GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **301 - 325** of **2090** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	GlyTouCan ID
Regulation by c-FLIP	Caspase-8 FAS-associated death domain protein Receptor-interacting serine/threonine-protein kinase 1 TNF receptor-associated factor 2 Tumor necrosis factor ligand superfamily member 10 Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor type 1-associated DEATH domain protein	O00220 O14763 P25445 P48023 P50591 Q12933 Q13158 Q13546 Q14790 Q15628	APO2 APO2L APT1 APT1LG1 CASP8 CD95L DR4 DR5 FADD FAS FAS1 FASL FASLG KILLER MCH5 MORT1 RIP RIP1 RIPK1 TNFRSF10A TNFRSF10B TNFRSF6 TNFSF10 TNFSF6 TRADD TRAF2 TRAIL TRAILR1 TRAILR2 TRAP3 TRICK2 ZTNFR9
Dimerization of procaspase-8	Caspase-8 FAS-associated death domain protein Receptor-interacting serine/threonine-protein kinase 1 TNF receptor-associated factor 2 Tumor necrosis factor ligand superfamily member 10 Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor type 1-associated DEATH domain protein	O00220 O14763 P25445 P48023 P50591 Q12933 Q13158 Q13546 Q14790 Q15628	APO2 APO2L APT1 APT1LG1 CASP8 CD95L DR4 DR5 FADD FAS FAS1 FASL FASLG KILLER MCH5 MORT1 RIP RIP1 RIPK1 TNFRSF10A TNFRSF10B TNFRSF6 TNFSF10 TNFSF6 TRADD TRAF2 TRAIL TRAILR1 TRAILR2 TRAP3 TRICK2 ZTNFR9
Class C/3 (Metabotropic glutamate/pheromone receptors)	Extracellular calcium-sensing receptor G-protein coupled receptor family C group 6 member A Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2 Metabotropic glutamate receptor 1 Metabotropic glutamate receptor 2 Metabotropic glutamate receptor 3 Metabotropic glutamate receptor 4 Metabotropic glutamate receptor 5 Metabotropic glutamate receptor 6 Metabotropic glutamate receptor 7 Metabotropic glutamate receptor 8 Taste receptor type 1 member 1 Taste receptor type 1 member 2 Taste receptor type 1 member 3 Taste receptor type 2 member 10 Taste receptor type 2 member 13 Taste receptor type 2 member 14 Taste receptor type 2 member 16 Taste receptor type 2 member 19 Taste receptor type 2 member 1 Taste receptor type 2 member 20 Taste receptor type 2 member 30 Taste receptor type 2 member 31 Taste receptor type 2 member 38 Taste receptor type 2 member 39 Taste receptor type 2 member 3 Taste receptor type 2 member 40 Taste receptor type 2 member 41 Taste receptor type 2 member 42 Taste receptor type 2 member 43 Taste receptor type 2 member 45 Taste receptor type 2 member 46 Taste receptor type 2 member 4 Taste receptor type 2 member 50 Taste receptor type 2 member 5 Taste receptor type 2 member 60 Taste receptor type 2 member 7 Taste receptor type 2 member 8 Taste receptor type 2 member 9	O00222 O15303 O75899 P41180 P41594 P59533 P59534 P59535 P59536 P59537 P59538 P59539 P59540 P59541 P59542 P59543 P59544 P59551 Q13255 Q14416 Q14831 Q14832 Q14833 Q5T6X5 Q7RTR8 Q7RTX0 Q7RTX1 Q8TE23 Q9NYV7 Q9NYV8 Q9NYV9 Q9NYW0 Q9NYW1 Q9NYW2 Q9NYW3 Q9NYW4 Q9NYW5 Q9NYW6 Q9NYW7 Q9UBS5	CASR GABBR1 GABBR2 GPR51 GPR59 GPR60 GPR70 GPR71 GPRC1A GPRC1B GPRC1C GPRC1D GPRC1E GPRC1F GPRC1G GPRC1H GPRC2A GPRC3A GPRC3B GPRC6A GRM1 GRM2 GRM3 GRM4 GRM5 GRM6 GRM7 GRM8 MGLUR1 MGLUR2 MGLUR3 MGLUR4 MGLUR5 MGLUR6 MGLUR7 MGLUR8 PCAR1 PTC T1R1 T1R2 T1R3 TAS1R1 TAS1R2 TAS1R3 TAS2R1 TAS2R10 TAS2R13 TAS2R14 TAS2R16 TAS2R19 TAS2R20 TAS2R23 TAS2R3 TAS2R30 TAS2R31 TAS2R38 TAS2R39 TAS2R4 TAS2R40 TAS2R41 TAS2R42 TAS2R43 TAS2R44 TAS2R45 TAS2R46 TAS2R47 TAS2R48 TAS2R49 TAS2R5 TAS2R50 TAS2R55 TAS2R60 TAS2R7 TAS2R8 TAS2R9 TR1 TR2 TR3	G58161NS
Peptide ligand-binding receptors	Adrenocorticotropic hormone receptor Angiotensinogen Apelin receptor Apelin Atypical chemokine receptor 1 B1 bradykinin receptor B2 bradykinin receptor Bombesin receptor subtype-3 C3a anaphylatoxin chemotactic receptor C5a anaphylatoxin chemotactic receptor 1 C5a anaphylatoxin chemotactic receptor 2 Cholecystokinin receptor type A Cholecystokinin Complement C3 Complement C5 Cortistatin Delta-type opioid receptor Endoplasmic reticulum membrane adapter protein XK Endothelin receptor type B Endothelin-1 receptor Endothelin-1 Endothelin-2 Endothelin-3 Endothelin-converting enzyme 1 Endothelin-converting enzyme 2 G-protein coupled estrogen receptor 1 G-protein coupled receptor 37-like 1 Galanin peptides Galanin receptor type 1 Galanin receptor type 2 Galanin receptor type 3 Gastrin-releasing peptide receptor Gastrin-releasing peptide Gastrin/cholecystokinin type B receptor Growth hormone secretagogue receptor type 1 Interleukin-8 Kappa-type opioid receptor Kell blood group glycoprotein KiSS-1 receptor Kininogen-1 Melanin-concentrating hormone receptor 1 Melanin-concentrating hormone receptor 2 Melanocortin receptor 3 Melanocortin receptor 4 Melanocortin receptor 5 Melanocyte-stimulating hormone receptor Metastasis-suppressor KiSS-1 Motilin receptor Mu-type opioid receptor Neurolysin, mitochondrial Neuromedin-B receptor Neuromedin-B Neuromedin-S Neuromedin-U receptor 1 Neuromedin-U receptor 2 Neuromedin-U Neuropeptide B Neuropeptide S receptor Neuropeptide S Neuropeptide W Neuropeptide Y receptor type 1 Neuropeptide Y receptor type 2 Neuropeptide Y receptor type 4 Neuropeptide Y receptor type 5 Neuropeptides B/W receptor type 1 Neuropeptides B/W receptor type 2 Neurotensin receptor type 1 Neurotensin receptor type 2 Neurotensin/neuromedin N Nociceptin receptor Pancreatic polypeptide prohormone Peptide YY Prepronociceptin Pro-MCH Pro-neuropeptide Y Pro-opiomelanocortin Pro-thyrotropin-releasing hormone Proenkephalin-A Proenkephalin-B Prokineticin receptor 1 Prokineticin receptor 2 Prokineticin-1 Prokineticin-2 Prolactin-releasing peptide receptor Prolactin-releasing peptide Promotilin Prosaposin receptor GPR37 Prosaposin Proteinase-activated receptor 1 Proteinase-activated receptor 2 Proteinase-activated receptor 3 Proteinase-activated receptor 4 Prothrombin Somatostatin receptor type 1 Somatostatin receptor type 2 Somatostatin receptor type 3 Somatostatin receptor type 4 Somatostatin receptor type 5 Somatostatin Thyrotropin-releasing hormone receptor Type-1 angiotensin II receptor Type-2 angiotensin II receptor Urotensin-2 receptor Urotensin-2 Urotensin-2B	O00230 O00254 O15354 O43193 O43603 O60755 O60883 O95399 O95665 P00734 P01019 P01024 P01031 P01042 P01189 P01210 P01213 P01298 P01303 P05305 P06307 P07492 P07602 P08949 P0C0P6 P0DPD6 P10082 P10145 P12872 P14138 P20382 P20396 P20800 P21730 P22466 P23276 P24530 P25101 P25116 P25929 P28336 P30411 P30550 P30556 P30872 P30874 P30989 P30990 P31391 P32238 P32239 P32245 P32247 P32745 P33032 P34981 P35346 P35372 P35414 P41143 P41145 P41146 P41968 P42892 P46663 P47211 P48145 P48146 P48645 P49146 P49683 P50052 P50391 P51811 P55085 P58294 P61278 P81277 Q01718 Q01726 Q13519 Q15726 Q15761 Q16570 Q16581 Q5H8A3 Q6W5P4 Q765I0 Q8N729 Q8NFJ6 Q8NG41 Q8TCW9 Q92847 Q969F8 Q969V1 Q96RI0 Q99527 Q99705 Q9BYT8 Q9GZQ4 Q9HB89 Q9HC23 Q9P296 Q9UKP6 Q9ULZ1	ACKR1 ACTHR AGT AGTBP AGTR1 AGTR1A AGTR1B AGTR2 AGTRL1 APEL APJ APLN APLNR AT2R1 AT2R1B AXOR12 AZ3B BDK BDKRB1 BDKRB2 BKR2 BRADYB1 BRS3 BV8 C3 C3AR1 C3R1 C5 C5AR C5AR1 C5AR2 C5L2 C5R1 CCK CCKAR CCKBR CCKRA CCKRB CEPR CF2R CMKRL2 CORT CPAMD1 CPAMD4 CXCL8 DARC DRY12 ECE1 ECE2 EDN1 EDN2 EDN3 EDNRA EDNRB ETA ETBRLP2 ETRA ETRB F2 F2R F2RL1 F2RL2 F2RL3 FY GAL GAL1 GALN GALNR GALNR1 GALNR2 GALNR3 GALR1 GALR2 GALR3 GHSR GLBA GLNN GPD GPER GPER1 GPR10 GPR11 GPR14 GPR145 GPR154 GPR24 GPR30 GPR37 GPR37L1 GPR38 GPR54 GPR66 GPR7 GPR73 GPR73L1 GPR77 GPR8 GPRA GR3 GRP GRPR HNFAG09 IL8 KEL KIAA0604 KIAA1226 KISS1 KISS1R KNG KNG1 MC1R MC2R MC3R MC4R MC5R MCH MCHR1 MCHR2 MLN MLNR MOR1 MSHR MTLR MTLR1 NLN NMB NMBR NMS NMU NMU2R NMUR1 NMUR2 NPB NPBWR1 NPBWR2 NPS NPSR1 NPW NPY NPY1R NPY2R NPY4R NPY5R NPYR NPYR5 NPYY1 NTRR NTS NTSR1 NTSR2 OFQ OOR OPRD OPRD1 OPRK OPRK1 OPRL1 OPRM1 ORL1 PAR1 PAR2 PAR3 PAR4 PDYN PENK PGR14 PKR1 PKR2 PMCH PNOC PNP POMC PPL7 PPL8 PPNPB PPNPW PPY PPYR1 PRH PRLH PRLHR PROK1 PROK2 PROKR1 PROKR2 PSAP PYY SAP1 SERPINA8 SLC1 SLT SST SSTR1 SSTR2 SSTR3 SSTR4 SSTR5 TGR1 TR TRH TRHR URP UTS2 UTS2B UTS2D UTS2R XK XKR1 XRG1
Assembly of the pre-replicative complex	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division control protein 6 homolog Cell division cycle protein 16 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog DNA replication factor Cdt1 DNA replication licensing factor MCM2 DNA replication licensing factor MCM3 DNA replication licensing factor MCM4 DNA replication licensing factor MCM5 DNA replication licensing factor MCM6 DNA replication licensing factor MCM7 Fizzy-related protein homolog Geminin Origin recognition complex subunit 1 Origin recognition complex subunit 2 Origin recognition complex subunit 3 Origin recognition complex subunit 4 Origin recognition complex subunit 5 Origin recognition complex subunit 6 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00233 O00487 O00762 O14818 O43242 O43913 O43929 O75496 O75832 P0CG47 P0CG48 P17980 P20618 P25205 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P30260 P33991 P33992 P33993 P35998 P40306 P43686 P48556 P49720 P49721 P49736 P51665 P51668 P51965 P55036 P60006 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q06323 Q13042 Q13200 Q13415 Q13416 Q14566 Q15008 Q16401 Q16763 Q8NHZ8 Q92530 Q96DE5 Q99436 Q99460 Q99741 Q9H1A4 Q9H211 Q9NYG5 Q9UBD5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UL46 Q9UM11 Q9UM13 Q9UNM6 Q9Y5N6	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 BM28 C10orf104 C11orf51 C7orf76 C9orf17 CCNL1 CDC16 CDC18L CDC21 CDC23 CDC26 CDC27 CDC46 CDC47 CDC6 CDCL1 CDH1 CDT1 CENP-27 D0S1430E D17S978E DSS1 E2EPF FYR FZR FZR1 GMNN HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0030 KIAA0072 KIAA0107 KIAA1242 KIAA1406 LATHEO LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MECL1 MIP224 MOV34L MSS1 NU ORC1 ORC1L ORC2 ORC2L ORC3 ORC3L ORC4 ORC4L ORC5 ORC5L ORC6 ORC6L PARC1 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSMF1 RING10 RING12 RPS27A SEM1 SFT SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 TSG24 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S X Y Y2 Z
Autodegradation of Cdh1 by Cdh1:APC/C	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Fizzy-related protein homolog Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00233 O00487 O00762 O14818 O43242 O75832 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P30260 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P51668 P51965 P55036 P60006 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q06323 Q13042 Q13200 Q15008 Q16401 Q16763 Q8NHZ8 Q92530 Q96DE5 Q99436 Q99460 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UL46 Q9UM11 Q9UM13 Q9UNM6	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 C10orf104 C11orf51 C7orf76 C9orf17 CDC16 CDC23 CDC26 CDC27 CDH1 CENP-27 D0S1430E D17S978E DSS1 E2EPF FYR FZR FZR1 HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0107 KIAA1242 KIAA1406 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NU PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSMF1 RING10 RING12 RPS27A SEM1 SFT SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 TSG24 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S X Y Y2 Z
SCF(Skp2)-mediated degradation of p27/p21	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-1 Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 Cyclin-dependent kinase 4 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B Cyclin-dependent kinases regulatory subunit 1 G1/S-specific cyclin-D1 G1/S-specific cyclin-E1 G1/S-specific cyclin-E2 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein-tyrosine kinase 6 S-phase kinase-associated protein 1 S-phase kinase-associated protein 2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00233 O00487 O14818 O43242 O75832 O96020 P0CG47 P0CG48 P11802 P17980 P20248 P20618 P24385 P24864 P24941 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P38936 P40306 P43686 P46527 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61024 P61289 P62191 P62195 P62333 P62979 P62987 P63208 P78396 Q06323 Q13200 Q13309 Q13616 Q13882 Q15008 Q16401 Q92530 Q99436 Q99460 Q9UL46 Q9UNM6	BCL1 BRK C7orf76 CAP20 CCN1 CCNA CCNA1 CCNA2 CCND1 CCNE CCNE1 CCNE2 CDK2 CDK4 CDKN1 CDKN1A CDKN1B CDKN2 CIP1 CKS1 CKS1B CUL1 DSS1 EMC19 FBXL1 HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0107 KIP1 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MDA6 MECL1 MIP224 MOV34L MSS1 NU OCP2 PFAAP4 PIC1 POH1 PRAD1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSMF1 PTK6 RING10 RING12 RPS27A SDI1 SEM1 SHFDG1 SHFM1 SKP1 SKP1A SKP2 SUG1 SUG2 TBP1 TBP7 TCEB1L TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WAF1 X Y Y2 Z p27
Regulation of RUNX3 expression and activity	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Core-binding factor subunit beta E3 ubiquitin-protein ligase Mdm2 E3 ubiquitin-protein ligase SMURF1 E3 ubiquitin-protein ligase SMURF2 Histone acetyltransferase p300 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proto-oncogene tyrosine-protein kinase Src Runt-related transcription factor 3 Transforming growth factor beta-1 proprotein Tumor suppressor ARF Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00233 O00487 O14818 O43242 O75832 P01137 P0CG47 P0CG48 P12931 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q00987 Q06323 Q09472 Q13200 Q13761 Q13951 Q15008 Q16401 Q8N726 Q92530 Q99436 Q99460 Q9HAU4 Q9HCE7 Q9UL46 Q9UNM6	AML2 C7orf76 CBFA3 CBFB CDKN2 CDKN2A DSS1 EP300 HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0107 KIAA1625 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MDM2 MECL1 MIP224 MLM MOV34L MSS1 NU P300 PEBP2A3 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSMF1 RING10 RING12 RPS27A RUNX3 SEM1 SHFDG1 SHFM1 SMURF1 SMURF2 SRC SRC1 SUG1 SUG2 TBP1 TBP7 TGFB TGFB1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 Z
Negative regulation of NOTCH4 signaling	14-3-3 protein zeta/delta 26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-1 E3 ubiquitin-protein ligase RBX1 Neurogenic locus notch homolog protein 4 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 RAC-alpha serine/threonine-protein kinase S-phase kinase-associated protein 1 Transforming acidic coiled-coil-containing protein 3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00233 O00487 O14818 O43242 O75832 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P31749 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62877 P62979 P62987 P63104 P63208 Q06323 Q13200 Q13616 Q15008 Q16401 Q92530 Q99436 Q99460 Q99466 Q9UL46 Q9UNM6 Q9Y6A5	AKT1 C7orf76 CUL1 DSS1 EMC19 ERIC1 HC2 HC3 HC8 HC9 HSPC IFI5111 INT3 KIAA0072 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NOTCH4 NU OCP2 PFAAP4 PKB POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSMF1 RAC RBX1 RING10 RING12 RNF75 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SUG1 SUG2 TACC3 TBP1 TBP7 TCEB1L TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 YWHAZ Z
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-1 E3 ubiquitin-protein ligase RBX1 F-box/WD repeat-containing protein 1A Glycogen synthase kinase-3 beta Nuclear factor erythroid 2-related factor 2 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 S-phase kinase-associated protein 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00233 O00487 O14818 O43242 O75832 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P49841 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62877 P62979 P62987 P63208 Q06323 Q13200 Q13616 Q15008 Q16236 Q16401 Q92530 Q99436 Q99460 Q9UL46 Q9UNM6 Q9Y297	BTRC BTRCP C7orf76 CUL1 DSS1 EMC19 FBW1A FBXW1A GSK3B HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NFE2L2 NRF2 NU OCP2 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSMF1 RBX1 RING10 RING12 RNF75 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SUG1 SUG2 TBP1 TBP7 TCEB1L TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 Z
ER Quality Control Compartment (ERQC)	Derlin-2 E3 ubiquitin-protein ligase AMFR E3 ubiquitin-protein ligase MARCHF6 E3 ubiquitin-protein ligase RNF103 E3 ubiquitin-protein ligase RNF139 E3 ubiquitin-protein ligase RNF185 E3 ubiquitin-protein ligase RNF5 E3 ubiquitin-protein ligase TRIM13 E3 ubiquitin-protein ligase synoviolin ER degradation-enhancing alpha-mannosidase-like protein 1 ER degradation-enhancing alpha-mannosidase-like protein 2 ER degradation-enhancing alpha-mannosidase-like protein 3 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase Polyubiquitin-B Polyubiquitin-C Protein OS-9 Protein sel-1 homolog 1 UDP-glucose UDP-glucose Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00237 O60337 O60858 P0CG47 P0CG48 P62979 P62987 Q13438 Q86TM6 Q8WU17 Q92611 Q96GF1 Q99942 Q9BV94 Q9BZQ6 Q9GZP9 Q9NYU1 Q9NYU2 Q9UBV2 Q9UKM7 Q9UKV5	AMFR C1orf22 C20orf31 C20orf49 DER2 DERL2 EDEM EDEM1 EDEM2 EDEM3 FLANA G16 GT HRD1 KIAA0212 KIAA0597 KIAA1810 LEU5 MAN1B1 MARCH6 MARCHF6 NG2 OS9 RFP2 RMA1 RNF103 RNF139 RNF176 RNF185 RNF45 RNF5 RNF77 RPS27A SEL1L SYVN1 TEB4 TRC8 TRIM13 TSA305 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UGCGL1 UGCGL2 UGGT UGGT1 UGGT2 UGT1 UGT2 UGTR ZFP103	G70323CJ G93575MM
Signaling by BMP	Activin receptor type-2A Activin receptor type-2B Anti-Muellerian hormone type-2 receptor Bone morphogenetic protein 10 Bone morphogenetic protein 2 Bone morphogenetic protein receptor type-1A Bone morphogenetic protein receptor type-1B Bone morphogenetic protein receptor type-2 Cerberus Chordin-like protein 1 E3 ubiquitin-protein ligase SMURF1 E3 ubiquitin-protein ligase SMURF2 Follistatin-related protein 1 Gremlin-2 Growth/differentiation factor 2 Inhibin alpha chain Inhibin beta A chain Mothers against decapentaplegic homolog 1 Mothers against decapentaplegic homolog 4 Mothers against decapentaplegic homolog 5 Mothers against decapentaplegic homolog 6 Mothers against decapentaplegic homolog 7 Mothers against decapentaplegic homolog 9 Muellerian-inhibiting factor Noggin Serine/threonine-protein kinase receptor R3 Ski oncogene Transforming growth factor beta receptor type 3 Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D3 Zinc finger FYVE domain-containing protein 16	O00238 O15105 O15198 O43541 O95393 O95813 P03971 P05111 P08476 P12643 P12755 P27037 P36894 P37023 P51668 P61077 Q03167 Q12841 Q13253 Q13485 Q13705 Q13873 Q15797 Q16671 Q7Z3T8 Q99717 Q9BU40 Q9H772 Q9HAU4 Q9HCE7 Q9UK05	ACVR2 ACVR2A ACVR2B ACVRL1 ACVRLK1 ACVRLK3 ALK1 ALK3 AMH AMHR AMHR2 BMP10 BMP2 BMP2A BMP9 BMPR1A BMPR1B BMPR2 BSP1 CER1 CHRDL1 CKTSF1B2 DAND3 DAND4 DPC4 FRP FSTL1 GDF2 GREM2 INHA INHBA KIAA0305 KIAA1625 MADH1 MADH4 MADH5 MADH6 MADH7 MADH8 MADH9 MADR1 MIF MISR2 NOG NRLN1 PPH1 PRDC SFT SKI SMAD1 SMAD4 SMAD5 SMAD6 SMAD7 SMAD8 SMAD9 SMURF1 SMURF2 TGFBR3 UBC5A UBC5C UBCH5 UBCH5A UBCH5C UBE2D1 UBE2D3 ZFYVE16
Signal regulatory protein family interactions	FYN-binding protein 1 Focal adhesion kinase 1 Leukocyte surface antigen CD47 Protein-tyrosine kinase 2-beta Signal-regulatory protein beta-1 Signal-regulatory protein gamma Src kinase-associated phosphoprotein 2 TYRO protein tyrosine kinase-binding protein Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6 Tyrosine-protein phosphatase non-receptor type substrate 1	O00241 O15117 O43914 O75563 P29350 P78324 Q05397 Q06124 Q08722 Q14289 Q9P1W8	BIT CD47 DAP12 FAK FAK1 FAK2 FYB FYB1 HCP KARAP MER6 MFR MYD1 PRAP PTK2 PTK2B PTP1C PTP2C PTPN11 PTPN6 PTPNS1 PYK2 RA70 RAFTK SAPS SCAP2 SHPS1 SHPTP2 SIRP SIRPA SIRPB1 SIRPB2 SIRPG SKAP2 SKAP55R SLAP130 TYROBP
Detoxification of Reactive Oxygen Species	Aquaporin-8 Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] Catalase Copper chaperone for superoxide dismutase Copper transport protein ATOX1 Copper-transporting ATPase 1 Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytochrome c ERO1-like protein alpha Epididymal secretory glutathione peroxidase Extracellular superoxide dismutase [Cu-Zn] Glutathione S-transferase P Glutathione peroxidase 1 Glutathione peroxidase 2 Glutathione peroxidase 3 Glutathione peroxidase 6 Glutathione peroxidase 7 NADPH oxidase 4 NADPH oxidase 5 Neutrophil cytosol factor 1 Neutrophil cytosol factor 2 Neutrophil cytosol factor 4 Peroxiredoxin-1 Peroxiredoxin-2 Peroxiredoxin-6 Probable glutathione peroxidase 8 Protein disulfide-isomerase Superoxide dismutase [Cu-Zn] Superoxide dismutase [Mn], mitochondrial Thioredoxin reductase 1, cytoplasmic Thioredoxin reductase 2, mitochondrial Thioredoxin, mitochondrial Thioredoxin-dependent peroxide reductase, mitochondrial Thioredoxin	O00244 O14618 O75715 O94778 P00441 P04040 P04179 P04839 P07203 P07237 P08294 P09211 P10599 P13498 P14598 P18283 P19878 P22352 P30041 P30048 P32119 P50583 P59796 P99999 Q04656 Q06830 Q15080 Q16881 Q8TED1 Q96HE7 Q96PH1 Q96SL4 Q99757 Q9NNW7 Q9NPH5	AOP1 AOP2 APAH1 AQP8 ATOX1 ATP7A CAT CCS CYBA CYBB CYC CYCS ERBA2L ERO1A ERO1L FAEES3 GPX1 GPX2 GPX3 GPX5 GPX6 GPX7 GPX8 GPXP GRIM12 GST3 GSTP1 HAH1 KDRF KIAA0106 KIAA1652 MC1 MNK NCF1 NCF2 NCF4 NKEFB NOX2 NOX4 NOX5 NOXA2 NOXO2 NUDT2 P4HB P67PHOX PAGA PAGB PDI PDIA1 PO4DB PRDX1 PRDX2 PRDX3 PRDX6 RENOX SH3PXD1A SH3PXD4 SOD1 SOD2 SOD3 TDPX1 TDPX2 TRDX TRX TRX1 TRX2 TRXR2 TXN TXN2 TXNRD1 TXNRD2
Ion influx/efflux at host-pathogen interface	Copper transport protein ATOX1 Copper-transporting ATPase 1 Natural resistance-associated macrophage protein 1 PDZ domain-containing protein 11	O00244 P49279 Q04656 Q5EBL8	AIPP1 ATOX1 ATP7A HAH1 LSH MC1 MNK NRAMP NRAMP1 PDZD11 PDZK11 PISP SLC11A1
Thrombin signalling through proteinase activated receptors (PARs)	Beta-arrestin-1 Beta-arrestin-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-12 Guanine nucleotide-binding protein subunit alpha-13 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha-15 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Proteinase-activated receptor 1 Proteinase-activated receptor 3 Proteinase-activated receptor 4 Prothrombin	O00254 O14610 O14775 O60262 O95837 P00734 P16520 P25116 P27361 P28482 P29992 P30679 P32121 P49407 P50148 P50150 P50151 P59768 P61952 P62873 P62879 P63211 P63215 P63218 Q03113 Q14344 Q96RI0 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	ARB2 ARR1 ARR2 ARRB1 ARRB2 CF2R ERK1 ERK2 F2 F2R F2RL2 F2RL3 GA11 GAQ GNA11 GNA12 GNA13 GNA14 GNA15 GNA16 GNAQ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 MAPK1 MAPK3 PAR1 PAR3 PAR4 PRKM1 PRKM2 PRKM3 TR
Regulation of IGF Activity by IGFBP	72 kDa type IV collagenase Albumin Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Alpha-1-antitrypsin Alpha-2-HS-glycoprotein Alpha-fetoprotein Ameloblastin Amelogenin, X isoform Amelotin Amyloid beta precursor like protein 2 Amyloid-beta precursor protein Anoctamin-8 Antithrombin-III Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-V Apolipoprotein B-100 Apolipoprotein E Apolipoprotein L1 BPI fold-containing family B member 2 Bone morphogenetic protein 15 Bone morphogenetic protein 4 CCN family member 1 Cadherin-2 Calumenin Cathepsin G Ceruloplasmin Chordin-like protein 1 Coagulation factor V Complement C3 Complement C4-A Cystatin-C Cytoskeleton-associated protein 4 Dentin matrix acidic phosphoprotein 1 Disintegrin and metalloproteinase domain-containing protein 10 DnaJ homolog subfamily C member 3 Enamelin Endoplasmin Extracellular serine/threonine protein kinase FAM20C Fibrillin-1 Fibrinogen alpha chain Fibrinogen gamma chain Fibroblast growth factor 23 Fibronectin Follistatin-related protein 1 Follistatin-related protein 3 Galectin-1 Glucosidase 2 subunit beta Glypican-3 Golgi membrane protein 1 Granzyme H Growth arrest-specific protein 6 Heparin cofactor 2 Insulin-like growth factor I Insulin-like growth factor II Insulin-like growth factor-binding protein 1 Insulin-like growth factor-binding protein 2 Insulin-like growth factor-binding protein 3 Insulin-like growth factor-binding protein 4 Insulin-like growth factor-binding protein 5 Insulin-like growth factor-binding protein 6 Insulin-like growth factor-binding protein 7 Insulin-like growth factor-binding protein complex acid labile subunit Inter-alpha-trypsin inhibitor heavy chain H2 Interleukin-6 Interstitial collagenase Kallikrein-13 Kallikrein-1 Kallikrein-2 Kinectin Kininogen-1 Lactadherin Laminin subunit beta-1 Laminin subunit beta-2 Laminin subunit gamma-1 Latent-transforming growth factor beta-binding protein 1 Macrophage colony-stimulating factor 1 Matrilin-3 Matrix extracellular phosphoglycoprotein Matrix remodeling-associated protein 8 Melanotransferrin Membrane-bound transcription factor site-1 protease Menin Mesothelin Metalloproteinase inhibitor 1 Neurosecretory protein VGF Nucleobindin-1 Osteopontin Palmitoleoyl-protein carboxylesterase NOTUM Pappalysin-1 Pappalysin-2 Patatin-like phospholipase domain-containing protein 2 Plasma alpha-L-fucosidase Plasminogen Proenkephalin-A Proprotein convertase subtilisin/kexin type 9 Prostate-specific antigen Protein Z-dependent protease inhibitor Protein disulfide-isomerase A6 Protein disulfide-isomerase Protein eva-1 homolog A Protein shisa-5 Prothrombin Pseudokinase FAM20A Reticulocalbin-1 SPARC-like protein 1 Sarcoplasmic reticulum histidine-rich calcium-binding protein Secreted phosphoprotein 24 Secretogranin-1 Secretogranin-2 Secretogranin-3 Serine protease 23 Serotransferrin Stanniocalcin-2 Sulfhydryl oxidase 1 Syndecan-2 Tenascin Trans-Golgi network integral membrane protein 2 Transmembrane protein 132A Transport and Golgi organization protein 1 homolog Versican core protein Vitamin K-dependent protein C Wolframin von Willebrand factor A domain-containing protein 1	O00255 O00391 O00622 O14672 O14791 O15232 O15240 O43493 O43852 O76024 O76061 O95084 O95633 O95972 P00450 P00734 P00747 P01008 P01009 P01024 P01033 P01034 P01042 P01210 P01344 P02647 P02649 P02652 P02671 P02679 P02751 P02765 P02768 P02771 P02787 P03956 P04070 P04114 P05019 P05060 P05067 P05231 P05546 P06870 P07237 P07288 P07942 P08253 P08311 P08582 P08833 P09382 P09603 P0C0L4 P10451 P11047 P12259 P12644 P13521 P13611 P14314 P14625 P17936 P18065 P19022 P19823 P20151 P20718 P22692 P23327 P24592 P24593 P24821 P34741 P35555 P35858 P51654 P55268 Q02818 Q06481 Q07065 Q08431 Q12841 Q13103 Q13217 Q13219 Q13316 Q13421 Q14393 Q14515 Q14703 Q14766 Q15084 Q15293 Q16270 Q24JP5 Q5JRA6 Q6P988 Q6PCB0 Q6Q788 Q6UX39 Q86UP2 Q8IXL6 Q8N114 Q8N4F0 Q8NBJ4 Q8NBP7 Q8WXD2 Q96AD5 Q96MK3 Q99217 Q9BRK3 Q9BTY2 Q9BU40 Q9BXP8 Q9GZV9 Q9H8M9 Q9HCE9 Q9NP70 Q9NQ76 Q9NRM1 Q9UK55 Q9UKR3 Q9UM21	A4 AAT AD1 ADAM10 AFP AHSG ALB ALS AMBN AMELX AMG AMGX AMTN ANO8 APLP2 APOA1 APOA2 APOA5 APOB APOE APOL APOL1 APP APPL2 APS AT3 ATGL AXLLG BDK BMP15 BMP2B BMP4 BNSP BP2 BPIFB2 BPIL1 C20orf184 C3 C4A C9orf155 CALU CCN1 CDH2 CDHN CG1 CGL2 CHGB CHGC CHRDL1 CKAP4 CLG CLG4A CLGI CO4 CP CPAMD1 CPAMD2 CSF1 CSPG2 CST3 CTSG CTSGL2 CYR61 DMP1 DMP4 DNAJC3 DVR4 ENAM ERBA2L ERP5 EVA1A F2 F5 FAM176A FAM20A FAM20C FBN FBN1 FETUA FGA FGF23 FGG FLRG FN FN1 FRP FSTL1 FSTL3 FUCA2 G19P1 GAS6 GDF9B GIG1 GOLM1 GOLPH2 GPC3 GRP94 GZMH HCF2 HCP HPAFP HRC HSP90B1 HSPA5BP1 HSPC4 HSPG1 HXB HYPF IBP1 IBP2 IBP3 IBP4 IBP5 IBP6 IFNB2 IGF1 IGF2 IGFALS IGFBP1 IGFBP10 IGFBP2 IGFBP3 IGFBP4 IGFBP5 IGFBP6 IGFBP7 IGHEP2 IL6 ITIH2 KIAA0004 KIAA0091 KIAA0268 KIAA1583 KIAA1623 KLK1 KLK13 KLK2 KLK3 KLKL4 KNG KNG1 KTN1 KUZ LAMB1 LAMB2 LAMC1 LAMS LGALS1 LPLUNC2 LTBP1 MAC25 MADM MAP97 MATN3 MBTPS1 MELTF MEN1 MEPE MFGE8 MFI2 MGAT4A MIA3 MMP1 MMP2 MPF MSLN MXRA8 NARC1 NCAD NOTUM NRLN1 NUC NUCB1 OCI5 OPN P4HB P5 P58IPK PAPPA PAPPA2 PCSK9 PDI PDIA1 PDIA6 PENK PI PLAC3 PLG PNPLA2 PO4DB PRKCSH PRKRI PROC PRSS23 PSF QSCN6 QSOX1 RAP3 RCN RCN1 S1P SCG1 SCG2 SCG3 SCOTIN SDC2 SERPINA1 SERPINA10 SERPINC1 SERPIND1 SHISA5 SKI1 SPARCL1 SPP1 SPP2 SPP24 STC2 TANGO TF TGN46 TGN51 TGOLN2 TIMP TIMP1 TMEM132A TMEM166 TMEM16H TNC TRA1 TXNDC7 VCAN VGF VWA1 WFS1 ZPI ZSIG13
Post-translational protein phosphorylation	Albumin Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Alpha-1-antitrypsin Alpha-2-HS-glycoprotein Alpha-fetoprotein Ameloblastin Amelogenin, X isoform Amelotin Amyloid beta precursor like protein 2 Amyloid-beta precursor protein Anoctamin-8 Antithrombin-III Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-V Apolipoprotein B-100 Apolipoprotein E Apolipoprotein L1 BPI fold-containing family B member 2 Bone morphogenetic protein 15 Bone morphogenetic protein 4 CCN family member 1 Cadherin-2 Calumenin Ceruloplasmin Chordin-like protein 1 Coagulation factor V Complement C3 Complement C4-A Cystatin-C Cytoskeleton-associated protein 4 Dentin matrix acidic phosphoprotein 1 Disintegrin and metalloproteinase domain-containing protein 10 DnaJ homolog subfamily C member 3 Enamelin Endoplasmin Extracellular serine/threonine protein kinase FAM20C Fibrillin-1 Fibrinogen alpha chain Fibrinogen gamma chain Fibroblast growth factor 23 Fibronectin Follistatin-related protein 1 Follistatin-related protein 3 Galectin-1 Glucosidase 2 subunit beta Glypican-3 Golgi membrane protein 1 Growth arrest-specific protein 6 Heparin cofactor 2 Insulin-like growth factor-binding protein 1 Insulin-like growth factor-binding protein 3 Insulin-like growth factor-binding protein 4 Insulin-like growth factor-binding protein 5 Insulin-like growth factor-binding protein 7 Inter-alpha-trypsin inhibitor heavy chain H2 Interleukin-6 Kinectin Kininogen-1 Lactadherin Laminin subunit beta-1 Laminin subunit beta-2 Laminin subunit gamma-1 Latent-transforming growth factor beta-binding protein 1 Macrophage colony-stimulating factor 1 Matrilin-3 Matrix extracellular phosphoglycoprotein Matrix remodeling-associated protein 8 Melanotransferrin Membrane-bound transcription factor site-1 protease Menin Mesothelin Metalloproteinase inhibitor 1 Neurosecretory protein VGF Nucleobindin-1 Osteopontin Palmitoleoyl-protein carboxylesterase NOTUM Patatin-like phospholipase domain-containing protein 2 Plasma alpha-L-fucosidase Proenkephalin-A Proprotein convertase subtilisin/kexin type 9 Protein Z-dependent protease inhibitor Protein disulfide-isomerase A6 Protein disulfide-isomerase Protein eva-1 homolog A Protein shisa-5 Pseudokinase FAM20A Reticulocalbin-1 SPARC-like protein 1 Sarcoplasmic reticulum histidine-rich calcium-binding protein Secreted phosphoprotein 24 Secretogranin-1 Secretogranin-2 Secretogranin-3 Serine protease 23 Serotransferrin Stanniocalcin-2 Sulfhydryl oxidase 1 Syndecan-2 Tenascin Trans-Golgi network integral membrane protein 2 Transmembrane protein 132A Transport and Golgi organization protein 1 homolog Versican core protein Vitamin K-dependent protein C Wolframin von Willebrand factor A domain-containing protein 1	O00255 O00391 O00622 O14672 O14791 O15232 O15240 O43493 O43852 O76024 O76061 O95084 O95633 O95972 P00450 P01008 P01009 P01024 P01033 P01034 P01042 P01210 P02647 P02649 P02652 P02671 P02679 P02751 P02765 P02768 P02771 P02787 P04070 P04114 P05060 P05067 P05231 P05546 P07237 P07942 P08582 P08833 P09382 P09603 P0C0L4 P10451 P11047 P12259 P12644 P13521 P13611 P14314 P14625 P17936 P19022 P19823 P22692 P23327 P24593 P24821 P34741 P35555 P51654 P55268 Q02818 Q06481 Q07065 Q08431 Q12841 Q13103 Q13217 Q13316 Q13421 Q14393 Q14515 Q14703 Q14766 Q15084 Q15293 Q16270 Q24JP5 Q5JRA6 Q6P988 Q6PCB0 Q6Q788 Q6UX39 Q86UP2 Q8IXL6 Q8N114 Q8N4F0 Q8NBJ4 Q8NBP7 Q8WXD2 Q96AD5 Q96MK3 Q99217 Q9BRK3 Q9BTY2 Q9BU40 Q9GZV9 Q9H8M9 Q9HCE9 Q9NP70 Q9NQ76 Q9NRM1 Q9UK55 Q9UM21	A4 AAT AD1 ADAM10 AFP AHSG ALB AMBN AMELX AMG AMGX AMTN ANO8 APLP2 APOA1 APOA2 APOA5 APOB APOE APOL APOL1 APP APPL2 AT3 ATGL AXLLG BDK BMP15 BMP2B BMP4 BNSP BPIFB2 BPIL1 C20orf184 C3 C4A C9orf155 CALU CCN1 CDH2 CDHN CG1 CHGB CHGC CHRDL1 CKAP4 CLGI CO4 CP CPAMD1 CPAMD2 CSF1 CSPG2 CST3 CYR61 DMP1 DMP4 DNAJC3 DVR4 ENAM ERBA2L ERP5 EVA1A F5 FAM176A FAM20A FAM20C FBN FBN1 FETUA FGA FGF23 FGG FLRG FN FN1 FRP FSTL1 FSTL3 FUCA2 G19P1 GAS6 GDF9B GIG1 GOLM1 GOLPH2 GPC3 GRP94 HCF2 HCP HPAFP HRC HSP90B1 HSPA5BP1 HSPC4 HSPG1 HXB HYPF IBP1 IBP3 IBP4 IBP5 IFNB2 IGFBP1 IGFBP10 IGFBP3 IGFBP4 IGFBP5 IGFBP7 IGHEP2 IL6 ITIH2 KIAA0004 KIAA0091 KIAA0268 KIAA1583 KIAA1623 KNG KNG1 KTN1 KUZ LAMB1 LAMB2 LAMC1 LAMS LGALS1 LPLUNC2 LTBP1 MAC25 MADM MAP97 MATN3 MBTPS1 MELTF MEN1 MEPE MFGE8 MFI2 MGAT4A MIA3 MPF MSLN MXRA8 NARC1 NCAD NOTUM NRLN1 NUC NUCB1 OCI5 OPN P4HB P5 P58IPK PCSK9 PDI PDIA1 PDIA6 PENK PI PNPLA2 PO4DB PRKCSH PRKRI PROC PRSS23 PSF QSCN6 QSOX1 RAP3 RCN RCN1 S1P SCG1 SCG2 SCG3 SCOTIN SDC2 SERPINA1 SERPINA10 SERPINC1 SERPIND1 SHISA5 SKI1 SPARCL1 SPP1 SPP2 SPP24 STC2 TANGO TF TGN46 TGN51 TGOLN2 TIMP TIMP1 TMEM132A TMEM166 TMEM16H TNC TRA1 TXNDC7 VCAN VGF VWA1 WFS1 ZPI ZSIG13
Formation of the beta-catenin:TCF transactivating complex	B-cell CLL/lymphoma 9 protein B-cell CLL/lymphoma 9-like protein CREB-binding protein Catenin beta-1 Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.1t Histone H3.2 Histone H3.3 Histone H4 Histone acetyltransferase KAT5 Histone acetyltransferase p300 Histone deacetylase 1 Histone-lysine N-methyltransferase 2D Lymphoid enhancer-binding factor 1 Menin Parafibromin Pygopus homolog 1 Pygopus homolog 2 RNA polymerase-associated protein LEO1 Retinoblastoma-binding protein 5 RuvB-like 1 Set1/Ash2 histone methyltransferase complex subunit ASH2 Telomerase reverse transcriptase Transcription activator BRG1 Transcription factor 7-like 1 Transcription factor 7-like 2 Transcription factor 7 Transducin-like enhancer protein 1 Transducin-like enhancer protein 2 Transducin-like enhancer protein 3 Transducin-like enhancer protein 4 Transformation/transcription domain-associated protein	O00255 O00512 O14686 O14746 O60814 P04908 P06899 P0C5Y9 P16104 P20671 P23527 P33778 P35222 P36402 P51532 P57053 P58876 P62805 P62807 P68431 P84243 Q04724 Q04725 Q04726 Q04727 Q09472 Q13547 Q15291 Q16695 Q16777 Q16778 Q6FI13 Q6P1J9 Q71DI3 Q71UI9 Q86UU0 Q8N257 Q8WVC0 Q92793 Q92993 Q93077 Q93079 Q96A08 Q99877 Q99878 Q99879 Q99880 Q9BRQ0 Q9BTM1 Q9HCS4 Q9NQB0 Q9UBL3 Q9UJU2 Q9Y265 Q9Y3Y4 Q9Y4A5	ALR ASH2L ASH2L1 BAF190A BCL9 BCL9L BRG1 C1orf28 CBP CDC73 CREBBP CTNNB CTNNB1 DLNB11 EP300 EST2 GRG4 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3-4 H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H3FT H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HDAC1 HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST3H3 HIST4H4 HRPT2 HTATIP INO80H KAT5 KIAA1261 KIAA1547 KMT2D LEF1 LEO1 MEN1 MLL2 MLL4 NMP238 P300 PAF400 PYGO1 PYGO2 RBBP5 RBQ3 RDL RPD3L1 RUVBL1 SCG2 SMARCA4 SNF2B SNF2L4 TCF1 TCF3 TCF4 TCF7 TCF7L1 TCF7L2 TCS1 TERT TIP49 TIP49A TIP60 TLE1 TLE2 TLE3 TLE4 TRRAP TRT TSH2B
Deactivation of the beta-catenin transactivating complex	14-3-3 protein zeta/delta Adenomatous polyposis coli protein B-cell CLL/lymphoma 9 protein B-cell CLL/lymphoma 9-like protein Beta-catenin-interacting protein 1 C-terminal-binding protein 1 Catenin beta-1 Chromodomain-helicase-DNA-binding protein 8 E3 ubiquitin-protein ligase XIAP Exportin-1 F-box/WD repeat-containing protein 1A Histone deacetylase 1 Histone-lysine N-methyltransferase 2D Lymphoid enhancer-binding factor 1 Menin Polyubiquitin-B Polyubiquitin-C Protein chibby homolog 1 Pygopus homolog 1 Pygopus homolog 2 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase Retinoblastoma-binding protein 5 Set1/Ash2 histone methyltransferase complex subunit ASH2 Sex-determining region Y protein Transcription factor 7-like 1 Transcription factor 7-like 2 Transcription factor 7 Transcription factor SOX-13 Transcription factor SOX-17 Transcription factor SOX-2 Transcription factor SOX-3 Transcription factor SOX-4 Transcription factor SOX-6 Transcription factor SOX-7 Transcription factor SOX-9 Transducin-like enhancer protein 1 Transducin-like enhancer protein 2 Transducin-like enhancer protein 3 Transducin-like enhancer protein 4 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00255 O00512 O14686 O14980 P0CG47 P0CG48 P25054 P31749 P31751 P35222 P35712 P36402 P41225 P48431 P48436 P62979 P62987 P63104 P98170 Q04724 Q04725 Q04726 Q04727 Q05066 Q06945 Q13363 Q13547 Q15291 Q86UU0 Q9BRQ0 Q9BT81 Q9H6I2 Q9HCK8 Q9HCS4 Q9NQB0 Q9NSA3 Q9UBL3 Q9UJU2 Q9UN79 Q9Y297 Q9Y3M2 Q9Y3Y4	AKT1 AKT2 ALR APC API3 ARB1 ASH2L ASH2L1 BCL9 BCL9L BIRC4 BTRC BTRCP C22orf2 CBY CBY1 CHD8 CRM1 CTBP CTBP1 CTNNB CTNNB1 CTNNBIP1 DLNB11 DP2.5 FBW1A FBXW1A GRG4 HDAC1 HELSNF1 IAP3 ICAT KIAA1261 KIAA1547 KIAA1564 KMT2D LEF1 MEN1 MLL2 MLL4 PGEA1 PKB PYGO1 PYGO2 RAC RBBP5 RBQ3 RPD3L1 RPS27A SCG2 SOX13 SOX17 SOX2 SOX3 SOX4 SOX6 SOX7 SOX9 SRY TCF1 TCF3 TCF4 TCF7 TCF7L1 TCF7L2 TDF TLE1 TLE2 TLE3 TLE4 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 XIAP XPO1 YWHAZ
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	Collagen alpha-2(I) chain Cyclin-C Cyclin-K Cyclin-T1 Cyclin-T2 Cyclin-dependent kinase 4 inhibitor B Cyclin-dependent kinase 8 Cyclin-dependent kinase 9 E3 ubiquitin-protein ligase Arkadia Furin Histone acetyltransferase p300 Histone deacetylase 1 Homeobox protein TGIF1 Homeobox protein TGIF2 Menin Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Mothers against decapentaplegic homolog 7 Myc proto-oncogene protein Plasminogen activator inhibitor 1 Polyubiquitin-B Polyubiquitin-C Retinoblastoma-like protein 1 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F4 Transcription factor E2F5 Transcription factor JunB Transcription factor Sp1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein WW domain-containing transcription regulator protein 1 Y-box-binding protein 1	O00255 O15105 O60563 O60583 O75909 P01106 P05121 P08047 P08123 P09958 P0CG47 P0CG48 P17275 P24863 P27361 P28482 P28749 P42772 P49336 P50750 P62979 P62987 P67809 P84022 Q09472 Q13485 Q13547 Q14186 Q14188 Q15329 Q15583 Q15796 Q16254 Q6ZNA4 Q9GZN2 Q9GZV5	BHLHE39 CCNC CCNK CCNT1 CCNT2 CDC2L4 CDK8 CDK9 CDKN2B COL1A2 CPR4 DP1 DP2 DPC4 E2F4 E2F5 EP300 ERK1 ERK2 FUR FURIN HDAC1 JUNB MADH2 MADH3 MADH4 MADH7 MADH8 MADR2 MAPK1 MAPK3 MEN1 MTS2 MYC NSEP1 P300 PACE PAI1 PCSK3 PLANH1 PRKM1 PRKM2 PRKM3 RBL1 RNF111 RPD3L1 RPS27A SCG2 SERPINE1 SMAD2 SMAD3 SMAD4 SMAD7 SP1 TAK TAZ TFDP1 TFDP2 TGIF TGIF1 TGIF2 TSFP1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WWTR1 YB1 YBX1
RHO GTPases activate IQGAPs	CAP-Gly domain-containing linker protein 1 Cadherin-1 Calmodulin-1 Catenin alpha-1 Catenin beta-1 Cell division control protein 42 homolog Menin Ras GTPase-activating-like protein IQGAP1 Ras GTPase-activating-like protein IQGAP2 Ras GTPase-activating-like protein IQGAP3 Ras-related C3 botulinum toxin substrate 1	O00255 P0DP23 P12830 P30622 P35221 P35222 P46940 P60953 P63000 Q13576 Q86VI3	CALM CALM1 CAM CAM1 CDC42 CDH1 CDHE CLIP1 CTNNA1 CTNNB CTNNB1 CYLN1 IQGAP1 IQGAP2 IQGAP3 KIAA0051 MEN1 RAC1 RSN SCG2 TC25 UVO
Oxidative Stress Induced Senescence	Cellular tumor antigen p53 Chromobox protein homolog 2 Chromobox protein homolog 6 Chromobox protein homolog 8 Cyclin-dependent kinase 4 inhibitor B Cyclin-dependent kinase 4 inhibitor C Cyclin-dependent kinase 4 inhibitor D Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 Cyclin-dependent kinase inhibitor 2A Dual specificity mitogen-activated protein kinase kinase 3 Dual specificity mitogen-activated protein kinase kinase 4 Dual specificity mitogen-activated protein kinase kinase 6 Dual specificity mitogen-activated protein kinase kinase 7 E3 SUMO-protein ligase CBX4 E3 ubiquitin-protein ligase Mdm2 E3 ubiquitin-protein ligase RING1 E3 ubiquitin-protein ligase RING2 Helicase MOV-10 Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Histone-lysine N-methyltransferase EZH2 Interferon beta Lysine-specific demethylase 6B MAP kinase-activated protein kinase 2 MAP kinase-activated protein kinase 3 MAP kinase-activated protein kinase 5 Misshapen-like kinase 1 Mitogen-activated protein kinase 10 Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 14 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase 8 Mitogen-activated protein kinase 9 Mitogen-activated protein kinase kinase kinase 5 Mitogen-activated protein kinase kinase kinase kinase 4 Polycomb complex protein BMI-1 Polycomb protein EED Polycomb protein SUZ12 Polyhomeotic-like protein 1 Polyhomeotic-like protein 2 Polyhomeotic-like protein 3 Polyubiquitin-B Polyubiquitin-C Protein Mdm4 Protein argonaute-1 Protein argonaute-3 Protein argonaute-4 Protein c-Fos TRAF2 and NCK-interacting protein kinase Thioredoxin Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor E2F2 Transcription factor E2F3 Transcription factor Jun Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein Tumor suppressor ARF Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00257 O00716 O14733 O15054 O15151 O60814 O75530 O95503 O95819 P01100 P01574 P04637 P04908 P05412 P06899 P0C5Y9 P0CG47 P0CG48 P10599 P11802 P16104 P20671 P23527 P27361 P28482 P33778 P35226 P42771 P42772 P42773 P45983 P45984 P45985 P46734 P49137 P52564 P53779 P55273 P57053 P58876 P62805 P62807 P62979 P62987 P68431 P78364 P84243 Q00534 Q00987 Q01094 Q06587 Q09028 Q14186 Q14188 Q14209 Q14781 Q15022 Q15759 Q15910 Q16539 Q16576 Q16644 Q16777 Q16778 Q6FI13 Q71DI3 Q71UI9 Q8IW41 Q8IXK0 Q8N257 Q8N4C8 Q8N726 Q8NDV7 Q8NDX5 Q93077 Q93079 Q96A08 Q99496 Q99683 Q99877 Q99878 Q99879 Q99880 Q9BTM1 Q9H9G7 Q9HC52 Q9HCE1 Q9HCJ0 Q9HCK5 Q9UKE5 Q9UL18 Q9UPQ9	AGO1 AGO3 AGO4 ASK1 B55 BAP1 BMI1 CAGH26 CBX2 CBX4 CBX6 CBX8 CDK4 CDK6 CDKN2 CDKN2A CDKN2B CDKN2C CDKN2D CDKN6 CHET9 CSBP CSBP1 CSBP2 CSPB1 DING DP1 DP2 E2F1 E2F2 E2F3 EDR1 EDR2 EDR3 EED EIF2C1 EIF2C3 EIF2C4 ERK1 ERK2 EZH2 FOS G0S7 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HGK HIPI3 HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 IFB IFNB IFNB1 JJAZ1 JMJD3 JNK1 JNK2 JNK3 JNK3A JNKK1 JNKK2 JUN KDM6B KIAA0075 KIAA0160 KIAA0346 KIAA0551 KIAA0687 KIAA1093 KIAA1460 KIAA1567 KIAA1582 KIAA1631 KMT6 MAP2K3 MAP2K4 MAP2K6 MAP2K7 MAP3K5 MAP4K4 MAP4K6 MAPK1 MAPK10 MAPK11 MAPK14 MAPK3 MAPK8 MAPK9 MAPKAPK2 MAPKAPK3 MAPKAPK5 MAPKKK5 MDM2 MDM4 MDMX MEK3 MEK4 MEK6 MEK7 MEKK5 MINK MINK1 MKK3 MKK4 MKK6 MKK7 MLM MOV10 MTS1 MTS2 MXI2 NIK P53 PC3 PCGF4 PH1 PH2 PH3 PHC1 PHC2 PHC3 PRAK PRKM1 PRKM10 PRKM11 PRKM2 PRKM3 PRKM8 PRKM9 PRKMK3 PRKMK4 PRKMK6 PRKMK7 RBAP46 RBAP48 RBBP3 RBBP4 RBBP7 RC1 RING1 RING1A RING1B RNF1 RNF2 RNF51 RPS27A SAPK1 SAPK1A SAPK1B SAPK1C SAPK2 SAPK2A SAPK2B SEK1 SERK1 SKK1 SKK2 SKK3 SKK4 SUZ12 TFDP1 TFDP2 TNIK TNRC6 TNRC6A TNRC6B TNRC6C TP53 TRDX TRX TRX1 TSH2B TXN UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 YSK2 ZC3
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	AT-rich interactive domain-containing protein 1A AT-rich interactive domain-containing protein 1B AT-rich interactive domain-containing protein 2 Actin-like protein 6A Actin-like protein 6B Autism susceptibility gene 2 protein Casein kinase II subunit alpha' Casein kinase II subunit alpha Casein kinase II subunit beta Chromobox protein homolog 2 Chromobox protein homolog 6 Chromobox protein homolog 8 Core-binding factor subunit beta E3 SUMO-protein ligase CBX4 E3 ubiquitin-protein ligase RING1 E3 ubiquitin-protein ligase RING2 Histone acetyltransferase p300 Homeodomain-interacting protein kinase 2 Polycomb complex protein BMI-1 Polycomb group RING finger protein 5 Polyhomeotic-like protein 1 Polyhomeotic-like protein 2 Polyhomeotic-like protein 3 Probable global transcription activator SNF2L2 Protein polybromo-1 RING1 and YY1-binding protein Runt-related transcription factor 1 SWI/SNF complex subunit SMARCC1 SWI/SNF complex subunit SMARCC2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 Transcription activator BRG1 YY1-associated factor 2	O00257 O14497 O94805 O95503 O96019 P19784 P35226 P51531 P51532 P67870 P68400 P78364 Q01196 Q06587 Q09472 Q12824 Q13951 Q14781 Q68CP9 Q6STE5 Q86SE9 Q86U86 Q8IXK0 Q8IY57 Q8N488 Q8NDX5 Q8NFD5 Q8TAQ2 Q8WXX7 Q92922 Q92925 Q969G3 Q96GM5 Q99496 Q9H2X6 Q9HC52	ACTL6 ACTL6A ACTL6B AML1 ARID1A ARID1B ARID2 AUTS2 BAF155 BAF170 BAF180 BAF190A BAF190B BAF200 BAF250 BAF250A BAF250B BAF47 BAF53 BAF53A BAF53B BAF57 BAF60A BAF60B BAF60C BAP1 BMI1 BRG1 BRM C1orf4 CBFA2 CBFB CBX2 CBX4 CBX6 CBX8 CK2A1 CK2A2 CK2N CSNK2A1 CSNK2A2 CSNK2B DAN15 DEDAF DING EDR1 EDR2 EDR3 EP300 G5A HIPI3 HIPK2 INI1 INO80K KIAA0442 KIAA1235 KIAA1557 OSA1 OSA2 P300 PB1 PBRM1 PC3 PCGF4 PCGF5 PH1 PH2 PH3 PHC1 PHC2 PHC3 RC1 RING1 RING1A RING1B RNF1 RNF159 RNF2 RNF51 RUNX1 RYBP SMARCA2 SMARCA4 SMARCB1 SMARCC1 SMARCC2 SMARCD1 SMARCD2 SMARCD3 SMARCE1 SMARCF1 SNF2A SNF2B SNF2L2 SNF2L4 SNF5L1 YAF2 YEAF1
Regulation of PTEN gene transcription	Atrophin-1 Cellular tumor antigen p53 Chromobox protein homolog 2 Chromobox protein homolog 6 Chromobox protein homolog 8 Chromodomain-helicase-DNA-binding protein 3 Chromodomain-helicase-DNA-binding protein 4 Cyclic AMP-dependent transcription factor ATF-2 E3 SUMO-protein ligase CBX4 E3 ubiquitin-protein ligase RING1 E3 ubiquitin-protein ligase RING2 Early growth response protein 1 GTP-binding protein Rheb Histone deacetylase 1 Histone deacetylase 2 Histone deacetylase 3 Histone deacetylase 5 Histone deacetylase 7 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Histone-lysine N-methyltransferase EZH2 Histone-lysine N-methyltransferase MECOM Lysine-specific histone demethylase 1A Metastasis-associated protein MTA1 Metastasis-associated protein MTA2 Metastasis-associated protein MTA3 Methyl-CpG-binding domain protein 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Neutral amino acid transporter 9 Nuclear receptor subfamily 2 group E member 1 Peroxisome proliferator-activated receptor gamma Polycomb complex protein BMI-1 Polycomb protein EED Polycomb protein SUZ12 Polyhomeotic-like protein 1 Polyhomeotic-like protein 2 Polyhomeotic-like protein 3 RE1-silencing transcription factor REST corepressor 1 Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein A Ras-related GTP-binding protein B Ras-related GTP-binding protein C Ras-related GTP-binding protein D Regulatory-associated protein of mTOR Repressor of RNA polymerase III transcription MAF1 homolog Sal-like protein 4 Serine/threonine-protein kinase mTOR Target of rapamycin complex subunit LST8 Transcription factor Jun Transcriptional repressor p66-alpha Transcriptional repressor p66-beta Zinc finger protein SNAI1 Zinc finger protein SNAI2	O00257 O15379 O43504 O43623 O60341 O75530 O94776 O95503 O95863 O95983 P04637 P05412 P15336 P18146 P27361 P28482 P35226 P37231 P42345 P54259 P78364 Q03112 Q06587 Q09028 Q0VGL1 Q12873 Q13127 Q13330 Q13547 Q14781 Q14839 Q15022 Q15382 Q15910 Q16576 Q5VZM2 Q6IAA8 Q7L523 Q86YP4 Q8IXK0 Q8N122 Q8NBW4 Q8NDX5 Q8WUI4 Q8WXI9 Q92769 Q99496 Q9BTC8 Q9BVC4 Q9H063 Q9HB90 Q9HC52 Q9NQL2 Q9UHA4 Q9UJQ4 Q9UKL0 Q9UQL6 Q9Y2Q5 Q9Y466	AOF2 ATF2 ATN1 BAP1 BMI1 C11orf59 C7orf59 CBX2 CBX4 CBX6 CBX8 CHD3 CHD4 CHET9 CREB2 CREBP1 D12S755E DING DRPLA EDR1 EDR2 EDR3 EED EGR1 ERK1 ERK2 EVI1 EZH2 FRAP FRAP1 FRAP2 GATAD2A GATAD2B GBL HBXIP HDAC1 HDAC2 HDAC3 HDAC5 HDAC7 HDAC7A HIPI3 JJAZ1 JUN KDM1 KDM1A KIAA0071 KIAA0160 KIAA0600 KIAA0601 KIAA1150 KIAA1266 KIAA1303 KMT6 KROX24 LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 LSD1 LST8 MAF1 MAP2K1IP1 MAPBPIP MAPK1 MAPK3 MAPKSP1 MBD3 MDS1 MECOM MLST8 MTA1 MTA1L1 MTA2 MTA3 MTOR NR1C3 NR2E1 NRSF P53 PC3 PCGF4 PDRO PH1 PH2 PH3 PHC1 PHC2 PHC3 PID PPARG PRDM3 PRKM1 PRKM2 PRKM3 RAFT1 RAPT1 RAPTOR RBAP46 RBAP48 RBBP4 RBBP7 RC1 RCOR RCOR1 REST RHEB RHEB2 RING1 RING1A RING1B RNF1 RNF2 RNF51 ROBLD3 RPD3L1 RPTOR RRAGA RRAGB RRAGC RRAGD SALL4 SLC38A9 SLUG SLUGH SNAH SNAI1 SNAI2 SUZ12 TLX TP53 URLC11 XBR XIP ZNF225 ZNF797

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