GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **426 - 450** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Beta-catenin phosphorylation cascade	APC membrane recruitment protein 1 Adenomatous polyposis coli protein Axin-1 Casein kinase I isoform alpha Catenin beta-1 GSK-3-binding protein FRAT2 Glycogen synthase kinase-3 beta Proto-oncogene FRAT1 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	O15169 O75474 P25054 P30153 P30154 P35222 P48729 P49841 P62714 P67775 Q13362 Q14738 Q15172 Q15173 Q16537 Q5JTC6 Q92837	AMER1 APC AXIN AXIN1 CSNK1A1 CTNNB CTNNB1 DP2.5 FAM123B FRAT1 FRAT2 GSK3B KIAA0044 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E WTX	Homo sapiens (human)
NRAGE signals death through JNK	A-kinase anchor protein 13 Active breakpoint cluster region-related protein Bcl-2-like protein 11 Bcl2-associated agonist of cell death Beta-nerve growth factor Ephexin-1 FYVE, RhoGEF and PH domain-containing protein 1 FYVE, RhoGEF and PH domain-containing protein 2 FYVE, RhoGEF and PH domain-containing protein 3 FYVE, RhoGEF and PH domain-containing protein 4 Guanine nucleotide exchange factor DBS Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Guanine nucleotide-binding protein subunit alpha-13 Intersectin-1 Kalirin Melanoma-associated antigen D1 Mitogen-activated protein kinase 8 Neuroepithelial cell-transforming gene 1 protein Obscurin Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Pleckstrin homology domain-containing family G member 2 Pleckstrin homology domain-containing family G member 5 Protein AATF Protein ECT2 Proto-oncogene DBL Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Ras-specific guanine nucleotide-releasing factor 2 Rho guanine nucleotide exchange factor 10-like protein Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 16 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 18 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 26 Rho guanine nucleotide exchange factor 2 Rho guanine nucleotide exchange factor 33 Rho guanine nucleotide exchange factor 35 Rho guanine nucleotide exchange factor 37 Rho guanine nucleotide exchange factor 38 Rho guanine nucleotide exchange factor 39 Rho guanine nucleotide exchange factor 3 Rho guanine nucleotide exchange factor 40 Rho guanine nucleotide exchange factor 4 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 6 Rho guanine nucleotide exchange factor 7 Rho guanine nucleotide exchange factor 9 Rho guanine nucleotide exchange factor TIAM1 Rho guanine nucleotide exchange factor TIAM2 Son of sevenless homolog 1 Son of sevenless homolog 2 Triple functional domain protein Tumor necrosis factor receptor superfamily member 16	A1IGU5 A5YM69 A8MVX0 O14827 O15013 O15068 O15085 O43307 O43521 O60229 O75962 O94827 O94989 P01138 P08138 P10911 P15498 P45983 P52735 P63000 P98174 Q07889 Q07890 Q12774 Q12802 Q12979 Q13009 Q14155 Q14344 Q15052 Q15811 Q5JSP0 Q5VST9 Q5VV41 Q6ZSZ5 Q7Z628 Q7Z6J4 Q8IVF5 Q8IW93 Q8N4T4 Q8N5V2 Q8TCU6 Q8TER5 Q92888 Q92934 Q92974 Q96DR7 Q96M96 Q96PE2 Q9H7P9 Q9H8V3 Q9HCE6 Q9NR80 Q9NR81 Q9NXL2 Q9NY61 Q9NZN5 Q9UKW4 Q9Y5V3	AATF ABR AKAP13 ARHDH9 ARHGEF1 ARHGEF10 ARHGEF10L ARHGEF11 ARHGEF12 ARHGEF15 ARHGEF16 ARHGEF17 ARHGEF18 ARHGEF19 ARHGEF2 ARHGEF26 ARHGEF3 ARHGEF33 ARHGEF35 ARHGEF37 ARHGEF38 ARHGEF39 ARHGEF4 ARHGEF40 ARHGEF5 ARHGEF5L ARHGEF6 ARHGEF7 ARHGEF8 ARHGEF9 BAD BBC6 BCL2L11 BCL2L8 BIM BRX C9orf100 CHE1 COOL1 COOL2 DBL DED DUET DUO ECT2 EPHEXIN4 FGD1 FGD2 FGD3 FGD4 FGDY FRABP GNA13 GRF2 GRINCHGEF HAPIP HT31 ITSN ITSN1 JNK1 KALRN KIAA0006 KIAA0142 KIAA0294 KIAA0337 KIAA0362 KIAA0380 KIAA0382 KIAA0424 KIAA0521 KIAA0651 KIAA0720 KIAA0915 KIAA1112 KIAA1415 KIAA1556 KIAA1626 KIAA1639 KIAA2016 LARG LBC LFP40 MAGED1 MAPK8 MCF2 MCF2L NBR NET1 NGEF NGF NGFB NGFR NRAGE OBSCN OST P85SPR PAK3BP PIXA PIXB PLEKHG2 PLEKHG5 PREX1 PRKM8 RAC1 RASGRF2 SAPK1 SAPK1C SGEF SH3D1A SOLO SOS1 SOS2 STEF TC25 TEM4 TIAM1 TIAM2 TIM TNFRSF16 TRAD TRIO VAV VAV1 VAV2 VAV3 ZFYVE3 ZFYVE4 ZFYVE5 ZFYVE6	Homo sapiens (human)
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)	26S proteasome complex subunit SEM1 BRCA1-associated RING domain protein 1 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Breast cancer type 2 susceptibility protein DNA endonuclease RBBP8 DNA repair protein RAD50 DNA repair protein RAD51 homolog 1 DNA repair protein RAD51 homolog 2 DNA repair protein RAD51 homolog 3 DNA repair protein RAD51 homolog 4 DNA repair protein XRCC2 DNA repair protein XRCC3 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 Exonuclease 1 Fanconi anemia group J protein Histone acetyltransferase KAT5 Nibrin Partner and localizer of BRCA2 RAD51-associated protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Regulator of telomere elongation helicase 1 Serine-protein kinase ATM	O15315 O43502 O43542 O43543 O60934 O75771 P38398 P49959 P51530 P51587 P54132 P60896 Q06609 Q13315 Q13472 Q14191 Q86YC2 Q92878 Q92993 Q96B01 Q96E14 Q99708 Q99728 Q9BX63 Q9H9A7 Q9NZ71 Q9UQ84	ATM BACH1 BARD1 BLM BRCA1 BRCA2 BRIP1 C16orf75 C20orf41 C7orf76 C9orf76 CTIP DNA2 DNA2L DSS1 EXO1 EXOI FACD FANCD1 FANCJ FANCN HEX1 HNGS1 HTATIP KAT5 KIAA0083 KIAA1088 MRE11 MRE11A NBN NBS NBS1 NHL P95 PALB2 PIR51 RAD50 RAD51 RAD51A RAD51AP1 RAD51B RAD51C RAD51D RAD51L1 RAD51L2 RAD51L3 RBBP8 REC2 RECA RECQ2 RECQ3 RECQL2 RECQL3 RMI1 RMI2 RNF53 RTEL1 SEM1 SHFDG1 SHFM1 TIP60 TOP3 TOP3A WRN XRCC2 XRCC3	Homo sapiens (human)
Deactivation of the beta-catenin transactivating complex	14-3-3 protein zeta/delta Adenomatous polyposis coli protein B-cell CLL/lymphoma 9 protein B-cell CLL/lymphoma 9-like protein Beta-catenin-interacting protein 1 C-terminal-binding protein 1 Catenin beta-1 Chromodomain-helicase-DNA-binding protein 8 E3 ubiquitin-protein ligase XIAP Exportin-1 F-box/WD repeat-containing protein 1A Histone deacetylase 1 Histone-lysine N-methyltransferase 2D Lymphoid enhancer-binding factor 1 Menin Polyubiquitin-B Polyubiquitin-C Protein chibby homolog 1 Pygopus homolog 1 Pygopus homolog 2 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase Retinoblastoma-binding protein 5 Set1/Ash2 histone methyltransferase complex subunit ASH2 Sex-determining region Y protein Transcription factor 7-like 1 Transcription factor 7-like 2 Transcription factor 7 Transcription factor SOX-13 Transcription factor SOX-17 Transcription factor SOX-2 Transcription factor SOX-3 Transcription factor SOX-4 Transcription factor SOX-6 Transcription factor SOX-7 Transcription factor SOX-9 Transducin-like enhancer protein 1 Transducin-like enhancer protein 2 Transducin-like enhancer protein 3 Transducin-like enhancer protein 4 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00255 O00512 O14686 O14980 P0CG47 P0CG48 P25054 P31749 P31751 P35222 P35712 P36402 P41225 P48431 P48436 P62979 P62987 P63104 P98170 Q04724 Q04725 Q04726 Q04727 Q05066 Q06945 Q13363 Q13547 Q15291 Q86UU0 Q9BRQ0 Q9BT81 Q9H6I2 Q9HCK8 Q9HCS4 Q9NQB0 Q9NSA3 Q9UBL3 Q9UJU2 Q9UN79 Q9Y297 Q9Y3M2 Q9Y3Y4	AKT1 AKT2 ALR APC API3 ARB1 ASH2L ASH2L1 BCL9 BCL9L BIRC4 BTRC BTRCP C22orf2 CBY CBY1 CHD8 CRM1 CTBP CTBP1 CTNNB CTNNB1 CTNNBIP1 DLNB11 DP2.5 FBW1A FBXW1A GRG4 HDAC1 HELSNF1 IAP3 ICAT KIAA1261 KIAA1547 KIAA1564 KMT2D LEF1 MEN1 MLL2 MLL4 PGEA1 PKB PYGO1 PYGO2 RAC RBBP5 RBQ3 RPD3L1 RPS27A SCG2 SOX13 SOX17 SOX2 SOX3 SOX4 SOX6 SOX7 SOX9 SRY TCF1 TCF3 TCF4 TCF7 TCF7L1 TCF7L2 TDF TLE1 TLE2 TLE3 TLE4 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 XIAP XPO1 YWHAZ	Homo sapiens (human)
Dopamine Neurotransmitter Release Cycle	Amyloid-beta A4 precursor protein-binding family A member 1 Complexin-1 Liprin-alpha-1 Liprin-alpha-2 Liprin-alpha-3 Liprin-alpha-4 Peripheral plasma membrane protein CASK Peripheral-type benzodiazepine receptor-associated protein 1 Protein lin-7 homolog A Protein lin-7 homolog B Protein lin-7 homolog C Protein unc-13 homolog B Ras-related protein Rab-3A Regulating synaptic membrane exocytosis protein 1 Synapsin-1 Synapsin-2 Synapsin-3 Synaptic vesicular amine transporter Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Vesicle-associated membrane protein 2	O14795 O14810 O14910 O14936 O14994 O75145 O75334 O75335 O95153 P17600 P20336 P21579 P60880 P63027 Q02410 Q05940 Q13136 Q16623 Q86UR5 Q92777 Q9HAP6 Q9NUP9	APBA1 BZRAP1 CASK CPLX1 KIAA0340 KIAA0612 KIAA0654 KIAA0897 LIN2 LIN7A LIN7B LIN7C LIP1 MALS1 MALS2 MALS3 MINT1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 RAB3A RAB3IP2 RBP1 RIM1 RIMBP1 RIMS1 SLC18A2 SNAP SNAP25 STX1 STX1A SVMT SVP65 SYB2 SYN1 SYN2 SYN3 SYT SYT1 TSPOAP1 UNC13 UNC13B VAMP2 VELI1 VELI2 VELI3 VMAT2 X11	Homo sapiens (human)
SMAC (DIABLO) binds to IAPs	Apoptotic protease-activating factor 1 Caspase-3 Caspase-7 Caspase-9 Cytochrome c Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP	O14727 P42574 P55210 P55211 P98170 P99999 Q9NR28	APAF1 API3 BIRC4 CASP3 CASP7 CASP9 CPP32 CYC CYCS DIABLO IAP3 KIAA0413 MCH3 MCH6 SMAC XIAP	Homo sapiens (human)
RORA activates gene expression	3'-5' exoribonuclease HELZ2 CREB-binding protein Carnitine O-palmitoyltransferase 1, liver isoform Chromodomain-helicase-DNA-binding protein 9 F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Histone acetyltransferase p300 Histone-arginine methyltransferase CARM1 Mediator of RNA polymerase II transcription subunit 1 Nuclear receptor ROR-alpha Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Nuclear receptor coactivator 6 Peroxisome proliferator-activated receptor alpha Retinoic acid receptor RXR-alpha SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 Sterol regulatory element-binding protein 1 Trimethylguanosine synthase	O60907 P19793 P35398 P36956 P50416 Q07869 Q09472 Q14686 Q15596 Q15648 Q15788 Q3L8U1 Q6STE5 Q86X55 Q92793 Q96RS0 Q9BYK8 Q9BZK7	AIB3 ARC205 BAF60C BHLHD1 BHLHE74 BHLHE75 CARM1 CBP CHD9 CPT1 CPT1A CREBBP CRSP1 CRSP200 DRIP205 DRIP230 EP300 HCA137 HELZ2 IRA1 KIAA0181 KIAA0308 KIAA1769 KISH2 MED1 NCOA1 NCOA2 NCOA6 NCOA6IP NR1C1 NR1F1 NR2B1 P300 PBP PIMT PPAR PPARA PPARBP PPARGBP PRIC285 PRIC320 PRMT4 RAP250 RB18A RORA RXRA RZRA SMARCD3 SRC1 SRC2 SREBF1 SREBP1 TBL1 TBL1X TBL1XR1 TBLR1 TGS1 TIF2 TRAP220 TRBP TRIP2	Homo sapiens (human)
Ubiquitin-dependent degradation of Cyclin D	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cyclin-dependent kinase 4 G1/S-specific cyclin-D1 Glycogen synthase kinase-3 beta Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O43242 O75832 P0CG47 P0CG48 P11802 P17980 P20618 P24385 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P49841 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q06323 Q13200 Q14997 Q15008 Q16401 Q8TAA3 Q92530 Q99436 Q99460 Q9UL46 Q9UNM6	BCL1 C7orf76 CCND1 CDK4 DSS1 GSK3B HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0077 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NU PFAAP4 POH1 PRAD1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RING10 RING12 RPS27A SEM1 SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 Z	Homo sapiens (human)
sunitinib-resistant FLT3 mutants	Receptor-type tyrosine-protein kinase FLT3	P36888	CD135 FLK2 FLT3 STK1	Homo sapiens (human)
APOBEC3G mediated resistance to HIV-1 infection	Barrier-to-autointegration factor Gag polyprotein Gag-Pol polyprotein High mobility group protein HMG-I/HMG-Y PC4 and SFRS1-interacting protein Peptidyl-prolyl cis-trans isomerase A Protein Rev Protein Vpr Protein Vpu Virion infectivity factor	O75475 O75531 P04585 P04591 P04618 P05919 P17096 P62937 P69723 P69726	BAF BANF1 BCRG1 CYPA DFS70 HMGA1 HMGIY LEDGF PPIA PSIP1 PSIP2 gag gag-pol rev vif vpr vpu	Homo sapiens (human)
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation	Catenin beta-1 Cyclin-dependent kinase 2 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 2A G1/S-specific cyclin-D1 G2/mitotic-specific cyclin-B1 Hepatocyte growth factor receptor Lymphoid enhancer-binding factor 1 Serine/threonine-protein kinase PLK1 T-box transcription factor TBX2 Transcription factor 7-like 1 Transcription factor 7-like 2 Transcription factor 7	P08581 P14635 P24385 P24941 P35222 P36402 P38936 P42771 P53350 Q13207 Q9HCS4 Q9NQB0 Q9UJU2	BCL1 CAP20 CCNB CCNB1 CCND1 CDK2 CDKN1 CDKN1A CDKN2 CDKN2A CIP1 CTNNB CTNNB1 LEF1 MDA6 MET MTS1 PIC1 PLK PLK1 PRAD1 SDI1 TBX2 TCF1 TCF3 TCF4 TCF7 TCF7L1 TCF7L2 WAF1	Homo sapiens (human)
RUNX2 regulates genes involved in differentiation of myeloid cells	Core-binding factor subunit beta Galectin-3 Runt-related transcription factor 1	P17931 Q01196 Q13951	AML1 CBFA2 CBFB LGALS3 MAC2 RUNX1	Homo sapiens (human)
MyD88 deficiency (TLR5)	Flagellin Myeloid differentiation primary response protein MyD88 Toll-like receptor 5	O60602 P04949 Q99836	MYD88 TIL3 TLR5 flaF fliC hag	Homo sapiens (human)
Loss of function of TP53 in cancer due to loss of tetramerization ability	Cellular tumor antigen p53	P04637	P53 TP53	Homo sapiens (human)
Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization	ADP/ATP translocase 1 ADP/ATP translocase 2 ADP/ATP translocase 3 Protein Vpr	P05141 P12235 P12236 P69726	AAC1 AAC2 AAC3 ANT1 ANT2 ANT3 SLC25A4 SLC25A5 SLC25A6 vpr	Homo sapiens (human)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	Collagen alpha-2(I) chain Cyclin-C Cyclin-K Cyclin-T1 Cyclin-T2 Cyclin-dependent kinase 4 inhibitor B Cyclin-dependent kinase 8 Cyclin-dependent kinase 9 E3 ubiquitin-protein ligase Arkadia Furin Histone acetyltransferase p300 Histone deacetylase 1 Homeobox protein TGIF1 Homeobox protein TGIF2 Menin Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Mothers against decapentaplegic homolog 7 Myc proto-oncogene protein Plasminogen activator inhibitor 1 Polyubiquitin-B Polyubiquitin-C Retinoblastoma-like protein 1 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F4 Transcription factor E2F5 Transcription factor JunB Transcription factor Sp1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein WW domain-containing transcription regulator protein 1 Y-box-binding protein 1	O00255 O15105 O60563 O60583 O75909 P01106 P05121 P08047 P08123 P09958 P0CG47 P0CG48 P17275 P24863 P27361 P28482 P28749 P42772 P49336 P50750 P62979 P62987 P67809 P84022 Q09472 Q13485 Q13547 Q14186 Q14188 Q15329 Q15583 Q15796 Q16254 Q6ZNA4 Q9GZN2 Q9GZV5	BHLHE39 CCNC CCNK CCNT1 CCNT2 CDC2L4 CDK8 CDK9 CDKN2B COL1A2 CPR4 DP1 DP2 DPC4 E2F4 E2F5 EP300 ERK1 ERK2 FUR FURIN HDAC1 JUNB MADH2 MADH3 MADH4 MADH7 MADH8 MADR2 MAPK1 MAPK3 MEN1 MTS2 MYC NSEP1 P300 PACE PAI1 PCSK3 PLANH1 PRKM1 PRKM2 PRKM3 RBL1 RNF111 RPD3L1 RPS27A SCG2 SERPINE1 SMAD2 SMAD3 SMAD4 SMAD7 SP1 TAK TAZ TFDP1 TFDP2 TGIF TGIF1 TGIF2 TSFP1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WWTR1 YB1 YBX1	Homo sapiens (human)
Synthesis of PIPs at the early endosome membrane	1-phosphatidylinositol 3-phosphate 5-kinase Inositol polyphosphate 4-phosphatase type II Inositol polyphosphate-4-phosphatase type I A Myotubularin-related protein 10 Myotubularin-related protein 12 Myotubularin-related protein 2 Myotubularin-related protein 4 Myotubularin Phosphatidylinositide phosphatase SAC2 Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphatidylinositol 4-kinase type 2-alpha Phosphatidylinositol 4-kinase type 2-beta Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha Phosphoinositide 3-kinase regulatory subunit 4 Polyphosphoinositide phosphatase Protein VAC14 homolog	O00443 O15327 Q08AM6 Q13496 Q13614 Q8NEB9 Q8TCG2 Q92562 Q96PE3 Q99570 Q9BTU6 Q9C0I1 Q9NXD2 Q9NYA4 Q9Y2H2 Q9Y2I7	CG2 FIG4 INPP4A INPP4B INPP5F KIAA0274 KIAA0647 KIAA0966 KIAA0981 KIAA1073 KIAA1682 MTM1 MTMR10 MTMR12 MTMR2 MTMR4 PI4K2A PI4K2B PIK3C2A PIK3C3 PIK3R4 PIKFYVE PIP3AP PIP5K3 SAC2 SAC3 TAX1BP2 TRX VAC14 VPS15 VPS34 ZFYVE11	Homo sapiens (human)
VEGFA-VEGFR2 Pathway	Abl interactor 1 Abl interactor 2 Actin-binding protein WASF1 Actin-binding protein WASF2 Actin-binding protein WASF3 Adapter molecule crk BAR/IMD domain-containing adapter protein 2 Breast cancer anti-estrogen resistance protein 1 Cell division control protein 42 homolog Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytoplasmic FMR1-interacting protein 1 Cytoplasmic FMR1-interacting protein 2 Cytoplasmic protein NCK2 Dedicator of cytokinesis protein 1 Engulfment and cell motility protein 1 Engulfment and cell motility protein 2 Focal adhesion kinase 1 Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Heat shock protein HSP 90-alpha Heat shock protein beta-1 Integrin alpha-V Integrin beta-3 MAP kinase-activated protein kinase 2 MAP kinase-activated protein kinase 3 Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 12 Mitogen-activated protein kinase 13 Mitogen-activated protein kinase 14 Nck-associated protein 1-like Nck-associated protein 1 Neutrophil cytosol factor 1 Neutrophil cytosol factor 2 Neutrophil cytosol factor 4 Paxillin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Protein BRICK1 Protein-tyrosine kinase 2-beta Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Rho-associated protein kinase 1 Rho-associated protein kinase 2 SH2 domain-containing adapter protein B SH2 domain-containing protein 2A SH2/SH3 adapter protein NCK1 SHC-transforming protein 2 Serine/threonine-protein kinase PAK 2 Transforming protein RhoA Tyrosine-protein kinase Fyn Tyrosine-protein kinase receptor UFO Vascular endothelial growth factor receptor 2 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	O00459 O15264 O43639 O75116 P04792 P04839 P05106 P06241 P06756 P07900 P13498 P14598 P15498 P16333 P17612 P19878 P22612 P22694 P27986 P30530 P35968 P42336 P42338 P46108 P49023 P49137 P52735 P53778 P55160 P56945 P60953 P61586 P63000 P98077 Q05397 Q13177 Q13464 Q14185 Q14289 Q15080 Q15464 Q15759 Q16539 Q16644 Q7L576 Q8IZP0 Q8WUW1 Q92556 Q92558 Q96F07 Q96JJ3 Q9NP31 Q9NYB9 Q9UKW4 Q9UPY6 Q9UQB8 Q9Y2A7 Q9Y6W5	ABI1 ABI2 ARGBPIA ARH12 ARHA AXL BAIAP2 BCAR1 BRK1 C3orf10 CAS CASS1 CDC42 CED12A CRK CRKAS CSBP CSBP1 CSBP2 CSPB1 CYBA CYBB CYFIP1 CYFIP2 DOCK1 ELMO1 ELMO2 ERK6 FAK FAK1 FAK2 FLK1 FYN GP3A GRB1 GRB4 HEM1 HEM2 HSP27 HSP28 HSP90A HSP90AA1 HSPB1 HSPC1 HSPCA ITGAV ITGB3 KDR KIAA0068 KIAA0269 KIAA0281 KIAA0587 KIAA0619 KIAA0900 KIAA1168 KIAA1834 MAPK11 MAPK12 MAPK13 MAPK14 MAPKAPK2 MAPKAPK3 MSK8 MXI2 NAP1 NCF1 NCF2 NCF4 NCK NCK1 NCK2 NCKAP1 NCKAP1L NOX2 NOXA2 NOXO2 P67PHOX PAK2 PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 PIR121 PKACA PRKACA PRKACB PRKACG PRKM11 PRKM13 PTK2 PTK2B PXN PYK2 RAC1 RAFTK RHO12 RHOA ROCK1 ROCK2 SAPK2 SAPK2A SAPK2B SAPK3 SAPK4 SCAP SCAR1 SCAR3 SCK SH2D2A SH3PXD1A SH3PXD4 SHB SHC2 SHCB SSH3BP1 TC25 TSAD UFO VAV VAV1 VAV2 VAV3 VEGFR2 VNRA VRAP VTNR WASF1 WASF2 WASF3 WAVE1 WAVE2 WAVE3	Homo sapiens (human)
Defective SLC5A5 causes thyroid dyshormonogenesis 1 (TDH1)	Sodium/iodide cotransporter	Q92911	NIS SLC5A5	Homo sapiens (human)
IRAK4 deficiency (TLR2/4)	Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain High mobility group protein B1 Interleukin-1 receptor-associated kinase 4 Lymphocyte antigen 96 Major outer membrane protein P.IB Monocyte differentiation antigen CD14 Myeloid differentiation primary response protein MyD88 Peptidyl-prolyl cis-trans isomerase Mip Platelet glycoprotein 4 Protein S100-A1 Protein S100-A8 Protein S100-A9 Toll-like receptor 1 Toll-like receptor 2 Toll-like receptor 4 Toll-like receptor 6 Toll/interleukin-1 receptor domain-containing adapter protein Tyrosine-protein kinase BTK	O00206 O60603 P02671 P02675 P02679 P05109 P06702 P08571 P09429 P16671 P23297 P26623 P30690 P58753 Q06187 Q15399 Q99836 Q9NWZ3 Q9Y2C9 Q9Y6Y9	AGMX1 ATK BPK BTK CAGA CAGB CD14 CD36 CFAG ESOP1 FGA FGB FGG GP3B GP4 HMG1 HMGB1 IRAK4 KIAA0012 LY96 MAL MD2 MRP14 MRP8 MYD88 S100A S100A1 S100A8 S100A9 TIL4 TIRAP TLR1 TLR2 TLR4 TLR6 mip porB	Homo sapiens (human)
NTRK3 as a dependence receptor	Apoptosis regulator BAX NT-3 growth factor receptor Negative elongation factor B	Q07812 Q16288 Q8WX92	BAX BCL2L4 COBRA1 KIAA1182 NELFB NTRK3 TRKC	Homo sapiens (human)
Ethanol oxidation	Acetyl-coenzyme A synthetase 2-like, mitochondrial Acetyl-coenzyme A synthetase, cytoplasmic Alcohol dehydrogenase 1A Alcohol dehydrogenase 1C Alcohol dehydrogenase 6 Alcohol dehydrogenase class-3 Aldehyde dehydrogenase 1A1 Aldehyde dehydrogenase X, mitochondrial Aldehyde dehydrogenase, mitochondrial All-trans-retinol dehydrogenase [NAD(+)] ADH1B All-trans-retinol dehydrogenase [NAD(+)] ADH4 All-trans-retinol dehydrogenase [NAD(+)] ADH7	P00325 P00326 P00352 P05091 P07327 P08319 P11766 P28332 P30837 P40394 Q9NR19 Q9NUB1	ACAS2 ACAS2L ACSS1 ACSS2 ADH1 ADH1A ADH1B ADH1C ADH2 ADH3 ADH4 ADH5 ADH6 ADH7 ADHX ALDC ALDH1 ALDH1A1 ALDH1B1 ALDH2 ALDH5 ALDHX ALDM FDH KIAA1846 PUMB1	Homo sapiens (human)
MET activates PTPN11	GRB2-associated-binding protein 1 Hepatocyte growth factor receptor Hepatocyte growth factor Tyrosine-protein phosphatase non-receptor type 11	P08581 P14210 Q06124 Q13480	GAB1 HGF HPTA MET PTP2C PTPN11 SHPTP2	Homo sapiens (human)
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome	ATP-binding cassette sub-family C member 9 ATP-sensitive inward rectifier potassium channel 11	O60706 Q14654	ABCC9 KCNJ11 SUR2	Homo sapiens (human)
trans-Golgi Network Vesicle Budding	ADP-ribosylation factor 1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 Synaptosomal-associated protein 23 Syntaxin-4 Vesicle-associated membrane protein 2 Vesicle-associated membrane protein 7 Vesicle-associated membrane protein 8	O00161 P51809 P63027 P84077 Q12846 Q92538 Q9BV40	ARF1 GBF1 KIAA0248 SNAP23 STX4 STX4A SYB2 SYBL1 VAMP2 VAMP7 VAMP8	Homo sapiens (human)

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