GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **901 - 925** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲
Downstream signal transduction	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Adapter molecule crk Breast cancer anti-estrogen resistance protein 1 Crk-like protein Cytoplasmic protein NCK2 GTPase HRas GTPase NRas Growth factor receptor-bound protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit B Proto-oncogene tyrosine-protein kinase Src Rap guanine nucleotide exchange factor 1 Ras GTPase-activating protein 1 SH2/SH3 adapter protein NCK1 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Signal transducer and activator of transcription 6 Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O00459 O43639 P01111 P01112 P01127 P09619 P12931 P16234 P16333 P19174 P20936 P27986 P40763 P42224 P42226 P42229 P42336 P42338 P46108 P46109 P51692 P56945 Q06124 Q07889 Q13905 Q14451	APRF BCAR1 CAS CASS1 CRK CRKAS CRKL GAP GRB1 GRB4 GRB7 GRF2 HRAS HRAS1 NCK NCK1 NCK2 NRAS PDGF2 PDGFB PDGFR PDGFR1 PDGFR2 PDGFRA PDGFRB PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 PLC1 PLCG1 PTP2C PTPN11 RAPGEF1 RASA RASA1 RHEPDGFRA SHPTP2 SIS SOS1 SRC SRC1 STAT1 STAT3 STAT5 STAT5A STAT5B STAT6
Signaling by cytosolic FGFR1 fusion mutants	Breakpoint cluster region protein Centrosomal protein 43 Cleavage and polyadenylation specificity factor subunit 6 FGFR1 oncogene partner 2 GRB2-associated-binding protein 2 Homeobox protein cut-like 1 Leucine-rich repeat flightless-interacting protein 1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Transcription intermediary factor 1-alpha Unconventional myosin-XVIIIa Zinc finger MYM-type protein 2	O15164 O95684 P11274 P27986 P39880 P40763 P42224 P42229 P42336 P51692 Q16630 Q32MZ4 Q92614 Q9NVK5 Q9UBW7 Q9UQC2	APRF BCR BCR1 CD245 CEP43 CFIM68 CPSF6 CUTL1 CUX1 D22S11 FGFR1OP FGFR1OP2 FIM FOP GAB2 GCF2 GRB1 KIAA0216 KIAA0571 LRRFIP1 MYO18A MYSPDZ PIK3CA PIK3R1 RAMP RNF82 STAT1 STAT3 STAT5 STAT5A STAT5B TIAF1 TIF1 TIF1A TRIM24 TRIP ZMYM2 ZNF198
Interleukin-37 signaling	Caspase-1 Interleukin-18 receptor 1 Interleukin-18-binding protein Interleukin-37 Mothers against decapentaplegic homolog 3 Serine/threonine-protein kinase TBK1 Signal transducer and activator of transcription 3 Single Ig IL-1-related receptor Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 12 Tyrosine-protein phosphatase non-receptor type 13 Tyrosine-protein phosphatase non-receptor type 14 Tyrosine-protein phosphatase non-receptor type 18 Tyrosine-protein phosphatase non-receptor type 20 Tyrosine-protein phosphatase non-receptor type 23 Tyrosine-protein phosphatase non-receptor type 2 Tyrosine-protein phosphatase non-receptor type 4 Tyrosine-protein phosphatase non-receptor type 5 Tyrosine-protein phosphatase non-receptor type 6 Tyrosine-protein phosphatase non-receptor type 7 Tyrosine-protein phosphatase non-receptor type 9	O95998 P17706 P29074 P29350 P29466 P35236 P40763 P43378 P54829 P84022 Q05209 Q06124 Q12923 Q13478 Q15678 Q4JDL3 Q6IA17 Q99952 Q9H3S7 Q9NZH6 Q9UHD2	APRF BDP1 CASP1 FIL1Z HCP IL18BP IL18R1 IL1BC IL1BCE IL1F7 IL1H4 IL1RP1 IL1RRP IL37 KIAA1471 MADH3 NAK PEZ PNP1 PTP1C PTP1E PTP2C PTPD2 PTPL1 PTPN11 PTPN12 PTPN13 PTPN14 PTPN18 PTPN2 PTPN20 PTPN20A PTPN20B PTPN23 PTPN4 PTPN5 PTPN6 PTPN7 PTPN9 PTPT SHPTP2 SIGIRR SMAD3 STAT3 TBK1
PTK6 Activates STAT3	Protein-tyrosine kinase 6 Signal transducer and activator of transcription 3 Signal-transducing adaptor protein 2 Suppressor of cytokine signaling 3	O14543 P40763 Q13882 Q9UGK3	APRF BKS BRK CIS3 PTK6 SOCS3 SSI3 STAP2 STAT3
Signaling by CSF1 (M-CSF) in myeloid cells	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 E3 ubiquitin-protein ligase CBL GRB2-associated-binding protein 2 GRB2-associated-binding protein 3 GRB2-related adapter protein 2 GTPase KRas Interleukin-34 Macrophage colony-stimulating factor 1 receptor Macrophage colony-stimulating factor 1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Polyubiquitin-B Polyubiquitin-C Proto-oncogene tyrosine-protein kinase Src SHC-transforming protein 1 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Son of sevenless homolog 1 THO complex subunit 5 homolog Tyrosine-protein kinase Fyn Tyrosine-protein kinase HCK Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00329 O15357 O75791 P01116 P06241 P07333 P07947 P07948 P08631 P09603 P0CG47 P0CG48 P12931 P16885 P22681 P27986 P29353 P40763 P42224 P42336 P42338 P62979 P62987 Q06124 Q07889 Q13769 Q6ZMJ4 Q8WWW8 Q92835 Q9UQC2	APRF C16orf77 C22orf19 CBL CBL2 CSF1 CSF1R FMS FYN GAB2 GAB3 GADS GRAP2 GRB1 GRB2L GRID HCK IL34 INPP5D INPPL1 JTK8 KIAA0571 KIAA0983 KRAS KRAS2 LYN PIK3C1 PIK3CA PIK3CB PIK3CD PIK3R1 PLCG2 PTP2C PTPN11 RASK2 RNF55 RPS27A SHC SHC1 SHCA SHIP SHIP1 SHIP2 SHPTP2 SOS1 SRC SRC1 STAT1 STAT3 THOC5 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 YES YES1
Interleukin-10 signaling	C-C chemokine receptor type 1 C-C chemokine receptor type 2 C-C chemokine receptor type 5 C-C motif chemokine 19 C-C motif chemokine 20 C-C motif chemokine 22 C-C motif chemokine 2 C-C motif chemokine 3-like 1 C-C motif chemokine 3 C-C motif chemokine 4 C-C motif chemokine 5 C-X-C motif chemokine 10 C-X-C motif chemokine 2 Granulocyte colony-stimulating factor Granulocyte-macrophage colony-stimulating factor Growth-regulated alpha protein Intercellular adhesion molecule 1 Interleukin-1 alpha Interleukin-1 beta Interleukin-1 receptor antagonist protein Interleukin-1 receptor type 1 Interleukin-1 receptor type 2 Interleukin-10 receptor subunit alpha Interleukin-10 receptor subunit beta Interleukin-10 Interleukin-12 subunit alpha Interleukin-12 subunit beta Interleukin-18 Interleukin-6 Interleukin-8 Leukemia inhibitory factor Low affinity immunoglobulin epsilon Fc receptor Macrophage colony-stimulating factor 1 Metalloproteinase inhibitor 1 Non-receptor tyrosine-protein kinase TYK2 Platelet-activating factor receptor Prostaglandin G/H synthase 2 Signal transducer and activator of transcription 3 T-lymphocyte activation antigen CD80 T-lymphocyte activation antigen CD86 Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor superfamily member 1B Tumor necrosis factor Tyrosine-protein kinase JAK1 fMet-Leu-Phe receptor	O00626 P01033 P01375 P01583 P01584 P02778 P04141 P05231 P05362 P06734 P09341 P09603 P09919 P10145 P10147 P13236 P13500 P13501 P14778 P15018 P16619 P18510 P19438 P19875 P20333 P21462 P22301 P23458 P25105 P27930 P29459 P29460 P29597 P32246 P33681 P35354 P40763 P41597 P42081 P51681 P78556 Q08334 Q13651 Q14116 Q99731	APRF C17orf33 CCL19 CCL2 CCL20 CCL22 CCL3 CCL3L1 CCL3L3 CCL4 CCL5 CCR1 CCR2 CCR5 CD23A CD28LG CD28LG1 CD28LG2 CD80 CD86 CLEC4J CLGI CMKBR1 CMKBR2 CMKBR5 CMKR1 COX2 CRFB4 CSF1 CSF2 CSF3 CXCL1 CXCL10 CXCL2 CXCL8 D17S136E D17S1718 D21S58 D21S66 ELC FCE2 FCER2 FPR1 G0S19-1 G0S19-2 GCSF GMCSF GRO GRO1 GRO2 GROA GROB HILDA ICAM1 IFNB2 IGEBF IGIF IL10 IL10R IL10RA IL10RB IL12A IL12B IL18 IL1A IL1B IL1F1 IL1F2 IL1F3 IL1F4 IL1R IL1R1 IL1R2 IL1RA IL1RB IL1RN IL1RT1 IL6 IL8 INP10 JAK1 JAK1A JAK1B LAB7 LAG1 LARC LIF MCP1 MDC MGSA MIP1A MIP1B MIP2A MIP3A MIP3B NKSF1 NKSF2 PAFR PTAFR PTGS2 SCYA19 SCYA2 SCYA20 SCYA22 SCYA3 SCYA3L1 SCYA4 SCYA5 SCYAR1 SCYB1 SCYB10 SCYB2 STAT3 TIMP TIMP1 TNF TNFA TNFAR TNFBR TNFR1 TNFR2 TNFRSF1A TNFRSF1B TNFSF2 TYK2
Inactivation of CSF3 (G-CSF) signaling	Cullin-5 Elongin-B Elongin-C Granulocyte colony-stimulating factor receptor Granulocyte colony-stimulating factor Non-receptor tyrosine-protein kinase TYK2 Polyubiquitin-B Polyubiquitin-C RING-box protein 2 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase HCK Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14543 O15524 O60674 P07948 P08631 P09919 P0CG47 P0CG48 P23458 P29597 P40763 P42224 P42229 P43405 P51668 P51692 P61077 P62837 P62979 P62987 Q15369 Q15370 Q93034 Q99062 Q9UBF6	APRF C17orf33 CIS3 CSF3 CSF3R CUL5 ELOB ELOC GCSF GCSFR HCK JAK1 JAK1A JAK1B JAK2 JTK8 LYN PUBC1 RBX2 RNF7 ROC2 RPS27A SAG SFT SOCS1 SOCS3 SSI1 SSI3 STAT1 STAT3 STAT5 STAT5A STAT5B SYK TCEB1 TCEB2 TIP3 TYK2 UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBC5C UBCEP1 UBCEP2 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBE2D1 UBE2D2 UBE2D3 VACM1
Interleukin-27 signaling	Calnexin Cytokine receptor-like factor 1 Interleukin-27 receptor subunit alpha Interleukin-27 subunit alpha Interleukin-27 subunit beta Interleukin-6 receptor subunit beta Non-receptor tyrosine-protein kinase TYK2 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2	O60674 O75462 P23458 P27824 P29597 P40189 P40763 P42224 Q14213 Q6UWB1 Q8NEV9	APRF CANX CRL1 CRLF1 EBI3 IL27 IL27A IL27B IL27RA IL30 IL6ST JAK1 JAK1A JAK1B JAK2 STAT1 STAT3 TCCR TYK2 WSX1
Interleukin-35 Signalling	Calnexin Interleukin-12 receptor subunit beta-2 Interleukin-12 subunit alpha Interleukin-27 receptor subunit alpha Interleukin-27 subunit beta Interleukin-6 receptor subunit beta Non-receptor tyrosine-protein kinase TYK2 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2	O60674 P23458 P27824 P29459 P29597 P40189 P40763 P42224 Q14213 Q14765 Q6UWB1 Q99665	APRF CANX CRL1 EBI3 IL12A IL12RB2 IL27B IL27RA IL6ST JAK1 JAK1A JAK1B JAK2 NKSF1 STAT1 STAT3 STAT4 TCCR TYK2 WSX1
Interleukin-6 signaling	E3 ubiquitin-protein ligase CBL Interleukin-6 receptor subunit alpha Interleukin-6 receptor subunit beta Interleukin-6 Non-receptor tyrosine-protein kinase TYK2 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein phosphatase non-receptor type 11	O14543 O60674 P05231 P08887 P22681 P23458 P29597 P40189 P40763 P42224 Q06124	APRF CBL CBL2 CIS3 IFNB2 IL6 IL6R IL6ST JAK1 JAK1A JAK1B JAK2 PTP2C PTPN11 RNF55 SHPTP2 SOCS3 SSI3 STAT1 STAT3 TYK2
Signaling by SCF-KIT	Chymase GRB2-associated-binding protein 2 GRB2-related adapter protein 2 GRB2-related adapter protein GTPase HRas GTPase NRas Growth factor receptor-bound protein 10 Growth factor receptor-bound protein 7 Mast/stem cell growth factor receptor Kit Matrix metalloproteinase-9 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Protein kinase C alpha type Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Receptor-type tyrosine-protein phosphatase U Serine/threonine-protein kinase Chk1 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Son of sevenless homolog 1 Tyrosine-protein kinase Fer Tyrosine-protein kinase Fes/Fps Tyrosine-protein kinase Fyn Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lck Tyrosine-protein kinase Lyn Tyrosine-protein kinase Tec Tyrosine-protein kinase Yes Tyrosine-protein phosphatase non-receptor type 11	O00459 O14757 O60674 O75791 P01111 P01112 P06239 P06241 P07332 P07947 P07948 P10721 P14780 P15498 P16591 P17252 P23946 P27986 P40763 P42224 P42229 P42336 P42680 P51692 P63000 Q06124 Q07889 Q13322 Q13588 Q14451 Q92569 Q92729 Q9UQC2	APRF CHEK1 CHK1 CLG4B CMA1 CYH CYM FER FES FMI FPS FYN GAB2 GADS GRAP GRAP2 GRB1 GRB10 GRB2L GRB7 GRBIR GRID HRAS HRAS1 JAK2 JTK8 KIAA0207 KIAA0571 KIT LCK LYN MMP9 NRAS PCP2 PIK3CA PIK3R1 PIK3R2 PIK3R3 PKCA PRKACA PRKCA PSCTK4 PTP2C PTPN11 PTPRO PTPRU RAC1 SCFR SHPTP2 SOS1 STAT1 STAT3 STAT5 STAT5A STAT5B TC25 TEC TYK3 VAV VAV1 YES YES1
Signaling by Leptin	Insulin receptor substrate 1 Insulin receptor substrate 2 Leptin Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK2 Tyrosine-protein phosphatase non-receptor type 11	O14543 O60674 P35568 P40763 P41159 P42229 P51692 Q06124 Q9Y4H2	APRF CIS3 IRS1 IRS2 JAK2 LEP OB OBS PTP2C PTPN11 SHPTP2 SOCS3 SSI3 STAT3 STAT5 STAT5A STAT5B
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation	Developmental pluripotency-associated protein 4 Ephrin type-A receptor 1 Fibroblast growth factor 2 Forkhead box protein D3 Homeobox protein NANOG POU domain, class 5, transcription factor 1 Protein Cripto Sal-like protein 1 Sal-like protein 4 Signal transducer and activator of transcription 3 Transcription factor SOX-2 Zinc finger protein ZIC 3	O60481 P09038 P13385 P21709 P40763 P48431 Q01860 Q7L190 Q9H9S0 Q9NSC2 Q9UJQ4 Q9UJU5	APRF CRIPTO CRIPTO-1 DPPA4 EPH EPHA1 EPHT EPHT1 FGF2 FGFB FOXD3 HFH2 NANOG OCT3 OCT4 OTF3 POU5F1 SAL1 SALL1 SALL4 SOX2 STAT3 TDGF1 ZIC3 ZNF203 ZNF794 ZNF797
Interleukin-23 signaling	Interleukin-12 receptor subunit beta-1 Interleukin-12 subunit beta Interleukin-23 receptor Interleukin-23 subunit alpha Non-receptor tyrosine-protein kinase TYK2 Protein disulfide-isomerase Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Tyrosine-protein kinase JAK2	O60674 P07237 P29460 P29597 P40763 P42701 Q14765 Q5VWK5 Q9NPF7	APRF ERBA2L IL12B IL12R IL12RB IL12RB1 IL23A IL23R JAK2 NKSF2 P4HB PDI PDIA1 PO4DB SGRF STAT3 STAT4 TYK2
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants	GTPase HRas GTPase NRas Mast/stem cell growth factor receptor Kit Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Son of sevenless homolog 1 Tyrosine-protein kinase Fyn Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lck Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes	O00459 O60674 P01111 P01112 P06239 P06241 P07947 P07948 P10721 P27986 P40763 P42224 P42229 P42336 P51692 Q07889 Q92569	APRF FYN GRB1 HRAS HRAS1 JAK2 JTK8 KIT LCK LYN NRAS PIK3CA PIK3R1 PIK3R2 PIK3R3 SCFR SOS1 STAT1 STAT3 STAT5 STAT5A STAT5B YES YES1
Signaling by PDGFRA extracellular domain mutants	GTPase HRas GTPase NRas Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Platelet-derived growth factor receptor alpha Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Son of sevenless homolog 1	O00459 P01111 P01112 P16234 P27986 P40763 P42224 P42336 P42338 Q07889	APRF GRB1 HRAS HRAS1 NRAS PDGFR2 PDGFRA PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 RHEPDGFRA SOS1 STAT1 STAT3
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants	GTPase HRas GTPase NRas Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Platelet-derived growth factor receptor alpha Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Son of sevenless homolog 1	O00459 P01111 P01112 P16234 P27986 P40763 P42224 P42336 P42338 Q07889	APRF GRB1 HRAS HRAS1 NRAS PDGFR2 PDGFRA PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 RHEPDGFRA SOS1 STAT1 STAT3
MET activates STAT3	Hepatocyte growth factor receptor Hepatocyte growth factor Signal transducer and activator of transcription 3	P08581 P14210 P40763	APRF HGF HPTA MET STAT3
Interleukin-21 signaling	Cytokine receptor common subunit gamma Interleukin-21 receptor Interleukin-21 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK3	P23458 P31785 P40763 P42224 P42229 P51692 P52333 Q14765 Q9HBE4 Q9HBE5	APRF IL21 IL21R IL2RG JAK1 JAK1A JAK1B JAK3 NILR STAT1 STAT3 STAT4 STAT5 STAT5A STAT5B
Interleukin-9 signaling	Cytokine receptor common subunit gamma Interleukin-9 receptor Interleukin-9 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK3	P15248 P23458 P31785 P40763 P42224 P42229 P51692 P52333 Q01113	APRF IL2RG IL9 IL9R JAK1 JAK1A JAK1B JAK3 STAT1 STAT3 STAT5 STAT5A STAT5B
Signalling to STAT3	Beta-nerve growth factor High affinity nerve growth factor receptor Signal transducer and activator of transcription 3	P01138 P04629 P40763	APRF MTC NGF NGFB NTRK1 STAT3 TRK TRKA
Establishment of Sister Chromatid Cohesion	Cohesin subunit SA-1 Cohesin subunit SA-2 Double-strand-break repair protein rad21 homolog N-acetyltransferase ESCO1 N-acetyltransferase ESCO2 Sister chromatid cohesion protein PDS5 homolog A Sister chromatid cohesion protein PDS5 homolog B Sororin Structural maintenance of chromosomes protein 1A Structural maintenance of chromosomes protein 3 Wings apart-like protein homolog	O60216 Q14683 Q29RF7 Q56NI9 Q5FWF5 Q7Z5K2 Q8N3U4 Q8WVM7 Q96FF9 Q9NTI5 Q9UQE7	APRIN AS3 BAM BMH CDCA5 CSPG6 DXS423E EFO1 ESCO1 ESCO2 FOE HR21 KIAA0078 KIAA0178 KIAA0261 KIAA0648 KIAA0979 KIAA1911 NXP1 PDS5 PDS5A PDS5B RAD21 SA1 SA2 SB1.8 SCC1 SCC3 SMC1 SMC1A SMC1L1 SMC3 SMC3L1 STAG1 STAG2 WAPAL WAPL
Cohesin Loading onto Chromatin	Cohesin subunit SA-1 Cohesin subunit SA-2 Double-strand-break repair protein rad21 homolog MAU2 chromatid cohesion factor homolog Nipped-B-like protein Sister chromatid cohesion protein PDS5 homolog A Sister chromatid cohesion protein PDS5 homolog B Structural maintenance of chromosomes protein 1A Structural maintenance of chromosomes protein 3 Wings apart-like protein homolog	O60216 Q14683 Q29RF7 Q6KC79 Q7Z5K2 Q8N3U4 Q8WVM7 Q9NTI5 Q9UQE7 Q9Y6X3	APRIN AS3 BAM BMH CSPG6 DXS423E FOE HR21 IDN3 KIAA0078 KIAA0178 KIAA0261 KIAA0648 KIAA0892 KIAA0979 MAU2 NIPBL NXP1 PDS5 PDS5A PDS5B RAD21 SA1 SA2 SB1.8 SCC1 SCC2 SCC3 SCC4 SMC1 SMC1A SMC1L1 SMC3 SMC3L1 STAG1 STAG2 WAPAL WAPL
Defective APRT disrupts adenine salvage	Adenine phosphoribosyltransferase	P07741	APRT
Regulation of KIT signaling	E3 ubiquitin-protein ligase CBL Mast/stem cell growth factor receptor Kit Protein kinase C alpha type SH2B adapter protein 2 SH2B adapter protein 3 Son of sevenless homolog 1 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 6 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lck Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes Tyrosine-protein phosphatase non-receptor type 6	O14492 O14544 O15524 P06239 P06241 P07947 P07948 P10721 P17252 P22681 P29350 Q07889 Q9UQQ2	APS CBL CBL2 CIS4 FYN HCP JTK8 KIT LCK LNK LYN PKCA PRKACA PRKCA PTP1C PTPN6 RNF55 SCFR SH2B2 SH2B3 SOCS1 SOCS4 SOCS6 SOS1 SSI1 TIP3 YES YES1

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