GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **1976 - 2000** of **2090** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol
Regulation of RUNX2 expression and activity	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Bone morphogenetic protein 2 Core-binding factor subunit beta Cullin-1 E3 ubiquitin-protein ligase CHIP E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase SMURF1 Estrogen receptor Glucocorticoid receptor Glycogen synthase kinase-3 beta Homeobox protein DLX-5 Homeobox protein DLX-6 Homeobox protein MSX-2 Homeobox protein Nkx-3.2 NEDD4-like E3 ubiquitin-protein ligase WWP1 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha Peroxisome proliferator-activated receptor gamma coactivator 1-beta Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 S-phase kinase-associated protein 1 S-phase kinase-associated protein 2 Signal transducer and activator of transcription 1-alpha/beta Steroid hormone receptor ERR1 Transcription factor HIVEP3 Twist-related protein 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O43242 O75832 P03372 P04150 P0CG47 P0CG48 P11474 P12643 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35548 P35998 P40306 P42224 P43686 P48556 P49720 P49721 P49841 P51665 P55036 P56178 P56179 P60896 P60900 P61289 P62191 P62195 P62333 P62877 P62979 P62987 P63208 P78367 Q06323 Q13200 Q13309 Q13616 Q13951 Q14997 Q15008 Q15672 Q16401 Q5T1R4 Q86YN6 Q8TAA3 Q92530 Q99436 Q99460 Q9H0M0 Q9HCE7 Q9UBK2 Q9UL46 Q9UNE7 Q9UNM6	BAPX1 BHLHA38 BMP2 BMP2A C7orf76 CBFB CHIP CUL1 DLX5 DLX6 DSS1 EMC19 ERR1 ESR ESR1 ESRL1 ESRRA FBXL1 GRL GSK3B HC2 HC3 HC8 HC9 HIVEP3 HOX8 HSPC IFI5111 KBP1 KIAA0072 KIAA0077 KIAA0107 KIAA1555 KIAA1625 KRC LEM6 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 MSX2 NKX3-2 NKX3B NR3A1 NR3B1 NR3C1 NU OCP2 PERC PFAAP4 PGC1 PGC1A PGC1B POH1 PPARGC1 PPARGC1A PPARGC1B PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RBX1 RING10 RING12 RNF75 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SKP2 SMURF1 STAT1 STUB1 SUG1 SUG2 TBP1 TBP7 TCEB1L TRAP2 TWIST TWIST1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WWP1 X Y Y2 Z ZAS3
Vpu mediated degradation of CD4	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 F-box/WD repeat-containing protein 1A Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein Vpu S-phase kinase-associated protein 1 T-cell surface glycoprotein CD4 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O43242 O75832 P01730 P05919 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 P63208 Q06323 Q13200 Q14997 Q15008 Q16401 Q8TAA3 Q92530 Q99436 Q99460 Q9UL46 Q9UNM6 Q9Y297	BTRC BTRCP C7orf76 CD4 DSS1 EMC19 FBW1A FBXW1A HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0077 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NU OCP2 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RING10 RING12 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SUG1 SUG2 TBP1 TBP7 TCEB1L TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 Z vpu
The role of GTSE1 in G2/M progression after G2 checkpoint	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cellular tumor antigen p53 Cyclin-dependent kinase 1 Cyclin-dependent kinase inhibitor 1 FK506-binding protein-like G2 and S phase-expressed protein 1 G2/mitotic-specific cyclin-B1 G2/mitotic-specific cyclin-B2 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Microtubule-associated protein RP/EB family member 1 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Serine/threonine-protein kinase PLK1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O43242 O75832 O95067 P04637 P06493 P07900 P08238 P0CG47 P0CG48 P14635 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P38936 P40306 P43686 P48556 P49720 P49721 P51665 P53350 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q06323 Q13200 Q14997 Q15008 Q15691 Q16401 Q8TAA3 Q92530 Q99436 Q99460 Q9NYZ3 Q9UIM3 Q9UL46 Q9UNM6	C7orf76 CAP20 CCNB CCNB1 CCNB2 CDC2 CDC28A CDK1 CDKN1 CDKN1A CIP1 DIR1 DSS1 FKBPL GTSE1 HC2 HC3 HC8 HC9 HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC HSPC1 HSPC2 HSPC3 HSPCA HSPCB IFI5111 KIAA0072 KIAA0077 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY MAPRE1 MB1 MCB1 MDA6 MECL1 MIP224 MOV34L MSS1 NG7 NU P34CDC2 P53 PFAAP4 PIC1 PLK PLK1 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RING10 RING12 RPS27A SDI1 SEM1 SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TP53 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WAF1 X Y Y2 Z
KEAP1-NFE2L2 pathway	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 APC membrane recruitment protein 1 Breast cancer type 1 susceptibility protein Casein kinase II subunit alpha' Casein kinase II subunit alpha Casein kinase II subunit beta Cullin-3 Cyclin-dependent kinase inhibitor 1 Dipeptidyl peptidase 3 E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase TRIM21 Eukaryotic translation initiation factor 2-alpha kinase 3 Kelch-like ECH-associated protein 1 Microtubule-associated proteins 1A/1B light chain 3B Mitochondrial ubiquitin ligase activator of NFKB 1 Nuclear factor erythroid 2-related factor 2 Nuclear protein localization protein 4 homolog Partner and localizer of BRCA2 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein X Protein kinase C delta type Protein kinase C iota type RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Sequestosome-1 Sestrin-1 Sestrin-2 Transitional endoplasmic reticulum ATPase UBX domain-containing protein 7 Ubiquitin recognition factor in ER-associated degradation protein 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O43242 O75832 O94888 P0CG47 P0CG48 P17980 P19474 P19784 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P31749 P31751 P35998 P38398 P38936 P40306 P41743 P43686 P48556 P49720 P49721 P51665 P55036 P55072 P58004 P60896 P60900 P61289 P62191 P62195 P62333 P62877 P62979 P62987 P67870 P68400 Q05655 Q06323 Q13200 Q13501 Q13618 Q14145 Q14997 Q15008 Q16236 Q16401 Q2F514 Q5JTC6 Q86YC2 Q8TAA3 Q8TAT6 Q92530 Q92890 Q969V5 Q99436 Q99460 Q9GZQ8 Q9NY33 Q9NZJ5 Q9UL46 Q9UNM6 Q9Y243 Q9Y6P5	AKT1 AKT2 AKT3 AMER1 BRCA1 C1orf166 C7orf76 CAP20 CDKN1 CDKN1A CIP1 CK2A1 CK2A2 CK2N CSNK2A1 CSNK2A2 CSNK2B CUL3 DPP3 DSS1 DXS1179E EIF2AK3 FAM123B FANCN G5A GIDE HC2 HC3 HC8 HC9 HEL-220 HEL-S-70 HSPC Hi95 IFI5111 INRF2 KEAP1 KIAA0072 KIAA0077 KIAA0107 KIAA0132 KIAA0617 KIAA0794 KIAA1499 KLHL19 LMP10 LMP2 LMP7 LMPX LMPY MAP1ALC3 MAP1LC3B MAPL MB1 MCB1 MDA6 MECL1 MIP224 MOV34L MSS1 MUL1 MULAN NFE2L2 NPL4 NPLOC4 NRF2 NU ORCA OSIL PA26 PALB2 PEK PERK PFAAP4 PIC1 PKB PKBG PKCD POH1 PRKCD PRKCI PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RAC RBX1 RING10 RING12 RNF218 RNF53 RNF75 RNF81 RO52 ROC1 RPS27A SDI1 SEM1 SESN1 SESN2 SEST1 SEST2 SHFDG1 SHFM1 SQSTM1 SSA1 SUG1 SUG2 TBP1 TBP7 TRAP2 TRIM21 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBXD7 UBXN7 UFD1 UFD1L VCP WAF1 WTX X Y Y2 Z x
Defective CFTR causes cystic fibrosis	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cystic fibrosis transmembrane conductance regulator Derlin-1 Derlin-2 Derlin-3 E3 ubiquitin-protein ligase RNF185 E3 ubiquitin-protein ligase RNF5 Endoplasmic reticulum lectin 1 Erlin-1 Erlin-2 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein OS-9 Protein sel-1 homolog 1 Transitional endoplasmic reticulum ATPase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O43242 O75477 O75832 O94905 P0CG47 P0CG48 P13569 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P55072 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q06323 Q13200 Q13438 Q14997 Q15008 Q16401 Q8TAA3 Q92530 Q96DZ1 Q96GF1 Q96Q80 Q99436 Q99460 Q99942 Q9BUN8 Q9GZP9 Q9UBV2 Q9UL46 Q9UNM6	ABCC7 C10orf69 C22orf14 C2orf30 C7orf76 C8orf2 CFTR DER1 DER2 DER3 DERL1 DERL2 DERL3 DSS1 ERLEC1 ERLIN1 ERLIN2 FLANA G16 HC2 HC3 HC8 HC9 HEL-220 HEL-S-70 HSPC IFI5111 KE04 KEO4 KIAA0072 KIAA0077 KIAA0107 LLN2 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NG2 NU OS9 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RING10 RING12 RMA1 RNF185 RNF5 RPS27A SEL1L SEM1 SHFDG1 SHFM1 SPFH1 SPFH2 SUG1 SUG2 TBP1 TBP7 TRAP2 TSA305 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VCP X XTP3TPB Y Y2 Z
Orc1 removal from chromatin	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cell division control protein 6 homolog Cullin-1 Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 DNA helicase MCM8 DNA replication factor Cdt1 DNA replication licensing factor MCM2 DNA replication licensing factor MCM3 DNA replication licensing factor MCM4 DNA replication licensing factor MCM5 DNA replication licensing factor MCM6 DNA replication licensing factor MCM7 E3 ubiquitin-protein ligase RBX1 Origin recognition complex subunit 1 Origin recognition complex subunit 2 Origin recognition complex subunit 3 Origin recognition complex subunit 4 Origin recognition complex subunit 5 Origin recognition complex subunit 6 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 S-phase kinase-associated protein 1 S-phase kinase-associated protein 2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O43242 O43913 O43929 O75832 P0CG47 P0CG48 P17980 P20248 P20618 P24941 P25205 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P33991 P33992 P33993 P35998 P40306 P43686 P48556 P49720 P49721 P49736 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62877 P62979 P62987 P63208 P78396 Q06323 Q13200 Q13309 Q13415 Q13416 Q13616 Q14566 Q14997 Q15008 Q16401 Q8TAA3 Q92530 Q99436 Q99460 Q99741 Q9H211 Q9UBD5 Q9UJA3 Q9UL46 Q9UNM6 Q9Y5N6	BM28 C20orf154 C7orf76 CCN1 CCNA CCNA1 CCNA2 CCNL1 CDC18L CDC21 CDC46 CDC47 CDC6 CDCL1 CDK2 CDKN2 CDT1 CUL1 DSS1 EMC19 FBXL1 HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0030 KIAA0072 KIAA0077 KIAA0107 LATHEO LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MCM8 MECL1 MIP224 MOV34L MSS1 NU OCP2 ORC1 ORC1L ORC2 ORC2L ORC3 ORC3L ORC4 ORC4L ORC5 ORC5L ORC6 ORC6L PARC1 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RBX1 RING10 RING12 RNF75 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SKP2 SUG1 SUG2 TBP1 TBP7 TCEB1L TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 Z
Regulation of RAS by GAPs	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-3 Disabled homolog 2-interacting protein E3 ubiquitin-protein ligase RBX1 GTPase HRas GTPase NRas Kelch repeat and BTB domain-containing protein 7 Neurofibromin Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 RAS protein activator like-3 Ras GTPase-activating protein 1 Ras GTPase-activating protein 2 Ras GTPase-activating protein 3 Ras GTPase-activating protein 4 Ras GTPase-activating protein nGAP Ras/Rap GTPase-activating protein SynGAP RasGAP-activating-like protein 1 Sprouty-related, EVH1 domain-containing protein 1 Sprouty-related, EVH1 domain-containing protein 2 Sprouty-related, EVH1 domain-containing protein 3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O43242 O43374 O75832 O95294 P01111 P01112 P0CG47 P0CG48 P17980 P20618 P20936 P21359 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62877 P62979 P62987 Q06323 Q13200 Q13618 Q14644 Q14997 Q15008 Q15283 Q16401 Q2MJR0 Q5VWQ8 Q7Z698 Q7Z699 Q86YV0 Q8TAA3 Q8WVZ9 Q92530 Q96PV0 Q99436 Q99460 Q9UJF2 Q9UL46 Q9UNM6	AF9Q34 AIP1 C7orf76 CAPRI CUL3 DAB2IP DSS1 EVE-3 GAP GAP1M GAPL HC2 HC3 HC8 HC9 HRAS HRAS1 HSPC IFI5111 KBTBD7 KIAA0072 KIAA0077 KIAA0107 KIAA0538 KIAA0617 KIAA1743 KIAA1938 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NF1 NGAP NRAS NU PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RASA RASA1 RASA2 RASA3 RASA4 RASAL RASAL1 RASAL2 RASAL3 RASGAP RBX1 RING10 RING12 RNF75 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SPRED1 SPRED2 SPRED3 SUG1 SUG2 SYNGAP1 TBP1 TBP7 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 Z
Hedgehog ligand biogenesis	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Derlin-2 Desert hedgehog protein E3 ubiquitin-protein ligase synoviolin Endoplasmic reticulum lectin 1 Indian hedgehog protein Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein OS-9 Protein disulfide-isomerase Protein sel-1 homolog 1 Protein-cysteine N-palmitoyltransferase HHAT Sonic hedgehog protein Transitional endoplasmic reticulum ATPase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O43242 O43323 O75832 P07237 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P55072 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q06323 Q13200 Q13438 Q14623 Q14997 Q15008 Q15465 Q16401 Q5VTY9 Q86TM6 Q8TAA3 Q92530 Q96DZ1 Q99436 Q99460 Q9GZP9 Q9UBV2 Q9UL46 Q9UNM6	C2orf30 C7orf76 DER2 DERL2 DHH DSS1 ERBA2L ERLEC1 FLANA HC2 HC3 HC8 HC9 HEL-220 HEL-S-70 HHAT HRD1 HSPC IFI5111 IHH KIAA0072 KIAA0077 KIAA0107 KIAA1810 LMP10 LMP2 LMP7 LMPX LMPY MART2 MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NU OS9 P4HB PDI PDIA1 PFAAP4 PO4DB POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RING10 RING12 RPS27A SEL1L SEM1 SHFDG1 SHFM1 SHH SKI1 SUG1 SUG2 SYVN1 TBP1 TBP7 TRAP2 TSA305 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VCP X XTP3TPB Y Y2 Z
Hedgehog 'on' state	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cilium assembly protein DZIP1 Cullin-3 Desert hedgehog protein E3 ubiquitin-protein ligase Itchy homolog E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase SMURF1 E3 ubiquitin-protein ligase SMURF2 EvC complex member EVC G-protein coupled receptor 161 Indian hedgehog protein Kinesin-like protein KIF7 Limbin Parafibromin Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein numb homolog Protein patched homolog 1 Protein smoothened Serine/threonine-protein kinase ULK3 Sonic hedgehog protein Speckle-type POZ protein-like Speckle-type POZ protein Suppressor of fused homolog Transcriptional activator GLI3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Zinc finger protein GLI1 Zinc finger protein GLI2	A5LHX3 O00231 O00232 O00233 O00487 O14818 O43242 O43323 O43791 O75832 P08151 P0CG47 P0CG48 P10070 P10071 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P49757 P51665 P55036 P57679 P60896 P60900 P61289 P62191 P62195 P62333 P62877 P62979 P62987 Q06323 Q13200 Q13618 Q13635 Q14623 Q14997 Q15008 Q15465 Q16401 Q2M1P5 Q6IQ16 Q6P1J9 Q6PHR2 Q86UK5 Q86YF9 Q8N6U8 Q8TAA3 Q92530 Q96J02 Q99436 Q99460 Q99835 Q9HAU4 Q9HCE7 Q9UL46 Q9UMX1 Q9UNM6	C14orf41 C1orf28 C7orf76 CDC73 CUL3 DHH DSS1 DZIP DZIP1 DZIP2 EVC EVC2 GLI GLI1 GLI2 GLI3 GPR161 HC2 HC3 HC8 HC9 HRPT2 HSPC IFI5111 IHH ITCH KIAA0072 KIAA0077 KIAA0107 KIAA0617 KIAA0996 KIAA1625 KIF7 LBN LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NU NUMB PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 PTCH PTCH1 RBX1 RING10 RING12 RNF75 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SHH SMO SMOH SMURF1 SMURF2 SPOP SPOPL SUFU SUG1 SUG2 TBP1 TBP7 THP TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 ULK3 X Y Y2 Z
ABC-family proteins mediated transport	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 ABC-type oligopeptide transporter ABCB9 ABC-type organic anion transporter ABCA8 ATP-binding cassette sub-family B member 5 ATP-binding cassette sub-family C member 10 ATP-binding cassette sub-family C member 11 ATP-binding cassette sub-family C member 2 ATP-binding cassette sub-family C member 3 ATP-binding cassette sub-family C member 4 ATP-binding cassette sub-family C member 5 ATP-binding cassette sub-family C member 6 ATP-binding cassette sub-family C member 9 ATP-binding cassette sub-family F member 1 ATP-dependent translocase ABCB1 ATP-sensitive inward rectifier potassium channel 11 Cystic fibrosis transmembrane conductance regulator Derlin-1 Derlin-2 Derlin-3 E3 ubiquitin-protein ligase RNF185 E3 ubiquitin-protein ligase RNF5 Endoplasmic reticulum lectin 1 Erlin-1 Erlin-2 Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Multidrug resistance-associated protein 1 Phosphatidylcholine translocator ABCB4 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein OS-9 Protein sel-1 homolog 1 Retinal-specific phospholipid-transporting ATPase ABCA4 Transitional endoplasmic reticulum ATPase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O15438 O15439 O15440 O43242 O60706 O75477 O75832 O94905 O94911 O95255 P05198 P08183 P0CG47 P0CG48 P13569 P17980 P20042 P20618 P21439 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P33527 P35998 P40306 P41091 P43686 P48556 P49720 P49721 P51665 P55036 P55072 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 P78363 Q06323 Q13200 Q13438 Q14654 Q14997 Q15008 Q16401 Q2M3G0 Q5T3U5 Q8NE71 Q8TAA3 Q92530 Q92887 Q96DZ1 Q96GF1 Q96J66 Q96Q80 Q99436 Q99460 Q99942 Q9BUN8 Q9GZP9 Q9NP78 Q9UBV2 Q9UL46 Q9UNM6	ABC50 ABCA4 ABCA8 ABCB1 ABCB4 ABCB5 ABCB9 ABCC1 ABCC10 ABCC11 ABCC2 ABCC3 ABCC4 ABCC5 ABCC6 ABCC7 ABCC9 ABCF1 ABCR ARA C10orf69 C22orf14 C2orf30 C7orf76 C8orf2 CFTR CMOAT CMOAT1 CMOAT2 CMRP DER1 DER2 DER3 DERL1 DERL2 DERL3 DSS1 EIF2A EIF2B EIF2G EIF2S1 EIF2S2 EIF2S3 ERLEC1 ERLIN1 ERLIN2 FLANA G16 HC2 HC3 HC8 HC9 HEL-220 HEL-S-70 HSPC IFI5111 KCNJ11 KE04 KEO4 KIAA0072 KIAA0077 KIAA0107 KIAA0822 KIAA1520 LLN2 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MDR1 MDR3 MECL1 MIP224 MLP2 MOATB MOV34L MRP MRP1 MRP2 MRP3 MRP4 MRP5 MRP6 MRP7 MRP8 MSS1 NG2 NU OS9 PFAAP4 PGY1 PGY3 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RING10 RING12 RMA1 RNF185 RNF5 RPS27A SEL1L SEM1 SHFDG1 SHFM1 SIMRP7 SPFH1 SPFH2 SUG1 SUG2 SUR2 TBP1 TBP7 TRAP2 TSA305 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VCP X XTP3TPB Y Y2 Z
RUNX1 regulates transcription of genes involved in differentiation of HSCs	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 CDK-activating kinase assembly factor MAT1 Core-binding factor subunit beta Cyclin-H Cyclin-dependent kinase 7 E3 ubiquitin-protein ligase Itchy homolog Endothelial transcription factor GATA-2 Erythroid transcription factor Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Histone-lysine N-methyltransferase 2A LIM domain-binding protein 1 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Rhombotin-1 Rhombotin-2 Runt-related transcription factor 1 T-cell acute lymphocytic leukemia protein 1 Trans-acting T-cell-specific transcription factor GATA-3 Transcription factor 12 Transcription factor E2-alpha Transcription factor PU.1 Transcriptional activator Myb Transcriptional coactivator YAP1 Tumor protein p73 Tyrosine-protein kinase ABL1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O15350 O43242 O60814 O75832 P00519 P04908 P06899 P0C5Y9 P0CG47 P0CG48 P10242 P15923 P15976 P16104 P17542 P17947 P17980 P20618 P20671 P23527 P23769 P23771 P25786 P25787 P25788 P25789 P25791 P25800 P28062 P28065 P28066 P28070 P28072 P28074 P33778 P35998 P40306 P43686 P46937 P48556 P49720 P49721 P50613 P51665 P51946 P51948 P55036 P57053 P58876 P60896 P60900 P61289 P62191 P62195 P62333 P62805 P62807 P62979 P62987 P68431 P84243 Q01196 Q03164 Q06323 Q13200 Q13951 Q14997 Q15008 Q16401 Q16777 Q16778 Q6FI13 Q71DI3 Q71UI9 Q86U70 Q8N257 Q8TAA3 Q92530 Q93077 Q93079 Q96A08 Q96J02 Q99081 Q99436 Q99460 Q99877 Q99878 Q99879 Q99880 Q9BTM1 Q9UL46 Q9UNM6	ABL ABL1 ALL1 AML1 BHLHA17 BHLHB20 BHLHB21 C7orf76 CAK CAK1 CAP35 CBFA2 CBFB CCNH CDK7 CDKN7 CLIM2 CXXC7 DSS1 E2A ERYF1 GATA1 GATA2 GATA3 GF1 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HC2 HC3 HC8 HC9 HEB HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 HRX HSPC HTF4 HTRX IFI5111 ITCH ITF1 JTK7 KIAA0072 KIAA0077 KIAA0107 KMT2A LDB1 LMO1 LMO2 LMP10 LMP2 LMP7 LMPX LMPY MAT1 MB1 MCB1 MECL1 MIP224 MLL MLL1 MNAT1 MO15 MOV34L MSS1 MYB NU P73 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RBTN1 RBTN2 RBTNL1 RHOM1 RHOM2 RING10 RING12 RNF66 RPS27A RUNX1 SCL SEM1 SHFDG1 SHFM1 SPI1 STK1 SUG1 SUG2 TAL1 TBP1 TBP7 TCF12 TCF3 TCL5 TP73 TRAP2 TRX1 TSH2B TTG1 TTG2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 YAP1 YAP65 Z
Degradation of beta-catenin by the destruction complex	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 APC membrane recruitment protein 1 Adenomatous polyposis coli protein Axin-1 Casein kinase I isoform alpha Catenin beta-1 Cullin-1 E3 ubiquitin-protein ligase RBX1 F-box/WD repeat-containing protein 1A Glycogen synthase kinase-3 beta Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 S-phase kinase-associated protein 1 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Ubiquitin thioesterase ZRANB1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O15169 O43242 O75832 P0CG47 P0CG48 P17980 P20618 P25054 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P30153 P30154 P35222 P35998 P40306 P43686 P48556 P48729 P49720 P49721 P49841 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62714 P62877 P62979 P62987 P63208 P67775 Q06323 Q13200 Q13362 Q13616 Q14738 Q14997 Q15008 Q15172 Q15173 Q16401 Q16537 Q5JTC6 Q8TAA3 Q92530 Q99436 Q99460 Q9UGI0 Q9UL46 Q9UNM6 Q9Y297	AMER1 APC AXIN AXIN1 BTRC BTRCP C7orf76 CSNK1A1 CTNNB CTNNB1 CUL1 DP2.5 DSS1 EMC19 FAM123B FBW1A FBXW1A GSK3B HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0044 KIAA0072 KIAA0077 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NU OCP2 PFAAP4 POH1 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RBX1 RING10 RING12 RNF75 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SUG1 SUG2 TBP1 TBP7 TCEB1L TRABID TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WTX X Y Y2 Z ZRANB1
Degradation of AXIN	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Axin-1 Axin-2 E3 ubiquitin-protein ligase RNF146 E3 ubiquitin-protein ligase SMURF2 Poly [ADP-ribose] polymerase tankyrase-1 Poly [ADP-ribose] polymerase tankyrase-2 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O15169 O43242 O75832 O95271 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q06323 Q13200 Q14997 Q15008 Q16401 Q8TAA3 Q92530 Q99436 Q99460 Q9H2K2 Q9HAU4 Q9NTX7 Q9UL46 Q9UNM6 Q9Y2T1	AXIN AXIN1 AXIN2 C7orf76 DSS1 HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0077 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NU PARP5A PARP5B PARPL PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RING10 RING12 RNF146 RPS27A SEM1 SHFDG1 SHFM1 SMURF2 SUG1 SUG2 TANK2 TBP1 TBP7 TIN1 TINF1 TNKL TNKS TNKS1 TNKS2 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 Z
NIK-->noncanonical NF-kB signaling	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-1 F-box/WD repeat-containing protein 11 F-box/WD repeat-containing protein 1A Inhibitor of nuclear factor kappa-B kinase subunit alpha Mitogen-activated protein kinase kinase kinase 14 NEDD8-activating enzyme E1 catalytic subunit NEDD8-conjugating enzyme Ubc12 Nuclear factor NF-kappa-B p100 subunit Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 S-phase kinase-associated protein 1 Transcription factor RelB Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O15111 O43242 O75832 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61081 P61289 P62191 P62195 P62333 P62979 P62987 P63208 Q00653 Q01201 Q06323 Q13200 Q13616 Q14997 Q15008 Q16401 Q8TAA3 Q8TBC4 Q92530 Q99436 Q99460 Q99558 Q9UKB1 Q9UL46 Q9UNM6 Q9Y297	BTRC BTRCP BTRCP2 C7orf76 CHUK CUL1 DSS1 EMC19 FBW1A FBW1B FBXW11 FBXW1A FBXW1B HC2 HC3 HC8 HC9 HSPC IFI5111 IKKA KIAA0072 KIAA0077 KIAA0107 KIAA0696 LMP10 LMP2 LMP7 LMPX LMPY LYT10 MAP3K14 MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NFKB2 NIK NU OCP2 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RELB RING10 RING12 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SUG1 SUG2 TBP1 TBP7 TCEB1L TCF16 TRAP2 UBA3 UBA52 UBA80 UBB UBC UBC12 UBCEP1 UBCEP2 UBE1C UBE2M X Y Y2 Z
Dectin-1 mediated noncanonical NF-kB signaling	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-1 F-box/WD repeat-containing protein 11 F-box/WD repeat-containing protein 1A Inhibitor of nuclear factor kappa-B kinase subunit alpha Mitogen-activated protein kinase kinase kinase 14 NEDD8-activating enzyme E1 catalytic subunit NEDD8-conjugating enzyme Ubc12 Nuclear factor NF-kappa-B p100 subunit Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 S-phase kinase-associated protein 1 Transcription factor RelB Transcription factor p65 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O15111 O43242 O75832 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61081 P61289 P62191 P62195 P62333 P62979 P62987 P63208 Q00653 Q01201 Q04206 Q06323 Q13200 Q13616 Q14997 Q15008 Q16401 Q8TAA3 Q8TBC4 Q92530 Q99436 Q99460 Q99558 Q9UKB1 Q9UL46 Q9UNM6 Q9Y297	BTRC BTRCP BTRCP2 C7orf76 CHUK CUL1 DSS1 EMC19 FBW1A FBW1B FBXW11 FBXW1A FBXW1B HC2 HC3 HC8 HC9 HSPC IFI5111 IKKA KIAA0072 KIAA0077 KIAA0107 KIAA0696 LMP10 LMP2 LMP7 LMPX LMPY LYT10 MAP3K14 MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NFKB2 NFKB3 NIK NU OCP2 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RELA RELB RING10 RING12 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SUG1 SUG2 TBP1 TBP7 TCEB1L TCF16 TRAP2 UBA3 UBA52 UBA80 UBB UBC UBC12 UBCEP1 UBCEP2 UBE1C UBE2M X Y Y2 Z
UCH proteinases	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Actin, cytoplasmic 1 Actin-like protein 6A Actin-related protein 5 Actin-related protein 8 BRCA1-associated RING domain protein 1 Chromatin-remodeling ATPase INO80 Forkhead box protein K1 Forkhead box protein K2 Histone H2A type 1-A Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-H Histone H2A type 1-J Histone H2A type 1 Histone H2A type 2-A Histone H2A type 2-B Histone H2A type 2-C Histone H2A type 3 Host cell factor 1 INO80 complex subunit B INO80 complex subunit C INO80 complex subunit D INO80 complex subunit E Lysine-specific histone demethylase 2 Methyl-CpG-binding domain protein 5 Methyl-CpG-binding domain protein 6 Microspherule protein 1 Mothers against decapentaplegic homolog 7 NEDD8 Nuclear factor related to kappa-B-binding protein Polycomb group protein ASXL1 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Putative Polycomb group protein ASXL2 RuvB-like 1 Sentrin-specific protease 8 TCF3 fusion partner TGF-beta receptor type-1 TGF-beta receptor type-2 Transcriptional repressor protein YY1 Transforming growth factor beta-1 proprotein UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit Ubiquitin carboxyl-terminal hydrolase 15 Ubiquitin carboxyl-terminal hydrolase BAP1 Ubiquitin carboxyl-terminal hydrolase isozyme L1 Ubiquitin carboxyl-terminal hydrolase isozyme L3 Ubiquitin carboxyl-terminal hydrolase isozyme L5 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O15105 O15294 O43242 O75832 O96019 P01137 P04908 P09936 P0C0S8 P0C1Z6 P0CG47 P0CG48 P15374 P17980 P20618 P20671 P25490 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P36897 P37173 P40306 P43686 P48556 P49720 P49721 P51610 P51665 P55036 P60709 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 P85037 Q01167 Q06323 Q13200 Q14997 Q15008 Q15843 Q16186 Q16401 Q16777 Q53TQ3 Q6FI13 Q6P4R8 Q6PI98 Q76L83 Q7L7L0 Q8IUE6 Q8IXJ9 Q8NB78 Q8NBZ0 Q8TAA3 Q92530 Q92560 Q93077 Q96DN6 Q96EZ8 Q96KK5 Q96LD8 Q96QV6 Q99436 Q99460 Q99728 Q99878 Q9C086 Q9H981 Q9H9F9 Q9P267 Q9UL46 Q9ULG1 Q9UNM6 Q9Y265 Q9Y4E8 Q9Y5K5	ACTB ACTL6A ACTR5 ACTR8 ADRM1 ALK5 AOF1 ARP5 ARP8 ASXH2 ASXL1 ASXL2 BAF53 BAF53A BAP1 BARD1 C18orf37 C6orf193 C7orf76 CCDC95 DEN1 DSS1 FOXK1 FOXK2 GP110 H2AC1 H2AC11 H2AC12 H2AC13 H2AC14 H2AC15 H2AC16 H2AC17 H2AC18 H2AC19 H2AC20 H2AC21 H2AC25 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFC H2AFD H2AFE H2AFG H2AFI H2AFL H2AFM H2AFN H2AFO H2AFP H2AFQ H2AFR H2AW HC2 HC3 HC8 HC9 HCF1 HCFC1 HFC1 HIST1H2AA HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AG HIST1H2AH HIST1H2AI HIST1H2AJ HIST1H2AK HIST1H2AL HIST1H2AM HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AB HIST2H2AC HIST3H2A HMGA1L4 HSPC IFI5111 ILF ILF1 INO80 INO80A INO80B INO80C INO80D INO80E INO80F INO80G INO80H INO80K INO80N INO80Q INO80S INOC1 KDM1B KIAA0072 KIAA0077 KIAA0107 KIAA0272 KIAA0529 KIAA0978 KIAA1259 KIAA1461 KIAA1685 KIAA1887 LMP10 LMP2 LMP7 LMPX LMPY LSD2 MADH7 MADH8 MB1 MBD5 MBD6 MCB1 MCRS1 MECL1 MIP224 MNF MOV34L MSP58 MSS1 NEDD8 NEDP1 NFRKB NMP238 NU OGT PAPA1 PFAAP4 POH1 PROS26 PROS27 PROS30 PRSC2 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RING10 RING12 RPS27A RUVBL1 SEM1 SENP8 SHFDG1 SHFM1 SKR4 SMAD7 SUG1 SUG2 TBP1 TBP7 TFPT TGFB TGFB1 TGFBR1 TGFBR2 TIP49 TIP49A TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UCH37 UCHL1 UCHL3 UCHL5 USP15 X Y Y2 YY1 Z ZNHIT4
Regulation of ornithine decarboxylase (ODC)	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Antizyme inhibitor 1 NAD(P)H dehydrogenase [quinone] 1 Ornithine decarboxylase antizyme 1 Ornithine decarboxylase antizyme 2 Ornithine decarboxylase antizyme 3 Ornithine decarboxylase Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9	A5LHX3 O00231 O00232 O00233 O00487 O14818 O14977 O43242 O75832 O95190 P11926 P15559 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P54368 P55036 P60896 P60900 P61289 P62191 P62195 P62333 Q06323 Q13200 Q14997 Q15008 Q16401 Q8TAA3 Q92530 Q99436 Q99460 Q9UL46 Q9UMX2 Q9UNM6	AZIN1 C7orf76 DIA4 DSS1 HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0077 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NMOR1 NQO1 NU OAZ OAZ1 OAZ2 OAZ3 OAZI OAZIN ODC1 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RING10 RING12 SEM1 SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 X Y Y2 Z
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Aurora kinase A Cullin-1 E3 ubiquitin-protein ligase RBX1 F-box/LRR-repeat protein 18 F-box/LRR-repeat protein 7 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 S-phase kinase-associated protein 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O14965 O43242 O75832 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62877 P62979 P62987 P63208 Q06323 Q13200 Q13616 Q14997 Q15008 Q16401 Q8TAA3 Q92530 Q96ME1 Q99436 Q99460 Q9UJT9 Q9UL46 Q9UNM6	AIK AIRK1 ARK1 AURA AURKA AYK1 BTAK C7orf76 CUL1 DSS1 EMC19 FBL18 FBL6 FBL7 FBXL18 FBXL7 HC2 HC3 HC8 HC9 HSPC IAK1 IFI5111 KIAA0072 KIAA0077 KIAA0107 KIAA0840 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NU OCP2 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RBX1 RING10 RING12 RNF75 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A STK15 STK6 SUG1 SUG2 TBP1 TBP7 TCEB1L TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 Z
Interleukin-1 signaling	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-1 Dual specificity mitogen-activated protein kinase kinase 6 E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase pellino homolog 1 E3 ubiquitin-protein ligase pellino homolog 2 E3 ubiquitin-protein ligase pellino homolog 3 F-box/WD repeat-containing protein 1A Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 alpha Interleukin-1 beta Interleukin-1 receptor antagonist protein Interleukin-1 receptor type 1 Interleukin-1 receptor type 2 Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase 3 Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-associated kinase-like 2 Mitogen-activated protein kinase kinase kinase 3 Mitogen-activated protein kinase kinase kinase 7 Myeloid differentiation primary response protein MyD88 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Nucleoprotein Nucleotide-binding oligomerization domain-containing protein 1 Nucleotide-binding oligomerization domain-containing protein 2 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Receptor-interacting serine/threonine-protein kinase 2 S-phase kinase-associated protein 1 Sequestosome-1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 6 Toll-interacting protein Transcription factor p65 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O14920 O15111 O43187 O43242 O43318 O43353 O75832 P01583 P01584 P0CG47 P0CG48 P0DTC9 P14778 P17980 P18510 P19838 P20618 P25786 P25787 P25788 P25789 P25963 P27930 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51617 P51665 P52564 P55036 P60896 P60900 P61088 P61289 P62191 P62195 P62333 P62877 P62979 P62987 P63208 Q04206 Q06323 Q13200 Q13404 Q13501 Q13616 Q14997 Q15008 Q15750 Q16401 Q8N2H9 Q8N5C8 Q8TAA3 Q92530 Q96FA3 Q99436 Q99460 Q99759 Q99836 Q9H0E2 Q9HAT8 Q9HC29 Q9NWZ3 Q9NYJ8 Q9UL46 Q9UNM6 Q9Y239 Q9Y297 Q9Y4K3 Q9Y616 Q9Y6K9	BLU BTRC BTRCP C7orf76 CARD15 CARD4 CARDIAK CHUK CROC1 CUL1 DSS1 EMC19 FBW1A FBXW1A FIP3 HC2 HC3 HC8 HC9 HSPC IFI5111 IKBA IKBKB IKBKG IKKA IKKB IL1A IL1B IL1F1 IL1F2 IL1F3 IL1R IL1R1 IL1R2 IL1RA IL1RB IL1RN IL1RT1 IRAK IRAK1 IRAK2 IRAK3 IRAK4 KIAA0072 KIAA0077 KIAA0107 KIAA0733 LMP10 LMP2 LMP7 LMPX LMPY MAD3 MAP2K6 MAP3K3 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MAPKKK3 MB1 MCB1 MECL1 MEK6 MEKK3 MIP224 MKK6 MOV34L MSS1 MYD88 N NEMO NFKB1 NFKB3 NFKBI NFKBIA NOD1 NOD2 NU OCP2 ORCA OSIL PELI1 PELI2 PELI3 PFAAP4 POH1 PRISM PRKMK6 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RBX1 RELA RICK RING10 RING12 RIP2 RIPK2 RNF75 RNF85 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SKK3 SKP1 SKP1A SQSTM1 SUG1 SUG2 TAB1 TAB2 TAB3 TAK1 TBP1 TBP7 TCEB1L TCF16 TOLLIP TRAF6 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBE2N UBE2V UBE2V1 UEV1 X Y Y2 Z
CLEC7A (Dectin-1) signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 3-phosphoinositide-dependent protein kinase 1 B-cell lymphoma/leukemia 10 C-type lectin domain family 7 member A Caspase recruitment domain-containing protein 11 Caspase recruitment domain-containing protein 9 Cullin-1 F-box/WD repeat-containing protein 11 F-box/WD repeat-containing protein 1A Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Mitogen-activated protein kinase kinase kinase 7 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein kinase C delta type S-phase kinase-associated protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 6 Transcription factor p65 Tyrosine-protein kinase SYK Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 R1 Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O14920 O15111 O15530 O43242 O43318 O75832 O95999 P0CG47 P0CG48 P16885 P17980 P19838 P20618 P25786 P25787 P25788 P25789 P25963 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43405 P43686 P48556 P49427 P49720 P49721 P51665 P51668 P55036 P60896 P60900 P61088 P61289 P62191 P62195 P62333 P62837 P62979 P62987 P63208 Q04206 Q05655 Q06323 Q13200 Q13404 Q13616 Q14997 Q15008 Q15750 Q16401 Q8N5C8 Q8TAA3 Q92530 Q99436 Q99460 Q9BXL7 Q9BXN2 Q9H257 Q9NYJ8 Q9UDY8 Q9UKB1 Q9UL46 Q9UNM6 Q9Y297 Q9Y4K3 Q9Y6K9	BCL10 BGR BLU BTRC BTRCP BTRCP2 C7orf76 CARD11 CARD9 CARMA1 CDC34 CHUK CIPER CLAP CLEC7A CLECSF12 CROC1 CUL1 DECTIN1 DSS1 EMC19 FBW1A FBW1B FBXW11 FBXW1A FBXW1B FIP3 HC2 HC3 HC8 HC9 HSPC IFI5111 IKBA IKBKB IKBKG IKKA IKKB KIAA0072 KIAA0077 KIAA0107 KIAA0696 KIAA0733 LMP10 LMP2 LMP7 LMPX LMPY MAD3 MALT1 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MB1 MCB1 MECL1 MIP224 MLT MOV34L MSS1 NEMO NFKB1 NFKB3 NFKBI NFKBIA NU OCP2 PDK1 PDPK1 PFAAP4 PKCD PLCG2 POH1 PRKCD PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 PUBC1 RELA RING10 RING12 RNF85 RPS27A SEM1 SFT SHFDG1 SHFM1 SKP1 SKP1A SUG1 SUG2 SYK TAB1 TAB2 TAB3 TAK1 TBP1 TBP7 TCEB1L TCF16 TRAF6 TRAP2 UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBCEP1 UBCEP2 UBCH3 UBCH4 UBCH5 UBCH5A UBCH5B UBE2D1 UBE2D2 UBE2N UBE2R1 UBE2V UBE2V1 UEV1 X Y Y2 Z
TNFR2 non-canonical NF-kB pathway	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 CD40 ligand Lymphotoxin-alpha Lymphotoxin-beta Mitogen-activated protein kinase kinase kinase 14 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 TNF receptor-associated factor 2 TNF receptor-associated factor 3 Tumor necrosis factor ligand superfamily member 11 Tumor necrosis factor ligand superfamily member 12 Tumor necrosis factor ligand superfamily member 13B Tumor necrosis factor ligand superfamily member 14 Tumor necrosis factor receptor superfamily member 11A Tumor necrosis factor receptor superfamily member 12A Tumor necrosis factor receptor superfamily member 13C Tumor necrosis factor receptor superfamily member 1B Tumor necrosis factor receptor superfamily member 3 Tumor necrosis factor	A5LHX3 O00231 O00232 O00233 O00487 O14788 O14818 O43242 O43508 O43557 O75832 P01374 P01375 P17980 P20333 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P29965 P35998 P36941 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 Q06323 Q06643 Q12933 Q13114 Q13200 Q13489 Q13490 Q14997 Q15008 Q16401 Q8TAA3 Q92530 Q96RJ3 Q99436 Q99460 Q99558 Q9NP84 Q9UL46 Q9UNM6 Q9Y275 Q9Y6Q6	API1 API2 APO3L BAFF BAFFR BIRC2 BIRC3 BLYS BR3 C7orf76 CAP-1 CD40L CD40LG CRAF1 D12S370 DR3LG DSS1 FN14 HC2 HC3 HC8 HC9 HSPC HVEML IFI5111 KIAA0072 KIAA0077 KIAA0107 LIGHT LMP10 LMP2 LMP7 LMPX LMPY LTA LTB LTBR MAP3K14 MB1 MCB1 MECL1 MIHB MIHC MIP224 MOV34L MSS1 NIK NU OPGL PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RANK RANKL RING10 RING12 RNF48 RNF49 SEM1 SHFDG1 SHFM1 SUG1 SUG2 TALL1 TBP1 TBP7 TNF TNFA TNFB TNFBR TNFC TNFCR TNFR2 TNFR3 TNFRSF11A TNFRSF12A TNFRSF13C TNFRSF1B TNFRSF3 TNFSF1 TNFSF11 TNFSF12 TNFSF13B TNFSF14 TNFSF2 TNFSF20 TNFSF3 TNFSF5 TRAF2 TRAF3 TRAFAMN TRANCE TRAP TRAP2 TRAP3 X Y Y2 Z ZTNF4
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 M-phase inducer phosphatase 1 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Serine/threonine-protein kinase Chk1 Serine/threonine-protein kinase Chk2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14757 O14818 O43242 O75832 O96017 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P30304 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q06323 Q13200 Q14997 Q15008 Q16401 Q8TAA3 Q92530 Q99436 Q99460 Q9UL46 Q9UNM6	C7orf76 CDC25A CDS1 CHEK1 CHEK2 CHK1 CHK2 DSS1 HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0077 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NU PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RAD53 RING10 RING12 RPS27A SEM1 SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 Z
Asymmetric localization of PCP proteins	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 E3 ubiquitin-protein ligase SMURF1 E3 ubiquitin-protein ligase SMURF2 Frizzled-1 Frizzled-2 Frizzled-3 Frizzled-4 Frizzled-5 Frizzled-7 Frizzled-8 Partitioning defective 6 homolog alpha Polyubiquitin-B Polyubiquitin-C Prickle-like protein 1 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein Wnt-5a Protein scribble homolog Segment polarity protein dishevelled homolog DVL-2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Vang-like protein 2	A5LHX3 O00231 O00232 O00233 O00487 O14641 O14818 O43242 O75084 O75832 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P41221 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q06323 Q13200 Q13467 Q14160 Q14332 Q14997 Q15008 Q16401 Q8TAA3 Q92530 Q96MT3 Q99436 Q99460 Q9H461 Q9HAU4 Q9HCE7 Q9NPB6 Q9NPG1 Q9UL46 Q9ULK5 Q9ULV1 Q9UNM6 Q9UP38	C2orf31 C7orf76 CRIB1 DSS1 DVL2 FZD1 FZD2 FZD3 FZD4 FZD5 FZD7 FZD8 HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0077 KIAA0107 KIAA0147 KIAA1215 KIAA1625 LAP4 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NU PAR6A PARD6A PFAAP4 POH1 PRICKLE1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RILP RING10 RING12 RPS27A SCRB1 SCRIB SEM1 SHFDG1 SHFM1 SMURF1 SMURF2 STB1 SUG1 SUG2 TBP1 TBP7 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VANGL2 VARTUL WNT5A X Y Y2 Z
Degradation of DVL	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-3 Dapper homolog 1 E3 ubiquitin-protein ligase HECW1 E3 ubiquitin-protein ligase RBX1 Kelch-like protein 12 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Segment polarity protein dishevelled homolog DVL-1 Segment polarity protein dishevelled homolog DVL-2 Segment polarity protein dishevelled homolog DVL-3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14640 O14641 O14818 O43242 O75832 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62877 P62979 P62987 Q06323 Q13200 Q13618 Q14997 Q15008 Q16401 Q53G59 Q76N89 Q8TAA3 Q92530 Q92997 Q99436 Q99460 Q9NYF0 Q9UL46 Q9UNM6	C3IP1 C7orf76 CUL3 DACT1 DPR1 DSS1 DVL1 DVL2 DVL3 HC2 HC3 HC8 HC9 HECW1 HNG3 HSPC IFI5111 KIAA0072 KIAA0077 KIAA0107 KIAA0208 KIAA0322 KIAA0617 KLHL12 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NEDL1 NU PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RBX1 RING10 RING12 RNF75 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 Z
MAPK6/MAPK4 signaling	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cdc42 effector protein 2 Cdc42 effector protein 3 Cdc42 effector protein 5 Cell division control protein 42 homolog Cyclin-dependent kinase 1 DnaJ homolog subfamily B member 1 Dual specificity protein phosphatase CDC14A Dual specificity protein phosphatase CDC14B ETS translocation variant 4 Exportin-1 Forkhead box protein O1 Forkhead box protein O3 G1/S-specific cyclin-D3 Heat shock protein beta-1 Helicase MOV-10 Insulin-like growth factor 2 mRNA-binding protein 1 Kalirin MAP kinase-activated protein kinase 5 Mitogen-activated protein kinase 4 Mitogen-activated protein kinase 6 Myc proto-oncogene protein Nuclear receptor coactivator 3 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Ras-related C3 botulinum toxin substrate 1 Septin-7 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Transcription factor Jun Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein V(D)J recombination-activating protein 1 V(D)J recombination-activating protein 2 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	A5LHX3 O00231 O00232 O00233 O00487 O14613 O14818 O14980 O43242 O43524 O60229 O60729 O75832 O75914 P01106 P04792 P05412 P06493 P0CG47 P0CG48 P15918 P17612 P17980 P20618 P22612 P22694 P25685 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P30281 P31152 P35998 P40306 P43268 P43686 P48556 P49720 P49721 P51665 P55036 P55895 P60896 P60900 P60953 P61289 P62191 P62195 P62333 P62979 P62987 P63000 Q06323 Q12778 Q13153 Q13177 Q13200 Q14997 Q15008 Q16181 Q16401 Q16659 Q6NZY7 Q8IW41 Q8NDV7 Q8TAA3 Q92530 Q99436 Q99460 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9NZI8 Q9UKI2 Q9UKV8 Q9UL18 Q9UL46 Q9UNH5 Q9UNM6 Q9UPQ9 Q9Y6Q9	AGO1 AGO2 AGO3 AGO4 AIB1 BHLHE39 BHLHE42 BORG1 BORG2 BORG3 C7orf76 CAGH26 CCND3 CDC10 CDC14A CDC14B CDC2 CDC28A CDC42 CDC42EP2 CDC42EP3 CDC42EP5 CDK1 CDKN1 CEP2 CEP3 CEP5 CRDBP CRM1 DNAJ1 DNAJB1 DSS1 DUET DUO E1AF EIF2C1 EIF2C2 EIF2C3 EIF2C4 ERK3 ERK4 ETV4 FKHR FKHRL1 FOXO1 FOXO1A FOXO3 FOXO3A HAPIP HC2 HC3 HC8 HC9 HDJ1 HSP27 HSP28 HSPB1 HSPC HSPF1 IFI5111 IGF2BP1 JUN KALRN KIAA0072 KIAA0077 KIAA0107 KIAA1093 KIAA1460 KIAA1567 KIAA1582 KIAA1631 LMP10 LMP2 LMP7 LMPX LMPY MAPK4 MAPK6 MAPKAPK5 MB1 MCB1 MECL1 MIP224 MOV10 MOV34L MSS1 MYC NCOA3 NU OPHN3 P34CDC2 PAK1 PAK2 PAK3 PEA3 PFAAP4 PKACA POH1 PRAK PRKACA PRKACB PRKACG PRKM4 PRKM6 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RAC1 RAC3 RAG1 RAG2 RING10 RING12 RNF74 RPS27A SEM1 SEPT7 SEPTIN7 SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TC25 TNRC6 TNRC6A TNRC6B TNRC6C TRAD TRAM1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VICKZ1 X XPO1 Y Y2 Z ZBP1

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