GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **151 - 175** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲
Pyruvate metabolism	Alanine aminotransferase 1 L-lactate dehydrogenase A chain L-lactate dehydrogenase A-like 6A L-lactate dehydrogenase A-like 6B L-lactate dehydrogenase B chain L-lactate dehydrogenase C chain Lactoylglutathione lyase Mitochondrial pyruvate carrier 1-like protein Mitochondrial pyruvate carrier 1 Mitochondrial pyruvate carrier 2 NAD-dependent malic enzyme, mitochondrial NADP-dependent malic enzyme, mitochondrial NADP-dependent malic enzyme Oxaloacetate decarboxylase, mitochondrial Pyruvate carboxylase, mitochondrial Voltage-dependent anion-selective channel protein 1	O95563 P00338 P07195 P07864 P0DKB6 P11498 P21796 P23368 P24298 P48163 Q04760 Q16798 Q6P587 Q6ZMR3 Q9BYZ2 Q9Y5U8	AAT1 BRP44 BRP44L C16orf36 FAHD1 GLO1 GPT GPT1 LDH3 LDHA LDHAL6 LDHAL6A LDHAL6B LDHB LDHC LDHL LDHL2 LDHX ME1 ME2 ME3 MPC1 MPC1L MPC2 PC VDAC VDAC1 YISKL
NRAGE signals death through JNK	A-kinase anchor protein 13 Active breakpoint cluster region-related protein Bcl-2-like protein 11 Bcl2-associated agonist of cell death Beta-nerve growth factor Ephexin-1 FYVE, RhoGEF and PH domain-containing protein 1 FYVE, RhoGEF and PH domain-containing protein 2 FYVE, RhoGEF and PH domain-containing protein 3 FYVE, RhoGEF and PH domain-containing protein 4 Guanine nucleotide exchange factor DBS Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Guanine nucleotide-binding protein subunit alpha-13 Intersectin-1 Kalirin Melanoma-associated antigen D1 Mitogen-activated protein kinase 8 Neuroepithelial cell-transforming gene 1 protein Obscurin Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Pleckstrin homology domain-containing family G member 2 Pleckstrin homology domain-containing family G member 5 Protein AATF Protein ECT2 Proto-oncogene DBL Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Ras-specific guanine nucleotide-releasing factor 2 Rho guanine nucleotide exchange factor 10-like protein Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 16 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 18 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 26 Rho guanine nucleotide exchange factor 2 Rho guanine nucleotide exchange factor 33 Rho guanine nucleotide exchange factor 35 Rho guanine nucleotide exchange factor 37 Rho guanine nucleotide exchange factor 38 Rho guanine nucleotide exchange factor 39 Rho guanine nucleotide exchange factor 3 Rho guanine nucleotide exchange factor 40 Rho guanine nucleotide exchange factor 4 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 6 Rho guanine nucleotide exchange factor 7 Rho guanine nucleotide exchange factor 9 Rho guanine nucleotide exchange factor TIAM1 Rho guanine nucleotide exchange factor TIAM2 Son of sevenless homolog 1 Son of sevenless homolog 2 Triple functional domain protein Tumor necrosis factor receptor superfamily member 16	A1IGU5 A5YM69 A8MVX0 O14827 O15013 O15068 O15085 O43307 O43521 O60229 O75962 O94827 O94989 P01138 P08138 P10911 P15498 P45983 P52735 P63000 P98174 Q07889 Q07890 Q12774 Q12802 Q12979 Q13009 Q14155 Q14344 Q15052 Q15811 Q5JSP0 Q5VST9 Q5VV41 Q6ZSZ5 Q7Z628 Q7Z6J4 Q8IVF5 Q8IW93 Q8N4T4 Q8N5V2 Q8TCU6 Q8TER5 Q92888 Q92934 Q92974 Q96DR7 Q96M96 Q96PE2 Q9H7P9 Q9H8V3 Q9HCE6 Q9NR80 Q9NR81 Q9NXL2 Q9NY61 Q9NZN5 Q9UKW4 Q9Y5V3	AATF ABR AKAP13 ARHDH9 ARHGEF1 ARHGEF10 ARHGEF10L ARHGEF11 ARHGEF12 ARHGEF15 ARHGEF16 ARHGEF17 ARHGEF18 ARHGEF19 ARHGEF2 ARHGEF26 ARHGEF3 ARHGEF33 ARHGEF35 ARHGEF37 ARHGEF38 ARHGEF39 ARHGEF4 ARHGEF40 ARHGEF5 ARHGEF5L ARHGEF6 ARHGEF7 ARHGEF8 ARHGEF9 BAD BBC6 BCL2L11 BCL2L8 BIM BRX C9orf100 CHE1 COOL1 COOL2 DBL DED DUET DUO ECT2 EPHEXIN4 FGD1 FGD2 FGD3 FGD4 FGDY FRABP GNA13 GRF2 GRINCHGEF HAPIP HT31 ITSN ITSN1 JNK1 KALRN KIAA0006 KIAA0142 KIAA0294 KIAA0337 KIAA0362 KIAA0380 KIAA0382 KIAA0424 KIAA0521 KIAA0651 KIAA0720 KIAA0915 KIAA1112 KIAA1415 KIAA1556 KIAA1626 KIAA1639 KIAA2016 LARG LBC LFP40 MAGED1 MAPK8 MCF2 MCF2L NBR NET1 NGEF NGF NGFB NGFR NRAGE OBSCN OST P85SPR PAK3BP PIXA PIXB PLEKHG2 PLEKHG5 PREX1 PRKM8 RAC1 RASGRF2 SAPK1 SAPK1C SGEF SH3D1A SOLO SOS1 SOS2 STEF TC25 TEM4 TIAM1 TIAM2 TIM TNFRSF16 TRAD TRIO VAV VAV1 VAV2 VAV3 ZFYVE3 ZFYVE4 ZFYVE5 ZFYVE6
Degradation of GABA	4-aminobutyrate aminotransferase, mitochondrial Succinate-semialdehyde dehydrogenase, mitochondrial	P51649 P80404	ABAT ALDH5A1 GABAT SSADH
LXRs regulate gene expression linked to cholesterol transport and efflux	ADP-ribosylation factor-like protein 4C ATP-binding cassette sub-family G member 1 ATP-binding cassette sub-family G member 5 ATP-binding cassette sub-family G member 8 Apolipoprotein C-I Apolipoprotein C-II Apolipoprotein C-IV Apolipoprotein D Apolipoprotein E Cholesteryl ester transfer protein Endonuclease/exonuclease/phosphatase family domain-containing protein 1 F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 G protein pathway suppressor 2 Helicase MOV-10 Histone acetyltransferase p300 Histone deacetylase 3 Lysine-specific demethylase 3A Lysine-specific demethylase 4A Lysine-specific histone demethylase 1A Lysine-specific histone demethylase 2 Nuclear receptor coactivator 1 Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 Oxysterols receptor LXR-alpha Oxysterols receptor LXR-beta Phospholipid-transporting ATPase ABCA1 Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Retinoic acid receptor RXR-alpha Retinoic acid receptor RXR-beta Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein	O15379 O60341 O60907 O75164 O75376 O95477 P02649 P02654 P02655 P05090 P11597 P19793 P28702 P45844 P55055 P55056 P56559 Q09472 Q13133 Q13227 Q15788 Q7L9B9 Q8NB78 Q8NDV7 Q9BZK7 Q9H221 Q9H222 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9UKV8 Q9UL18 Q9UPQ9 Q9Y4C1 Q9Y618	ABC1 ABC8 ABCA1 ABCG1 ABCG5 ABCG8 AGO1 AGO2 AGO3 AGO4 AOF1 AOF2 APC2 APOC1 APOC2 APOC4 APOD APOE ARL4C ARL7 BHLHE74 C6orf193 CAGH26 CERP CETP CTG26 EEPD1 EIF2C1 EIF2C2 EIF2C3 EIF2C4 EP300 GPS2 HDAC3 IRA1 JHDM2A JHDM3A JMJD1 JMJD1A JMJD2 JMJD2A KDM1 KDM1A KDM1B KDM3A KDM4A KIAA0601 KIAA0677 KIAA0742 KIAA1047 KIAA1093 KIAA1460 KIAA1567 KIAA1582 KIAA1631 KIAA1706 LSD1 LSD2 LXRA LXRB MOV10 NCOA1 NCOR1 NCOR2 NER NR1H2 NR1H3 NR2B1 NR2B2 P300 RXRA RXRB SRC1 TBL1 TBL1X TBL1XR1 TBLR1 TNRC6 TNRC6A TNRC6B TNRC6C TSGA UNR WHT1
PPARA activates gene expression	3'-5' exoribonuclease HELZ2 5-aminolevulinate synthase, non-specific, mitochondrial Acyl-CoA (8-3)-desaturase Angiopoietin-related protein 4 Angiotensinogen Ankyrin repeat domain-containing protein 1 Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-V Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Aryl hydrocarbon receptor repressor Aryl hydrocarbon receptor Basic helix-loop-helix ARNT-like protein 1 Bile acid receptor CREB-binding protein Carnitine O-palmitoyltransferase 1, liver isoform Carnitine O-palmitoyltransferase 2, mitochondrial Chromodomain-helicase-DNA-binding protein 9 Circadian locomoter output cycles protein kaput Constitutive coactivator of peroxisome proliferator-activated receptor gamma Cyclin-C Cyclin-dependent kinase 19 Cyclin-dependent kinase 8 Cytochrome P450 1A1 Cytochrome P450 4A11 Cytochrome P450 7A1 F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Fatty acid-binding protein, liver Four and a half LIM domains protein 2 G protein pathway suppressor 2 G0/G1 switch protein 2 Glioma pathogenesis-related protein 1 Grainyhead-like protein 1 homolog Histone acetyltransferase p300 Histone deacetylase 3 Histone-arginine methyltransferase CARM1 Hydroxymethylglutaryl-CoA synthase, cytoplasmic Hydroxymethylglutaryl-CoA synthase, mitochondrial Long-chain fatty acid transport protein 1 Long-chain-fatty-acid--CoA ligase 1 Mediator of RNA polymerase II transcription subunit 10 Mediator of RNA polymerase II transcription subunit 11 Mediator of RNA polymerase II transcription subunit 12 Mediator of RNA polymerase II transcription subunit 13-like Mediator of RNA polymerase II transcription subunit 13 Mediator of RNA polymerase II transcription subunit 14 Mediator of RNA polymerase II transcription subunit 15 Mediator of RNA polymerase II transcription subunit 16 Mediator of RNA polymerase II transcription subunit 17 Mediator of RNA polymerase II transcription subunit 18 Mediator of RNA polymerase II transcription subunit 19 Mediator of RNA polymerase II transcription subunit 1 Mediator of RNA polymerase II transcription subunit 20 Mediator of RNA polymerase II transcription subunit 21 Mediator of RNA polymerase II transcription subunit 22 Mediator of RNA polymerase II transcription subunit 23 Mediator of RNA polymerase II transcription subunit 24 Mediator of RNA polymerase II transcription subunit 25 Mediator of RNA polymerase II transcription subunit 26 Mediator of RNA polymerase II transcription subunit 27 Mediator of RNA polymerase II transcription subunit 28 Mediator of RNA polymerase II transcription subunit 29 Mediator of RNA polymerase II transcription subunit 30 Mediator of RNA polymerase II transcription subunit 31 Mediator of RNA polymerase II transcription subunit 4 Mediator of RNA polymerase II transcription subunit 6 Mediator of RNA polymerase II transcription subunit 7 Mediator of RNA polymerase II transcription subunit 8 Mediator of RNA polymerase II transcription subunit 9 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial Metal regulatory transcription factor 1 NADP-dependent malic enzyme Neuronal PAS domain-containing protein 2 Nuclear receptor ROR-alpha Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Nuclear receptor coactivator 3 Nuclear receptor coactivator 6 Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 Nuclear receptor subfamily 1 group D member 1 Nuclear respiratory factor 1 Nuclear transcription factor Y subunit alpha Nuclear transcription factor Y subunit beta Nuclear transcription factor Y subunit gamma Oxysterols receptor LXR-alpha Oxysterols receptor LXR-beta Perilipin-2 Peroxisomal membrane protein 11A Peroxisome proliferator-activated receptor alpha Peroxisome proliferator-activated receptor gamma coactivator 1-alpha Peroxisome proliferator-activated receptor gamma coactivator 1-beta Peroxisome proliferator-activated receptor gamma Phosphatidylcholine translocator ABCB4 Phospholipid-transporting ATPase ABCA1 Platelet glycoprotein 4 Ral guanine nucleotide dissociation stimulator-like 1 Retinoic acid receptor RXR-alpha Retinoic acid receptor RXR-beta Rho guanine nucleotide exchange factor TIAM2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 Squalene synthase Steroid hormone receptor ERR1 Sterol regulatory element-binding protein 2 Sulfotransferase 2A1 Thioredoxin reductase 1, cytoplasmic Thyroid hormone receptor-associated protein 3 Transcription factor Sp1 Tribbles homolog 3 Trimethylguanosine synthase Tumor necrosis factor receptor superfamily member 21 UDP-glucuronosyltransferase 1A9	A0JLT2 A9YTQ3 O00327 O15379 O15516 O43513 O60244 O60427 O60656 O60907 O75192 O75376 O75448 O75509 O75586 O95402 O95477 P01019 P02647 P02652 P04798 P07148 P08047 P11310 P11474 P13196 P16671 P19793 P20393 P21439 P22680 P23511 P23786 P24863 P25208 P27469 P27540 P28702 P33121 P35398 P35869 P37231 P37268 P48060 P48163 P49336 P50416 P54868 P55055 Q01581 Q02928 Q06520 Q07869 Q09472 Q12772 Q13133 Q13227 Q13503 Q13952 Q14192 Q14686 Q14872 Q15327 Q15528 Q15596 Q15648 Q15788 Q16656 Q16881 Q3L8U1 Q6P2C8 Q6PCB7 Q6Q788 Q6STE5 Q71F56 Q71SY5 Q86X55 Q86YN6 Q8IVF5 Q92793 Q93074 Q96EK7 Q96G25 Q96HR3 Q96RI1 Q96RN5 Q96RS0 Q96RU7 Q99541 Q99743 Q9BTT4 Q9BUE0 Q9BWU1 Q9BY76 Q9BYK8 Q9BZK7 Q9H204 Q9H944 Q9HBZ2 Q9NPJ6 Q9NVC6 Q9NWA0 Q9NX70 Q9NZI5 Q9NZL6 Q9P086 Q9UBK2 Q9UHV7 Q9ULK4 Q9Y2W1 Q9Y2X0 Q9Y3C7 Q9Y618 Q9Y6Q9	ABC1 ABCA1 ABCB4 ACADM ACID1 ACSL1 ACSVL5 ADFP AGT AHR AHRR AIB1 AIB3 ALAS1 ALAS3 ALASH ANGPTL4 ANKRD1 APOA1 APOA2 APOA5 ARC100 ARC105 ARC130 ARC150 ARC205 ARC240 ARC250 ARC33 ARC34 ARC36 ARC70 ARC77 ARC92 ARNT ARNT2 ARNTL ARP4 BAF60C BAR BCLAF2 BHLHD2 BHLHE1 BHLHE2 BHLHE42 BHLHE5 BHLHE74 BHLHE75 BHLHE76 BHLHE77 BHLHE8 BHLHE9 BMAL1 C193 C20orf97 CAGH45 CARM1 CARP CBP CCNC CCPG CD36 CDC2L6 CDK11 CDK19 CDK8 CERP CHD9 CLOCK CPT1 CPT1A CPT2 CREBBP CRSP1 CRSP2 CRSP200 CRSP3 CRSP34 CRSP4 CRSP6 CRSP7 CRSP8 CRSP9 CTG26 CTG7A CXorf4 CYP1A1 CYP4A11 CYP4A2 CYP7 CYP7A1 DR6 DRAL DRIP100 DRIP130 DRIP150 DRIP205 DRIP230 DRIP36 DRIP77 DRIP80 DRIP92 EAR1 EG1 EP300 ERR1 ESRL1 ESRRA EXLM1 FABP1 FABPL FACL1 FACL2 FADS1 FADSD5 FAM120B FATP1 FDFT1 FHL2 FXR G0S2 GLIPR GLIPR1 GNT1 GP3B GP4 GPS2 GRHL1 GRIM12 HA1A2 HAP3 HCA137 HDAC3 HELZ2 HFARP HMGCS HMGCS1 HMGCS2 HOPA HREV HRR1 HST IRA1 IXL KDRF KIAA0130 KIAA0181 KIAA0192 KIAA0307 KIAA0308 KIAA0334 KIAA0593 KIAA0959 KIAA1025 KIAA1028 KIAA1047 KIAA1216 KIAA1234 KIAA1769 KIAA1838 KIAA2016 KISH2 LACS LACS1 LACS2 LBP32 LCMR1 LEM6 LXRA LXRB MDR3 ME1 MED1 MED10 MED11 MED12 MED13 MED13L MED14 MED15 MED16 MED17 MED18 MED19 MED20 MED21 MED22 MED23 MED24 MED25 MED26 MED27 MED28 MED29 MED30 MED31 MED4 MED6 MED7 MED8 MED9 MGR MOP3 MOP4 MTF1 NCOA1 NCOA2 NCOA3 NCOA6 NCOA6IP NCOR1 NCOR2 NER NFYA NFYB NFYC NIPK NPAS2 NR1C1 NR1C3 NR1D1 NR1F1 NR1H2 NR1H3 NR1H4 NR2B1 NR2B2 NR3B1 NRF1 P300 PASD3 PASD4 PBP PCQAP PERC PEX11 PEX11A PGAR PGC1 PGC1A PGC1B PGY3 PIMT PLIN2 PPAR PPARA PPARBP PPARG PPARGBP PPARGC1 PPARGC1A PPARGC1B PRIC285 PRIC320 PRMT4 PROSIT240 PTOV2 RAC3 RAP250 RAP3 RB18A RGL RGL1 RGR1 RIP14 RORA RTVP1 RXRA RXRB RZRA SERPINA8 SKIP3 SLC27A1 SLIM3 SMARCD3 SOH1 SP1 SRB7 SRC1 SRC2 SREBF2 SREBP2 STD STEF SULT2A1 SUR2 SURB7 SURF5 TBL1 TBL1X TBL1XR1 TBLR1 TFCP2L2 TGS1 THRAL THRAP1 THRAP2 THRAP3 THRAP4 THRAP5 THRAP6 TIAM2 TIF2 TIG1 TNFRSF21 TNRC11 TNRC7 TRAM1 TRAP100 TRAP150 TRAP170 TRAP220 TRAP230 TRAP240 TRAP240L TRAP25 TRAP80 TRB3 TRBP TRFP TRIB3 TRIP2 TSFP1 TXNRD1 UGT1 UGT1A9 UNR VDRIP
Defective ABCA1 causes TGD	Apolipoprotein A-I Phospholipid-transporting ATPase ABCA1	O95477 P02647	ABC1 ABCA1 APOA1 CERP
ABC transporters in lipid homeostasis	ATP-binding cassette sub-family A member 10 ATP-binding cassette sub-family A member 2 ATP-binding cassette sub-family A member 6 ATP-binding cassette sub-family A member 9 ATP-binding cassette sub-family D member 1 ATP-binding cassette sub-family D member 2 ATP-binding cassette sub-family D member 3 ATP-binding cassette sub-family G member 1 ATP-binding cassette sub-family G member 4 ATP-binding cassette sub-family G member 5 ATP-binding cassette sub-family G member 8 Apolipoprotein A-I Cholesterol transporter ABCA5 Glucosylceramide transporter ABCA12 Peroxisomal biogenesis factor 19 Peroxisomal biogenesis factor 3 Phospholipid-transporting ATPase ABCA3 Phospholipid-transporting ATPase ABCA7	P02647 P28288 P33897 P40855 P45844 P56589 Q86UK0 Q8IUA7 Q8IZY2 Q8N139 Q8WWZ4 Q8WWZ7 Q99758 Q9BZC7 Q9H172 Q9H221 Q9H222 Q9UBJ2	ABC12 ABC2 ABC3 ABC8 ABCA10 ABCA12 ABCA2 ABCA3 ABCA5 ABCA6 ABCA7 ABCA9 ABCD1 ABCD2 ABCD3 ABCG1 ABCG4 ABCG5 ABCG8 ALD ALD1 ALDL1 ALDR ALDRP APOA1 HK33 KIAA1062 KIAA1888 PEX19 PEX3 PMP70 PXF PXMP1 WHITE2 WHT1
Defective ABCA12 causes ARCI4B	Glucosylceramide transporter ABCA12	Q86UK0	ABC12 ABCA12
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Eukaryotic initiation factor 4A-III Eukaryotic peptide chain release factor GTP-binding subunit ERF3A Eukaryotic peptide chain release factor GTP-binding subunit ERF3B Eukaryotic peptide chain release factor subunit 1 Eukaryotic translation initiation factor 4 gamma 1 Large ribosomal subunit protein P1 Large ribosomal subunit protein P2 Large ribosomal subunit protein eL13 Large ribosomal subunit protein eL14 Large ribosomal subunit protein eL15 Large ribosomal subunit protein eL18 Large ribosomal subunit protein eL19 Large ribosomal subunit protein eL20 Large ribosomal subunit protein eL21 Large ribosomal subunit protein eL22 Large ribosomal subunit protein eL24 Large ribosomal subunit protein eL27 Large ribosomal subunit protein eL28 Large ribosomal subunit protein eL29 Large ribosomal subunit protein eL30 Large ribosomal subunit protein eL31 Large ribosomal subunit protein eL32 Large ribosomal subunit protein eL33 Large ribosomal subunit protein eL34 Large ribosomal subunit protein eL36 Large ribosomal subunit protein eL37 Large ribosomal subunit protein eL38 Large ribosomal subunit protein eL39 Large ribosomal subunit protein eL42 Large ribosomal subunit protein eL43 Large ribosomal subunit protein eL6 Large ribosomal subunit protein eL8 Large ribosomal subunit protein uL10 Large ribosomal subunit protein uL11 Large ribosomal subunit protein uL13 Large ribosomal subunit protein uL14 Large ribosomal subunit protein uL15 Large ribosomal subunit protein uL16 Large ribosomal subunit protein uL18 Large ribosomal subunit protein uL1 Large ribosomal subunit protein uL22 Large ribosomal subunit protein uL23 Large ribosomal subunit protein uL24 Large ribosomal subunit protein uL29 Large ribosomal subunit protein uL2 Large ribosomal subunit protein uL30 Large ribosomal subunit protein uL3 Large ribosomal subunit protein uL4 Large ribosomal subunit protein uL5 Large ribosomal subunit protein uL6 Nonsense-mediated mRNA decay factor SMG5 Nonsense-mediated mRNA decay factor SMG7 Nonsense-mediated mRNA decay factor SMG8 Nonsense-mediated mRNA decay factor SMG9 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Polyadenylate-binding protein 1 Proline-rich nuclear receptor coactivator 2 Protein CASC3 Protein mago nashi homolog 2 Protein mago nashi homolog RNA-binding protein 8A RNA-binding protein with serine-rich domain 1 Regulator of nonsense transcripts 1 Regulator of nonsense transcripts 2 Regulator of nonsense transcripts 3A Regulator of nonsense transcripts 3B Ribosomal protein eL22-like Ribosomal protein eL39-like 2 Ribosomal protein eL42-like Ribosomal protein eS27-like Ribosomal protein uL16-like Ribosomal protein uL24-like Ribosomal protein uL3-like Serine/threonine-protein kinase SMG1 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Small ribosomal subunit protein eS10 Small ribosomal subunit protein eS12 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS32 Small ribosomal subunit protein eS4, X isoform Small ribosomal subunit protein eS4, Y isoform 1 Small ribosomal subunit protein eS4, Y isoform 2 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS8 Small ribosomal subunit protein uS9 Telomerase-binding protein EST1A Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein mRNA-decapping enzyme 1A	O15234 P05386 P05387 P05388 P08708 P08865 P11940 P15170 P15880 P18077 P18124 P18621 P22090 P23396 P25398 P26373 P27635 P30050 P30153 P32969 P35268 P36578 P38919 P39019 P39023 P40429 P42677 P42766 P46776 P46777 P46778 P46779 P46781 P46782 P46783 P47914 P49207 P50914 P52298 P60866 P61247 P61254 P61313 P61326 P61353 P61513 P61927 P62081 P62241 P62244 P62249 P62263 P62266 P62269 P62273 P62277 P62280 P62424 P62495 P62701 P62750 P62753 P62829 P62841 P62847 P62851 P62854 P62857 P62861 P62888 P62891 P62899 P62906 P62910 P62913 P62917 P62945 P62979 P62987 P63151 P63173 P63220 P67775 P83731 P83881 P84098 Q02543 Q02878 Q04637 Q07020 Q09161 Q15287 Q6P5R6 Q71UM5 Q86US8 Q8IYD1 Q8ND04 Q8TD47 Q92540 Q92900 Q92901 Q969Q0 Q96A72 Q96EH5 Q96L21 Q96Q15 Q9BZI7 Q9H0W8 Q9H1J1 Q9HAU5 Q9NPI6 Q9NPJ4 Q9UNX3 Q9UPR3 Q9Y3U8 Q9Y5S9	ABC2 ATX BBC1 C17orf31 C17orf71 C19orf61 C1orf16 CASC3 CBP20 CBP80 CCG2 D11S2243E D6S218E DCP1A DDX48 DXS648E EC45 EIF4A3 EIF4F EIF4G EIF4G1 EIF4GI ERF1 ERF3A ERF3B EST1A EST1B EST1C ETF1 FAU FTE1 GSPT1 GSPT2 KIAA0111 KIAA0221 KIAA0250 KIAA0421 KIAA0732 KIAA1089 KIAA1408 LAMBR LAMR1 LDC2 LIP MAGOH MAGOH2 MAGOHA MAGOHB MFTL MLN51 MPS1 NCBP NCBP1 NCBP2 NEDD6 PAB1 PABP PABP1 PABPC1 PABPC2 PNRC2 PPP2CA PPP2R1A PPP2R2A QM RBM8 RBM8A RENT1 RENT2 RENT3A RENT3B RF1 RIG RNPS1 RPL1 RPL10 RPL10A RPL10L RPL11 RPL12 RPL13 RPL13A RPL14 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL22L1 RPL23 RPL23A RPL24 RPL26 RPL26L1 RPL26P1 RPL27 RPL27A RPL28 RPL29 RPL3 RPL30 RPL31 RPL32 RPL34 RPL35 RPL35A RPL36 RPL36A RPL36AL RPL37 RPL37A RPL38 RPL39 RPL39L RPL39L1 RPL3L RPL4 RPL41 RPL44 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPL9P7 RPL9P8 RPL9P9 RPLP0 RPLP1 RPLP2 RPP2 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS17L RPS18 RPS19 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS27L RPS28 RPS29 RPS3 RPS3A RPS4 RPS4X RPS4Y RPS4Y1 RPS4Y2 RPS4Y2P RPS5 RPS6 RPS7 RPS8 RPS9 RPSA RRP1 SCAR SMG1 SMG5 SMG6 SMG7 SMG8 SMG9 SMIF SUP45L1 SURF-3 SURF3 TXREB1 UBA52 UBA80 UBCEP1 UBCEP2 UPF1 UPF2 UPF3 UPF3A UPF3B UPF3X
Surfactant metabolism	Adenosine deaminase 2 Adenosine receptor A2a Adenosine receptor A2b Adhesion G protein-coupled receptor F5 Alpha-2A adrenergic receptor Alpha-2C adrenergic receptor Cytokine receptor common subunit beta Cytoskeleton-associated protein 4 Deleted in malignant brain tumors 1 protein Granulocyte-macrophage colony-stimulating factor receptor subunit alpha LIM and cysteine-rich domains protein 1 Napsin-A P2Y purinoceptor 2 Palmitoyltransferase ZDHHC2 Pepsin A-3 Pepsin A-4 Pepsin A-5 Phospholipid-transporting ATPase ABCA3 Pro-cathepsin H Pulmonary surfactant-associated protein A1 Pulmonary surfactant-associated protein A2 Pulmonary surfactant-associated protein B Pulmonary surfactant-associated protein D Sodium-dependent phosphate transport protein 2A Sodium-dependent phosphate transport protein 2B Surfactant protein C Surfactant-associated protein 3 Thyroid transcription factor 1-associated protein 26 Transcription factor GATA-6 Transcription termination factor 1	O95436 O96009 P07988 P08913 P09668 P0C7M3 P0DJD7 P0DJD8 P0DJD9 P11686 P15509 P18825 P29274 P29275 P32927 P35247 P41231 Q06495 Q07065 Q15361 Q8IWL1 Q8IWL2 Q8IZF2 Q92908 Q99758 Q9NZK5 Q9NZU5 Q9P031 Q9UGM3 Q9UIJ5	ABC3 ABCA3 ADA2 ADGF ADGRF5 ADORA2 ADORA2A ADORA2B ADRA2A ADRA2C ADRA2L2 ADRA2R ADRA2RL2 ADRAR BR22 CCDC59 CECR1 CKAP4 COLEC4 COLEC5 COLEC7 CPSB CSF2R CSF2RA CSF2RB CSF2RY CTSH DMBT1 GATA6 GP340 GPR116 IDGFL IL3RB IL5RB KIAA0758 LMCD1 NAP1 NAPA NAPSA NPT2 P2RU1 P2RY2 PGA3 PGA4 PGA5 PSAP PSPD REAM REC SFTA3 SFTP1 SFTP2 SFTP3 SFTP4 SFTPA SFTPA1 SFTPA1B SFTPA2 SFTPA2B SFTPB SFTPC SFTPD SFTPH SLC17A2 SLC34A1 SLC34A2 TAP26 TTF1 ZDHHC2 ZNF372
Defective ABCA3 causes SMDP3	Phospholipid-transporting ATPase ABCA3	Q99758	ABC3 ABCA3
Defective ABCA3 causes SMDP3	Phospholipid-transporting ATPase ABCA3	Q99758	ABC3 ABCA3
ABC-family proteins mediated transport	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 ABC-type oligopeptide transporter ABCB9 ABC-type organic anion transporter ABCA8 ATP-binding cassette sub-family B member 5 ATP-binding cassette sub-family C member 10 ATP-binding cassette sub-family C member 11 ATP-binding cassette sub-family C member 2 ATP-binding cassette sub-family C member 3 ATP-binding cassette sub-family C member 4 ATP-binding cassette sub-family C member 5 ATP-binding cassette sub-family C member 6 ATP-binding cassette sub-family C member 9 ATP-binding cassette sub-family F member 1 ATP-dependent translocase ABCB1 ATP-sensitive inward rectifier potassium channel 11 Cystic fibrosis transmembrane conductance regulator Derlin-1 Derlin-2 Derlin-3 E3 ubiquitin-protein ligase RNF185 E3 ubiquitin-protein ligase RNF5 Endoplasmic reticulum lectin 1 Erlin-1 Erlin-2 Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Multidrug resistance-associated protein 1 Phosphatidylcholine translocator ABCB4 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein OS-9 Protein sel-1 homolog 1 Retinal-specific phospholipid-transporting ATPase ABCA4 Transitional endoplasmic reticulum ATPase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O15438 O15439 O15440 O43242 O60706 O75477 O75832 O94905 O94911 O95255 P05198 P08183 P0CG47 P0CG48 P13569 P17980 P20042 P20618 P21439 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P33527 P35998 P40306 P41091 P43686 P48556 P49720 P49721 P51665 P55036 P55072 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 P78363 Q06323 Q13200 Q13438 Q14654 Q14997 Q15008 Q16401 Q2M3G0 Q5T3U5 Q8NE71 Q8TAA3 Q92530 Q92887 Q96DZ1 Q96GF1 Q96J66 Q96Q80 Q99436 Q99460 Q99942 Q9BUN8 Q9GZP9 Q9NP78 Q9UBV2 Q9UL46 Q9UNM6	ABC50 ABCA4 ABCA8 ABCB1 ABCB4 ABCB5 ABCB9 ABCC1 ABCC10 ABCC11 ABCC2 ABCC3 ABCC4 ABCC5 ABCC6 ABCC7 ABCC9 ABCF1 ABCR ARA C10orf69 C22orf14 C2orf30 C7orf76 C8orf2 CFTR CMOAT CMOAT1 CMOAT2 CMRP DER1 DER2 DER3 DERL1 DERL2 DERL3 DSS1 EIF2A EIF2B EIF2G EIF2S1 EIF2S2 EIF2S3 ERLEC1 ERLIN1 ERLIN2 FLANA G16 HC2 HC3 HC8 HC9 HEL-220 HEL-S-70 HSPC IFI5111 KCNJ11 KE04 KEO4 KIAA0072 KIAA0077 KIAA0107 KIAA0822 KIAA1520 LLN2 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MDR1 MDR3 MECL1 MIP224 MLP2 MOATB MOV34L MRP MRP1 MRP2 MRP3 MRP4 MRP5 MRP6 MRP7 MRP8 MSS1 NG2 NU OS9 PFAAP4 PGY1 PGY3 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RING10 RING12 RMA1 RNF185 RNF5 RPS27A SEL1L SEM1 SHFDG1 SHFM1 SIMRP7 SPFH1 SPFH2 SUG1 SUG2 SUR2 TBP1 TBP7 TRAP2 TSA305 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VCP X XTP3TPB Y Y2 Z
Mitochondrial ABC transporters	ATP-binding cassette sub-family B member 10, mitochondrial ATP-binding cassette sub-family B member 6 Iron-sulfur clusters transporter ABCB7, mitochondrial Mitochondrial potassium channel ATP-binding subunit	O75027 Q9NP58 Q9NRK6 Q9NUT2	ABC7 ABCB10 ABCB6 ABCB7 ABCB8 MABC1 MITOSUR MTABC3 PRP UMAT
Cytosolic iron-sulfur cluster assembly	Anamorsin Cytosolic Fe-S cluster assembly factor NUBP1 Cytosolic Fe-S cluster assembly factor NUBP2 Cytosolic iron-sulfur assembly component 2B Cytosolic iron-sulfur assembly component 3 DNA polymerase delta catalytic subunit Fanconi anemia group J protein General transcription and DNA repair factor IIH helicase subunit XPD Iron-sulfur clusters transporter ABCB7, mitochondrial MMS19 nucleotide excision repair protein homolog NADPH-dependent diflavin oxidoreductase 1 Probable cytosolic iron-sulfur protein assembly protein CIAO1 Regulator of telomere elongation helicase 1	O75027 O76071 P18074 P28340 P53384 Q6FI81 Q96T76 Q9BX63 Q9H6Q4 Q9NZ71 Q9UHB4 Q9Y3D0 Q9Y5Y2	ABC7 ABCB7 BACH1 BRIP1 C20orf41 CIA1 CIAB CIAO1 CIAO2B CIAO3 CIAPIN1 ERCC2 FAM96B FANCJ KIAA1088 MIP18 MMS19 MMS19L NARFL NBP NBP1 NDOR1 NHL NR1 NUBP1 NUBP2 POLD POLD1 PRN RTEL1 WDR39 XPD XPDC
HDL remodeling	ATP-binding cassette sub-family G member 1 Albumin Apolipoprotein A-I Apolipoprotein C-II Apolipoprotein C-III Apolipoprotein E Cholesteryl ester transfer protein Endothelial lipase Phosphatidylcholine-sterol acyltransferase	P02647 P02649 P02655 P02656 P02768 P04180 P11597 P45844 Q9Y5X9	ABC8 ABCG1 ALB APC2 APOA1 APOC2 APOC3 APOE CETP LCAT LIPG WHT1
The canonical retinoid cycle in rods (twilight vision)	17-beta-hydroxysteroid dehydrogenase type 1 17-beta-hydroxysteroid dehydrogenase type 6 Cytochrome P450 4V2 Dehydrogenase/reductase SDR family member 9 Lecithin retinol acyltransferase Receptor for retinol uptake STRA6 Retinal-specific phospholipid-transporting ATPase ABCA4 Retinaldehyde-binding protein 1 Retinoid isomerohydrolase Retinol dehydrogenase 10 Retinol dehydrogenase 11 Retinol dehydrogenase 12 Retinol dehydrogenase 16 Retinol dehydrogenase 5 Retinol dehydrogenase 8 Retinol-binding protein 1 Retinol-binding protein 3 Retinol-binding protein 4 Rhodopsin Short-chain dehydrogenase/reductase family 9C member 7 Transthyretin Unconventional myosin-VIIa	O14756 O75452 O95237 P02753 P02766 P08100 P09455 P10745 P12271 P14061 P78363 Q13402 Q16518 Q6ZWL3 Q8IZV5 Q8NEX9 Q8TC12 Q92781 Q96NR8 Q9BPW9 Q9BX79 Q9NYR8	ABCA4 ABCR ARSDR1 CRALBP CRBP1 CYP4V2 DHRS9 E17KSR EDH17B1 EDH17B2 EDHB17 HSD17B1 HSD17B6 HSD17B9 LRAT MYO7A OPN2 PALB PRRDH PSDR1 RBP1 RBP3 RBP4 RDH1 RDH10 RDH11 RDH12 RDH15 RDH16 RDH5 RDH8 RDHS RHO RLBP1 RODH RODH4 RPE65 SDR16C4 SDR28C1 SDR28C2 SDR7C1 SDR7C2 SDR9C4 SDR9C5 SDR9C6 SDR9C7 SDR9C8 SDRO STRA6 TTR USH1B
Retinoid cycle disease events	Lecithin retinol acyltransferase Long-wave-sensitive opsin 1 Medium-wave-sensitive opsin 1 Receptor for retinol uptake STRA6 Retinal-specific phospholipid-transporting ATPase ABCA4 Retinaldehyde-binding protein 1 Retinol dehydrogenase 12 Retinol dehydrogenase 5 Retinol-binding protein 1 Retinol-binding protein 4 Short-wave-sensitive opsin 1 Transthyretin	O95237 P02753 P02766 P03999 P04000 P04001 P09455 P12271 P78363 Q92781 Q96NR8 Q9BX79	ABCA4 ABCR BCP CRALBP CRBP1 GCP HSD17B9 LRAT OPN1LW OPN1MW OPN1SW PALB RBP1 RBP4 RCP RDH1 RDH12 RDH5 RLBP1 SDR7C2 SDR9C5 STRA6 TTR
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	ATP-binding cassette sub-family A member 6 Agouti-related protein Ataxin-3 Catalase E3 ubiquitin-protein ligase TRIM63 F-box only protein 32 Forkhead box protein O1 Forkhead box protein O3 Forkhead box protein O4 Forkhead box protein O6 Glucocorticoid receptor Glucose-6-phosphatase catalytic subunit 1 Hexokinase-4 Histone deacetylase 1 Histone deacetylase 2 Insulin-like growth factor-binding protein 1 Insulin Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 NAD-dependent protein deacetylase sirtuin-3, mitochondrial Paired amphipathic helix protein Sin3a Peroxisome proliferator-activated receptor gamma coactivator 1-alpha Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Plexin-A4 Pro-neuropeptide Y Pro-opiomelanocortin Resistin Sterol regulatory element-binding protein 1 Superoxide dismutase [Mn], mitochondrial	A8MYZ6 O00253 O43524 P01189 P01303 P01308 P04040 P04150 P04179 P08833 P35557 P35558 P35575 P36956 P54252 P84022 P98177 Q12778 Q13485 Q13547 Q15796 Q8N139 Q92769 Q969P5 Q969Q1 Q96ST3 Q9HCM2 Q9HD89 Q9NTG7 Q9UBK2	ABCA6 AFX AFX1 AGRP AGRT ART ATX3 ATXN3 BHLHD1 CAT DPC4 FBXO32 FIZZ3 FKHR FKHRL1 FOXO1 FOXO1A FOXO3 FOXO3A FOXO4 FOXO6 G6PC G6PC1 G6PT GCK GRL HDAC1 HDAC2 HXCP1 IBP1 IGFBP1 INS IRF KIAA1550 LEM6 MADH2 MADH3 MADH4 MADR2 MJD MJD1 MLLT7 MURF1 NPY NR3C1 PCK1 PEPCK1 PGC1 PGC1A PLXNA4 PLXNA4A PLXNA4B POMC PPARGC1 PPARGC1A RETN RNF28 RPD3L1 RSTN SCA3 SIN3A SIR2L3 SIRT3 SMAD2 SMAD3 SMAD4 SMRZ SOD2 SREBF1 SREBP1 TRIM63
Atorvastatin ADME	ATP-binding cassette sub-family C member 2 ATP-dependent translocase ABCB1 Cytochrome P450 3A4 Serum paraoxonase/arylesterase 1 Serum paraoxonase/lactonase 3 Solute carrier organic anion transporter family member 1B1 Solute carrier organic anion transporter family member 1B3 UDP-glucuronosyltransferase 1A3	P08183 P08684 P27169 P35503 Q15166 Q92887 Q9NPD5 Q9Y6L6	ABCB1 ABCC2 CMOAT CMOAT1 CMRP CYP3A3 CYP3A4 GNT1 LST1 LST2 MDR1 MRP2 OATP1B1 OATP1B3 OATP2 OATP8 OATPC PGY1 PON PON1 PON3 SLC21A6 SLC21A8 SLCO1B1 SLCO1B3 UGT1 UGT1A3
Abacavir transmembrane transport	ATP-dependent translocase ABCB1 Broad substrate specificity ATP-binding cassette transporter ABCG2 Solute carrier family 22 member 1 Solute carrier family 22 member 2 Solute carrier family 22 member 3	O15244 O15245 O75751 P08183 Q9UNQ0	ABCB1 ABCG2 ABCP BCRP BCRP1 EMTH MDR1 MXR OCT1 OCT2 OCT3 PGY1 SLC22A1 SLC22A2 SLC22A3
Prednisone ADME	11-beta-hydroxysteroid dehydrogenase 1 11-beta-hydroxysteroid dehydrogenase type 2 ATP-dependent translocase ABCB1 Albumin Aldo-keto reductase family 1 member C1 Corticosteroid-binding globulin Cytochrome P450 3A4 UDP-glucuronosyltransferase 1A3 UDP-glucuronosyltransferase 2B17 UDP-glucuronosyltransferase 2B7	O75795 P02768 P08183 P08185 P08684 P16662 P28845 P35503 P80365 Q04828	ABCB1 AKR1C1 ALB CBG CYP3A3 CYP3A4 DDH DDH1 GNT1 HSD11 HSD11B1 HSD11B2 HSD11K HSD11L MDR1 PGY1 SDR26C1 SDR9C3 SERPINA6 UGT1 UGT1A3 UGT2B17 UGT2B7 UGTB2B9
Recycling of bile acids and salts	ATP-binding cassette sub-family C member 3 Albumin Bile acid receptor Bile acid-CoA Bile salt export pump Gastrotropin Hepatic sodium/bile acid cotransporter Ileal sodium/bile acid cotransporter Long-chain fatty acid transport protein 5 Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Organic solute transporter subunit alpha Organic solute transporter subunit beta Retinoic acid receptor RXR-alpha Solute carrier organic anion transporter family member 1A2 Solute carrier organic anion transporter family member 1B1 Solute carrier organic anion transporter family member 1B3 StAR-related lipid transfer protein 5	O15438 O95342 P02768 P19793 P46721 P51161 Q12908 Q14032 Q14973 Q15596 Q15788 Q86UW1 Q86UW2 Q96RI1 Q9NPD5 Q9NSY2 Q9Y2P5 Q9Y6L6	ABCB11 ABCC3 ACSB ACSVL6 ALB ASBT BAAT BAR BHLHE74 BHLHE75 BSEP CMOAT2 FABP6 FACVL3 FATP5 FXR HRR1 ILBP ILLBP ISBT LST1 LST2 MLP2 MRP3 NCOA1 NCOA2 NR1H4 NR2B1 NTCP NTCP2 OATP OATP1 OATP1A2 OATP1B1 OATP1B3 OATP2 OATP8 OATPC OSTA OSTB RIP14 RXRA SLC10A1 SLC10A2 SLC21A3 SLC21A6 SLC21A8 SLC27A5 SLC51A SLC51B SLCO1A2 SLCO1B1 SLCO1B3 SRC1 SRC2 STARD5 TIF2
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol	3 beta-hydroxysteroid dehydrogenase type 7 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase Acyl-coenzyme A thioesterase 8 Aldo-keto reductase family 1 member C1 Aldo-keto reductase family 1 member C2 Aldo-keto reductase family 1 member C3 Aldo-keto reductase family 1 member C4 Aldo-keto reductase family 1 member D1 Alpha-methylacyl-CoA racemase Bile acid receptor Bile acid-CoA Bile salt export pump Cytochrome P450 7A1 Cytochrome P450 7B1 Long-chain fatty acid transport protein 2 Long-chain fatty acid transport protein 5 Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Peroxisomal acyl-coenzyme A oxidase 2 Peroxisomal multifunctional enzyme type 2 Prostacyclin synthase Retinoic acid receptor RXR-alpha Sterol 26-hydroxylase, mitochondrial	O14734 O14975 O75881 O95342 P17516 P19793 P22680 P42330 P51659 P51857 P52895 Q02318 Q04828 Q14032 Q15596 Q15788 Q16647 Q96RI1 Q99424 Q9H2F3 Q9UHK6 Q9UNU6 Q9Y2P5	ABCB11 ACOT8 ACOX2 ACSB ACSVL1 ACSVL6 ACTEIII AKR1C1 AKR1C2 AKR1C3 AKR1C4 AKR1D1 AMACR BAAT BAR BHLHE74 BHLHE75 BSEP CHDR CYP12 CYP27 CYP27A1 CYP7 CYP7A1 CYP7B1 CYP8 CYP8A1 CYP8B1 DDH DDH1 DDH2 EDH17B4 FACVL1 FACVL3 FATP2 FATP5 FXR HRR1 HSD17B4 HSD17B5 HSD3B7 KIAA0119 NCOA1 NCOA2 NR1H4 NR2B1 PGFS PTE1 PTGIS RIP14 RXRA SDR8C1 SLC27A2 SLC27A5 SRC1 SRC2 SRD5B1 TIF2 VLACS
Defective ABCB11 causes PFIC2 and BRIC2	Bile salt export pump	O95342	ABCB11 BSEP

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