GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **176 - 200** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism	GlyTouCan ID
ER-Phagosome pathway	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Antigen peptide transporter 1 Antigen peptide transporter 2 Beta-2-microglobulin Calreticulin Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain HLA class I histocompatibility antigen, A alpha chain HLA class I histocompatibility antigen, B alpha chain HLA class I histocompatibility antigen, C alpha chain HLA class I histocompatibility antigen, alpha chain E HLA class I histocompatibility antigen, alpha chain F HLA class I histocompatibility antigen, alpha chain G High mobility group protein B1 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Lymphocyte antigen 96 Major outer membrane protein P.IB Monocyte differentiation antigen CD14 Myeloid differentiation primary response protein MyD88 NF-kappa-B essential modulator Peptidyl-prolyl cis-trans isomerase Mip Platelet glycoprotein 4 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein S100-A1 Protein S100-A8 Protein S100-A9 Protein disulfide-isomerase A3 Protein transport protein Sec61 subunit alpha isoform 1 Protein transport protein Sec61 subunit alpha isoform 2 Protein transport protein Sec61 subunit beta Protein transport protein Sec61 subunit gamma Putative HLA class I histocompatibility antigen, alpha chain H Synaptosomal-associated protein 23 Syntaxin-4 Tapasin Toll-like receptor 1 Toll-like receptor 2 Toll-like receptor 4 Toll-like receptor 6 Toll/interleukin-1 receptor domain-containing adapter protein Tyrosine-protein kinase BTK Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Vesicle-associated membrane protein 3 Vesicle-associated membrane protein 8 Vesicle-trafficking protein SEC22b	A5LHX3 O00161 O00206 O00231 O00232 O00233 O00487 O14818 O14920 O15111 O15533 O43242 O60603 O75396 O75832 P01889 P01893 P02671 P02675 P02679 P04439 P05109 P06702 P08571 P09429 P0CG47 P0CG48 P10321 P13747 P16671 P17693 P17980 P20618 P23297 P25786 P25787 P25788 P25789 P26623 P27797 P28062 P28065 P28066 P28070 P28072 P28074 P30101 P30511 P30690 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P58753 P60059 P60468 P60896 P60900 P61289 P61619 P61769 P62191 P62195 P62333 P62979 P62987 Q03518 Q03519 Q06187 Q06323 Q12846 Q13200 Q14997 Q15008 Q15399 Q15836 Q16401 Q8TAA3 Q92530 Q99436 Q99460 Q99836 Q9BV40 Q9H9S3 Q9UL46 Q9UNM6 Q9Y2C9 Q9Y6K9 Q9Y6Y9	ABCB2 ABCB3 AGMX1 ATK B2M BPK BTK C7orf76 CAGA CAGB CALR CD14 CD36 CFAG CHUK CRTC DSS1 ERP57 ERP60 ESOP1 FGA FGB FGG FIP3 GP3B GP4 GRP58 HC2 HC3 HC8 HC9 HLA-5.4 HLA-6.0 HLA-6.2 HLA-A HLA-B HLA-C HLA-E HLA-F HLA-G HLA-H HLAA HLAB HLAC HLAE HLAF HLAG HLAH HMG1 HMGB1 HSPC IFI5111 IKBKB IKBKG IKKA IKKB KIAA0012 KIAA0072 KIAA0077 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY LY96 MAL MB1 MCB1 MD2 MECL1 MIP224 MOV34L MRP14 MRP8 MSS1 MYD88 NEMO NGS17 NU PDIA3 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSF1 PSF2 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RING10 RING11 RING12 RING4 RPS27A S100A S100A1 S100A8 S100A9 SEC22B SEC22L1 SEC61A SEC61A1 SEC61A2 SEC61B SEC61G SEM1 SHFDG1 SHFM1 SNAP23 STX4 STX4A SUG1 SUG2 SYB3 TAP1 TAP2 TAPA TAPBP TBP1 TBP7 TCF16 TIL4 TIRAP TLR1 TLR2 TLR4 TLR6 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VAMP3 VAMP8 X Y Y1 Y2 Y3 Z mip porB	Homo sapiens (human)
Defective ABCB4 causes PFIC3, ICP3 and GBD1	Phosphatidylcholine translocator ABCB4	P21439	ABCB4 MDR3 PGY3	Homo sapiens (human)
Defective ABCB6 causes MCOPCB7	ATP-binding cassette sub-family B member 6	Q9NP58	ABCB6 MTABC3 PRP UMAT	Homo sapiens (human)
Heme degradation	ATP-binding cassette sub-family C member 2 Albumin Beta-glucuronidase Biliverdin reductase A Broad substrate specificity ATP-binding cassette transporter ABCG2 Fatty acid-binding protein, liver Flavin reductase (NADPH) Glutathione S-transferase A1 Heme oxygenase 1 Heme oxygenase 2 Multidrug resistance-associated protein 1 Solute carrier organic anion transporter family member 1B1 Solute carrier organic anion transporter family member 1B3 UDP-glucuronosyltransferase 1A1 UDP-glucuronosyltransferase 1A4	P02768 P07148 P08263 P09601 P22309 P22310 P30043 P30519 P33527 P53004 Q8VNV4 Q92887 Q9NPD5 Q9UNQ0 Q9Y6L6	ABCC1 ABCC2 ABCG2 ABCP ALB BCRP BCRP1 BLVR BLVRA BLVRB BVR CMOAT CMOAT1 CMRP FABP1 FABPL FLR GNT1 GSTA1 HMOX1 HMOX2 HO HO1 HO2 LST1 LST2 MRP MRP1 MRP2 MXR OATP1B1 OATP1B3 OATP2 OATP8 OATPC SCAN SLC21A6 SLC21A8 SLCO1B1 SLCO1B3 UGT1 UGT1A1 UGT1A4	Homo sapiens (human)
NFE2L2 regulating MDR associated enzymes	ATP-binding cassette sub-family C member 3 ATP-binding cassette sub-family F member 2 Broad substrate specificity ATP-binding cassette transporter ABCG2 CREB-binding protein Histone acetyltransferase p300 Multidrug resistance-associated protein 1 Nuclear factor erythroid 2-related factor 2 Transcription factor MafK	O15438 O60675 P33527 Q09472 Q16236 Q92793 Q9UG63 Q9UNQ0	ABCC1 ABCC3 ABCF2 ABCG2 ABCP BCRP BCRP1 CBP CMOAT2 CREBBP EP300 MAFK MLP2 MRP MRP1 MRP3 MXR NFE2L2 NRF2 P300	Homo sapiens (human)
Sphingolipid de novo biosynthesis	3-ketodihydrosphingosine reductase Broad substrate specificity ATP-binding cassette transporter ABCG2 Casein kinase I isoform gamma-2 Ceramide synthase 1 Ceramide synthase 2 Ceramide synthase 3 Ceramide synthase 4 Ceramide synthase 5 Ceramide synthase 6 Cytochrome b5 type B Fatty acid 2-hydroxylase Multidrug resistance-associated protein 1 ORM1-like protein 1 ORM1-like protein 2 ORM1-like protein 3 Oxysterol-binding protein 1 Phosphatidylcholine Phosphatidylcholine Protein phosphatase 1L Serine palmitoyltransferase 1 Serine palmitoyltransferase 2 Serine palmitoyltransferase 3 Serine palmitoyltransferase small subunit A Serine palmitoyltransferase small subunit B Serine/threonine-protein kinase D1 Serine/threonine-protein kinase D2 Serine/threonine-protein kinase D3 Sphingolipid delta(4)-desaturase DES1 Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 Sphingomyelin synthase-related protein 1 Sphingosine kinase 1 Sphingosine kinase 2 Sphingosine-1-phosphate transporter MFSD2B Sphingosine-1-phosphate transporter SPNS2 Vesicle-associated membrane protein-associated protein A Vesicle-associated membrane protein-associated protein B/C	A6NFX1 O15121 O15269 O15270 O43169 O94806 O95292 P22059 P27544 P33527 P78368 Q06136 Q15139 Q53FV1 Q5SGD2 Q6QHC5 Q6ZMG9 Q7L5A8 Q86VZ5 Q8IU89 Q8IVW8 Q8N138 Q8N5B7 Q8NFR3 Q8NHU3 Q969W0 Q96G23 Q96LT4 Q9BZL6 Q9HA82 Q9NRA0 Q9NUV7 Q9NYA1 Q9P0L0 Q9P0S3 Q9UNQ0	ABCC1 ABCG2 ABCP ADMP BCRP BCRP1 C14orf147 C14orf66 C20orf38 C3orf57 CERS1 CERS2 CERS3 CERS4 CERS5 CERS6 CK1G2 CSNK1G2 CYB5B CYB5M DEGS1 DEGS2 DES1 EPK2 FA2H FAAH FAXDC1 FVT1 KDSR KIAA0526 LAG1 LASS1 LASS2 LASS3 LASS4 LASS5 LASS6 LCB1 LCB2 MFSD2B MLD MOB MRP MRP1 MXR OMB5 ORMDL1 ORMDL2 ORMDL3 OSBP OSBP1 PKD PKD1 PKD2 PP2CE PPM1L PRKCM PRKCN PRKD1 PRKD2 PRKD3 SAMD8 SDR35C1 SGMS1 SGMS2 SK1 SK2 SMS1 SMS2 SPHK SPHK1 SPHK2 SPK SPNS2 SPTLC1 SPTLC2 SPTLC2L SPTLC3 SPTSSA SPTSSB SSSPTA SSSPTB TMEM23 TMSG1 UOG1 VAP33 VAPA VAPB	Homo sapiens (human)
Cytoprotection by HMOX1	3'-5' exoribonuclease HELZ2 Albumin Biliverdin reductase A CREB-binding protein Chromodomain-helicase-DNA-binding protein 9 Cytochrome c oxidase assembly protein COX11, mitochondrial Cytochrome c oxidase assembly protein COX14 Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial Cytochrome c oxidase assembly protein COX18, mitochondrial Cytochrome c oxidase assembly protein COX19 Cytochrome c oxidase assembly protein COX20, mitochondrial Cytochrome c oxidase subunit 1 Cytochrome c oxidase subunit 2 Cytochrome c oxidase subunit 3 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial Cytochrome c oxidase subunit 5A, mitochondrial Cytochrome c oxidase subunit 5B, mitochondrial Cytochrome c oxidase subunit 6A1, mitochondrial Cytochrome c oxidase subunit 6B1 Cytochrome c oxidase subunit 6C Cytochrome c oxidase subunit 7A-related protein, mitochondrial Cytochrome c oxidase subunit 7B, mitochondrial Cytochrome c oxidase subunit 7C, mitochondrial Cytochrome c oxidase subunit 8A, mitochondrial Cytochrome c oxidase subunit NDUFA4 Cytochrome c F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Fatty acid-binding protein, liver Flavin reductase (NADPH) Heme oxygenase 1 Heme oxygenase 2 Hemoglobin subunit alpha Hemoglobin subunit beta Histone deacetylase 3 Histone-arginine methyltransferase CARM1 Leucine-rich PPR motif-containing protein, mitochondrial Mediator of RNA polymerase II transcription subunit 1 Multidrug resistance-associated protein 1 NACHT, LRR and PYD domains-containing protein 3 Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Nuclear receptor coactivator 6 Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 Paired amphipathic helix protein Sin3a Peroxisome proliferator-activated receptor alpha Protein SCO1 homolog, mitochondrial Protein SCO2 homolog, mitochondrial Protein-tyrosine kinase 6 Retinoic acid receptor RXR-alpha SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 Signal transducer and activator of transcription 3 Signal-transducing adaptor protein 2 Surfeit locus protein 1 Thioredoxin-interacting protein Translational activator of cytochrome c oxidase 1 Trimethylguanosine synthase	O00483 O14548 O15379 O43819 O60907 O75376 O75880 P00395 P00403 P00414 P02768 P07148 P09601 P09669 P10176 P10606 P12074 P13073 P14854 P15954 P19793 P20674 P24311 P30043 P30519 P33527 P40763 P42704 P53004 P68871 P69905 P99999 Q07869 Q13882 Q14686 Q15526 Q15596 Q15648 Q15788 Q3L8U1 Q49B96 Q5RI15 Q6STE5 Q86X55 Q8N8Q8 Q92793 Q96I36 Q96P20 Q96RS0 Q96ST3 Q9BSH4 Q9BYK8 Q9BZK7 Q9H3M7 Q9P0S2 Q9UGK3 Q9Y618 Q9Y6N1	ABCC1 AIB3 ALB APRF ARC205 BAF60C BHLHE74 BHLHE75 BKS BLVR BLVRA BLVRB BRK BVR C12orf62 C14orf112 C1orf7 CARM1 CBP CCDC44 CHD9 CIAS1 COI COII COIII COX11 COX14 COX16 COX18 COX19 COX2 COX20 COX4 COX4I1 COX5A COX5B COX6A1 COX6AL COX6B COX6B1 COX6C COX7A2L COX7AR COX7B COX7C COX7RP COX8 COX8A COX8L COXI COXII COXIII CREBBP CRSP1 CRSP200 CTG26 CYC CYCS DRIP205 DRIP230 FABP1 FABPL FAM36A FLR HBA1 HBA2 HBB HCA137 HDAC3 HELZ2 HMOX1 HMOX2 HO HO1 HO2 IRA1 KIAA0181 KIAA0308 KIAA1047 KIAA1769 KISH2 LRP130 LRPPRC MED1 MRP MRP1 MT-CO1 MT-CO2 MT-CO3 MTCO1 MTCO2 MTCO3 NALP3 NCOA1 NCOA2 NCOA6 NCOA6IP NCOR1 NCOR2 NDUFA4 NLRP3 NR1C1 NR2B1 OXA1L2 PBP PIMT PPAR PPARA PPARBP PPARGBP PRIC285 PRIC320 PRMT4 PTK6 PYPAF1 RAP250 RB18A RXRA SCAN SCO1 SCO2 SCOD1 SIN3A SMARCD3 SRC1 SRC2 STAP2 STAT3 SURF-1 SURF1 TACO1 TBL1 TBL1X TBL1XR1 TBLR1 TGS1 TIF2 TRAP220 TRBP TRIP2 TXNIP VDUP1	Homo sapiens (human)
Synthesis of Leukotrienes (LT) and Eoxins (EX)	Arachidonate 5-lipoxygenase-activating protein Cytochrome P450 4A11 Cytochrome P450 4A22 Cytochrome P450 4B1 Cytochrome P450 4F11 Cytochrome P450 4F2 Cytochrome P450 4F3 Cytochrome P450 4F8 Dipeptidase 1 Dipeptidase 2 Dipeptidase 3 Glutathione hydrolase 1 proenzyme Glutathione hydrolase 5 proenzyme Leukotriene A-4 hydrolase Leukotriene C4 synthase MAP kinase-activated protein kinase 2 Multidrug resistance-associated protein 1 Polyunsaturated fatty acid 5-lipoxygenase Polyunsaturated fatty acid lipoxygenase ALOX15 Prostaglandin reductase 1 Ultra-long-chain fatty acid omega-hydroxylase	P09917 P09960 P13584 P16050 P16444 P19440 P20292 P33527 P36269 P49137 P78329 P98187 Q02928 Q08477 Q14914 Q16873 Q5TCH4 Q6NT55 Q9H4A9 Q9H4B8 Q9HBI6	ABCC1 ALOX15 ALOX5 ALOX5AP CYP4A11 CYP4A2 CYP4A22 CYP4B1 CYP4F11 CYP4F2 CYP4F22 CYP4F3 CYP4F8 DPEP1 DPEP2 DPEP3 FLAP GGT GGT1 GGT5 GGTLA1 LOG15 LOG5 LTA4 LTA4H LTB4DH LTB4H LTC4S MAPKAPK2 MDP MRP MRP1 PTGR1 RDP	Homo sapiens (human)
Aspirin ADME	ATP-binding cassette sub-family C member 2 ATP-binding cassette sub-family C member 3 Acyl-coenzyme A synthetase ACSM2A, mitochondrial Acyl-coenzyme A synthetase ACSM2B, mitochondrial Acyl-coenzyme A synthetase ACSM4, mitochondrial Acyl-coenzyme A synthetase ACSM5, mitochondrial Albumin Basigin Cholinesterase Cocaine esterase Cytochrome P450 2C19 Cytochrome P450 2C8 Cytochrome P450 2C9 Cytochrome P450 2D6 Cytochrome P450 2E1 Cytochrome P450 3A4 Glycine N-acyltransferase-like protein 1 Glycine N-acyltransferase-like protein 2 Glycine N-acyltransferase-like protein 3 Glycine N-acyltransferase Liver carboxylesterase 1 Monocarboxylate transporter 1 Solute carrier family 22 member 7 UDP-glucuronosyltransferase 1-6 UDP-glucuronosyltransferase 1A1 UDP-glucuronosyltransferase 1A3 UDP-glucuronosyltransferase 1A4 UDP-glucuronosyltransferase 1A5 UDP-glucuronosyltransferase 1A7 UDP-glucuronosyltransferase 1A8 UDP-glucuronosyltransferase 1A9 UDP-glucuronosyltransferase 2A1 UDP-glucuronosyltransferase 2A2 UDP-glucuronosyltransferase 2A3 UDP-glucuronosyltransferase 2B10 UDP-glucuronosyltransferase 2B11 UDP-glucuronosyltransferase 2B15 UDP-glucuronosyltransferase 2B17 UDP-glucuronosyltransferase 2B28 UDP-glucuronosyltransferase 2B4 UDP-glucuronosyltransferase 2B7 UDP-glucuronosyltransferase 3A1 UDP-glucuronosyltransferase 3A2	O00748 O15438 O60656 O75310 O75795 P02768 P05181 P06133 P06276 P08684 P0C7M7 P0DTE4 P0DTE5 P10632 P10635 P11712 P16662 P19224 P22309 P22310 P23141 P33261 P35503 P35504 P35613 P36537 P53985 P54855 Q08AH3 Q3SY77 Q5SZD4 Q68CK6 Q6IB77 Q6NUN0 Q6NUS8 Q6UWM9 Q8WU03 Q92887 Q969I3 Q9BY64 Q9HAW7 Q9HAW9 Q9Y694	ABCC2 ABCC3 ACGNAT ACSM2 ACSM2A ACSM2B ACSM4 ACSM5 ALB BCHE BSG C6orf140 CAT CES1 CES2 CHE1 CMOAT CMOAT1 CMOAT2 CMRP CYP2C10 CYP2C19 CYP2C8 CYP2C9 CYP2D6 CYP2DL1 CYP2E CYP2E1 CYP3A3 CYP3A4 GAT GLYAT GLYATL1 GLYATL2 GLYATL3 GNAT GNT1 ICE MACS2 MACS3 MCT1 MLP2 MRP2 MRP3 NLT OAT2 SES1 SLC16A1 SLC22A7 UGT1 UGT1A1 UGT1A3 UGT1A4 UGT1A5 UGT1A6 UGT1A7 UGT1A8 UGT1A9 UGT2A1 UGT2A2 UGT2A3 UGT2B10 UGT2B11 UGT2B15 UGT2B17 UGT2B28 UGT2B4 UGT2B7 UGT2B8 UGT3A1 UGT3A2 UGTB2B9	Homo sapiens (human)
Defective ABCC2 causes DJS	ATP-binding cassette sub-family C member 2	Q92887	ABCC2 CMOAT CMOAT1 CMRP MRP2	Homo sapiens (human)
Azathioprine ADME	ATP-binding cassette sub-family C member 4 ATP-binding cassette sub-family C member 5 Equilibrative nucleoside transporter 1 Equilibrative nucleoside transporter 2 GMP synthase [glutamine-hydrolyzing] Glutathione S-transferase A1 Glutathione S-transferase A2 Glutathione S-transferase Mu 1 Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Guanylate kinase Hypoxanthine-guanine phosphoribosyltransferase Inosine-5'-monophosphate dehydrogenase 1 Inosine-5'-monophosphate dehydrogenase 2 Nucleoside diphosphate kinase A Nucleoside diphosphate kinase B Nucleotide triphosphate diphosphatase NUDT15 Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Sodium/nucleoside cotransporter 2 Solute carrier family 28 member 3 Thiopurine S-methyltransferase Xanthine dehydrogenase/oxidase	O15439 O15440 O43868 P00492 P08263 P09210 P09488 P12268 P15498 P15531 P20839 P22392 P47989 P49915 P51580 P52735 P63000 Q14542 Q16774 Q99808 Q9HAS3 Q9NV35 Q9UKW4	ABCC4 ABCC5 CNT2 CNT3 DER12 ENT1 ENT2 GMK GMPK GMPS GST1 GST2 GSTA1 GSTA2 GSTM1 GUK1 HNP36 HPRT HPRT1 IMPD1 IMPD2 IMPDH1 IMPDH2 MOATB MRP4 MRP5 MTH2 NDPKA NM23 NM23B NME1 NME2 NUDT15 RAC1 SLC28A2 SLC28A3 SLC29A1 SLC29A2 TC25 TPMT VAV VAV1 VAV2 VAV3 XDH XDHA	Homo sapiens (human)
Hyaluronan biosynthesis and export	ATP-binding cassette sub-family C member 5 Cell migration-inducing and hyaluronan-binding protein Hyaluronan synthase 1 Hyaluronan synthase 2 Hyaluronan synthase 3	O00219 O15440 Q8WUJ3 Q92819 Q92839	ABCC5 CEMIP HAS HAS1 HAS2 HAS3 HYBID KIAA1199 MRP5	Homo sapiens (human)	G35674CY
Defective ABCC6 causes PXE	ATP-binding cassette sub-family C member 6	O95255	ABCC6 ARA MRP6	Homo sapiens (human)
Ub-specific processing proteases	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Androgen receptor Antiviral innate immune response receptor RIG-I Ataxin-7 Axin-1 Axin-2 Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 Beclin-1 Beta-2 adrenergic receptor Beta-arrestin-1 Beta-arrestin-2 CAAX prenyl protease 2 Cell division cycle protein 20 homolog Cellular tumor antigen p53 Centriolar coiled-coil protein of 110 kDa Claspin Cyclin-A1 Cyclin-A2 Cystic fibrosis transmembrane conductance regulator DNA damage-binding protein 2 DNA polymerase beta E3 ubiquitin-protein ligase Mdm2 E3 ubiquitin-protein ligase RNF123 E3 ubiquitin-protein ligase RNF128 E3 ubiquitin-protein ligase RNF146 E3 ubiquitin-protein ligase SIAH2 E3 ubiquitin-protein ligase SMURF2 Forkhead box protein O4 Hepatocyte growth factor-regulated tyrosine kinase substrate Histone H2A type 1-A Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-H Histone H2A type 1-J Histone H2A type 1 Histone H2A type 2-A Histone H2A type 2-B Histone H2A type 2-C Histone H2A type 3 Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 2-F Histone H2B type 3-B Histone acetyltransferase KAT2A Hypoxia-inducible factor 1-alpha Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4 Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 8 Insulin-degrading enzyme Interferon-induced helicase C domain-containing protein 1 Interleukin-33 Kelch-like ECH-associated protein 1 M-phase inducer phosphatase 1 Methionine adenosyltransferase 2 subunit beta Mitochondrial Rho GTPase 1 Mitochondrial import receptor subunit TOM20 homolog Mitochondrial import receptor subunit TOM70 Mitochondrial ubiquitin ligase activator of NFKB 1 Mitogen-activated protein kinase kinase kinase 7 Mothers against decapentaplegic homolog 1 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Mothers against decapentaplegic homolog 7 Myc proto-oncogene protein NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Peptidyl-prolyl cis-trans isomerase FKBP8 Peptidyl-tRNA hydrolase 2, mitochondrial Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Poly [ADP-ribose] polymerase tankyrase-1 Poly [ADP-ribose] polymerase tankyrase-2 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein Mdm4 Receptor-interacting serine/threonine-protein kinase 1 RuvB-like 1 S-phase kinase-associated protein 2 Signal transducing adapter molecule 2 Sin3 histone deacetylase corepressor complex component SDS3 Sorting nexin-3 TGF-beta receptor type-1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TNF receptor-associated factor 2 TNF receptor-associated factor 6 Trans-acting T-cell-specific transcription factor GATA-3 Transcription initiation factor TFIID subunit 10 Transcription initiation factor TFIID subunit 9B Transcriptional adapter 2-beta Transcriptional adapter 3 Transformation/transcription domain-associated protein Ubiquitin carboxyl-terminal hydrolase 10 Ubiquitin carboxyl-terminal hydrolase 11 Ubiquitin carboxyl-terminal hydrolase 12 Ubiquitin carboxyl-terminal hydrolase 13 Ubiquitin carboxyl-terminal hydrolase 14 Ubiquitin carboxyl-terminal hydrolase 15 Ubiquitin carboxyl-terminal hydrolase 16 Ubiquitin carboxyl-terminal hydrolase 17-like protein 10 Ubiquitin carboxyl-terminal hydrolase 17-like protein 11 Ubiquitin carboxyl-terminal hydrolase 17-like protein 12 Ubiquitin carboxyl-terminal hydrolase 17-like protein 13 Ubiquitin carboxyl-terminal hydrolase 17-like protein 15 Ubiquitin carboxyl-terminal hydrolase 17-like protein 17 Ubiquitin carboxyl-terminal hydrolase 17-like protein 18 Ubiquitin carboxyl-terminal hydrolase 17-like protein 19 Ubiquitin carboxyl-terminal hydrolase 17-like protein 1 Ubiquitin carboxyl-terminal hydrolase 17-like protein 20 Ubiquitin carboxyl-terminal hydrolase 17-like protein 21 Ubiquitin carboxyl-terminal hydrolase 17-like protein 22 Ubiquitin carboxyl-terminal hydrolase 17-like protein 24 Ubiquitin carboxyl-terminal hydrolase 17-like protein 3 Ubiquitin carboxyl-terminal hydrolase 17-like protein 5 Ubiquitin carboxyl-terminal hydrolase 17 Ubiquitin carboxyl-terminal hydrolase 19 Ubiquitin carboxyl-terminal hydrolase 20 Ubiquitin carboxyl-terminal hydrolase 21 Ubiquitin carboxyl-terminal hydrolase 22 Ubiquitin carboxyl-terminal hydrolase 24 Ubiquitin carboxyl-terminal hydrolase 25 Ubiquitin carboxyl-terminal hydrolase 26 Ubiquitin carboxyl-terminal hydrolase 28 Ubiquitin carboxyl-terminal hydrolase 2 Ubiquitin carboxyl-terminal hydrolase 30 Ubiquitin carboxyl-terminal hydrolase 33 Ubiquitin carboxyl-terminal hydrolase 34 Ubiquitin carboxyl-terminal hydrolase 37 Ubiquitin carboxyl-terminal hydrolase 3 Ubiquitin carboxyl-terminal hydrolase 42 Ubiquitin carboxyl-terminal hydrolase 44 Ubiquitin carboxyl-terminal hydrolase 47 Ubiquitin carboxyl-terminal hydrolase 48 Ubiquitin carboxyl-terminal hydrolase 49 Ubiquitin carboxyl-terminal hydrolase 4 Ubiquitin carboxyl-terminal hydrolase 5 Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin carboxyl-terminal hydrolase 8 Ubiquitin carboxyl-terminal hydrolase 9X Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin recognition factor in ER-associated degradation protein 1 Ubiquitin thioesterase OTUB1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Ubl carboxyl-terminal hydrolase 18 Voltage-dependent anion-selective channel protein 1 Voltage-dependent anion-selective channel protein 2 Voltage-dependent anion-selective channel protein 3 WD repeat-containing protein 20 WD repeat-containing protein 48	A5LHX3 A6NCW0 A6NCW7 A8MUK1 C9J2P7 C9JJH3 C9JLJ4 C9JPN9 C9JVI0 D6R901 D6R9N7 D6RA61 D6RBQ6 D6RCP7 D6RJB6 O00231 O00232 O00233 O00487 O14818 O14964 O15105 O15151 O15169 O15265 O43242 O43255 O43303 O43318 O60493 O60814 O75317 O75528 O75604 O75832 O75886 O94826 O94966 O95271 O95760 O95786 P01106 P04637 P04908 P06746 P06899 P07550 P0C0S8 P0C7I0 P0CG47 P0CG48 P10275 P13569 P14735 P17980 P20248 P20618 P20671 P21796 P23527 P23771 P25786 P25787 P25788 P25789 P25963 P28062 P28065 P28066 P28070 P28072 P28074 P30304 P32121 P33778 P35998 P36897 P40306 P40818 P43686 P45880 P45974 P48556 P49407 P49720 P49721 P51665 P51784 P54578 P55036 P58876 P60484 P60896 P60900 P61289 P62191 P62195 P62333 P62807 P62979 P62987 P78396 P84022 P98177 Q00987 Q06323 Q0WX57 Q12834 Q12933 Q12962 Q13107 Q13200 Q13309 Q13485 Q13489 Q13490 Q13546 Q14145 Q14318 Q14457 Q14694 Q14997 Q15008 Q15388 Q15750 Q15796 Q15797 Q16186 Q16401 Q16665 Q16777 Q16778 Q5QNW6 Q5XPI4 Q6FI13 Q6R6M4 Q70CQ1 Q70CQ2 Q70CQ3 Q7L7L0 Q7RTZ2 Q86T82 Q86TJ2 Q86UV5 Q8IUE6 Q8IXI2 Q8N257 Q8TAA3 Q8TAF3 Q8TBZ3 Q8TEB7 Q8TEY7 Q92466 Q92530 Q92830 Q92890 Q92995 Q93008 Q93009 Q93077 Q93079 Q969V5 Q96A08 Q96FW1 Q96K76 Q96KK5 Q96QV6 Q96RU2 Q99436 Q99460 Q99877 Q99878 Q99879 Q99880 Q9BXU7 Q9BYX4 Q9H0E7 Q9H2K2 Q9H7L9 Q9H9J4 Q9HAU4 Q9HAW4 Q9HBM6 Q9NQC7 Q9NTX7 Q9NZL9 Q9UHP3 Q9UK80 Q9UL46 Q9UMW8 Q9UNM6 Q9UPT9 Q9UPU5 Q9Y256 Q9Y265 Q9Y277 Q9Y2K6 Q9Y2T1 Q9Y3E5 Q9Y4A5 Q9Y4E8 Q9Y4K3 Q9Y5T5 Q9Y6I4 Q9Y6K9	ABCC7 ADA2B ADA3 ADRB2 ADRB2R ADRM1 AFX AFX1 ALK5 API1 API2 AR ARB2 ARHT1 ARR1 ARR2 ARRB1 ARRB2 ATXN7 AXIN AXIN1 AXIN2 B2AR BECN1 BHLHE39 BHLHE78 BIRC2 BIRC3 BIT1 BSP1 C1orf166 C7orf76 C9orf26 CCN1 CCNA CCNA1 CCNA2 CCP110 CDC20 CDC25A CEP110 CFTR CLSPN CP110 CYLD CYLD1 DDB2 DDX58 DFFRX DHTR DPC4 DSS1 DUB3 FACE2 FAM FBXL1 FIP3 FKBP38 FKBP8 FOXO4 GATA3 GCN5 GCN5L2 GIDE GP110 GT197 H2AC1 H2AC11 H2AC12 H2AC13 H2AC14 H2AC15 H2AC16 H2AC17 H2AC18 H2AC19 H2AC20 H2AC21 H2AC25 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFC H2AFD H2AFE H2AFG H2AFI H2AFL H2AFM H2AFN H2AFO H2AFP H2AFQ H2AFR H2AW H2BC1 H2BC10 H2BC11 H2BC12 H2BC13 H2BC14 H2BC15 H2BC17 H2BC18 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFT H2BU1 HAUSP HBP HC2 HC3 HC8 HC9 HGS HIF1A HIRIP1 HIRIP2 HIST1H2AA HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AG HIST1H2AH HIST1H2AI HIST1H2AJ HIST1H2AK HIST1H2AL HIST1H2AM HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AB HIST2H2AC HIST2H2BE HIST2H2BF HIST3H2A HIST3H2BB HRS HSPC IDE IFI5111 IFIH1 IKBA IKBKG IL1F11 IL33 INO80H INRF2 ISG43 ISOT ISOT3 KAT2A KEAP1 KIAA0016 KIAA0055 KIAA0072 KIAA0077 KIAA0107 KIAA0132 KIAA0190 KIAA0419 KIAA0529 KIAA0570 KIAA0719 KIAA0729 KIAA0849 KIAA0891 KIAA1003 KIAA1057 KIAA1063 KIAA1097 KIAA1449 KIAA1515 KIAA1594 KLHL19 KPC1 LMP10 LMP2 LMP7 LMPX LMPY LSFR3A MAD3 MADH1 MADH2 MADH3 MADH4 MADH7 MADH8 MADR1 MADR2 MAP3K7 MAP3K7IP1 MAPL MAT2B MB1 MCB1 MDA5 MDM2 MDM4 MDMX MECL1 MIHB MIHC MIP224 MLLT7 MMAC1 MOP1 MOV34L MSS1 MUL1 MULAN MYC NEMO NFHEV NFKBI NFKBIA NMP238 NR3C4 NU OTB1 OTU1 OTUB1 P53 PAF400 PARP5A PARP5B PARPL PASD8 PFAAP4 POH1 POLB PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 PTEN PTH2 PTRH2 RCE1 RCE1A RCE1B RH116 RHOT1 RIGI RING10 RING12 RIP RIP1 RIPK1 RNF123 RNF128 RNF146 RNF218 RNF48 RNF49 RNF85 RPS27A RUVBL1 SAP45 SCA7 SDS3 SEM1 SHFDG1 SHFM1 SIAH2 SKP2 SKR4 SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 SMURF2 SNX3 STAM2 SUDS3 SUG1 SUG2 TAB1 TADA2B TADA3 TADA3L TAF10 TAF2A TAF2H TAF9B TAF9L TAFII30 TAK1 TANK2 TBP1 TBP7 TEP1 TGFBR1 TGR TGT TIN1 TINF1 TIP49 TIP49A TNKL TNKS TNKS1 TNKS2 TOM70 TOMM20 TOMM70 TOMM70A TP53 TRAF2 TRAF6 TRAP2 TRAP3 TRRAP TSH2B UAF1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBH1 UBP41 UBPY UFD1 UFD1L UHX1 UNP UNPH USP10 USP11 USP12 USP12L1 USP13 USP14 USP15 USP16 USP17 USP17B USP17F USP17H USP17I USP17J USP17K USP17L USP17L1 USP17L10 USP17L11 USP17L12 USP17L13 USP17L15 USP17L17 USP17L18 USP17L19 USP17L1P USP17L2 USP17L20 USP17L21 USP17L22 USP17L24 USP17L25 USP17L26 USP17L27 USP17L28 USP17L29 USP17L3 USP17L30 USP17L4 USP17L5 USP17L8 USP17M USP18 USP19 USP2 USP20 USP21 USP22 USP23 USP24 USP25 USP26 USP28 USP3 USP30 USP31 USP33 USP34 USP37 USP3L USP4 USP42 USP44 USP47 USP48 USP49 USP5 USP7 USP8 USP9 USP9X VDAC VDAC1 VDAC2 VDAC3 VDU1 VDU2 WDR20 WDR48 X Y Y2 Z ZMYND9	Homo sapiens (human)
Late endosomal microautophagy	ADP-ribosylation factor-like protein 13B Centrin-1 Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4a Charged multivesicular body protein 4b Charged multivesicular body protein 4c Charged multivesicular body protein 6 Charged multivesicular body protein 7 Cystic fibrosis transmembrane conductance regulator Heat shock cognate 71 kDa protein Hemoglobin subunit beta Histone deacetylase 6 Intraflagellar transport protein 88 homolog Multivesicular body subunit 12A Multivesicular body subunit 12B Parkinson disease protein 7 Pericentrin Perilipin-2 Perilipin-3 Polyubiquitin-B Polyubiquitin-C Ribonuclease pancreatic Tumor susceptibility gene 101 protein Ubiquitin-associated protein 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Vacuolar protein sorting-associated protein 28 homolog Vacuolar protein sorting-associated protein 37A Vacuolar protein sorting-associated protein 37B Vacuolar protein sorting-associated protein 37C Vacuolar protein sorting-associated protein 37D	A5D8V6 O43633 O60664 O95613 P07998 P0CG47 P0CG48 P11142 P13569 P62979 P62987 P68871 Q12798 Q13099 Q3SXY8 Q86XT2 Q8NEZ2 Q8WUX9 Q96CF2 Q96EY5 Q96FZ7 Q99497 Q99541 Q99816 Q9BY43 Q9H444 Q9H7P6 Q9H9H4 Q9NZ09 Q9UBN7 Q9UK41 Q9UQN3 Q9Y3E7	ABCC7 ADFP ARL13B ARL2L1 BC2 C14orf123 C20orf178 C9orf28 CEN1 CETN CETN1 CFBP CFTR CGI149 CHMP2 CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP6 CHMP7 FAM125A FAM125B HBB HCRP1 HDAC6 HSC70 HSP73 HSPA10 HSPA8 IFT88 KIAA0402 KIAA0901 M6PRBP1 MVB12A MVB12B NEDF PARK7 PCNT PCNT2 PLIN2 PLIN3 PML39 RIB1 RNASE1 RNS1 RPS27A SHAX1 SHAX2 SHAX3 TG737 TIP47 TSG101 TTC10 UBA52 UBA80 UBAP1 UBB UBC UBCEP1 UBCEP2 VPS20 VPS24 VPS28 VPS37A VPS37B VPS37C VPS37D WBSCR24	Homo sapiens (human)
Chaperone Mediated Autophagy	ADP-ribosylation factor-like protein 13B Centrin-1 Cystic fibrosis transmembrane conductance regulator Elongation factor 1-alpha 1 Glial fibrillary acidic protein Heat shock cognate 71 kDa protein Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Hemoglobin subunit beta Histone deacetylase 6 Intraflagellar transport protein 88 homolog Lysosome-associated membrane glycoprotein 2 Parkinson disease protein 7 Pericentrin Perilipin-2 Perilipin-3 Polyubiquitin-B Polyubiquitin-C Ribonuclease pancreatic Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O60664 O95613 P07900 P07998 P08238 P0CG47 P0CG48 P11142 P13473 P13569 P14136 P62979 P62987 P68104 P68871 Q12798 Q13099 Q3SXY8 Q99497 Q99541 Q9UBN7	ABCC7 ADFP ARL13B ARL2L1 CEN1 CETN CETN1 CFTR EEF1A EEF1A1 EF1A GFAP HBB HDAC6 HSC70 HSP73 HSP90A HSP90AA1 HSP90AB1 HSP90B HSPA10 HSPA8 HSPC1 HSPC2 HSPC3 HSPCA HSPCB IFT88 KIAA0402 KIAA0901 LAMP2 LENG7 M6PRBP1 PARK7 PCNT PCNT2 PLIN2 PLIN3 RIB1 RNASE1 RNS1 RPS27A TG737 TIP47 TTC10 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
RHOQ GTPase cycle	ADP-ribosylation factor-like protein 13B ARF GTPase-activating protein GIT1 ARF GTPase-activating protein GIT2 Actin nucleation-promoting factor WASL Caveolin-1 Cdc42 effector protein 1 Cdc42 effector protein 2 Cdc42 effector protein 3 Cdc42 effector protein 4 Cdc42-interacting protein 4 Cell division control protein 42 homolog Copine-8 Cystic fibrosis transmembrane conductance regulator DEP domain-containing protein 1B Formin-binding protein 1 Gap junction alpha-1 protein Glucose-fructose oxidoreductase domain-containing protein 1 Golgi-associated PDZ and coiled-coil motif-containing protein Intersectin-1 Junction plakoglobin MAGUK p55 subfamily member 7 Metalloreductase STEAP3 NEDD4-like E3 ubiquitin-protein ligase WWP2 Neutral amino acid transporter B(0) Obscurin Oligophrenin-1 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Pleckstrin homology domain-containing family G member 3 Protein diaphanous homolog 3 Protein scribble homolog Ragulator complex protein LAMTOR1 Ras GTPase-activating-like protein IQGAP1 Ras GTPase-activating-like protein IQGAP3 Ras-related protein Rab-7a Rho GTPase-activating protein 17 Rho GTPase-activating protein 1 Rho GTPase-activating protein 21 Rho GTPase-activating protein 26 Rho GTPase-activating protein 32 Rho GTPase-activating protein 33 Rho GTPase-activating protein 35 Rho GTPase-activating protein 5 Rho GTPase-activating protein 7 Rho GTPase-activating protein SYDE1 Rho guanine nucleotide exchange factor 7 Rho guanine nucleotide exchange factor 9 Rho-related GTP-binding protein RhoQ SLIT-ROBO Rho GTPase-activating protein 2 Serine/threonine-protein kinase MRCK alpha Serine/threonine-protein kinase MRCK beta Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 4 Sodium bicarbonate cotransporter 3 Stomatin Synaptosomal-associated protein 23 Transferrin receptor protein 1 Vang-like protein 1 Vesicle-associated membrane protein 3	A1L390 A7KAX9 O00161 O00308 O00401 O14559 O14613 O43307 O60890 O75044 O96013 P02786 P13569 P14923 P17081 P17302 P27105 P46940 P51149 P60953 Q00587 Q03135 Q07960 Q13017 Q13153 Q13177 Q14155 Q14160 Q14161 Q15642 Q15758 Q15811 Q15836 Q3SXY8 Q5T2T1 Q5T5U3 Q5VST9 Q5VT25 Q658P3 Q68EM7 Q6IAA8 Q6ZW31 Q86VI3 Q86YQ8 Q8TAA9 Q8TCU6 Q8WUY9 Q96QB1 Q96RU3 Q9H3Q1 Q9HD26 Q9NRY4 Q9NSV4 Q9NXC2 Q9UKI2 Q9UNA1 Q9Y2X7 Q9Y5S2 Q9Y6M7	ABCC7 ARHDH9 ARHGAP1 ARHGAP10 ARHGAP17 ARHGAP21 ARHGAP26 ARHGAP32 ARHGAP33 ARHGAP34 ARHGAP35 ARHGAP5 ARHGAP7 ARHGEF7 ARHGEF9 ARHQ ARL13B ARL2L1 ASCT2 BND7 BORG1 BORG2 BORG4 BORG5 BT C11orf59 C6orf114 CAL CAV CAV1 CDC42 CDC42BPA CDC42BPB CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 CDC42GAP CEP1 CEP2 CEP3 CEP4 CFTR CIP4 COOL1 CPNE8 CRIB1 CTNNG DEPDC1B DIAP3 DIAPH3 DLC1 DP3 EPB72 FBP17 FIG FNBP1 FNBP2 GFOD1 GIT1 GIT2 GJA1 GJAL GOPC GRAF GRF1 GRIT GRLF1 IQGAP1 IQGAP3 ITSN ITSN1 JUP KIAA0051 KIAA0142 KIAA0147 KIAA0148 KIAA0424 KIAA0451 KIAA0456 KIAA0554 KIAA0599 KIAA0621 KIAA0712 KIAA1124 KIAA1142 KIAA1415 KIAA1424 KIAA1556 KIAA1639 KIAA1722 KIAA1723 LAMTOR1 LAP4 M7V1 MPP7 MSE55 NBC2 NBC2B NBC3 NBCn1 OBSCN OPHN1 OPHN1L P190A P85SPR PAK1 PAK2 PAK3BP PAK4 PDRO PIXB PLEKHG3 PREX1 RAB7 RAB7A RASL7A RDR RDRC RHOGAP1 RHOGAP5 RHOQ RICH1 RICS SBC2 SCRB1 SCRIB SH3D1A SLC1A5 SLC4A6 SLC4A7 SNAP23 SNX26 SRGAP2 SRGAP2A STARD12 STB2 STEAP3 STOM STOT STP SYB3 SYDE1 TC10 TCGAP TFRC TRIP10 TSAP6 VAMP3 VANGL1 VARTUL WASL WWP2 XTP8 p190ARHOGAP	Homo sapiens (human)
RHO GTPases regulate CFTR trafficking	Cystic fibrosis transmembrane conductance regulator Golgi-associated PDZ and coiled-coil motif-containing protein Rho-related GTP-binding protein RhoQ	P13569 P17081 Q9HD26	ABCC7 ARHQ CAL CFTR FIG GOPC RASL7A RHOQ TC10	Homo sapiens (human)
Aggrephagy	ADP-ribosylation factor-like protein 13B Centrin-1 Cystic fibrosis transmembrane conductance regulator Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic E3 ubiquitin-protein ligase parkin Heat shock factor protein 1 Heat shock protein HSP 90-alpha Histone deacetylase 6 Intraflagellar transport protein 88 homolog Parkinson disease protein 7 Pericentrin Polyubiquitin-B Polyubiquitin-C Transitional endoplasmic reticulum ATPase Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14576 O43237 O60260 O95613 P07900 P0CG47 P0CG48 P13569 P55072 P61088 P62979 P62987 P63167 Q00613 Q12798 Q13099 Q13404 Q13409 Q14204 Q3SXY8 Q96FJ2 Q99497 Q9UBN7 Q9Y6G9	ABCC7 ARL13B ARL2L1 BLU CEN1 CETN CETN1 CFTR CROC1 DHC1 DLC1 DLC2 DNCH1 DNCI1 DNCI2 DNCIC1 DNCIC2 DNCL DNCL1 DNCLC1 DNCLI1 DNCLI2 DNECL DYHC DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 HDAC6 HDLC1 HEL-220 HEL-S-70 HSF1 HSP90A HSP90AA1 HSPC1 HSPCA HSTF1 IFT88 KIAA0325 KIAA0402 KIAA0901 LIC2 PARK2 PARK7 PCNT PCNT2 PRKN RPS27A TG737 TTC10 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBE2N UBE2V UBE2V1 UEV1 VCP	Homo sapiens (human)
Defective CFTR causes cystic fibrosis	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cystic fibrosis transmembrane conductance regulator Derlin-1 Derlin-2 Derlin-3 E3 ubiquitin-protein ligase RNF185 E3 ubiquitin-protein ligase RNF5 Endoplasmic reticulum lectin 1 Erlin-1 Erlin-2 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein OS-9 Protein sel-1 homolog 1 Transitional endoplasmic reticulum ATPase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O43242 O75477 O75832 O94905 P0CG47 P0CG48 P13569 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P55072 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q06323 Q13200 Q13438 Q14997 Q15008 Q16401 Q8TAA3 Q92530 Q96DZ1 Q96GF1 Q96Q80 Q99436 Q99460 Q99942 Q9BUN8 Q9GZP9 Q9UBV2 Q9UL46 Q9UNM6	ABCC7 C10orf69 C22orf14 C2orf30 C7orf76 C8orf2 CFTR DER1 DER2 DER3 DERL1 DERL2 DERL3 DSS1 ERLEC1 ERLIN1 ERLIN2 FLANA G16 HC2 HC3 HC8 HC9 HEL-220 HEL-S-70 HSPC IFI5111 KE04 KEO4 KIAA0072 KIAA0077 KIAA0107 LLN2 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NG2 NU OS9 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RING10 RING12 RMA1 RNF185 RNF5 RPS27A SEL1L SEM1 SHFDG1 SHFM1 SPFH1 SPFH2 SUG1 SUG2 TBP1 TBP7 TRAP2 TSA305 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VCP X XTP3TPB Y Y2 Z	Homo sapiens (human)
ATP sensitive Potassium channels	ATP-binding cassette sub-family C member 8 ATP-binding cassette sub-family C member 9 ATP-sensitive inward rectifier potassium channel 11 ATP-sensitive inward rectifier potassium channel 8	O60706 Q09428 Q14654 Q15842	ABCC8 ABCC9 HRINS KCNJ11 KCNJ8 SUR SUR1 SUR2	Homo sapiens (human)
Regulation of insulin secretion	ATP-binding cassette sub-family C member 8 ATP-sensitive inward rectifier potassium channel 11 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Insulin Rap guanine nucleotide exchange factor 3 Rap guanine nucleotide exchange factor 4 S-adenosylhomocysteine hydrolase-like protein 1 Solute carrier family 2, facilitated glucose transporter member 1 Solute carrier family 2, facilitated glucose transporter member 2 Synaptosomal-associated protein 25 Synaptotagmin-5 Syntaxin-1A Syntaxin-binding protein 1 Vesicle-associated membrane protein 2 Voltage-dependent L-type calcium channel subunit alpha-1C Voltage-dependent L-type calcium channel subunit alpha-1D Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent L-type calcium channel subunit beta-3 Voltage-dependent P/Q-type calcium channel subunit alpha-1A Voltage-dependent R-type calcium channel subunit alpha-1E Voltage-dependent calcium channel subunit alpha-2/delta-2 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	O00445 O00555 O43865 O95398 P01308 P04899 P11166 P11168 P17612 P22612 P22694 P54284 P60880 P61764 P63027 P63096 Q01668 Q08289 Q09428 Q13936 Q14571 Q14573 Q14643 Q14654 Q15878 Q16623 Q8WZA2 Q9NY47	ABCC8 AHCYL1 CACH2 CACH3 CACH4 CACH6 CACN2 CACN3 CACN4 CACNA1A CACNA1C CACNA1D CACNA1E CACNA2D2 CACNB2 CACNB3 CACNL1A1 CACNL1A2 CACNL1A4 CACNL1A6 CACNLB2 CACNLB3 CCHL1A1 CCHL1A2 CGEF1 CGEF2 DCAL EPAC EPAC1 EPAC2 GLUT1 GLUT2 GNAI1 GNAI2 GNAI2B HRINS INS INSP3R1 IRBIT ITPR1 ITPR2 ITPR3 KCNJ11 KIAA0558 MYSB PKACA PRKACA PRKACB PRKACG RAPGEF3 RAPGEF4 SLC2A1 SLC2A2 SNAP SNAP25 STX1 STX1A STXBP1 SUR SUR1 SYB2 SYT5 UNC18A VAMP2 XPVKONA	Homo sapiens (human)	G58161NS
Defective ABCC8 can cause hypo- and hyper-glycemias	ATP-binding cassette sub-family C member 8 ATP-sensitive inward rectifier potassium channel 11	Q09428 Q14654	ABCC8 HRINS KCNJ11 SUR SUR1	Homo sapiens (human)
Ion homeostasis	ATP-binding cassette sub-family C member 9 ATP-sensitive inward rectifier potassium channel 11 Aspartyl/asparaginyl beta-hydroxylase Calcium release-activated calcium channel protein 1 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Cardiac phospholamban Chloride intracellular channel protein 2 FXYD domain-containing ion transport regulator 3 FXYD domain-containing ion transport regulator 4 FXYD domain-containing ion transport regulator 6 FXYD domain-containing ion transport regulator 7 Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Myotonin-protein kinase Nitric oxide synthase 1 Peptidyl-prolyl cis-trans isomerase FKBP1B Phospholemman Plasma membrane calcium-transporting ATPase 1 Plasma membrane calcium-transporting ATPase 2 Plasma membrane calcium-transporting ATPase 3 Plasma membrane calcium-transporting ATPase 4 Protein orai-2 Ryanodine receptor 1 Ryanodine receptor 2 Ryanodine receptor 3 S-adenosylhomocysteine hydrolase-like protein 1 Sarcolipin Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 Short transient receptor potential channel 1 Sodium/calcium exchanger 1 Sodium/calcium exchanger 2 Sodium/calcium exchanger 3 Sodium/potassium-transporting ATPase subunit alpha-1 Sodium/potassium-transporting ATPase subunit alpha-2 Sodium/potassium-transporting ATPase subunit alpha-3 Sodium/potassium-transporting ATPase subunit alpha-4 Sodium/potassium-transporting ATPase subunit beta-1 Sodium/potassium-transporting ATPase subunit beta-2 Sodium/potassium-transporting ATPase subunit beta-3 Sodium/potassium-transporting ATPase subunit gamma Sorcin Stromal interaction molecule 1 Triadin Troponin I, cardiac muscle cAMP-dependent protein kinase catalytic subunit alpha	O00168 O00631 O14983 O15247 O43865 O60706 P05023 P05026 P0DP23 P13637 P14415 P16615 P17612 P19429 P20020 P21817 P23634 P26678 P29475 P30626 P32418 P48995 P50993 P54709 P54710 P57103 P58549 P59646 P68106 Q01814 Q09013 Q12797 Q13061 Q13554 Q13555 Q13557 Q13586 Q13733 Q14571 Q14573 Q14643 Q14654 Q14802 Q15413 Q16720 Q92736 Q93084 Q96D31 Q96SN7 Q9H0Q3 Q9UPR5 Q9UQM7	ABCC9 AHCYL1 ASPH ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1AL2 ATP1B ATP1B1 ATP1B2 ATP1B3 ATP1C ATP1G1 ATP2A1 ATP2A2 ATP2A3 ATP2B ATP2B1 ATP2B2 ATP2B3 ATP2B4 BAH C7orf19 CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CBCIP2 CLIC2 CNC CRACM1 DCAL DM1PK DMPK FKBP12.6 FKBP1B FKBP1L FKBP9 FXYD1 FXYD2 FXYD3 FXYD4 FXYD6 FXYD7 GOK HBRR INSP3R1 IRBIT ITPR1 ITPR2 ITPR3 KCNJ11 KIAA0778 KIAA0968 KIAA1087 MAT8 MDPK MXRA1 NCX1 NCX2 NCX3 NOS1 ORAI1 ORAI2 OTK4 PKACA PLB PLM PLML PLN PMCA1 PMCA2 PRKACA RYDR RYR1 RYR2 RYR3 SLC8A1 SLC8A2 SLC8A3 SLN SRI STIM1 SUR2 TMEM142A TMEM142B TNNC1 TNNI3 TRDN TRP1 TRPC1 XPVKONA	Homo sapiens (human)
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome	ATP-binding cassette sub-family C member 9 ATP-sensitive inward rectifier potassium channel 11	O60706 Q14654	ABCC9 KCNJ11 SUR2	Homo sapiens (human)

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