GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **1201 - 1225** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol
Retrograde transport at the Trans-Golgi-Network	ADP-ribosylation factor-like protein 1 ADP-ribosylation factor-related protein 1 Alpha-soluble NSF attachment protein Arfaptin-2 Beta-soluble NSF attachment protein Cation-dependent mannose-6-phosphate receptor Cation-independent mannose-6-phosphate receptor Conserved oligomeric Golgi complex subunit 1 Conserved oligomeric Golgi complex subunit 2 Conserved oligomeric Golgi complex subunit 3 Conserved oligomeric Golgi complex subunit 4 Conserved oligomeric Golgi complex subunit 5 Conserved oligomeric Golgi complex subunit 6 Conserved oligomeric Golgi complex subunit 7 Conserved oligomeric Golgi complex subunit 8 GRIP and coiled-coil domain-containing protein 1 GRIP and coiled-coil domain-containing protein 2 Gamma-soluble NSF attachment protein Golgin subfamily A member 1 Golgin subfamily A member 4 Guanine nucleotide exchange factor subunit RIC1 N-alpha-acetyltransferase 30 N-alpha-acetyltransferase 35, NatC auxiliary subunit N-alpha-acetyltransferase 38, NatC auxiliary subunit Perilipin-3 Protein SYS1 homolog RAB6A-GEF complex partner protein 2 Rab9 effector protein with kelch motifs Ras-related protein Rab-43 Ras-related protein Rab-6A Ras-related protein Rab-6B Ras-related protein Rab-9A Ras-related protein Rab-9B Rho-related BTB domain-containing protein 3 Short coiled-coil protein Syntaxin-10 Syntaxin-16 Syntaxin-6 TATA element modulatory factor Trans-Golgi network integral membrane protein 2 USP6 N-terminal-like protein Vacuolar protein sorting-associated protein 51 homolog Vacuolar protein sorting-associated protein 52 homolog Vacuolar protein sorting-associated protein 53 homolog Vacuolar protein sorting-associated protein 54 Vesicle transport through interaction with t-SNAREs homolog 1A Vesicle-associated membrane protein 3 Vesicle-associated membrane protein 4 Vesicle-fusing ATPase	O14662 O43493 O43752 O60499 O60664 O75379 O94955 P11717 P20340 P20645 P40616 P46459 P51151 P53365 P54920 P82094 P83436 Q13439 Q13795 Q14746 Q147X3 Q15836 Q4ADV7 Q5VIR6 Q5VZE5 Q7Z6M1 Q86YS6 Q8IWJ2 Q8N1B4 Q8N2H4 Q8WTW3 Q92546 Q92738 Q92805 Q96AJ9 Q96CN9 Q96JB2 Q96MW5 Q99747 Q9BRA0 Q9H115 Q9H9E3 Q9NP90 Q9NRW1 Q9P1Q0 Q9UID3 Q9UIL1 Q9UP83 Q9Y2V7	ANG2 ARA160 ARFIP2 ARFRP1 ARL1 ARP1 C11orf2 C11orf3 C14orf35 C20orf169 CIP150 COG1 COG2 COG3 COG4 COG5 COG6 COG7 COG8 EGAP FFR GCC1 GCC2 GOLGA1 GOLGA4 GOLTC1 GTC90 HCC8 IGF2R KIAA0019 KIAA0258 KIAA0336 KIAA0878 KIAA1134 KIAA1381 KIAA1432 LDLB LDLC LSMD1 M6PR M6PRBP1 MAK10 MAK3 MAK31 MPR46 MPRD MPRI NAA30 NAA35 NAA38 NAPA NAPB NAPG NAT12 NSF PFAAP2 PLIN3 POR1 RAB41 RAB43 RAB6 RAB6A RAB6B RAB9 RAB9A RAB9B RAB9L RAB9P40 RABEPK RANBP2L4 RGP1 RHOBTB3 RIC1 SACM2L SCOC SCOCO SEC34 SNAPA SNAPB SNAPG STX10 STX16 STX6 SYB3 SYN10 SYS1 TGN46 TGN51 TGOLN2 TIP47 TMF1 USP6NL VAMP3 VAMP4 VPS51 VPS52 VPS53 VPS54 VTI1A
SHC1 events in ERBB2 signaling	Epidermal growth factor receptor GTPase HRas GTPase NRas Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protein kinase C alpha type Protein kinase C delta type Protein kinase C epsilon type Receptor tyrosine-protein kinase erbB-2 SHC-transforming protein 1 Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 12	O14511 O14944 P00533 P01111 P01112 P01133 P04626 P17252 P29353 P35070 P56975 Q02156 Q02297 Q05209 Q05655 Q07889 Q8WWG1 Q99075	BTC DTR DTS EGF EGFR ERBB ERBB1 ERBB2 EREG GGF HBEGF HEGFL HER1 HER2 HGL HRAS HRAS1 HRGA MLN19 NDF NEU NGL NRAS NRG1 NRG2 NRG3 NRG4 NTAK PKCA PKCD PKCE PRKACA PRKCA PRKCD PRKCE PTPN12 SHC SHC1 SHCA SMDF SOS1
XBP1(S) activates chaperone genes	ADP-ribosylation factor GTPase-activating protein 1 ATP-dependent DNA helicase DDX11 Alpha-adducin CXXC-type zinc finger protein 1 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 Cullin-7 Cytosolic phospholipase A2 beta DnaJ homolog subfamily B member 11 DnaJ homolog subfamily B member 9 DnaJ homolog subfamily C member 3 Dynactin subunit 1 E3 ubiquitin-protein ligase synoviolin ER degradation-enhancing alpha-mannosidase-like protein 1 ER lumen protein-retaining receptor 3 Exostosin-like 1 Exostosin-like 2 Exostosin-like 3 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 Glycogen synthase kinase-3 alpha Golgi SNAP receptor complex member 2 Guanine nucleotide-exchange factor SEC12 Hepatoma-derived growth factor Hypoxia up-regulated protein 1 Kelch domain-containing protein 3 Myeloid-derived growth factor Peptidyl-prolyl cis-trans isomerase FKBP14 Prelamin-A/C Protein YIF1A Protein disulfide-isomerase A5 Protein disulfide-isomerase A6 Protein transport protein Sec31A Putative deoxyribonuclease TATDN2 SHC-transforming protein 1 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Signal recognition particle receptor subunit alpha Signal recognition particle receptor subunit beta Stress-associated endoplasmic reticulum protein 1 Sulfotransferase 1A3 Talin-1 Testis-specific Y-encoded-like protein 2 Translocon-associated protein subunit alpha Tripeptidyl-peptidase 1 V-type proton ATPase subunit d 1 Very long-chain specific acyl-CoA dehydrogenase, mitochondrial WD repeat domain phosphoinositide-interacting protein 1 Wolframin Zinc finger and BTB domain-containing protein 17	O14595 O14653 O14773 O43731 O43909 O76024 O94979 O95070 P02545 P08240 P0C869 P0DMM9 P29353 P35611 P43307 P49748 P49840 P51858 P61421 Q06210 Q13105 Q13217 Q14203 Q14554 Q14999 Q15084 Q15173 Q5MNZ9 Q86TM6 Q8N6T3 Q92611 Q92935 Q93075 Q969H8 Q96FC9 Q9BQ90 Q9H2G4 Q9HCU5 Q9NWM8 Q9P0U4 Q9UBQ6 Q9UBS3 Q9UBS4 Q9Y490 Q9Y4L1 Q9Y5M8 Q9Y6X1	54TM ACADVL ADD1 ADDA ARF1GAP ARFGAP1 ATP6D ATP6V0D1 C19orf10 CDA1 CFP1 CGBP CHL1 CHLR1 CLN2 CTDSP2 CUL7 CXXC1 DCTN1 DDX11 DENTT DNAJB11 DNAJB9 DNAJC3 EDEM EDEM1 EDJ ERD23 ERJ3 ERP5 EXTL EXTL1 EXTL1L EXTL2 EXTL3 EXTR1 EXTR2 FKBP14 FKBP22 GFAT GFPT GFPT1 GOSR2 GRP170 GS27 GSK3A HDGF HDJ9 HMG1L2 HRD1 HSPH4 HYIF1P HYOU1 KDELR3 KIAA0076 KIAA0212 KIAA0218 KIAA0519 KIAA0905 KIAA1027 KIAA1810 KLHDC3 KRG2 LMN1 LMNA MDG1 MIZ1 MYDGF NIF2 ORP150 OS4 P5 P58IPK PCCX1 PDIA5 PDIA6 PDIR PEAS PHF18 PLA2G4B PPP2R5B PREB PRKRI RAMP4 SCP2 SEC12 SEC31A SEC31L1 SERP1 SHC SHC1 SHCA SRPR SRPRA SRPRB SSR1 STM SULT1A3 SYVN1 TATDN2 TLN TLN1 TPP1 TRAPA TSPX TSPYL2 TXNDC7 VLCAD VPATPD WFS1 WIPI1 WIPI49 YIF1 YIF1A ZBTB17 ZNF151 ZNF60
Breakdown of the nuclear lamina	Caspase-6 Lamin-B1	P20700 P55212	CASP6 LMN2 LMNB LMNB1 MCH2
IRAK1 recruits IKK complex	E3 ubiquitin-protein ligase pellino homolog 1 E3 ubiquitin-protein ligase pellino homolog 2 E3 ubiquitin-protein ligase pellino homolog 3 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 receptor-associated kinase 1 NF-kappa-B essential modulator TNF receptor-associated factor 6 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1	O14920 O15111 P51617 P61088 Q13404 Q8N2H9 Q96FA3 Q9HAT8 Q9Y4K3 Q9Y6K9	BLU CHUK CROC1 FIP3 IKBKB IKBKG IKKA IKKB IRAK IRAK1 NEMO PELI1 PELI2 PELI3 PRISM RNF85 TCF16 TRAF6 UBE2N UBE2V UBE2V1 UEV1
Resolution of AP sites via the multiple-nucleotide patch replacement pathway	DNA polymerase beta DNA repair nuclease/redox regulator APEX1	P06746 P27695	APE APE1 APEX APEX1 APX HAP1 POLB REF1
Toll Like Receptor 3 (TLR3) Cascade	TIR domain-containing adapter molecule 1 Toll-like receptor 3	O15455 Q8IUC6	PRVTIRB TICAM1 TLR3 TRIF
Interleukin-7 signaling	Bromodomain and WD repeat-containing protein 1 Cytokine receptor common subunit gamma Cytokine receptor-like factor 2 Cytokine-inducible SH2-containing protein Hepatocyte growth factor Histone H3.1 Histone H3.2 Insulin receptor substrate 1 Insulin receptor substrate 2 Interleukin-7 receptor subunit alpha Interleukin-7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 2 Thymic stromal lymphopoietin Transcription activator BRG1 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK3 V(D)J recombination-activating protein 1 V(D)J recombination-activating protein 2	O00459 O14508 O15524 P13232 P14210 P15918 P16871 P23458 P27986 P31785 P35568 P40763 P42229 P51532 P51692 P52333 P55895 P68431 Q71DI3 Q92569 Q969D9 Q9HC73 Q9NSE2 Q9NSI6 Q9Y4H2	APRF BAF190A BRG1 BRWD1 C21orf107 CIS2 CISH CRL2 CRLF2 G18 GRB1 H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM HGF HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST2H3A HIST2H3C HIST2H3D HPTA IL2RG IL7 IL7R ILXR IRS1 IRS2 JAK1 JAK1A JAK1B JAK3 PIK3R1 PIK3R2 PIK3R3 RAG1 RAG2 RNF74 SMARCA4 SNF2B SNF2L4 SOCS1 SOCS2 SSI1 SSI2 STAT3 STAT5 STAT5A STAT5B STATI2 TIP3 TSLP TSLPR WDR9
Release	Hemagglutinin Matrix protein 1 Matrix protein 2 Neuraminidase Nuclear export protein Nucleoprotein Polymerase acidic protein Polymerase basic protein 2 RNA-directed RNA polymerase catalytic subunit	P03428 P03431 P03433 P03452 P03466 P03468 P03485 P03508 P06821	HA M NA NP NS PA PB1 PB2
TBC/RABGAPs	ADP-ribosylation factor 6 ADP-ribosylation factor-binding protein GGA1 ADP-ribosylation factor-binding protein GGA2 ADP-ribosylation factor-binding protein GGA3 Carabin Gamma-aminobutyric acid receptor-associated protein-like 2 Gamma-aminobutyric acid receptor-associated protein Genome polyprotein Hamartin Microtubule-associated proteins 1A/1B light chain 3B Optineurin Rab GTPase-activating protein 1 Rab GTPase-binding effector protein 1 Rab5 GDP/GTP exchange factor Ras-related protein Rab-11A Ras-related protein Rab-11B Ras-related protein Rab-33A Ras-related protein Rab-33B Ras-related protein Rab-35 Ras-related protein Rab-4A Ras-related protein Rab-5A Ras-related protein Rab-5B Ras-related protein Rab-5C Ras-related protein Rab-6A Ras-related protein Rab-6B Ras-related protein Rab-7a Ras-related protein Rab-7b Ras-related protein Rab-8A Ras-related protein Rab-8B Serine/threonine-protein kinase ULK1 Synaptotagmin-like protein 1 TBC1 domain family member 10A TBC1 domain family member 10B TBC1 domain family member 13 TBC1 domain family member 14 TBC1 domain family member 15 TBC1 domain family member 16 TBC1 domain family member 17 TBC1 domain family member 20 TBC1 domain family member 24 TBC1 domain family member 25 TBC1 domain family member 2A TBC1 domain family member 3 TBC1 domain family member 7 Tuberin	O75385 O95166 P20338 P20339 P20340 P27958 P49815 P51148 P51149 P60520 P61006 P61020 P62330 P62491 Q14088 Q15276 Q15286 Q15907 Q3MII6 Q4KMP7 Q8IV04 Q8IYJ3 Q8IZP1 Q8TBP0 Q8TC07 Q92574 Q92930 Q96AH8 Q96BZ9 Q96CV9 Q9BXI6 Q9BYX2 Q9GZQ8 Q9H082 Q9HA65 Q9NRW1 Q9NVG8 Q9NZ52 Q9P0N9 Q9P2M4 Q9UJ41 Q9UJY4 Q9UJY5 Q9ULP9 Q9Y3P9	ARF6 C20orf140 EPI64 FIP2 FLC3A FLC3B GABARAP GABARAPL2 GEF2 GGA1 GGA2 GGA3 GLC1E HIP7 HYPL KIAA0154 KIAA0243 KIAA0722 KIAA1080 KIAA1171 KIAA1322 MAP1ALC3 MAP1LC3B MEL NRP OATL1 OPTN PARIS1 PP8997 PRC17 RAB11 RAB11A RAB11B RAB1C RAB33A RAB33B RAB35 RAB4 RAB4A RAB5 RAB5A RAB5B RAB5C RAB5EP RAB6 RAB6A RAB6B RAB7 RAB7A RAB7B RAB8 RAB8A RAB8B RABEP1 RABEX5 RABGAP1 RABGEF1 RABL RABPT5 RABPT5A RABS10 RAY SLP1 SYTL1 TBC1D10 TBC1D10A TBC1D10B TBC1D10C TBC1D13 TBC1D14 TBC1D15 TBC1D16 TBC1D17 TBC1D2 TBC1D20 TBC1D24 TBC1D25 TBC1D2A TBC1D3 TBC1D3A TBC1D7 TBC7 TSC TSC1 TSC2 TSC4 ULK1 YPT3
Unwinding of DNA	Cell division control protein 45 homolog DNA helicase MCM8 DNA replication complex GINS protein PSF1 DNA replication complex GINS protein PSF2 DNA replication complex GINS protein PSF3 DNA replication complex GINS protein SLD5 DNA replication licensing factor MCM2 DNA replication licensing factor MCM3 DNA replication licensing factor MCM4 DNA replication licensing factor MCM5 DNA replication licensing factor MCM6 DNA replication licensing factor MCM7	O75419 P25205 P33991 P33992 P33993 P49736 Q14566 Q14691 Q9BRT9 Q9BRX5 Q9UJA3 Q9Y248	BM28 C20orf154 CCNL1 CDC21 CDC45 CDC45L CDC45L2 CDC46 CDC47 CDCL1 GINS1 GINS2 GINS3 GINS4 KIAA0030 KIAA0186 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MCM8 PSF1 PSF2 PSF3 SLD5
Regulation of signaling by NODAL	Activin receptor type-1B Activin receptor type-1C Activin receptor type-2A Activin receptor type-2B Cerberus Cryptic protein DAN domain family member 5 Left-right determination factor 1 Left-right determination factor 2 Nodal homolog Protein Cripto Putative protein CRIPTO3	O00292 O75610 O95813 P0CG37 P13385 P27037 P36896 P51864 Q13705 Q8N907 Q8NER5 Q96S42	ACVR1B ACVR1C ACVR2 ACVR2A ACVR2B ACVRLK4 ALK4 ALK7 CER1 CER2 CFC1 CKTSF1B3 CRIPTO CRIPTO-1 CRIPTO-3 CRIPTO3 DAND4 DAND5 EBAF GREM3 LEFTA LEFTB LEFTY1 LEFTY2 LEFTYA LEFTYB NODAL SP1 TDGF1 TDGF1P3 TDGF2 TDGF3 TGFB4
FRS-mediated FGFR4 signaling	Beta-klotho Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 19 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 GTPase HRas GTPase NRas Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O43320 O43559 O76093 O95750 P01111 P01112 P05230 P08620 P09038 P10767 P22455 P31371 Q06124 Q07889 Q86Z14 Q8WU20 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF9 FGFA FGFB FGFR4 FRS2 FRS3 HRAS HRAS1 HST HST2 HSTF1 HSTF2 HYPF JTK2 KLB KS3 NRAS PTP2C PTPN11 SHPTP2 SOS1 TKF
Generation of second messenger molecules	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 Actin nucleation-promoting factor WAS Ena/VASP-like protein FYN-binding protein 1 GRB2-related adapter protein 2 HLA class II histocompatibility antigen, DP alpha 1 chain HLA class II histocompatibility antigen, DP beta 1 chain HLA class II histocompatibility antigen, DQ alpha 1 chain HLA class II histocompatibility antigen, DQ alpha 2 chain HLA class II histocompatibility antigen, DQ beta 1 chain HLA class II histocompatibility antigen, DQ beta 2 chain HLA class II histocompatibility antigen, DR alpha chain HLA class II histocompatibility antigen, DR beta 3 chain HLA class II histocompatibility antigen, DR beta 4 chain HLA class II histocompatibility antigen, DR beta 5 chain HLA class II histocompatibility antigen, DRB1 beta chain Immunoglobulin superfamily member 2 Linker for activation of T-cells family member 1 Lymphocyte cytosolic protein 2 Protein enabled homolog SH2/SH3 adapter protein NCK1 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 T cell receptor alpha chain constant T cell receptor alpha variable 19 T cell receptor alpha variable 29/delta variable 5 T cell receptor alpha variable 8-4 T cell receptor beta constant 1 T cell receptor beta variable 12-3 T cell receptor beta variable 7-9 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD4 Tyrosine-protein kinase ITK/TSK Tyrosine-protein kinase Lck Tyrosine-protein kinase ZAP-70 Vasodilator-stimulated phosphoprotein	A0A0A6YYK7 O15117 O43561 O75791 O75914 P01730 P01733 P01737 P01848 P01850 P01903 P01906 P01909 P01911 P01920 P04234 P04435 P04437 P04440 P05538 P06239 P07766 P09693 P13762 P16333 P16885 P19174 P20036 P42768 P43403 P50552 P79483 Q08881 Q13094 Q13153 Q13177 Q30154 Q8N8S7 Q93033 Q9UI08	CD101 CD3D CD3E CD3G CD4 EMT ENAH EVL EWI101 FYB FYB1 GADS GRAP2 GRB2L GRID HLA-DP1A HLA-DP1B HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB HLA-DQB1 HLA-DQB2 HLA-DRA HLA-DRA1 HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 HLA-DXA HLA-DXB HLASB IGSF2 IMD2 ITK LAT LCK LCP2 LYK MENA NCK NCK1 OPHN3 PAK1 PAK2 PAK3 PLC1 PLCG1 PLCG2 RNB6 SLAP130 SRK T3D T3E T3G TCRA TCRBV12S3 TCRBV8S1 TRAC TRAV19 TRAV29DV5 TRAV8-4 TRBC1 TRBV12-3 TRBV7-9 V7 VASP WAS ZAP70
Signaling by Insulin receptor	Insulin receptor Insulin	P01308 P06213	INS INSR
Signaling by ERBB4	Disks large homolog 4 Epidermal growth factor receptor Gamma-aminobutyric acid receptor subunit alpha-1 Gamma-aminobutyric acid receptor subunit beta-1 Gamma-aminobutyric acid receptor subunit beta-2 Gamma-aminobutyric acid receptor subunit beta-3 Gamma-aminobutyric acid receptor subunit gamma-2 Gamma-aminobutyric acid receptor subunit gamma-3 Gamma-aminobutyric acid receptor subunit theta Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor	O14511 O14944 P00533 P01133 P14867 P18505 P18507 P28472 P35070 P47870 P56975 P78352 Q02297 Q8WWG1 Q99075 Q99928 Q9UN88	BTC DLG4 DTR DTS EGF EGFR ERBB ERBB1 EREG GABRA1 GABRB1 GABRB2 GABRB3 GABRG2 GABRG3 GABRQ GGF HBEGF HEGFL HER1 HGL HRGA NDF NRG1 NRG2 NRG3 NRG4 NTAK PSD95 SMDF
Highly calcium permeable nicotinic acetylcholine receptors	Acetylcholine receptor subunit alpha Neuronal acetylcholine receptor subunit alpha-2 Neuronal acetylcholine receptor subunit alpha-3 Neuronal acetylcholine receptor subunit alpha-4 Neuronal acetylcholine receptor subunit alpha-5 Neuronal acetylcholine receptor subunit alpha-6 Neuronal acetylcholine receptor subunit beta-2 Neuronal acetylcholine receptor subunit beta-3 Neuronal acetylcholine receptor subunit beta-4	P02708 P17787 P30532 P30926 P32297 P43681 Q05901 Q15822 Q15825	ACHRA CHNRA CHRNA1 CHRNA2 CHRNA3 CHRNA4 CHRNA5 CHRNA6 CHRNB2 CHRNB3 CHRNB4 NACHRA3 NACHRA5 NACRA4
Acetylcholine Neurotransmitter Release Cycle	Choline O-acetyltransferase Complexin-1 High affinity choline transporter 1 Liprin-alpha-1 Liprin-alpha-2 Liprin-alpha-3 Liprin-alpha-4 Peripheral-type benzodiazepine receptor-associated protein 1 Protein unc-13 homolog B Ras-related protein Rab-3A Regulating synaptic membrane exocytosis protein 1 Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Vesicle-associated membrane protein 2 Vesicular acetylcholine transporter	O14795 O14810 O75145 O75334 O75335 O95153 P20336 P21579 P28329 P60880 P63027 Q13136 Q16572 Q16623 Q86UR5 Q9GZV3	BZRAP1 CHAT CHT1 CPLX1 KIAA0340 KIAA0612 KIAA0654 KIAA0897 LIP1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 RAB3A RAB3IP2 RBP1 RIM1 RIMBP1 RIMS1 SLC18A3 SLC5A7 SNAP SNAP25 STX1 STX1A SVP65 SYB2 SYT SYT1 TSPOAP1 UNC13 UNC13B VACHT VAMP2
CLEC7A/inflammasome pathway	Apoptosis-associated speck-like protein containing a CARD Caspase-8 Interleukin-1 beta Mucosa-associated lymphoid tissue lymphoma translocation protein 1 Nuclear factor NF-kappa-B p105 subunit Transcription factor p65	P01584 P19838 Q04206 Q14790 Q9UDY8 Q9ULZ3	ASC CARD5 CASP8 IL1B IL1F2 MALT1 MCH5 MLT NFKB1 NFKB3 PYCARD RELA TMS1
Peptide hormone biosynthesis	Neuroendocrine convertase 1 Pro-opiomelanocortin	P01189 P29120	NEC1 PCSK1 POMC
Glucagon signaling in metabolic regulation	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Glucagon receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein subunit beta-4 Pro-glucagon	O43306 O60262 O60266 O60503 O95622 P01275 P16520 P40145 P47871 P50150 P50151 P51828 P59768 P61952 P62873 P62879 P63092 P63215 P63218 Q08462 Q08828 Q5JWF2 Q8NFM4 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 GCG GCGR GNAS GNAS1 GNB1 GNB2 GNB3 GNB4 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT10 GNGT11 GNGT3 GNGT4 GNGT5 GNGT7 GNGT9 GSP KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060
Tyrosine catabolism	4-hydroxyphenylpyruvate dioxygenase Fumarylacetoacetase Homogentisate 1,2-dioxygenase Maleylacetoacetate isomerase Tyrosine aminotransferase	O43708 P16930 P17735 P32754 Q93099	FAH GSTZ1 HGD HGO HPD MAAI PPD TAT
IRS activation	Growth factor receptor-bound protein 10 Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor Insulin	P01308 P06213 P35568 Q13322 Q9Y4H2	GRB10 GRBIR INS INSR IRS1 IRS2 KIAA0207
Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA)	Band 3 anion transport protein	P02730	AE1 DI EPB3 SLC4A1
Unblocking of NMDA receptors, glutamate binding and activation	Alpha-actinin-2 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Disks large homolog 1 Disks large homolog 2 Disks large homolog 3 Disks large homolog 4 Glutamate receptor 1 Glutamate receptor 2 Glutamate receptor 3 Glutamate receptor 4 Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2A Glutamate receptor ionotropic, NMDA 2B Glutamate receptor ionotropic, NMDA 2C Glutamate receptor ionotropic, NMDA 2D Leucine-rich repeat-containing protein 7 Neurofilament light polypeptide	O15399 P07196 P0DP23 P35609 P42261 P42262 P42263 P48058 P78352 Q05586 Q12879 Q12959 Q13224 Q13554 Q13555 Q13557 Q14957 Q15700 Q92796 Q96NW7 Q9UQM7	ACTN2 CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG DLG1 DLG2 DLG3 DLG4 GLUA1 GLUH1 GLUR1 GLUR2 GLUR3 GLUR4 GLURC GRIA1 GRIA2 GRIA3 GRIA4 GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D GluA2 GluA3 GluA4 GluN2D KIAA0968 KIAA1232 KIAA1365 LAP1 LRRC7 NEFL NF68 NFL NMDAR1 NMDAR2A NMDAR2B NMDAR2C NMDAR2D PSD95

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Summary

International Collaboration

Acknowledgements