EGFR downregulation
|
|
|
- AF1P
- AREG
- AREGB
- ARHGEF7
- BTC
- CBL
- CBL2
- CDC42
- CIN85
- CNSA1
- CNSA2
- CNSA3
- COOL1
- DTR
- DTS
- EGF
- EGFR
- EPGN
- EPN1
- EPS15
- EPS15L1
- EPS15R
- ERBB
- ERBB1
- EREG
- HBEGF
- HBP
- HEGFL
- HER1
- HGS
- HRS
- KIAA0142
- P85SPR
- PAK3BP
- PIXB
- PTPH1
- PTPK
- PTPN12
- PTPN3
- PTPRK
- RNF55
- RPS27A
- SDGF
- SH3D2A
- SH3D2B
- SH3D2C
- SH3GL1
- SH3GL2
- SH3GL3
- SH3KBP1
- SPRY1
- SPRY2
- STAM
- STAM1
- STAM2
- TGFA
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
|
|
Transcriptional activation of mitochondrial biogenesis
|
- 3'-5' exoribonuclease HELZ2
- 5-aminolevulinate synthase, non-specific, mitochondrial
- ATP synthase subunit beta, mitochondrial
- Acetyl-coenzyme A synthetase, cytoplasmic
- CREB-binding protein
- CREB-regulated transcription coactivator 1
- CREB-regulated transcription coactivator 2
- CREB-regulated transcription coactivator 3
- Calcium/calmodulin-dependent protein kinase type IV
- Calmodulin-1
- Chromodomain-helicase-DNA-binding protein 9
- Cyclic AMP-dependent transcription factor ATF-2
- Cytochrome c
- DNA polymerase subunit gamma-2
- DNA-directed RNA polymerase, mitochondrial
- Dimethyladenosine transferase 1, mitochondrial
- Dimethyladenosine transferase 2, mitochondrial
- F-box-like/WD repeat-containing protein TBL1X
- F-box-like/WD repeat-containing protein TBL1XR1
- GA-binding protein alpha chain
- Glutamate dehydrogenase 1, mitochondrial
- Glutamate dehydrogenase 2, mitochondrial
- Histone deacetylase 3
- Histone-arginine methyltransferase CARM1
- Host cell factor 1
- Isocitrate dehydrogenase [NADP], mitochondrial
- Mediator of RNA polymerase II transcription subunit 1
- Myocyte-specific enhancer factor 2C
- Myocyte-specific enhancer factor 2D
- NAD-dependent protein deacetylase sirtuin-3, mitochondrial
- NAD-dependent protein deacylase sirtuin-5, mitochondrial
- NAD-dependent protein lipoamidase sirtuin-4, mitochondrial
- Nuclear receptor coactivator 1
- Nuclear receptor coactivator 2
- Nuclear receptor coactivator 6
- Nuclear receptor corepressor 1
- Nuclear receptor subfamily 1 group D member 1
- Nuclear respiratory factor 1
- PGC-1 and ERR-induced regulator in muscle protein 1
- Peroxisome proliferator-activated receptor alpha
- Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
- Peroxisome proliferator-activated receptor gamma coactivator 1-beta
- Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
- Retinoic acid receptor RXR-alpha
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3
- Single-stranded DNA-binding protein, mitochondrial
- Steroid hormone receptor ERR1
- Superoxide dismutase [Mn], mitochondrial
- Transcription factor A, mitochondrial
- Transcription termination factor 1, mitochondrial
- Trimethylguanosine synthase
- Twinkle mtDNA helicase
|
|
- ACAS2
- ACSS2
- AIB3
- ALAS1
- ALAS3
- ALASH
- ARC205
- ATF2
- ATP5B
- ATP5F1B
- ATPMB
- ATPSB
- BAF60C
- BHLHE74
- BHLHE75
- C10orf2
- C1orf170
- CALM
- CALM1
- CAM
- CAM1
- CAMK
- CAMK-GR
- CAMK4
- CAMKIV
- CARM1
- CBP
- CHD9
- CREB2
- CREBBP
- CREBP1
- CRSP1
- CRSP200
- CRTC1
- CRTC2
- CRTC3
- CYC
- CYCS
- DRIP205
- DRIP230
- E4TF1A
- EAR1
- ERR1
- ESRL1
- ESRRA
- GABPA
- GLUD
- GLUD1
- GLUD2
- GLUDP1
- HCA137
- HCF1
- HCFC1
- HDAC3
- HELZ2
- HFC1
- HREV
- IDH2
- IRA1
- KIAA0181
- KIAA0308
- KIAA0595
- KIAA0616
- KIAA1047
- KIAA1769
- KISH2
- LEM6
- MECT1
- MED1
- MEF2C
- MEF2D
- MTERF
- MTERF1
- MTPOLB
- NCOA1
- NCOA2
- NCOA6
- NCOA6IP
- NCOR1
- NR1C1
- NR1D1
- NR2B1
- NR3B1
- NRF1
- NS5ATP5
- PBP
- PEO1
- PERC
- PERM1
- PGC1
- PGC1A
- PGC1B
- PIMT
- POLG2
- POLRMT
- PPAR
- PPARA
- PPARBP
- PPARGBP
- PPARGC1
- PPARGC1A
- PPARGC1B
- PPRC1
- PRIC285
- PRIC320
- PRMT4
- RAP250
- RB18A
- RXRA
- SIR2L3
- SIR2L4
- SIR2L5
- SIRT3
- SIRT4
- SIRT5
- SMARCD3
- SOD2
- SRC1
- SRC2
- SSBP
- SSBP1
- TBL1
- TBL1X
- TBL1XR1
- TBLR1
- TCF6
- TCF6L2
- TFAM
- TFB1M
- TFB2M
- TGS1
- THRAL
- TIF2
- TORC1
- TORC2
- TORC3
- TRAP220
- TRBP
- TRIP2
- TWNK
- WAMTP1
|
|
Defective F8 binding to von Willebrand factor
|
|
|
|
|
Condensation of Prophase Chromosomes
|
|
|
- CAPC
- CAPD3
- CAPE
- CAPH2
- CCNB
- CCNB1
- CDC2
- CDC28A
- CDK1
- CDKN1
- H2AB1
- H2AC14
- H2AC18
- H2AC19
- H2AC20
- H2AC4
- H2AC6
- H2AC7
- H2AC8
- H2AFA
- H2AFB1
- H2AFE
- H2AFG
- H2AFJ
- H2AFL
- H2AFM
- H2AFO
- H2AFQ
- H2AFV
- H2AFX
- H2AJ
- H2AV
- H2AX
- H2AZ2
- H2BC1
- H2BC10
- H2BC11
- H2BC12
- H2BC12L
- H2BC13
- H2BC14
- H2BC15
- H2BC17
- H2BC21
- H2BC26
- H2BC3
- H2BC4
- H2BC5
- H2BC6
- H2BC7
- H2BC8
- H2BC9
- H2BFA
- H2BFB
- H2BFC
- H2BFD
- H2BFE
- H2BFF
- H2BFG
- H2BFH
- H2BFJ
- H2BFK
- H2BFL
- H2BFN
- H2BFQ
- H2BFR
- H2BFS
- H2BFT
- H2BS1
- H2BU1
- H3-3A
- H3-3B
- H3-4
- H3.3A
- H3.3B
- H3C1
- H3C10
- H3C11
- H3C12
- H3C13
- H3C14
- H3C15
- H3C2
- H3C3
- H3C4
- H3C6
- H3C7
- H3C8
- H3F2
- H3F3
- H3F3A
- H3F3B
- H3FA
- H3FB
- H3FC HIST1H3C
- H3FD
- H3FF
- H3FH
- H3FI
- H3FJ
- H3FK
- H3FL
- H3FM
- H3FT
- H4-16
- H4/A
- H4/B
- H4/C
- H4/D
- H4/E
- H4/G
- H4/H
- H4/I
- H4/J
- H4/K
- H4/M
- H4/N
- H4/O
- H4C1
- H4C11
- H4C12
- H4C13
- H4C14
- H4C15
- H4C16
- H4C2
- H4C3
- H4C4
- H4C5
- H4C6
- H4C8
- H4C9
- H4F2
- H4FA
- H4FB
- H4FC
- H4FD
- H4FE
- H4FG
- H4FH
- H4FI
- H4FJ
- H4FK
- H4FM
- H4FN
- H4FO
- HIRIP1
- HIRIP2
- HIST1H2AB
- HIST1H2AC
- HIST1H2AD
- HIST1H2AE
- HIST1H2AJ
- HIST1H2BA
- HIST1H2BB
- HIST1H2BC
- HIST1H2BD
- HIST1H2BE
- HIST1H2BF
- HIST1H2BG
- HIST1H2BH
- HIST1H2BI
- HIST1H2BJ
- HIST1H2BK
- HIST1H2BL
- HIST1H2BM
- HIST1H2BN
- HIST1H2BO
- HIST1H3A
- HIST1H3B
- HIST1H3D
- HIST1H3E
- HIST1H3F
- HIST1H3G
- HIST1H3H
- HIST1H3I
- HIST1H3J
- HIST1H4A
- HIST1H4B
- HIST1H4C
- HIST1H4D
- HIST1H4E
- HIST1H4F
- HIST1H4H
- HIST1H4I
- HIST1H4J
- HIST1H4K
- HIST1H4L
- HIST2H2AA
- HIST2H2AA3
- HIST2H2AA4
- HIST2H2AC
- HIST2H2BE
- HIST2H3A
- HIST2H3C
- HIST2H3D
- HIST2H4
- HIST2H4A
- HIST2H4B
- HIST3H2BB
- HIST3H3
- HIST4H4
- KIAA0056
- KMT5A
- LUZP5
- MCPH1
- NCAPD3
- NCAPG2
- NCAPH2
- P34CDC2
- PLK
- PLK1
- PRSET7
- RB1
- SET
- SET07
- SET8
- SETD8
- SMC2
- SMC2L1
- SMC4
- SMC4L1
- TSH2B
|
|
Regulation of HMOX1 expression and activity
|
|
|
- BACH1
- H13
- HM13
- HMOX1
- HO
- HO1
- IMP1
- MAFK
- NFE2L2
- NRF2
- PSL3
- SPP
|
|
Intraflagellar transport
|
|
|
- BITH
- C11orf2
- C11orf60
- C14orf179
- C1orf41
- C20orf9
- CCDC2
- CDV1
- CEV14
- CLUAP1
- CMG1
- D2LIC
- DERP8
- DHC1B
- DHC2
- DLC1
- DLC2
- DNCH2
- DNCL1
- DNCL2A
- DNCL2B
- DNCLC1
- DNLC2A
- DNLC2B
- DYH1B
- DYNC2H1
- DYNC2I1
- DYNC2I2
- DYNC2LI1
- DYNLL1
- DYNLL2
- DYNLRB1
- DYNLRB2
- DYNLT2
- DYNLT2B
- DYNLT5
- ESRRBL1
- HDLC1
- HIPPI
- HSPB11
- IFT121
- IFT122
- IFT139
- IFT140
- IFT144
- IFT172
- IFT20
- IFT22
- IFT25
- IFT27
- IFT43
- IFT46
- IFT52
- IFT54
- IFT56
- IFT57
- IFT70A
- IFT70B
- IFT74
- IFT80
- IFT81
- IFT88
- KIAA0359
- KIAA0590
- KIAA0643
- KIAA1179
- KIAA1336
- KIAA1374
- KIAA1405
- KIAA1638
- KIAA1992
- KIAA1997
- KIF17
- KIF3
- KIF3A
- KIF3AP
- KIF3B
- KIF3C
- KIF3X
- KIFAP3
- KPNB2
- LIC3
- MIP1
- MIPT3
- NGD5
- RABL4
- RABL5
- RAYL
- ROBLD1
- ROBLD2
- SMAP
- SPG
- TCTE3
- TCTEX1D1
- TCTEX1D2
- TCTEX1D3
- TG737
- TNPO1
- TRAF3IP1
- TRIP11
- TRN
- TTC10
- TTC21B
- TTC26
- TTC30A
- TTC30B
- WDR10
- WDR140
- WDR19
- WDR34
- WDR35
- WDR56
- WDR60
- WDTC2
|
|
Regulation of MITF-M-dependent genes involved in DNA damage repair and senescence
|
|
|
|
|
snRNP Assembly
|
|
|
- AAAS
- ADRACALA
- C7orf14
- CAIN
- CAN
- CBP20
- CBP80
- CG1
- CLCI
- CLNS1A
- COD
- D3S1231E
- DDX20
- DP103
- FAM51A1
- GEMIN2
- GEMIN3
- GEMIN4
- GEMIN5
- GEMIN6
- GEMIN7
- GEMIN8
- HCA137
- HRMT1L5
- IBP72
- ICLN
- JBP1
- KIAA0023
- KIAA0095
- KIAA0169
- KIAA0197
- KIAA0225
- KIAA0618
- KIAA0791
- KIAA0906
- MEP50
- MP44
- MRNP41
- NCBP
- NCBP1
- NCBP2
- NCOA6IP
- NDC1
- NPAP60L
- NUP107
- NUP120
- NUP121
- NUP133
- NUP153
- NUP155
- NUP160
- NUP188
- NUP205
- NUP210
- NUP214
- NUP35
- NUP358
- NUP37
- NUP42
- NUP43
- NUP50
- NUP53
- NUP54
- NUP62
- NUP75
- NUP85
- NUP88
- NUP93
- NUPL2
- PBSCF
- PBSCG
- PCNT1
- PHAX
- PIMT
- POM121
- POM121A
- POM121C
- PRMT5
- RAE1
- RANBP2
- RNUT1
- RNUXA
- SEC13
- SEC13A
- SEC13L1
- SEC13R
- SIP1
- SKB1
- SMN
- SMN1
- SMN2
- SMNC
- SMNT
- SNRPB
- SNRPB1
- SNRPD1
- SNRPD2
- SNRPD3
- SNRPE
- SNRPF
- SNRPG
- SNUPN
- SPN1
- TGS1
- TMEM48
- TPR
- WD45
- WDR77
|
|
Ca activated K+ channels
|
|
|
- IK1
- IKCA1
- K3
- KCA4
- KCNMA
- KCNMA1
- KCNMB1
- KCNMB2
- KCNMB3
- KCNMB4
- KCNMBL
- KCNN1
- KCNN2
- KCNN3
- KCNN4
- SK
- SK4
- SLO
|
|
Erythrocytes take up oxygen and release carbon dioxide
|
|
|
- AE1
- AQP1
- CA1
- CA2
- CA4
- CHIP28
- DI
- EPB3
- HBA1
- HBA2
- HBB
- RH50
- RHAG
- SLC4A1
|
|
SHOC2 M1731 mutant abolishes MRAS complex function
|
|
|
- ARAF
- ARAF1
- BRAF
- BRAF1
- KIAA0862
- MRAS
- PKS
- PKS2
- PPP1CB
- PPP1CC
- RAF
- RAF1
- RAFB1
- RRAS3
- SHOC2
- YWHAB
|
|
Negative regulation of FGFR3 signaling
|
|
|
- CBL
- CBL2
- ERK1
- ERK2
- FGF1
- FGF16
- FGF18
- FGF2
- FGF20
- FGF23
- FGF4
- FGF9
- FGFA
- FGFB
- FRS2
- HST
- HSTF1
- HYPF
- KS3
- MAPK1
- MAPK3
- PRKM1
- PRKM2
- PRKM3
- PTP2C
- PTPN11
- RNF55
- RPS27A
- SHPTP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
|
|
Class B/2 (Secretin family receptors)
|
|
|
- ADGRE1
- ADGRE2
- ADGRE3
- ADGRE5
- C2orf31
- CD55
- CD97
- CR
- CRFBP
- CRFR
- CRFR1
- CRH
- CRHBP
- CRHR
- CRHR1
- DAF
- DHH
- EMR1
- EMR2
- EMR3
- FZD1
- FZD10
- FZD2
- FZD3
- FZD4
- FZD5
- FZD6
- FZD7
- FZD8
- FZD9
- IHH
- INT1
- INT1L1
- INT4
- IRP
- PTCH
- PTCH1
- PTCH2
- PTH
- PTH1R
- PTH2
- PTH2R
- PTHLH
- PTHR
- PTHR1
- PTHR2
- PTHRP
- SHH
- SMO
- SMOH
- SPC
- SRP
- TIP39
- TIPF39
- TM7LN3
- UCN
- UCN2
- UCN3
- URP
- WNT1
- WNT10A
- WNT10B
- WNT11
- WNT12
- WNT13
- WNT14
- WNT14B
- WNT15
- WNT16
- WNT2
- WNT2B
- WNT3
- WNT3A
- WNT4
- WNT5A
- WNT6
- WNT7A
- WNT7B
- WNT8A
- WNT8B
- WNT8D
- WNT9A
- WNT9B
|
|
Maturation of nucleoprotein
|
|
|
- ADPRTL1
- ARTD15
- BAL
- BAL1
- BAL2
- C15orf30
- GSK3A
- GSK3B
- KIAA0177
- KIAA1268
- N
- PARP10
- PARP14
- PARP16
- PARP4
- PARP6
- PARP8
- PARP9
- PARPL
- SMT3C
- SMT3H3
- SUMO1
- UBC9
- UBCE9
- UBE2I
- UBL1
|
|
t(4;14) translocations of FGFR3
|
|
|
|
|
Translation of Structural Proteins
|
|
|
|
|
Biosynthesis of maresins
|
|
|
|
|
Defective F8 cleavage by thrombin
|
|
|
|
|
Voltage gated Potassium channels
|
|
|
- C1orf30
- EAG
- EAG1
- EAG2
- ERG
- ERG1
- ERG2
- ERG3
- HERG
- HGK5
- KCNA1
- KCNA10
- KCNA1B
- KCNA2
- KCNA2B
- KCNA3
- KCNA3B
- KCNA4
- KCNA4L
- KCNA5
- KCNA6
- KCNA7
- KCNA8
- KCNA9
- KCNAB1
- KCNAB2
- KCNAB3
- KCNB1
- KCNB2
- KCNC1
- KCNC2
- KCNC3
- KCNC4
- KCND1
- KCND2
- KCND3
- KCNF1
- KCNF2
- KCNG1
- KCNG2
- KCNG3
- KCNG4
- KCNH1
- KCNH2
- KCNH3
- KCNH4
- KCNH5
- KCNH6
- KCNH7
- KCNH8
- KCNK2
- KCNQ1
- KCNQ2
- KCNQ3
- KCNQ4
- KCNQ5
- KCNS1
- KCNS2
- KCNS3
- KCNV1
- KCNV2
- KIAA1044
- KIAA1144
- KIAA1282
- KVLQT1
|
|
Negative regulation of MAPK pathway
|
|
|
- ARAF
- ARAF1
- BRAF
- BRAF1
- BRAP
- C11orf81
- CL100
- CTAK1
- DUSP1
- DUSP10
- DUSP16
- DUSP2
- DUSP4
- DUSP5
- DUSP6
- DUSP7
- DUSP8
- DUSP9
- EMK2
- ERK1
- ERK2
- ERK6
- HRAS
- HRAS1
- KIAA0044
- KIAA1700
- KSR
- KSR1
- MAPK1
- MAPK12
- MAPK3
- MARK3
- MKP1
- MKP2
- MKP3
- MKP4
- MKP5
- MKP7
- NRAS
- PAC1
- PAQR3
- PBP
- PEBP
- PEBP1
- PKS
- PKS2
- PPP2CA
- PPP2CB
- PPP2R1A
- PPP2R1B
- PPP2R5A
- PPP2R5B
- PPP2R5C
- PPP2R5D
- PPP2R5E
- PPP5
- PPP5C
- PRKM1
- PRKM2
- PRKM3
- PTPH1
- PTPN10
- PTPN3
- PTPN7
- PYST1
- PYST2
- RAF
- RAF1
- RAFB1
- RNF52
- RPS27A
- SAPK3
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- VH1
- VH2
- VH3
- VH5
- YWHAB
|
|
Serotonin Neurotransmitter Release Cycle
|
|
|
- BZRAP1
- CPLX1
- KIAA0340
- KIAA0612
- KIAA0654
- KIAA0897
- LIP1
- PPFIA1
- PPFIA2
- PPFIA3
- PPFIA4
- RAB3A
- RAB3IP2
- RBP1
- RIM1
- RIMBP1
- RIMS1
- SLC18A2
- SNAP
- SNAP25
- STX1
- STX1A
- SVMT
- SVP65
- SYB2
- SYN1
- SYN2
- SYN3
- SYT
- SYT1
- TSPOAP1
- UNC13
- UNC13B
- VAMP2
- VMAT2
|
|
Free fatty acid receptors
|
|
|
- FFA2
- FFAR1
- FFAR2
- FFAR3
- FFAR4
- GPCR43
- GPR120
- GPR129
- GPR31
- GPR40
- GPR41
- GPR43
- O3FAR1
- PGR4
|
|
Defective GFPT1 causes CMSTA1
|
|
|
|
|
Interleukin-17 signaling
|
|
|
- 8
- CRL4
- CTLA8
- EVI27
- IL17
- IL17A
- IL17BR
- IL17C
- IL17E
- IL17F
- IL17R
- IL17RA
- IL17RB
- IL17RC
- IL17RE
- IL25
|
|
Defective SFTPA2 causes IPF
|
|
|
- COLEC5
- PSAP
- SFTP1
- SFTPA
- SFTPA2
- SFTPA2B
|
|