTNNB1 EP300 GCF2 IRF3 LRRFIP1 P300 TRIP	Homo sapiens (human)
TRAF6 mediated IRF7 activation	Antiviral innate immune response receptor RIG-I CREB-binding protein E3 ubiquitin-protein ligase RNF135 E3 ubiquitin-protein ligase TRIM4 E3 ubiquitin/ISG15 ligase TRIM25 Histone acetyltransferase p300 Inhibitor of nuclear factor kappa-B kinase subunit epsilon Interferon alpha-1/13 Interferon alpha-10 Interferon alpha-14 Interferon alpha-16 Interferon alpha-17 Interferon alpha-21 Interferon alpha-2 Interferon alpha-4 Interferon alpha-5 Interferon alpha-6 Interferon alpha-7 Interferon alpha-8 Interferon beta Interferon regulatory factor 3 Interferon regulatory factor 7 Interferon-induced helicase C domain-containing protein 1 Mitochondrial antiviral-signaling protein Serine/threonine-protein kinase TBK1 Suppressor of IKBKE 1 TNF receptor-associated factor 2 TNF receptor-associated factor 6 TRAF family member-associated NF-kappa-B activator	O95786 P01562 P01563 P01566 P01567 P01568 P01569 P01570 P01571 P01574 P05013 P05014 P05015 P32881 Q09472 Q12933 Q14164 Q14258 Q14653 Q7Z434 Q8IUD6 Q92793 Q92844 Q92985 Q9BRV8 Q9BYX4 Q9C037 Q9UHD2 Q9Y4K3	CBP CREBBP DDX58 EFP EP300 IFB IFIH1 IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA2A IFNA2B IFNA2C IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNB IFNB1 IKBKE IKKE IKKI IPS1 IRF3 IRF7 ITRAF KIAA0151 KIAA1271 MAVS MDA5 NAK P300 RH116 RIGI RNF135 RNF147 RNF85 RNF87 SIKE SIKE1 TANK TBK1 TRAF2 TRAF6 TRAP3 TRIM25 TRIM4 VISA ZNF147	Homo sapiens (human)

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