GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1276 - 1300** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Signaling by Insulin receptor	Insulin receptor Insulin	P01308 P06213	INS INSR	Homo sapiens (human)
Signaling by ERBB4	Disks large homolog 4 Epidermal growth factor receptor Gamma-aminobutyric acid receptor subunit alpha-1 Gamma-aminobutyric acid receptor subunit beta-1 Gamma-aminobutyric acid receptor subunit beta-2 Gamma-aminobutyric acid receptor subunit beta-3 Gamma-aminobutyric acid receptor subunit gamma-2 Gamma-aminobutyric acid receptor subunit gamma-3 Gamma-aminobutyric acid receptor subunit theta Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor	O14511 O14944 P00533 P01133 P14867 P18505 P18507 P28472 P35070 P47870 P56975 P78352 Q02297 Q8WWG1 Q99075 Q99928 Q9UN88	BTC DLG4 DTR DTS EGF EGFR ERBB ERBB1 EREG GABRA1 GABRB1 GABRB2 GABRB3 GABRG2 GABRG3 GABRQ GGF HBEGF HEGFL HER1 HGL HRGA NDF NRG1 NRG2 NRG3 NRG4 NTAK PSD95 SMDF	Homo sapiens (human)
Highly calcium permeable nicotinic acetylcholine receptors	Acetylcholine receptor subunit alpha Neuronal acetylcholine receptor subunit alpha-2 Neuronal acetylcholine receptor subunit alpha-3 Neuronal acetylcholine receptor subunit alpha-4 Neuronal acetylcholine receptor subunit alpha-5 Neuronal acetylcholine receptor subunit alpha-6 Neuronal acetylcholine receptor subunit beta-2 Neuronal acetylcholine receptor subunit beta-3 Neuronal acetylcholine receptor subunit beta-4	P02708 P17787 P30532 P30926 P32297 P43681 Q05901 Q15822 Q15825	ACHRA CHNRA CHRNA1 CHRNA2 CHRNA3 CHRNA4 CHRNA5 CHRNA6 CHRNB2 CHRNB3 CHRNB4 NACHRA3 NACHRA5 NACRA4	Homo sapiens (human)
Acetylcholine Neurotransmitter Release Cycle	Choline O-acetyltransferase Complexin-1 High affinity choline transporter 1 Liprin-alpha-1 Liprin-alpha-2 Liprin-alpha-3 Liprin-alpha-4 Peripheral-type benzodiazepine receptor-associated protein 1 Protein unc-13 homolog B Ras-related protein Rab-3A Regulating synaptic membrane exocytosis protein 1 Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Vesicle-associated membrane protein 2 Vesicular acetylcholine transporter	O14795 O14810 O75145 O75334 O75335 O95153 P20336 P21579 P28329 P60880 P63027 Q13136 Q16572 Q16623 Q86UR5 Q9GZV3	BZRAP1 CHAT CHT1 CPLX1 KIAA0340 KIAA0612 KIAA0654 KIAA0897 LIP1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 RAB3A RAB3IP2 RBP1 RIM1 RIMBP1 RIMS1 SLC18A3 SLC5A7 SNAP SNAP25 STX1 STX1A SVP65 SYB2 SYT SYT1 TSPOAP1 UNC13 UNC13B VACHT VAMP2	Homo sapiens (human)
CLEC7A/inflammasome pathway	Apoptosis-associated speck-like protein containing a CARD Caspase-8 Interleukin-1 beta Mucosa-associated lymphoid tissue lymphoma translocation protein 1 Nuclear factor NF-kappa-B p105 subunit Transcription factor p65	P01584 P19838 Q04206 Q14790 Q9UDY8 Q9ULZ3	ASC CARD5 CASP8 IL1B IL1F2 MALT1 MCH5 MLT NFKB1 NFKB3 PYCARD RELA TMS1	Homo sapiens (human)
Peptide hormone biosynthesis	Neuroendocrine convertase 1 Pro-opiomelanocortin	P01189 P29120	NEC1 PCSK1 POMC	Homo sapiens (human)
Glucagon signaling in metabolic regulation	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Glucagon receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein subunit beta-4 Pro-glucagon	O43306 O60262 O60266 O60503 O95622 P01275 P16520 P40145 P47871 P50150 P50151 P51828 P59768 P61952 P62873 P62879 P63092 P63215 P63218 Q08462 Q08828 Q5JWF2 Q8NFM4 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 GCG GCGR GNAS GNAS1 GNB1 GNB2 GNB3 GNB4 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT10 GNGT11 GNGT3 GNGT4 GNGT5 GNGT7 GNGT9 GSP KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060	Homo sapiens (human)
Tyrosine catabolism	4-hydroxyphenylpyruvate dioxygenase Fumarylacetoacetase Homogentisate 1,2-dioxygenase Maleylacetoacetate isomerase Tyrosine aminotransferase	O43708 P16930 P17735 P32754 Q93099	FAH GSTZ1 HGD HGO HPD MAAI PPD TAT	Homo sapiens (human)
IRS activation	Growth factor receptor-bound protein 10 Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor Insulin	P01308 P06213 P35568 Q13322 Q9Y4H2	GRB10 GRBIR INS INSR IRS1 IRS2 KIAA0207	Homo sapiens (human)
Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA)	Band 3 anion transport protein	P02730	AE1 DI EPB3 SLC4A1	Homo sapiens (human)
Unblocking of NMDA receptors, glutamate binding and activation	Alpha-actinin-2 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Disks large homolog 1 Disks large homolog 2 Disks large homolog 3 Disks large homolog 4 Glutamate receptor 1 Glutamate receptor 2 Glutamate receptor 3 Glutamate receptor 4 Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2A Glutamate receptor ionotropic, NMDA 2B Glutamate receptor ionotropic, NMDA 2C Glutamate receptor ionotropic, NMDA 2D Leucine-rich repeat-containing protein 7 Neurofilament light polypeptide	O15399 P07196 P0DP23 P35609 P42261 P42262 P42263 P48058 P78352 Q05586 Q12879 Q12959 Q13224 Q13554 Q13555 Q13557 Q14957 Q15700 Q92796 Q96NW7 Q9UQM7	ACTN2 CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG DLG1 DLG2 DLG3 DLG4 GLUA1 GLUH1 GLUR1 GLUR2 GLUR3 GLUR4 GLURC GRIA1 GRIA2 GRIA3 GRIA4 GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D GluA2 GluA3 GluA4 GluN2D KIAA0968 KIAA1232 KIAA1365 LAP1 LRRC7 NEFL NF68 NFL NMDAR1 NMDAR2A NMDAR2B NMDAR2C NMDAR2D PSD95	Homo sapiens (human)
LXRs regulate gene expression linked to cholesterol transport and efflux	ADP-ribosylation factor-like protein 4C ATP-binding cassette sub-family G member 1 ATP-binding cassette sub-family G member 5 ATP-binding cassette sub-family G member 8 Apolipoprotein C-I Apolipoprotein C-II Apolipoprotein C-IV Apolipoprotein D Apolipoprotein E Cholesteryl ester transfer protein Endonuclease/exonuclease/phosphatase family domain-containing protein 1 F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 G protein pathway suppressor 2 Helicase MOV-10 Histone acetyltransferase p300 Histone deacetylase 3 Lysine-specific demethylase 3A Lysine-specific demethylase 4A Lysine-specific histone demethylase 1A Lysine-specific histone demethylase 2 Nuclear receptor coactivator 1 Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 Oxysterols receptor LXR-alpha Oxysterols receptor LXR-beta Phospholipid-transporting ATPase ABCA1 Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Retinoic acid receptor RXR-alpha Retinoic acid receptor RXR-beta Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein	O15379 O60341 O60907 O75164 O75376 O95477 P02649 P02654 P02655 P05090 P11597 P19793 P28702 P45844 P55055 P55056 P56559 Q09472 Q13133 Q13227 Q15788 Q7L9B9 Q8NB78 Q8NDV7 Q9BZK7 Q9H221 Q9H222 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9UKV8 Q9UL18 Q9UPQ9 Q9Y4C1 Q9Y618	ABC1 ABC8 ABCA1 ABCG1 ABCG5 ABCG8 AGO1 AGO2 AGO3 AGO4 AOF1 AOF2 APC2 APOC1 APOC2 APOC4 APOD APOE ARL4C ARL7 BHLHE74 C6orf193 CAGH26 CERP CETP CTG26 EEPD1 EIF2C1 EIF2C2 EIF2C3 EIF2C4 EP300 GPS2 HDAC3 IRA1 JHDM2A JHDM3A JMJD1 JMJD1A JMJD2 JMJD2A KDM1 KDM1A KDM1B KDM3A KDM4A KIAA0601 KIAA0677 KIAA0742 KIAA1047 KIAA1093 KIAA1460 KIAA1567 KIAA1582 KIAA1631 KIAA1706 LSD1 LSD2 LXRA LXRB MOV10 NCOA1 NCOR1 NCOR2 NER NR1H2 NR1H3 NR2B1 NR2B2 P300 RXRA RXRB SRC1 TBL1 TBL1X TBL1XR1 TBLR1 TNRC6 TNRC6A TNRC6B TNRC6C TSGA UNR WHT1	Homo sapiens (human)
Epithelial-Mesenchymal Transition (EMT) during gastrulation	Eomesodermin homolog Fibroblast growth factor receptor 1 T-box transcription factor T Zinc finger protein SNAI1	O15178 O95863 O95936 P11362	BFGFR CEK EOMES FGFBR FGFR1 FLG FLT2 HBGFR SNAH SNAI1 T TBR2 TBXT	Homo sapiens (human)
Defective UGT1A1 causes hyperbilirubinemia	UDP-glucuronosyltransferase 1A1	P22309	GNT1 UGT1 UGT1A1	Homo sapiens (human)
NrCAM interactions	Ankyrin-1 Contactin-2 Disks large homolog 1 Disks large homolog 3 Disks large homolog 4 Neuronal cell adhesion molecule Neuropilin-2	O60462 P16157 P78352 Q02246 Q12959 Q92796 Q92823	ANK ANK1 AXT CNTN2 DLG1 DLG3 DLG4 KIAA0343 KIAA1232 NRCAM NRP2 PSD95 TAG1 TAX1 VEGF165R2	Homo sapiens (human)
Defective DPAGT1 causes CDG-1j, CMSTA2	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	Q9H3H5	DPAGT1 DPAGT2	Homo sapiens (human)
Defective SLC29A3 causes histiocytosis-lymphadenopathy plus syndrome (HLAS)	Equilibrative nucleoside transporter 3	Q9BZD2	ENT3 SLC29A3	Homo sapiens (human)
Inactivation of CSF3 (G-CSF) signaling	Cullin-5 Elongin-B Elongin-C Granulocyte colony-stimulating factor receptor Granulocyte colony-stimulating factor Non-receptor tyrosine-protein kinase TYK2 Polyubiquitin-B Polyubiquitin-C RING-box protein 2 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase HCK Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14543 O15524 O60674 P07948 P08631 P09919 P0CG47 P0CG48 P23458 P29597 P40763 P42224 P42229 P43405 P51668 P51692 P61077 P62837 P62979 P62987 Q15369 Q15370 Q93034 Q99062 Q9UBF6	APRF C17orf33 CIS3 CSF3 CSF3R CUL5 ELOB ELOC GCSF GCSFR HCK JAK1 JAK1A JAK1B JAK2 JTK8 LYN PUBC1 RBX2 RNF7 ROC2 RPS27A SAG SFT SOCS1 SOCS3 SSI1 SSI3 STAT1 STAT3 STAT5 STAT5A STAT5B SYK TCEB1 TCEB2 TIP3 TYK2 UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBC5C UBCEP1 UBCEP2 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBE2D1 UBE2D2 UBE2D3 VACM1	Homo sapiens (human)
Activation of the pre-replicative complex	Cell division control protein 45 homolog Cell division control protein 6 homolog Cell division cycle 7-related protein kinase Cyclin-dependent kinase 2 DNA helicase MCM8 DNA polymerase alpha catalytic subunit DNA polymerase alpha subunit B DNA polymerase epsilon catalytic subunit A DNA polymerase epsilon subunit 2 DNA polymerase epsilon subunit 3 DNA polymerase epsilon subunit 4 DNA primase large subunit DNA primase small subunit DNA replication factor Cdt1 DNA replication licensing factor MCM2 DNA replication licensing factor MCM3 DNA replication licensing factor MCM4 DNA replication licensing factor MCM5 DNA replication licensing factor MCM6 DNA replication licensing factor MCM7 Geminin Origin recognition complex subunit 1 Origin recognition complex subunit 2 Origin recognition complex subunit 3 Origin recognition complex subunit 4 Origin recognition complex subunit 5 Origin recognition complex subunit 6 Protein DBF4 homolog A Protein MCM10 homolog Replication protein A 14 kDa subunit Replication protein A 30 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit	O00311 O43913 O43929 O75419 O75496 P09884 P15927 P24941 P25205 P27694 P33991 P33992 P33993 P35244 P49642 P49643 P49736 P56282 Q07864 Q13156 Q13415 Q13416 Q14181 Q14566 Q7L590 Q99741 Q9H211 Q9NR33 Q9NRF9 Q9UBD5 Q9UBU7 Q9UJA3 Q9Y5N6	ASK BM28 C20orf154 CCNL1 CDC18L CDC21 CDC45 CDC45L CDC45L2 CDC46 CDC47 CDC6 CDC7 CDC7L1 CDCL1 CDK2 CDKN2 CDT1 CHRAC17 DBF4 DBF4A DPE2 GMNN KIAA0030 LATHEO MCM10 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MCM8 ORC1 ORC1L ORC2 ORC2L ORC3 ORC3L ORC4 ORC4L ORC5 ORC5L ORC6 ORC6L PARC1 POLA POLA1 POLA2 POLE POLE1 POLE2 POLE3 POLE4 PRIM1 PRIM2 PRIM2A REPA1 REPA2 REPA3 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA4 RPA70 ZDBF1	Homo sapiens (human)
O-linked glycosylation	Beta-1,4-glucuronyltransferase 1 Dystroglycan 1 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 Protein O-mannose kinase Protein O-mannosyl-transferase 1 Protein O-mannosyl-transferase 2 UDP-GalNAc Xylosyl- and glucuronyltransferase LARGE1 Xylosyl- and glucuronyltransferase LARGE2	O43505 O95461 Q14118 Q8N3Y3 Q8NAT1 Q8NCR0 Q8WZA1 Q9H5K3 Q9UKY4 Q9Y6A1	AGO61 B3GALNT2 B3GNT1 B3GNT6 B4GAT1 C3orf39 DAG1 EOGTL GTDC2 GYLTL1B KIAA0609 LARGE LARGE1 LARGE2 MGAT1.2 POMGNT1 POMGNT2 POMK POMT1 POMT2 SGK196	Homo sapiens (human)
Activation of BMF and translocation to mitochondria	Bcl-2-modifying factor Dynein light chain 2, cytoplasmic Mitogen-activated protein kinase 8	P45983 Q96FJ2 Q96LC9	BMF DLC2 DYNLL2 JNK1 MAPK8 PRKM8 SAPK1 SAPK1C	Homo sapiens (human)
Sorafenib-resistant KIT mutants	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Signaling by TCF7L2 mutants	C-terminal-binding protein 1 C-terminal-binding protein 2 Transcription factor 7-like 2	P56545 Q13363 Q9NQB0	CTBP CTBP1 CTBP2 TCF4 TCF7L2	Homo sapiens (human)
Chylomicron remodeling	Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-IV Apolipoprotein A-V Apolipoprotein B-100 Apolipoprotein C-II Apolipoprotein C-III Apolipoprotein E Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 Lipoprotein lipase	P02647 P02649 P02652 P02655 P02656 P04114 P06727 P06858 Q6Q788 Q8IV16	APC2 APOA1 APOA2 APOA4 APOA5 APOB APOC2 APOC3 APOE GPIHBP1 HBP1 LIPD LPL RAP3	Homo sapiens (human)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 Free fatty acid receptor 1 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha-15	O14842 O95837 P29992 P30679 P50148 Q00722 Q01970 Q9NQ66	FFAR1 GA11 GAQ GNA11 GNA14 GNA15 GNA16 GNAQ GPR40 KIAA0581 PLCB1 PLCB2 PLCB3	Homo sapiens (human)

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