GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **1676 - 1700** of **2090** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol
Serotonin and melatonin biosynthesis	Acetylserotonin O-methyltransferase Aromatic-L-amino-acid decarboxylase Serotonin N-acetyltransferase Tryptophan 5-hydroxylase 1 Tryptophan 5-hydroxylase 2	P17752 P20711 P46597 Q16613 Q8IWU9	AADC AANAT ASMT DDC NTPH SNAT TPH TPH1 TPH2 TPRH TRPH
Serotonin receptors	5-hydroxytryptamine receptor 1A 5-hydroxytryptamine receptor 1B 5-hydroxytryptamine receptor 1D 5-hydroxytryptamine receptor 1E 5-hydroxytryptamine receptor 1F 5-hydroxytryptamine receptor 2A 5-hydroxytryptamine receptor 2B 5-hydroxytryptamine receptor 2C 5-hydroxytryptamine receptor 4 5-hydroxytryptamine receptor 5A 5-hydroxytryptamine receptor 6 5-hydroxytryptamine receptor 7	P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P47898 P50406 Q13639	ADRB2RL1 ADRBRL1 HTR1A HTR1B HTR1C HTR1D HTR1DA HTR1DB HTR1E HTR1EL HTR1F HTR2 HTR2A HTR2B HTR2C HTR4 HTR5A HTR6 HTR7 HTRL
Sialic acid metabolism	Alpha-2,8-sialyltransferase 8B Alpha-2,8-sialyltransferase 8E Alpha-2,8-sialyltransferase 8F Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase ST8SIA3 Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase Beta-galactosidase Beta-galactoside alpha-2,6-sialyltransferase 1 Beta-galactoside alpha-2,6-sialyltransferase 2 Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase CMP-sialic acid transporter Lactosylceramide alpha-2,3-sialyltransferase Lysosomal protective protein N-acetylneuraminate lyase N-acylneuraminate cytidylyltransferase N-acylneuraminate-9-phosphatase Sialic acid synthase Sialidase-1 Sialidase-2 Sialidase-3 Sialidase-4 Sialin Type 2 lactosamine alpha-2,3-sialyltransferase	O15466 O43173 P10619 P15907 P16278 P61647 P78382 Q11201 Q11203 Q11206 Q16842 Q8NDV1 Q8NFW8 Q8TBE9 Q8WWR8 Q92185 Q92186 Q92187 Q969X2 Q96JF0 Q99519 Q9BVH7 Q9BXD5 Q9H4F1 Q9NR45 Q9NRA2 Q9NSC7 Q9UJ37 Q9UNP4 Q9UQ49 Q9Y223 Q9Y274 Q9Y3R4	C1orf13 C20orf147 CGS23 CMAS CTSA ELNR1 GLB1 GLCNE GNE HDHD4 IBM2 KIAA1877 NANH NANP NANS NANTA3 NEU1 NEU2 NEU3 NEU4 NPL PPGB PST PST1 SAS SIAT1 SIAT10 SIAT2 SIAT3C SIAT4 SIAT4A SIAT4B SIAT4C SIAT6 SIAT7A SIAT7B SIAT7C SIAT7D SIAT7E SIAT7F SIAT8 SIAT8A SIAT8B SIAT8C SIAT8D SIAT8E SIAT8F SIAT9 SIATL1 SLC17A5 SLC35A1 ST3GAL1 ST3GAL2 ST3GAL3 ST3GAL4 ST3GAL5 ST3GAL6 ST6GAL1 ST6GAL2 ST6GALNAC1 ST6GALNAC2 ST6GALNAC3 ST6GALNAC4 ST6GALNAC5 ST6GALNAC6 ST8SIA1 ST8SIA2 ST8SIA3 ST8SIA4 ST8SIA5 ST8SIA6 STHM STX STZ
Signal attenuation	Growth factor receptor-bound protein 10 Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor Insulin Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 SHC-transforming protein 1 Son of sevenless homolog 1	P01308 P06213 P27361 P28482 P29353 P35568 Q07889 Q13322 Q9Y4H2	ERK1 ERK2 GRB10 GRBIR INS INSR IRS1 IRS2 KIAA0207 MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 SHC SHC1 SHCA SOS1
Signal regulatory protein family interactions	FYN-binding protein 1 Focal adhesion kinase 1 Leukocyte surface antigen CD47 Protein-tyrosine kinase 2-beta Signal-regulatory protein beta-1 Signal-regulatory protein gamma Src kinase-associated phosphoprotein 2 TYRO protein tyrosine kinase-binding protein Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6 Tyrosine-protein phosphatase non-receptor type substrate 1	O00241 O15117 O43914 O75563 P29350 P78324 Q05397 Q06124 Q08722 Q14289 Q9P1W8	BIT CD47 DAP12 FAK FAK1 FAK2 FYB FYB1 HCP KARAP MER6 MFR MYD1 PRAP PTK2 PTK2B PTP1C PTP2C PTPN11 PTPN6 PTPNS1 PYK2 RA70 RAFTK SAPS SCAP2 SHPS1 SHPTP2 SIRP SIRPA SIRPB1 SIRPB2 SIRPG SKAP2 SKAP55R SLAP130 TYROBP
Signal transduction by L1	Casein kinase II subunit alpha' Casein kinase II subunit alpha Casein kinase II subunit beta Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Epidermal growth factor receptor Guanine nucleotide exchange factor VAV2 Integrin alpha-5 Integrin alpha-9 Integrin alpha-IIb Integrin alpha-V Integrin beta-1 Integrin beta-3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Neural cell adhesion molecule 1 Neural cell adhesion molecule L1 Neuropilin-1 Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 1	O14786 P00533 P05106 P05556 P06756 P08514 P08648 P13591 P19784 P27361 P28482 P32004 P36507 P52735 P63000 P67870 P68400 Q02750 Q13153 Q13797	CAML1 CK2A1 CK2A2 CK2N CSNK2A1 CSNK2A2 CSNK2B EGFR ERBB ERBB1 ERK1 ERK2 FNRA FNRB G5A GP2B GP3A HER1 ITGA2B ITGA5 ITGA9 ITGAB ITGAV ITGB1 ITGB3 L1CAM MAP2K1 MAP2K2 MAPK1 MAPK3 MDF2 MEK1 MEK2 MIC5 MKK2 MSK12 MSK8 NCAM NCAM1 NRP NRP1 PAK1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 RAC1 TC25 VAV2 VEGF165R VNRA VTNR
Signaling by ALK	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 ALK and LTK ligand 1 ALK and LTK ligand 2 ALK tyrosine kinase receptor Fibroblast growth factor receptor substrate 2 Insulin receptor substrate 1 Midkine Myc proto-oncogene protein N-myc proto-oncogene protein Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Pleiotrophin Signal transducer and activator of transcription 3 Tyrosine-protein kinase JAK3 Tyrosine-protein phosphatase non-receptor type 6	O00459 P01106 P04198 P19174 P21246 P21741 P27986 P29350 P35568 P40763 P42336 P42338 P52333 Q6UX46 Q6UXT8 Q8WU20 Q9UM73	ALK ALKAL1 ALKAL2 APRF BHLHE37 BHLHE39 FAM150A FAM150B FRS2 GRB1 HBNF1 HCP IRS1 JAK3 MDK MK1 MYC MYCN NEGF1 NEGF2 NMYC PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 PLC1 PLCG1 PTN PTP1C PTPN6 STAT3
Signaling by ALK fusions and activated point mutants	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 ALK tyrosine kinase receptor B-cell lymphoma/leukemia 11A Baculoviral IAP repeat-containing protein 6 Bifunctional purine biosynthesis protein ATIC Cellular tumor antigen p53 Clathrin heavy chain 1 Cyclin-dependent kinase inhibitor 1 Cysteine--tRNA ligase, cytoplasmic Dynactin subunit 1 E3 SUMO-protein ligase RanBP2 E3 ubiquitin-protein ligase Mdm2 E3 ubiquitin-protein ligase RNF213 Echinoderm microtubule-associated protein-like 4 Elongation factor 1-gamma Eukaryotic translation initiation factor 2-alpha kinase 3 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 Fibronectin GRIP and coiled-coil domain-containing protein 2 Growth factor receptor-bound protein 2 Huntingtin-interacting protein 1 Induced myeloid leukemia cell differentiation protein Mcl-1 Insulin receptor substrate 1 Interleukin-10 Interleukin-22 Kinesin light chain 1 Kinesin-1 heavy chain LIM domain only protein 7 Liprin-beta-1 Mitogen-activated protein kinase 8 Mitogen-activated protein kinase 9 Moesin Myosin-9 Non-receptor tyrosine-protein kinase TYK2 Nucleophosmin Nucleoprotein TPR Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Polyubiquitin-B Polyubiquitin-C Protein TFG Protein phosphatase 1B Protein transport protein Sec31A Ribosome-binding protein 1 Sequestosome-1 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Striatin Transcription factor Jun Tropomyosin alpha-3 chain Tropomyosin alpha-4 chain Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Vinculin WD repeat and coiled-coil-containing protein cAMP-dependent protein kinase type I-alpha regulatory subunit	O00291 O00459 O43559 O43815 O75688 O94979 P02751 P04637 P05412 P06748 P06753 P0CG47 P0CG48 P10644 P12270 P18206 P19174 P22301 P26038 P26641 P27986 P29597 P31939 P33176 P35568 P35579 P38936 P40763 P42224 P42336 P42338 P45983 P45984 P49589 P49792 P62979 P62987 P62993 P67936 Q00610 Q00987 Q07820 Q07866 Q13501 Q14203 Q63HN8 Q86W92 Q8IWJ2 Q8WU20 Q8WWI1 Q92734 Q9GZX6 Q9H165 Q9H6R7 Q9HC35 Q9NR09 Q9NZJ5 Q9P2E9 Q9UM73	ALK ALO17 APRF ASH ATIC BCL11A BCL2L3 BIRC6 C17orf27 C2orf2 C2orf44 CAP20 CARS CARS1 CDKN1 CDKN1A CIP1 CLH17 CLTC CLTCL2 CTIP1 DCTN1 EEF1G EF1G EIF2AK3 EMAPL4 EML4 EVI9 FBX20 FBXO20 FN FN1 FRS2 FRS3 GCC2 GRB1 GRB2 HIP1 IL10 IL22 ILTIF IRS1 JNK1 JNK2 JUN KIAA0034 KIAA0336 KIAA0858 KIAA0905 KIAA1230 KIAA1289 KIAA1398 KIAA1554 KIAA1618 KIAA1809 KIF5B KLC KLC1 KNS KNS1 KNS2 LMO7 MAPK8 MAPK9 MCL1 MDA6 MDM2 MSN MYH9 MYSTR NPM NPM1 NUP358 ORCA OSIL P53 PEK PERK PIC1 PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 PKR1 PLC1 PLCG1 PP2CB PPFIBP1 PPM1B PRKAR1 PRKAR1A PRKM8 PRKM9 PURH RANBP2 RANBP2L4 RNF213 RPS27A RRBP1 SAPK1 SAPK1A SAPK1C SDI1 SEC31A SEC31L1 SQSTM1 STAT1 STAT3 STRN TFG TP53 TPM3 TPM4 TPR TSE1 TYK2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VCL WAF1 WDCP ZCYTO18 ZNF856
Signaling by Activin	Activin receptor type-1B Activin receptor type-1C Activin receptor type-2A Activin receptor type-2B Dr1-associated corepressor Forkhead box protein H1 Inhibin alpha chain Inhibin beta A chain Inhibin beta B chain Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Transforming growth factor beta receptor type 3	O75593 P05111 P08476 P09529 P27037 P27361 P28482 P36896 P84022 Q03167 Q13485 Q13705 Q14919 Q15796 Q8NER5	ACVR1B ACVR1C ACVR2 ACVR2A ACVR2B ACVRLK4 ALK4 ALK7 DPC4 DRAP1 ERK1 ERK2 FAST1 FAST2 FOXH1 INHA INHBA INHBB MADH2 MADH3 MADH4 MADR2 MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 SMAD2 SMAD3 SMAD4 TGFBR3
Signaling by BMP	Activin receptor type-2A Activin receptor type-2B Anti-Muellerian hormone type-2 receptor Bone morphogenetic protein 10 Bone morphogenetic protein 2 Bone morphogenetic protein receptor type-1A Bone morphogenetic protein receptor type-1B Bone morphogenetic protein receptor type-2 Cerberus Chordin-like protein 1 E3 ubiquitin-protein ligase SMURF1 E3 ubiquitin-protein ligase SMURF2 Follistatin-related protein 1 Gremlin-2 Growth/differentiation factor 2 Inhibin alpha chain Inhibin beta A chain Mothers against decapentaplegic homolog 1 Mothers against decapentaplegic homolog 4 Mothers against decapentaplegic homolog 5 Mothers against decapentaplegic homolog 6 Mothers against decapentaplegic homolog 7 Mothers against decapentaplegic homolog 9 Muellerian-inhibiting factor Noggin Serine/threonine-protein kinase receptor R3 Ski oncogene Transforming growth factor beta receptor type 3 Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D3 Zinc finger FYVE domain-containing protein 16	O00238 O15105 O15198 O43541 O95393 O95813 P03971 P05111 P08476 P12643 P12755 P27037 P36894 P37023 P51668 P61077 Q03167 Q12841 Q13253 Q13485 Q13705 Q13873 Q15797 Q16671 Q7Z3T8 Q99717 Q9BU40 Q9H772 Q9HAU4 Q9HCE7 Q9UK05	ACVR2 ACVR2A ACVR2B ACVRL1 ACVRLK1 ACVRLK3 ALK1 ALK3 AMH AMHR AMHR2 BMP10 BMP2 BMP2A BMP9 BMPR1A BMPR1B BMPR2 BSP1 CER1 CHRDL1 CKTSF1B2 DAND3 DAND4 DPC4 FRP FSTL1 GDF2 GREM2 INHA INHBA KIAA0305 KIAA1625 MADH1 MADH4 MADH5 MADH6 MADH7 MADH8 MADH9 MADR1 MIF MISR2 NOG NRLN1 PPH1 PRDC SFT SKI SMAD1 SMAD4 SMAD5 SMAD6 SMAD7 SMAD8 SMAD9 SMURF1 SMURF2 TGFBR3 UBC5A UBC5C UBCH5 UBCH5A UBCH5C UBE2D1 UBE2D3 ZFYVE16
Signaling by BRAF and RAF1 fusions	14-3-3 protein beta/alpha A-kinase anchor protein 9 AP-3 complex subunit beta-1 Acylglycerol kinase, mitochondrial Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Angiogenic factor with G patch and FHA domains 1 Bcl-2-like protein 11 Beta-arrestin-1 Beta-arrestin-2 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Connector enhancer of kinase suppressor of ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Epithelial splicing regulatory protein 1 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase NRas H(+)/Cl(-) exchange transporter 6 Integrin alpha-IIb Integrin beta-3 KH domain-containing RNA-binding protein QKI Kinase suppressor of Ras 1 Kinase suppressor of Ras 2 Lysine-specific demethylase 7A MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Myosin phosphatase Rho-interacting protein Phosphatidylethanolamine-binding protein 1 Prelamin-A/C Protein FAM114A2 Protein FAM131B Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase RNA-binding protein FXR1 Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A Ras-related protein Rap-1b Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Staphylococcal nuclease domain-containing protein 1 Talin-1 Terminal nucleotidyltransferase 4A Trafficking kinesin-binding protein 1 Transcription intermediary factor 1-alpha Type-1 angiotensin II receptor-associated protein Tyrosine-protein kinase CSK Tyrosine-protein kinase JAK2 UPF0606 protein KIAA1549 Ubiquitin-like modifier-activating enzyme ATG7 Vinculin Zinc finger CCCH-type antiviral protein 1 von Willebrand factor	O00203 O15164 O43252 O43521 O60674 O95352 P01111 P01112 P02545 P02671 P02675 P02679 P02751 P04049 P04275 P05106 P08514 P0DP23 P10398 P12931 P15056 P18206 P27361 P27448 P28482 P30086 P31946 P32121 P36507 P41240 P46940 P49407 P51114 P51797 P61224 P62834 Q02750 Q13554 Q13555 Q13557 Q53H12 Q5XG87 Q6NXG1 Q6RW13 Q6VAB6 Q6WCQ1 Q6ZMT4 Q7KZF4 Q7Z2W4 Q7Z5R6 Q86XD5 Q8IVT5 Q8N302 Q8WXI2 Q969H4 Q96PU8 Q99996 Q9HCM3 Q9NRY5 Q9UPV9 Q9UQM7 Q9Y490	ADTB3A AGGF1 AGK AGTRAP AKAP350 AKAP450 AKAP9 AP3B1 APBB1IP APG7L ARAF ARAF1 ARB2 ARR1 ARR2 ARRB1 ARRB2 ATG7 ATPSK1 ATRAP BCL2L11 BIM BRAF BRAF1 C5orf3 CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CLCN6 CNK1 CNK2 CNKSR1 CNKSR2 CSK CTAK1 EMK2 ERK1 ERK2 ESRP1 F8VWF FAM114A2 FAM131B FGA FGB FGG FN FN1 FXR1 GP2B GP3A GPATC7 GPATCH7 HKQ HRAS HRAS1 IQGAP1 ITGA2B ITGAB ITGB3 JAK2 JHDM1D KDM7 KDM7A KIAA0046 KIAA0051 KIAA0773 KIAA0803 KIAA0864 KIAA0902 KIAA0968 KIAA1027 KIAA1042 KIAA1549 KIAA1718 KREV1 KSR KSR1 KSR2 LMN1 LMNA MAP2K1 MAP2K2 MAPK1 MAPK3 MARK3 MEK1 MEK2 MKK2 MPRIP MRIP MULK NRAS OIP106 PAPD7 PAPSS PAPSS1 PBP PEBP PEBP1 PKS PKS2 POLS PREL1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 QKI RAF RAF1 RAFB1 RAP1A RAP1B RARP1 RBM35A RHOIP3 RIAM RNF82 SND1 SRC SRC1 TDRD11 TENT4A TIF1 TIF1A TLN TLN1 TRAK1 TRF4 TRIM24 VCL VG5Q VWF YWHAB ZC3HAV1 ZC3HDC2
Signaling by CSF1 (M-CSF) in myeloid cells	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 E3 ubiquitin-protein ligase CBL GRB2-associated-binding protein 2 GRB2-associated-binding protein 3 GRB2-related adapter protein 2 GTPase KRas Interleukin-34 Macrophage colony-stimulating factor 1 receptor Macrophage colony-stimulating factor 1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Polyubiquitin-B Polyubiquitin-C Proto-oncogene tyrosine-protein kinase Src SHC-transforming protein 1 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Son of sevenless homolog 1 THO complex subunit 5 homolog Tyrosine-protein kinase Fyn Tyrosine-protein kinase HCK Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00329 O15357 O75791 P01116 P06241 P07333 P07947 P07948 P08631 P09603 P0CG47 P0CG48 P12931 P16885 P22681 P27986 P29353 P40763 P42224 P42336 P42338 P62979 P62987 Q06124 Q07889 Q13769 Q6ZMJ4 Q8WWW8 Q92835 Q9UQC2	APRF C16orf77 C22orf19 CBL CBL2 CSF1 CSF1R FMS FYN GAB2 GAB3 GADS GRAP2 GRB1 GRB2L GRID HCK IL34 INPP5D INPPL1 JTK8 KIAA0571 KIAA0983 KRAS KRAS2 LYN PIK3C1 PIK3CA PIK3CB PIK3CD PIK3R1 PLCG2 PTP2C PTPN11 RASK2 RNF55 RPS27A SHC SHC1 SHCA SHIP SHIP1 SHIP2 SHPTP2 SOS1 SRC SRC1 STAT1 STAT3 THOC5 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 YES YES1
Signaling by CSF3 (G-CSF)	GRB2-associated-binding protein 2 GTPase KRas Granulocyte colony-stimulating factor receptor Granulocyte colony-stimulating factor Growth factor receptor-bound protein 2 Non-receptor tyrosine-protein kinase TYK2 SHC-transforming protein 1 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase HCK Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Tyrosine-protein phosphatase non-receptor type 11	O14543 O15524 O60674 P01116 P07948 P08631 P09919 P23458 P29353 P29597 P40763 P42224 P42229 P43405 P51692 P62993 Q06124 Q99062 Q9UQC2	APRF ASH C17orf33 CIS3 CSF3 CSF3R GAB2 GCSF GCSFR GRB2 HCK JAK1 JAK1A JAK1B JAK2 JTK8 KIAA0571 KRAS KRAS2 LYN PTP2C PTPN11 RASK2 SHC SHC1 SHCA SHPTP2 SOCS1 SOCS3 SSI1 SSI3 STAT1 STAT3 STAT5 STAT5A STAT5B SYK TIP3 TYK2
Signaling by EGFR	Amphiregulin Angio-associated migratory cell protein Disintegrin and metalloproteinase domain-containing protein 10 Disintegrin and metalloproteinase domain-containing protein 12 Disintegrin and metalloproteinase domain-containing protein 17 Epidermal growth factor receptor Epigen Leucine-rich repeats and immunoglobulin-like domains protein 1 Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protein FAM83A Protein FAM83B Protein FAM83D Protransforming growth factor alpha	O14672 O14944 O43184 P00533 P01133 P01135 P15514 P35070 P78536 Q13685 Q5T0W9 Q6UW88 Q86UY5 Q96JA1 Q99075 Q9H4H8	AAMP ADAM10 ADAM12 ADAM17 AREG AREGB BTC C20orf129 C6orf143 CSVP DTR DTS EGF EGFR EPGN ERBB ERBB1 EREG FAM83A FAM83B FAM83D HBEGF HEGFL HER1 KUZ LIG1 LRIG1 MADM MLTN SDGF TACE TGFA TSGP
Signaling by ERBB2	Epidermal growth factor receptor Erbin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase Src Receptor tyrosine-protein kinase erbB-2 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Yes	O14511 O14944 P00533 P01133 P04626 P06241 P07900 P07947 P12931 P35070 P56975 Q02297 Q16543 Q8WWG1 Q96RT1 Q99075	BTC CDC37 CDC37A DTR DTS EGF EGFR ERBB ERBB1 ERBB2 ERBB2IP ERBIN EREG FYN GGF HBEGF HEGFL HER1 HER2 HGL HRGA HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NDF NEU NGL NRG1 NRG2 NRG3 NRG4 NTAK SMDF SRC SRC1 YES YES1
Signaling by ERBB2 ECD mutants	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Epidermal growth factor receptor Erbin GRB2-associated-binding protein 1 GTPase HRas GTPase NRas Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Pro-epidermal growth factor Receptor tyrosine-protein kinase erbB-2 SHC-transforming protein 1 Son of sevenless homolog 1	P00533 P01111 P01112 P01133 P04626 P07900 P19174 P27986 P29353 P42336 Q07889 Q13480 Q16543 Q96RT1	CDC37 CDC37A EGF EGFR ERBB ERBB1 ERBB2 ERBB2IP ERBIN GAB1 GRB1 HER1 HER2 HRAS HRAS1 HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NEU NGL NRAS PIK3CA PIK3R1 PLC1 PLCG1 SHC SHC1 SHCA SOS1
Signaling by ERBB2 KD Mutants	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Epidermal growth factor receptor Erbin GRB2-associated-binding protein 1 GTPase HRas GTPase NRas Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Receptor tyrosine-protein kinase erbB-2 SHC-transforming protein 1 Son of sevenless homolog 1	O14511 O14944 P00533 P01111 P01112 P01133 P04626 P07900 P19174 P27986 P29353 P35070 P42336 P56975 Q02297 Q07889 Q13480 Q16543 Q8WWG1 Q96RT1 Q99075	BTC CDC37 CDC37A DTR DTS EGF EGFR ERBB ERBB1 ERBB2 ERBB2IP ERBIN EREG GAB1 GGF GRB1 HBEGF HEGFL HER1 HER2 HGL HRAS HRAS1 HRGA HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NDF NEU NGL NRAS NRG1 NRG2 NRG3 NRG4 NTAK PIK3CA PIK3R1 PLC1 PLCG1 SHC SHC1 SHCA SMDF SOS1
Signaling by ERBB2 TMD/JMD mutants	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Epidermal growth factor receptor Erbin GTPase HRas GTPase NRas Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Receptor tyrosine-protein kinase erbB-2 SHC-transforming protein 1 Son of sevenless homolog 1	O14511 O14944 P00533 P01111 P01112 P01133 P04626 P07900 P19174 P29353 P35070 P56975 Q02297 Q07889 Q16543 Q8WWG1 Q96RT1 Q99075	BTC CDC37 CDC37A DTR DTS EGF EGFR ERBB ERBB1 ERBB2 ERBB2IP ERBIN EREG GGF HBEGF HEGFL HER1 HER2 HGL HRAS HRAS1 HRGA HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NDF NEU NGL NRAS NRG1 NRG2 NRG3 NRG4 NTAK PLC1 PLCG1 SHC SHC1 SHCA SMDF SOS1
Signaling by ERBB4	Disks large homolog 4 Epidermal growth factor receptor Gamma-aminobutyric acid receptor subunit alpha-1 Gamma-aminobutyric acid receptor subunit beta-1 Gamma-aminobutyric acid receptor subunit beta-2 Gamma-aminobutyric acid receptor subunit beta-3 Gamma-aminobutyric acid receptor subunit gamma-2 Gamma-aminobutyric acid receptor subunit gamma-3 Gamma-aminobutyric acid receptor subunit theta Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor	O14511 O14944 P00533 P01133 P14867 P18505 P18507 P28472 P35070 P47870 P56975 P78352 Q02297 Q8WWG1 Q99075 Q99928 Q9UN88	BTC DLG4 DTR DTS EGF EGFR ERBB ERBB1 EREG GABRA1 GABRB1 GABRB2 GABRB3 GABRG2 GABRG3 GABRQ GGF HBEGF HEGFL HER1 HGL HRGA NDF NRG1 NRG2 NRG3 NRG4 NTAK PSD95 SMDF
Signaling by Erythropoietin	Erythropoietin receptor Erythropoietin Insulin receptor substrate 2 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn	O60674 P01588 P07948 P19235 Q9Y4H2	EPO EPOR IRS2 JAK2 JTK8 LYN
Signaling by FGFR1 in disease	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 BAG family molecular chaperone regulator 4 Breakpoint cluster region protein Centrosomal protein 43 Cleavage and polyadenylation specificity factor subunit 6 Erlin-2 FGFR1 oncogene partner 2 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor 1 Fibroblast growth factor receptor substrate 2 GRB2-associated-binding protein 1 GTPase HRas GTPase NRas Homeobox protein cut-like 1 Leucine-rich repeat flightless-interacting protein 1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Son of sevenless homolog 1 Transcription intermediary factor 1-alpha Unconventional myosin-XVIIIa Zinc finger MYM-type protein 2	O15164 O94905 O95429 O95684 P01111 P01112 P05230 P08620 P09038 P10767 P11274 P11362 P19174 P27986 P31371 P39880 P42336 Q07889 Q13480 Q16630 Q32MZ4 Q8WU20 Q92614 Q9GZV9 Q9NP95 Q9NVK5 Q9UBW7	BAG4 BCR BCR1 BFGFR C8orf2 CD245 CEK CEP43 CFIM68 CPSF6 CUTL1 CUX1 D22S11 ERLIN2 FGF1 FGF2 FGF20 FGF23 FGF4 FGF6 FGF9 FGFA FGFB FGFBR FGFR1 FGFR1OP FGFR1OP2 FIM FLG FLT2 FOP FRS2 GAB1 GCF2 GRB1 HBGFR HRAS HRAS1 HST HST2 HSTF1 HSTF2 HYPF KIAA0216 KS3 LRRFIP1 MYO18A MYSPDZ NRAS PIK3CA PIK3R1 PLC1 PLCG1 RAMP RNF82 SODD SOS1 SPFH2 TIAF1 TIF1 TIF1A TRIM24 TRIP ZMYM2 ZNF198
Signaling by FGFR2 IIIa TM	DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor receptor 2 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2	O15514 P05230 P09038 P13984 P19387 P19388 P21802 P24928 P30876 P35269 P36954 P52298 P52434 P52435 P53803 P61218 P62487 P62875 Q09161	BEK CBP20 CBP80 FGF1 FGF2 FGFA FGFB FGFR2 GTF2F1 GTF2F2 KGFR KSAM NCBP NCBP1 NCBP2 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RPB7
Signaling by FGFR2 amplification mutants	Fibroblast growth factor receptor 2	P21802	BEK FGFR2 KGFR KSAM
Signaling by FGFR2 fusions	Fibroblast growth factor receptor 2	P21802	BEK FGFR2 KGFR KSAM
Signaling by FGFR2 in disease	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor 2 Fibroblast growth factor receptor substrate 2 GRB2-associated-binding protein 1 GTPase HRas GTPase NRas Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Son of sevenless homolog 1	O15520 O43320 O76093 P01111 P01112 P05230 P08620 P09038 P10767 P11487 P19174 P21781 P21802 P27986 P31371 P42336 Q07889 Q13480 Q8WU20 Q9GZV9 Q9HCT0 Q9NP95	BEK FGF1 FGF10 FGF16 FGF18 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB FGFR2 FRS2 GAB1 GRB1 HRAS HRAS1 HST HST2 HSTF1 HSTF2 HYPF INT2 KGF KGFR KS3 KSAM NRAS PIK3CA PIK3R1 PLC1 PLCG1 SOS1

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