GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **51 - 75** of **2090** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	GlyTouCan ID
Phospholipase C-mediated cascade; FGFR2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9	O15520 O43320 O76093 P05230 P08620 P09038 P10767 P11487 P19174 P21781 P31371 Q9GZV9 Q9HCT0 Q9NP95	FGF1 FGF10 FGF16 FGF18 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB HST HST2 HSTF1 HSTF2 HYPF INT2 KGF KS3 PLC1 PLCG1
Signaling by FGFR3 in disease	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 9 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor substrate 2 GRB2-associated-binding protein 1 GTPase HRas GTPase NRas Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Son of sevenless homolog 1	O43320 O76093 P01111 P01112 P05230 P08620 P09038 P19174 P22607 P27986 P31371 P42336 Q07889 Q13480 Q8WU20 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF2 FGF20 FGF23 FGF4 FGF9 FGFA FGFB FGFR3 FRS2 GAB1 GRB1 HRAS HRAS1 HST HSTF1 HYPF JTK4 KS3 NRAS PIK3CA PIK3R1 PLC1 PLCG1 SOS1
Phospholipase C-mediated cascade; FGFR3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 9	O43320 O76093 P05230 P08620 P09038 P19174 P31371 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF2 FGF20 FGF23 FGF4 FGF9 FGFA FGFB HST HSTF1 HYPF KS3 PLC1 PLCG1
Signaling by FGFR4 in disease	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 GRB2-associated-binding protein 1 GTPase HRas GTPase NRas Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Son of sevenless homolog 1	P01111 P01112 P19174 P22455 P27986 P42336 Q07889 Q13480 Q8WU20	FGFR4 FRS2 GAB1 GRB1 HRAS HRAS1 JTK2 NRAS PIK3CA PIK3R1 PLC1 PLCG1 SOS1 TKF
DAG and IP3 signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Protein kinase C delta type Protein kinase C epsilon type S-adenosylhomocysteine hydrolase-like protein 1	O43865 P19174 Q02156 Q05655 Q14571 Q14573 Q14643	AHCYL1 DCAL INSP3R1 IRBIT ITPR1 ITPR2 ITPR3 PKCD PKCE PLC1 PLCG1 PRKCD PRKCE XPVKONA
PECAM1 interactions	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Integrin alpha-V Integrin beta-3 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Platelet endothelial cell adhesion molecule Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lck Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6	P05106 P06239 P06241 P06756 P07947 P07948 P16284 P19174 P29350 Q06124 Q92835	FYN GP3A HCP INPP5D ITGAV ITGB3 JTK8 LCK LYN MSK8 PECAM1 PLC1 PLCG1 PTP1C PTP2C PTPN11 PTPN6 SHIP SHIP1 SHPTP2 VNRA VTNR YES YES1
Activated NTRK3 signals through PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 NT-3 growth factor receptor Neurotrophin-3	P19174 P20783 Q16288	NTF3 NTRK3 PLC1 PLCG1 TRKC
Role of second messengers in netrin-1 signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Netrin receptor DCC Netrin-1 Phosphatidylinositol transfer protein alpha isoform Short transient receptor potential channel 1 Short transient receptor potential channel 3 Short transient receptor potential channel 4 Short transient receptor potential channel 5 Short transient receptor potential channel 6 Short transient receptor potential channel 7	O95631 P19174 P43146 P48995 Q00169 Q13507 Q9HCX4 Q9UBN4 Q9UL62 Q9Y210	DCC IGDCC1 NTN1 NTN1L PITPN PITPNA PLC1 PLCG1 TRP1 TRP3 TRP5 TRP6 TRP7 TRPC1 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7
CLEC7A (Dectin-1) signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 3-phosphoinositide-dependent protein kinase 1 B-cell lymphoma/leukemia 10 C-type lectin domain family 7 member A Caspase recruitment domain-containing protein 11 Caspase recruitment domain-containing protein 9 Cullin-1 F-box/WD repeat-containing protein 11 F-box/WD repeat-containing protein 1A Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Mitogen-activated protein kinase kinase kinase 7 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein kinase C delta type S-phase kinase-associated protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 6 Transcription factor p65 Tyrosine-protein kinase SYK Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 R1 Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O14920 O15111 O15530 O43242 O43318 O75832 O95999 P0CG47 P0CG48 P16885 P17980 P19838 P20618 P25786 P25787 P25788 P25789 P25963 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43405 P43686 P48556 P49427 P49720 P49721 P51665 P51668 P55036 P60896 P60900 P61088 P61289 P62191 P62195 P62333 P62837 P62979 P62987 P63208 Q04206 Q05655 Q06323 Q13200 Q13404 Q13616 Q14997 Q15008 Q15750 Q16401 Q8N5C8 Q8TAA3 Q92530 Q99436 Q99460 Q9BXL7 Q9BXN2 Q9H257 Q9NYJ8 Q9UDY8 Q9UKB1 Q9UL46 Q9UNM6 Q9Y297 Q9Y4K3 Q9Y6K9	BCL10 BGR BLU BTRC BTRCP BTRCP2 C7orf76 CARD11 CARD9 CARMA1 CDC34 CHUK CIPER CLAP CLEC7A CLECSF12 CROC1 CUL1 DECTIN1 DSS1 EMC19 FBW1A FBW1B FBXW11 FBXW1A FBXW1B FIP3 HC2 HC3 HC8 HC9 HSPC IFI5111 IKBA IKBKB IKBKG IKKA IKKB KIAA0072 KIAA0077 KIAA0107 KIAA0696 KIAA0733 LMP10 LMP2 LMP7 LMPX LMPY MAD3 MALT1 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MB1 MCB1 MECL1 MIP224 MLT MOV34L MSS1 NEMO NFKB1 NFKB3 NFKBI NFKBIA NU OCP2 PDK1 PDPK1 PFAAP4 PKCD PLCG2 POH1 PRKCD PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 PUBC1 RELA RING10 RING12 RNF85 RPS27A SEM1 SFT SHFDG1 SHFM1 SKP1 SKP1A SUG1 SUG2 SYK TAB1 TAB2 TAB3 TAK1 TBP1 TBP7 TCEB1L TCF16 TRAF6 TRAP2 UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBCEP1 UBCEP2 UBCH3 UBCH4 UBCH5 UBCH5A UBCH5B UBE2D1 UBE2D2 UBE2N UBE2R1 UBE2V UBE2V1 UEV1 X Y Y2 Z
GPVI-mediated activation cascade	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 3-phosphoinositide-dependent protein kinase 1 C-type lectin domain family 1 member B Cell division control protein 42 homolog Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 High affinity immunoglobulin epsilon receptor subunit gamma Linker for activation of T-cells family member 1 Lymphocyte cytosolic protein 2 Megakaryocyte and platelet inhibitory receptor G6b Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Phosphoinositide 3-kinase regulatory subunit 5 Phosphoinositide 3-kinase regulatory subunit 6 Platelet glycoprotein VI Podoplanin Protein kinase C zeta type Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 2 Rho-related GTP-binding protein RhoB Rho-related GTP-binding protein RhoG Transforming protein RhoA Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lck Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6	O00459 O15530 O43561 O95866 P06239 P06241 P07948 P15153 P15498 P16885 P27986 P29350 P30273 P42336 P42338 P43405 P48736 P52735 P60953 P61586 P62745 P63000 P84095 Q05513 Q06124 Q13094 Q5UE93 Q86YL7 Q8WYR1 Q92569 Q9HCN6 Q9P126 Q9UKW4	ARH12 ARH6 ARHA ARHB ARHG C17orf38 C6orf25 CDC42 CLEC1B CLEC2 FCER1G FYN G6B G6B-B GP36 GP6 GRB1 HCP JTK8 LAT LCK LCP2 LYN MPIG6B PDK1 PDPK1 PDPN PIK3C1 PIK3CA PIK3CB PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PIK3R6 PKC2 PLCG2 PRKCZ PTP1C PTP2C PTPN11 PTPN6 RAC1 RAC2 RHO12 RHOA RHOB RHOG SHPTP2 SYK TC25 VAV VAV1 VAV2 VAV3
Potential therapeutics for SARS	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma AT-rich interactive domain-containing protein 4A AT-rich interactive domain-containing protein 4B Angiotensin-converting enzyme 2 B-cell antigen receptor complex-associated protein alpha chain B-cell antigen receptor complex-associated protein beta chain B-cell linker protein Breast cancer metastasis-suppressor 1 Bromodomain-containing protein 4 Catechol O-methyltransferase Chromodomain-helicase-DNA-binding protein 3 Chromodomain-helicase-DNA-binding protein 4 Cullin-3 Cysteinyl leukotriene receptor 1 E3 ubiquitin-protein ligase RBX1 FXYD domain-containing ion transport regulator 3 FXYD domain-containing ion transport regulator 4 FXYD domain-containing ion transport regulator 6 FXYD domain-containing ion transport regulator 7 Furin Glucocorticoid receptor Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Histone deacetylase 1 Histone deacetylase 2 Histone deacetylase complex subunit SAP18 Histone deacetylase complex subunit SAP30 Histone deacetylase complex subunit SAP30L Histone-binding protein RBBP4 Histone-binding protein RBBP7 IGHV7-81 protein Immunoglobulin heavy constant delta Immunoglobulin heavy constant mu Immunoglobulin heavy variable 1-2 Immunoglobulin heavy variable 1-46 Immunoglobulin heavy variable 1-69 Immunoglobulin heavy variable 2-5 Immunoglobulin heavy variable 2-70 Immunoglobulin heavy variable 3-11 Immunoglobulin heavy variable 3-13 Immunoglobulin heavy variable 3-23 Immunoglobulin heavy variable 3-30 Immunoglobulin heavy variable 3-33 Immunoglobulin heavy variable 3-48 Immunoglobulin heavy variable 3-53 Immunoglobulin heavy variable 3-7 Immunoglobulin heavy variable 3-9 Immunoglobulin heavy variable 4-34 Immunoglobulin heavy variable 4-39 Immunoglobulin heavy variable 4-59 Immunoglobulin kappa constant Immunoglobulin kappa variable 1-12 Immunoglobulin kappa variable 1-16 Immunoglobulin kappa variable 1-17 Immunoglobulin kappa variable 1-33 Immunoglobulin kappa variable 1-39 Immunoglobulin kappa variable 1-5 Immunoglobulin kappa variable 1D-12 Immunoglobulin kappa variable 1D-16 Immunoglobulin kappa variable 1D-33 Immunoglobulin kappa variable 1D-39 Immunoglobulin kappa variable 2-28 Immunoglobulin kappa variable 2-29 Immunoglobulin kappa variable 2-30 Immunoglobulin kappa variable 2D-28 Immunoglobulin kappa variable 2D-30 Immunoglobulin kappa variable 2D-40 Immunoglobulin kappa variable 3-11 Immunoglobulin kappa variable 3-15 Immunoglobulin kappa variable 3-20 Immunoglobulin kappa variable 3D-20 Immunoglobulin kappa variable 4-1 Immunoglobulin kappa variable 5-2 Immunoglobulin lambda constant 1 Immunoglobulin lambda constant 2 Immunoglobulin lambda constant 3 Immunoglobulin lambda constant 6 Immunoglobulin lambda constant 7 Immunoglobulin lambda variable 1-40 Immunoglobulin lambda variable 1-44 Immunoglobulin lambda variable 1-47 Immunoglobulin lambda variable 1-51 Immunoglobulin lambda variable 2-11 Immunoglobulin lambda variable 2-14 Immunoglobulin lambda variable 2-23 Immunoglobulin lambda variable 2-8 Immunoglobulin lambda variable 3-19 Immunoglobulin lambda variable 3-1 Immunoglobulin lambda variable 3-21 Immunoglobulin lambda variable 3-25 Immunoglobulin lambda variable 3-27 Immunoglobulin lambda variable 6-57 Immunoglobulin lambda variable 7-43 Immunolglobulin kappa light chain variable region L22 (Fragment) Inosine-5'-monophosphate dehydrogenase 1 Inosine-5'-monophosphate dehydrogenase 2 Integrin alpha-4 Integrin beta-1 Interferon alpha/beta receptor 1 Interferon gamma receptor 1 Interferon gamma receptor 2 Interleukin-1 receptor type 1 Interleukin-6 receptor subunit alpha Kelch-like ECH-associated protein 1 Lysine-specific histone demethylase 1A Metastasis-associated protein MTA1 Metastasis-associated protein MTA2 Metastasis-associated protein MTA3 Methyl-CpG-binding domain protein 3 Non-receptor tyrosine-protein kinase TYK2 Nuclear factor erythroid 2-related factor 2 PHD finger protein 21A Peptidyl-prolyl cis-trans isomerase FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP4 Phospholemman Programmed cell death protein 1 Prostaglandin E synthase 3 Protein cereblon Protein farnesyltransferase subunit beta Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha Proto-oncogene vav RE1-silencing transcription factor REST corepressor 1 RNA-directed RNA polymerase (Fragment) Receptor-interacting serine/threonine-protein kinase 1 Rho-associated protein kinase 1 Rho-associated protein kinase 2 SH2/SH3 adapter protein NCK1 SH3 domain-containing kinase-binding protein 1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related Serine/threonine-protein kinase TBK1 Sigma non-opioid intracellular receptor 1 Signal transducer and activator of transcription 2 Sin3 histone deacetylase corepressor complex component SDS3 Sodium/potassium-transporting ATPase subunit alpha-1 Sodium/potassium-transporting ATPase subunit alpha-2 Sodium/potassium-transporting ATPase subunit alpha-3 Sodium/potassium-transporting ATPase subunit alpha-4 Sodium/potassium-transporting ATPase subunit beta-1 Sodium/potassium-transporting ATPase subunit beta-2 Sodium/potassium-transporting ATPase subunit beta-3 Sodium/potassium-transporting ATPase subunit gamma Son of sevenless homolog 1 Sphingosine 1-phosphate receptor 1 Toll-like receptor 7 Toll-like receptor 9 Transcriptional repressor p66-alpha Transcriptional repressor p66-beta Tubulin beta chain Tyrosine-protein kinase BTK Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase JAK3 Tyrosine-protein kinase SYK UGa8H (Fragment) Z-DNA-binding protein 1	A0A075B6P5 A0A075B6S6 A0A0C4DH25 A0A0C4DH73 A0M8Q6 A2KUC3 A2NJV5 A2NXD2 O00168 O00422 O60341 O60674 O60885 O75116 O75446 O94776 O94973 O95782 O95983 P01593 P01594 P01597 P01599 P01601 P01602 P01611 P01614 P01615 P01619 P01624 P01699 P01700 P01701 P01703 P01704 P01705 P01706 P01709 P01714 P01715 P01717 P01718 P01721 P01742 P01743 P01762 P01763 P01764 P01766 P01767 P01768 P01772 P01780 P01782 P01814 P01817 P01824 P01825 P01834 P01871 P01880 P04150 P04211 P04430 P04432 P04433 P05023 P05026 P05556 P06310 P06312 P06315 P06331 P07437 P07900 P08238 P08887 P09958 P0CF74 P0CG04 P0DOY2 P0DOY3 P11912 P12268 P13612 P13637 P14415 P14778 P15260 P15498 P16333 P16885 P17181 P20839 P21453 P21964 P23083 P23458 P29374 P29597 P38484 P40259 P43405 P49354 P49356 P50993 P52333 P52630 P53680 P54709 P54710 P58549 P59646 P62877 P62942 P63010 P80748 Q02790 Q06187 Q07889 Q09028 Q12873 Q13127 Q13330 Q13464 Q13546 Q13547 Q13618 Q13733 Q14145 Q14802 Q14839 Q15116 Q15185 Q16236 Q16576 Q4LE39 Q6PIL0 Q86YP4 Q8JXU8 Q8WV28 Q8WXI9 Q92769 Q96B97 Q96BD5 Q96CW1 Q96SW2 Q99720 Q9BTC8 Q9BYF1 Q9H0Q3 Q9H171 Q9H7L9 Q9HAJ7 Q9HCU9 Q9NR96 Q9NYK1 Q9P0W2 Q9UHD2 Q9UKL0 Q9Y271	ACE2 ADTAA ADTAB ADTB2 AGMX1 AOF2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 ARID4A ARID4B ATK ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1AL2 ATP1B ATP1B1 ATP1B2 ATP1B3 ATP1C ATP1G1 B29 BASH BHC80 BLNK BPK BRAF35 BRCAA1 BRD4 BRMS1 BTK C20orf183 CD49D CD79A CD79B CHD3 CHD4 CHEDG1 CIN85 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 COMT CRBN CUL3 CYSLT1 CYSLTR1 DLM1 EDG1 FKBP1 FKBP12 FKBP1A FKBP4 FKBP52 FNRB FNTA FNTB FUR FURIN FXYD1 FXYD2 FXYD3 FXYD4 FXYD6 FXYD7 GATAD2A GATAD2B GRL HDAC1 HDAC2 HIP9 HMG20B HMGX2 HMGXB2 HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB HUNK1 HYPJ IFNAR IFNAR1 IFNGR1 IFNGR2 IFNGT1 IGA IGB IGHD IGHM IGHV IGHV1-2 IGHV1-46 IGHV1-69 IGHV2-5 IGHV2-70 IGHV3-11 IGHV3-13 IGHV3-23 IGHV3-30 IGHV3-33 IGHV3-48 IGHV3-53 IGHV3-7 IGHV3-9 IGHV4-34 IGHV4-39 IGHV4-59 IGHV7-81 IGKC IGKV1-12 IGKV1-16 IGKV1-17 IGKV1-33 IGKV1-39 IGKV1-5 IGKV1D-12 IGKV1D-16 IGKV1D-33 IGKV1D-39 IGKV2-28 IGKV2-29 IGKV2-30 IGKV2D-28 IGKV2D-30 IGKV2D-40 IGKV3-11 IGKV3-15 IGKV3-20 IGKV3D-20 IGKV4-1 IGKV5-2 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7 IGLV IGLV1-40 IGLV1-44 IGLV1-47 IGLV1-51 IGLV2-11 IGLV2-14 IGLV2-23 IGLV2-8 IGLV3-1 IGLV3-19 IGLV3-21 IGLV3-25 IGLV3-27 IGLV6-57 IGLV7-43 IL1R IL1R1 IL1RA IL1RT1 IL6R IMPD1 IMPD2 IMPDH1 IMPDH2 INRF2 ITGA4 ITGB1 JAK1 JAK1A JAK1B JAK2 JAK3 KDM1 KDM1A KEAP1 KIAA0071 KIAA0109 KIAA0132 KIAA0601 KIAA0617 KIAA0619 KIAA0778 KIAA0899 KIAA1150 KIAA1266 KIAA1696 KLHL19 LSD1 MAT8 MB1 MBD3 MDF2 MSK12 MTA1 MTA1L1 MTA2 MTA3 NAK NCK NCK1 NFE2L2 NR3C1 NRF2 NRSF NS4ATP2 NS5B OPRS1 P23 PACE PCSK3 PD1 PDCD1 PHF21A PID PLCG2 PLM PLML PTGES3 RBAP46 RBAP48 RBBP1 RBBP1L1 RBBP4 RBBP7 RBP1 RBP1L1 RBX1 RCOR RCOR1 REST RIP RIP1 RIPK1 RNF75 ROC1 ROCK1 ROCK2 RPD3L1 S1PR1 SAP18 SAP180 SAP30 SAP30L SAP45 SDS3 SH3KBP1 SIGMAR1 SLP65 SMARCE1R SOS1 SRBP STAT2 SUDS3 SYK TBK1 TEBP TLR7 TLR9 TUBB TUBB5 TYK2 VAV VAV1 XBR ZBP1
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 B-cell antigen receptor complex-associated protein alpha chain B-cell antigen receptor complex-associated protein beta chain B-cell linker protein B-cell receptor CD22 B-lymphocyte antigen CD19 Calcium release-activated calcium channel protein 1 Calmodulin-1 Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide IGHV7-81 protein Immunoglobulin heavy constant delta Immunoglobulin heavy constant mu Immunoglobulin heavy variable 1-2 Immunoglobulin heavy variable 1-46 Immunoglobulin heavy variable 1-69 Immunoglobulin heavy variable 2-5 Immunoglobulin heavy variable 2-70 Immunoglobulin heavy variable 3-11 Immunoglobulin heavy variable 3-13 Immunoglobulin heavy variable 3-23 Immunoglobulin heavy variable 3-30 Immunoglobulin heavy variable 3-33 Immunoglobulin heavy variable 3-48 Immunoglobulin heavy variable 3-53 Immunoglobulin heavy variable 3-7 Immunoglobulin heavy variable 3-9 Immunoglobulin heavy variable 4-34 Immunoglobulin heavy variable 4-39 Immunoglobulin heavy variable 4-59 Immunoglobulin kappa constant Immunoglobulin kappa variable 1-12 Immunoglobulin kappa variable 1-16 Immunoglobulin kappa variable 1-17 Immunoglobulin kappa variable 1-33 Immunoglobulin kappa variable 1-39 Immunoglobulin kappa variable 1-5 Immunoglobulin kappa variable 1D-12 Immunoglobulin kappa variable 1D-16 Immunoglobulin kappa variable 1D-33 Immunoglobulin kappa variable 1D-39 Immunoglobulin kappa variable 2-28 Immunoglobulin kappa variable 2-29 Immunoglobulin kappa variable 2-30 Immunoglobulin kappa variable 2D-28 Immunoglobulin kappa variable 2D-30 Immunoglobulin kappa variable 2D-40 Immunoglobulin kappa variable 3-11 Immunoglobulin kappa variable 3-15 Immunoglobulin kappa variable 3-20 Immunoglobulin kappa variable 3D-20 Immunoglobulin kappa variable 4-1 Immunoglobulin kappa variable 5-2 Immunoglobulin lambda constant 1 Immunoglobulin lambda constant 2 Immunoglobulin lambda constant 3 Immunoglobulin lambda constant 6 Immunoglobulin lambda constant 7 Immunoglobulin lambda variable 1-40 Immunoglobulin lambda variable 1-44 Immunoglobulin lambda variable 1-47 Immunoglobulin lambda variable 1-51 Immunoglobulin lambda variable 2-11 Immunoglobulin lambda variable 2-14 Immunoglobulin lambda variable 2-23 Immunoglobulin lambda variable 2-8 Immunoglobulin lambda variable 3-19 Immunoglobulin lambda variable 3-1 Immunoglobulin lambda variable 3-21 Immunoglobulin lambda variable 3-25 Immunoglobulin lambda variable 3-27 Immunoglobulin lambda variable 6-57 Immunoglobulin lambda variable 7-43 Immunolglobulin kappa light chain variable region L22 (Fragment) Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Phosphoinositide 3-kinase adapter protein 1 Protein orai-2 Proto-oncogene vav S-adenosylhomocysteine hydrolase-like protein 1 SH2/SH3 adapter protein NCK1 SH3 domain-containing kinase-binding protein 1 Short transient receptor potential channel 1 Son of sevenless homolog 1 Stromal interaction molecule 1 Tyrosine-protein kinase BTK Tyrosine-protein kinase Blk Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Tyrosine-protein phosphatase non-receptor type 6 UGa8H (Fragment)	A0A075B6P5 A0A075B6S6 A0A0C4DH25 A0A0C4DH73 A0M8Q6 A2KUC3 A2NJV5 A2NXD2 O00329 O43865 P01593 P01594 P01597 P01599 P01601 P01602 P01611 P01614 P01615 P01619 P01624 P01699 P01700 P01701 P01703 P01704 P01705 P01706 P01709 P01714 P01715 P01717 P01718 P01721 P01742 P01743 P01762 P01763 P01764 P01766 P01767 P01768 P01772 P01780 P01782 P01814 P01817 P01824 P01825 P01834 P01871 P01880 P04211 P04430 P04432 P04433 P06241 P06310 P06312 P06315 P06331 P07948 P0CF74 P0CG04 P0DOY2 P0DOY3 P0DP23 P11912 P15391 P15498 P16333 P16885 P20273 P23083 P27986 P29350 P40259 P43405 P48995 P51451 P80748 Q06187 Q07889 Q13586 Q14571 Q14573 Q14643 Q6PIL0 Q6ZUJ8 Q8WV28 Q96B97 Q96D31 Q96SN7 Q9UN19	AGMX1 AHCYL1 ATK B29 BAM32 BASH BCAP BLK BLNK BPK BTK C7orf19 CALM CALM1 CAM CAM1 CBCIP2 CD19 CD22 CD79A CD79B CIN85 CRACM1 DAPP1 DCAL FYN GOK GRB1 HCP IGA IGB IGHD IGHM IGHV IGHV1-2 IGHV1-46 IGHV1-69 IGHV2-5 IGHV2-70 IGHV3-11 IGHV3-13 IGHV3-23 IGHV3-30 IGHV3-33 IGHV3-48 IGHV3-53 IGHV3-7 IGHV3-9 IGHV4-34 IGHV4-39 IGHV4-59 IGHV7-81 IGKC IGKV1-12 IGKV1-16 IGKV1-17 IGKV1-33 IGKV1-39 IGKV1-5 IGKV1D-12 IGKV1D-16 IGKV1D-33 IGKV1D-39 IGKV2-28 IGKV2-29 IGKV2-30 IGKV2D-28 IGKV2D-30 IGKV2D-40 IGKV3-11 IGKV3-15 IGKV3-20 IGKV3D-20 IGKV4-1 IGKV5-2 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7 IGLV IGLV1-40 IGLV1-44 IGLV1-47 IGLV1-51 IGLV2-11 IGLV2-14 IGLV2-23 IGLV2-8 IGLV3-1 IGLV3-19 IGLV3-21 IGLV3-25 IGLV3-27 IGLV6-57 IGLV7-43 INSP3R1 IRBIT ITPR1 ITPR2 ITPR3 JTK8 LYN MB1 NCK NCK1 ORAI1 ORAI2 PIK3AP1 PIK3CD PIK3R1 PLCG2 PTP1C PTPN6 SH3KBP1 SIGLEC2 SLP65 SOS1 STIM1 SYK TMEM142A TMEM142B TRP1 TRPC1 VAV VAV1 XPVKONA
Toll Like Receptor 4 (TLR4) Cascade	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 Bactericidal permeability-increasing protein CD180 antigen Dynamin-1 Dynamin-2 Dynamin-3 Integrin alpha-M Integrin beta-2 Lipopolysaccharide-binding protein Lymphocyte antigen 86 Lymphocyte antigen 96 Monocyte differentiation antigen CD14 TIR domain-containing adapter molecule 2 Toll-like receptor 4 Tyrosine-protein phosphatase non-receptor type 4	O00206 O95711 P05107 P08571 P11215 P16885 P17213 P18428 P29074 P50570 Q05193 Q86XR7 Q99467 Q9UQ16 Q9Y6Y9	BPI CD11B CD14 CD18 CD180 CR3A DNM DNM1 DNM2 DNM3 DYN2 ESOP1 ITGAM ITGB2 KIAA0820 LBP LY64 LY86 LY96 MD1 MD2 MFI7 PLCG2 PTPN4 RP105 TICAM2 TIRAP3 TIRP TLR4 TRAM
Dectin-2 family	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 C-type lectin domain family 10 member A C-type lectin domain family 4 member A C-type lectin domain family 4 member C C-type lectin domain family 4 member D C-type lectin domain family 4 member E C-type lectin domain family 6 member A Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Genome polyprotein High affinity immunoglobulin epsilon receptor subunit gamma Mucin-12 Mucin-13 Mucin-15 Mucin-16 Mucin-17 Mucin-19 Mucin-1 Mucin-20 Mucin-21 Mucin-2 Mucin-3A Mucin-3B Mucin-4 Mucin-5AC Mucin-5B Mucin-6 Mucin-7 Mucin-like protein 1 Truncated surface protein Truncated surface protein Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK	P03375 P03377 P03378 P04578 P04579 P04580 P04581 P04582 P04583 P04624 P05877 P05878 P05879 P05880 P05881 P05882 P06241 P07948 P12487 P12488 P12489 P12490 P12491 P15941 P16885 P18799 P19549 P19550 P19551 P20871 P20888 P30273 P31819 P31872 P35961 P43405 P98088 Q02505 Q02817 Q5SSG8 Q685J3 Q6EIG7 Q6W4X9 Q70626 Q7Z5P9 Q8IUN9 Q8N307 Q8N387 Q8TAX7 Q8WTT0 Q8WXI7 Q8WXI8 Q96DR8 Q99102 Q99IB8 Q9H195 Q9H3R2 Q9HC84 Q9UKN1 Q9ULY5 Q9UMR7	BDCA2 C6orf205 CA125 CLEC10A CLEC4A CLEC4C CLEC4D CLEC4E CLEC6A CLECSF10 CLECSF11 CLECSF13 CLECSF14 CLECSF6 CLECSF7 CLECSF8 CLECSF9 DCIR DECTIN2 DLEC DRCC1 FCER1G FYN HECL HML JTK8 KIAA1359 LLIR LYN MCL MG2 MINCLE MUC1 MUC11 MUC12 MUC13 MUC15 MUC16 MUC17 MUC19 MUC2 MUC20 MUC21 MUC3 MUC3A MUC3B MUC4 MUC5 MUC5AC MUC5B MUC6 MUC7 MUCL1 PLCG2 PUM RECC SBEM SMUC SYK env
Signaling by CSF1 (M-CSF) in myeloid cells	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 E3 ubiquitin-protein ligase CBL GRB2-associated-binding protein 2 GRB2-associated-binding protein 3 GRB2-related adapter protein 2 GTPase KRas Interleukin-34 Macrophage colony-stimulating factor 1 receptor Macrophage colony-stimulating factor 1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Polyubiquitin-B Polyubiquitin-C Proto-oncogene tyrosine-protein kinase Src SHC-transforming protein 1 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Son of sevenless homolog 1 THO complex subunit 5 homolog Tyrosine-protein kinase Fyn Tyrosine-protein kinase HCK Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00329 O15357 O75791 P01116 P06241 P07333 P07947 P07948 P08631 P09603 P0CG47 P0CG48 P12931 P16885 P22681 P27986 P29353 P40763 P42224 P42336 P42338 P62979 P62987 Q06124 Q07889 Q13769 Q6ZMJ4 Q8WWW8 Q92835 Q9UQC2	APRF C16orf77 C22orf19 CBL CBL2 CSF1 CSF1R FMS FYN GAB2 GAB3 GADS GRAP2 GRB1 GRB2L GRID HCK IL34 INPP5D INPPL1 JTK8 KIAA0571 KIAA0983 KRAS KRAS2 LYN PIK3C1 PIK3CA PIK3CB PIK3CD PIK3R1 PLCG2 PTP2C PTPN11 RASK2 RNF55 RPS27A SHC SHC1 SHCA SHIP SHIP1 SHIP2 SHPTP2 SOS1 SRC SRC1 STAT1 STAT3 THOC5 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 YES YES1
RHOG GTPase cycle	10 kDa heat shock protein, mitochondrial ADP-ribosylation factor GTPase-activating protein 3 Ankyrin repeat and LEM domain-containing protein 2 Caveolin-1 Cdc42 effector protein 1 Cell division control protein 42 homolog Cell surface glycoprotein MUC18 Cytoplasmic FMR1-interacting protein 1 DEP domain-containing protein 1B Dedicator of cytokinesis protein 1 Dedicator of cytokinesis protein 2 Dedicator of cytokinesis protein 3 Dedicator of cytokinesis protein 4 Dedicator of cytokinesis protein 5 Delta(14)-sterol reductase LBR Desmoglein-2 Emerin Engulfment and cell motility protein 2 Ephrin type-A receptor 2 Erbin Extended synaptotagmin-1 Granule associated Rac and RHOG effector protein 1 Guanine nucleotide exchange factor DBS Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Inner nuclear membrane protein Man1 Integrin beta-1 Intersectin-1 Kalirin Kinectin Lamina-associated polypeptide 2, isoforms beta/gamma MAGUK p55 subfamily member 7 Membrane-associated progesterone receptor component 2 Mitochondrial proton/calcium exchanger protein Mitogen-activated protein kinase kinase kinase 11 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial Oligophrenin-1 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Phosphatidylinositol 3-kinase regulatory subunit alpha Phospholipase D1 Pleckstrin homology domain-containing family G member 3 Protein ERGIC-53 Protein diaphanous homolog 3 Proto-oncogene DBL Proto-oncogene vav Ragulator complex protein LAMTOR1 Ras GTPase-activating-like protein IQGAP2 Ras-related protein Rab-7a Rho GDP-dissociation inhibitor 1 Rho GDP-dissociation inhibitor 2 Rho GDP-dissociation inhibitor 3 Rho GTPase-activating protein 1 Rho GTPase-activating protein 21 Rho GTPase-activating protein 32 Rho GTPase-activating protein 35 Rho GTPase-activating protein 39 Rho GTPase-activating protein 5 Rho guanine nucleotide exchange factor 16 Rho guanine nucleotide exchange factor 26 Rho guanine nucleotide exchange factor 5 Rho-related GTP-binding protein RhoG Serine hydroxymethyltransferase, mitochondrial Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 4 Serine/threonine-protein kinase VRK2 Starch-binding domain-containing protein 1 Synaptobrevin homolog YKT6 Syntaxin-5 Transferrin receptor protein 1 Triple functional domain protein Vang-like protein 1 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein-associated protein B/C	A1L390 A7KAX9 O15063 O15068 O15173 O15498 O60229 O60890 O75489 O75962 O95202 O95210 O95292 O96013 P02786 P05556 P10911 P15498 P27986 P29317 P34897 P42167 P43121 P49257 P50402 P51149 P52565 P52566 P52735 P60953 P61604 P84095 Q00587 Q03135 Q07960 Q12774 Q13017 Q13177 Q13190 Q13393 Q13576 Q14126 Q14185 Q14739 Q15811 Q15836 Q16584 Q16718 Q5T2T1 Q5T5U3 Q5VV41 Q6IAA8 Q7L576 Q86UP2 Q86XL3 Q86Y07 Q8IZD9 Q8N1I0 Q8TAA9 Q8TCU6 Q8WUY9 Q92608 Q96DR7 Q96JJ3 Q96RT1 Q99819 Q9BSJ8 Q9C0H5 Q9H7D0 Q9NP61 Q9NRY4 Q9NSV4 Q9UKW4 Q9Y2U8	ANKLE2 ARFGAP1 ARFGAP3 ARHG ARHGAP1 ARHGAP10 ARHGAP21 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP5 ARHGDIA ARHGDIB ARHGDIG ARHGEF16 ARHGEF26 ARHGEF5 BORG5 C11orf59 CAV CAV1 CDC42 CDC42EP1 CDC42GAP CDHF5 CED12A CEP1 CG1 CYFIP1 DBL DEPDC1B DG6 DIAP3 DIAPH3 DOCK1 DOCK2 DOCK3 DOCK4 DOCK5 DSG2 DUET DUO ECK EDMD ELMO2 EMD EPHA2 EPHEXIN4 ERBB2IP ERBIN ERGIC53 ESYT1 F5F8D FAM62A FNRB GARRE1 GDIA1 GDIA2 GDID4 GRB1 GRF1 GRIT GRLF1 HAPIP HSPE1 IQGAP2 ITGB1 ITSN ITSN1 KALRN KIAA0004 KIAA0068 KIAA0209 KIAA0299 KIAA0355 KIAA0362 KIAA0599 KIAA0692 KIAA0712 KIAA0716 KIAA0747 KIAA1142 KIAA1225 KIAA1415 KIAA1424 KIAA1688 KIAA1722 KIAA1834 KTN1 LAMTOR1 LAP2 LBR LEM4 LEMD3 LETM1 LMAN1 MAN1 MAP3K11 MBC2 MCAM MCF2 MCF2L MDF2 MLK3 MOCA MPP7 MSE55 MSK12 MUC18 NBR NDUFA5 NDUFS3 OPHN1 OST P190A PAK2 PAK4 PDRO PGRMC2 PIK3R1 PLD1 PLEKHG3 PMBP PREX1 PTK1 RAB7 RAB7A RAP1GN1 RHOG RHOGAP1 RHOGAP5 RICS SGEF SH3D1A SHMT2 SPRK STA STB2 STBD1 STX5 STX5A SYB3 TFRC TIM TMPO TRAD TRIO VAMP3 VANGL1 VAPB VAV VAV1 VAV2 VAV3 VRK2 XTP8 YKT6 p190ARHOGAP
Glucocorticoid biosynthesis	11-beta-hydroxysteroid dehydrogenase 1 11-beta-hydroxysteroid dehydrogenase type 2 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 Corticosteroid-binding globulin Cytochrome P450 11B1, mitochondrial Cytochrome P450 11B2, mitochondrial Pro-opiomelanocortin Steroid 17-alpha-hydroxylase/17,20 lyase Steroid 21-hydroxylase	P01189 P05093 P08185 P08686 P14060 P15538 P19099 P26439 P28845 P80365	3BH CBG CYP11B1 CYP11B2 CYP17 CYP17A1 CYP21 CYP21A2 CYP21B HSD11 HSD11B1 HSD11B2 HSD11K HSD11L HSD3B1 HSD3B2 HSDB3A HSDB3B POMC S11BH S17AH SDR26C1 SDR9C3 SERPINA6
Prednisone ADME	11-beta-hydroxysteroid dehydrogenase 1 11-beta-hydroxysteroid dehydrogenase type 2 ATP-dependent translocase ABCB1 Albumin Aldo-keto reductase family 1 member C1 Corticosteroid-binding globulin Cytochrome P450 3A4 UDP-glucuronosyltransferase 1A3 UDP-glucuronosyltransferase 2B17 UDP-glucuronosyltransferase 2B7	O75795 P02768 P08183 P08185 P08684 P16662 P28845 P35503 P80365 Q04828	ABCB1 AKR1C1 ALB CBG CYP3A3 CYP3A4 DDH DDH1 GNT1 HSD11 HSD11B1 HSD11B2 HSD11K HSD11L MDR1 PGY1 SDR26C1 SDR9C3 SERPINA6 UGT1 UGT1A3 UGT2B17 UGT2B7 UGTB2B9
pre-mRNA splicing	116 kDa U5 small nuclear ribonucleoprotein component 17S U2 SnRNP complex component HTATSF1 ATP-dependent RNA helicase A ATP-dependent RNA helicase DDX42 ATP-dependent RNA helicase DHX15 ATP-dependent RNA helicase DHX8 Apoptotic chromatin condensation inducer in the nucleus BUD13 homolog Beta-catenin-like protein 1 CWF19-like protein 2 Calcium homeostasis endoplasmic reticulum protein Cell division cycle 5-like protein Cell division cycle and apoptosis regulator protein 1 Coiled-coil domain-containing protein 12 Crooked neck-like protein 1 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 DnaJ homolog subfamily C member 8 E3 ubiquitin-protein ligase RNF113A Eukaryotic initiation factor 4A-III Exosome RNA helicase MTR4 G patch domain-containing protein 1 G-patch domain and KOW motifs-containing protein General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Heat shock cognate 71 kDa protein Heterogeneous nuclear ribonucleoprotein A1 Heterogeneous nuclear ribonucleoprotein A3 Heterogeneous nuclear ribonucleoprotein D0 Heterogeneous nuclear ribonucleoprotein F Heterogeneous nuclear ribonucleoprotein H2 Heterogeneous nuclear ribonucleoprotein H Heterogeneous nuclear ribonucleoprotein K Heterogeneous nuclear ribonucleoprotein L Heterogeneous nuclear ribonucleoprotein M Heterogeneous nuclear ribonucleoprotein R Heterogeneous nuclear ribonucleoprotein U Heterogeneous nuclear ribonucleoproteins A2/B1 Heterogeneous nuclear ribonucleoproteins C1/C2 Histone deacetylase complex subunit SAP18 Intron Large complex component GCFC2 Leukocyte receptor cluster member 1 Luc7-like protein 3 Microfibrillar-associated protein 1 NF-kappa-B-activating protein NHP2-like protein 1 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Nuclear inhibitor of protein phosphatase 1 Nuclear speckle splicing regulatory protein 1 PHD finger-like domain-containing protein 5A PRKR-interacting protein 1 Peptidyl-prolyl cis-trans isomerase E Peptidyl-prolyl cis-trans isomerase G Peptidyl-prolyl cis-trans isomerase H Peptidyl-prolyl cis-trans isomerase-like 1 Peptidyl-prolyl cis-trans isomerase-like 3 Peptidyl-prolyl cis-trans isomerase-like 4 Peptidylprolyl isomerase domain and WD repeat-containing protein 1 Pinin Pleiotropic regulator 1 Poly(U)-binding-splicing factor PUF60 Poly(rC)-binding protein 1 Poly(rC)-binding protein 2 Polyglutamine-binding protein 1 Polypyrimidine tract-binding protein 1 Pre-mRNA-processing factor 17 Pre-mRNA-processing factor 19 Pre-mRNA-processing factor 40 homolog A Pre-mRNA-processing factor 6 Pre-mRNA-processing-splicing factor 8 Pre-mRNA-splicing factor 18 Pre-mRNA-splicing factor 38A Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 Pre-mRNA-splicing factor CWC22 homolog Pre-mRNA-splicing factor CWC25 homolog Pre-mRNA-splicing factor ISY1 homolog Pre-mRNA-splicing factor RBM22 Pre-mRNA-splicing factor SLU7 Pre-mRNA-splicing factor SPF27 Pre-mRNA-splicing factor SYF1 Pre-mRNA-splicing factor SYF2 Probable ATP-dependent RNA helicase DDX23 Probable ATP-dependent RNA helicase DDX41 Probable ATP-dependent RNA helicase DDX46 Probable ATP-dependent RNA helicase DDX5 Probable ATP-dependent RNA helicase DHX35 Proline-rich protein PRCC Protein BUD31 homolog Protein CASC3 Protein FAM32A Protein FAM50A Protein Red Protein mago nashi homolog 2 Protein mago nashi homolog RING-type E3 ubiquitin-protein ligase PPIL2 RNA helicase aquarius RNA-binding motif protein, X chromosome RNA-binding motif protein, X-linked 2 RNA-binding protein 10 RNA-binding protein 25 RNA-binding protein 39 RNA-binding protein 42 RNA-binding protein 5 RNA-binding protein 7 RNA-binding protein 8A RNA-binding protein FUS RNA-binding protein with serine-rich domain 1 Regulator of nonsense transcripts 3B SNW domain-containing protein 1 STING ER exit protein SURP and G-patch domain-containing protein 1 Serine/arginine repetitive matrix protein 1 Serine/arginine repetitive matrix protein 2 Serine/arginine-rich splicing factor 10 Serine/arginine-rich splicing factor 11 Serine/arginine-rich splicing factor 12 Serine/arginine-rich splicing factor 1 Serine/arginine-rich splicing factor 2 Serine/arginine-rich splicing factor 3 Serine/arginine-rich splicing factor 4 Serine/arginine-rich splicing factor 5 Serine/arginine-rich splicing factor 6 Serine/arginine-rich splicing factor 7 Serine/arginine-rich splicing factor 8 Serine/arginine-rich splicing factor 9 Serine/threonine-protein kinase PRP4 homolog Serrate RNA effector molecule homolog Smad nuclear-interacting protein 1 Small nuclear ribonucleoprotein E Small nuclear ribonucleoprotein F Small nuclear ribonucleoprotein G Small nuclear ribonucleoprotein Sm D1 Small nuclear ribonucleoprotein Sm D2 Small nuclear ribonucleoprotein Sm D3 Small nuclear ribonucleoprotein-associated protein N Small nuclear ribonucleoprotein-associated proteins B and B' Spliceosome RNA helicase DDX39B Spliceosome-associated protein CWC15 homolog Spliceosome-associated protein CWC27 homolog Splicing factor 1 Splicing factor 3A subunit 1 Splicing factor 3A subunit 2 Splicing factor 3A subunit 3 Splicing factor 3B subunit 1 Splicing factor 3B subunit 2 Splicing factor 3B subunit 3 Splicing factor 3B subunit 4 Splicing factor 3B subunit 5 Splicing factor 3B subunit 6 Splicing factor 45 Splicing factor C9orf78 Splicing factor Cactin Splicing factor U2AF 26 kDa subunit Splicing factor U2AF 35 kDa subunit Splicing factor U2AF 65 kDa subunit Splicing factor YJU2 Splicing regulator SDE2 Survival of motor neuron-related-splicing factor 30 THO complex subunit 4 Thioredoxin-like protein 4A Transcription elongation regulator 1 Transformer-2 protein homolog beta Tuftelin-interacting protein 11 U1 small nuclear ribonucleoprotein 70 kDa U1 small nuclear ribonucleoprotein A U1 small nuclear ribonucleoprotein C U2 small nuclear ribonucleoprotein A' U2 small nuclear ribonucleoprotein B'' U2 snRNP-associated SURP motif-containing protein U4/U6 small nuclear ribonucleoprotein Prp31 U4/U6 small nuclear ribonucleoprotein Prp3 U4/U6 small nuclear ribonucleoprotein Prp4 U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein U4/U6.U5 tri-snRNP-associated protein 1 U5 small nuclear ribonucleoprotein 200 kDa helicase U5 small nuclear ribonucleoprotein 40 kDa protein U6 snRNA-associated Sm-like protein LSm2 U6 snRNA-associated Sm-like protein LSm3 U6 snRNA-associated Sm-like protein LSm4 U6 snRNA-associated Sm-like protein LSm5 U6 snRNA-associated Sm-like protein LSm6 U6 snRNA-associated Sm-like protein LSm7 U6 snRNA-associated Sm-like protein LSm8 Ubiquitin carboxyl-terminal hydrolase 39 Ubiquitin-like protein 5 WD repeat-containing protein 70 WD40 repeat-containing protein SMU1 WW domain-binding protein 11 WW domain-binding protein 4 Y-box-binding protein 1 Zinc finger matrin-type protein 2 Zinc finger protein 830	O00422 O14776 O15042 O15234 O15514 O15541 O43143 O43172 O43290 O43390 O43395 O43447 O43660 O43719 O60231 O60306 O60508 O60828 O75400 O75494 O75533 O75554 O75643 O75934 O75937 O75940 O94906 O95232 O95391 O95777 O95926 P07910 P08579 P08621 P09012 P09234 P09651 P09661 P11142 P13984 P14678 P14866 P16383 P17844 P19387 P19388 P22626 P24928 P26368 P26599 P30876 P31943 P35269 P35637 P36954 P38159 P38919 P41223 P42285 P49756 P51991 P52272 P52298 P52434 P52435 P52597 P52756 P53803 P55081 P55769 P55795 P61218 P61326 P61978 P62304 P62306 P62308 P62310 P62312 P62314 P62316 P62318 P62487 P62875 P62995 P63162 P67809 P83876 P84103 P98175 Q00839 Q01081 Q01130 Q05519 Q07955 Q08170 Q08211 Q09161 Q12874 Q12972 Q13123 Q13242 Q13243 Q13247 Q13356 Q13427 Q13435 Q13523 Q13573 Q13838 Q14103 Q14320 Q14498 Q14562 Q15029 Q15287 Q15365 Q15366 Q15393 Q15427 Q15428 Q15459 Q15637 Q16629 Q2TAY7 Q2TBE0 Q53GS9 Q6IQ49 Q6P2Q9 Q6UX04 Q7L014 Q7RTV0 Q86V81 Q86XP3 Q8IWX8 Q8IWZ8 Q8IX12 Q8IYB3 Q8N5F7 Q8NAV1 Q8TAD8 Q8WU68 Q8WUA2 Q8WUD4 Q8WUQ7 Q8WVK2 Q8WWY3 Q8WXF0 Q8WYA6 Q92620 Q92733 Q92917 Q96A72 Q96BP3 Q96BZ8 Q96DI7 Q96I25 Q96NB3 Q96NC0 Q99459 Q99633 Q9BRD0 Q9BRL6 Q9BRR8 Q9BTD8 Q9BUQ8 Q9BW85 Q9BWJ5 Q9BXP5 Q9BZI7 Q9BZJ0 Q9BZL1 Q9H0G5 Q9H2H8 Q9H307 Q9H5V9 Q9H5Z1 Q9H875 Q9HCG8 Q9HCS7 Q9NW64 Q9NW82 Q9NXE8 Q9NZ63 Q9P013 Q9UBB9 Q9UHX1 Q9UJV9 Q9UK45 Q9UKV3 Q9ULR0 Q9UMS4 Q9UNP9 Q9UQ35 Q9Y2W2 Q9Y333 Q9Y388 Q9Y3B4 Q9Y3C6 Q9Y421 Q9Y4Y9 Q9Y4Z0 Q9Y580 Q9Y5S9	ABS ACIN1 ACINUS ALY ALYREF AQR ARD1 ARS2 ASCC3L1 ASF ASR2 AUF1 BAT1 BCAS2 BEF BRR2 BUD13 BUD31 C11orf5 C19orf29 C1orf199 C1orf55 C20orf14 C20orf15 C20orf33 C2orf3 C6orf28 C9orf78 CA150 CACTIN CARP1 CASC3 CBP20 CBP80 CBPIN CCAR1 CCDC12 CCDC16 CCDC49 CCDC55 CCDC94 CDC40 CDC5L CHERP COD CREAP1 CRN CRNKL1 CROP CTNNBL1 CWC15 CWC22 CWC25 CWC27 CWF19L2 CXorf56 CYP20 CYP33 CYPH CYPL1 DAM1 DAN26 DBP1 DBP2 DDX15 DDX16 DDX23 DDX35 DDX38 DDX39B DDX41 DDX42 DDX46 DDX48 DDX5 DDX8 DDX9 DHX15 DHX16 DHX35 DHX38 DHX8 DHX9 DIM1 DIS DNAJC8 DOB1 DRS DXS8237E DXS9928E ECGP EDG2 EFTUD2 EHB3 EIF4A3 FAM32A FAM50A FBP11 FBP21 FIR FLAF1 FNBP21 FNBP3 FTP3 FUS FUSIP1 FUSIP2 G17P1 G7B GCF GCFC2 GCIPIP GPATC1 GPATC5 GPATC9 GPATCH1 GPATCH5 GPATCH9 GPKOW GTF2F1 GTF2F2 HCA59 HCC1 HCERN3 HCNP HELIC2 HELR HIP10 HLR1 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPC HNRNPD HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPL HNRNPM HNRNPR HNRNPU HNRPA1 HNRPA2B1 HNRPA3 HNRPC HNRPD HNRPF HNRPG HNRPH HNRPH1 HNRPH2 HNRPK HNRPL HNRPM HNRPR HNRPU HPRP18 HPRP3 HRS HSC70 HSP73 HSPA10 HSPA8 HTATSF1 HXC26 HYPA IK ISY1 KIAA0017 KIAA0031 KIAA0052 KIAA0073 KIAA0111 KIAA0122 KIAA0224 KIAA0324 KIAA0332 KIAA0432 KIAA0536 KIAA0560 KIAA0577 KIAA0670 KIAA0788 KIAA0801 KIAA1160 KIAA1177 KIAA1604 LDC2 LENG1 LKP LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 LSM8 LUC7L3 MAGOH MAGOH2 MAGOHA MAGOHB MEMA MFAP1 MLN51 MTR4 MTREX NAGR1 NCBP NCBP1 NCBP2 NCM NDH2 NHP2L1 NIPP1 NKAP NMP200 NPW38 NPWBP NSEP1 NSRP1 NSRP70 O48 OTAG12 PBSCF PBSCG PCBP1 PCBP2 PCDC5RP PHF5A PLRG1 PNN POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF PPIE PPIG PPIH PPIL1 PPIL2 PPIL3 PPIL4 PPP1R8 PPWD1 PQBP1 PRCC PRKRIP1 PRP16 PRP17 PRP19 PRP2 PRP3 PRP31 PRP4 PRP4B PRP4H PRP4K PRP8BP PRPC8 PRPF17 PRPF18 PRPF19 PRPF3 PRPF31 PRPF38A PRPF4 PRPF40A PRPF4K PRPF6 PRPF8 PTB PTBP1 PUF60 RAP30 RAP74 RBM10 RBM17 RBM22 RBM25 RBM39 RBM42 RBM5 RBM7 RBM8 RBM8A RBMX RBMX2 RBMXP1 RED RENT3B RER RNF113 RNF113A RNPC2 RNPC7 RNPS1 RNPU1Z ROBPI RPB7 RPU1 SAFA SAP114 SAP130 SAP14 SAP145 SAP155 SAP18 SAP49 SAP61 SAP62 SART1 SCAF6 SDCCAG10 SDE2 SF1 SF2 SF2P33 SF3A1 SF3A2 SF3A3 SF3B1 SF3B10 SF3B14 SF3B14A SF3B2 SF3B3 SF3B4 SF3B5 SF3B6 SF4 SFP38 SFRS1 SFRS10 SFRS11 SFRS13A SFRS13B SFRS19 SFRS2 SFRS2B SFRS3 SFRS4 SFRS5 SFRS6 SFRS7 SFRS9 SIAHBP1 SIPP1 SKIIP SKIP SKIV2L2 SLU7 SMN SMNDC1 SMNR SMU1 SNEV SNIP1 SNP70 SNRNP200 SNRNP27 SNRNP40 SNRNP70 SNRP116 SNRP70 SNRPA SNRPA1 SNRPB SNRPB1 SNRPB2 SNRPC SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SNRPN SNU13 SNW1 SPF30 SPF31 SPF45 SR140 SRL300 SRM160 SRM300 SRP20 SRP30C SRP40 SRP46 SRP55 SRP75 SRRM1 SRRM2 SRRP35 SRRT SRSF1 SRSF10 SRSF11 SRSF12 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 SRSF9 STEEP1 STIP SUGP1 SYF1 SYF2 T54 TAF2S TASR TCERG1 TCF9 TFIP11 THOC4 TLS TPRC TRA2B TXNL4 TXNL4A U1AP1 U21.1 U2AF1 U2AF1-RS3 U2AF1L3 U2AF1L4 U2AF2 U2AF35 U2AF65 U2AFBP U2SURP UAP56 UBL5 UPF3B UPF3X USP39 WBP11 WBP4 WDR57 WDR70 XAB2 XAP5 YB1 YBX1 YJU2 ZC3H16 ZFM1 ZMAT2 ZNF162 ZNF183 ZNF830
U12 Dependent Splicing	116 kDa U5 small nuclear ribonucleoprotein component ATP-dependent RNA helicase DDX42 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Pre-mRNA-processing factor 6 Pre-mRNA-processing-splicing factor 8 Probable ATP-dependent RNA helicase DDX23 Programmed cell death protein 7 RNA-binding region-containing protein 3 Serine/arginine-rich splicing factor 1 Serine/arginine-rich splicing factor 2 Serine/arginine-rich splicing factor 6 Serine/arginine-rich splicing factor 7 Small nuclear ribonucleoprotein E Small nuclear ribonucleoprotein F Small nuclear ribonucleoprotein G Small nuclear ribonucleoprotein Sm D1 Small nuclear ribonucleoprotein Sm D2 Small nuclear ribonucleoprotein Sm D3 Small nuclear ribonucleoprotein-associated proteins B and B' Splicing factor 3B subunit 1 Splicing factor 3B subunit 2 Splicing factor 3B subunit 3 Splicing factor 3B subunit 4 Splicing factor 3B subunit 5 Splicing factor 3B subunit 6 Thioredoxin-like protein 4A U11/U12 small nuclear ribonucleoprotein 25 kDa protein U11/U12 small nuclear ribonucleoprotein 35 kDa protein U11/U12 small nuclear ribonucleoprotein 48 kDa protein U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 U5 small nuclear ribonucleoprotein 200 kDa helicase U5 small nuclear ribonucleoprotein 40 kDa protein Y-box-binding protein 1 Zinc finger CCHC-type and RNA-binding motif-containing protein 1 Zinc finger matrin-type protein 5	O15514 O75533 O75643 O94906 P13984 P14678 P19387 P19388 P24928 P30876 P35269 P36954 P52298 P52434 P52435 P53803 P61218 P62304 P62306 P62308 P62314 P62316 P62318 P62487 P62875 P67809 P83876 Q01130 Q07955 Q09161 Q13247 Q13435 Q15029 Q15393 Q15427 Q15696 Q16560 Q16629 Q6IEG0 Q6P2Q9 Q86XP3 Q8N8D1 Q8TBF4 Q96DI7 Q96LT9 Q9BUQ8 Q9BV90 Q9BWJ5 Q9UDW3 Q9Y3B4	ASCC3L1 ASF BRR2 C16orf33 C20orf14 C6orf151 CBP20 CBP80 COD DDX23 DDX42 DIM1 EFTUD2 GTF2F1 GTF2F2 HELIC2 HM1 KIAA0017 KIAA0031 KIAA0788 KIAA1839 NCBP NCBP1 NCBP2 NSEP1 PBSCF PBSCG PDCD7 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF PRP8BP PRPC8 PRPF6 PRPF8 RAP30 RAP74 RBM40 RNP RNPC3 RPB7 SAP130 SAP14 SAP145 SAP155 SAP49 SF2 SF2P33 SF3B1 SF3B10 SF3B14 SF3B14A SF3B2 SF3B3 SF3B4 SF3B5 SF3B6 SFP38 SFRS1 SFRS2 SFRS6 SFRS7 SNRNP200 SNRNP25 SNRNP35 SNRNP40 SNRNP48 SNRNP65 SNRP116 SNRPB SNRPB1 SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SRP55 SRSF1 SRSF2 SRSF6 SRSF7 TXNL4 TXNL4A U1SNRNPBP U2AF1-RS2 U2AF1L2 U2AF1RS2 URP WDR57 YB1 YBX1 ZCRB1 ZMAT5 ZRSR2
G alpha (i) signalling events	12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor 2-oxoglutarate receptor 1 5-hydroxytryptamine receptor 1B 5-hydroxytryptamine receptor 1D 5-hydroxytryptamine receptor 1E 5-hydroxytryptamine receptor 1F 5-hydroxytryptamine receptor 5A Adenosine receptor A1 Adenosine receptor A3 Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor Amyloid-beta precursor protein Angiotensinogen Annexin A1 Apelin receptor Apelin Atypical chemokine receptor 3 B1 bradykinin receptor B2 bradykinin receptor C-C chemokine receptor type 10 C-C chemokine receptor type 1 C-C chemokine receptor type 2 C-C chemokine receptor type 3 C-C chemokine receptor type 4 C-C chemokine receptor type 5 C-C chemokine receptor type 6 C-C chemokine receptor type 7 C-C chemokine receptor type 8 C-C chemokine receptor type 9 C-C motif chemokine 13 C-C motif chemokine 16 C-C motif chemokine 19 C-C motif chemokine 1 C-C motif chemokine 20 C-C motif chemokine 21 C-C motif chemokine 25 C-C motif chemokine 27 C-C motif chemokine 28 C-C motif chemokine 4-like C-C motif chemokine 4 C-C motif chemokine 5 C-X-C chemokine receptor type 1 C-X-C chemokine receptor type 2 C-X-C chemokine receptor type 3 C-X-C chemokine receptor type 4 C-X-C chemokine receptor type 5 C-X-C chemokine receptor type 6 C-X-C motif chemokine 10 C-X-C motif chemokine 11 C-X-C motif chemokine 13 C-X-C motif chemokine 16 C-X-C motif chemokine 2 C-X-C motif chemokine 3 C-X-C motif chemokine 5 C-X-C motif chemokine 6 C-X-C motif chemokine 9 C3a anaphylatoxin chemotactic receptor C5a anaphylatoxin chemotactic receptor 1 CX3C chemokine receptor 1 Cannabinoid receptor 1 Cannabinoid receptor 2 Complement C3 Complement C5 Cortistatin D(3) dopamine receptor D(4) dopamine receptor Delta-type opioid receptor Extracellular calcium-sensing receptor Fractalkine G-protein coupled estrogen receptor 1 G-protein coupled receptor 183 G-protein coupled receptor 37-like 1 G-protein coupled receptor 55 G-protein-signaling modulator 1 G-protein-signaling modulator 2 G-protein-signaling modulator 3 Galanin peptides Galanin receptor type 1 Galanin receptor type 2 Galanin receptor type 3 Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2 Growth-regulated alpha protein Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein G(t) subunit alpha-1 Guanine nucleotide-binding protein G(t) subunit alpha-2 Guanine nucleotide-binding protein G(t) subunit alpha-3 Guanine nucleotide-binding protein G(z) subunit alpha Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Heme-binding protein 1 Histamine H4 receptor Humanin Hydroxycarboxylic acid receptor 1 Hydroxycarboxylic acid receptor 2 Hydroxycarboxylic acid receptor 3 Insulin-like peptide INSL5 Interleukin-8 Kappa-type opioid receptor Kininogen-1 Long-wave-sensitive opsin 1 Lysophosphatidic acid receptor 1 Lysophosphatidic acid receptor 2 Lysophosphatidic acid receptor 3 Lysophosphatidic acid receptor 5 Medium-wave-sensitive opsin 1 Melanin-concentrating hormone receptor 1 Melanin-concentrating hormone receptor 2 Melatonin receptor type 1A Melatonin receptor type 1B Metabotropic glutamate receptor 2 Metabotropic glutamate receptor 3 Metabotropic glutamate receptor 4 Metabotropic glutamate receptor 6 Metabotropic glutamate receptor 7 Metabotropic glutamate receptor 8 Mu-type opioid receptor Muscarinic acetylcholine receptor M2 Muscarinic acetylcholine receptor M4 N-arachidonyl glycine receptor N-formyl peptide receptor 2 N-formyl peptide receptor 3 Neuromedin-S Neuromedin-U receptor 1 Neuromedin-U receptor 2 Neuromedin-U Neuropeptide B Neuropeptide W Neuropeptide Y receptor type 1 Neuropeptide Y receptor type 2 Neuropeptide Y receptor type 4 Neuropeptide Y receptor type 5 Neuropeptides B/W receptor type 1 Neuropeptides B/W receptor type 2 Nociceptin receptor Opsin-3 Opsin-5 Oxoeicosanoid receptor 1 P2Y purinoceptor 12 P2Y purinoceptor 13 P2Y purinoceptor 14 P2Y purinoceptor 4 Pancreatic polypeptide prohormone Peptide YY Platelet basic protein Platelet factor 4 Prepronociceptin Pro-MCH Pro-neuropeptide Y Pro-opiomelanocortin Proenkephalin-A Proenkephalin-B Prosaposin receptor GPR37 Prosaposin Prostaglandin D2 receptor 2 Prostaglandin E2 receptor EP3 subtype Proto-oncogene tyrosine-protein kinase Src Purkinje cell protein 2 homolog RPE-retinal G protein-coupled receptor Regulator of G-protein signaling 10 Regulator of G-protein signaling 11 Regulator of G-protein signaling 12 Regulator of G-protein signaling 13 Regulator of G-protein signaling 14 Regulator of G-protein signaling 16 Regulator of G-protein signaling 17 Regulator of G-protein signaling 18 Regulator of G-protein signaling 19 Regulator of G-protein signaling 1 Regulator of G-protein signaling 20 Regulator of G-protein signaling 21 Regulator of G-protein signaling 22 Regulator of G-protein signaling 3 Regulator of G-protein signaling 4 Regulator of G-protein signaling 5 Regulator of G-protein signaling 6 Regulator of G-protein signaling 7 Regulator of G-protein signaling 8 Regulator of G-protein signaling 9 Regulator of G-protein signaling protein-like Relaxin-3 receptor 1 Relaxin-3 receptor 2 Relaxin-3 Rhodopsin Serum amyloid A-1 protein Short-wave-sensitive opsin 1 Somatostatin receptor type 1 Somatostatin receptor type 2 Somatostatin receptor type 3 Somatostatin receptor type 4 Somatostatin receptor type 5 Somatostatin Sphingosine 1-phosphate receptor 2 Sphingosine 1-phosphate receptor 3 Sphingosine 1-phosphate receptor 4 Sphingosine 1-phosphate receptor 5 Stromal cell-derived factor 1 Succinate receptor 1 Taste receptor type 1 member 1 Taste receptor type 1 member 2 Taste receptor type 1 member 3 Taste receptor type 2 member 10 Taste receptor type 2 member 13 Taste receptor type 2 member 14 Taste receptor type 2 member 16 Taste receptor type 2 member 19 Taste receptor type 2 member 1 Taste receptor type 2 member 20 Taste receptor type 2 member 30 Taste receptor type 2 member 31 Taste receptor type 2 member 38 Taste receptor type 2 member 39 Taste receptor type 2 member 3 Taste receptor type 2 member 40 Taste receptor type 2 member 41 Taste receptor type 2 member 42 Taste receptor type 2 member 43 Taste receptor type 2 member 45 Taste receptor type 2 member 46 Taste receptor type 2 member 4 Taste receptor type 2 member 50 Taste receptor type 2 member 5 Taste receptor type 2 member 60 Taste receptor type 2 member 7 Taste receptor type 2 member 8 Taste receptor type 2 member 9 Type-2 angiotensin II receptor Uracil nucleotide/cysteinyl leukotriene receptor Visual pigment-like receptor peropsin fMet-Leu-Phe receptor	A5PLK6 A8MTJ3 O00222 O00230 O00270 O00574 O00585 O14610 O14625 O14718 O14775 O14921 O14924 O15303 O15354 O15444 O15467 O15492 O15539 O43306 O43566 O43603 O43665 O43927 O60262 O60266 O60503 O60755 O60883 O75899 O75916 O76081 O94810 O95136 O95622 O95977 P01019 P01024 P01031 P01042 P01189 P01210 P01213 P01298 P01303 P02775 P02776 P02778 P03999 P04000 P04001 P04083 P04899 P05067 P07602 P08100 P08172 P08173 P08754 P08913 P09341 P0DJI8 P0DMS8 P10082 P10145 P11488 P12931 P13236 P13501 P16520 P18089 P18825 P19086 P19087 P19875 P19876 P20382 P21462 P21554 P21730 P21917 P22362 P22466 P25024 P25025 P25089 P25090 P25106 P25929 P28221 P28222 P28566 P30411 P30542 P30872 P30874 P30939 P31391 P32246 P32248 P32249 P32302 P32745 P34972 P35346 P35372 P35414 P35462 P40145 P41143 P41145 P41146 P41180 P41597 P42830 P43115 P46092 P46663 P47211 P47804 P47898 P48039 P48061 P48145 P48146 P48645 P49019 P49146 P49238 P49286 P49682 P49758 P49795 P49796 P49798 P49802 P50052 P50150 P50151 P50391 P51582 P51677 P51679 P51681 P51684 P51685 P51686 P51828 P57771 P59533 P59534 P59535 P59536 P59537 P59538 P59539 P59540 P59541 P59542 P59543 P59544 P59551 P59768 P61073 P61278 P61952 P62873 P62879 P63092 P63096 P63211 P63215 P63218 P78423 P78556 P80162 P81274 Q07325 Q08116 Q08462 Q08828 Q13304 Q13519 Q14330 Q14416 Q14831 Q14832 Q14833 Q15391 Q15761 Q16581 Q2M5E4 Q5H8A3 Q5JWF2 Q6U736 Q7RTR8 Q7RTX0 Q7RTX1 Q86YR5 Q8IVA1 Q8IVG9 Q8N729 Q8NE09 Q8NFM4 Q8NG41 Q8NHW4 Q8TDS4 Q8TDS5 Q8TDU9 Q8TE23 Q8WXF3 Q92633 Q969V1 Q96P68 Q99500 Q99527 Q99616 Q99705 Q99731 Q9BPV8 Q9BXA5 Q9BXC0 Q9GZQ4 Q9H1C0 Q9H1Y3 Q9H228 Q9H244 Q9H2A7 Q9H3N8 Q9HAV0 Q9HB89 Q9HBW0 Q9NRJ3 Q9NRV9 Q9NS28 Q9NSD7 Q9NYV7 Q9NYV8 Q9NYV9 Q9NYW0 Q9NYW1 Q9NYW2 Q9NYW3 Q9NYW4 Q9NYW5 Q9NYW6 Q9NYW7 Q9P2W3 Q9UBI6 Q9UBS5 Q9UBY5 Q9UGC6 Q9UK08 Q9ULZ1 Q9Y2T6 Q9Y4H4 Q9Y4X3 Q9Y5Q6 Q9Y5Y4	1R20 A4 ACKR3 AD1 ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADORA1 ADORA3 ADRA2A ADRA2B ADRA2C ADRA2L1 ADRA2L2 ADRA2R ADRA2RL1 ADRA2RL2 ADRAR AGS3 AGS4 AGT AGTR2 AGTRL1 ANX1 ANXA1 APEL APJ APLN APLNR APP AZ3B BCA1 BCP BDK BDKRB1 BDKRB2 BKR2 BL34 BLC BLR1 BONZO BRADYB1 C3 C3AR1 C3R1 C5 C5AR C5AR1 C5R1 C6orf9 C9orf108 C9orf47 CASR CB2A CB2B CCL1 CCL13 CCL16 CCL19 CCL20 CCL21 CCL25 CCL27 CCL28 CCL4 CCL4L CCL4L1 CCL4L2 CCL5 CCR1 CCR10 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CEPR CHRM2 CHRM4 CKRL1 CKRL3 CMK CMKAR1 CMKBR1 CMKBR2 CMKBR3 CMKBR4 CMKBR5 CMKBR6 CMKBR7 CMKBR8 CMKBRL1 CMKBRL2 CMKOR1 CMKR1 CMKRL2 CNR CNR1 CNR2 CORT CPAMD1 CPAMD4 CRTH2 CTAP3 CX3CL1 CX3CR1 CXCL1 CXCL10 CXCL11 CXCL12 CXCL13 CXCL16 CXCL2 CXCL3 CXCL4 CXCL5 CXCL6 CXCL7 CXCL8 CXCL9 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 D17S136E DL1R DRD3 DRD4 DRY12 EBI1 EBI2 ECPN EDG2 EDG3 EDG4 EDG5 EDG6 EDG7 EDG8 ELC ENA78 ETBRLP2 EVI1 FKN FPR1 FPR2 FPR3 FPRH1 FPRL1 FPRL2 G18 GABBR1 GABBR2 GAIP GAL GAL1 GALN GALNR GALNR1 GALNR2 GALNR3 GALR1 GALR2 GALR3 GCP GCP2 GLBA GLNN GNAI1 GNAI2 GNAI2B GNAI3 GNAI3IP GNAS GNAS1 GNAT1 GNAT2 GNAT3 GNATC GNATR GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GPCR105 GPCR135 GPCR142 GPCRW GPER GPER1 GPR100 GPR104 GPR105 GPR109A GPR109B GPR13 GPR136 GPR145 GPR159 GPR17 GPR170 GPR18 GPR183 GPR2 GPR24 GPR28 GPR29 GPR30 GPR31 GPR37 GPR37L1 GPR44 GPR51 GPR55 GPR59 GPR60 GPR66 GPR7 GPR70 GPR71 GPR8 GPR80 GPR81 GPR86 GPR9 GPR91 GPR92 GPR93 GPR94 GPR99 GPRC1B GPRC1C GPRC1D GPRC1F GPRC1G GPRC1H GPRC2A GPRC3A GPRC3B GPSM1 GPSM2 GPSM3 GRM2 GRM3 GRM4 GRM6 GRM7 GRM8 GRO GRO1 GRO2 GRO3 GROA GROB GROG GSP HBP HCA1 HCA2 HCA3 HCAR1 HCAR2 HCAR3 HEBP1 HM74A HM74B HN HNFAG09 HORK3 HRH4 HTR1B HTR1D HTR1DA HTR1DB HTR1E HTR1EL HTR1F HTR5A HTRL IER1 IL8 IL8RA IL8RB ILC ILINCK INP10 INSL5 INSL7 ITAC KIAA0001 KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 KNG KNG1 LAG1 LARC LGN LPA1 LPA2 LPA3 LPAR1 LPAR2 LPAR3 LPAR5 LPC1 LXA4R MCH MCHR1 MCHR2 MCP4 MDR15 MGLUR2 MGLUR3 MGLUR4 MGLUR6 MGLUR7 MGLUR8 MGSA MIG MIP1B MIP2A MIP3A MIP3B MOR1 MT-RNR2 MTNR1A MTNR1B NCC1 NCC4 NIACR1 NIACR2 NMS NMU NMU2R NMUR1 NMUR2 NPB NPBWR1 NPBWR2 NPW NPY NPY1R NPY2R NPY4R NPY5R NPYR NPYR5 NPYY1 NRU NTT OFQ OOR OPN1LW OPN1MW OPN1SW OPN2 OPN3 OPN5 OPRD OPRD1 OPRK OPRK1 OPRL1 OPRM1 ORL1 OXER1 OXGR1 P2RY12 P2RY13 P2RY14 P2RY15 P2RY4 P2Y15 PCAR1 PCP2 PDYN PENK PF4 PGR12 PMCH PNOC PNP POMC PPBP PPL7 PPL8 PPNPB PPNPW PPY PPYR1 PSAP PTC PTGDR2 PTGER3 PYY RCP RDC1 RGR RGS1 RGS10 RGS11 RGS12 RGS13 RGS14 RGS16 RGS17 RGS18 RGS19 RGS20 RGS21 RGS22 RGS3 RGS4 RGS5 RGS6 RGS7 RGS8 RGS9 RGSL RGSL1 RGSL2 RGSR RGSZ1 RGSZ2 RHO RLN3 RLN3R1 RLN3R2 RRH RXFP3 RXFP4 RXN3 S1PR2 S1PR3 S1PR4 S1PR5 SAA1 SALPR SAP1 SCYA1 SCYA13 SCYA16 SCYA19 SCYA20 SCYA21 SCYA25 SCYA27 SCYA28 SCYA4 SCYA4L1 SCYA4L2 SCYA5 SCYAR1 SCYB1 SCYB10 SCYB11 SCYB13 SCYB16 SCYB2 SCYB3 SCYB4 SCYB5 SCYB6 SCYB7 SCYB9 SCYB9B SCYD1 SDF1 SDF1A SDF1B SERPINA8 SLC1 SLT SRC SRC1 SRPSOX SST SSTR1 SSTR2 SSTR3 SSTR4 SSTR5 STRL22 STRL33 SUCNR1 T1R1 T1R2 T1R3 TAS1R1 TAS1R2 TAS1R3 TAS2R1 TAS2R10 TAS2R13 TAS2R14 TAS2R16 TAS2R19 TAS2R20 TAS2R23 TAS2R3 TAS2R30 TAS2R31 TAS2R38 TAS2R39 TAS2R4 TAS2R40 TAS2R41 TAS2R42 TAS2R43 TAS2R44 TAS2R45 TAS2R46 TAS2R47 TAS2R48 TAS2R49 TAS2R5 TAS2R50 TAS2R55 TAS2R60 TAS2R7 TAS2R8 TAS2R9 TECK TG1019 TGB1 TGR1 THBGB1 TMEM13 TR1 TR2 TR3 TYMSTR ZGAP1 ZINS4	G58161NS
Free fatty acid receptors	12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor Free fatty acid receptor 1 Free fatty acid receptor 2 Free fatty acid receptor 3 Free fatty acid receptor 4	O00270 O14842 O14843 O15552 Q5NUL3	FFA2 FFAR1 FFAR2 FFAR3 FFAR4 GPCR43 GPR120 GPR129 GPR31 GPR40 GPR41 GPR43 O3FAR1 PGR4
SARS-CoV-1 targets host intracellular signalling and regulatory pathways	14-3-3 protein beta/alpha 14-3-3 protein epsilon 14-3-3 protein eta 14-3-3 protein gamma 14-3-3 protein sigma 14-3-3 protein theta 14-3-3 protein zeta/delta 26S proteasome regulatory subunit 10B 3-phosphoinositide-dependent protein kinase 1 Caveolin-1 Histone acetyltransferase p300 Membrane protein Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Nucleoprotein ORF3a protein SUMO-conjugating enzyme UBC9 Transcription factor Sp1	O15530 P08047 P27348 P31946 P31947 P59595 P59596 P59632 P61981 P62258 P62333 P63104 P63279 P84022 Q03135 Q04917 Q09472 Q13485	3a CAV CAV1 DPC4 EP300 HME1 M MADH3 MADH4 N P300 PDK1 PDPK1 PSMC6 SFN SMAD3 SMAD4 SP1 SUG2 TSFP1 UBC9 UBCE9 UBE2I YWHA1 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ
SARS-CoV-2 targets host intracellular signalling and regulatory pathways	14-3-3 protein beta/alpha 14-3-3 protein epsilon 14-3-3 protein eta 14-3-3 protein gamma 14-3-3 protein sigma 14-3-3 protein theta 14-3-3 protein zeta/delta 3-phosphoinositide-dependent protein kinase 1 Caveolin-1 Membrane protein Nucleoprotein ORF3a protein RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase	O15530 P0DTC3 P0DTC5 P0DTC9 P27348 P31749 P31751 P31946 P31947 P61981 P62258 P63104 Q03135 Q04917 Q9Y243	3a AKT1 AKT2 AKT3 CAV CAV1 HME1 M N PDK1 PDPK1 PKB PKBG RAC SFN YWHA1 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ
RHO GTPases activate PKNs	14-3-3 protein beta/alpha 14-3-3 protein epsilon 14-3-3 protein eta 14-3-3 protein gamma 14-3-3 protein sigma 14-3-3 protein theta 14-3-3 protein zeta/delta 3-phosphoinositide-dependent protein kinase 1 M-phase inducer phosphatase 3 Myosin light polypeptide 6 Myosin regulatory light chain 12B Myosin regulatory light polypeptide 9 Myosin-10 Myosin-11 Myosin-14 Myosin-9 Protein phosphatase 1 regulatory subunit 12A Protein phosphatase 1 regulatory subunit 12B Protein phosphatase 1 regulatory subunit 14A Ras-related C3 botulinum toxin substrate 1 Rho-related GTP-binding protein RhoB Rho-related GTP-binding protein RhoC Serine/threonine-protein kinase N1 Serine/threonine-protein kinase N2 Serine/threonine-protein kinase N3 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein phosphatase PP1-beta catalytic subunit Transforming protein RhoA	O14950 O14974 O15530 O60237 P08134 P24844 P27348 P30307 P31946 P31947 P35579 P35580 P35749 P60660 P61586 P61981 P62140 P62258 P62745 P63000 P63104 Q04917 Q13153 Q16512 Q16513 Q6P5Z2 Q7Z406 Q96A00	ARH12 ARH6 ARH9 ARHA ARHB ARHC CDC25C CPI17 HME1 KIAA0866 KIAA2034 MBS MLC2 MRLC1 MRLC2 MYH10 MYH11 MYH14 MYH9 MYL12B MYL6 MYL9 MYLC2B MYPT1 MYPT2 MYRL2 PAK1 PDK1 PDPK1 PKN PKN1 PKN2 PKN3 PKNBETA PPP1CB PPP1INL PPP1R12A PPP1R12B PPP1R14A PRK1 PRK2 PRKCL1 PRKCL2 RAC1 RHO12 RHOA RHOB RHOC SFN TC25 YWHA1 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ

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