Drug-mediated inhibition of CDK4/CDK6 activity
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- BCL1
- CCND1
- CCND2
- CCND3
- CDK4
- CDK6
- CDKN6
- PRAD1
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NVP-TAE684-resistant ALK mutants
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NFG and proNGF binds to p75NTR
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- NGF
- NGFB
- NGFR
- SORCS3
- TNFRSF16
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Phase 2 - plateau phase
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- AKAP350
- AKAP450
- AKAP9
- AMMECR2
- CACH2
- CACN2
- CACNA1C
- CACNA2D2
- CACNB1
- CACNB2
- CACNG4
- CACNG6
- CACNG7
- CACNG8
- CACNL1A1
- CACNLB1
- CACNLB2
- CCHL1A1
- KCNA8
- KCNA9
- KCNE1
- KCNE1L
- KCNE2
- KCNE3
- KCNE4
- KCNE5
- KCNQ1
- KIAA0558
- KIAA0803
- KVLQT1
- MYSB
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Interleukin receptor SHC signaling
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- CSF2
- CSF2R
- CSF2RA
- CSF2RB
- CSF2RY
- GAB2
- GMCSF
- GRB1
- HCP
- IL15RB
- IL2
- IL2RA
- IL2RB
- IL2RG
- IL3
- IL3R
- IL3RA
- IL3RB
- IL5
- IL5R
- IL5RA
- IL5RB
- INPP5D
- INPPL1
- JAK1
- JAK1A
- JAK1B
- JAK2
- JAK3
- KIAA0571
- PIK3C1
- PIK3CA
- PIK3CB
- PIK3CD
- PIK3R1
- PIK3R2
- PIK3R3
- PTP1C
- PTPN6
- SHC
- SHC1
- SHCA
- SHIP
- SHIP1
- SHIP2
- SOS1
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Formation of the Editosome
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- A1CF
- ACF
- APOBEC1
- APOBEC1L
- APOBEC2
- APOBEC3A
- APOBEC3B
- APOBEC3C
- APOBEC3H
- APOBEC4
- ASP
- C1orf169
- PBI
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Uncoating of the HIV Virion
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- CYPA
- PPIA
- gag
- gag-pol
- nef
- rev
- vif
- vpr
- vpu
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TNFR1-mediated ceramide production
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- FAN
- GNB2L1
- NSMAF
- RACK1
- SMPD2
- SMPD3
- TNF
- TNFA
- TNFAR
- TNFR1
- TNFRSF1A
- TNFSF2
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Interleukin-35 Signalling
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- APRF
- CANX
- CRL1
- EBI3
- IL12A
- IL12RB2
- IL27B
- IL27RA
- IL6ST
- JAK1
- JAK1A
- JAK1B
- JAK2
- NKSF1
- STAT1
- STAT3
- STAT4
- TCCR
- TYK2
- WSX1
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The retinoid cycle in cones (daylight vision)
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- AWAT2
- BCP
- CRALBP
- DC4
- DGAT2L4
- DHRS3
- GCP
- MFAT
- OPN1LW
- OPN1MW
- OPN1SW
- RBP3
- RCP
- RDH17
- RLBP1
- SDR16C1
- WS
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Synthesis of GDP-mannose
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- GMPPA
- GMPPB
- MPI
- PMI1
- PMM1
- PMM2
- PMMH22
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Constitutive Signaling by NOTCH1 PEST Domain Mutants
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- AD3
- AD4
- ADAM10
- ADAM17
- APH1A
- APH1B
- BHLHB31
- BHLHB32
- BHLHB33
- BHLHB38
- BHLHB39
- BHLHE39
- CBP
- CCNC
- CDK8
- CG1
- CHF1
- CHF2
- CREBBP
- CSVP
- CTG26
- CUL1
- CXorf6
- DIP1
- DLL1
- DLL4
- EMC19
- EP300
- GCN5
- GCN5L2
- GRL
- HDAC1
- HDAC10
- HDAC11
- HDAC2
- HDAC3
- HDAC4
- HDAC5
- HDAC6
- HDAC7
- HDAC7A
- HDAC7B
- HDAC8
- HDAC9
- HDACL1
- HDRP
- HERP
- HERP1
- HERP2
- HES1
- HES5
- HESR1
- HEY1
- HEY2
- HEYL
- HL
- HRT1
- HRT2
- HRT3
- HRY
- IGKJRB
- IGKJRB1
- IRA1
- JAG1
- JAG2
- JAGL1
- KAT2A
- KAT2B
- KIAA0200
- KIAA0253
- KIAA0288
- KIAA0600
- KIAA0744
- KIAA0901
- KIAA1047
- KIAA1323
- KIAA1816
- KIAA1819
- KUZ
- MADM
- MAML1
- MAML2
- MAML3
- MAMLD1
- MIB1
- MIB2
- MITR
- MYC
- NCOR1
- NCOR2
- NCSTN
- NEURL
- NEURL1
- NEURL1A
- NEURL1B
- NEURL3
- NOTCH1
- OCP2
- P300
- PCAF
- PEN2
- PS1
- PS2
- PSEN1
- PSEN2
- PSENEN
- PSF
- PSFL
- PSNL1
- PSNL2
- RBPJ
- RBPJK
- RBPSUH
- RBX1
- RNF67
- RNF75
- ROC1
- RPD3L1
- RPS27A
- SKD
- SKIIP
- SKIP
- SKP1
- SKP1A
- SNW1
- STM2
- TACE
- TAN1
- TBL1
- TBL1X
- TBL1XR1
- TBLR1
- TCEB1L
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- ZZANK1
- ZZANK2
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ATF4 activates genes in response to endoplasmic reticulum stress
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- ASNS
- ATF3
- ATF4
- ATF6
- CCL2
- CEBPB
- CEBPG
- CHOP
- CHOP10
- CML28
- CREB2
- CSL4
- CXCL8
- DAN
- DCP2
- DDIT3
- DIS3
- EXOSC1
- EXOSC2
- EXOSC3
- EXOSC4
- EXOSC5
- EXOSC6
- EXOSC7
- EXOSC8
- EXOSC9
- FUBP2
- GADD153
- HAP3
- HERP
- HERPUD1
- IBP1
- IGFBP1
- IL8
- KHSRP
- KIAA0025
- KIAA0116
- KIAA1008
- MCP1
- MIF1
- MTR3
- NFYA
- NFYB
- NFYC
- NUDT20
- OIP2
- PARN
- PMSCL1
- RRP4
- RRP40
- RRP41
- RRP42
- RRP43
- RRP44
- RRP46
- SCYA2
- SKI6
- TCF5
- TS11
- TXREB
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SHC-mediated cascade:FGFR2
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- FGF1
- FGF10
- FGF16
- FGF18
- FGF2
- FGF20
- FGF22
- FGF23
- FGF3
- FGF4
- FGF6
- FGF7
- FGF9
- FGFA
- FGFB
- HRAS
- HRAS1
- HST
- HST2
- HSTF1
- HSTF2
- HYPF
- INT2
- KGF
- KS3
- NRAS
- SOS1
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Phospholipase C-mediated cascade; FGFR4
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- FGF1
- FGF16
- FGF18
- FGF19
- FGF2
- FGF20
- FGF23
- FGF4
- FGF6
- FGF9
- FGFA
- FGFB
- FGFR4
- HST
- HST2
- HSTF1
- HSTF2
- HYPF
- JTK2
- KLB
- KS3
- PLC1
- PLCG1
- TKF
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Interleukin-23 signaling
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- APRF
- ERBA2L
- IL12B
- IL12R
- IL12RB
- IL12RB1
- IL23A
- IL23R
- JAK2
- NKSF2
- P4HB
- PDI
- PDIA1
- PO4DB
- SGRF
- STAT3
- STAT4
- TYK2
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Signaling by PDGFRA extracellular domain mutants
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- APRF
- GRB1
- HRAS
- HRAS1
- NRAS
- PDGFR2
- PDGFRA
- PIK3C1
- PIK3CA
- PIK3CB
- PIK3R1
- PIK3R2
- RHEPDGFRA
- SOS1
- STAT1
- STAT3
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Signalling to RAS
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- HRAS
- HRAS1
- MTC
- NGF
- NGFB
- NRAS
- NSHC
- NTRK1
- SCK
- SHC
- SHC1
- SHC2
- SHC3
- SHCA
- SHCB
- SHCC
- SOS1
- TRK
- TRKA
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Activation of BIM and translocation to mitochondria
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- BCL2L11
- BIM
- DLC1
- DNCL1
- DNCLC1
- DYNLL1
- HDLC1
- JNK1
- MAPK8
- PRKM8
- SAPK1
- SAPK1C
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Defective CHSY1 causes TPBS
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- BCAN
- BEHAB
- BGN
- CALEB
- CHSY
- CHSY1
- CSPG2
- CSPG3
- CSPG4
- CSPG5
- CSPG7
- CSS1
- DCN
- KIAA0990
- MCSP
- NCAN
- NEUR
- NGC
- SLRR1A
- SLRR1B
- VCAN
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Defective MTR causes HMAG
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Formation of editosomes by ADAR proteins
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- ADAR
- ADAR1
- ADAR2
- ADARB1
- DRADA2
- DSRAD
- G1P1
- IFI4
- RED1
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Mitochondrial tRNA aminoacylation
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- Alanine--tRNA ligase, mitochondrial
- Asparaginyl-tRNA synthetase
- Aspartate--tRNA ligase, mitochondrial
- Glutamine--tRNA ligase
- Glycine--tRNA ligase
- Histidine--tRNA ligase, mitochondrial
- Inorganic pyrophosphatase 2, mitochondrial
- Isoleucine--tRNA ligase, mitochondrial
- Leucine--tRNA ligase, mitochondrial
- Lysine--tRNA ligase
- Methionine--tRNA ligase, mitochondrial
- Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial
- Phenylalanine--tRNA ligase, mitochondrial
- Probable arginine--tRNA ligase, mitochondrial
- Probable cysteine--tRNA ligase, mitochondrial
- Probable proline--tRNA ligase, mitochondrial
- Serine--tRNA ligase, mitochondrial
- Threonine--tRNA ligase, mitochondrial
- Tryptophan--tRNA ligase, mitochondrial
- Tyrosine--tRNA ligase, mitochondrial
- Valine--tRNA ligase, mitochondrial
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- AARS2
- AARSL
- CARS2
- DARS2
- EARS2
- FARS1
- FARS2
- GARS
- GARS1
- HARS2
- HARSL
- HARSR
- HO3
- IARS2
- KARS
- KARS1
- KIAA0028
- KIAA0070
- KIAA1270
- KIAA1885
- KIAA1970
- LARS2
- MARS2
- NARS2
- PARS2
- PPA2
- QARS
- QARS1
- RARS2
- RARSL
- SARS2
- SARSM
- TARS2
- TARSL1
- VARS2
- VARS2L
- VARSL
- WARS2
- YARS2
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Constitutive Signaling by NOTCH1 HD Domain Mutants
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- ADAM10
- ADAM17
- CSVP
- DIP1
- DLL1
- DLL4
- JAG1
- JAG2
- JAGL1
- KIAA1323
- KUZ
- MADM
- MIB1
- MIB2
- NEURL
- NEURL1
- NEURL1A
- NEURL1B
- NEURL3
- NOTCH1
- RNF67
- RPS27A
- SKD
- TACE
- TAN1
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- ZZANK1
- ZZANK2
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Classical antibody-mediated complement activation
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- C1QA
- C1QB
- C1QC
- C1QG
- C1R
- C1S
- CRP
- IGHG1
- IGHG2
- IGHG3
- IGHG4
- IGHV
- IGHV1-2
- IGHV1-46
- IGHV1-69
- IGHV2-5
- IGHV2-70
- IGHV3-11
- IGHV3-13
- IGHV3-23
- IGHV3-30
- IGHV3-33
- IGHV3-48
- IGHV3-53
- IGHV3-7
- IGHV3-9
- IGHV4-34
- IGHV4-39
- IGHV4-59
- IGHV7-81
- IGKC
- IGKV1-12
- IGKV1-16
- IGKV1-17
- IGKV1-33
- IGKV1-39
- IGKV1-5
- IGKV1D-12
- IGKV1D-16
- IGKV1D-33
- IGKV1D-39
- IGKV2-28
- IGKV2-29
- IGKV2-30
- IGKV2D-28
- IGKV2D-30
- IGKV2D-40
- IGKV3-11
- IGKV3-15
- IGKV3-20
- IGKV3D-20
- IGKV4-1
- IGKV5-2
- IGLC1
- IGLC2
- IGLC3
- IGLC6
- IGLC7
- IGLV
- IGLV1-40
- IGLV1-44
- IGLV1-47
- IGLV1-51
- IGLV2-11
- IGLV2-14
- IGLV2-23
- IGLV2-8
- IGLV3-1
- IGLV3-19
- IGLV3-21
- IGLV3-25
- IGLV3-27
- IGLV6-57
- IGLV7-43
- PTX1
- V1-11
- V1-13
- V1-16
- V1-20
- V1-3
- V1-5
- V1-7
- V1-9
- V2-11
- V2-15
- V2-17
- V2-19
- V2-8
- V3-2
- V3-3
- V3-4
- V4-1
- V4-2
- V4-6
- V5-1
- V5-4
- V5-6
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