RND3 GTPase cycle
|
|
|
- ANKRD26
- APE
- ARHE
- ARHGAP10
- ARHGAP21
- ARHGAP35
- ARHGAP5
- BACURD1
- BACURD2
- BP230
- BP240
- BPAG1
- C6orf143
- CALM
- CAV
- CAV1
- CCDC88A
- CDHF4
- CG1
- CKAP4
- CKB
- CKBB
- CPD
- CRIB1
- DDX4
- DEPDC1B
- DLG5
- DMH
- DRCC1
- DSG1
- DSP
- DST
- DT
- ECK
- EDP1
- EPHA2
- ESA1
- FAM83B
- FLOT2
- GRB1
- GRDN
- GRF1
- GRLF1
- HNRPG
- IRAS
- KCTD13
- KIAA0004
- KIAA0147
- KIAA0583
- KIAA0720
- KIAA0728
- KIAA0975
- KIAA1074
- KIAA1212
- KIAA1215
- KIAA1424
- KIAA1722
- KTN1
- LAP4
- LEMD3
- M17S1
- MAN1
- MUC13
- NGAP
- NISCH
- P190A
- PDIP1
- PDLG
- PICALM
- PIK3R1
- PIK3R2
- PKP4
- PLEKHG5
- PNP1
- POLDIP1
- PTP1E
- PTPL1
- PTPN13
- RASAL2
- RBMX
- RBMXP1
- RECC
- RHO8
- RHOE
- RHOGAP5
- RND3
- ROCK1
- SCRB1
- SCRIB
- SEMA4F
- SEMAM
- SEMAW
- SOC
- STB1
- STB2
- TMOD3
- TNFAIP1
- TRP32
- TXL
- TXNL
- TXNL1
- UBXD5
- UBXN11
- VANGL1
- VANGL2
- VARTUL
- VASA
- WDR6
- XTP8
- p190ARHOGAP
|
Homo sapiens (human)
|
|
Downstream signal transduction
|
|
|
- APRF
- BCAR1
- CAS
- CASS1
- CRK
- CRKAS
- CRKL
- GAP
- GRB1
- GRB4
- GRB7
- GRF2
- HRAS
- HRAS1
- NCK
- NCK1
- NCK2
- NRAS
- PDGF2
- PDGFB
- PDGFR
- PDGFR1
- PDGFR2
- PDGFRA
- PDGFRB
- PIK3C1
- PIK3CA
- PIK3CB
- PIK3R1
- PIK3R2
- PLC1
- PLCG1
- PTP2C
- PTPN11
- RAPGEF1
- RASA
- RASA1
- RHEPDGFRA
- SHPTP2
- SIS
- SOS1
- SRC
- SRC1
- STAT1
- STAT3
- STAT5
- STAT5A
- STAT5B
- STAT6
|
Homo sapiens (human)
|
|
DAP12 signaling
|
|
|
- AGMX1
- ATK
- B2M
- BPK
- BTK
- CD94
- D12S2489E
- DAP12
- FYN
- GADS
- GRAP2
- GRB1
- GRB2L
- GRID
- HLA-6.2
- HLA-E
- HLAE
- HRAS
- HRAS1
- KARAP
- KLRC2
- KLRD1
- KLRK1
- LCK
- LCP2
- NKG2C
- NKG2D
- NRAS
- PIK3C1
- PIK3CA
- PIK3CB
- PIK3R1
- PIK3R2
- PLC1
- PLCG1
- PLCG2
- RAC1
- SOS1
- SYK
- TC25
- TREM2
- TYROBP
- VAV2
- VAV3
|
Homo sapiens (human)
|
|
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants
|
|
|
- APRF
- FYN
- GRB1
- HRAS
- HRAS1
- JAK2
- JTK8
- KIT
- LCK
- LYN
- NRAS
- PIK3CA
- PIK3R1
- PIK3R2
- PIK3R3
- SCFR
- SOS1
- STAT1
- STAT3
- STAT5
- STAT5A
- STAT5B
- YES
- YES1
|
Homo sapiens (human)
|
|
Costimulation by the CD28 family
|
|
|
- B7H2
- B7RP1
- BTLA
- GRB1
- HCP
- HVEA
- HVEM
- ICOSL
- ICOSLG
- KIAA0653
- PIK3CA
- PIK3R1
- PIK3R2
- PIK3R3
- PTP1C
- PTP2C
- PTPN11
- PTPN6
- SHPTP2
- TNFRSF14
|
Homo sapiens (human)
|
|
Signaling by ALK
|
|
|
- ALK
- ALKAL1
- ALKAL2
- APRF
- BHLHE37
- BHLHE39
- FAM150A
- FAM150B
- FRS2
- GRB1
- HBNF1
- HCP
- IRS1
- JAK3
- MDK
- MK1
- MYC
- MYCN
- NEGF1
- NEGF2
- NMYC
- PIK3C1
- PIK3CA
- PIK3CB
- PIK3R1
- PIK3R2
- PLC1
- PLCG1
- PTN
- PTP1C
- PTPN6
- STAT3
|
Homo sapiens (human)
|
|
Signaling by PDGFRA extracellular domain mutants
|
|
|
- APRF
- GRB1
- HRAS
- HRAS1
- NRAS
- PDGFR2
- PDGFRA
- PIK3C1
- PIK3CA
- PIK3CB
- PIK3R1
- PIK3R2
- RHEPDGFRA
- SOS1
- STAT1
- STAT3
|
Homo sapiens (human)
|
|
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants
|
|
|
- APRF
- GRB1
- HRAS
- HRAS1
- NRAS
- PDGFR2
- PDGFRA
- PIK3C1
- PIK3CA
- PIK3CB
- PIK3R1
- PIK3R2
- RHEPDGFRA
- SOS1
- STAT1
- STAT3
|
Homo sapiens (human)
|
|
PI3K/AKT activation
|
|
|
- ARH12
- ARHA
- GRB1
- IRS1
- IRS2
- MTC
- NGF
- NGFB
- NTRK1
- PIK3C1
- PIK3CA
- PIK3CB
- PIK3R1
- PIK3R2
- RHO12
- RHOA
- TRK
- TRKA
|
Homo sapiens (human)
|
|
Signaling by LTK in cancer
|
|
|
- CLIP1
- CYLN1
- ERK1
- ERK2
- GRB1
- MAPK1
- MAPK3
- PIK3C1
- PIK3CA
- PIK3CB
- PIK3R1
- PIK3R2
- PRKM1
- PRKM2
- PRKM3
- RSN
|
Homo sapiens (human)
|
|
Signaling by LTK
|
|
|
- ACK1
- ALKAL1
- ALKAL2
- ASH
- FAM150A
- FAM150B
- GRB1
- GRB2
- IRS1
- LTK
- PIK3C1
- PIK3CA
- PIK3CB
- PIK3R1
- PIK3R2
- SOS1
- TNK2
- TYK1
|
Homo sapiens (human)
|
|
IRS-mediated signalling
|
|
|
- GRB1
- IRS1
- IRS2
- PIK3C1
- PIK3CA
- PIK3CB
- PIK3R1
- PIK3R2
|
Homo sapiens (human)
|
|
Intra-Golgi traffic
|
|
|
- ALPP
- ARF1
- ARNO
- ARNO3
- BET1L
- CEV14
- CIP150
- COG1
- COG2
- COG3
- COG4
- COG5
- COG6
- COG7
- COG8
- CUTL1
- CUX1
- CYT4
- CYTH1
- CYTH2
- CYTH3
- CYTH4
- D17S811E
- GIMPC
- GOLGA5
- GOLIM4
- GOLPH4
- GOLTC1
- GOSR1
- GOSR2
- GPP130
- GRP1
- GS15
- GS27
- GS28
- GTC90
- KIAA0258
- KIAA1134
- KIAA1381
- KIAA1432
- LDLB
- LDLC
- MAN1A1
- MAN1A2
- MAN1A3
- MAN1B
- MAN1C
- MAN1C1
- MAN2A1
- MAN2A2
- MANA2
- MANA2X
- NAPA
- NAPB
- NAPG
- NSF
- PLAP
- PSCD1
- PSCD2
- PSCD2L
- PSCD3
- PSCD4
- RAB30
- RAB33B
- RAB36
- RAB39
- RAB39A
- RAB41
- RETII
- RFG5
- RGP1
- RIC1
- SEC34
- SNAP29
- SNAPA
- SNAPB
- SNAPG
- STX16
- STX5
- STX5A
- STX6
- TRIP11
- VPS45
- VPS45A
- VPS45B
- VTI1A
- YKT6
|
Homo sapiens (human)
|
|
Lysosomal oligosaccharide catabolism
|
|
|
- KIAA0935
- LAMAN
- MAN2B1
- MAN2B2
- MAN2C1
- MANA
- MANA1
- MANB
- MANB1
- MANBA
|
Homo sapiens (human)
|
|
ECM proteoglycans
|
|
|
- ACAN
- AGC1
- AGRIN
- AGRN
- ASPN
- BCAN
- BEHAB
- BGN
- BNSP
- CD11C
- CD49B
- CMP
- COL9A1
- COL9A2
- COL9A3
- COMP
- CRTL1
- CRTM
- CSPG1
- CSPG2
- CSPG3
- CSPG7
- DAG1
- DCN
- DMP1
- DSPP
- FM
- FMOD
- FNRB
- GP2B
- GP3A
- HAPLN1
- HSPG2
- HXB
- HXBL
- IBSP
- ITGA2
- ITGA2B
- ITGA7
- ITGA8
- ITGA9
- ITGAB
- ITGAV
- ITGAX
- ITGB1
- ITGB3
- ITGB5
- ITGB6
- KIAA0533
- KIAA0816
- KIAA1907
- LAMA
- LAMA1
- LAMA2
- LAMA3
- LAMA4
- LAMA5
- LAMB1
- LAMB2
- LAMC1
- LAMM
- LAMNA
- LAMS
- LDC
- LRP10
- LRP4
- LUM
- MATN1
- MATN3
- MATN4
- MDF2
- MEGF7
- MSK12
- MSK16
- MSK8
- MUSK
- NCAM
- NCAM1
- NCAN
- NEUR
- ON
- PAI1
- PLANH1
- PLAP1
- PTPRS
- SERPINE1
- SLRR1A
- SLRR1B
- SLRR1C
- SLRR2D
- SLRR2E
- SPARC
- TGFB
- TGFB1
- TGFB2
- TGFB3
- TNC
- TNN
- TNR
- TNW
- TNX
- TNXB
- TNXB1
- TNXB2
- VCAN
- VNRA
- VTN
- VTNR
- XB
|
Homo sapiens (human)
|
|
A tetrasaccharide linker sequence is required for GAG synthesis
|
|
|
- AGRIN
- AGRN
- B3GALT6
- B3GAT1
- B3GAT2
- B3GAT3
- B4GALT7
- BCAN
- BEHAB
- BGN
- CALEB
- CSPG2
- CSPG3
- CSPG4
- CSPG5
- CSPG7
- DCN
- GLCATP
- GLCATS
- GPC1
- GPC2
- GPC3
- GPC4
- GPC5
- GPC6
- HSPG1
- HSPG2
- KIAA0468
- KIAA1963
- MCSP
- NCAN
- NEUR
- NGC
- OCI5
- SDC
- SDC1
- SDC2
- SDC3
- SDC4
- SLRR1A
- SLRR1B
- VCAN
- XGALT1
- XT1
- XT2
- XYLT1
- XYLT2
|
Homo sapiens (human)
|
|
Defective B3GAT3 causes JDSSDHD
|
|
|
- AGRIN
- AGRN
- B3GAT3
- BCAN
- BEHAB
- BGN
- CALEB
- CSPG2
- CSPG3
- CSPG4
- CSPG5
- CSPG7
- DCN
- GPC1
- GPC2
- GPC3
- GPC4
- GPC5
- GPC6
- HSPG1
- HSPG2
- KIAA0468
- MCSP
- NCAN
- NEUR
- NGC
- OCI5
- SDC
- SDC1
- SDC2
- SDC3
- SDC4
- SLRR1A
- SLRR1B
- VCAN
|
Homo sapiens (human)
|
|
Defective B3GALT6 causes EDSP2 and SEMDJL1
|
|
|
- AGRIN
- AGRN
- B3GALT6
- BCAN
- BEHAB
- BGN
- CALEB
- CSPG2
- CSPG3
- CSPG4
- CSPG5
- CSPG7
- DCN
- GPC1
- GPC2
- GPC3
- GPC4
- GPC5
- GPC6
- HSPG1
- HSPG2
- KIAA0468
- MCSP
- NCAN
- NEUR
- NGC
- OCI5
- SDC
- SDC1
- SDC2
- SDC3
- SDC4
- SLRR1A
- SLRR1B
- VCAN
|
Homo sapiens (human)
|
|
Defective B4GALT7 causes EDS, progeroid type
|
|
|
- AGRIN
- AGRN
- B4GALT7
- BCAN
- BEHAB
- BGN
- CALEB
- CSPG2
- CSPG3
- CSPG4
- CSPG5
- CSPG7
- DCN
- GPC1
- GPC2
- GPC3
- GPC4
- GPC5
- GPC6
- HSPG1
- HSPG2
- KIAA0468
- MCSP
- NCAN
- NEUR
- NGC
- OCI5
- SDC
- SDC1
- SDC2
- SDC3
- SDC4
- SLRR1A
- SLRR1B
- VCAN
- XGALT1
|
Homo sapiens (human)
|
|
Attachment and Entry
|
|
|
- 3a
- 7a
- ACE2
- AGRIN
- AGRN
- CTSL
- CTSL1
- E
- FUR
- FURIN
- GPC1
- GPC2
- GPC3
- GPC4
- GPC5
- GPC6
- HAVCR1
- HEL-220
- HEL-S-70
- HSPG1
- HSPG2
- KIAA0468
- KIM1
- M
- N
- NRP
- NRP1
- OCI5
- PACE
- PCSK3
- PRSS10
- S
- SDC
- SDC1
- SDC2
- SDC3
- SDC4
- TIM1
- TIMD1
- TMPRSS2
- VCP
- VEGF165R
|
Homo sapiens (human)
|
|
HS-GAG biosynthesis
|
|
|
- 3OST
- 3OST1
- 3OST2
- 3OST3A1
- 3OST3B1
- 3OST4
- 3OST5
- AGRIN
- AGRN
- EXT1
- EXT2
- GLCE
- GPC1
- GPC2
- GPC3
- GPC4
- GPC5
- GPC6
- HFRC
- HS2ST
- HS2ST1
- HS3OST5
- HS3ST1
- HS3ST2
- HS3ST3A
- HS3ST3A1
- HS3ST3B
- HS3ST3B1
- HS3ST4
- HS3ST5
- HS3ST6
- HS6ST
- HS6ST1
- HS6ST2
- HS6ST3
- HSPG1
- HSPG2
- HSST
- HSST1
- HSST2
- HSST3
- HSST4
- KIAA0448
- KIAA0468
- KIAA0836
- NDST1
- NDST2
- NDST3
- NDST4
- OCI5
- SDC
- SDC1
- SDC2
- SDC3
- SDC4
- SLC35D2
- UGTREL8
|
Homo sapiens (human)
|
|
Non-integrin membrane-ECM interactions
|
|
|
- AGRIN
- AGRN
- CAK
- DAG1
- DDR1
- DDR2
- DMD
- EDDR1
- FGF2
- FGFB
- HSPG2
- KIAA0533
- KIAA0578
- KIAA1907
- LAMA
- LAMA1
- LAMA2
- LAMA3
- LAMA4
- LAMA5
- LAMB1
- LAMB2
- LAMB2T
- LAMB3
- LAMC1
- LAMC2
- LAMC3
- LAMM
- LAMNA
- LAMNB1
- LAMNB2
- LAMS
- NEP
- NRXN1
- NTN4
- NTRK4
- NTRKR3
- PALB
- PDGF1
- PDGF2
- PDGFA
- PDGFB
- PTK3A
- RTK6
- SIS
- TKT
- TRKE
- TTR
- TYRO10
|
Homo sapiens (human)
|
|
Retinoid metabolism and transport
|
|
|
- A2MR
- AGRIN
- AGRN
- AKR1B10
- AKR1B11
- AKR1C1
- AKR1C3
- AKR1C4
- APC2
- APOA1
- APOA2
- APOA4
- APOB
- APOC2
- APOC3
- APOE
- APOER2
- APOM
- APR
- ARSDR1
- BCDO
- BCDO1
- BCDO2
- BCMO1
- BCO1
- BCO2
- CHDR
- CLPS
- CRBP1
- CRBP2
- DDH
- DDH1
- G3A
- GPC1
- GPC2
- GPC3
- GPC4
- GPC5
- GPC6
- GPIHBP1
- HBP1
- HSD17B5
- HSPG1
- HSPG2
- KIAA0119
- KIAA0468
- LDLR
- LIPD
- LPL
- LRAT
- LRP1
- LRP10
- LRP12
- LRP2
- LRP8
- NG20
- OCI5
- PALB
- PGFS
- PLB
- PLB1
- PNLIP
- PPSIG
- PSDR1
- RBP1
- RBP2
- RBP4
- RDH11
- RETSAT
- SDC
- SDC1
- SDC2
- SDC3
- SDC4
- SDR7C1
- ST7
- TTR
|
Homo sapiens (human)
|
|
HS-GAG degradation
|
|
|
- AGRIN
- AGRN
- ELNR1
- GLB1
- GLB1L
- GLB1L2
- GLB1L3
- GPC1
- GPC2
- GPC3
- GPC4
- GPC5
- GPC6
- GUSB
- HEP
- HPA
- HPA1
- HPA2
- HPR1
- HPSE
- HPSE1
- HPSE2
- HSE1
- HSPG1
- HSPG2
- HSS
- IDS
- IDUA
- KIAA0468
- NAGLU
- OCI5
- SDC
- SDC1
- SDC2
- SDC3
- SDC4
- SGSH
- SIDS
- UFHSD1
|
Homo sapiens (human)
|
|
Defective EXT1 causes exostoses 1, TRPS2 and CHDS
|
|
|
- AGRIN
- AGRN
- EXT1
- EXT2
- GPC1
- GPC2
- GPC3
- GPC4
- GPC5
- GPC6
- HSPG1
- HSPG2
- KIAA0468
- OCI5
- SDC
- SDC1
- SDC2
- SDC3
- SDC4
|
Homo sapiens (human)
|
|