GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **626 - 650** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol
C6 deamination of adenosine	Double-stranded RNA-specific adenosine deaminase Double-stranded RNA-specific editase 1	P55265 P78563	ADAR ADAR1 ADAR2 ADARB1 DRADA2 DSRAD G1P1 IFI4 RED1
Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1	Dystroglycan 1 Protein O-mannosyl-transferase 1 Protein O-mannosyl-transferase 2	Q14118 Q9UKY4 Q9Y6A1	DAG1 POMT1 POMT2
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA)	Electrogenic sodium bicarbonate cotransporter 1	Q9Y6R1	NBC NBC1 NBCE1 SLC4A4
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2	Cytochrome P450 1A2	P05177	CYP1A2
Cohesin Loading onto Chromatin	Cohesin subunit SA-1 Cohesin subunit SA-2 Double-strand-break repair protein rad21 homolog MAU2 chromatid cohesion factor homolog Nipped-B-like protein Sister chromatid cohesion protein PDS5 homolog A Sister chromatid cohesion protein PDS5 homolog B Structural maintenance of chromosomes protein 1A Structural maintenance of chromosomes protein 3 Wings apart-like protein homolog	O60216 Q14683 Q29RF7 Q6KC79 Q7Z5K2 Q8N3U4 Q8WVM7 Q9NTI5 Q9UQE7 Q9Y6X3	APRIN AS3 BAM BMH CSPG6 DXS423E FOE HR21 IDN3 KIAA0078 KIAA0178 KIAA0261 KIAA0648 KIAA0892 KIAA0979 MAU2 NIPBL NXP1 PDS5 PDS5A PDS5B RAD21 SA1 SA2 SB1.8 SCC1 SCC2 SCC3 SCC4 SMC1 SMC1A SMC1L1 SMC3 SMC3L1 STAG1 STAG2 WAPAL WAPL
rRNA modification in the nucleus and cytosol	18S rRNA aminocarboxypropyltransferase DDB1- and CUL4-associated factor 13 H/ACA ribonucleoprotein complex subunit 1 H/ACA ribonucleoprotein complex subunit 2 H/ACA ribonucleoprotein complex subunit 3 H/ACA ribonucleoprotein complex subunit DKC1 HEAT repeat-containing protein 1 KRR1 small subunit processome component homolog Multifunctional methyltransferase subunit TRM112-like protein NHP2-like protein 1 Nucleolar complex protein 4 homolog Nucleolar protein 11 Nucleolar protein 14 Nucleolar protein 56 Nucleolar protein 58 Nucleolar protein 6 Periodic tryptophan protein 2 homolog Probable 18S rRNA (guanine-N(7))-methyltransferase Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase Probable ATP-dependent RNA helicase DDX47 Probable ATP-dependent RNA helicase DDX49 Probable ATP-dependent RNA helicase DDX52 Probable ATP-dependent RNA helicase DHX37 Probable U3 small nucleolar RNA-associated protein 11 Probable dimethyladenosine transferase Protein RRP5 homolog RNA 3'-terminal phosphate cyclase-like protein RNA cytidine acetyltransferase RNA-binding protein PNO1 Ribosomal RNA processing protein 36 homolog Ribosomal RNA small subunit methyltransferase NEP1 Ribosomal RNA-processing protein 7 homolog A Ribosome biogenesis protein BMS1 homolog Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small subunit processome component 20 homolog Something about silencing protein 10 THUMP domain-containing protein 1 Transducin beta-like protein 3 U3 small nucleolar RNA-associated protein 14 homolog A U3 small nucleolar RNA-associated protein 14 homolog C U3 small nucleolar RNA-associated protein 15 homolog U3 small nucleolar RNA-associated protein 18 homolog U3 small nucleolar RNA-associated protein 25 homolog U3 small nucleolar RNA-associated protein 4 homolog U3 small nucleolar RNA-associated protein 6 homolog U3 small nucleolar RNA-interacting protein 2 U3 small nucleolar ribonucleoprotein protein IMP3 U3 small nucleolar ribonucleoprotein protein IMP4 U3 small nucleolar ribonucleoprotein protein MPP10 WD repeat-containing protein 36 WD repeat-containing protein 3 WD repeat-containing protein 43 WD repeat-containing protein 46 WD repeat-containing protein 75 rRNA 2'-O-methyltransferase fibrillarin rRNA-processing protein FCF1 homolog	O00566 O00567 O15213 O43709 O43818 O60832 O75691 P15880 P22087 P46087 P46781 P55769 P62081 P62263 P62753 P78316 Q12788 Q13601 Q14690 Q14692 Q15061 Q15269 Q5TAP6 Q68CQ4 Q8IWA0 Q8IY37 Q8NI36 Q8TED0 Q92979 Q969X6 Q96EU6 Q96G21 Q9BVI4 Q9BVJ6 Q9H0A0 Q9H0S4 Q9H583 Q9H6R4 Q9H8H0 Q9NPE3 Q9NQZ2 Q9NRX1 Q9NV06 Q9NV31 Q9NX24 Q9NXG2 Q9NY12 Q9NYH9 Q9UI30 Q9UJK0 Q9UNQ2 Q9UNX4 Q9Y2P8 Q9Y2R4 Q9Y2X3 Q9Y324 Q9Y3A2 Q9Y3A4 Q9Y5J1 Q9Y6V7	ALP BAP28 BING4 BMS1 BMS1L BUD23 BXDC4 C14orf111 C15orf12 C16orf42 C17orf40 C1orf107 C2F C4orf9 C6orf11 C6orf153 CIRH1A CRLZ1 DCAF13 DDX37 DDX47 DDX49 DDX52 DEF DHX37 DIEXF DIMT1 DIMT1L DKC1 DRIM EMG1 FBL FCF1 FIB1 FLRN GAR1 HCA66 HEATR1 HRB2 IMP3 IMP4 KIAA0007 KIAA0185 KIAA0187 KIAA0266 KIAA1517 KIAA1709 KIAA1988 KRR1 MERM1 MHAT MPHOSPH10 MPP10 MRPS4 NAT10 NHP2 NHP2L1 NOC4L NOL1 NOL11 NOL14 NOL5 NOL5A NOL6 NOLA1 NOLA2 NOLA3 NOLA4 NOP10 NOP14 NOP2 NOP5 NOP56 NOP58 NSUN1 PDCD11 PNO1 PWP2 PWP2H RCL1 RNAC RNU3IP2 ROK1 RPC2 RPCL1 RPS14 RPS2 RPS4 RPS6 RPS7 RPS9 RRP36 RRP7A RRP9 RTC2 SAS10 SAZD SDCCAG16 SNU13 TBL3 THUMPD1 TRMT112 TSR3 U355K UND313L UTP10 UTP11 UTP11L UTP14A UTP14C UTP15 UTP17 UTP18 UTP20 UTP25 UTP3 UTP4 UTP5 UTP6 WBSCR22 WDR3 WDR36 WDR43 WDR46 WDR50 WDR75 WDSOF1 cPERP-E
Defective MMAA causes MMA, cblA type	Methylmalonic aciduria type A protein, mitochondrial Methylmalonyl-CoA mutase, mitochondrial	P22033 Q8IVH4	MMAA MMUT MUT
Activation of ATR in response to replication stress	ATR-interacting protein Cell cycle checkpoint control protein RAD9A Cell cycle checkpoint control protein RAD9B Cell cycle checkpoint protein RAD17 Cell cycle checkpoint protein RAD1 Cell division control protein 45 homolog Cell division control protein 6 homolog Cell division cycle 7-related protein kinase Checkpoint protein HUS1 Claspin Cyclin-dependent kinase 2 DNA helicase MCM8 DNA replication licensing factor MCM2 DNA replication licensing factor MCM3 DNA replication licensing factor MCM4 DNA replication licensing factor MCM5 DNA replication licensing factor MCM6 DNA replication licensing factor MCM7 M-phase inducer phosphatase 1 M-phase inducer phosphatase 3 Origin recognition complex subunit 1 Origin recognition complex subunit 2 Origin recognition complex subunit 3 Origin recognition complex subunit 4 Origin recognition complex subunit 5 Origin recognition complex subunit 6 Protein DBF4 homolog A Protein MCM10 homolog Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Serine/threonine-protein kinase ATR Serine/threonine-protein kinase Chk1	O00311 O14757 O43913 O43929 O60671 O60921 O75419 O75943 P15927 P24941 P25205 P27694 P30304 P30307 P33991 P33992 P33993 P35244 P35249 P35250 P40937 P40938 P49736 Q13415 Q13416 Q13535 Q14566 Q6WBX8 Q7L590 Q8WXE1 Q99638 Q99741 Q9HAW4 Q9UBD5 Q9UBU7 Q9UJA3 Q9Y5N6	AGS1 ASK ATR ATRIP BM28 C20orf154 CCNL1 CDC18L CDC21 CDC25A CDC25C CDC45 CDC45L CDC45L2 CDC46 CDC47 CDC6 CDC7 CDC7L1 CDCL1 CDK2 CDKN2 CHEK1 CHK1 CLSPN DBF4 DBF4A FRP1 HUS1 KIAA0030 LATHEO MCM10 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MCM8 ORC1 ORC1L ORC2 ORC2L ORC3 ORC3L ORC4 ORC4L ORC5 ORC5L ORC6 ORC6L PARC1 R24L RAD1 RAD17 RAD9A RAD9B REC1 REPA1 REPA2 REPA3 RFC2 RFC3 RFC4 RFC5 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 ZDBF1
Glutathione synthesis and recycling	5-oxoprolinase Cytosolic non-specific dipeptidase Gamma-glutamylcyclotransferase Glutamate--cysteine ligase catalytic subunit Glutamate--cysteine ligase regulatory subunit Glutathione hydrolase 1 proenzyme Glutathione hydrolase 5 proenzyme Glutathione hydrolase 6 Glutathione hydrolase 7 Glutathione synthetase Glutathione-specific gamma-glutamylcyclotransferase 1 Glutathione-specific gamma-glutamylcyclotransferase 2 Putative glutathione hydrolase 3 proenzyme	A6NGU5 O14841 O75223 P19440 P36269 P48506 P48507 P48637 Q6P531 Q8WUX2 Q96KP4 Q9BUX1 Q9UJ14	BOTCH C7orf24 CHAC1 CHAC2 CN2 CNDP2 CPGL CRF21 GCLC GCLM GGCT GGT GGT1 GGT3 GGT3P GGT5 GGT6 GGT7 GGTL3 GGTL5 GGTLA1 GLCL GLCLC GLCLR GSS HEL-S-13 OPLAH PEPA
Ketone body catabolism	Acetyl-CoA acetyltransferase, mitochondrial D-beta-hydroxybutyrate dehydrogenase, mitochondrial Succinyl-CoA Succinyl-CoA	P24752 P55809 Q02338 Q9BYC2	ACAT ACAT1 BDH BDH1 MAT OXCT OXCT1 OXCT2 SCOT SDR9C1
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)	Complement receptor type 1 Core-binding factor subunit beta Cytotoxic T-lymphocyte protein 4 Forkhead box protein P3 Interferon gamma Interleukin-2 receptor subunit alpha Interleukin-2 Nuclear factor of activated T-cells, cytoplasmic 2 Runt-related transcription factor 1 Tumor necrosis factor receptor superfamily member 18	P01579 P01589 P16410 P17927 P60568 Q01196 Q13469 Q13951 Q9BZS1 Q9Y5U5	AITR AML1 C3BR CBFA2 CBFB CD152 CR1 CTLA4 FOXP3 GITR IFNG IL2 IL2RA IPEX NFAT1 NFATC2 NFATP RUNX1 TNFRSF18
Defective ABCA1 causes TGD	Apolipoprotein A-I Phospholipid-transporting ATPase ABCA1	O95477 P02647	ABC1 ABCA1 APOA1 CERP
Surfactant metabolism	Adenosine deaminase 2 Adenosine receptor A2a Adenosine receptor A2b Adhesion G protein-coupled receptor F5 Alpha-2A adrenergic receptor Alpha-2C adrenergic receptor Cytokine receptor common subunit beta Cytoskeleton-associated protein 4 Deleted in malignant brain tumors 1 protein Granulocyte-macrophage colony-stimulating factor receptor subunit alpha LIM and cysteine-rich domains protein 1 Napsin-A P2Y purinoceptor 2 Palmitoyltransferase ZDHHC2 Pepsin A-3 Pepsin A-4 Pepsin A-5 Phospholipid-transporting ATPase ABCA3 Pro-cathepsin H Pulmonary surfactant-associated protein A1 Pulmonary surfactant-associated protein A2 Pulmonary surfactant-associated protein B Pulmonary surfactant-associated protein D Sodium-dependent phosphate transport protein 2A Sodium-dependent phosphate transport protein 2B Surfactant protein C Surfactant-associated protein 3 Thyroid transcription factor 1-associated protein 26 Transcription factor GATA-6 Transcription termination factor 1	O95436 O96009 P07988 P08913 P09668 P0C7M3 P0DJD7 P0DJD8 P0DJD9 P11686 P15509 P18825 P29274 P29275 P32927 P35247 P41231 Q06495 Q07065 Q15361 Q8IWL1 Q8IWL2 Q8IZF2 Q92908 Q99758 Q9NZK5 Q9NZU5 Q9P031 Q9UGM3 Q9UIJ5	ABC3 ABCA3 ADA2 ADGF ADGRF5 ADORA2 ADORA2A ADORA2B ADRA2A ADRA2C ADRA2L2 ADRA2R ADRA2RL2 ADRAR BR22 CCDC59 CECR1 CKAP4 COLEC4 COLEC5 COLEC7 CPSB CSF2R CSF2RA CSF2RB CSF2RY CTSH DMBT1 GATA6 GP340 GPR116 IDGFL IL3RB IL5RB KIAA0758 LMCD1 NAP1 NAPA NAPSA NPT2 P2RU1 P2RY2 PGA3 PGA4 PGA5 PSAP PSPD REAM REC SFTA3 SFTP1 SFTP2 SFTP3 SFTP4 SFTPA SFTPA1 SFTPA1B SFTPA2 SFTPA2B SFTPB SFTPC SFTPD SFTPH SLC17A2 SLC34A1 SLC34A2 TAP26 TTF1 ZDHHC2 ZNF372
Defective CFTR causes cystic fibrosis	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cystic fibrosis transmembrane conductance regulator Derlin-1 Derlin-2 Derlin-3 E3 ubiquitin-protein ligase RNF185 E3 ubiquitin-protein ligase RNF5 Endoplasmic reticulum lectin 1 Erlin-1 Erlin-2 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein OS-9 Protein sel-1 homolog 1 Transitional endoplasmic reticulum ATPase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O43242 O75477 O75832 O94905 P0CG47 P0CG48 P13569 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P55072 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q06323 Q13200 Q13438 Q14997 Q15008 Q16401 Q8TAA3 Q92530 Q96DZ1 Q96GF1 Q96Q80 Q99436 Q99460 Q99942 Q9BUN8 Q9GZP9 Q9UBV2 Q9UL46 Q9UNM6	ABCC7 C10orf69 C22orf14 C2orf30 C7orf76 C8orf2 CFTR DER1 DER2 DER3 DERL1 DERL2 DERL3 DSS1 ERLEC1 ERLIN1 ERLIN2 FLANA G16 HC2 HC3 HC8 HC9 HEL-220 HEL-S-70 HSPC IFI5111 KE04 KEO4 KIAA0072 KIAA0077 KIAA0107 LLN2 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NG2 NU OS9 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RING10 RING12 RMA1 RNF185 RNF5 RPS27A SEL1L SEM1 SHFDG1 SHFM1 SPFH1 SPFH2 SUG1 SUG2 TBP1 TBP7 TRAP2 TSA305 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VCP X XTP3TPB Y Y2 Z
Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum)	Hephaestin Solute carrier family 40 member 1	Q9BQS7 Q9NP59	FPN FPN1 HEPH IREG1 KIAA0698 SLC11A3 SLC40A1
MET interacts with TNS proteins	Hepatocyte growth factor receptor Hepatocyte growth factor Integrin beta-1 Tensin-3 Tensin-4	P05556 P08581 P14210 Q68CZ2 Q8IZW8	CTEN FNRB HGF HPTA ITGB1 MDF2 MET MSK12 TEM6 TENS1 TNS3 TNS4 TPP
PI-3K cascade:FGFR4	Beta-klotho Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 19 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 GRB2-associated-binding protein 1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Tyrosine-protein phosphatase non-receptor type 11	O43320 O76093 O95750 P05230 P08620 P09038 P10767 P22455 P27986 P31371 P42336 Q06124 Q13480 Q86Z14 Q8WU20 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF9 FGFA FGFB FGFR4 FRS2 GAB1 GRB1 HST HST2 HSTF1 HSTF2 HYPF JTK2 KLB KS3 PIK3CA PIK3R1 PTP2C PTPN11 SHPTP2 TKF
Role of second messengers in netrin-1 signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Netrin receptor DCC Netrin-1 Phosphatidylinositol transfer protein alpha isoform Short transient receptor potential channel 1 Short transient receptor potential channel 3 Short transient receptor potential channel 4 Short transient receptor potential channel 5 Short transient receptor potential channel 6 Short transient receptor potential channel 7	O95631 P19174 P43146 P48995 Q00169 Q13507 Q9HCX4 Q9UBN4 Q9UL62 Q9Y210	DCC IGDCC1 NTN1 NTN1L PITPN PITPNA PLC1 PLCG1 TRP1 TRP3 TRP5 TRP6 TRP7 TRPC1 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7
Synthesis of UDP-N-acetyl-glucosamine	Glucosamine 6-phosphate N-acetyltransferase Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 N-acetyl-D-glucosamine kinase N-acetylglucosamine-6-phosphate deacetylase N-acylglucosamine 2-epimerase Phosphoacetylglucosamine mutase UDP-N-acetylhexosamine pyrophosphorylase	O94808 O95394 P51606 Q06210 Q16222 Q96EK6 Q9UJ70 Q9Y303	AGM1 AMDHD2 GFAT GFPT GFPT1 GFPT2 GNA1 GNPNAT1 NAGK PGM3 RENBP SPAG2 UAP1
LXRs regulate gene expression linked to lipogenesis	Angiopoietin-related protein 3 Fatty acid synthase Nuclear receptor-interacting protein 1 Oxysterols receptor LXR-alpha Oxysterols receptor LXR-beta Retinoic acid receptor RXR-alpha Retinoic acid receptor RXR-beta Stearoyl-CoA desaturase	O00767 P19793 P28702 P48552 P49327 P55055 Q13133 Q9Y5C1	ANGPT5 ANGPTL3 FADS5 FAS FASN LXRA LXRB NER NR1H2 NR1H3 NR2B1 NR2B2 NRIP1 RXRA RXRB SCD SCD1 SCDOS UNR
G beta:gamma signalling through CDC42	Cell division control protein 42 homolog Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Rho guanine nucleotide exchange factor 6 Serine/threonine-protein kinase PAK 1	O14610 O14775 O60262 P16520 P50150 P50151 P59768 P60953 P61952 P62873 P62879 P63211 P63215 P63218 Q13153 Q15052 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	ARHGEF6 CDC42 COOL2 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 KIAA0006 PAK1 PIXA
Defective SLC22A5 causes systemic primary carnitine deficiency (CDSP)	Organic cation/carnitine transporter 2	O76082	OCTN2 SLC22A5
TRIF-mediated programmed cell death	Caspase-8 FAS-associated death domain protein Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Receptor-interacting serine/threonine-protein kinase 1 Receptor-interacting serine/threonine-protein kinase 3 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 Toll-like receptor 4	O00206 P08571 Q13158 Q13546 Q14790 Q86XR7 Q8IUC6 Q9Y572 Q9Y6Y9	CASP8 CD14 ESOP1 FADD LY96 MCH5 MD2 MORT1 PRVTIRB RIP RIP1 RIP3 RIPK1 RIPK3 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAM TRIF
Processive synthesis on the C-strand of the telomere	Adrenocortical dysplasia protein homolog Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN DNA ligase 1 DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 Proliferating cell nuclear antigen Protection of telomeres protein 1 RecQ-like DNA helicase BLM TERF1-interacting nuclear factor 2 Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2	P12004 P18858 P28340 P49005 P54132 P54274 Q14191 Q15054 Q15554 Q96AP0 Q9BSI4 Q9HCU8 Q9NUX5 Q9NYB0	ACD BLM DRIP5 KIAA0039 LIG1 PCNA PIN2 PIP1 POLD POLD1 POLD2 POLD3 POLD4 POLDS POT1 PTOP RAP1 RECQ2 RECQ3 RECQL2 RECQL3 TERF1 TERF2 TERF2IP TIN2 TINF2 TINT1 TPP1 TRBF1 TRBF2 TRF TRF1 TRF2 WRN
Defective ABCB11 causes PFIC2 and BRIC2	Bile salt export pump	O95342	ABCB11 BSEP

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