GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **76 - 100** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol
Synthesis of diphthamide-EEF2	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 Diphthamide biosynthesis protein 3 Diphthine methyl ester synthase Diphthine methyltransferase Diphthine--ammonia ligase DnaJ homolog subfamily C member 24 Elongation factor 2	P13639 Q6P3W2 Q7L8W6 Q96FX2 Q9BQC3 Q9BTV6 Q9BZG8 Q9H2P9	ATPBD4 C9orf112 DESR1 DNAJC24 DPH1 DPH2 DPH2L DPH2L1 DPH2L2 DPH3 DPH4 DPH5 DPH6 DPH7 EEF2 EF2 OVCA1 WDR85 ZCSL2 ZCSL3
Reelin signalling pathway	Disabled homolog 1 Reelin SH3 domain-containing kinase-binding protein 1 Tyrosine-protein kinase Fyn Very low-density lipoprotein receptor	O75553 P06241 P78509 P98155 Q96B97	CIN85 DAB1 FYN RELN SH3KBP1 VLDLR
PTK6 Expression	Endothelial PAS domain-containing protein 1 Glucocorticoid receptor Hypoxia-inducible factor 1-alpha Proline-, glutamic acid- and leucine-rich protein 1 Protein-tyrosine kinase 6	P04150 Q13882 Q16665 Q8IZL8 Q99814	BHLHE73 BHLHE78 BRK EPAS1 GRL HIF1A HIF2A HMX3 MNAR MOP1 MOP2 NR3C1 PASD2 PASD8 PELP1 PTK6
Calcitonin-like ligand receptors	Calcitonin gene-related peptide 1 Calcitonin gene-related peptide 2 Calcitonin gene-related peptide type 1 receptor Calcitonin receptor Calcitonin Islet amyloid polypeptide Pro-adrenomedullin Protein ADM2 Receptor activity-modifying protein 1 Receptor activity-modifying protein 2 Receptor activity-modifying protein 3	O60894 O60895 O60896 P01258 P06881 P10092 P10997 P30988 P35318 Q16602 Q7Z4H4	ADM ADM2 AM AM2 CALC1 CALC2 CALCA CALCB CALCR CALCRL CGRPR IAPP RAMP1 RAMP2 RAMP3
Defective translocation of RB1 mutants to the nucleus	Retinoblastoma-associated protein	P06400	RB1
RUNX2 regulates genes involved in cell migration	Collagenase 3 Core-binding factor subunit beta Integrin alpha-5 Integrin beta-like protein 1 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase	O95965 P08648 P31749 P31751 P45452 Q13951 Q9Y243	AKT1 AKT2 AKT3 CBFB FNRA ITGA5 ITGBL1 MMP13 OSCP PKB PKBG RAC TIED
Acrosome Reaction and Sperm:Oocyte Membrane Binding	Acrosin CD9 antigen Izumo sperm-egg fusion protein 1 Izumo sperm-egg fusion protein 2 Izumo sperm-egg fusion protein 3 Izumo sperm-egg fusion protein 4	P10323 P21926 Q1ZYL8 Q5VZ72 Q6UXV1 Q8IYV9	ACR ACRS C19orf36 C19orf41 C9orf134 CD9 IZUMO1 IZUMO2 IZUMO3 IZUMO4 MIC3 SCRL TSPAN29
PDGFR mutants bind TKIs	Platelet-derived growth factor receptor alpha	P16234	PDGFR2 PDGFRA RHEPDGFRA
Activation of Matrix Metalloproteinases	72 kDa type IV collagenase Cathepsin G Cathepsin K Cathepsin L2 Chymase Chymotrypsinogen B2 Chymotrypsinogen B Collagen alpha-1(XVIII) chain Collagenase 3 Furin Interstitial collagenase Kallikrein-2 Matrilysin Matrix metalloproteinase-14 Matrix metalloproteinase-15 Matrix metalloproteinase-16 Matrix metalloproteinase-17 Matrix metalloproteinase-24 Matrix metalloproteinase-25 Matrix metalloproteinase-9 Metalloproteinase inhibitor 1 Metalloproteinase inhibitor 2 Neutrophil collagenase Neutrophil elastase Plasma kallikrein Plasminogen Serine protease 1 Stromelysin-1 Stromelysin-2 Stromelysin-3 Testican-3 Trypsin-2 Tryptase alpha/beta-1	O60911 P00747 P01033 P03952 P03956 P07477 P07478 P08246 P08253 P08254 P08311 P09237 P09238 P09958 P14780 P16035 P17538 P20151 P22894 P23946 P24347 P39060 P43235 P45452 P50281 P51511 P51512 Q15661 Q6GPI1 Q9BQ16 Q9NPA2 Q9ULZ9 Q9Y5R2	C8orf57 CATL2 CLG CLG1 CLG4A CLG4B CLGI CMA1 COL18A1 CTRB CTRB1 CTRB2 CTSG CTSK CTSL2 CTSO CTSO2 CTSU CTSV CYH CYM ELA2 ELANE FUR FURIN KLK2 KLK3 KLKB1 MMP1 MMP10 MMP11 MMP13 MMP14 MMP15 MMP16 MMP17 MMP2 MMP20 MMP24 MMP25 MMP3 MMP7 MMP8 MMP9 MMPL1 MMPX2 MPSL1 MT4MMP MT5MMP MT6MMP PACE PCSK3 PLG PRSS1 PRSS2 PUMP1 SPOCK3 STMY1 STMY2 STMY3 TICN3 TIMP TIMP1 TIMP2 TPS1 TPS2 TPSAB1 TPSB1 TRP1 TRY1 TRY2 TRYP1 TRYP2
FGFR1c ligand binding and activation	Anosmin-1 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 PDZ domain-containing protein GIPC1 Transforming growth factor beta receptor type 3	O14908 P05230 P08620 P09038 P10767 P23352 P31371 Q03167 Q9GZV9 Q9NP95	ADMLX ANOS1 C19orf3 FGF1 FGF2 FGF20 FGF23 FGF4 FGF6 FGF9 FGFA FGFB GIPC GIPC1 HST HST2 HSTF1 HSTF2 HYPF KAL KAL1 KALIG1 KS3 RGS19IP1 TGFBR3
Nuclear events stimulated by ALK signaling in cancer	Bcl-2-related protein A1 CCAAT/enhancer-binding protein beta Cullin-1 DNA (cytosine-5)-methyltransferase 1 E3 ubiquitin-protein ligase RBX1 Forkhead box protein M1 G2/mitotic-specific cyclin-B1 Granzyme B Helicase MOV-10 Histone deacetylase 1 Inducible T-cell costimulator Interferon regulatory factor 4 Interleukin-10 receptor subunit alpha Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Nucleophosmin Perforin-1 Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Retinoblastoma-associated protein S-phase kinase-associated protein 1 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Small ribosomal subunit protein eS6 Transcription factor JunB Trinucleotide repeat-containing gene 6C protein Twist-related protein 1 Tyrosine-protein kinase ZAP-70 Tyrosine-protein phosphatase non-receptor type 6 Zinc finger C3HC-type protein 1	P06400 P06748 P10144 P14222 P14635 P17275 P17676 P26358 P27361 P28482 P29350 P40763 P42229 P43403 P62753 P62877 P63208 Q08050 Q13547 Q13616 Q13651 Q15306 Q15672 Q16548 Q86WB0 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9UKV8 Q9UL18 Q9Y6W8	AGO1 AGO2 AGO3 AGO4 AILIM AIM APRF BCL2A1 BCL2L5 BFL1 BHLHA38 CCNB CCNB1 CEBPB CGL1 CSPB CTLA1 CUL1 CXXC9 DNMT DNMT1 EIF2C1 EIF2C2 EIF2C3 EIF2C4 EMC19 ERK1 ERK2 FKHL16 FOXM1 GRB GRS GZMB HBPA1 HCP HDAC1 HFH11 ICOS IL10R IL10RA IRF4 JUNB KIAA1567 KIAA1582 KIAA1631 MAPK1 MAPK3 MOV10 MPP2 MUM1 NIPA NPM NPM1 OCP2 PFP PRF1 PRKM1 PRKM2 PRKM3 PTP1C PTPN6 RB1 RBX1 RNF75 ROC1 RPD3L1 RPS6 SKP1 SKP1A SRK STAT3 STAT5 STAT5A TCEB1L TCF5 TNRC6C TWIST TWIST1 WIN ZAP70 ZC3HC1
Signaling downstream of RAS mutants	14-3-3 protein beta/alpha Amyloid beta A4 precursor protein-binding family B member 1-interacting protein BRCA1-associated protein Beta-arrestin-1 Beta-arrestin-2 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Connector enhancer of kinase suppressor of ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase KRas GTPase NRas Integrin alpha-IIb Integrin beta-3 Kinase suppressor of Ras 1 Kinase suppressor of Ras 2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase kinase kinase 11 Phosphatidylethanolamine-binding protein 1 Prohibitin 1 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A Ras-related protein Rap-1b Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Talin-1 Tyrosine-protein kinase CSK Tyrosine-protein kinase JAK2 Vinculin von Willebrand factor	O60674 P01111 P01112 P01116 P02671 P02675 P02679 P02751 P04049 P04275 P05106 P08514 P0DP23 P10398 P12931 P15056 P18206 P27361 P27448 P28482 P30086 P31946 P32121 P35232 P36507 P41240 P46940 P49407 P61224 P62834 Q02750 Q13554 Q13555 Q13557 Q16584 Q6VAB6 Q7Z569 Q7Z5R6 Q8IVT5 Q8WXI2 Q969H4 Q9UQM7 Q9Y490	APBB1IP ARAF ARAF1 ARB2 ARR1 ARR2 ARRB1 ARRB2 BRAF BRAF1 BRAP CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CNK1 CNK2 CNKSR1 CNKSR2 CSK CTAK1 EMK2 ERK1 ERK2 F8VWF FGA FGB FGG FN FN1 GP2B GP3A HRAS HRAS1 IQGAP1 ITGA2B ITGAB ITGB3 JAK2 KIAA0051 KIAA0902 KIAA0968 KIAA1027 KRAS KRAS2 KREV1 KSR KSR1 KSR2 MAP2K1 MAP2K2 MAP3K11 MAPK1 MAPK3 MARK3 MEK1 MEK2 MKK2 MLK3 NRAS PBP PEBP PEBP1 PHB PHB1 PKS PKS2 PREL1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 PTK1 RAF RAF1 RAFB1 RAP1A RAP1B RARP1 RASK2 RIAM RNF52 SPRK SRC SRC1 TLN TLN1 VCL VWF YWHAB
Defective DPM2 causes CDG-1u	Dolichol phosphate-mannose biosynthesis regulatory protein Dolichol-phosphate mannosyltransferase subunit 1 Dolichol-phosphate mannosyltransferase subunit 3	O60762 O94777 Q9P2X0	DPM1 DPM2 DPM3
G alpha (q) signalling events	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 5-hydroxytryptamine receptor 2A 5-hydroxytryptamine receptor 2B 5-hydroxytryptamine receptor 2C Alpha-1A adrenergic receptor Alpha-1B adrenergic receptor Alpha-1D adrenergic receptor Amyloid-beta precursor protein Angiotensinogen Annexin A1 B1 bradykinin receptor B2 bradykinin receptor Beta-adrenergic receptor kinase 1 Bombesin receptor subtype-3 Chemokine XC receptor 1 Cholecystokinin receptor type A Cholecystokinin Cysteinyl leukotriene receptor 1 Cysteinyl leukotriene receptor 2 Cytokine SCM-1 beta Endothelin receptor type B Endothelin-1 receptor Endothelin-1 Endothelin-2 Endothelin-3 Extracellular calcium-sensing receptor Free fatty acid receptor 1 Free fatty acid receptor 2 Free fatty acid receptor 3 Free fatty acid receptor 4 G protein-coupled receptor kinase 5 G-protein coupled receptor 143 G-protein coupled receptor 39 G-protein coupled receptor 4 G-protein coupled receptor family C group 6 member A Gastrin-releasing peptide receptor Gastrin-releasing peptide Gastrin/cholecystokinin type B receptor Gastrin Glucagon receptor Gonadotropin-releasing hormone receptor Growth hormone secretagogue receptor type 1 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha-15 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Histamine H1 receptor Humanin Hypocretin neuropeptide precursor Kalirin KiSS-1 receptor Kininogen-1 Leukotriene B4 receptor 1 Leukotriene B4 receptor 2 Lymphotactin Lysophosphatidic acid receptor 1 Lysophosphatidic acid receptor 2 Lysophosphatidic acid receptor 3 Lysophosphatidic acid receptor 4 Lysophosphatidic acid receptor 5 Lysophosphatidic acid receptor 6 Melanin-concentrating hormone receptor 1 Melanin-concentrating hormone receptor 2 Melanopsin Metabotropic glutamate receptor 1 Metabotropic glutamate receptor 5 Metastasis-suppressor KiSS-1 Motilin receptor Muscarinic acetylcholine receptor M1 Muscarinic acetylcholine receptor M3 Muscarinic acetylcholine receptor M5 N-formyl peptide receptor 2 Neuromedin-B receptor Neuromedin-B Neuromedin-K receptor Neuromedin-S Neuromedin-U receptor 1 Neuromedin-U receptor 2 Neuromedin-U Neuropeptide FF receptor 1 Neuropeptide FF receptor 2 Neuropeptide S receptor Neuropeptide S Neurotensin receptor type 1 Neurotensin receptor type 2 Neurotensin/neuromedin N Orexigenic neuropeptide QRFP Orexin receptor type 2 Orexin/Hypocretin receptor type 1 Ovarian cancer G-protein coupled receptor 1 Oxytocin receptor Oxytocin-neurophysin 1 P2Y purinoceptor 11 P2Y purinoceptor 1 P2Y purinoceptor 2 P2Y purinoceptor 6 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Platelet-activating factor receptor Pro-FMRFamide-related neuropeptide FF Pro-MCH Pro-glucagon Pro-thyrotropin-releasing hormone Probable G-protein coupled receptor 132 Progonadoliberin-1 Progonadoliberin-2 Prokineticin receptor 1 Prokineticin receptor 2 Prokineticin-1 Prokineticin-2 Promotilin Prostaglandin E2 receptor EP1 subtype Prostaglandin F2-alpha receptor Protachykinin-1 Proteinase-activated receptor 1 Proteinase-activated receptor 2 Proteinase-activated receptor 3 Proteinase-activated receptor 4 Prothrombin Psychosine receptor Putative P2Y purinoceptor 10 Putative gonadotropin-releasing hormone II receptor Pyroglutamylated RF-amide peptide receptor Regulator of G-protein signaling 13 Regulator of G-protein signaling 16 Regulator of G-protein signaling 17 Regulator of G-protein signaling 18 Regulator of G-protein signaling 19 Regulator of G-protein signaling 1 Regulator of G-protein signaling 21 Regulator of G-protein signaling 2 Regulator of G-protein signaling 3 Regulator of G-protein signaling 4 Regulator of G-protein signaling 5 Regulator of G-protein signaling protein-like Rho guanine nucleotide exchange factor 25 Serum amyloid A-1 protein Substance-K receptor Substance-P receptor Tachykinin-3 Thromboxane A2 receptor Thyrotropin-releasing hormone receptor Triple functional domain protein Type-1 angiotensin II receptor Tyrosine-protein kinase BTK Uracil nucleotide/cysteinyl leukotriene receptor Urotensin-2 receptor Urotensin-2 Urotensin-2B Vasopressin V1a receptor Vasopressin V1b receptor Vasopressin-neurophysin 2-copeptin	A5PLK6 O00254 O00398 O00459 O14610 O14775 O14842 O14843 O14921 O15130 O15492 O15539 O15552 O43193 O43194 O43555 O43612 O43613 O43614 O60229 O60262 O75962 O95399 O95665 O95837 P00734 P01019 P01042 P01148 P01178 P01185 P01275 P01350 P04083 P05067 P05305 P06307 P07492 P08912 P08949 P0C0P6 P0DJI8 P11229 P12872 P14138 P16520 P20309 P20366 P20382 P20396 P20800 P21452 P21731 P24530 P25090 P25098 P25100 P25101 P25103 P25105 P25116 P27986 P28223 P28335 P28336 P29371 P29992 P30411 P30550 P30556 P30559 P30679 P30968 P30989 P30990 P32238 P32239 P32247 P34947 P34981 P34995 P35348 P35367 P35368 P37288 P41180 P41220 P41231 P41594 P41595 P42336 P43088 P43657 P46093 P46094 P46663 P47871 P47900 P47901 P47992 P48645 P49795 P49796 P49798 P50148 P50150 P50151 P51810 P55085 P58294 P59768 P61952 P62873 P62879 P63211 P63215 P63218 P83859 Q00722 Q01970 Q06187 Q08116 Q13255 Q13304 Q15077 Q15147 Q15722 Q15726 Q15743 Q2M5E4 Q5H8A3 Q5NUL3 Q5T6X5 Q6W5P4 Q765I0 Q86VW2 Q8IVG9 Q8IYL9 Q8NFJ6 Q8TCW9 Q92569 Q92633 Q92847 Q969F8 Q969V1 Q96G91 Q96P65 Q96P88 Q96RI0 Q99677 Q99705 Q9GZQ4 Q9GZQ6 Q9H1C0 Q9HAV0 Q9HB89 Q9HBW0 Q9HC23 Q9NPC1 Q9NQ66 Q9NS28 Q9NS75 Q9P2W3 Q9UBD3 Q9UBI6 Q9UBY5 Q9UGC6 Q9UHF0 Q9UHM6 Q9UK08 Q9UKP6 Q9UNW8 Q9Y271 Q9Y5X5	1R20 A4 AD1 ADRA1A ADRA1B ADRA1C ADRA1D ADRBK1 AGMX1 AGT AGTR1 AGTR1A AGTR1B ANX1 ANXA1 APP ARHGEF25 ARVP AT2R1 AT2R1B ATK AVP AVPR1 AVPR1A AVPR1B AVPR3 AXOR12 BARK BARK1 BDK BDKRB1 BDKRB2 BKR2 BL34 BLT BLT1 BLT2R BLTR BLTR2 BPK BRADYB1 BRS3 BTK BV8 CASR CCK CCKAR CCKBR CCKRA CCKRB CCXCR1 CF2R CHRM1 CHRM3 CHRM5 CMKRL1 CYSLT1 CYSLT2 CYSLT2R CYSLTR1 CYSLTR2 DUET DUO EDG2 EDG4 EDG7 EDN1 EDN2 EDN3 EDNRA EDNRB ETA ETRA ETRB F2 F2R F2RL1 F2RL2 F2RL3 FFA2 FFAR1 FFAR2 FFAR3 FFAR4 FPR2 FPRH1 FPRL1 G0S8 G2A GA11 GAIP GAQ GAS GAST GCG GCGR GEFT GHSR GNA11 GNA14 GNA15 GNA16 GNAI3IP GNAQ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GNRH GNRH1 GNRH2 GNRHR GNRHR2 GPCR43 GPR103 GPR11 GPR120 GPR129 GPR132 GPR14 GPR143 GPR145 GPR147 GPR154 GPR16 GPR17 GPR23 GPR24 GPR38 GPR39 GPR4 GPR40 GPR41 GPR43 GPR5 GPR54 GPR65 GPR66 GPR68 GPR73 GPR73L1 GPR74 GPR92 GPR93 GPRA GPRC1A GPRC1E GPRC2A GPRC6A GPRK5 GRB1 GRH GRHR GRK2 GRK5 GRM1 GRM5 GRP GRPR HAPIP HCRT HCRTR1 HCRTR2 HN HRH1 HTR1C HTR2 HTR2A HTR2B HTR2C IER1 KALRN KIAA0581 KISS1 KISS1R KNG KNG1 LHRH LPA1 LPA2 LPA3 LPA4 LPAR1 LPAR2 LPAR3 LPAR4 LPAR5 LPAR6 LPC1 LTB4R LTB4R2 LTN LXA4R MCH MCHR1 MCHR2 MGLUR1 MGLUR5 MLN MLNR MOP MT-RNR2 MTLR MTLR1 NK1R NK2R NK3R NKA NKNA NKNAR NKNB NMB NMBR NMS NMU NMU2R NMUR1 NMUR2 NPFF NPFF1 NPFF2 NPFFR1 NPFFR2 NPGPR NPS NPSR1 NTRR NTS NTSR1 NTSR2 O3FAR1 OA1 OGR1 OPN4 OT OX OXT OXTR P2RU1 P2RY1 P2RY10 P2RY11 P2RY2 P2RY5 P2RY6 P2RY7 P2RY9 PAFR PAR1 PAR2 PAR3 PAR4 PCAR1 PGR14 PGR4 PIK3CA PIK3R1 PIK3R2 PIK3R3 PKR1 PKR2 PLCB1 PLCB2 PLCB3 PLCB4 PMCH PPORX PPOX PROK1 PROK2 PROKR1 PROKR2 PTAFR PTGER1 PTGFR QRFP QRFPR RGS1 RGS13 RGS16 RGS17 RGS18 RGS19 RGS2 RGS21 RGS3 RGS4 RGS5 RGSL RGSL1 RGSL2 RGSR RGSZ2 SAA1 SCYC1 SCYC2 SERPINA8 SLC1 SLT TAC1 TAC1R TAC2 TAC2R TAC3 TAC3R TACR1 TACR2 TACR3 TBXA2R TDAG8 TGR1 TR TRAD TRH TRHR TRIO URP UTS2 UTS2B UTS2D UTS2R VP VPR3 XCL1 XCL2 XCR1
IFNG signaling activates MAPKs	Interferon gamma receptor 1 Interferon gamma receptor 2 Interferon gamma Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 RAF proto-oncogene serine/threonine-protein kinase Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2	O60674 P01579 P04049 P15260 P23458 P27361 P28482 P38484	ERK1 ERK2 IFNG IFNGR1 IFNGR2 IFNGT1 JAK1 JAK1A JAK1B JAK2 MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 RAF RAF1
Heme biosynthesis	5-aminolevulinate synthase, erythroid-specific, mitochondrial 5-aminolevulinate synthase, non-specific, mitochondrial Albumin Broad substrate specificity ATP-binding cassette transporter ABCG2 Delta-aminolevulinic acid dehydratase Ferrochelatase, mitochondrial Heme A synthase COX15 Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial Porphobilinogen deaminase Protoheme IX farnesyltransferase, mitochondrial Protoporphyrinogen oxidase Uroporphyrinogen decarboxylase Uroporphyrinogen-III synthase	P02768 P06132 P08397 P10746 P13196 P13716 P22557 P22830 P36551 P50336 Q12887 Q7KZN9 Q9UNQ0	ABCG2 ABCP ALAD ALAS1 ALAS2 ALAS3 ALASE ALASH ALB ASB BCRP BCRP1 COX10 COX15 CPO CPOX CPX FECH HMBS MXR PBGD PPOX UPS UROD UROS
G alpha (z) signalling events	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein G(t) subunit alpha-3 Guanine nucleotide-binding protein G(z) subunit alpha Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Protein kinase C alpha type Protein kinase C beta type Protein kinase C delta type Protein kinase C epsilon type Protein kinase C eta type Protein kinase C gamma type Protein kinase C theta type Regulator of G-protein signaling 16 Regulator of G-protein signaling 17 Regulator of G-protein signaling 19 Regulator of G-protein signaling 20 Regulator of G-protein signaling 4 Regulator of G-protein signaling protein-like	A5PLK6 A8MTJ3 O14610 O14775 O15492 O43306 O60262 O60266 O60503 O76081 O95622 P04899 P05129 P05771 P08754 P08913 P16520 P17252 P18089 P18825 P19086 P24723 P40145 P49795 P49798 P50150 P50151 P51828 P59768 P61952 P62873 P62879 P63092 P63096 P63211 P63215 P63218 Q02156 Q04759 Q05655 Q08462 Q08828 Q5JWF2 Q8NFM4 Q9HAV0 Q9P2W3 Q9UBI6 Q9UGC6 Q9UK08	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADRA2A ADRA2B ADRA2C ADRA2L1 ADRA2L2 ADRA2R ADRA2RL1 ADRA2RL2 ADRAR GAIP GNAI1 GNAI2 GNAI2B GNAI3 GNAI3IP GNAS GNAS1 GNAT3 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GSP KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 PKCA PKCB PKCD PKCE PKCG PKCL PRKACA PRKCA PRKCB PRKCB1 PRKCD PRKCE PRKCG PRKCH PRKCL PRKCQ PRKCT RGS16 RGS17 RGS19 RGS20 RGS4 RGSL RGSL1 RGSL2 RGSR RGSZ1 RGSZ2 ZGAP1
Translesion synthesis by REV1	DNA polymerase zeta catalytic subunit DNA repair protein REV1 Mitotic spindle assembly checkpoint protein MAD2B Polyubiquitin-B Polyubiquitin-C Proliferating cell nuclear antigen Replication factor C subunit 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O60673 P0CG47 P0CG48 P12004 P15927 P27694 P35244 P35249 P35250 P35251 P40937 P40938 P62979 P62987 Q9UBZ9 Q9UI95	MAD2B MAD2L2 PCNA POLZ REPA1 REPA2 REPA3 REV1 REV1L REV3 REV3L REV7 RFC1 RFC140 RFC2 RFC3 RFC4 RFC5 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Defective SLC34A2 causes PALM	Sodium-dependent phosphate transport protein 2B	O95436	SLC34A2
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells	CREB-binding protein Core-binding factor subunit beta Galectin-3 Granulocyte-macrophage colony-stimulating factor Protein kinase C beta type Runt-related transcription factor 1	P04141 P05771 P17931 Q01196 Q13951 Q92793	AML1 CBFA2 CBFB CBP CREBBP CSF2 GMCSF LGALS3 MAC2 PKCB PRKCB PRKCB1 RUNX1
Growth hormone receptor signaling	Chorionic somatomammotropin hormone 1 Cytokine-inducible SH2-containing protein Disintegrin and metalloproteinase domain-containing protein 17 Growth hormone receptor Growth hormone variant Insulin receptor substrate 1 Insulin receptor substrate 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Prolactin receptor Prolactin Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Somatotropin Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 2 Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn Tyrosine-protein phosphatase non-receptor type 1 Tyrosine-protein phosphatase non-receptor type 6	O14508 O14543 O15524 O60674 P01236 P01241 P01242 P07948 P0DML2 P10912 P16471 P18031 P27361 P28482 P29350 P35568 P40763 P42224 P42229 P51692 P78536 Q9NSE2 Q9Y4H2	ADAM17 APRF CIS2 CIS3 CISH CSH1 CSVP ERK1 ERK2 G18 GH1 GH2 GHR HCP IRS1 IRS2 JAK2 JTK8 LYN MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 PRL PRLR PTP1B PTP1C PTPN1 PTPN6 SOCS1 SOCS2 SOCS3 SSI1 SSI2 SSI3 STAT1 STAT3 STAT5 STAT5A STAT5B STATI2 TACE TIP3
Biosynthesis of D-series resolvins	15-hydroxyprostaglandin dehydrogenase [NAD(+)] Leukotriene A-4 hydrolase Polyunsaturated fatty acid 5-lipoxygenase	P09917 P09960 P15428	ALOX5 HPGD LOG5 LTA4 LTA4H PGDH1 SDR36C1
HCN channels	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4	O60741 Q9P1Z3 Q9UL51 Q9Y3Q4	BCNG1 BCNG2 HCN1 HCN2 HCN3 HCN4 KIAA1535
Signaling by FGFR3 fusions in cancer	Fibroblast growth factor receptor 3	P22607	FGFR3 JTK4
TFAP2 (AP-2) family regulates transcription of cell cycle factors	Cyclin-dependent kinase inhibitor 1 Lysine-specific demethylase 5B Myc proto-oncogene protein Transcription factor AP-2 gamma Transcription factor AP-2-alpha	P01106 P05549 P38936 Q92754 Q9UGL1	AP2TF BHLHE39 CAP20 CDKN1 CDKN1A CIP1 JARID1B KDM5B MDA6 MYC PIC1 PLU1 RBBP2H1 SDI1 TFAP2 TFAP2A TFAP2C WAF1

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