GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1201 - 1225** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼	Organism	GlyTouCan ID
Regulation of TLR by endogenous ligand	Apolipoprotein B-100 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Gasdermin-D Gasdermin-E High mobility group protein B1 Lipopolysaccharide-binding protein Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Platelet glycoprotein 4 Protein S100-A1 Protein S100-A8 Protein S100-A9 Toll-like receptor 1 Toll-like receptor 2 Toll-like receptor 4 Toll-like receptor 6 Toll-like receptor 7	O00206 O60443 O60603 P02671 P02675 P02679 P04114 P05109 P06702 P08571 P09429 P16671 P18428 P23297 P57764 Q15399 Q9NYK1 Q9Y2C9 Q9Y6Y9	APOB CAGA CAGB CD14 CD36 CFAG DFNA5 DFNA5L ESOP1 FGA FGB FGG GP3B GP4 GSDMD GSDMDC1 GSDME HMG1 HMGB1 ICERE1 KIAA0012 LBP LY96 MD2 MRP14 MRP8 S100A S100A1 S100A8 S100A9 TIL4 TLR1 TLR2 TLR4 TLR6 TLR7	Homo sapiens (human)
LDL remodeling	Apolipoprotein B-100 Apolipoprotein F Apolipoprotein(a) Cholesteryl ester transfer protein Microsomal triglyceride transfer protein large subunit Protein disulfide-isomerase	P04114 P07237 P08519 P11597 P55157 Q13790	APOB APOF CETP ERBA2L LPA MTP MTTP P4HB PDI PDIA1 PO4DB	Homo sapiens (human)
Platelet sensitization by LDL	Apolipoprotein B-100 Cytosolic phospholipase A2 Low-density lipoprotein receptor-related protein 8 Mitogen-activated protein kinase 14 Platelet endothelial cell adhesion molecule Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Tyrosine-protein kinase Fgr Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6	P04114 P09769 P16284 P29350 P30153 P30154 P47712 P62714 P67775 Q06124 Q13362 Q14114 Q14738 Q15172 Q15173 Q16537 Q16539	APOB APOER2 CPLA2 CSBP CSBP1 CSBP2 CSPB1 FGR HCP KIAA0044 LRP8 MAPK14 MXI2 PECAM1 PLA2G4 PLA2G4A PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PTP1C PTP2C PTPN11 PTPN6 SAPK2A SHPTP2 SRC2	Homo sapiens (human)
Chylomicron clearance	Apolipoprotein B-100 Apolipoprotein E Hepatic triacylglycerol lipase Low density lipoprotein receptor adapter protein 1 Low-density lipoprotein receptor	P01130 P02649 P04114 P11150 Q5SW96	APOB APOE ARH HTGL LDLR LDLRAP1 LIPC	Homo sapiens (human)
VLDL assembly	Apolipoprotein B-100 Apolipoprotein C-I Apolipoprotein C-IV Microsomal triglyceride transfer protein large subunit Protein disulfide-isomerase	P02654 P04114 P07237 P55056 P55157	APOB APOC1 APOC4 ERBA2L MTP MTTP P4HB PDI PDIA1 PO4DB	Homo sapiens (human)
VLDL clearance	Apolipoprotein B receptor Apolipoprotein B-100 Apolipoprotein C-I Apolipoprotein C-IV Lipolysis-stimulated lipoprotein receptor Very low-density lipoprotein receptor	P02654 P04114 P55056 P98155 Q0VD83 Q86X29	APOB APOB48R APOBR APOC1 APOC4 ILDR3 LISCH LSR VLDLR	Homo sapiens (human)
Scavenging by Class B Receptors	Apolipoprotein A-I Apolipoprotein B-100 Platelet glycoprotein 4 Serum amyloid A-1 protein Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D	A1L4H1 P02647 P04114 P0DJI8 P16671	APOA1 APOB CD36 GP3B GP4 SAA1 SSC5D	Homo sapiens (human)
Scavenging by Class A Receptors	Apolipoprotein A-I Apolipoprotein B-100 Apolipoprotein E Calreticulin Collagen alpha-1(I) chain Collagen alpha-1(III) chain Collagen alpha-1(IV) chain Collagen alpha-2(I) chain Collagen alpha-2(IV) chain Collectin-11 Collectin-12 Endoplasmin Ferritin heavy chain Ferritin light chain Macrophage receptor MARCO Macrophage scavenger receptor types I and II Mannan-binding lectin serine protease 1 Scavenger receptor class A member 5 Secretoglobin family 3A member 2	P02452 P02461 P02462 P02647 P02649 P02792 P02794 P04114 P08123 P08572 P14625 P21757 P27797 P48740 Q5KU26 Q6ZMJ2 Q96PL1 Q9BWP8 Q9UEW3	APOA1 APOB APOE CALR CLP1 COL1A1 COL1A2 COL3A1 COL4A1 COL4A2 COLEC11 COLEC12 CRARF CRARF1 CRTC FTH FTH1 FTHL6 FTL GRP94 HSP90B1 HSPC4 MARCO MASP1 MSR1 NSR2 PNSP1 PRSS5 SCARA1 SCARA2 SCARA4 SCARA5 SCGB3A2 SRCL TRA1 UGRP1	Homo sapiens (human)	G27025MB G70323CJ G82576YO
TP53 Regulates Transcription of Death Receptors and Ligands	Apoptosis-stimulating of p53 protein 1 Apoptosis-stimulating of p53 protein 2 Cellular tumor antigen p53 Insulin-like growth factor-binding protein 3 receptor Insulin-like growth factor-binding protein 3 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 10C Tumor necrosis factor receptor superfamily member 10D Tumor necrosis factor receptor superfamily member 6 Tumor protein 63 Tumor protein p73	O00220 O14763 O14798 O15350 P04637 P17936 P25445 Q13625 Q86XT9 Q96KQ4 Q9H3D4 Q9UBN6	APO2 APT1 ASPP1 ASPP2 BBP DCR1 DCR2 DR4 DR5 FAS FAS1 IBP3 IGFBP3 KET KIAA0771 KILLER LIT P53 P63 P73 P73H P73L PPP1R13B TMEM219 TNFRSF10A TNFRSF10B TNFRSF10C TNFRSF10D TNFRSF6 TP53 TP53BP2 TP63 TP73 TP73L TRAILR1 TRAILR2 TRAILR3 TRAILR4 TRICK2 TRID TRUNDD ZTNFR9	Homo sapiens (human)
TRAIL signaling	CASP8 and FADD-like apoptosis regulator Caspase-10 Caspase-8 FAS-associated death domain protein Tumor necrosis factor ligand superfamily member 10 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 10D	O00220 O14763 O15519 P50591 Q13158 Q14790 Q92851 Q9UBN6	APO2 APO2L CASH CASP10 CASP8 CASP8AP1 CFLAR CLARP DCR2 DR4 DR5 FADD KILLER MCH4 MCH5 MORT1 MRIT TNFRSF10A TNFRSF10B TNFRSF10D TNFSF10 TRAIL TRAILR1 TRAILR2 TRAILR4 TRICK2 TRUNDD ZTNFR9	Homo sapiens (human)
CASP8 activity is inhibited	Caspase-8 FAS-associated death domain protein Receptor-interacting serine/threonine-protein kinase 1 TNF receptor-associated factor 2 Tumor necrosis factor ligand superfamily member 10 Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor type 1-associated DEATH domain protein	O00220 O14763 P25445 P48023 P50591 Q12933 Q13158 Q13546 Q14790 Q15628	APO2 APO2L APT1 APT1LG1 CASP8 CD95L DR4 DR5 FADD FAS FAS1 FASL FASLG KILLER MCH5 MORT1 RIP RIP1 RIPK1 TNFRSF10A TNFRSF10B TNFRSF6 TNFSF10 TNFSF6 TRADD TRAF2 TRAIL TRAILR1 TRAILR2 TRAP3 TRICK2 ZTNFR9	Homo sapiens (human)
Regulation by c-FLIP	Caspase-8 FAS-associated death domain protein Receptor-interacting serine/threonine-protein kinase 1 TNF receptor-associated factor 2 Tumor necrosis factor ligand superfamily member 10 Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor type 1-associated DEATH domain protein	O00220 O14763 P25445 P48023 P50591 Q12933 Q13158 Q13546 Q14790 Q15628	APO2 APO2L APT1 APT1LG1 CASP8 CD95L DR4 DR5 FADD FAS FAS1 FASL FASLG KILLER MCH5 MORT1 RIP RIP1 RIPK1 TNFRSF10A TNFRSF10B TNFRSF6 TNFSF10 TNFSF6 TRADD TRAF2 TRAIL TRAILR1 TRAILR2 TRAP3 TRICK2 ZTNFR9	Homo sapiens (human)
Dimerization of procaspase-8	Caspase-8 FAS-associated death domain protein Receptor-interacting serine/threonine-protein kinase 1 TNF receptor-associated factor 2 Tumor necrosis factor ligand superfamily member 10 Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor type 1-associated DEATH domain protein	O00220 O14763 P25445 P48023 P50591 Q12933 Q13158 Q13546 Q14790 Q15628	APO2 APO2L APT1 APT1LG1 CASP8 CD95L DR4 DR5 FADD FAS FAS1 FASL FASLG KILLER MCH5 MORT1 RIP RIP1 RIPK1 TNFRSF10A TNFRSF10B TNFRSF6 TNFSF10 TNFSF6 TRADD TRAF2 TRAIL TRAILR1 TRAILR2 TRAP3 TRICK2 ZTNFR9	Homo sapiens (human)
Ligand-dependent caspase activation	Caspase-8 FAS-associated death domain protein FLICE inhibitory protein Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Receptor-interacting serine/threonine-protein kinase 1 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 TNF receptor-associated factor 2 Toll-like receptor 4 Tumor necrosis factor ligand superfamily member 10 Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor type 1-associated DEATH domain protein Viral CASP8 and FADD-like apoptosis regulator	O00206 O00220 O14763 P08571 P25445 P48023 P50591 Q12933 Q13158 Q13546 Q14790 Q15628 Q76RF1 Q86XR7 Q8IUC6 Q98325 Q9Y6Y9	APO2 APO2L APT1 APT1LG1 CASP8 CD14 CD95L DR4 DR5 ESOP1 FADD FAS FAS1 FASL FASLG KILLER LY96 MC159L MCH5 MD2 MORT1 ORF71 PRVTIRB RIP RIP1 RIPK1 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TNFRSF10A TNFRSF10B TNFRSF6 TNFSF10 TNFSF6 TRADD TRAF2 TRAIL TRAILR1 TRAILR2 TRAM TRAP3 TRICK2 TRIF ZTNFR9	Homo sapiens (human)
Sodium/Proton exchangers	Sodium/hydrogen exchanger 1 Sodium/hydrogen exchanger 2 Sodium/hydrogen exchanger 3 Sodium/hydrogen exchanger 4 Sodium/hydrogen exchanger 5 Sodium/hydrogen exchanger 6 Sodium/hydrogen exchanger 7 Sodium/hydrogen exchanger 8 Sodium/hydrogen exchanger 9	P19634 P48764 Q14940 Q6AI14 Q8IVB4 Q92581 Q96T83 Q9UBY0 Q9Y2E8	APNH1 KIAA0267 KIAA0939 NHE1 NHE2 NHE3 NHE4 NHE5 NHE6 NHE7 NHE8 NHE9 SLC9A1 SLC9A2 SLC9A3 SLC9A4 SLC9A5 SLC9A6 SLC9A7 SLC9A8 SLC9A9	Homo sapiens (human)
Hyaluronan uptake and degradation	Beta-glucuronidase Beta-hexosaminidase subunit alpha Beta-hexosaminidase subunit beta CD44 antigen Calcineurin B homologous protein 1 Hyaluronan mediated motility receptor Hyaluronidase-1 Hyaluronidase-2 Hyaluronidase-3 Lymphatic vessel endothelial hyaluronic acid receptor 1 Sodium/hydrogen exchanger 1 Stabilin-2	O43820 O75330 P06865 P07686 P08236 P16070 P19634 Q12794 Q12891 Q8WWQ8 Q99653 Q9Y5Y7	APNH1 CD44 CHP CHP1 CRSBP1 FEEL2 FELL FEX2 GUSB HAR HARE HEXA HEXB HMMR HYAL1 HYAL2 HYAL3 IHABP LHR LUCA1 LUCA2 LUCA3 LYVE1 MDU2 MDU3 MIC4 NHE1 RHAMM SLC9A1 STAB2 XLKD1	Homo sapiens (human)	G35674CY
Deposition of new CENPA-containing nucleosomes at the centromere	Centromere protein C Centromere protein H Centromere protein I Centromere protein K Centromere protein L Centromere protein M Centromere protein N Centromere protein O Centromere protein P Centromere protein Q Centromere protein R Centromere protein S Centromere protein T Centromere protein U Centromere protein W Centromere protein X Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3-like centromeric protein A Histone H4 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Holliday junction recognition protein Kinetochore scaffold 1 Mis18-binding protein 1 Nucleophosmin Protein Mis18-alpha Protein Mis18-beta Remodeling and spacing factor 1 RuvB-like 1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5	A8MT69 O43482 O60264 O60814 P04908 P06748 P06899 P0C5Y9 P16104 P20671 P23527 P33778 P49450 P57053 P58876 P62805 P62807 Q03188 Q09028 Q13352 Q16576 Q16777 Q16778 Q5EE01 Q6FI13 Q6IPU0 Q6P0N0 Q71F23 Q71UI9 Q7L2Z9 Q8N0S6 Q8N257 Q8N2Z9 Q8NCD3 Q8NG31 Q92674 Q93077 Q93079 Q96A08 Q96BT3 Q96H22 Q96T23 Q99877 Q99878 Q99879 Q99880 Q9BS16 Q9BTM1 Q9BU64 Q9H3R5 Q9NSP4 Q9NYP9 Q9Y265	APITD1 C14orf106 C16orf56 C16orf60 C1orf155 C21orf45 C21orf46 C22orf18 C6orf139 C6orf173 CASC5 CENPA CENPC CENPC1 CENPH CENPI CENPK CENPL CENPM CENPN CENPO CENPP CENPQ CENPR CENPS CENPT CENPU CENPW CENPX CUG2 FAAP10 FAAP16 FAKTS FASP1 FLEG1 FSHPRH1 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HBXAP HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 HJURP ICEN19 ICEN22 ICEN24 ICEN32 ICEN33 ICEN35 ICEN36 ICEN37 ICEN39 ICEN7 INO80H ITGB3BP KIAA1570 KIAA1903 KLIP1 KNL1 KNL2 LRPR1 M18BP1 MCM21R MHF1 MHF2 MIS18A MIS18B MIS18BP1 MLF1IP NMP238 NPM NPM1 NRIF3 OIP5 PANE1 PBIP1 RBAP46 RBAP48 RBBP4 RBBP7 RSF1 RUVBL1 SMARCA5 SNF2H STRA13 TIP49 TIP49A TSH2B URLC9 WCRF135 XAP8	Homo sapiens (human)
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	Apoptosis facilitator Bcl-2-like protein 14 Apoptosis-stimulating of p53 protein 1 Apoptosis-stimulating of p53 protein 2 B-cell lymphoma 6 protein Baculoviral IAP repeat-containing protein 5 Cellular tumor antigen p53 Geranylgeranyl transferase type-2 subunit alpha Geranylgeranyl transferase type-2 subunit beta Protein NDRG1 Quinone oxidoreductase PIG3 Rab proteins geranylgeranyltransferase component A 1 Tumor protein 63 Tumor protein p73 p53 apoptosis effector related to PMP-22	O15350 O15392 P04637 P24386 P41182 P53611 Q13625 Q53FA7 Q92597 Q92696 Q96FX8 Q96KQ4 Q9BZR8 Q9H3D4	API4 ASPP1 ASPP2 BBP BCL2L14 BCL5 BCL6 BCLG BIRC5 CAP43 CHM DRG1 GGTB IAP4 KCP1 KET KIAA0771 KRTCAP1 LAZ3 NDRG1 P53 P63 P73 P73H P73L PERP PIG3 PIGPC1 PPP1R13B RABGGTA RABGGTB REP1 RTP TCD THW TP53 TP53BP2 TP53I3 TP63 TP73 TP73L ZBTB27 ZNF51	Homo sapiens (human)
Regulation of PTEN localization	E3 ubiquitin-protein ligase NEDD4 E3 ubiquitin-protein ligase XIAP Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Polyubiquitin-B Polyubiquitin-C Protein PML Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P0CG47 P0CG48 P29590 P46934 P60484 P62979 P62987 P98170 Q93009	API3 BIRC4 HAUSP IAP3 KIAA0093 MMAC1 MYL NEDD4 NEDD4-1 PML PP8675 PTEN RNF71 RPF1 RPS27A TEP1 TRIM19 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 USP7 XIAP	Homo sapiens (human)
SMAC, XIAP-regulated apoptotic response	Caspase-3 Caspase-7 Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP	P42574 P55210 P98170 Q9NR28	API3 BIRC4 CASP3 CASP7 CPP32 DIABLO IAP3 MCH3 SMAC XIAP	Homo sapiens (human)
TICAM1, RIP1-mediated IKK complex recruitment	Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta NF-kappa-B essential modulator Polyubiquitin-B Polyubiquitin-C Receptor-interacting serine/threonine-protein kinase 1 Receptor-interacting serine/threonine-protein kinase 3 TIR domain-containing adapter molecule 1 TNF receptor-associated factor 6 Toll-like receptor 3 Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14920 O15111 O15455 P0CG47 P0CG48 P51668 P61077 P61088 P62837 P62979 P62987 Q13404 Q13489 Q13490 Q13546 Q8IUC6 Q9Y4K3 Q9Y572 Q9Y6K9	API1 API2 BIRC2 BIRC3 BLU CHUK CROC1 FIP3 IKBKB IKBKG IKKA IKKB MIHB MIHC NEMO PRVTIRB PUBC1 RIP RIP1 RIP3 RIPK1 RIPK3 RNF48 RNF49 RNF85 RPS27A SFT TCF16 TICAM1 TLR3 TRAF6 TRIF UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBC5C UBCEP1 UBCEP2 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBE2D1 UBE2D2 UBE2D3 UBE2N UBE2V UBE2V1 UEV1	Homo sapiens (human)
IKK complex recruitment mediated by RIP1	Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Lymphocyte antigen 96 Monocyte differentiation antigen CD14 NF-kappa-B essential modulator Polyubiquitin-B Polyubiquitin-C Receptor-interacting serine/threonine-protein kinase 1 Receptor-interacting serine/threonine-protein kinase 3 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 TNF receptor-associated factor 6 Toll-like receptor 4 Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00206 O14920 O15111 P08571 P0CG47 P0CG48 P51668 P61077 P61088 P62837 P62979 P62987 Q13404 Q13489 Q13490 Q13546 Q86XR7 Q8IUC6 Q9Y4K3 Q9Y572 Q9Y6K9 Q9Y6Y9	API1 API2 BIRC2 BIRC3 BLU CD14 CHUK CROC1 ESOP1 FIP3 IKBKB IKBKG IKKA IKKB LY96 MD2 MIHB MIHC NEMO PRVTIRB PUBC1 RIP RIP1 RIP3 RIPK1 RIPK3 RNF48 RNF49 RNF85 RPS27A SFT TCF16 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAF6 TRAM TRIF UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBC5C UBCEP1 UBCEP2 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBE2D1 UBE2D2 UBE2D3 UBE2N UBE2V UBE2V1 UEV1	Homo sapiens (human)
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 CD40 ligand Lymphotoxin-alpha Lymphotoxin-beta Mitogen-activated protein kinase kinase kinase 14 TNF receptor-associated factor 2 TNF receptor-associated factor 3 Tumor necrosis factor ligand superfamily member 11 Tumor necrosis factor ligand superfamily member 12 Tumor necrosis factor ligand superfamily member 13B Tumor necrosis factor ligand superfamily member 14 Tumor necrosis factor receptor superfamily member 11A Tumor necrosis factor receptor superfamily member 12A Tumor necrosis factor receptor superfamily member 13C Tumor necrosis factor receptor superfamily member 3	O14788 O43508 O43557 P01374 P29965 P36941 Q06643 Q12933 Q13114 Q13489 Q13490 Q96RJ3 Q99558 Q9NP84 Q9Y275 Q9Y6Q6	API1 API2 APO3L BAFF BAFFR BIRC2 BIRC3 BLYS BR3 CAP-1 CD40L CD40LG CRAF1 D12S370 DR3LG FN14 HVEML LIGHT LTA LTB LTBR MAP3K14 MIHB MIHC NIK OPGL RANK RANKL RNF48 RNF49 TALL1 TNFB TNFC TNFCR TNFR3 TNFRSF11A TNFRSF12A TNFRSF13C TNFRSF3 TNFSF1 TNFSF11 TNFSF12 TNFSF13B TNFSF14 TNFSF20 TNFSF3 TNFSF5 TRAF2 TRAF3 TRAFAMN TRANCE TRAP TRAP3 ZTNF4	Homo sapiens (human)
TNFR2 non-canonical NF-kB pathway	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 CD40 ligand Lymphotoxin-alpha Lymphotoxin-beta Mitogen-activated protein kinase kinase kinase 14 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 TNF receptor-associated factor 2 TNF receptor-associated factor 3 Tumor necrosis factor ligand superfamily member 11 Tumor necrosis factor ligand superfamily member 12 Tumor necrosis factor ligand superfamily member 13B Tumor necrosis factor ligand superfamily member 14 Tumor necrosis factor receptor superfamily member 11A Tumor necrosis factor receptor superfamily member 12A Tumor necrosis factor receptor superfamily member 13C Tumor necrosis factor receptor superfamily member 1B Tumor necrosis factor receptor superfamily member 3 Tumor necrosis factor	A5LHX3 O00231 O00232 O00233 O00487 O14788 O14818 O43242 O43508 O43557 O75832 P01374 P01375 P17980 P20333 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P29965 P35998 P36941 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 Q06323 Q06643 Q12933 Q13114 Q13200 Q13489 Q13490 Q14997 Q15008 Q16401 Q8TAA3 Q92530 Q96RJ3 Q99436 Q99460 Q99558 Q9NP84 Q9UL46 Q9UNM6 Q9Y275 Q9Y6Q6	API1 API2 APO3L BAFF BAFFR BIRC2 BIRC3 BLYS BR3 C7orf76 CAP-1 CD40L CD40LG CRAF1 D12S370 DR3LG DSS1 FN14 HC2 HC3 HC8 HC9 HSPC HVEML IFI5111 KIAA0072 KIAA0077 KIAA0107 LIGHT LMP10 LMP2 LMP7 LMPX LMPY LTA LTB LTBR MAP3K14 MB1 MCB1 MECL1 MIHB MIHC MIP224 MOV34L MSS1 NIK NU OPGL PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RANK RANKL RING10 RING12 RNF48 RNF49 SEM1 SHFDG1 SHFM1 SUG1 SUG2 TALL1 TBP1 TBP7 TNF TNFA TNFB TNFBR TNFC TNFCR TNFR2 TNFR3 TNFRSF11A TNFRSF12A TNFRSF13C TNFRSF1B TNFRSF3 TNFSF1 TNFSF11 TNFSF12 TNFSF13B TNFSF14 TNFSF2 TNFSF20 TNFSF3 TNFSF5 TRAF2 TRAF3 TRAFAMN TRANCE TRAP TRAP2 TRAP3 X Y Y2 Z ZTNF4	Homo sapiens (human)
TNFR1-induced NF-kappa-B signaling pathway	Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 E3 ubiquitin-protein ligase RNF31 E3 ubiquitin-protein ligase XIAP Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator OTU domain-containing protein 1 OTU domain-containing protein 7B Optineurin RanBP-type and C3HC4-type zinc finger-containing protein 1 Receptor-interacting serine/threonine-protein kinase 1 Sharpin Small ribosomal subunit protein RACK1 Spermatogenesis-associated protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 1 TNF receptor-associated factor 2 Tumor necrosis factor alpha-induced protein 3 Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor Ubiquitin carboxyl-terminal hydrolase 21 Ubiquitin carboxyl-terminal hydrolase 2 Ubiquitin carboxyl-terminal hydrolase 4 Ubiquitin carboxyl-terminal hydrolase CYLD	O14920 O15111 O43318 O75604 P01375 P19438 P21580 P63244 P98170 Q12933 Q13077 Q13107 Q13489 Q13490 Q13546 Q15628 Q15750 Q5VV17 Q6GQQ9 Q8N5C8 Q96CV9 Q96EP0 Q9BYM8 Q9H0F6 Q9NQC7 Q9NYJ8 Q9UK80 Q9UM82 Q9Y6K9	API1 API2 API3 BIRC2 BIRC3 BIRC4 C20orf18 CHUK CYLD CYLD1 DUBA7 EBI6 FIP2 FIP3 GLC1E GNB2L1 HIP7 HYPL IAP3 IKBKB IKBKG IKKA IKKB KIAA0733 KIAA0757 KIAA0849 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MIHB MIHC NEMO NRP OPTN OTDC1 OTUD1 OTUD7B OTUD7C PD1 RACK1 RBCK1 RIP RIP1 RIPK1 RNF31 RNF48 RNF49 RNF54 SHARPIN SIPL1 SPATA2 TAB1 TAB2 TAB3 TAK1 TCF16 TNF TNFA TNFAIP3 TNFAR TNFR1 TNFRSF1A TNFSF2 TRADD TRAF1 TRAF2 TRAP3 UBCE7IP3 UBP41 UNP UNPH USP2 USP21 USP23 USP4 XAP3 XAP4 XIAP ZA20D1 ZIBRA	Homo sapiens (human)

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