GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **1226 - 1250** of **2090** in total

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Pathway Name ▼	Protein Name	UniProt ID	Gene Symbol
Inactivation, recovery and regulation of the phototransduction cascade	Calmodulin-1 Calmodulin-lysine N-methyltransferase Cyclic nucleotide-gated channel alpha-1 Cyclic nucleotide-gated channel beta-1 Glycylpeptide N-tetradecanoyltransferase 1 Glycylpeptide N-tetradecanoyltransferase 2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(t) subunit alpha-1 Guanylyl cyclase-activating protein 1 Guanylyl cyclase-activating protein 2 Guanylyl cyclase-activating protein 3 Methionine aminopeptidase 1 Methionine aminopeptidase 2 Protein farnesyltransferase subunit beta Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha Protein kinase C alpha type Protein kinase C theta type Recoverin Regulator of G-protein signaling 9-binding protein Retinal guanylyl cyclase 1 Retinal guanylyl cyclase 2 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Rhodopsin kinase GRK1 Rhodopsin kinase GRK7 Rhodopsin Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta S-arrestin Serine/threonine-protein phosphatase with EF-hands 1	O14829 O60551 O95843 P08100 P0DP23 P10523 P11488 P16499 P17252 P18545 P29973 P30419 P35243 P35913 P43080 P49354 P49356 P50579 P51841 P53582 P62873 P63211 Q02846 Q04759 Q14028 Q15835 Q6ZS82 Q7Z624 Q8WTQ7 Q9UMX6	C2orf34 C6orf131 CALM CALM1 CAM CAM1 CAMKMT CLNMT CNCG CNCG1 CNCG2 CNCG3L CNCG4 CNGA1 CNGB1 CORD6 FNTA FNTB GCAP GCAP1 GCAP2 GCAP3 GNAT1 GNATR GNB1 GNGT1 GPRK7 GRK1 GRK7 GUC1A4 GUC2D GUC2F GUCA1 GUCA1A GUCA1B GUCA1C GUCY2D GUCY2F KIAA0094 METAP1 METAP2 MNPEP NMT NMT1 NMT2 OPN2 P67EIF2 PDE6A PDE6B PDE6G PDEA PDEB PDEG PKCA PPEF PPEF1 PPP7C PRKACA PRKCA PRKCQ PRKCT R9AP RCNC2 RCV1 RCVRN RETGC RETGC1 RETGC2 RGS9BP RHO RHOK SAG
Inactivation of CSF3 (G-CSF) signaling	Cullin-5 Elongin-B Elongin-C Granulocyte colony-stimulating factor receptor Granulocyte colony-stimulating factor Non-receptor tyrosine-protein kinase TYK2 Polyubiquitin-B Polyubiquitin-C RING-box protein 2 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase HCK Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14543 O15524 O60674 P07948 P08631 P09919 P0CG47 P0CG48 P23458 P29597 P40763 P42224 P42229 P43405 P51668 P51692 P61077 P62837 P62979 P62987 Q15369 Q15370 Q93034 Q99062 Q9UBF6	APRF C17orf33 CIS3 CSF3 CSF3R CUL5 ELOB ELOC GCSF GCSFR HCK JAK1 JAK1A JAK1B JAK2 JTK8 LYN PUBC1 RBX2 RNF7 ROC2 RPS27A SAG SFT SOCS1 SOCS3 SSI1 SSI3 STAT1 STAT3 STAT5 STAT5A STAT5B SYK TCEB1 TCEB2 TIP3 TYK2 UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBC5C UBCEP1 UBCEP2 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBE2D1 UBE2D2 UBE2D3 VACM1
Inactivation of CDC42 and RAC1	Cell division control protein 42 homolog Ras-related C3 botulinum toxin substrate 1 Rho GTPase-activating protein 39 Roundabout homolog 1 SLIT-ROBO Rho GTPase-activating protein 1 SLIT-ROBO Rho GTPase-activating protein 2 SLIT-ROBO Rho GTPase-activating protein 3 Slit homolog 2 protein	O43295 O75044 O94813 P60953 P63000 Q7Z6B7 Q9C0H5 Q9Y6N7	ARHGAP13 ARHGAP14 ARHGAP34 ARHGAP39 CDC42 DUTT1 FNBP2 KIAA0411 KIAA0456 KIAA1156 KIAA1304 KIAA1688 MEGAP RAC1 ROBO1 SLIL3 SLIT2 SRGAP1 SRGAP2 SRGAP2A SRGAP3 TC25
Inactivation of APC/C via direct inhibition of the APC/C complex	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Mitotic checkpoint protein BUB3 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Mitotic spindle assembly checkpoint protein MAD2A Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S	O00762 O43684 O60566 P30260 P51668 P51965 P60006 Q12834 Q13042 Q13257 Q16763 Q8NHZ8 Q96DE5 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM13	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 BUB1B BUB3 BUBR1 C10orf104 C11orf51 C9orf17 CDC16 CDC20 CDC23 CDC26 CDC27 CENP-27 D0S1430E D17S978E E2EPF KIAA1406 MAD2 MAD2L1 MAD3L SFT SSK1 TSG24 UBC5A UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S
Impaired BRCA2 translocation to the nucleus	26S proteasome complex subunit SEM1 Breast cancer type 2 susceptibility protein	P51587 P60896	BRCA2 C7orf76 DSS1 FACD FANCD1 SEM1 SHFDG1 SHFM1
Impaired BRCA2 binding to SEM1 (DSS1)	26S proteasome complex subunit SEM1 Breast cancer type 2 susceptibility protein	P51587 P60896	BRCA2 C7orf76 DSS1 FACD FANCD1 SEM1 SHFDG1 SHFM1
Impaired BRCA2 binding to RAD51	26S proteasome complex subunit SEM1 ATR-interacting protein BRCA1-associated RING domain protein 1 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Breast cancer type 2 susceptibility protein Cell cycle checkpoint control protein RAD9A Cell cycle checkpoint control protein RAD9B Cell cycle checkpoint protein RAD17 Cell cycle checkpoint protein RAD1 Checkpoint protein HUS1 DNA endonuclease RBBP8 DNA repair protein RAD50 DNA repair protein RAD51 homolog 1 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 2-binding protein 1 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 Exonuclease 1 Fanconi anemia group J protein Histone acetyltransferase KAT5 Nibrin RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Serine-protein kinase ATM Serine/threonine-protein kinase ATR	O60671 O60921 O60934 O75943 P15927 P27694 P35244 P35249 P35250 P38398 P40937 P40938 P49959 P51530 P51587 P54132 P60896 Q06609 Q13315 Q13472 Q13535 Q14191 Q6WBX8 Q8WXE1 Q92547 Q92878 Q92993 Q96E14 Q99638 Q99708 Q99728 Q9BSD3 Q9BX63 Q9H9A7 Q9UQ84	AGS1 ATM ATR ATRIP BACH1 BARD1 BLM BRCA1 BRCA2 BRIP1 C12orf32 C16orf75 C7orf76 C9orf76 CTIP DNA2 DNA2L DSS1 EXO1 EXOI FACD FANCD1 FANCJ FRP1 HEX1 HNGS1 HTATIP HUS1 KAT5 KIAA0083 KIAA0259 MRE11 MRE11A NBN NBS NBS1 P95 R24L RAD1 RAD17 RAD50 RAD51 RAD51A RAD9A RAD9B RBBP8 REC1 RECA RECQ2 RECQ3 RECQL2 RECQL3 REPA1 REPA2 REPA3 RFC2 RFC3 RFC4 RFC5 RHINO RHNO1 RMI1 RMI2 RNF53 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 SEM1 SHFDG1 SHFM1 TIP60 TOP3 TOP3A TOPBP1 WRN
Impaired BRCA2 binding to PALB2	BRCA1-associated RING domain protein 1 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Breast cancer type 2 susceptibility protein DNA endonuclease RBBP8 DNA repair protein RAD50 DNA repair protein RAD51 homolog 1 DNA repair protein RAD51 homolog 2 DNA repair protein RAD51 homolog 3 DNA repair protein RAD51 homolog 4 DNA repair protein XRCC2 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 Exonuclease 1 Fanconi anemia group J protein Histone acetyltransferase KAT5 Nibrin Partner and localizer of BRCA2 RAD51-associated protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Serine-protein kinase ATM	O15315 O43502 O43543 O60934 O75771 P38398 P49959 P51530 P51587 P54132 Q06609 Q13315 Q13472 Q14191 Q86YC2 Q92878 Q92993 Q96B01 Q96E14 Q99708 Q99728 Q9BX63 Q9H9A7 Q9UQ84	ATM BACH1 BARD1 BLM BRCA1 BRCA2 BRIP1 C16orf75 C9orf76 CTIP DNA2 DNA2L EXO1 EXOI FACD FANCD1 FANCJ FANCN HEX1 HNGS1 HTATIP KAT5 KIAA0083 MRE11 MRE11A NBN NBS NBS1 P95 PALB2 PIR51 RAD50 RAD51 RAD51A RAD51AP1 RAD51B RAD51C RAD51D RAD51L1 RAD51L2 RAD51L3 RBBP8 REC2 RECA RECQ2 RECQ3 RECQL2 RECQL3 RMI1 RMI2 RNF53 TIP60 TOP3 TOP3A WRN XRCC2
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	65 kDa phosphoprotein Antigen-presenting glycoprotein CD1d B-cell receptor CD22 B-lymphocyte antigen CD19 Beta-2-microglobulin C-type lectin domain family 2 member B C-type lectin domain family 2 member D C-type lectin domain family 4 member G CD160 antigen CD21 protein (Fragment) CD226 antigen CD40 ligand CD81 antigen CD99 antigen CMRF35-like molecule 1 CMRF35-like molecule 2 CMRF35-like molecule 5 CMRF35-like molecule 6 CMRF35-like molecule 7 CMRF35-like molecule 8 CMRF35-like molecule 9 Cadherin-1 Cell surface glycoprotein CD200 receptor 1 Collectin-12 Complement C3 Coxsackievirus and adenovirus receptor Cytotoxic and regulatory T-cell molecule HLA class I histocompatibility antigen, A alpha chain HLA class I histocompatibility antigen, B alpha chain HLA class I histocompatibility antigen, C alpha chain HLA class I histocompatibility antigen, alpha chain E HLA class I histocompatibility antigen, alpha chain F HLA class I histocompatibility antigen, alpha chain G Hemagglutinin-neuraminidase Hemagglutinin Hematopoietic cell signal transducer High affinity immunoglobulin gamma Fc receptor I IGHV7-81 protein Immunoglobulin heavy variable 1-2 Immunoglobulin heavy variable 1-46 Immunoglobulin heavy variable 1-69 Immunoglobulin heavy variable 2-5 Immunoglobulin heavy variable 2-70 Immunoglobulin heavy variable 3-11 Immunoglobulin heavy variable 3-13 Immunoglobulin heavy variable 3-23 Immunoglobulin heavy variable 3-30 Immunoglobulin heavy variable 3-33 Immunoglobulin heavy variable 3-48 Immunoglobulin heavy variable 3-53 Immunoglobulin heavy variable 3-7 Immunoglobulin heavy variable 3-9 Immunoglobulin heavy variable 4-34 Immunoglobulin heavy variable 4-39 Immunoglobulin heavy variable 4-59 Immunoglobulin kappa constant Immunoglobulin kappa variable 1-12 Immunoglobulin kappa variable 1-16 Immunoglobulin kappa variable 1-17 Immunoglobulin kappa variable 1-33 Immunoglobulin kappa variable 1-39 Immunoglobulin kappa variable 1-5 Immunoglobulin kappa variable 1D-12 Immunoglobulin kappa variable 1D-16 Immunoglobulin kappa variable 1D-33 Immunoglobulin kappa variable 1D-39 Immunoglobulin kappa variable 2-28 Immunoglobulin kappa variable 2-29 Immunoglobulin kappa variable 2-30 Immunoglobulin kappa variable 2D-28 Immunoglobulin kappa variable 2D-30 Immunoglobulin kappa variable 2D-40 Immunoglobulin kappa variable 3-11 Immunoglobulin kappa variable 3-15 Immunoglobulin kappa variable 3-20 Immunoglobulin kappa variable 3D-20 Immunoglobulin kappa variable 4-1 Immunoglobulin kappa variable 5-2 Immunoglobulin lambda constant 1 Immunoglobulin lambda constant 2 Immunoglobulin lambda constant 3 Immunoglobulin lambda constant 6 Immunoglobulin lambda constant 7 Immunoglobulin lambda variable 1-40 Immunoglobulin lambda variable 1-44 Immunoglobulin lambda variable 1-47 Immunoglobulin lambda variable 1-51 Immunoglobulin lambda variable 2-11 Immunoglobulin lambda variable 2-14 Immunoglobulin lambda variable 2-23 Immunoglobulin lambda variable 2-8 Immunoglobulin lambda variable 3-19 Immunoglobulin lambda variable 3-1 Immunoglobulin lambda variable 3-21 Immunoglobulin lambda variable 3-25 Immunoglobulin lambda variable 3-27 Immunoglobulin lambda variable 6-57 Immunoglobulin lambda variable 7-43 Immunolglobulin kappa light chain variable region L22 (Fragment) Integrin alpha-4 Integrin alpha-L Integrin beta-1 Integrin beta-2 Integrin beta-7 Intercellular adhesion molecule 1 Intercellular adhesion molecule 2 Intercellular adhesion molecule 3 Intercellular adhesion molecule 4 Intercellular adhesion molecule 5 Interferon-induced transmembrane protein 1 Junctional adhesion molecule-like Killer cell immunoglobulin-like receptor 2DL1 Killer cell immunoglobulin-like receptor 2DL2 Killer cell immunoglobulin-like receptor 2DL3 Killer cell immunoglobulin-like receptor 2DL4 Killer cell immunoglobulin-like receptor 2DS1 Killer cell immunoglobulin-like receptor 2DS2 Killer cell immunoglobulin-like receptor 3DL1 Killer cell immunoglobulin-like receptor 3DL2 Killer cell lectin-like receptor subfamily B member 1 Killer cell lectin-like receptor subfamily F member 1 Killer cell lectin-like receptor subfamily G member 1 L-selectin Leukocyte immunoglobulin-like receptor subfamily A member 1 Leukocyte immunoglobulin-like receptor subfamily A member 2 Leukocyte immunoglobulin-like receptor subfamily A member 3 Leukocyte immunoglobulin-like receptor subfamily A member 4 Leukocyte immunoglobulin-like receptor subfamily A member 5 Leukocyte immunoglobulin-like receptor subfamily A member 6 Leukocyte immunoglobulin-like receptor subfamily B member 1 Leukocyte immunoglobulin-like receptor subfamily B member 2 Leukocyte immunoglobulin-like receptor subfamily B member 3 Leukocyte immunoglobulin-like receptor subfamily B member 4 Leukocyte immunoglobulin-like receptor subfamily B member 5 Leukocyte-associated immunoglobulin-like receptor 1 Leukocyte-associated immunoglobulin-like receptor 2 Low affinity immunoglobulin gamma Fc region receptor II-b Low affinity immunoglobulin gamma Fc region receptor III-A MHC class I polypeptide-related sequence A MHC class I polypeptide-related sequence B Myeloid cell surface antigen CD33 NKG2-A/NKG2-B type II integral membrane protein NKG2-D type II integral membrane protein Natural cytotoxicity triggering receptor 1 Natural cytotoxicity triggering receptor 2 Natural cytotoxicity triggering receptor 3 ligand 1 Natural cytotoxicity triggering receptor 3 Natural killer cells antigen CD94 Nectin-2 Neural proliferation differentiation and control protein 1 OX-2 membrane glycoprotein Osteoclast-associated immunoglobulin-like receptor PILR alpha-associated neural protein Paired immunoglobulin-like type 2 receptor alpha Paired immunoglobulin-like type 2 receptor beta Poliovirus receptor Putative HLA class I histocompatibility antigen, alpha chain H Putative glycosylation-dependent cell adhesion molecule 1 Retinoic acid early transcript 1E SH2 domain-containing protein 1A SH2 domain-containing protein 1B SLAM family member 6 SLAM family member 7 Sialic acid-binding Ig-like lectin 10 Sialic acid-binding Ig-like lectin 11 Sialic acid-binding Ig-like lectin 12 Sialic acid-binding Ig-like lectin 5 Sialic acid-binding Ig-like lectin 6 Sialic acid-binding Ig-like lectin 7 Sialic acid-binding Ig-like lectin 8 Sialic acid-binding Ig-like lectin 9 Sialoadhesin T cell receptor alpha chain constant T cell receptor alpha variable 19 T cell receptor alpha variable 29/delta variable 5 T cell receptor alpha variable 8-4 T cell receptor beta constant 1 T cell receptor beta variable 12-3 T cell receptor beta variable 7-9 T-cell surface glycoprotein CD1a T-cell surface glycoprotein CD1b T-cell surface glycoprotein CD1c T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD8 alpha chain T-cell surface glycoprotein CD8 beta chain T-cell surface protein tactile TYRO protein tyrosine kinase-binding protein Trem-like transcript 1 protein Trem-like transcript 2 protein Trem-like transcript 4 protein Triggering receptor expressed on myeloid cells 1 Triggering receptor expressed on myeloid cells 2 UGa8H (Fragment) UL16-binding protein 1 UL16-binding protein 3 V1-11 protein (Fragment) V1-13 protein (Fragment) V1-16 protein (Fragment) V1-20 protein (Fragment) V1-3 protein (Fragment) V1-5 protein (Fragment) V1-7 protein (Fragment) V1-9 protein (Fragment) V2-11 protein (Fragment) V2-15 protein (Fragment) V2-17 protein (Fragment) V2-19 protein (Fragment) V2-8 protein (Fragment) V3-2 protein (Fragment) V3-3 protein (Fragment) V3-4 protein (Fragment) V4-1 protein (Fragment) V4-2 protein (Fragment) V4-6 protein (Fragment) V5-1 protein (Fragment) V5-4 protein (Fragment) V5-6 protein (Fragment) Vascular cell adhesion protein 1	A0A075B6P5 A0A075B6S6 A0A0A6YYK7 A0A0C4DH25 A0A0C4DH73 A0M8Q6 A2KUC3 A2NJV5 A2NXD2 A6NI73 A8K4G0 O14796 O14931 O15181 O15389 O43699 O43914 O60880 O75019 O75022 O75023 O76036 O95727 O95944 O95971 P01024 P01593 P01594 P01597 P01599 P01601 P01602 P01611 P01614 P01615 P01619 P01624 P01699 P01700 P01701 P01703 P01704 P01705 P01706 P01709 P01714 P01715 P01717 P01718 P01721 P01732 P01733 P01737 P01742 P01743 P01762 P01763 P01764 P01766 P01767 P01768 P01772 P01780 P01782 P01814 P01817 P01824 P01825 P01834 P01848 P01850 P01889 P01893 P03452 P04211 P04234 P04430 P04432 P04433 P04435 P04437 P04439 P04853 P05107 P05362 P05556 P06126 P06310 P06312 P06315 P06331 P06725 P07766 P08637 P09693 P0CF74 P0CG04 P0DOY2 P0DOY3 P10321 P10966 P12314 P12830 P13164 P13598 P13612 P13747 P14151 P14209 P15151 P15391 P15813 P17693 P19320 P20138 P20273 P20701 P23083 P26010 P26715 P26718 P29016 P29017 P29965 P30511 P31994 P32942 P40200 P41217 P43626 P43627 P43628 P43629 P43630 P43631 P59901 P60033 P61769 P78310 P80748 Q08708 Q12918 Q13241 Q14773 Q14954 Q15762 Q29980 Q29983 Q496F6 Q5KU26 Q5NV61 Q5NV62 Q5NV64 Q5NV65 Q5NV66 Q5NV67 Q5NV68 Q5NV69 Q5NV75 Q5NV79 Q5NV80 Q5NV81 Q5NV82 Q5NV83 Q5NV84 Q5NV85 Q5NV86 Q5NV87 Q5NV89 Q5NV90 Q5NV91 Q5NV92 Q5T2D2 Q68D85 Q6GTX8 Q6ISS4 Q6PI73 Q6PIL0 Q6UXB4 Q6UXG3 Q6UXN2 Q6UXZ3 Q86YT9 Q86YW5 Q8IVK1 Q8IYJ0 Q8IYS5 Q8N149 Q8N423 Q8N6C8 Q8NHJ6 Q8NHL6 Q8TD07 Q8TD46 Q8TDQ1 Q92478 Q92692 Q96DU3 Q96E93 Q96LC7 Q96PQ1 Q96RL6 Q99706 Q9BZM4 Q9BZM6 Q9BZZ2 Q9NP99 Q9NQ25 Q9NQX5 Q9NYZ4 Q9NZC2 Q9NZS2 Q9UBK5 Q9UGN4 Q9UHP7 Q9UKJ0 Q9UKJ1 Q9UMF0 Q9Y286 Q9Y336	1C7 AICL AIRM1 AMICA1 B2M B7H6 BY55 C12orf53 C3 C6orf76 CAR CD11A CD158A CD158B1 CD158B2 CD158D CD158E CD158H CD158J CD158K CD160 CD16A CD18 CD19 CD1A CD1B CD1C CD1D CD200 CD200R CD200R1 CD22 CD225 CD226 CD300A CD300B CD300C CD300D CD300E CD300F CD300LB CD300LD CD300LE CD300LF CD300LG CD305 CD306 CD32 CD33 CD33L CD33L1 CD33L2 CD3D CD3E CD3G CD40L CD40LG CD49D CD81 CD8A CD8B CD8B1 CD94 CD96 CD99 CDH1 CDHE CLAX CLEC15A CLEC2B CLEC2D CLEC4G CLEC5B CLEC5C CLECSF2 CLM1 CLM2 CLM7 CLM9 CLP1 CMRF35 CMRF35A CMRF35A1 CMRF35A2 CMRF35A4 CMRF35A5 CMRF35H COLEC12 CPAMD1 CRTAM CRTR2 CS1 CXADR D12S2489E DAP10 DAP12 DNAM1 DSHP EAT2 FCG1 FCG2 FCG3 FCGR1 FCGR1A FCGR2B FCGR3 FCGR3A FDFACT FNRB GLYCAM1 HA HCST HLA-5.4 HLA-6.0 HLA-6.2 HLA-A HLA-B HLA-C HLA-E HLA-F HLA-G HLA-H HLAA HLAB HLAC HLAE HLAF HLAG HLAH HN HVEB ICAM1 ICAM2 ICAM3 ICAM4 ICAM5 IFI17 IFITM1 IFNRG1 IGFR1 IGFR2 IGFR3 IGHV IGHV1-2 IGHV1-46 IGHV1-69 IGHV2-5 IGHV2-70 IGHV3-11 IGHV3-13 IGHV3-23 IGHV3-30 IGHV3-33 IGHV3-48 IGHV3-53 IGHV3-7 IGHV3-9 IGHV4-34 IGHV4-39 IGHV4-59 IGHV7-81 IGKC IGKV1-12 IGKV1-16 IGKV1-17 IGKV1-33 IGKV1-39 IGKV1-5 IGKV1D-12 IGKV1D-16 IGKV1D-33 IGKV1D-39 IGKV2-28 IGKV2-29 IGKV2-30 IGKV2D-28 IGKV2D-30 IGKV2D-40 IGKV3-11 IGKV3-15 IGKV3-20 IGKV3D-20 IGKV4-1 IGKV5-2 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7 IGLV IGLV1-40 IGLV1-44 IGLV1-47 IGLV1-51 IGLV2-11 IGLV2-14 IGLV2-23 IGLV2-8 IGLV3-1 IGLV3-19 IGLV3-21 IGLV3-25 IGLV3-27 IGLV6-57 IGLV7-43 IGSF12 IGSF13 IGSF16 ILT1 ILT11 ILT2 ILT3 ILT4 ILT5 ILT6 ILT7 ILT8 IREM1 IREM2 IREM3 ITGA4 ITGAL ITGB1 ITGB2 ITGB7 JAML KALI KAP10 KARAP KIR103AS KIR2DL1 KIR2DL2 KIR2DL3 KIR2DL4 KIR2DS1 KIR2DS2 KIR3DL1 KIR3DL2 KIRCL23 KLRB1 KLRC1 KLRD1 KLRF1 KLRG1 KLRK1 LAIR1 LAIR2 LETAL LILRA1 LILRA2 LILRA3 LILRA4 LILRA5 LILRA6 LILRB1 LILRB2 LILRB3 LILRB4 LILRB5 LILRB7 LIR1 LIR2 LIR3 LIR4 LIR5 LIR6 LIR7 LIR8 LIR9 LLT1 LMIR5 LNHR LW LY117 LY94 LY95 LYAM1 MAFA MAFAL MAL MDF2 MFI7 MIC2 MIC2X MIC2Y MICA MICB MIR10 MIR7 ML MOX1 MOX2 MOX2R MSK12 N2DL1 N2DL3 N2DL4 NCR1 NCR2 NCR3 NCR3LG1 NECTIN2 NKAT1 NKAT2 NKAT3 NKAT4 NKAT5 NKAT6 NKB1 NKG2A NKG2D NKIR NKRP1A NPDC1 NSR2 OBBP1 OBBP2 OCIL OSCAR OX2R PANP PERB11.1 PERB11.2 PIANP PIK3AP PILRA PILRB PRR2 PVR PVRL2 PVS RAET1E RAET1I RAET1N SAF2 SAP SCARA4 SELL SH2D1A SH2D1B SIGLEC1 SIGLEC10 SIGLEC11 SIGLEC12 SIGLEC2 SIGLEC3 SIGLEC5 SIGLEC6 SIGLEC7 SIGLEC8 SIGLEC9 SIGLECL1 SLAMF6 SLAMF7 SLG SLG2 SN SRCL T3D T3E T3G TAPA1 TCRA TCRBV12S3 TCRBV8S1 TLCN TLN TLT1 TLT2 TLT4 TNFSF5 TRAC TRAP TRAV19 TRAV29DV5 TRAV8-4 TRBC1 TRBV12-3 TRBV7-9 TREM1 TREM2 TREM4 TREM5 TREML1 TREML2 TREML4 TSPAN28 TYROBP UL83 ULBP1 ULBP3 ULBP4 UVO V1-11 V1-13 V1-16 V1-20 V1-3 V1-5 V1-7 V1-9 V2-11 V2-15 V2-17 V2-19 V2-8 V3-2 V3-3 V3-4 V4-1 V4-2 V4-6 V5-1 V5-4 V5-6 VCAM1 cd21
Imatinib-resistant PDGFR mutants	Platelet-derived growth factor receptor alpha	P16234	PDGFR2 PDGFRA RHEPDGFRA
Imatinib-resistant KIT mutants	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR
IkBA variant leads to EDA-ID	Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p100 subunit Nuclear factor NF-kappa-B p105 subunit Transcription factor p65	O14920 O15111 P19838 P25963 Q00653 Q04206 Q9Y6K9	CHUK FIP3 IKBA IKBKB IKBKG IKKA IKKB LYT10 MAD3 NEMO NFKB1 NFKB2 NFKB3 NFKBI NFKBIA RELA TCF16
ISG15 antiviral mechanism	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Aladin Antiviral innate immune response receptor RIG-I Beclin-1 E3 ISG15--protein ligase HERC5 E3 SUMO-protein ligase RanBP2 E3 ubiquitin-protein ligase ARIH1 E3 ubiquitin-protein ligase NEDD4 E3 ubiquitin/ISG15 ligase TRIM25 Eukaryotic initiation factor 4A-I Eukaryotic initiation factor 4A-II Eukaryotic initiation factor 4A-III Eukaryotic translation initiation factor 4 gamma 1 Eukaryotic translation initiation factor 4 gamma 2 Eukaryotic translation initiation factor 4 gamma 3 Eukaryotic translation initiation factor 4E type 2 Eukaryotic translation initiation factor 4E type 3 Eukaryotic translation initiation factor 4E Filamin-B Gag polyprotein Importin subunit alpha-1 Importin subunit alpha-3 Importin subunit alpha-4 Importin subunit alpha-5 Importin subunit alpha-6 Importin subunit alpha-8 Importin subunit beta-1 Interferon regulatory factor 3 Interferon-induced GTP-binding protein Mx1 Interferon-induced GTP-binding protein Mx2 Interferon-induced protein with tetratricopeptide repeats 1 Interferon-induced, double-stranded RNA-activated protein kinase Mitogen-activated protein kinase 3 Non-structural protein 1 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Polyubiquitin-B Polyubiquitin-C Protein SEC13 homolog Protein phosphatase 1B Signal transducer and activator of transcription 1-alpha/beta Tyrosine-protein kinase JAK1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 N Ubiquitin-like modifier-activating enzyme 7 Ubiquitin-like protein ISG15 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Ubiquitin/ISG15-conjugating enzyme E2 L6 Ubl carboxyl-terminal hydrolase 18 mRNA export factor RAE1	A8CG34 A9QM74 O00505 O00629 O14933 O15131 O15504 O43432 O60573 O75369 O75688 O75694 O95786 P03496 P05161 P06730 P09914 P0CG47 P0CG48 P12270 P12493 P19174 P19525 P20591 P20592 P23458 P27361 P35658 P37198 P38919 P41226 P42224 P46934 P49790 P49792 P51965 P52292 P52294 P55735 P57740 P60842 P61088 P62979 P62987 P78344 P78406 Q04637 Q12769 Q13526 Q14240 Q14258 Q14457 Q14653 Q14974 Q5SRE5 Q7Z3B4 Q8N1F7 Q8N5X7 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q96HA1 Q99567 Q9BTX1 Q9BW27 Q9NRG9 Q9UII4 Q9UKX7 Q9UMW8 Q9Y4X5	AAAS ADRACALA ARI ARIH1 BECN1 BLU C7orf14 CAIN CAN CEB1 CEBP1 CG1 D3S1231E DAP5 DDX2A DDX2B DDX48 DDX58 EFP EIF2AK2 EIF4A EIF4A1 EIF4A2 EIF4A3 EIF4E EIF4E2 EIF4E3 EIF4EL1 EIF4EL3 EIF4F EIF4G EIF4G1 EIF4G2 EIF4G3 EIF4GI ERK1 FLN1L FLN3 FLNB G10P1 G1P2 GT197 HERC5 IFI56 IFIT1 IFNAI1 IRF3 ISG15 ISG43 ISG56 JAK1 JAK1A JAK1B KIAA0023 KIAA0093 KIAA0095 KIAA0111 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 KPNA1 KPNA2 KPNA3 KPNA4 KPNA5 KPNA7 KPNB1 MAPK3 MOP6 MP44 MRNP41 MX1 MX2 NDC1 NEDD4 NEDD4-1 NPAP60L NS NTF97 NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PCNT1 PIN1 PKR PLC1 PLCG1 POM121 POM121A POM121C PP2CB PPM1B PRKM3 PRKR QIP1 QIP2 RAE1 RANBP2 RCH1 RCH2 RIGI RNF147 RPF1 RPS27A SEC13 SEC13A SEC13L1 SEC13R SRP1 STAT1 TABP TAP TMEM48 TPR TRIM25 UBA52 UBA7 UBA80 UBB UBC UBCEP1 UBCEP2 UBCH6 UBCH7BP UBCH8 UBE1L UBE2 UBE2E1 UBE2L6 UBE2N UCRP USP18 ZNF147 gag
IRS-related events triggered by IGF1R	Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor substrate 4 Insulin-like growth factor 1 receptor Insulin-like growth factor I Insulin-like growth factor II	O14654 P01344 P05019 P08069 P35568 Q9Y4H2	IBP1 IGF1 IGF1R IGF2 IRS1 IRS2 IRS4
IRS-mediated signalling	Insulin receptor substrate 1 Insulin receptor substrate 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	O00459 P27986 P35568 P42336 P42338 Q9Y4H2	GRB1 IRS1 IRS2 PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2
IRS activation	Growth factor receptor-bound protein 10 Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor Insulin	P01308 P06213 P35568 Q13322 Q9Y4H2	GRB10 GRBIR INS INSR IRS1 IRS2 KIAA0207
IRF3-mediated induction of type I IFN	DNA-dependent protein kinase catalytic subunit Double-strand break repair protein MRE11 E3 ubiquitin-protein ligase DTX4 Gamma-interferon-inducible protein 16 Interferon regulatory factor 3 NACHT, LRR and PYD domains-containing protein 4 NLR family CARD domain-containing protein 3 Probable ATP-dependent RNA helicase DDX41 Serine/threonine-protein kinase TBK1 Stimulator of interferon genes protein Three-prime repair exonuclease 1 X-ray repair cross-complementing protein 5 X-ray repair cross-complementing protein 6	P12956 P13010 P49959 P78527 Q14653 Q16666 Q7RTR2 Q86WV6 Q96MN2 Q9NSU2 Q9UHD2 Q9UJV9 Q9Y2E6	ABS DDX41 DTX4 ERIS G22P1 G22P2 HNGS1 HYRC HYRC1 IFI16 IFNGIP1 IRF3 KIAA0937 MITA MRE11 MRE11A NAK NALP4 NLRC3 NLRP4 NOD3 PAN2 PRKDC PYPAF4 RNF155 RNH2 STING STING1 TBK1 TMEM173 TREX1 XRCC5 XRCC6
IRF3 mediated activation of type 1 IFN	E3 ubiquitin-protein ligase DTX4 Interferon regulatory factor 3 NACHT, LRR and PYD domains-containing protein 4 Serine/threonine-protein kinase TBK1 Z-DNA-binding protein 1	Q14653 Q96MN2 Q9H171 Q9UHD2 Q9Y2E6	C20orf183 DLM1 DTX4 IRF3 KIAA0937 NAK NALP4 NLRP4 PAN2 PYPAF4 RNF155 RNH2 TBK1 ZBP1
IRE1alpha activates chaperones	Endoplasmic reticulum chaperone BiP Serine/threonine-protein kinase/endoribonuclease IRE1	O75460 P11021	ERN1 GRP78 HSPA5 IRE1
IRAK4 deficiency (TLR5)	Flagellin Interleukin-1 receptor-associated kinase 4 Myeloid differentiation primary response protein MyD88 Toll-like receptor 10 Toll-like receptor 5	O60602 P04949 Q99836 Q9BXR5 Q9NWZ3	IRAK4 MYD88 TIL3 TLR10 TLR5 flaF fliC hag
IRAK4 deficiency (TLR2/4)	Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain High mobility group protein B1 Interleukin-1 receptor-associated kinase 4 Lymphocyte antigen 96 Major outer membrane protein P.IB Monocyte differentiation antigen CD14 Myeloid differentiation primary response protein MyD88 Peptidyl-prolyl cis-trans isomerase Mip Platelet glycoprotein 4 Protein S100-A1 Protein S100-A8 Protein S100-A9 Toll-like receptor 1 Toll-like receptor 2 Toll-like receptor 4 Toll-like receptor 6 Toll/interleukin-1 receptor domain-containing adapter protein Tyrosine-protein kinase BTK	O00206 O60603 P02671 P02675 P02679 P05109 P06702 P08571 P09429 P16671 P23297 P26623 P30690 P58753 Q06187 Q15399 Q99836 Q9NWZ3 Q9Y2C9 Q9Y6Y9	AGMX1 ATK BPK BTK CAGA CAGB CD14 CD36 CFAG ESOP1 FGA FGB FGG GP3B GP4 HMG1 HMGB1 IRAK4 KIAA0012 LY96 MAL MD2 MRP14 MRP8 MYD88 S100A S100A1 S100A8 S100A9 TIL4 TIRAP TLR1 TLR2 TLR4 TLR6 mip porB
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	Interleukin-1 receptor-associated kinase-like 2 Lymphocyte antigen 96 Mitogen-activated protein kinase kinase kinase 7 Monocyte differentiation antigen CD14 Polyubiquitin-B Polyubiquitin-C TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 TNF receptor-associated factor 6 Toll-like receptor 4 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00206 O43187 O43318 P08571 P0CG47 P0CG48 P62979 P62987 Q15750 Q86XR7 Q8IUC6 Q8N5C8 Q9NYJ8 Q9Y4K3 Q9Y6Y9	CD14 ESOP1 IRAK2 KIAA0733 LY96 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MD2 PRVTIRB RNF85 RPS27A TAB1 TAB2 TAB3 TAK1 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAF6 TRAM TRIF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
IRAK2 mediated activation of TAK1 complex	Interleukin-1 receptor-associated kinase-like 2 Mitogen-activated protein kinase kinase kinase 7 Polyubiquitin-B Polyubiquitin-C TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 6 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O43187 O43318 P0CG47 P0CG48 P62979 P62987 Q15750 Q8N5C8 Q9NYJ8 Q9Y4K3	IRAK2 KIAA0733 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 RNF85 RPS27A TAB1 TAB2 TAB3 TAK1 TRAF6 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation	E3 ubiquitin-protein ligase pellino homolog 1 E3 ubiquitin-protein ligase pellino homolog 2 E3 ubiquitin-protein ligase pellino homolog 3 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 receptor-associated kinase 1 NF-kappa-B essential modulator TNF receptor-associated factor 6 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1	O14920 O15111 P51617 P61088 Q13404 Q8N2H9 Q96FA3 Q9HAT8 Q9Y4K3 Q9Y6K9	BLU CHUK CROC1 FIP3 IKBKB IKBKG IKKA IKKB IRAK IRAK1 NEMO PELI1 PELI2 PELI3 PRISM RNF85 TCF16 TRAF6 UBE2N UBE2V UBE2V1 UEV1
IRAK1 recruits IKK complex	E3 ubiquitin-protein ligase pellino homolog 1 E3 ubiquitin-protein ligase pellino homolog 2 E3 ubiquitin-protein ligase pellino homolog 3 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 receptor-associated kinase 1 NF-kappa-B essential modulator TNF receptor-associated factor 6 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1	O14920 O15111 P51617 P61088 Q13404 Q8N2H9 Q96FA3 Q9HAT8 Q9Y4K3 Q9Y6K9	BLU CHUK CROC1 FIP3 IKBKB IKBKG IKKA IKKB IRAK IRAK1 NEMO PELI1 PELI2 PELI3 PRISM RNF85 TCF16 TRAF6 UBE2N UBE2V UBE2V1 UEV1

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