GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **476 - 500** of **2090** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism	GlyTouCan ID
Formation of the posterior neural plate	Fibroblast growth factor 8 Homeobox protein GBX-2 Homeobox protein OTX2 POU domain, class 3, transcription factor 1 Protein Wnt-3a T-box transcription factor TBX6 Transcription factor SOX-1 Transcription factor SOX-2 Zinc finger E-box-binding homeobox 2 Zinc finger protein 521	O00570 O60315 O95947 P32243 P48431 P52951 P55075 P56704 Q03052 Q96K83	AIGF EHZF FGF8 GBX2 KIAA0569 LIP3 OCT6 OTF6 OTX2 POU3F1 SIP1 SOX1 SOX2 TBX6 WNT3A ZEB2 ZFHX1B ZFX1B ZNF521	Homo sapiens (human)
Pre-NOTCH Processing in Golgi	Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe Beta-1,3-N-acetylglucosaminyltransferase manic fringe Beta-1,3-N-acetylglucosaminyltransferase radical fringe Beta-1,4-galactosyltransferase 1 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 Furin Neurogenic locus notch homolog protein 1 Neurogenic locus notch homolog protein 2 Neurogenic locus notch homolog protein 3 Neurogenic locus notch homolog protein 4 Protein sel-1 homolog 1 Ras-related protein Rab-6A Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 Transmembrane emp24 domain-containing protein 2 Type 2 lactosamine alpha-2,3-sialyltransferase	O00587 O14983 P09958 P15291 P16615 P20340 P46531 Q04721 Q11203 Q11206 Q15363 Q8NES3 Q93084 Q99466 Q9UBV2 Q9UM47 Q9Y274 Q9Y644	ATP2A1 ATP2A2 ATP2A3 ATP2B B4GALT1 CGS23 FUR FURIN GGTB2 INT3 LFNG MFNG NANTA3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 PACE PCSK3 RAB6 RAB6A RFNG RNP24 SEL1L SIAT10 SIAT4C SIAT6 ST3GAL3 ST3GAL4 ST3GAL6 STZ TAN1 TMED2 TSA305	Homo sapiens (human)
Lectin pathway of complement activation	Collectin-10 Collectin-11 Ficolin-1 Ficolin-2 Ficolin-3 Mannan-binding lectin serine protease 1 Mannose-binding protein C	O00602 O75636 P11226 P48740 Q15485 Q9BWP8 Q9Y6Z7	CLL1 COLEC1 COLEC10 COLEC11 CRARF CRARF1 FCN1 FCN2 FCN3 FCNH FCNL FCNM HAKA1 MASP1 MBL MBL2 PRSS5	Homo sapiens (human)	G49108TO G57321FI
Ficolins bind to repetitive carbohydrate structures on the target cell surface	Ficolin-1 Ficolin-2 Ficolin-3 Mannan-binding lectin serine protease 1	O00602 O75636 P48740 Q15485	CRARF CRARF1 FCN1 FCN2 FCN3 FCNH FCNL FCNM HAKA1 MASP1 PRSS5	Homo sapiens (human)	G49108TO G57321FI
Class I peroxisomal membrane protein import	ATP-binding cassette sub-family D member 1 ATP-binding cassette sub-family D member 2 ATP-binding cassette sub-family D member 3 Acyl-CoA-binding domain-containing protein 5 Ganglioside-induced differentiation-associated protein 1 Mitochondrial fission 1 protein Outer mitochondrial transmembrane helix translocase Peroxisomal biogenesis factor 19 Peroxisomal biogenesis factor 3 Peroxisomal membrane protein 11B Peroxisomal membrane protein 2 Peroxisomal membrane protein 4 Peroxisomal membrane protein PEX13 Peroxisomal membrane protein PEX14 Peroxisomal membrane protein PEX16 Peroxisomal membrane protein PMP34 Peroxisome assembly protein 12 Peroxisome assembly protein 26 Peroxisome biogenesis factor 2	O00623 O43808 O75381 O96011 P28288 P28328 P33897 P40855 P56589 Q5T8D3 Q7Z412 Q8NBU5 Q8TB36 Q92968 Q9NR77 Q9UBJ2 Q9Y3D6 Q9Y5Y5 Q9Y6I8	ABCD1 ABCD2 ABCD3 ACBD5 ALD ALD1 ALDL1 ALDR ALDRP ATAD1 FIS1 GDAP1 HK33 KIAA1996 PAF1 PAF3 PEX11B PEX12 PEX13 PEX14 PEX16 PEX19 PEX2 PEX26 PEX3 PMP22 PMP24 PMP3 PMP34 PMP35 PMP70 PXF PXMP1 PXMP2 PXMP3 PXMP4 RNF72 SLC25A17 TTC11	Homo sapiens (human)
Digestion	Guanylate cyclase activator 2B Guanylin Guanylyl cyclase C Intestinal-type alkaline phosphatase Pirin	O00625 P09923 P25092 Q02747 Q16661	ALPI GUC2C GUCA2 GUCA2A GUCA2B GUCY2C PIR STAR	Homo sapiens (human)
Interleukin-4 and Interleukin-13 signaling	72 kDa type IV collagenase Amine oxidase [flavin-containing] A Annexin A1 Apoptosis regulator Bcl-2 B-cell lymphoma 6 protein Baculoviral IAP repeat-containing protein 5 Basic leucine zipper transcriptional factor ATF-like Bcl-2-like protein 1 C-C motif chemokine 22 C-C motif chemokine 2 CCAAT/enhancer-binding protein delta Cellular tumor antigen p53 Coagulation factor XIII A chain Collagen alpha-2(I) chain Cyclin-dependent kinase inhibitor 1 Cytokine receptor common subunit gamma Delta-type opioid receptor Endoplasmin Eotaxin Fascin Fibroblast growth factor 2 Fibronectin Forkhead box protein O1 Forkhead box protein O3 G1/S-specific cyclin-D1 Heat shock cognate 71 kDa protein Heat shock protein HSP 90-alpha Heme oxygenase 1 Hepatocyte growth factor Homeobox protein NANOG Hypoxia-inducible factor 1-alpha Immunoglobulin heavy constant epsilon Immunoglobulin heavy constant gamma 1 Immunoglobulin heavy constant gamma 4 Induced myeloid leukemia cell differentiation protein Mcl-1 Integrin alpha-M Integrin alpha-X Integrin beta-1 Integrin beta-2 Intercellular adhesion molecule 1 Interferon regulatory factor 4 Interleukin-1 alpha Interleukin-1 beta Interleukin-10 Interleukin-12 subunit alpha Interleukin-12 subunit beta Interleukin-13 receptor subunit alpha-1 Interleukin-13 receptor subunit alpha-2 Interleukin-13 Interleukin-17A Interleukin-17F Interleukin-18 Interleukin-23 receptor Interleukin-23 subunit alpha Interleukin-4 receptor subunit alpha Interleukin-4 Interleukin-6 receptor subunit alpha Interleukin-6 Interleukin-8 Interstitial collagenase Laminin subunit alpha-5 Leukemia inhibitory factor Lipopolysaccharide-binding protein Low affinity immunoglobulin epsilon Fc receptor Matrix metalloproteinase-9 Metalloproteinase inhibitor 1 Mu-type opioid receptor Mucin-1 Myc proto-oncogene protein Necdin Neutrophil gelatinase-associated lipocalin Nitric oxide synthase, inducible Non-receptor tyrosine-protein kinase TYK2 Nuclear receptor ROR-alpha Nuclear receptor ROR-gamma Oncostatin-M POU domain, class 2, transcription factor 1 Phosphatidylinositol 3-kinase regulatory subunit alpha Platelet glycoprotein 4 Polyunsaturated fatty acid 5-lipoxygenase Polyunsaturated fatty acid lipoxygenase ALOX15 Pro-opiomelanocortin Prostaglandin G/H synthase 2 Protein c-Fos RAC-alpha serine/threonine-protein kinase Rho-related GTP-binding protein RhoU Serine/threonine-protein kinase pim-1 Serum amyloid A-1 protein Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 6 Sphingosine 1-phosphate receptor 1 Stromelysin-1 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Suppressor of cytokine signaling 5 Trans-acting T-cell-specific transcription factor GATA-3 Transcription factor JunB Transcription factor SOX-2 Transforming growth factor beta-1 proprotein Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor receptor superfamily member 1B Tumor necrosis factor Twist-related protein 1 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase JAK3 Vascular cell adhesion protein 1 Vascular endothelial growth factor A, long form Vimentin Zinc finger E-box-binding homeobox 1	O00626 O14543 O15230 O15392 O15524 O43524 O60674 O75159 P00488 P01033 P01100 P01106 P01137 P01189 P01375 P01583 P01584 P01854 P01857 P01861 P02751 P03956 P04083 P04637 P05107 P05112 P05231 P05362 P05556 P06734 P07900 P08123 P08253 P08254 P08670 P08887 P09038 P09601 P09917 P0DJI8 P10145 P10415 P11142 P11215 P11309 P13500 P13725 P14210 P14625 P14780 P14859 P15018 P15692 P15941 P16050 P16671 P17275 P18428 P19320 P20333 P20702 P21397 P21453 P22301 P23458 P23771 P24385 P24394 P27986 P29459 P29460 P29597 P31749 P31785 P35225 P35228 P35354 P35372 P35398 P37275 P38936 P40763 P41143 P41182 P42224 P42226 P48023 P48431 P49716 P51449 P51671 P52333 P78552 P80188 Q07817 Q07820 Q12778 Q14116 Q14627 Q15306 Q15672 Q16520 Q16552 Q16658 Q16665 Q5VWK5 Q7L0Q8 Q96PD4 Q99608 Q9H9S0 Q9NPF7	AKT1 ALOX15 ALOX5 ANX1 ANXA1 API4 APRF APT1LG1 AREB6 ARHU BATF BCL1 BCL2 BCL2L BCL2L1 BCL2L3 BCL5 BCL6 BCLX BHLHA38 BHLHE39 BHLHE78 BIRC5 CAP20 CCL11 CCL2 CCL22 CCND1 CD11B CD11C CD18 CD23A CD36 CD95L CDC42L1 CDKN1 CDKN1A CEBPD CHEDG1 CIP1 CIS3 CIS6 CISH5 CISH6 CLEC4J CLG CLG4A CLG4B CLGI COL1A2 COX2 CR3A CTLA8 CXCL8 EDG1 F13A F13A1 FAN1 FASL FASLG FCE2 FCER2 FGF2 FGFB FKHR FKHRL1 FN FN1 FNRB FOS FOXO1 FOXO1A FOXO3 FOXO3A FSCN1 G0S7 G28K GATA3 GP3B GP4 GRB1 GRP94 HGF HIF1A HILDA HMOX1 HNL HO HO1 HPTA HSC70 HSN HSP73 HSP90A HSP90AA1 HSP90B1 HSPA10 HSPA8 HSPC1 HSPC4 HSPCA IAP4 ICAM1 IFNB2 IGEBF IGHE IGHG1 IGHG4 IGIF IL10 IL12A IL12B IL13 IL13R IL13RA IL13RA1 IL13RA2 IL17 IL17A IL17F IL18 IL1A IL1B IL1F1 IL1F2 IL1F4 IL23A IL23R IL2RG IL4 IL4R IL4RA IL6 IL6R IL8 IRF4 ITGAM ITGAX ITGB1 ITGB2 JAK1 JAK1A JAK1B JAK2 JAK3 JUNB KIAA0533 KIAA0671 KIAA1907 LAMA5 LAZ3 LBP LCN2 LIF LOG15 LOG5 LPC1 MAOA MCL1 MCP1 MDA6 MDC MDF2 MFI7 MMP1 MMP2 MMP3 MMP9 MOP1 MOR1 MSK12 MUC1 MUM1 MYC NANOG NC30 NDN NGAL NKSF1 NKSF2 NOS2 NOS2A NR1F1 NR1F3 OCT1 OPRD OPRD1 OPRM1 OSM OTF1 P53 PASD8 PIC1 PIK3R1 PIM1 PKB POMC POU2F1 PRAD1 PTGS2 PUM RAC RHOU RORA RORC RORG RZRA RZRG S1PR1 SAA1 SCYA11 SCYA2 SCYA22 SDI1 SGRF SNL SOCS1 SOCS3 SOCS5 SOX2 SSI1 SSI3 STAT1 STAT3 STAT6 STMY1 TCF8 TGFB TGFB1 TIMP TIMP1 TIP3 TNF TNFA TNFBR TNFR2 TNFRSF1B TNFSF2 TNFSF6 TP53 TRA1 TWIST TWIST1 TYK2 VCAM1 VEGF VEGFA VIM WAF1 WRCH1 ZBTB27 ZEB1 ZNF51	Homo sapiens (human)
Interleukin-10 signaling	C-C chemokine receptor type 1 C-C chemokine receptor type 2 C-C chemokine receptor type 5 C-C motif chemokine 19 C-C motif chemokine 20 C-C motif chemokine 22 C-C motif chemokine 2 C-C motif chemokine 3-like 1 C-C motif chemokine 3 C-C motif chemokine 4 C-C motif chemokine 5 C-X-C motif chemokine 10 C-X-C motif chemokine 2 Granulocyte colony-stimulating factor Granulocyte-macrophage colony-stimulating factor Growth-regulated alpha protein Intercellular adhesion molecule 1 Interleukin-1 alpha Interleukin-1 beta Interleukin-1 receptor antagonist protein Interleukin-1 receptor type 1 Interleukin-1 receptor type 2 Interleukin-10 receptor subunit alpha Interleukin-10 receptor subunit beta Interleukin-10 Interleukin-12 subunit alpha Interleukin-12 subunit beta Interleukin-18 Interleukin-6 Interleukin-8 Leukemia inhibitory factor Low affinity immunoglobulin epsilon Fc receptor Macrophage colony-stimulating factor 1 Metalloproteinase inhibitor 1 Non-receptor tyrosine-protein kinase TYK2 Platelet-activating factor receptor Prostaglandin G/H synthase 2 Signal transducer and activator of transcription 3 T-lymphocyte activation antigen CD80 T-lymphocyte activation antigen CD86 Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor superfamily member 1B Tumor necrosis factor Tyrosine-protein kinase JAK1 fMet-Leu-Phe receptor	O00626 P01033 P01375 P01583 P01584 P02778 P04141 P05231 P05362 P06734 P09341 P09603 P09919 P10145 P10147 P13236 P13500 P13501 P14778 P15018 P16619 P18510 P19438 P19875 P20333 P21462 P22301 P23458 P25105 P27930 P29459 P29460 P29597 P32246 P33681 P35354 P40763 P41597 P42081 P51681 P78556 Q08334 Q13651 Q14116 Q99731	APRF C17orf33 CCL19 CCL2 CCL20 CCL22 CCL3 CCL3L1 CCL3L3 CCL4 CCL5 CCR1 CCR2 CCR5 CD23A CD28LG CD28LG1 CD28LG2 CD80 CD86 CLEC4J CLGI CMKBR1 CMKBR2 CMKBR5 CMKR1 COX2 CRFB4 CSF1 CSF2 CSF3 CXCL1 CXCL10 CXCL2 CXCL8 D17S136E D17S1718 D21S58 D21S66 ELC FCE2 FCER2 FPR1 G0S19-1 G0S19-2 GCSF GMCSF GRO GRO1 GRO2 GROA GROB HILDA ICAM1 IFNB2 IGEBF IGIF IL10 IL10R IL10RA IL10RB IL12A IL12B IL18 IL1A IL1B IL1F1 IL1F2 IL1F3 IL1F4 IL1R IL1R1 IL1R2 IL1RA IL1RB IL1RN IL1RT1 IL6 IL8 INP10 JAK1 JAK1A JAK1B LAB7 LAG1 LARC LIF MCP1 MDC MGSA MIP1A MIP1B MIP2A MIP3A MIP3B NKSF1 NKSF2 PAFR PTAFR PTGS2 SCYA19 SCYA2 SCYA20 SCYA22 SCYA3 SCYA3L1 SCYA4 SCYA5 SCYAR1 SCYB1 SCYB10 SCYB2 STAT3 TIMP TIMP1 TNF TNFA TNFAR TNFBR TNFR1 TNFR2 TNFRSF1A TNFRSF1B TNFSF2 TYK2	Homo sapiens (human)
Myogenesis	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 C-Jun-amino-terminal kinase-interacting protein 4 Cadherin-15 Cadherin-2 Cadherin-4 Catenin alpha-1 Catenin alpha-2 Catenin beta-1 Cell adhesion molecule-related/down-regulated by oncogenes Cell division control protein 42 homolog Dual specificity mitogen-activated protein kinase kinase 6 Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 12 Mitogen-activated protein kinase 14 Myoblast determination protein 1 Myocyte-specific enhancer factor 2A Myocyte-specific enhancer factor 2B Myocyte-specific enhancer factor 2C Myocyte-specific enhancer factor 2D Myogenic factor 5 Myogenic factor 6 Myogenin Neogenin Netrin-3 Transcription factor 12 Transcription factor 4 Transcription factor E2-alpha Tyrosine-protein kinase ABL1	O00634 O60271 P00519 P13349 P15172 P15173 P15884 P15923 P19022 P23409 P26232 P35221 P35222 P52564 P53778 P55283 P55291 P60953 Q02078 Q02080 Q06413 Q12982 Q14814 Q15759 Q16539 Q4KMG0 Q92859 Q99081	ABL ABL1 BHLHB19 BHLHB20 BHLHB21 BHLHC1 BHLHC2 BHLHC3 BHLHC4 BNIP2 CAPR CDC42 CDH14 CDH15 CDH2 CDH3 CDH4 CDHN CDO CDON CSBP CSBP1 CSBP2 CSPB1 CTNNA1 CTNNA2 CTNNB CTNNB1 E2A ERK6 HEB HSS HTF4 IGDCC2 ITF1 ITF2 JTK7 KIAA0516 MAP2K6 MAPK11 MAPK12 MAPK14 MAPK8IP4 MEF2 MEF2A MEF2B MEF2C MEF2D MEK6 MKK6 MRF4 MXI2 MYF3 MYF4 MYF5 MYF6 MYOD MYOD1 MYOG NCAD NEO1 NGN NIP2 NTN2L NTN3 PRKM11 PRKMK6 SAPK2 SAPK2A SAPK2B SAPK3 SEF2 SKK3 SPAG9 SYD1 TCF12 TCF3 TCF4 XMEF2	Homo sapiens (human)
Interferon gamma signaling	2'-5'-oligoadenylate synthase 1 2'-5'-oligoadenylate synthase 2 2'-5'-oligoadenylate synthase 3 2'-5'-oligoadenylate synthase-like protein Beta-2-microglobulin CD44 antigen Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma E3 ubiquitin-protein ligase Midline-1 E3 ubiquitin-protein ligase TRIM17 E3 ubiquitin-protein ligase TRIM21 E3 ubiquitin-protein ligase TRIM22 E3 ubiquitin-protein ligase TRIM31 E3 ubiquitin-protein ligase TRIM34 E3 ubiquitin-protein ligase TRIM35 E3 ubiquitin-protein ligase TRIM38 E3 ubiquitin-protein ligase TRIM45 E3 ubiquitin-protein ligase TRIM48 E3 ubiquitin-protein ligase TRIM62 E3 ubiquitin-protein ligase TRIM68 E3 ubiquitin-protein ligase TRIM8 E3 ubiquitin/ISG15 ligase TRIM25 Gamma-interferon-inducible lysosomal thiol reductase Guanylate-binding protein 1 Guanylate-binding protein 2 Guanylate-binding protein 3 Guanylate-binding protein 4 Guanylate-binding protein 5 Guanylate-binding protein 6 Guanylate-binding protein 7 HLA class I histocompatibility antigen, A alpha chain HLA class I histocompatibility antigen, B alpha chain HLA class I histocompatibility antigen, C alpha chain HLA class I histocompatibility antigen, alpha chain E HLA class I histocompatibility antigen, alpha chain F HLA class I histocompatibility antigen, alpha chain G HLA class II histocompatibility antigen, DP alpha 1 chain HLA class II histocompatibility antigen, DP beta 1 chain HLA class II histocompatibility antigen, DQ alpha 1 chain HLA class II histocompatibility antigen, DQ alpha 2 chain HLA class II histocompatibility antigen, DQ beta 1 chain HLA class II histocompatibility antigen, DQ beta 2 chain HLA class II histocompatibility antigen, DR alpha chain HLA class II histocompatibility antigen, DR beta 3 chain HLA class II histocompatibility antigen, DR beta 4 chain HLA class II histocompatibility antigen, DR beta 5 chain HLA class II histocompatibility antigen, DRB1 beta chain High affinity immunoglobulin gamma Fc receptor I Intercellular adhesion molecule 1 Interferon gamma receptor 1 Interferon gamma receptor 2 Interferon gamma Interferon regulatory factor 1 Interferon regulatory factor 2 Interferon regulatory factor 3 Interferon regulatory factor 4 Interferon regulatory factor 5 Interferon regulatory factor 6 Interferon regulatory factor 7 Interferon regulatory factor 8 Interferon regulatory factor 9 MHC class II transactivator Metallothionein-2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mothers against decapentaplegic homolog 7 Neural cell adhesion molecule 1 Nuclear autoantigen Sp-100 Platelet-activating factor receptor Protein PML Protein kinase C delta type Putative HLA class I histocompatibility antigen, alpha chain H Putative high affinity immunoglobulin gamma Fc receptor IB Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tripartite motif-containing protein 10 Tripartite motif-containing protein 14 Tripartite motif-containing protein 26 Tripartite motif-containing protein 29 Tripartite motif-containing protein 2 Tripartite motif-containing protein 3 Tripartite motif-containing protein 46 Tripartite motif-containing protein 5 Tripartite motif-containing protein 6 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein phosphatase non-receptor type 6 Vascular cell adhesion protein 1 Y-box-binding protein 1	O00635 O14543 O14896 O15105 O15344 O15524 O60674 O75382 P00973 P01579 P01889 P01893 P01903 P01906 P01909 P01911 P01920 P02795 P04439 P04440 P05362 P05538 P10321 P10914 P12314 P13284 P13591 P13747 P13762 P14316 P15260 P16070 P17693 P19320 P19474 P20036 P23458 P23497 P25105 P27361 P28482 P29350 P29590 P29728 P30511 P32455 P32456 P33076 P38484 P61769 P67809 P79483 Q00978 Q02556 Q05655 Q12899 Q13554 Q13555 Q13557 Q13568 Q14134 Q14142 Q14258 Q14653 Q15306 Q15646 Q30154 Q6AZZ1 Q6ZN66 Q7Z4K8 Q8IWZ4 Q8IYM9 Q8N8V2 Q92637 Q92985 Q96PP8 Q96PP9 Q9BVG3 Q9BYJ4 Q9BZR9 Q9BZY9 Q9C030 Q9C035 Q9C040 Q9H0R5 Q9H8W5 Q9UDY6 Q9UPQ4 Q9UQM7 Q9Y577 Q9Y6K5	ATDC B2M BERP C6orf13 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CD44 CES1 CIITA CIS3 EFP ERK1 ERK2 FCG1 FCGR1 FCGR1A FCGR1B FCGR1BP FXY GBP1 GBP2 GBP3 GBP4 GBP4L GBP5 GBP6 GBP7 GC109 GERP GILT HCP HLA-5.4 HLA-6.0 HLA-6.2 HLA-A HLA-B HLA-C HLA-DP1A HLA-DP1B HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB HLA-DQB1 HLA-DQB2 HLA-DRA HLA-DRA1 HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 HLA-DXA HLA-DXB HLA-E HLA-F HLA-G HLA-H HLAA HLAB HLAC HLAE HLAF HLAG HLAH HLASB HLS5 ICAM1 ICSBP1 IFI30 IFNG IFNGR1 IFNGR2 IFNGT1 IFP1 IGFR1 IGFRB IP30 IRF1 IRF2 IRF3 IRF4 IRF5 IRF6 IRF7 IRF8 IRF9 ISGF3G JAK1 JAK1A JAK1B JAK2 KIAA0129 KIAA0517 KIAA0968 KIAA1098 LHR MADH7 MADH8 MAPK1 MAPK3 MDU2 MDU3 MHC2TA MIC4 MID1 MT2 MT2A MUM1 MYL NCAM NCAM1 NSEP1 OAS1 OAS2 OAS3 OASL OIAS PAFR PKCD PML PP8675 PRKCD PRKM1 PRKM2 PRKM3 PTAFR PTP1C PTPN6 RBCC RFB30 RNF RNF101 RNF137 RNF147 RNF15 RNF16 RNF21 RNF22 RNF27 RNF59 RNF71 RNF81 RNF86 RNF88 RNF89 RNF9 RNF94 RNF95 RNF97 RNF99 RO52 RORET SMAD7 SOCS1 SOCS3 SP100 SS56 SSA1 SSI1 SSI3 STAF50 TERF TIP3 TRIFIC TRIM10 TRIM14 TRIM17 TRIM18 TRIM19 TRIM2 TRIM21 TRIM22 TRIM25 TRIM26 TRIM29 TRIM3 TRIM31 TRIM34 TRIM35 TRIM38 TRIM45 TRIM46 TRIM48 TRIM5 TRIM6 TRIM62 TRIM68 TRIM8 TRIP14 VCAM1 XPRF YB1 YBX1 ZNF147 ZNF173	Homo sapiens (human)
RNA Polymerase III Transcription Termination	DNA-directed RNA polymerase III subunit RPC10 DNA-directed RNA polymerase III subunit RPC1 DNA-directed RNA polymerase III subunit RPC2 DNA-directed RNA polymerase III subunit RPC3 DNA-directed RNA polymerase III subunit RPC4 DNA-directed RNA polymerase III subunit RPC5 DNA-directed RNA polymerase III subunit RPC6 DNA-directed RNA polymerase III subunit RPC7-like DNA-directed RNA polymerase III subunit RPC7 DNA-directed RNA polymerase III subunit RPC8 DNA-directed RNA polymerase III subunit RPC9 DNA-directed RNA polymerases I and III subunit RPAC1 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Lupus La protein Nuclear factor 1 A-type Nuclear factor 1 B-type Nuclear factor 1 C-type Nuclear factor 1 X-type Protein POLR1D, isoform 2	O00712 O14802 O15160 O15318 O75575 P05423 P05455 P08651 P0DPB5 P19388 P52434 P53803 P61218 P62875 Q12857 Q14938 Q9BT43 Q9BUI4 Q9H1D9 Q9NVU0 Q9NW08 Q9Y2Y1 Q9Y535	BN51 BN51T CRCP KIAA1439 KIAA1452 KIAA1665 NFI NFIA NFIB NFIC NFIX POLR1C POLR1D POLR1E POLR2E POLR2F POLR2H POLR2K POLR2L POLR3A POLR3B POLR3C POLR3D POLR3E POLR3F POLR3G POLR3GL POLR3H POLR3K POLRF RPC11 RPC8 SSB	Homo sapiens (human)
Oncogene Induced Senescence	Cellular tumor antigen p53 Cyclin-dependent kinase 4 inhibitor B Cyclin-dependent kinase 4 inhibitor C Cyclin-dependent kinase 4 inhibitor D Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 Cyclin-dependent kinase inhibitor 2A DNA-binding protein inhibitor ID-1 E3 ubiquitin-protein ligase Mdm2 ETS domain-containing transcription factor ERF Helicase MOV-10 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Polyubiquitin-B Polyubiquitin-C Protein C-ets-1 Protein C-ets-2 Protein Mdm4 Protein argonaute-1 Protein argonaute-3 Protein argonaute-4 Retinoblastoma-associated protein Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor E2F2 Transcription factor E2F3 Transcription factor Sp1 Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein Tumor suppressor ARF Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00716 O15151 P04637 P06400 P08047 P0CG47 P0CG48 P11802 P14921 P15036 P27361 P28482 P41134 P42771 P42772 P42773 P50548 P55273 P62979 P62987 Q00534 Q00987 Q01094 Q14186 Q14188 Q14209 Q8N726 Q8NDV7 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9UL18 Q9UPQ9	AGO1 AGO3 AGO4 BHLHB24 CAGH26 CDK4 CDK6 CDKN2 CDKN2A CDKN2B CDKN2C CDKN2D CDKN6 DP1 DP2 E2F1 E2F2 E2F3 EIF2C1 EIF2C3 EIF2C4 ERF ERK1 ERK2 ETS1 ETS2 EWSR2 ID ID1 KIAA0075 KIAA1093 KIAA1460 KIAA1567 KIAA1582 KIAA1631 MAPK1 MAPK3 MDM2 MDM4 MDMX MLM MOV10 MTS1 MTS2 P53 PRKM1 PRKM2 PRKM3 RB1 RBBP3 RPS27A SP1 TFDP1 TFDP2 TNRC6 TNRC6A TNRC6B TNRC6C TP53 TSFP1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Cyclin D associated events in G1	CDK-activating kinase assembly factor MAT1 Cullin-1 Cyclin-H Cyclin-dependent kinase 2 Cyclin-dependent kinase 4 inhibitor B Cyclin-dependent kinase 4 inhibitor C Cyclin-dependent kinase 4 inhibitor D Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 Cyclin-dependent kinase 7 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B Cyclin-dependent kinase inhibitor 1C Cyclin-dependent kinase inhibitor 2A Cyclin-dependent kinases regulatory subunit 1 G1/S-specific cyclin-D1 G1/S-specific cyclin-D2 G1/S-specific cyclin-D3 G1/S-specific cyclin-E1 G1/S-specific cyclin-E2 Polyubiquitin-B Polyubiquitin-C Protein-tyrosine kinase 6 Retinoblastoma-associated protein Retinoblastoma-like protein 1 Retinoblastoma-like protein 2 S-phase kinase-associated protein 1 S-phase kinase-associated protein 2 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor E2F2 Transcription factor E2F3 Transcription factor E2F4 Transcription factor E2F5 Tyrosine-protein kinase ABL1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00716 O60674 O96020 P00519 P06400 P07948 P0CG47 P0CG48 P11802 P24385 P24864 P24941 P28749 P30153 P30154 P30279 P30281 P38936 P42771 P42772 P42773 P46527 P49918 P50613 P51946 P51948 P55273 P61024 P62714 P62979 P62987 P63151 P63208 P67775 Q00534 Q01094 Q08999 Q13309 Q13616 Q13882 Q14186 Q14188 Q14209 Q15329 Q16254 Q9Y5P8	ABL ABL1 BCL1 BRK CAK CAK1 CAP20 CAP35 CCND1 CCND2 CCND3 CCNE CCNE1 CCNE2 CCNH CDK2 CDK4 CDK6 CDK7 CDKN1 CDKN1A CDKN1B CDKN1C CDKN2 CDKN2A CDKN2B CDKN2C CDKN2D CDKN6 CDKN7 CIP1 CKS1 CKS1B CUL1 DP1 DP2 E2F1 E2F2 E2F3 E2F4 E2F5 EMC19 FBXL1 JAK2 JTK7 JTK8 KIAA0075 KIP1 KIP2 LYN MAT1 MDA6 MNAT1 MO15 MTS1 MTS2 OCP2 PIC1 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R2A PPP2R3B PPP2R3L PRAD1 PTK6 RB1 RB2 RBBP3 RBL1 RBL2 RNF66 RPS27A SDI1 SKP1 SKP1A SKP2 STK1 TCEB1L TFDP1 TFDP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WAF1 p27	Homo sapiens (human)
Pre-NOTCH Transcription and Translation	CREB-binding protein Cellular tumor antigen p53 ETS-related transcription factor Elf-3 G1/S-specific cyclin-D1 Helicase MOV-10 Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Histone acetyltransferase KAT2A Histone acetyltransferase KAT2B Histone acetyltransferase p300 Mastermind-like domain-containing protein 1 Mastermind-like protein 1 Mastermind-like protein 2 Mastermind-like protein 3 NAD-dependent protein deacylase sirtuin-6 Neurogenic locus notch homolog protein 1 Neurogenic locus notch homolog protein 2 Neurogenic locus notch homolog protein 3 Neurogenic locus notch homolog protein 4 Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Protein kinase C iota type Recombining binding protein suppressor of hairless Runt-related transcription factor 1 SNW domain-containing protein 1 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor E2F3 Transcription factor Jun Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein	O00716 O60814 P04637 P04908 P05412 P06899 P0C5Y9 P16104 P20671 P23527 P24385 P33778 P41743 P46531 P57053 P58876 P62805 P62807 P68431 P78545 P84243 Q01094 Q01196 Q04721 Q06330 Q09472 Q13495 Q13573 Q14186 Q14188 Q16777 Q16778 Q6FI13 Q71DI3 Q71UI9 Q8IZL2 Q8N257 Q8N6T7 Q8NDV7 Q92585 Q92793 Q92830 Q92831 Q93077 Q93079 Q96A08 Q96JK9 Q99466 Q99877 Q99878 Q99879 Q99880 Q9BTM1 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9UKV8 Q9UL18 Q9UM47 Q9UPQ9	AGO1 AGO2 AGO3 AGO4 AML1 BCL1 CAGH26 CBFA2 CBP CCND1 CG1 CREBBP CXorf6 DP1 DP2 DXS1179E E2F1 E2F3 EIF2C1 EIF2C2 EIF2C3 EIF2C4 ELF3 EP300 ERT ESX GCN5 GCN5L2 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 IGKJRB IGKJRB1 INT3 JEN JUN KAT2A KAT2B KIAA0075 KIAA0200 KIAA1093 KIAA1460 KIAA1567 KIAA1582 KIAA1631 KIAA1816 KIAA1819 MAML1 MAML2 MAML3 MAMLD1 MOV10 NOTCH1 NOTCH2 NOTCH3 NOTCH4 P300 P53 PCAF PRAD1 PRKCI RBBP3 RBPJ RBPJK RBPSUH RUNX1 SIR2L6 SIRT6 SKIIP SKIP SNW1 TAN1 TFDP1 TFDP2 TNRC6 TNRC6A TNRC6B TNRC6C TP53 TSH2B	Homo sapiens (human)
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)	Cyclin-dependent kinase 2 Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B Cyclin-dependent kinase inhibitor 1C G1/S-specific cyclin-D1 G1/S-specific cyclin-D2 G1/S-specific cyclin-D3 G1/S-specific cyclin-E1 G1/S-specific cyclin-E2 Retinoblastoma-associated protein Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor E2F2 Transcription factor E2F3	O00716 O96020 P06400 P11802 P24385 P24864 P24941 P30279 P30281 P38936 P46527 P49918 Q00534 Q01094 Q14186 Q14188 Q14209	BCL1 CAP20 CCND1 CCND2 CCND3 CCNE CCNE1 CCNE2 CDK2 CDK4 CDK6 CDKN1 CDKN1A CDKN1B CDKN1C CDKN2 CDKN6 CIP1 DP1 DP2 E2F1 E2F2 E2F3 KIAA0075 KIP1 KIP2 MDA6 PIC1 PRAD1 RB1 RBBP3 SDI1 TFDP1 TFDP2 WAF1 p27	Homo sapiens (human)
G2 Phase	Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 Transcription factor E2F1 Transcription factor E2F3	O00716 P20248 P24941 P78396 Q01094	CCN1 CCNA CCNA1 CCNA2 CDK2 CDKN2 E2F1 E2F3 KIAA0075 RBBP3	Homo sapiens (human)
COPII-mediated vesicle transport	Alpha-1-antitrypsin Alpha-soluble NSF attachment protein Amphiregulin BET1 homolog Beta-soluble NSF attachment protein CD59 glycoprotein Casein kinase I isoform delta Cathepsin Z Coagulation factor V Coagulation factor VIII Collagen alpha-1(VII) chain Dipeptidyl peptidase 1 Folate receptor alpha Gamma-soluble NSF attachment protein General vesicular transport factor p115 Glutamate receptor 1 Golgi SNAP receptor complex member 2 Golgi reassembly-stacking protein 1 Golgin subfamily A member 2 Guanine nucleotide-exchange factor SEC12 Multiple coagulation factor deficiency protein 2 Protein ERGIC-53-like Protein ERGIC-53 Protein SEC13 homolog Protein TFG Protein cornichon homolog 1 Protein cornichon homolog 2 Protein cornichon homolog 3 Protein transport protein Sec16A Protein transport protein Sec16B Protein transport protein Sec23A Protein transport protein Sec24A Protein transport protein Sec24B Protein transport protein Sec24C Protein transport protein Sec24D Protein transport protein Sec31A Protransforming growth factor alpha Ras-related protein Rab-1A Ras-related protein Rab-1B SEC23-interacting protein Sec1 family domain-containing protein 1 Serine/threonine-protein phosphatase 6 catalytic subunit Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A Serine/threonine-protein phosphatase 6 regulatory subunit 1 Serine/threonine-protein phosphatase 6 regulatory subunit 3 Small COPII coat GTPase SAR1B Synaptobrevin homolog YKT6 Syntaxin-17 Syntaxin-5 TBC1 domain family member 20 Trafficking protein particle complex subunit 10 Trafficking protein particle complex subunit 1 Trafficking protein particle complex subunit 2-like protein Trafficking protein particle complex subunit 2 Trafficking protein particle complex subunit 3 Trafficking protein particle complex subunit 4 Trafficking protein particle complex subunit 5 Trafficking protein particle complex subunit 6A Trafficking protein particle complex subunit 6B Trafficking protein particle complex subunit 9 Transmembrane emp24 domain-containing protein 10 Transmembrane emp24 domain-containing protein 2 VIP36-like protein Vesicle-fusing ATPase Vesicle-trafficking protein SEC22a Vesicle-trafficking protein SEC22b Vesicle-trafficking protein SEC22c Vesicular integral-membrane protein VIP36	O00743 O14653 O15027 O15084 O15155 O15498 O43617 O60763 O75396 O75865 O94855 O94979 O95406 O95486 O95487 P00451 P01009 P01135 P0DI81 P12259 P13987 P15328 P15514 P42261 P46459 P48553 P48730 P49257 P49755 P53634 P53992 P54920 P55735 P56962 P62820 Q02388 Q08379 Q12907 Q13190 Q15363 Q15436 Q5H9R7 Q6PI25 Q86SZ2 Q8IUR0 Q8NI22 Q8TBE1 Q8WVM8 Q92734 Q96BZ9 Q96IW7 Q96JE7 Q96Q05 Q99747 Q9BQQ3 Q9BRL7 Q9H0U4 Q9H0V9 Q9H115 Q9HAT1 Q9HCU5 Q9UBR2 Q9UL33 Q9UPN7 Q9Y296 Q9Y5R8 Q9Y6B6 Q9Y6Y8	AAT ANKRD28 AREG AREGB BET1 BET3 BET5 C11orf23 C14orf163 C20orf140 C5orf8 CD59 CNIH CNIH1 CNIH2 CNIH3 CNIL COL7A1 CPPI CSNK1D CTSC CTSZ D3S1231E EHOC1 ERGIC53 ERGL F5 F5F8D F8 F8C FOLR FOLR1 GLUA1 GLUH1 GLUR1 GOLGA2 GOLPH5 GORASP1 GOSR2 GRASP65 GRIA1 GS27 HCKID KIAA0079 KIAA0310 KIAA0379 KIAA0755 KIAA0905 KIAA0917 KIAA1115 KIAA1558 KIAA1882 KIAA1928 LMAN1 LMAN1L LMAN2 LMAN2L LZTR2 MCFD2 MIC11 MIN1 MIN2 MIN3 MSK21 MUM2 NAPA NAPB NAPG NIBP NSF PI PP6R1 PP6R3 PPP6 PPP6C PPP6R1 PPP6R3 PREB RAB1 RAB1A RAB1B RGPR RNP24 SAPL SAPS1 SAPS3 SAR1B SARA2 SARB SBDN SCFD1 SDGF SDNSF SEC12 SEC13 SEC13A SEC13L1 SEC13R SEC16 SEC16A SEC16B SEC16L SEC16S SEC22A SEC22B SEC22C SEC22L1 SEC22L2 SEC22L3 SEC23A SEC23IP SEC24A SEC24B SEC24C SEC24D SEC31A SEC31L1 SEDL SERPINA1 SNAPA SNAPB SNAPG STX17 STX5 STX5A STXBP1L2 TBC1D20 TFG TGFA TMED10 TMED2 TMEM1 TMP21 TRAPPC1 TRAPPC10 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC4 TRAPPC5 TRAPPC6A TRAPPC6B TRAPPC9 USO1 VDP VIPL YKT6	Homo sapiens (human)
Telomere Extension By Telomerase	ATP-dependent DNA helicase PIF1 Adrenocortical dysplasia protein homolog Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 H/ACA ribonucleoprotein complex subunit 1 H/ACA ribonucleoprotein complex subunit 2 H/ACA ribonucleoprotein complex subunit 3 H/ACA ribonucleoprotein complex subunit DKC1 Protection of telomeres protein 1 Protein SHQ1 homolog Regulator of telomere elongation helicase 1 RuvB-like 1 RuvB-like 2 Serine/threonine-protein phosphatase 6 catalytic subunit Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A Serine/threonine-protein phosphatase 6 regulatory subunit 3 TERF1-interacting nuclear factor 2 Telomerase Cajal body protein 1 Telomerase reverse transcriptase Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2	O00743 O14746 O15084 O60832 P20248 P24941 P54274 P78396 Q15554 Q5H9R7 Q6PI26 Q96AP0 Q9BSI4 Q9BUR4 Q9H611 Q9NPE3 Q9NUX5 Q9NX24 Q9NY12 Q9NYB0 Q9NZ71 Q9Y230 Q9Y265	ACD ANKRD28 C11orf23 C15orf20 C20orf41 CCN1 CCNA CCNA1 CCNA2 CDK2 CDKN2 DKC1 DRIP5 EST2 GAR1 INO80H INO80J KIAA0379 KIAA1088 KIAA1558 NHL NHP2 NMP238 NOLA1 NOLA2 NOLA3 NOLA4 NOP10 PIF1 PIN2 PIP1 POT1 PP6R3 PPP6 PPP6C PPP6R3 PTOP RAP1 RTEL1 RUVBL1 RUVBL2 SAPL SAPS3 SHQ1 TCAB1 TCS1 TERF1 TERF2 TERF2IP TERT TIN2 TINF2 TINT1 TIP48 TIP49 TIP49A TIP49B TPP1 TRBF1 TRBF2 TRF TRF1 TRF2 TRT WDR79 WRAP53	Homo sapiens (human)
WNT ligand biogenesis and trafficking	Protein Wnt-10a Protein Wnt-10b Protein Wnt-11 Protein Wnt-16 Protein Wnt-2 Protein Wnt-2b Protein Wnt-3a Protein Wnt-4 Protein Wnt-5a Protein Wnt-5b Protein Wnt-6 Protein Wnt-7a Protein Wnt-7b Protein Wnt-8a Protein Wnt-8b Protein Wnt-9a Protein Wnt-9b Protein wntless homolog Protein-serine O-palmitoleoyltransferase porcupine Proto-oncogene Wnt-1 Proto-oncogene Wnt-3 Sorting nexin-3 Transmembrane emp24 domain-containing protein 5 Vacuolar protein sorting-associated protein 26A Vacuolar protein sorting-associated protein 29 Vacuolar protein sorting-associated protein 35	O00744 O00755 O14904 O14905 O60493 O75436 O96014 P04628 P09544 P41221 P56703 P56704 P56705 P56706 Q5T9L3 Q93097 Q93098 Q96QK1 Q9GZT5 Q9H1J5 Q9H1J7 Q9H237 Q9UBQ0 Q9UBV4 Q9Y3A6 Q9Y6F9	C1orf139 GPR177 INT1 INT1L1 INT4 IRP MEM3 MG61 PORC PORCN PPN SNX3 TMED5 VPS26 VPS26A VPS29 VPS35 WLS WNT1 WNT10A WNT10B WNT11 WNT12 WNT13 WNT14 WNT14B WNT15 WNT16 WNT2 WNT2B WNT3 WNT3A WNT4 WNT5A WNT5B WNT6 WNT7A WNT7B WNT8A WNT8B WNT8D WNT9A WNT9B	Homo sapiens (human)
Interconversion of nucleotide di- and triphosphates	Adenylate kinase 2, mitochondrial Adenylate kinase 4, mitochondrial Adenylate kinase 7 Adenylate kinase 8 Adenylate kinase 9 Adenylate kinase isoenzyme 1 Adenylate kinase isoenzyme 5 Adenylate kinase isoenzyme 6 CTP synthase 1 CTP synthase 2 Deoxycytidylate deaminase Glutaredoxin-1 Guanylate kinase NAD(P)H pyrophosphatase NUDT13, mitochondrial Nucleoside diphosphate kinase 3 Nucleoside diphosphate kinase A Nucleoside diphosphate kinase B Nucleoside diphosphate kinase, mitochondrial Putative nucleoside diphosphate kinase Ribonucleoside-diphosphate reductase large subunit Ribonucleoside-diphosphate reductase subunit M2 B Ribonucleoside-diphosphate reductase subunit M2 Thioredoxin reductase 1, cytoplasmic Thioredoxin Thymidylate kinase Thymidylate synthase UMP-CMP kinase dCTP pyrophosphatase 1	O00746 O60361 P00568 P04818 P10599 P15531 P17812 P22392 P23919 P23921 P27144 P30085 P31350 P32321 P35754 P54819 Q13232 Q16774 Q16881 Q5TCS8 Q7LG56 Q86X67 Q96M32 Q96MA6 Q9H773 Q9NRF8 Q9Y3D8 Q9Y6K8	ADK2 AK1 AK2 AK3 AK3L1 AK4 AK5 AK6 AK7 AK8 AK9 AKD1 AKD2 C6orf199 C6orf224 C9orf98 CDC8 CINAP CMK CMPK CMPK1 CTPS CTPS1 CTPS2 DCTD DCTPP1 DTYMK GLRX GMK GMPK GRIM12 GRX GUK1 KDRF NDPKA NM23 NM23B NM23D NME1 NME2 NME2P1 NME3 NME4 NUDT13 P53R2 RR1 RR2 RRM1 RRM2 RRM2B TMPK TRDX TRX TRX1 TS TXN TXNRD1 TYMK TYMS UCK UMK UMPK XTP3TPA	Homo sapiens (human)
Aspirin ADME	ATP-binding cassette sub-family C member 2 ATP-binding cassette sub-family C member 3 Acyl-coenzyme A synthetase ACSM2A, mitochondrial Acyl-coenzyme A synthetase ACSM2B, mitochondrial Acyl-coenzyme A synthetase ACSM4, mitochondrial Acyl-coenzyme A synthetase ACSM5, mitochondrial Albumin Basigin Cholinesterase Cocaine esterase Cytochrome P450 2C19 Cytochrome P450 2C8 Cytochrome P450 2C9 Cytochrome P450 2D6 Cytochrome P450 2E1 Cytochrome P450 3A4 Glycine N-acyltransferase-like protein 1 Glycine N-acyltransferase-like protein 2 Glycine N-acyltransferase-like protein 3 Glycine N-acyltransferase Liver carboxylesterase 1 Monocarboxylate transporter 1 Solute carrier family 22 member 7 UDP-glucuronosyltransferase 1-6 UDP-glucuronosyltransferase 1A1 UDP-glucuronosyltransferase 1A3 UDP-glucuronosyltransferase 1A4 UDP-glucuronosyltransferase 1A5 UDP-glucuronosyltransferase 1A7 UDP-glucuronosyltransferase 1A8 UDP-glucuronosyltransferase 1A9 UDP-glucuronosyltransferase 2A1 UDP-glucuronosyltransferase 2A2 UDP-glucuronosyltransferase 2A3 UDP-glucuronosyltransferase 2B10 UDP-glucuronosyltransferase 2B11 UDP-glucuronosyltransferase 2B15 UDP-glucuronosyltransferase 2B17 UDP-glucuronosyltransferase 2B28 UDP-glucuronosyltransferase 2B4 UDP-glucuronosyltransferase 2B7 UDP-glucuronosyltransferase 3A1 UDP-glucuronosyltransferase 3A2	O00748 O15438 O60656 O75310 O75795 P02768 P05181 P06133 P06276 P08684 P0C7M7 P0DTE4 P0DTE5 P10632 P10635 P11712 P16662 P19224 P22309 P22310 P23141 P33261 P35503 P35504 P35613 P36537 P53985 P54855 Q08AH3 Q3SY77 Q5SZD4 Q68CK6 Q6IB77 Q6NUN0 Q6NUS8 Q6UWM9 Q8WU03 Q92887 Q969I3 Q9BY64 Q9HAW7 Q9HAW9 Q9Y694	ABCC2 ABCC3 ACGNAT ACSM2 ACSM2A ACSM2B ACSM4 ACSM5 ALB BCHE BSG C6orf140 CAT CES1 CES2 CHE1 CMOAT CMOAT1 CMOAT2 CMRP CYP2C10 CYP2C19 CYP2C8 CYP2C9 CYP2D6 CYP2DL1 CYP2E CYP2E1 CYP3A3 CYP3A4 GAT GLYAT GLYATL1 GLYATL2 GLYATL3 GNAT GNT1 ICE MACS2 MACS3 MCT1 MLP2 MRP2 MRP3 NLT OAT2 SES1 SLC16A1 SLC22A7 UGT1 UGT1A1 UGT1A3 UGT1A4 UGT1A5 UGT1A6 UGT1A7 UGT1A8 UGT1A9 UGT2A1 UGT2A2 UGT2A3 UGT2B10 UGT2B11 UGT2B15 UGT2B17 UGT2B28 UGT2B4 UGT2B7 UGT2B8 UGT3A1 UGT3A2 UGTB2B9	Homo sapiens (human)
APC-Cdc20 mediated degradation of Nek2A	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Mitotic checkpoint protein BUB3 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Mitotic spindle assembly checkpoint protein MAD2A Polyubiquitin-B Polyubiquitin-C Serine/threonine-protein kinase Nek2 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00762 O43684 O60566 P0CG47 P0CG48 P30260 P51668 P51955 P51965 P60006 P62979 P62987 Q12834 Q13042 Q13257 Q16763 Q8NHZ8 Q96DE5 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM13	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 BUB1B BUB3 BUBR1 C10orf104 C11orf51 C9orf17 CDC16 CDC20 CDC23 CDC26 CDC27 CENP-27 D0S1430E D17S978E E2EPF KIAA1406 MAD2 MAD2L1 MAD3L NEK2 NEK2A NLK1 RPS27A SFT SSK1 TSG24 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S	Homo sapiens (human)
APC/C:Cdc20 mediated degradation of mitotic proteins	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Mitotic checkpoint protein BUB3 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Mitotic spindle assembly checkpoint protein MAD2A Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S	O00762 O43684 O60566 P30260 P51668 P51965 P60006 Q12834 Q13042 Q13257 Q16763 Q8NHZ8 Q96DE5 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM13	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 BUB1B BUB3 BUBR1 C10orf104 C11orf51 C9orf17 CDC16 CDC20 CDC23 CDC26 CDC27 CENP-27 D0S1430E D17S978E E2EPF KIAA1406 MAD2 MAD2L1 MAD3L SFT SSK1 TSG24 UBC5A UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S	Homo sapiens (human)
Inactivation of APC/C via direct inhibition of the APC/C complex	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Mitotic checkpoint protein BUB3 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Mitotic spindle assembly checkpoint protein MAD2A Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S	O00762 O43684 O60566 P30260 P51668 P51965 P60006 Q12834 Q13042 Q13257 Q16763 Q8NHZ8 Q96DE5 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM13	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 BUB1B BUB3 BUBR1 C10orf104 C11orf51 C9orf17 CDC16 CDC20 CDC23 CDC26 CDC27 CENP-27 D0S1430E D17S978E E2EPF KIAA1406 MAD2 MAD2L1 MAD3L SFT SSK1 TSG24 UBC5A UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S	Homo sapiens (human)
Senescence-Associated Secretory Phenotype (SASP)	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 CCAAT/enhancer-binding protein beta Cell division cycle protein 16 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 Cyclin-dependent kinase 4 inhibitor B Cyclin-dependent kinase 4 inhibitor C Cyclin-dependent kinase 4 inhibitor D Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B Cyclin-dependent kinase inhibitor 2A Fizzy-related protein homolog Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Histone-lysine N-methyltransferase EHMT1 Histone-lysine N-methyltransferase EHMT2 Homeobox protein VENTX Insulin-like growth factor-binding protein 7 Interleukin-1 alpha Interleukin-6 Interleukin-8 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase 7 Nuclear factor NF-kappa-B p105 subunit Polyubiquitin-B Polyubiquitin-C Protein c-Fos Ribosomal protein S6 kinase alpha-1 Ribosomal protein S6 kinase alpha-2 Ribosomal protein S6 kinase alpha-3 Signal transducer and activator of transcription 3 Transcription factor Jun Transcription factor p65 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00762 O60814 O95231 P01100 P01583 P04908 P05231 P05412 P06899 P0C5Y9 P0CG47 P0CG48 P10145 P11802 P16104 P17676 P19838 P20248 P20671 P23527 P24941 P27361 P28482 P30260 P33778 P38936 P40763 P42771 P42772 P42773 P46527 P51668 P51812 P51965 P55273 P57053 P58876 P60006 P62805 P62807 P62979 P62987 P68431 P78396 P84243 Q00534 Q04206 Q13042 Q13164 Q15349 Q15418 Q16270 Q16763 Q16777 Q16778 Q6FI13 Q71DI3 Q71UI9 Q8N257 Q8NHZ8 Q93077 Q93079 Q96A08 Q96DE5 Q96KQ7 Q99877 Q99878 Q99879 Q99880 Q9BTM1 Q9H1A4 Q9H9B1 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM11 Q9UM13	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 APRF BAT8 BMK1 C10orf104 C11orf51 C6orf30 C9orf17 CAP20 CCN1 CCNA CCNA1 CCNA2 CDC16 CDC23 CDC26 CDC27 CDH1 CDK2 CDK4 CDK6 CDKN1 CDKN1A CDKN1B CDKN2 CDKN2A CDKN2B CDKN2C CDKN2D CDKN6 CEBPB CENP-27 CIP1 CXCL8 D0S1430E D17S978E E2EPF EHMT1 EHMT2 ERK1 ERK2 ERK5 EUHMTASE1 FOS FYR FZR FZR1 G0S7 G9A GLP H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 HPX42B IFNB2 IGFBP7 IL1A IL1F1 IL6 IL8 ISPK1 JUN KIAA1242 KIAA1406 KIAA1876 KIP1 KMT1C KMT1D MAC25 MAPK1 MAPK3 MAPK7 MAPKAPK1A MAPKAPK1B MAPKAPK1C MDA6 MTS1 MTS2 NFKB1 NFKB3 NG36 PIC1 PRKM1 PRKM2 PRKM3 PRKM7 PSF RELA RPS27A RPS6KA1 RPS6KA2 RPS6KA3 RSK1 RSK2 RSK3 SDI1 SFT STAT3 TCF5 TSG24 TSH2B UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S VENTX VENTX2 WAF1 p27	Homo sapiens (human)

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