GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **276 - 300** of **2090** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	GlyTouCan ID
Platelet degranulation	ATP-binding cassette sub-family C member 4 Adenylyl cyclase-associated protein 1 Albumin Alpha-1-acid glycoprotein 1 Alpha-1-acid glycoprotein 2 Alpha-1-antichymotrypsin Alpha-1-antitrypsin Alpha-1B-glycoprotein Alpha-2-HS-glycoprotein Alpha-2-antiplasmin Alpha-2-macroglobulin Alpha-actinin-1 Alpha-actinin-2 Alpha-actinin-4 Amyloid beta precursor like protein 2 Amyloid-beta precursor protein Annexin A5 Apolipoprotein A-I Beta-2-glycoprotein 1 Bromodomain and PHD finger-containing protein 3 CD109 antigen CD63 antigen CD9 antigen CYFIP-related Rac1 interactor B Calmodulin-1 Calumenin Cathepsin W Chitinase domain-containing protein 1 Clusterin Coagulation factor V Coagulation factor VIII Coagulation factor XIII A chain Cofilin-1 Complement factor D Endonuclease domain-containing 1 protein Endoplasmic reticulum chaperone BiP Extracellular matrix protein 1 Fermitin family homolog 3 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin Filamin-A Fructose-bisphosphate aldolase A GTP-binding protein 2 Galectin-3-binding protein Growth arrest-specific protein 6 Hepatocyte growth factor Histidine-rich glycoprotein Hsp90 co-chaperone Cdc37-like 1 Immunoglobulin superfamily containing leucine-rich repeat protein Insulin-like growth factor I Insulin-like growth factor II Integrin alpha-IIb Integrin beta-3 Inter-alpha-trypsin inhibitor heavy chain H3 Inter-alpha-trypsin inhibitor heavy chain H4 Intracellular hyaluronan-binding protein 4 Kallistatin Kininogen-1 LHFPL tetraspan subfamily member 2 protein Left-right determination factor 2 Lymphocyte antigen 6 complex locus protein G6f Lysosome-associated membrane glycoprotein 2 MICOS complex subunit MIC27 Melanoma-associated antigen D2 Mesencephalic astrocyte-derived neurotrophic factor Metalloproteinase inhibitor 1 Metalloproteinase inhibitor 3 Multimerin-1 NADH-cytochrome b5 reductase 1 NHL repeat-containing protein 2 Obg-like ATPase 1 P-selectin Peptidyl-prolyl cis-trans isomerase A Phosphatase and actin regulator 2 Plasma protease C1 inhibitor Plasminogen activator inhibitor 1 Plasminogen Platelet basic protein Platelet endothelial cell adhesion molecule Platelet factor 4 Platelet glycoprotein 4 Platelet-derived growth factor subunit B Pleckstrin Prenylcysteine oxidase-like Pro-epidermal growth factor Profilin-1 Prosaposin Protein FAM3C Protein disulfide-isomerase TMX3 Protocadherin-7 Putative beta-actin-like protein 3 Ras-related protein Rab-27B Retinoic acid receptor responder protein 2 SPARC Saccharopine dehydrogenase-like oxidoreductase Secreted phosphoprotein 24 Secretogranin-3 Selenoprotein P Serglycin Serotransferrin Sulfhydryl oxidase 1 Superoxide dismutase [Cu-Zn] Synaptotagmin-like protein 4 Syntaxin-binding protein 2 Talin-1 Testis-expressed protein 264 Tetranectin Thrombospondin-1 Thymosin beta-4 Titin Torsin-4A Transforming growth factor beta-1 proprotein Transforming growth factor beta-2 proprotein Transforming growth factor beta-3 proprotein Transgelin-2 Tubulin alpha-4A chain Vascular endothelial growth factor A, long form Vascular endothelial growth factor B Vascular endothelial growth factor C Vascular endothelial growth factor D Vesicle transport through interaction with t-SNAREs homolog 1B Vinculin Vitamin K-dependent protein S WD repeat-containing protein 1 von Willebrand factor	O00194 O00292 O00391 O14498 O15439 O43707 O43852 O43915 O60245 O75083 O75167 O94919 P00441 P00451 P00488 P00746 P00747 P01009 P01011 P01023 P01033 P01042 P01127 P01133 P01137 P01344 P02647 P02671 P02675 P02679 P02749 P02751 P02763 P02765 P02768 P02775 P02776 P02787 P04075 P04196 P04217 P04275 P05019 P05067 P05106 P05121 P05155 P05452 P07225 P07602 P07737 P07996 P08514 P08567 P08697 P08758 P08962 P09486 P0DP23 P10124 P10600 P10909 P11021 P12259 P12814 P13473 P14210 P15692 P16109 P16284 P16671 P18206 P19652 P21333 P21926 P23528 P29622 P35609 P35625 P37802 P49765 P49767 P49908 P55145 P56202 P61812 P62328 P62937 P68366 Q01518 Q06033 Q06481 Q08380 Q13103 Q13201 Q14393 Q14624 Q15833 Q16610 Q5JVS0 Q5SQ64 Q6UXV4 Q6YHK3 Q6ZUX7 Q7L3B6 Q86UX7 Q8NBF2 Q8NBM8 Q8NBX0 Q8WXD2 Q8WZ42 Q92520 Q96C24 Q96JJ7 Q99969 Q9BWS9 Q9BX10 Q9BYX7 Q9NTK5 Q9NUQ9 Q9NXH8 Q9UEU0 Q9UHQ9 Q9ULD4 Q9UNF1 Q9Y490 Q9Y6I9	A1BG A2M A4 AACT AAP AAT ABCC4 ACTBL3 ACTN1 ACTN2 ACTN4 AD1 AGP1 AGP2 AHSG ALB ALDA ALDOA ANX5 ANXA5 APLP2 APOA1 APOH APOJ APOOL APP APPL2 ARMET ARP AXLLG B2G1 BCG1 BDK BHPCDH BRPF3 C1IN C1NH C6orf21 C6orf56 C9orf167 CALM CALM1 CALU CAM CAM1 CAP CAP1 CD109 CD36 CD63 CD9 CDC37B CDC37L1 CFD CFL CFL1 CHID1 CLEC3B CLGI CLI CLU CPAMD5 CPAMD7 CTAP3 CTSW CXCL4 CXCL7 CXorf33 CYB5R1 CYPA CYRI CYRIB DF EBAF ECM ECM1 EGF EMILIN4 ENDOD1 ENX2 F13A F13A1 F5 F8 F8C F8VWF FAM121A FAM3C FAM49B FERMT3 FETUA FGA FGB FGG FIGF FLN FLN1 FLNA FN FN1 G6F GAS6 GLBA GMRP GP2B GP3A GP3B GP4 GPIA* GRMP GRP78 GTPBP2 GTPBP9 HABP4 HARC HGF HPTA HRG HSPA5 IBP1 IGF1 IGF2 IHRP ILEI ISLR ITGA2B ITGAB ITGB3 ITIH3 ITIH4 ITIHL1 KIAA0120 KIAA0206 KIAA0680 KIAA0830 KIAA1027 KIAA1286 KIAA1830 KIND3 KNG KNG1 KST KUB1 LAMP2 LEFTA LEFTY2 LEFTYA LGALS3BP LHFPL2 LY6G6D LY6G6F M2BP MAGED2 MANF MIC27 MIC3 MIG2B MLA1 MMRN MMRN1 MOATB MRP4 NG32 NHLRC2 NQO3A2 OLA1 ON ORM1 ORM2 P47 PAI1 PCDH7 PCYOX1L PDGF2 PDGFB PECAM1 PF4 PFD PFN1 PHACTR2 PI PI4 PK120 PLANH1 PLEK PLG PLI POTEKP PP4 PPBP PPIA PRG PRG1 PROS PROS1 PSAP QSCN6 QSOX1 RAB27B RARRES2 SAP1 SCCPDH SCG3 SCYB4 SCYB7 SELENOP SELP SEPP1 SERPINA1 SERPINA3 SERPINA4 SERPINE1 SERPINF2 SERPING1 SIS SOD1 SPARC SPP2 SPP24 SRGN STXBP2 SYTL4 TAGLN2 TB4X TEX264 TF TGB1 TGFB TGFB1 TGFB2 TGFB3 TGFB4 THBGB1 THBS1 THYB4 TIG2 TIMP TIMP1 TIMP3 TLN TLN1 TMSB4 TMSB4X TMX3 TNA TOR4A TSP TSP1 TSPAN29 TSPAN30 TTN TUBA1 TUBA4A TXNDC10 UNC18B URP2 VCL VEGF VEGFA VEGFB VEGFC VEGFD VRF VTI1 VTI1B VTI1L VTI1L1 VTI2 VWF WDR1 ZSIG11
Golgi Associated Vesicle Biogenesis	ADP-ribosylation factor 1 AP-1 complex subunit beta-1 AP-1 complex subunit gamma-1 AP-1 complex subunit mu-1 AP-1 complex subunit mu-2 AP-1 complex subunit sigma-1A AP-1 complex subunit sigma-2 AP-1 complex subunit sigma-3 AP-3 complex subunit beta-1 AP-3 complex subunit sigma-1 AP-4 complex subunit beta-1 AP-4 complex subunit epsilon-1 Adaptin ear-binding coat-associated protein 1 Alpha-soluble NSF attachment protein Auxilin Beta-arrestin-1 Biogenesis of lysosome-related organelles complex 1 subunit 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 Biogenesis of lysosome-related organelles complex 1 subunit 4 Biogenesis of lysosome-related organelles complex 1 subunit 6 Carboxypeptidase D Cation-independent mannose-6-phosphate receptor Clathrin interactor 1 Cyclin-G-associated kinase Dynamin-2 Dysbindin Endophilin-A1 Ferritin heavy chain Ferritin light chain Golgi resident protein GCP60 Golgin subfamily B member 1 Heat shock cognate 71 kDa protein Huntingtin-interacting protein 1-related protein Inositol polyphosphate 5-phosphatase OCRL Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha Phosphatidylinositol-binding clathrin assembly protein Protein YIPF6 Pumilio homolog 1 Ras-related protein Rab-5C SH3 domain-containing protein 19 SNARE-associated protein Snapin Sortilin Sorting nexin-2 Sorting nexin-5 Sorting nexin-9 TBC1 domain family member 8B Thioredoxin domain-containing protein 5 Trans-Golgi network integral membrane protein 2 Transferrin receptor protein 1 Tumor protein D52 Tumor protein D53 Vesicle-associated membrane protein 2 Vesicle-associated membrane protein 7 Vesicle-associated membrane protein 8	O00203 O00443 O14976 O43493 O43747 O60749 O75061 O75146 O75976 O95295 P02786 P02792 P02794 P11142 P11717 P49407 P50570 P51148 P51809 P54920 P55327 P56377 P61966 P63027 P78537 P84077 Q01968 Q0IIM8 Q10567 Q13492 Q14671 Q14677 Q14789 Q16890 Q5HYK7 Q6QNY0 Q8NBS9 Q8NC96 Q92572 Q96EC8 Q96EV8 Q96PC3 Q99523 Q99962 Q9BV40 Q9BXS5 Q9H3P7 Q9NUP1 Q9UL45 Q9UPM8 Q9Y5X1 Q9Y5X3 Q9Y6B7 Q9Y6Q5	ACBD3 ADTB1 ADTB3A ADTG AP19 AP1B1 AP1G1 AP1M1 AP1M2 AP1S1 AP1S2 AP1S3 AP3B1 AP3S1 AP4B1 AP4E1 ARF1 ARR1 ARRB1 BAM22 BLOC1S1 BLOC1S3 BLOC1S4 BLOC1S6 BLOC1S7 BLOC1S8 BLOS1 BLOS3 CALM CLAPB2 CLAPG1 CLAPS1 CLAPS3 CLINT1 CLTNM CNO CNSA2 CPD DNAJC26 DNAJC6 DNM2 DTNBP1 DYN2 ENTH EPN4 EPNR FTH FTH1 FTHL6 FTL GAK GCN5L1 GCP60 GOCAP1 GOLGB1 GOLPH1 HIP12 HIP1R HSC70 HSP73 HSPA10 HSPA8 IGF2R KIAA0099 KIAA0171 KIAA0473 KIAA0655 MPRI NAPA NECAP1 OCRL OCRL1 PA PICALM PIK3C2A PLDN PUM1 PUMH1 RAB5C RABL RT14 SH3D19 SH3D2A SH3GL2 SH3PX1 SH3PXD3A SNAP25BP SNAPA SNAPAP SNAPIN SNX2 SNX5 SNX9 SORT1 SYB2 SYBL1 TBC1D8B TFRC TGN46 TGN51 TGOLN2 TLP46 TPD52 TPD52L1 TXNDC5 VAMP2 VAMP7 VAMP8 YIPF6
Signaling by BRAF and RAF1 fusions	14-3-3 protein beta/alpha A-kinase anchor protein 9 AP-3 complex subunit beta-1 Acylglycerol kinase, mitochondrial Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Angiogenic factor with G patch and FHA domains 1 Bcl-2-like protein 11 Beta-arrestin-1 Beta-arrestin-2 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Connector enhancer of kinase suppressor of ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Epithelial splicing regulatory protein 1 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase NRas H(+)/Cl(-) exchange transporter 6 Integrin alpha-IIb Integrin beta-3 KH domain-containing RNA-binding protein QKI Kinase suppressor of Ras 1 Kinase suppressor of Ras 2 Lysine-specific demethylase 7A MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Myosin phosphatase Rho-interacting protein Phosphatidylethanolamine-binding protein 1 Prelamin-A/C Protein FAM114A2 Protein FAM131B Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase RNA-binding protein FXR1 Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A Ras-related protein Rap-1b Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Staphylococcal nuclease domain-containing protein 1 Talin-1 Terminal nucleotidyltransferase 4A Trafficking kinesin-binding protein 1 Transcription intermediary factor 1-alpha Type-1 angiotensin II receptor-associated protein Tyrosine-protein kinase CSK Tyrosine-protein kinase JAK2 UPF0606 protein KIAA1549 Ubiquitin-like modifier-activating enzyme ATG7 Vinculin Zinc finger CCCH-type antiviral protein 1 von Willebrand factor	O00203 O15164 O43252 O43521 O60674 O95352 P01111 P01112 P02545 P02671 P02675 P02679 P02751 P04049 P04275 P05106 P08514 P0DP23 P10398 P12931 P15056 P18206 P27361 P27448 P28482 P30086 P31946 P32121 P36507 P41240 P46940 P49407 P51114 P51797 P61224 P62834 Q02750 Q13554 Q13555 Q13557 Q53H12 Q5XG87 Q6NXG1 Q6RW13 Q6VAB6 Q6WCQ1 Q6ZMT4 Q7KZF4 Q7Z2W4 Q7Z5R6 Q86XD5 Q8IVT5 Q8N302 Q8WXI2 Q969H4 Q96PU8 Q99996 Q9HCM3 Q9NRY5 Q9UPV9 Q9UQM7 Q9Y490	ADTB3A AGGF1 AGK AGTRAP AKAP350 AKAP450 AKAP9 AP3B1 APBB1IP APG7L ARAF ARAF1 ARB2 ARR1 ARR2 ARRB1 ARRB2 ATG7 ATPSK1 ATRAP BCL2L11 BIM BRAF BRAF1 C5orf3 CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CLCN6 CNK1 CNK2 CNKSR1 CNKSR2 CSK CTAK1 EMK2 ERK1 ERK2 ESRP1 F8VWF FAM114A2 FAM131B FGA FGB FGG FN FN1 FXR1 GP2B GP3A GPATC7 GPATCH7 HKQ HRAS HRAS1 IQGAP1 ITGA2B ITGAB ITGB3 JAK2 JHDM1D KDM7 KDM7A KIAA0046 KIAA0051 KIAA0773 KIAA0803 KIAA0864 KIAA0902 KIAA0968 KIAA1027 KIAA1042 KIAA1549 KIAA1718 KREV1 KSR KSR1 KSR2 LMN1 LMNA MAP2K1 MAP2K2 MAPK1 MAPK3 MARK3 MEK1 MEK2 MKK2 MPRIP MRIP MULK NRAS OIP106 PAPD7 PAPSS PAPSS1 PBP PEBP PEBP1 PKS PKS2 POLS PREL1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 QKI RAF RAF1 RAFB1 RAP1A RAP1B RARP1 RBM35A RHOIP3 RIAM RNF82 SND1 SRC SRC1 TDRD11 TENT4A TIF1 TIF1A TLN TLN1 TRAK1 TRF4 TRIM24 VCL VG5Q VWF YWHAB ZC3HAV1 ZC3HDC2
Ligand-dependent caspase activation	Caspase-8 FAS-associated death domain protein FLICE inhibitory protein Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Receptor-interacting serine/threonine-protein kinase 1 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 TNF receptor-associated factor 2 Toll-like receptor 4 Tumor necrosis factor ligand superfamily member 10 Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor type 1-associated DEATH domain protein Viral CASP8 and FADD-like apoptosis regulator	O00206 O00220 O14763 P08571 P25445 P48023 P50591 Q12933 Q13158 Q13546 Q14790 Q15628 Q76RF1 Q86XR7 Q8IUC6 Q98325 Q9Y6Y9	APO2 APO2L APT1 APT1LG1 CASP8 CD14 CD95L DR4 DR5 ESOP1 FADD FAS FAS1 FASL FASLG KILLER LY96 MC159L MCH5 MD2 MORT1 ORF71 PRVTIRB RIP RIP1 RIPK1 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TNFRSF10A TNFRSF10B TNFRSF6 TNFSF10 TNFSF6 TRADD TRAF2 TRAIL TRAILR1 TRAILR2 TRAM TRAP3 TRICK2 TRIF ZTNFR9
Heme signaling	3'-5' exoribonuclease HELZ2 Apolipoprotein A-I Apolipoprotein B-100 Basic helix-loop-helix ARNT-like protein 1 C-type lectin domain family 1 member B CREB-binding protein CREB-regulated transcription coactivator 1 CREB-regulated transcription coactivator 2 CREB-regulated transcription coactivator 3 Chromodomain-helicase-DNA-binding protein 9 Circadian locomoter output cycles protein kaput Cyclic AMP-dependent transcription factor ATF-2 Exportin-1 F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Heme oxygenase 1 Hemoglobin subunit alpha Hemoglobin subunit beta Histone acetyltransferase p300 Histone deacetylase 3 Histone-arginine methyltransferase CARM1 Lymphocyte antigen 96 Mediator of RNA polymerase II transcription subunit 1 Membrane-associated progesterone receptor component 2 Myocyte-specific enhancer factor 2C Myocyte-specific enhancer factor 2D NAD-dependent protein deacetylase sirtuin-1 Neuronal PAS domain-containing protein 2 Nuclear factor erythroid 2-related factor 2 Nuclear receptor ROR-alpha Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Nuclear receptor coactivator 6 Nuclear receptor corepressor 1 Nuclear receptor subfamily 1 group D member 1 Nuclear receptor-interacting protein 1 Peroxisome proliferator-activated receptor alpha Peroxisome proliferator-activated receptor gamma coactivator 1-alpha Proton-coupled folate transporter Retinoic acid receptor RXR-alpha Retinoic acid-induced protein 1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 Toll-like receptor 4 Transcription factor MafK Transcription regulator protein BACH1 Trimethylguanosine synthase	O00206 O00327 O14867 O14980 O15173 O15379 O15516 O60675 O60907 O75376 P02647 P04114 P09601 P15336 P19793 P20393 P35398 P48552 P68871 P69905 Q06413 Q07869 Q09472 Q14686 Q14814 Q15596 Q15648 Q15788 Q16236 Q3L8U1 Q53ET0 Q6STE5 Q6UUV7 Q6UUV9 Q7Z5J4 Q86X55 Q92793 Q96EB6 Q96NT5 Q96RS0 Q99743 Q9BYK8 Q9BZK7 Q9P126 Q9UBK2 Q9Y6Y9	AIB3 APOA1 APOB ARC205 ARNTL ATF2 BACH1 BAF60C BHLHE5 BHLHE74 BHLHE75 BHLHE8 BHLHE9 BMAL1 CARM1 CBP CHD9 CLEC1B CLEC2 CLOCK CREB2 CREBBP CREBP1 CRM1 CRSP1 CRSP200 CRTC1 CRTC2 CRTC3 DG6 DRIP205 DRIP230 EAR1 EP300 ESOP1 G21 HBA1 HBA2 HBB HCA137 HCP1 HDAC3 HELZ2 HMOX1 HO HO1 HREV IRA1 KIAA0181 KIAA0308 KIAA0334 KIAA0616 KIAA1047 KIAA1769 KIAA1820 KISH2 LEM6 LY96 MAFK MD2 MECT1 MED1 MEF2C MEF2D MOP3 MOP4 NCOA1 NCOA2 NCOA6 NCOA6IP NCOR1 NFE2L2 NPAS2 NR1C1 NR1D1 NR1F1 NR2B1 NRF2 NRIP1 P300 PASD3 PASD4 PBP PCFT PGC1 PGC1A PGRMC2 PIMT PMBP PPAR PPARA PPARBP PPARGBP PPARGC1 PPARGC1A PRIC285 PRIC320 PRMT4 RAI1 RAP250 RB18A RORA RXRA RZRA SIR2L1 SIRT1 SLC46A1 SMARCD3 SRC1 SRC2 TBL1 TBL1X TBL1XR1 TBLR1 TGS1 THRAL TIF2 TLR4 TORC1 TORC2 TORC3 TRAP220 TRBP TRIP2 WAMTP1 XPO1
Respiratory syncytial virus (RSV) attachment and entry	Agrin Basement membrane-specific heparan sulfate proteoglycan core protein CX3C chemokine receptor 1 Epidermal growth factor receptor Furin Fusion glycoprotein F0 Glypican-1 Glypican-2 Glypican-3 Glypican-4 Glypican-5 Glypican-6 Insulin-like growth factor 1 receptor Lymphocyte antigen 96 Matrix protein Monocyte differentiation antigen CD14 Nucleolin Nucleoprotein Phosphoprotein Protein M2-1 RNA-directed RNA polymerase L Ras-related protein Rab-5A Ras-related protein Rab-5B Ras-related protein Rab-5C Syndecan-1 Syndecan-2 Syndecan-3 Syndecan-4 Toll-like receptor 4	O00206 O00468 O75056 O75487 P00533 P03418 P03420 P03421 P04545 P08069 P08571 P09958 P0DOE7 P18827 P19338 P20339 P28887 P31431 P34741 P35052 P49238 P51148 P51654 P61020 P78333 P98160 Q8N158 Q9Y625 Q9Y6Y9	AGRIN AGRN CD14 CMKBRL1 CX3CR1 EGFR ERBB ERBB1 ESOP1 F FUR FURIN GPC1 GPC2 GPC3 GPC4 GPC5 GPC6 GPR13 HER1 HSPG1 HSPG2 IGF1R KIAA0468 L LY96 M M2-1 MD2 N NCL OCI5 P PACE PCSK3 RAB5 RAB5A RAB5B RAB5C RABL SDC SDC1 SDC2 SDC3 SDC4 TLR4
IKK complex recruitment mediated by RIP1	Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Lymphocyte antigen 96 Monocyte differentiation antigen CD14 NF-kappa-B essential modulator Polyubiquitin-B Polyubiquitin-C Receptor-interacting serine/threonine-protein kinase 1 Receptor-interacting serine/threonine-protein kinase 3 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 TNF receptor-associated factor 6 Toll-like receptor 4 Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00206 O14920 O15111 P08571 P0CG47 P0CG48 P51668 P61077 P61088 P62837 P62979 P62987 Q13404 Q13489 Q13490 Q13546 Q86XR7 Q8IUC6 Q9Y4K3 Q9Y572 Q9Y6K9 Q9Y6Y9	API1 API2 BIRC2 BIRC3 BLU CD14 CHUK CROC1 ESOP1 FIP3 IKBKB IKBKG IKKA IKKB LY96 MD2 MIHB MIHC NEMO PRVTIRB PUBC1 RIP RIP1 RIP3 RIPK1 RIPK3 RNF48 RNF49 RNF85 RPS27A SFT TCF16 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAF6 TRAM TRIF UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBC5C UBCEP1 UBCEP2 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBE2D1 UBE2D2 UBE2D3 UBE2N UBE2V UBE2V1 UEV1
MyD88:MAL(TIRAP) cascade initiated on plasma membrane	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain High mobility group protein B1 Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase 3 Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-associated kinase-like 2 Lymphocyte antigen 96 Major outer membrane protein P.IB Mitogen-activated protein kinase kinase kinase 1 Monocyte differentiation antigen CD14 Myeloid differentiation primary response protein MyD88 Peptidyl-prolyl cis-trans isomerase Mip Platelet glycoprotein 4 Protein S100-A1 Protein S100-A8 Protein S100-A9 Single Ig IL-1-related receptor Suppressor of cytokine signaling 1 TNF receptor-associated factor 6 Toll-like receptor 1 Toll-like receptor 2 Toll-like receptor 4 Toll-like receptor 6 Toll/interleukin-1 receptor domain-containing adapter protein Tyrosine-protein kinase BTK	O00206 O15524 O43187 O60603 P02671 P02675 P02679 P05109 P06702 P08571 P09429 P16671 P23297 P26623 P30690 P51617 P58753 Q06187 Q13233 Q15399 Q6IA17 Q99836 Q9BQ95 Q9NWZ3 Q9Y2C9 Q9Y4K3 Q9Y616 Q9Y6Y9	AGMX1 ATK BPK BTK CAGA CAGB CD14 CD36 CFAG ECSIT ESOP1 FGA FGB FGG GP3B GP4 HMG1 HMGB1 IRAK IRAK1 IRAK2 IRAK3 IRAK4 KIAA0012 LY96 MAL MAP3K1 MAPKKK1 MD2 MEKK MEKK1 MRP14 MRP8 MYD88 RNF85 S100A S100A1 S100A8 S100A9 SIGIRR SOCS1 SSI1 TIL4 TIP3 TIRAP TLR1 TLR2 TLR4 TLR6 TRAF6 mip porB
TRAF6-mediated induction of TAK1 complex within TLR4 complex	Interleukin-1 receptor-associated kinase-like 2 Lymphocyte antigen 96 Mitogen-activated protein kinase kinase kinase 7 Monocyte differentiation antigen CD14 Polyubiquitin-B Polyubiquitin-C TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 TNF receptor-associated factor 6 Toll-like receptor 4 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00206 O43187 O43318 P08571 P0CG47 P0CG48 P62979 P62987 Q15750 Q86XR7 Q8IUC6 Q8N5C8 Q9NYJ8 Q9Y4K3 Q9Y6Y9	CD14 ESOP1 IRAK2 KIAA0733 LY96 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MD2 PRVTIRB RNF85 RPS27A TAB1 TAB2 TAB3 TAK1 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAF6 TRAM TRIF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	Interleukin-1 receptor-associated kinase-like 2 Lymphocyte antigen 96 Mitogen-activated protein kinase kinase kinase 7 Monocyte differentiation antigen CD14 Polyubiquitin-B Polyubiquitin-C TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 TNF receptor-associated factor 6 Toll-like receptor 4 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00206 O43187 O43318 P08571 P0CG47 P0CG48 P62979 P62987 Q15750 Q86XR7 Q8IUC6 Q8N5C8 Q9NYJ8 Q9Y4K3 Q9Y6Y9	CD14 ESOP1 IRAK2 KIAA0733 LY96 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MD2 PRVTIRB RNF85 RPS27A TAB1 TAB2 TAB3 TAK1 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAF6 TRAM TRIF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Regulation of TLR by endogenous ligand	Apolipoprotein B-100 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Gasdermin-D Gasdermin-E High mobility group protein B1 Lipopolysaccharide-binding protein Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Platelet glycoprotein 4 Protein S100-A1 Protein S100-A8 Protein S100-A9 Toll-like receptor 1 Toll-like receptor 2 Toll-like receptor 4 Toll-like receptor 6 Toll-like receptor 7	O00206 O60443 O60603 P02671 P02675 P02679 P04114 P05109 P06702 P08571 P09429 P16671 P18428 P23297 P57764 Q15399 Q9NYK1 Q9Y2C9 Q9Y6Y9	APOB CAGA CAGB CD14 CD36 CFAG DFNA5 DFNA5L ESOP1 FGA FGB FGG GP3B GP4 GSDMD GSDMDC1 GSDME HMG1 HMGB1 ICERE1 KIAA0012 LBP LY96 MD2 MRP14 MRP8 S100A S100A1 S100A8 S100A9 TIL4 TLR1 TLR2 TLR4 TLR6 TLR7
IRAK4 deficiency (TLR2/4)	Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain High mobility group protein B1 Interleukin-1 receptor-associated kinase 4 Lymphocyte antigen 96 Major outer membrane protein P.IB Monocyte differentiation antigen CD14 Myeloid differentiation primary response protein MyD88 Peptidyl-prolyl cis-trans isomerase Mip Platelet glycoprotein 4 Protein S100-A1 Protein S100-A8 Protein S100-A9 Toll-like receptor 1 Toll-like receptor 2 Toll-like receptor 4 Toll-like receptor 6 Toll/interleukin-1 receptor domain-containing adapter protein Tyrosine-protein kinase BTK	O00206 O60603 P02671 P02675 P02679 P05109 P06702 P08571 P09429 P16671 P23297 P26623 P30690 P58753 Q06187 Q15399 Q99836 Q9NWZ3 Q9Y2C9 Q9Y6Y9	AGMX1 ATK BPK BTK CAGA CAGB CD14 CD36 CFAG ESOP1 FGA FGB FGG GP3B GP4 HMG1 HMGB1 IRAK4 KIAA0012 LY96 MAL MD2 MRP14 MRP8 MYD88 S100A S100A1 S100A8 S100A9 TIL4 TIRAP TLR1 TLR2 TLR4 TLR6 mip porB
MyD88 deficiency (TLR2/4)	Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain High mobility group protein B1 Lymphocyte antigen 96 Major outer membrane protein P.IB Monocyte differentiation antigen CD14 Myeloid differentiation primary response protein MyD88 Peptidyl-prolyl cis-trans isomerase Mip Platelet glycoprotein 4 Protein S100-A1 Protein S100-A8 Protein S100-A9 Toll-like receptor 1 Toll-like receptor 2 Toll-like receptor 4 Toll-like receptor 6 Toll/interleukin-1 receptor domain-containing adapter protein Tyrosine-protein kinase BTK	O00206 O60603 P02671 P02675 P02679 P05109 P06702 P08571 P09429 P16671 P23297 P26623 P30690 P58753 Q06187 Q15399 Q99836 Q9Y2C9 Q9Y6Y9	AGMX1 ATK BPK BTK CAGA CAGB CD14 CD36 CFAG ESOP1 FGA FGB FGG GP3B GP4 HMG1 HMGB1 KIAA0012 LY96 MAL MD2 MRP14 MRP8 MYD88 S100A S100A1 S100A8 S100A9 TIL4 TIRAP TLR1 TLR2 TLR4 TLR6 mip porB
Toll Like Receptor 4 (TLR4) Cascade	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 Bactericidal permeability-increasing protein CD180 antigen Dynamin-1 Dynamin-2 Dynamin-3 Integrin alpha-M Integrin beta-2 Lipopolysaccharide-binding protein Lymphocyte antigen 86 Lymphocyte antigen 96 Monocyte differentiation antigen CD14 TIR domain-containing adapter molecule 2 Toll-like receptor 4 Tyrosine-protein phosphatase non-receptor type 4	O00206 O95711 P05107 P08571 P11215 P16885 P17213 P18428 P29074 P50570 Q05193 Q86XR7 Q99467 Q9UQ16 Q9Y6Y9	BPI CD11B CD14 CD18 CD180 CR3A DNM DNM1 DNM2 DNM3 DYN2 ESOP1 ITGAM ITGB2 KIAA0820 LBP LY64 LY86 LY96 MD1 MD2 MFI7 PLCG2 PTPN4 RP105 TICAM2 TIRAP3 TIRP TLR4 TRAM
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE)	Inhibitor of nuclear factor kappa-B kinase subunit epsilon Interferon regulatory factor 3 Interferon regulatory factor 7 Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Optineurin Polyubiquitin-B Polyubiquitin-C Serine/threonine-protein kinase TBK1 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 TNF receptor-associated factor 3 TRAF family member-associated NF-kappa-B activator Toll-like receptor 4 Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00206 P08571 P0CG47 P0CG48 P62979 P62987 Q06124 Q13114 Q14164 Q14653 Q86XR7 Q8IUC6 Q92844 Q92985 Q96CV9 Q9UHD2 Q9Y6Y9	CAP-1 CD14 CRAF1 ESOP1 FIP2 GLC1E HIP7 HYPL IKBKE IKKE IKKI IRF3 IRF7 ITRAF KIAA0151 LY96 MD2 NAK NRP OPTN PRVTIRB PTP2C PTPN11 RPS27A SHPTP2 TANK TBK1 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAF2 TRAF3 TRAFAMN TRAM TRIF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7	Inhibitor of nuclear factor kappa-B kinase subunit epsilon Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Optineurin Polyubiquitin-B Polyubiquitin-C Serine/threonine-protein kinase TBK1 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 TNF receptor-associated factor 3 TRAF family member-associated NF-kappa-B activator Toll-like receptor 4 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00206 P08571 P0CG47 P0CG48 P62979 P62987 Q13114 Q14164 Q86XR7 Q8IUC6 Q92844 Q96CV9 Q9UHD2 Q9Y6Y9	CAP-1 CD14 CRAF1 ESOP1 FIP2 GLC1E HIP7 HYPL IKBKE IKKE IKKI ITRAF KIAA0151 LY96 MD2 NAK NRP OPTN PRVTIRB RPS27A TANK TBK1 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAF2 TRAF3 TRAFAMN TRAM TRIF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
TRIF-mediated programmed cell death	Caspase-8 FAS-associated death domain protein Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Receptor-interacting serine/threonine-protein kinase 1 Receptor-interacting serine/threonine-protein kinase 3 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 Toll-like receptor 4	O00206 P08571 Q13158 Q13546 Q14790 Q86XR7 Q8IUC6 Q9Y572 Q9Y6Y9	CASP8 CD14 ESOP1 FADD LY96 MCH5 MD2 MORT1 PRVTIRB RIP RIP1 RIP3 RIPK1 RIPK3 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAM TRIF
MyD88-independent TLR4 cascade	Lymphocyte antigen 96 Monocyte differentiation antigen CD14 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 Toll-like receptor 4	O00206 P08571 Q86XR7 Q8IUC6 Q9Y6Y9	CD14 ESOP1 LY96 MD2 PRVTIRB TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAM TRIF
Respiratory electron transport	Acyl carrier protein, mitochondrial Coenzyme Q-binding protein COQ10 homolog A, mitochondrial Coenzyme Q-binding protein COQ10 homolog B, mitochondrial Cytochrome b-c1 complex subunit 1, mitochondrial Cytochrome b-c1 complex subunit 10 Cytochrome b-c1 complex subunit 2, mitochondrial Cytochrome b-c1 complex subunit 6, mitochondrial Cytochrome b-c1 complex subunit 7 Cytochrome b-c1 complex subunit 8 Cytochrome b-c1 complex subunit 9 Cytochrome b-c1 complex subunit Rieske, mitochondrial Cytochrome b Cytochrome c oxidase assembly factor 1 homolog Cytochrome c oxidase assembly protein COX11, mitochondrial Cytochrome c oxidase assembly protein COX14 Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial Cytochrome c oxidase assembly protein COX18, mitochondrial Cytochrome c oxidase assembly protein COX19 Cytochrome c oxidase assembly protein COX20, mitochondrial Cytochrome c oxidase subunit 1 Cytochrome c oxidase subunit 2 Cytochrome c oxidase subunit 3 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial Cytochrome c oxidase subunit 5A, mitochondrial Cytochrome c oxidase subunit 5B, mitochondrial Cytochrome c oxidase subunit 6A1, mitochondrial Cytochrome c oxidase subunit 6B1 Cytochrome c oxidase subunit 6C Cytochrome c oxidase subunit 7A-related protein, mitochondrial Cytochrome c oxidase subunit 7B, mitochondrial Cytochrome c oxidase subunit 7C, mitochondrial Cytochrome c oxidase subunit 8A, mitochondrial Cytochrome c oxidase subunit NDUFA4 Cytochrome c1, heme protein, mitochondrial Cytochrome c Electron transfer flavoprotein subunit alpha, mitochondrial Electron transfer flavoprotein subunit beta Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial Heat shock protein 75 kDa, mitochondrial Leucine-rich PPR motif-containing protein, mitochondrial NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NADH dehydrogenase [ubiquinone] 1 subunit C2 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NADH-ubiquinone oxidoreductase chain 1 NADH-ubiquinone oxidoreductase chain 2 NADH-ubiquinone oxidoreductase chain 3 NADH-ubiquinone oxidoreductase chain 4 NADH-ubiquinone oxidoreductase chain 5 NADH-ubiquinone oxidoreductase chain 6 Protein SCO1 homolog, mitochondrial Protein SCO2 homolog, mitochondrial Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Succinate dehydrogenase cytochrome b560 subunit, mitochondrial Surfeit locus protein 1 Translational activator of cytochrome c oxidase 1 Transmembrane protein 186	O00217 O00483 O14521 O14548 O14561 O14949 O14957 O15239 O43181 O43674 O43676 O43677 O43678 O43819 O43920 O75251 O75306 O75380 O75438 O75489 O75880 O95139 O95167 O95168 O95169 O95178 O95182 O95298 O95299 O96000 P00156 P00395 P00403 P00414 P03886 P03891 P03897 P03905 P03915 P03923 P07919 P08574 P09669 P10176 P10606 P12074 P13073 P13804 P14854 P14927 P15954 P17568 P19404 P20674 P21912 P22695 P24311 P28331 P31040 P31930 P38117 P42704 P47985 P49821 P51970 P56181 P56556 P99999 Q12931 Q15526 Q16134 Q16718 Q16795 Q49B96 Q5RI15 Q86Y39 Q8N8Q8 Q96B77 Q96I36 Q96MF6 Q99643 Q9BSH4 Q9GZY4 Q9H8M1 Q9NX14 Q9P0J0 Q9P0S2 Q9UDW1 Q9UI09 Q9Y6M9 Q9Y6N1	C12orf62 C14orf112 C16orf51 C7orf44 CCDC44 COA1 COB COI COII COIII COQ10A COQ10B COX11 COX14 COX16 COX18 COX19 COX2 COX20 COX4 COX4I1 COX5A COX5B COX6A1 COX6AL COX6B COX6B1 COX6C COX7A2L COX7AR COX7B COX7C COX7RP COX8 COX8A COX8L COXI COXII COXIII CYB560 CYC CYC1 CYCS CYTB DAP13 ETFA ETFB ETFDH FAM36A GRIM19 HSP75 HSPC5 LRP130 LRPPRC LYRM3 LYRM6 MITRAC15 MT-CO1 MT-CO2 MT-CO3 MT-CYB MT-ND1 MT-ND2 MT-ND3 MT-ND4 MT-ND5 MT-ND6 MTCO1 MTCO2 MTCO3 MTCYB MTND1 MTND2 MTND3 MTND4 MTND5 MTND6 NADH1 NADH2 NADH3 NADH4 NADH5 NADH6 NADHB14 ND1 ND2 ND3 ND4 ND5 ND6 NDUFA1 NDUFA10 NDUFA11 NDUFA12 NDUFA13 NDUFA2 NDUFA3 NDUFA4 NDUFA5 NDUFA6 NDUFA7 NDUFA8 NDUFA9 NDUFAB1 NDUFB1 NDUFB10 NDUFB11 NDUFB2 NDUFB3 NDUFB4 NDUFB5 NDUFB6 NDUFB7 NDUFB8 NDUFB9 NDUFC1 NDUFC2 NDUFS1 NDUFS2 NDUFS2L NDUFS3 NDUFS4 NDUFS5 NDUFS6 NDUFS7 NDUFS8 NDUFV1 NDUFV2 NDUFV3 OXA1L2 SCO1 SCO2 SCOD1 SDH SDH1 SDH2 SDH3 SDH4 SDHA SDHB SDHC SDHD SDHF SURF-1 SURF1 TACO1 TMEM186 TRAP1 UCRC UQBP UQCR UQCR10 UQCR11 UQCRB UQCRC1 UQCRC2 UQCRFS1 UQCRH UQCRQ UQOR1 UQOR22
Complex I biogenesis	Acyl carrier protein, mitochondrial Arginine-hydroxylase NDUFAF5, mitochondrial Complex I assembly factor ACAD9, mitochondrial Complex I assembly factor TIMMDC1, mitochondrial Complex I assembly factor TMEM126B, mitochondrial Complex I intermediate-associated protein 30, mitochondrial Cytochrome c oxidase assembly factor 1 homolog Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Iron-sulfur cluster transfer protein NUBPL NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NADH dehydrogenase [ubiquinone] 1 subunit C2 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NADH-ubiquinone oxidoreductase chain 1 NADH-ubiquinone oxidoreductase chain 2 NADH-ubiquinone oxidoreductase chain 3 NADH-ubiquinone oxidoreductase chain 4 NADH-ubiquinone oxidoreductase chain 5 NADH-ubiquinone oxidoreductase chain 6 Protein arginine methyltransferase NDUFAF7, mitochondrial Transmembrane protein 186	O00217 O14561 O15239 O43181 O43674 O43676 O43677 O43678 O43920 O75251 O75306 O75380 O75438 O75489 O95139 O95167 O95168 O95169 O95178 O95182 O95298 O95299 O96000 P03886 P03891 P03897 P03905 P03915 P03923 P17568 P19404 P28331 P49821 P51970 P56181 P56556 Q16718 Q16795 Q330K2 Q5TEU4 Q7L592 Q86Y39 Q8IUX1 Q8N183 Q8TB37 Q96B77 Q9BQ95 Q9BU61 Q9GZY4 Q9H845 Q9NPL8 Q9NX14 Q9P032 Q9P0J0 Q9UI09 Q9Y375 Q9Y6M9	ACAD9 C14orf127 C16orf51 C20orf7 C2orf56 C3orf1 C3orf60 C6orf66 C7orf44 C8orf38 CIA30 COA1 DAP13 ECSIT GRIM19 HRPAP20 LYRM3 LYRM6 MITRAC15 MT-ND1 MT-ND2 MT-ND3 MT-ND4 MT-ND5 MT-ND6 MTND1 MTND2 MTND3 MTND4 MTND5 MTND6 NADH1 NADH2 NADH3 NADH4 NADH5 NADH6 NADHB14 ND1 ND2 ND3 ND4 ND5 ND6 NDUFA1 NDUFA10 NDUFA11 NDUFA12 NDUFA12L NDUFA13 NDUFA2 NDUFA3 NDUFA5 NDUFA6 NDUFA7 NDUFA8 NDUFA9 NDUFAB1 NDUFAF1 NDUFAF2 NDUFAF3 NDUFAF4 NDUFAF5 NDUFAF6 NDUFAF7 NDUFB1 NDUFB10 NDUFB11 NDUFB2 NDUFB3 NDUFB4 NDUFB5 NDUFB6 NDUFB7 NDUFB8 NDUFB9 NDUFC1 NDUFC2 NDUFS1 NDUFS2 NDUFS2L NDUFS3 NDUFS4 NDUFS5 NDUFS6 NDUFS7 NDUFS8 NDUFV1 NDUFV2 NDUFV3 NUBPL TIMMDC1 TMEM126B TMEM186 UQOR1 UQOR22
Hyaluronan biosynthesis and export	ATP-binding cassette sub-family C member 5 Cell migration-inducing and hyaluronan-binding protein Hyaluronan synthase 1 Hyaluronan synthase 2 Hyaluronan synthase 3	O00219 O15440 Q8WUJ3 Q92819 Q92839	ABCC5 CEMIP HAS HAS1 HAS2 HAS3 HYBID KIAA1199 MRP5	G35674CY
RIPK1-mediated regulated necrosis	Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 Caspase-8 E3 ubiquitin-protein ligase CHIP E3 ubiquitin-protein ligase XIAP FAS-associated death domain protein Flotillin-1 Flotillin-2 Mixed lineage kinase domain-like protein Non-structural protein 1 Programmed cell death 6-interacting protein Receptor-interacting serine/threonine-protein kinase 1 Receptor-interacting serine/threonine-protein kinase 3 Ribonucleoside-diphosphate reductase large subunit Syntenin-1 TNF receptor-associated factor 2 Tumor necrosis factor ligand superfamily member 10 Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor type 1-associated DEATH domain protein UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit	O00220 O00560 O14763 O15294 O75955 P03496 P08543 P25445 P48023 P50591 P98170 Q12933 Q13158 Q13489 Q13490 Q13546 Q14254 Q14790 Q15628 Q8NB16 Q8WUM4 Q9UNE7 Q9Y572	AIP1 ALIX API1 API2 API3 APO2 APO2L APT1 APT1LG1 BIRC2 BIRC3 BIRC4 CASP8 CD95L CHIP DR4 DR5 ESA1 FADD FAS FAS1 FASL FASLG FLOT1 FLOT2 IAP3 ICP6 KIAA1375 KILLER M17S1 MCH5 MDA9 MIHB MIHC MLKL MORT1 NS OGT PDCD6IP RIP RIP1 RIP3 RIPK1 RIPK3 RIR1 RNF48 RNF49 SDCBP STUB1 SYCL TNFRSF10A TNFRSF10B TNFRSF6 TNFSF10 TNFSF6 TRADD TRAF2 TRAIL TRAILR1 TRAILR2 TRAP3 TRICK2 XIAP ZTNFR9
TP53 Regulates Transcription of Death Receptors and Ligands	Apoptosis-stimulating of p53 protein 1 Apoptosis-stimulating of p53 protein 2 Cellular tumor antigen p53 Insulin-like growth factor-binding protein 3 receptor Insulin-like growth factor-binding protein 3 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 10C Tumor necrosis factor receptor superfamily member 10D Tumor necrosis factor receptor superfamily member 6 Tumor protein 63 Tumor protein p73	O00220 O14763 O14798 O15350 P04637 P17936 P25445 Q13625 Q86XT9 Q96KQ4 Q9H3D4 Q9UBN6	APO2 APT1 ASPP1 ASPP2 BBP DCR1 DCR2 DR4 DR5 FAS FAS1 IBP3 IGFBP3 KET KIAA0771 KILLER LIT P53 P63 P73 P73H P73L PPP1R13B TMEM219 TNFRSF10A TNFRSF10B TNFRSF10C TNFRSF10D TNFRSF6 TP53 TP53BP2 TP63 TP73 TP73L TRAILR1 TRAILR2 TRAILR3 TRAILR4 TRICK2 TRID TRUNDD ZTNFR9
TRAIL signaling	CASP8 and FADD-like apoptosis regulator Caspase-10 Caspase-8 FAS-associated death domain protein Tumor necrosis factor ligand superfamily member 10 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 10D	O00220 O14763 O15519 P50591 Q13158 Q14790 Q92851 Q9UBN6	APO2 APO2L CASH CASP10 CASP8 CASP8AP1 CFLAR CLARP DCR2 DR4 DR5 FADD KILLER MCH4 MCH5 MORT1 MRIT TNFRSF10A TNFRSF10B TNFRSF10D TNFSF10 TRAIL TRAILR1 TRAILR2 TRAILR4 TRICK2 TRUNDD ZTNFR9
CASP8 activity is inhibited	Caspase-8 FAS-associated death domain protein Receptor-interacting serine/threonine-protein kinase 1 TNF receptor-associated factor 2 Tumor necrosis factor ligand superfamily member 10 Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor type 1-associated DEATH domain protein	O00220 O14763 P25445 P48023 P50591 Q12933 Q13158 Q13546 Q14790 Q15628	APO2 APO2L APT1 APT1LG1 CASP8 CD95L DR4 DR5 FADD FAS FAS1 FASL FASLG KILLER MCH5 MORT1 RIP RIP1 RIPK1 TNFRSF10A TNFRSF10B TNFRSF6 TNFSF10 TNFSF6 TRADD TRAF2 TRAIL TRAILR1 TRAILR2 TRAP3 TRICK2 ZTNFR9

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