GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **1451 - 1475** of **2090** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol
Ras activation upon Ca2+ influx through NMDA receptor	Alpha-actinin-2 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Disks large homolog 1 Disks large homolog 2 Disks large homolog 3 Disks large homolog 4 GTPase HRas GTPase NRas Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2B Glutamate receptor ionotropic, NMDA 2D Leucine-rich repeat-containing protein 7 Neurofilament light polypeptide Ras-specific guanine nucleotide-releasing factor 1 Ras-specific guanine nucleotide-releasing factor 2	O14827 O15399 P01111 P01112 P07196 P0DP23 P35609 P78352 Q05586 Q12959 Q13224 Q13554 Q13555 Q13557 Q13972 Q15700 Q92796 Q96NW7 Q9UQM7	ACTN2 CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CDC25 DLG1 DLG2 DLG3 DLG4 GNRP GRF1 GRF2 GRIN1 GRIN2B GRIN2D GluN2D HRAS HRAS1 KIAA0968 KIAA1232 KIAA1365 LAP1 LRRC7 NEFL NF68 NFL NMDAR1 NMDAR2B NMDAR2D NRAS PSD95 RASGRF1 RASGRF2
GABA synthesis, release, reuptake and degradation	Complexin-1 DnaJ homolog subfamily C member 5 Glutamate decarboxylase 1 Glutamate decarboxylase 2 Heat shock cognate 71 kDa protein Ras-related protein Rab-3A Regulating synaptic membrane exocytosis protein 1 Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Vesicle-associated membrane protein 2 Vesicular inhibitory amino acid transporter	O14810 P11142 P20336 P21579 P60880 P63027 Q05329 Q16623 Q86UR5 Q99259 Q9H3Z4 Q9H598	CLN4 CPLX1 DNAJC5 GAD GAD1 GAD2 GAD65 GAD67 HSC70 HSP73 HSPA10 HSPA8 KIAA0340 RAB3A RAB3IP2 RIM1 RIMS1 SLC32A1 SNAP SNAP25 STX1 STX1A SVP65 SYB2 SYT SYT1 VAMP2 VGAT VIAAT
SHOC2 M1731 mutant abolishes MRAS complex function	14-3-3 protein beta/alpha Leucine-rich repeat protein SHOC-2 RAF proto-oncogene serine/threonine-protein kinase Ras-related protein M-Ras Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Serine/threonine-protein phosphatase PP1-beta catalytic subunit Serine/threonine-protein phosphatase PP1-gamma catalytic subunit	O14807 P04049 P10398 P15056 P31946 P36873 P62140 Q9UQ13	ARAF ARAF1 BRAF BRAF1 KIAA0862 MRAS PKS PKS2 PPP1CB PPP1CC RAF RAF1 RAFB1 RRAS3 SHOC2 YWHAB
Gain-of-function MRAS complexes activate RAF signaling	14-3-3 protein beta/alpha Leucine-rich repeat protein SHOC-2 RAF proto-oncogene serine/threonine-protein kinase Ras-related protein M-Ras Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Serine/threonine-protein phosphatase PP1-beta catalytic subunit Serine/threonine-protein phosphatase PP1-gamma catalytic subunit	O14807 P04049 P10398 P15056 P31946 P36873 P62140 Q9UQ13	ARAF ARAF1 BRAF BRAF1 KIAA0862 MRAS PKS PKS2 PPP1CB PPP1CC RAF RAF1 RAFB1 RRAS3 SHOC2 YWHAB
RAF activation	14-3-3 protein beta/alpha BRCA1-associated protein Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 GTPase HRas GTPase NRas Kinase suppressor of Ras 1 Leucine-rich repeat protein SHOC-2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase kinase kinase 11 Prohibitin 1 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ras-related protein M-Ras Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase PP1-beta catalytic subunit Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Tyrosine-protein kinase JAK2	O14807 O60674 P01111 P01112 P04049 P0DP23 P10398 P12931 P15056 P27448 P30153 P30154 P31946 P35232 P36507 P36873 P62140 P62714 P67775 Q02750 Q13362 Q13554 Q13555 Q13557 Q14738 Q15172 Q15173 Q16537 Q16584 Q7Z569 Q8IVT5 Q9UQ13 Q9UQM7	ARAF ARAF1 BRAF BRAF1 BRAP CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CTAK1 EMK2 HRAS HRAS1 JAK2 KIAA0044 KIAA0862 KIAA0968 KSR KSR1 MAP2K1 MAP2K2 MAP3K11 MARK3 MEK1 MEK2 MKK2 MLK3 MRAS NRAS PHB PHB1 PKS PKS2 PPP1CB PPP1CC PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PRKMK1 PRKMK2 PTK1 RAF RAF1 RAFB1 RNF52 RRAS3 SHOC2 SPRK SRC SRC1 YWHAB
Amine ligand-binding receptors	G-protein coupled receptor 143 Putative trace amine-associated receptor 3 Trace amine-associated receptor 1 Trace amine-associated receptor 2 Trace amine-associated receptor 5 Trace amine-associated receptor 6 Trace amine-associated receptor 8 Trace amine-associated receptor 9	O14804 P51810 Q969N4 Q96RI8 Q96RI9 Q96RJ0 Q9P1P4 Q9P1P5	GPR102 GPR143 GPR57 GPR58 OA1 PNR TA1 TA3 TA4 TA5 TAAR1 TAAR2 TAAR3 TAAR3P TAAR5 TAAR6 TAAR8 TAAR9 TAR1 TAR3 TAR4 TAR5 TRAR1 TRAR3 TRAR4 TRAR5
RNA Polymerase III Chain Elongation	DNA-directed RNA polymerase III subunit RPC10 DNA-directed RNA polymerase III subunit RPC1 DNA-directed RNA polymerase III subunit RPC2 DNA-directed RNA polymerase III subunit RPC3 DNA-directed RNA polymerase III subunit RPC4 DNA-directed RNA polymerase III subunit RPC5 DNA-directed RNA polymerase III subunit RPC6 DNA-directed RNA polymerase III subunit RPC7-like DNA-directed RNA polymerase III subunit RPC7 DNA-directed RNA polymerase III subunit RPC8 DNA-directed RNA polymerase III subunit RPC9 DNA-directed RNA polymerases I and III subunit RPAC1 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Protein POLR1D, isoform 2	O14802 O15160 O15318 O75575 P05423 P0DPB5 P19388 P52434 P53803 P61218 P62875 Q9BT43 Q9BUI4 Q9H1D9 Q9NVU0 Q9NW08 Q9Y2Y1 Q9Y535	BN51 BN51T CRCP KIAA1452 KIAA1665 POLR1C POLR1D POLR1E POLR2E POLR2F POLR2H POLR2K POLR2L POLR3A POLR3B POLR3C POLR3D POLR3E POLR3F POLR3G POLR3GL POLR3H POLR3K POLRF RPC11 RPC8
Cytosolic sensors of pathogen-associated DNA	DNA-dependent protein kinase catalytic subunit DNA-directed RNA polymerase III subunit RPC10 DNA-directed RNA polymerase III subunit RPC1 DNA-directed RNA polymerase III subunit RPC2 DNA-directed RNA polymerase III subunit RPC3 DNA-directed RNA polymerase III subunit RPC4 DNA-directed RNA polymerase III subunit RPC5 DNA-directed RNA polymerase III subunit RPC6 DNA-directed RNA polymerase III subunit RPC7-like DNA-directed RNA polymerase III subunit RPC7 DNA-directed RNA polymerase III subunit RPC8 DNA-directed RNA polymerase III subunit RPC9 DNA-directed RNA polymerases I and III subunit RPAC1 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Double-strand break repair protein MRE11 Interferon-inducible protein AIM2 Protein POLR1D, isoform 2 X-ray repair cross-complementing protein 5 X-ray repair cross-complementing protein 6	O14802 O14862 O15160 O15318 O75575 P05423 P0DPB5 P12956 P13010 P19388 P49959 P52434 P53803 P61218 P62875 P78527 Q9BT43 Q9BUI4 Q9H1D9 Q9NVU0 Q9NW08 Q9Y2Y1 Q9Y535	AIM2 BN51 BN51T CRCP G22P1 G22P2 HNGS1 HYRC HYRC1 KIAA1452 KIAA1665 MRE11 MRE11A POLR1C POLR1D POLR1E POLR2E POLR2F POLR2H POLR2K POLR2L POLR3A POLR3B POLR3C POLR3D POLR3E POLR3F POLR3G POLR3GL POLR3H POLR3K POLRF PRKDC RPC11 RPC8 XRCC5 XRCC6
Acetylcholine Neurotransmitter Release Cycle	Choline O-acetyltransferase Complexin-1 High affinity choline transporter 1 Liprin-alpha-1 Liprin-alpha-2 Liprin-alpha-3 Liprin-alpha-4 Peripheral-type benzodiazepine receptor-associated protein 1 Protein unc-13 homolog B Ras-related protein Rab-3A Regulating synaptic membrane exocytosis protein 1 Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Vesicle-associated membrane protein 2 Vesicular acetylcholine transporter	O14795 O14810 O75145 O75334 O75335 O95153 P20336 P21579 P28329 P60880 P63027 Q13136 Q16572 Q16623 Q86UR5 Q9GZV3	BZRAP1 CHAT CHT1 CPLX1 KIAA0340 KIAA0612 KIAA0654 KIAA0897 LIP1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 RAB3A RAB3IP2 RBP1 RIM1 RIMBP1 RIMS1 SLC18A3 SLC5A7 SNAP SNAP25 STX1 STX1A SVP65 SYB2 SYT SYT1 TSPOAP1 UNC13 UNC13B VACHT VAMP2
Norepinephrine Neurotransmitter Release Cycle	Amine oxidase [flavin-containing] A Complexin-1 Liprin-alpha-1 Liprin-alpha-2 Liprin-alpha-3 Liprin-alpha-4 Peripheral-type benzodiazepine receptor-associated protein 1 Protein unc-13 homolog B Ras-related protein Rab-3A Regulating synaptic membrane exocytosis protein 1 Solute carrier family 22 member 1 Solute carrier family 22 member 2 Synaptic vesicular amine transporter Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Vesicle-associated membrane protein 2	O14795 O14810 O15244 O15245 O75145 O75334 O75335 O95153 P20336 P21397 P21579 P60880 P63027 Q05940 Q13136 Q16623 Q86UR5	BZRAP1 CPLX1 KIAA0340 KIAA0612 KIAA0654 KIAA0897 LIP1 MAOA OCT1 OCT2 PPFIA1 PPFIA2 PPFIA3 PPFIA4 RAB3A RAB3IP2 RBP1 RIM1 RIMBP1 RIMS1 SLC18A2 SLC22A1 SLC22A2 SNAP SNAP25 STX1 STX1A SVMT SVP65 SYB2 SYT SYT1 TSPOAP1 UNC13 UNC13B VAMP2 VMAT2
Serotonin Neurotransmitter Release Cycle	Complexin-1 Liprin-alpha-1 Liprin-alpha-2 Liprin-alpha-3 Liprin-alpha-4 Peripheral-type benzodiazepine receptor-associated protein 1 Protein unc-13 homolog B Ras-related protein Rab-3A Regulating synaptic membrane exocytosis protein 1 Synapsin-1 Synapsin-2 Synapsin-3 Synaptic vesicular amine transporter Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Vesicle-associated membrane protein 2	O14795 O14810 O14994 O75145 O75334 O75335 O95153 P17600 P20336 P21579 P60880 P63027 Q05940 Q13136 Q16623 Q86UR5 Q92777	BZRAP1 CPLX1 KIAA0340 KIAA0612 KIAA0654 KIAA0897 LIP1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 RAB3A RAB3IP2 RBP1 RIM1 RIMBP1 RIMS1 SLC18A2 SNAP SNAP25 STX1 STX1A SVMT SVP65 SYB2 SYN1 SYN2 SYN3 SYT SYT1 TSPOAP1 UNC13 UNC13B VAMP2 VMAT2
Dopamine Neurotransmitter Release Cycle	Amyloid-beta A4 precursor protein-binding family A member 1 Complexin-1 Liprin-alpha-1 Liprin-alpha-2 Liprin-alpha-3 Liprin-alpha-4 Peripheral plasma membrane protein CASK Peripheral-type benzodiazepine receptor-associated protein 1 Protein lin-7 homolog A Protein lin-7 homolog B Protein lin-7 homolog C Protein unc-13 homolog B Ras-related protein Rab-3A Regulating synaptic membrane exocytosis protein 1 Synapsin-1 Synapsin-2 Synapsin-3 Synaptic vesicular amine transporter Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Vesicle-associated membrane protein 2	O14795 O14810 O14910 O14936 O14994 O75145 O75334 O75335 O95153 P17600 P20336 P21579 P60880 P63027 Q02410 Q05940 Q13136 Q16623 Q86UR5 Q92777 Q9HAP6 Q9NUP9	APBA1 BZRAP1 CASK CPLX1 KIAA0340 KIAA0612 KIAA0654 KIAA0897 LIN2 LIN7A LIN7B LIN7C LIP1 MALS1 MALS2 MALS3 MINT1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 RAB3A RAB3IP2 RBP1 RIM1 RIMBP1 RIMS1 SLC18A2 SNAP SNAP25 STX1 STX1A SVMT SVP65 SYB2 SYN1 SYN2 SYN3 SYT SYT1 TSPOAP1 UNC13 UNC13B VAMP2 VELI1 VELI2 VELI3 VMAT2 X11
FOXO-mediated transcription of cell cycle genes	Caveolin-1 Cyclin-G2 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B Forkhead box protein G1 Forkhead box protein O1 Forkhead box protein O3 Forkhead box protein O4 Growth arrest and DNA damage-inducible protein GADD45 alpha Growth/differentiation factor 8 Krueppel-like factor 4 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Poly(rC)-binding protein 4 Protein BTG1 Retinoblastoma-like protein 2	O14793 O43474 O43524 P24522 P38936 P46527 P55316 P57723 P62324 P84022 P98177 Q03135 Q08999 Q12778 Q13485 Q15796 Q16589	AFX AFX1 BTG1 CAP20 CAV CAV1 CCNG2 CDKN1 CDKN1A CDKN1B CIP1 DDIT1 DPC4 EZF FKH2 FKHL1 FKHL2 FKHL3 FKHL4 FKHR FKHRL1 FOXG1 FOXG1A FOXG1B FOXG1C FOXO1 FOXO1A FOXO3 FOXO3A FOXO4 GADD45 GADD45A GDF8 GKLF KIP1 KLF4 MADH2 MADH3 MADH4 MADR2 MDA6 MLLT7 MSTN PCBP4 PIC1 RB2 RBL2 SDI1 SMAD2 SMAD3 SMAD4 WAF1 p27
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 CD40 ligand Lymphotoxin-alpha Lymphotoxin-beta Mitogen-activated protein kinase kinase kinase 14 TNF receptor-associated factor 2 TNF receptor-associated factor 3 Tumor necrosis factor ligand superfamily member 11 Tumor necrosis factor ligand superfamily member 12 Tumor necrosis factor ligand superfamily member 13B Tumor necrosis factor ligand superfamily member 14 Tumor necrosis factor receptor superfamily member 11A Tumor necrosis factor receptor superfamily member 12A Tumor necrosis factor receptor superfamily member 13C Tumor necrosis factor receptor superfamily member 3	O14788 O43508 O43557 P01374 P29965 P36941 Q06643 Q12933 Q13114 Q13489 Q13490 Q96RJ3 Q99558 Q9NP84 Q9Y275 Q9Y6Q6	API1 API2 APO3L BAFF BAFFR BIRC2 BIRC3 BLYS BR3 CAP-1 CD40L CD40LG CRAF1 D12S370 DR3LG FN14 HVEML LIGHT LTA LTB LTBR MAP3K14 MIHB MIHC NIK OPGL RANK RANKL RNF48 RNF49 TALL1 TNFB TNFC TNFCR TNFR3 TNFRSF11A TNFRSF12A TNFRSF13C TNFRSF3 TNFSF1 TNFSF11 TNFSF12 TNFSF13B TNFSF14 TNFSF20 TNFSF3 TNFSF5 TRAF2 TRAF3 TRAFAMN TRANCE TRAP TRAP3 ZTNF4
Signal transduction by L1	Casein kinase II subunit alpha' Casein kinase II subunit alpha Casein kinase II subunit beta Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Epidermal growth factor receptor Guanine nucleotide exchange factor VAV2 Integrin alpha-5 Integrin alpha-9 Integrin alpha-IIb Integrin alpha-V Integrin beta-1 Integrin beta-3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Neural cell adhesion molecule 1 Neural cell adhesion molecule L1 Neuropilin-1 Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 1	O14786 P00533 P05106 P05556 P06756 P08514 P08648 P13591 P19784 P27361 P28482 P32004 P36507 P52735 P63000 P67870 P68400 Q02750 Q13153 Q13797	CAML1 CK2A1 CK2A2 CK2N CSNK2A1 CSNK2A2 CSNK2B EGFR ERBB ERBB1 ERK1 ERK2 FNRA FNRB G5A GP2B GP3A HER1 ITGA2B ITGA5 ITGA9 ITGAB ITGAV ITGB1 ITGB3 L1CAM MAP2K1 MAP2K2 MAPK1 MAPK3 MDF2 MEK1 MEK2 MIC5 MKK2 MSK12 MSK8 NCAM NCAM1 NRP NRP1 PAK1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 RAC1 TC25 VAV2 VEGF165R VNRA VTNR
Signaling by ROBO receptors	C-X-C chemokine receptor type 4 Ena/VASP-like protein Glypican-1 Leucine-rich repeat transmembrane protein FLRT3 Neuropilin-1 Profilin-1 Profilin-2 Protein enabled homolog Roundabout homolog 1 Roundabout homolog 2 Slit homolog 1 protein Slit homolog 2 protein Slit homolog 3 protein Stromal cell-derived factor 1 Vasodilator-stimulated phosphoprotein	O14786 O75093 O75094 O94813 P07737 P35052 P35080 P48061 P50552 P61073 Q8N8S7 Q9HCK4 Q9NZU0 Q9UI08 Q9Y6N7	CXCL12 CXCR4 DUTT1 ENAH EVL FLRT3 GPC1 KIAA0813 KIAA0814 KIAA1469 KIAA1568 MEGF4 MEGF5 MENA NRP NRP1 PFN1 PFN2 RNB6 ROBO1 ROBO2 SDF1 SDF1A SDF1B SLIL1 SLIL2 SLIL3 SLIT1 SLIT2 SLIT3 VASP VEGF165R
Sema3A PAK dependent Axon repulsion	Cofilin-1 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta LIM domain kinase 1 Neuropilin-1 Plexin-A1 Plexin-A2 Plexin-A3 Plexin-A4 Ras-related C3 botulinum toxin substrate 1 Semaphorin-3A Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Tyrosine-protein kinase Fes/Fps Tyrosine-protein kinase Fyn	O14786 O75051 O75914 P06241 P07332 P07900 P08238 P23528 P51805 P53667 P63000 Q13153 Q13177 Q14563 Q9HCM2 Q9UIW2	CFL CFL1 FES FPS FYN HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB KIAA0463 KIAA1550 LIMK LIMK1 NOV NRP NRP1 OCT OPHN3 PAK1 PAK2 PAK3 PLXN1 PLXN2 PLXN4 PLXNA1 PLXNA2 PLXNA3 PLXNA4 PLXNA4A PLXNA4B RAC1 SEMA3A SEMAD SEX TC25 VEGF165R
Neurophilin interactions with VEGF and VEGFR	Neuropilin-1 Neuropilin-2 Vascular endothelial growth factor receptor 1 Vascular endothelial growth factor receptor 2	O14786 O60462 P17948 P35968	FLK1 FLT FLT1 FRT KDR NRP NRP1 NRP2 VEGF165R VEGF165R2 VEGFR1 VEGFR2
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	FERM, ARHGEF and pleckstrin domain-containing protein 2 Neuropilin-1 Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma Plexin-A1 Plexin-A2 Plexin-A3 Plexin-A4 Ras-related C3 botulinum toxin substrate 1 Ras-related protein R-Ras Rho-related GTP-binding protein Rho6 Semaphorin-3A Talin-1 Tyrosine-protein kinase Fes/Fps Tyrosine-protein kinase Fyn	O14786 O60331 O75051 O94887 P06241 P07332 P10301 P51805 P63000 Q14563 Q92730 Q9HCM2 Q9UIW2 Q9Y490	FARP2 FES FPS FYN KIAA0463 KIAA0589 KIAA0793 KIAA1027 KIAA1550 NOV NRP NRP1 OCT PIP5K1C PLEKHC3 PLXN1 PLXN2 PLXN4 PLXNA1 PLXNA2 PLXNA3 PLXNA4 PLXNA4A PLXNA4B RAC1 RHO6 RND1 RRAS SEMA3A SEMAD SEX TC25 TLN TLN1 VEGF165R
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex	14-3-3 protein beta/alpha 14-3-3 protein epsilon 14-3-3 protein eta 14-3-3 protein gamma 14-3-3 protein sigma 14-3-3 protein theta 14-3-3 protein zeta/delta Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 M-phase inducer phosphatase 3 Serine/threonine-protein kinase Chk1 Serine/threonine-protein kinase Chk2 Wee1-like protein kinase	O14757 O96017 P06493 P14635 P27348 P30291 P30307 P31946 P31947 P61981 P62258 P63104 Q04917	CCNB CCNB1 CDC2 CDC25C CDC28A CDK1 CDKN1 CDS1 CHEK1 CHEK2 CHK1 CHK2 HME1 P34CDC2 RAD53 SFN WEE1 YWHA1 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ
Processing of DNA double-strand break ends	ATR-interacting protein BRCA1-A complex subunit Abraxas 1 BRCA1-A complex subunit RAP80 BRCA1-associated RING domain protein 1 BRISC and BRCA1-A complex member 1 BRISC and BRCA1-A complex member 2 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Cell cycle checkpoint control protein RAD9A Cell cycle checkpoint control protein RAD9B Cell cycle checkpoint protein RAD17 Cell cycle checkpoint protein RAD1 Checkpoint protein HUS1 Claspin Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 DNA endonuclease RBBP8 DNA repair protein RAD50 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 2-binding protein 1 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 E3 SUMO-protein ligase PIAS4 E3 ubiquitin-protein ligase HERC2 E3 ubiquitin-protein ligase RNF168 E3 ubiquitin-protein ligase RNF4 E3 ubiquitin-protein ligase RNF8 Exonuclease 1 Fanconi anemia group J protein Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1t Histone H4 Histone acetyltransferase KAT5 Histone-lysine N-methyltransferase NSD2 Lys-63-specific deubiquitinase BRCC36 Mediator of DNA damage checkpoint protein 1 NAD-dependent protein deacylase sirtuin-6 Nibrin Polyubiquitin-B Polyubiquitin-C Protein timeless homolog RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit SUMO-conjugating enzyme UBC9 Serine-protein kinase ATM Serine/threonine-protein kinase ATR Serine/threonine-protein kinase Chk1 Serine/threonine-protein phosphatase 4 catalytic subunit Serine/threonine-protein phosphatase 4 regulatory subunit 2 Small ubiquitin-related modifier 2 TIMELESS-interacting protein TP53-binding protein 1 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14757 O60671 O60814 O60921 O60934 O75943 O76064 O95714 O96028 P06899 P0CG47 P0CG48 P15927 P16104 P20248 P23527 P24941 P27694 P33778 P35244 P35249 P35250 P38398 P40937 P40938 P46736 P49959 P51530 P54132 P57053 P58876 P60510 P61088 P61956 P62805 P62807 P62979 P62987 P63279 P78317 P78396 Q12888 Q13315 Q13472 Q13535 Q14191 Q14676 Q15819 Q16695 Q16778 Q6UWZ7 Q6WBX8 Q8IYW5 Q8N257 Q8N2W9 Q8N6T7 Q8WXE1 Q92547 Q92878 Q92993 Q93079 Q96A08 Q96E14 Q96RL1 Q99638 Q99708 Q99728 Q99877 Q99879 Q99880 Q9BSD3 Q9BVW5 Q9BX63 Q9H9A7 Q9HAW4 Q9NWV8 Q9NXR7 Q9NY27 Q9UNS1 Q9UQ84	ABRA1 ABRAXAS1 AGS1 ATM ATR ATRIP BABAM1 BABAM2 BACH1 BARD1 BLM BLU BRCA1 BRCC3 BRCC36 BRCC45 BRE BRIP1 C12orf32 C16orf75 C19orf62 C6.1A C9orf76 CCDC98 CCN1 CCNA CCNA1 CCNA2 CDK2 CDKN2 CHEK1 CHK1 CLSPN CTIP CXorf53 DNA2 DNA2L EXO1 EXOI FAM175A FANCJ FRP1 H2AFX H2AX H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-4 H3FT H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HERC2 HEX1 HIRIP1 HIRIP2 HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2BE HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST3H3 HIST4H4 HNGS1 HTATIP HUS1 KAT5 KIAA0083 KIAA0170 KIAA0259 KIAA0646 KIAA1090 MDC1 MERIT40 MMS2 MMSET MRE11 MRE11A NBA1 NBN NBS NBS1 NFBD1 NSD2 P95 PIAS4 PIASG PPP4 PPP4C PPP4R2 PPX R24L RAD1 RAD17 RAD50 RAD9A RAD9B RAP80 RBBP8 REC1 RECQ2 RECQ3 RECQL2 RECQL3 REPA1 REPA2 REPA3 RFC2 RFC3 RFC4 RFC5 RHINO RHNO1 RMI1 RMI2 RNF168 RNF4 RNF53 RNF8 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A RXRIP110 SIR2L6 SIRT6 SMT3B SMT3H2 SNURF SUMO2 TIM TIM1 TIMELESS TIMELESS1 TIP60 TIPIN TOP3 TOP3A TOPBP1 TP53BP1 TRX5 TSH2B UBA52 UBA80 UBB UBC UBC9 UBCE9 UBCEP1 UBCEP2 UBE2I UBE2N UBE2V2 UEV2 UIMC1 WHSC1 WRN
G2/M DNA damage checkpoint	ATR-interacting protein BRCA1-A complex subunit Abraxas 1 BRCA1-A complex subunit RAP80 BRCA1-associated RING domain protein 1 BRISC and BRCA1-A complex member 1 BRISC and BRCA1-A complex member 2 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Cell cycle checkpoint control protein RAD9A Cell cycle checkpoint control protein RAD9B Cell cycle checkpoint protein RAD17 Cell cycle checkpoint protein RAD1 Cellular tumor antigen p53 Checkpoint protein HUS1 DNA endonuclease RBBP8 DNA repair protein RAD50 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 2-binding protein 1 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 E3 SUMO-protein ligase PIAS4 E3 ubiquitin-protein ligase HERC2 E3 ubiquitin-protein ligase RNF168 E3 ubiquitin-protein ligase RNF8 Exonuclease 1 Fanconi anemia group J protein Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1t Histone H4 Histone acetyltransferase KAT5 Histone-lysine N-methyltransferase NSD2 Lys-63-specific deubiquitinase BRCC36 Mediator of DNA damage checkpoint protein 1 Nibrin RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Serine-protein kinase ATM Serine/threonine-protein kinase ATR Serine/threonine-protein kinase Chk1 Serine/threonine-protein kinase Chk2 TP53-binding protein 1 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 2	O14757 O60671 O60814 O60921 O60934 O75943 O76064 O95714 O96017 O96028 P04637 P06899 P15927 P16104 P23527 P27694 P33778 P35244 P35249 P35250 P38398 P40937 P40938 P46736 P49959 P51530 P54132 P57053 P58876 P61088 P62805 P62807 Q12888 Q13315 Q13472 Q13535 Q14191 Q14676 Q15819 Q16695 Q16778 Q6UWZ7 Q6WBX8 Q8IYW5 Q8N257 Q8N2W9 Q8WXE1 Q92547 Q92878 Q92993 Q93079 Q96A08 Q96E14 Q96RL1 Q99638 Q99708 Q99728 Q99877 Q99879 Q99880 Q9BSD3 Q9BX63 Q9H9A7 Q9NWV8 Q9NXR7 Q9UQ84	ABRA1 ABRAXAS1 AGS1 ATM ATR ATRIP BABAM1 BABAM2 BACH1 BARD1 BLM BLU BRCA1 BRCC3 BRCC36 BRCC45 BRE BRIP1 C12orf32 C16orf75 C19orf62 C6.1A C9orf76 CCDC98 CDS1 CHEK1 CHEK2 CHK1 CHK2 CTIP CXorf53 DNA2 DNA2L EXO1 EXOI FAM175A FANCJ FRP1 H2AFX H2AX H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-4 H3FT H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HERC2 HEX1 HIRIP1 HIRIP2 HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2BE HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST3H3 HIST4H4 HNGS1 HTATIP HUS1 KAT5 KIAA0083 KIAA0170 KIAA0259 KIAA0646 KIAA1090 MDC1 MERIT40 MMS2 MMSET MRE11 MRE11A NBA1 NBN NBS NBS1 NFBD1 NSD2 P53 P95 PIAS4 PIASG R24L RAD1 RAD17 RAD50 RAD53 RAD9A RAD9B RAP80 RBBP8 REC1 RECQ2 RECQ3 RECQL2 RECQL3 REPA1 REPA2 REPA3 RFC2 RFC3 RFC4 RFC5 RHINO RHNO1 RMI1 RMI2 RNF168 RNF53 RNF8 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RXRIP110 TIP60 TOP3 TOP3A TOPBP1 TP53 TP53BP1 TRX5 TSH2B UBE2N UBE2V2 UEV2 UIMC1 WHSC1 WRN
Presynaptic phase of homologous DNA pairing and strand exchange	26S proteasome complex subunit SEM1 ATR-interacting protein BRCA1-associated RING domain protein 1 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Breast cancer type 2 susceptibility protein Cell cycle checkpoint control protein RAD9A Cell cycle checkpoint control protein RAD9B Cell cycle checkpoint protein RAD17 Cell cycle checkpoint protein RAD1 Checkpoint protein HUS1 DNA endonuclease RBBP8 DNA repair protein RAD50 DNA repair protein RAD51 homolog 1 DNA repair protein RAD51 homolog 2 DNA repair protein RAD51 homolog 3 DNA repair protein RAD51 homolog 4 DNA repair protein XRCC2 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 2-binding protein 1 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 Exonuclease 1 Fanconi anemia group J protein Histone acetyltransferase KAT5 Nibrin RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Serine-protein kinase ATM Serine/threonine-protein kinase ATR Serine/threonine-protein kinase Chk1	O14757 O15315 O43502 O43543 O60671 O60921 O60934 O75771 O75943 P15927 P27694 P35244 P35249 P35250 P38398 P40937 P40938 P49959 P51530 P51587 P54132 P60896 Q06609 Q13315 Q13472 Q13535 Q14191 Q6WBX8 Q8WXE1 Q92547 Q92878 Q92993 Q96E14 Q99638 Q99708 Q99728 Q9BSD3 Q9BX63 Q9H9A7 Q9UQ84	AGS1 ATM ATR ATRIP BACH1 BARD1 BLM BRCA1 BRCA2 BRIP1 C12orf32 C16orf75 C7orf76 C9orf76 CHEK1 CHK1 CTIP DNA2 DNA2L DSS1 EXO1 EXOI FACD FANCD1 FANCJ FRP1 HEX1 HNGS1 HTATIP HUS1 KAT5 KIAA0083 KIAA0259 MRE11 MRE11A NBN NBS NBS1 P95 R24L RAD1 RAD17 RAD50 RAD51 RAD51A RAD51B RAD51C RAD51D RAD51L1 RAD51L2 RAD51L3 RAD9A RAD9B RBBP8 REC1 REC2 RECA RECQ2 RECQ3 RECQL2 RECQL3 REPA1 REPA2 REPA3 RFC2 RFC3 RFC4 RFC5 RHINO RHNO1 RMI1 RMI2 RNF53 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 SEM1 SHFDG1 SHFM1 TIP60 TOP3 TOP3A TOPBP1 WRN XRCC2
The canonical retinoid cycle in rods (twilight vision)	17-beta-hydroxysteroid dehydrogenase type 1 17-beta-hydroxysteroid dehydrogenase type 6 Cytochrome P450 4V2 Dehydrogenase/reductase SDR family member 9 Lecithin retinol acyltransferase Receptor for retinol uptake STRA6 Retinal-specific phospholipid-transporting ATPase ABCA4 Retinaldehyde-binding protein 1 Retinoid isomerohydrolase Retinol dehydrogenase 10 Retinol dehydrogenase 11 Retinol dehydrogenase 12 Retinol dehydrogenase 16 Retinol dehydrogenase 5 Retinol dehydrogenase 8 Retinol-binding protein 1 Retinol-binding protein 3 Retinol-binding protein 4 Rhodopsin Short-chain dehydrogenase/reductase family 9C member 7 Transthyretin Unconventional myosin-VIIa	O14756 O75452 O95237 P02753 P02766 P08100 P09455 P10745 P12271 P14061 P78363 Q13402 Q16518 Q6ZWL3 Q8IZV5 Q8NEX9 Q8TC12 Q92781 Q96NR8 Q9BPW9 Q9BX79 Q9NYR8	ABCA4 ABCR ARSDR1 CRALBP CRBP1 CYP4V2 DHRS9 E17KSR EDH17B1 EDH17B2 EDHB17 HSD17B1 HSD17B6 HSD17B9 LRAT MYO7A OPN2 PALB PRRDH PSDR1 RBP1 RBP3 RBP4 RDH1 RDH10 RDH11 RDH12 RDH15 RDH16 RDH5 RDH8 RDHS RHO RLBP1 RODH RODH4 RPE65 SDR16C4 SDR28C1 SDR28C2 SDR7C1 SDR7C2 SDR9C4 SDR9C5 SDR9C6 SDR9C7 SDR9C8 SDRO STRA6 TTR USH1B
Regulation of MITF-M-dependent genes involved in DNA damage repair and senescence	DNA ligase 1 Telomerase reverse transcriptase	O14746 P18858	EST2 LIG1 TCS1 TERT TRT

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