Integrin signaling
|
|
|
- AKT1
- APBB1IP
- CDC25L
- CGEF1
- CGEF2
- CSK
- EPAC
- EPAC1
- EPAC2
- F8VWF
- FAK
- FAK1
- FGA
- FGB
- FGG
- FN
- FN1
- GP2B
- GP3A
- ITGA2B
- ITGAB
- ITGB3
- KIAA1027
- KREV1
- MCG7
- PDK1
- PDPK1
- PKB
- PREL1
- PTK2
- PTP1B
- PTPN1
- RAC
- RAP1A
- RAP1B
- RAPGEF3
- RAPGEF4
- RARP1
- RASGRP
- RASGRP1
- RASGRP2
- RIAM
- SHC
- SHC1
- SHCA
- SRC
- SRC1
- SYK
- TLN
- TLN1
- VWF
|
|
Activation of PKB
|
|
|
- AKT2
- C20orf97
- CTMP
- NIPK
- PDK1
- PDPK1
- SKIP3
- THEM4
- TRB3
- TRIB3
|
|
CD28 dependent PI3K/Akt signaling
|
|
|
- AKT1
- AKT2
- AKT3
- C20orf97
- CD28
- CD28LG
- CD28LG1
- CD28LG2
- CD80
- CD86
- COT
- CTMP
- ESTF
- FRAP
- FRAP1
- FRAP2
- FYN
- GBL
- GRB1
- KIAA1999
- LAB7
- LCK
- LST8
- M
- MAP3K14
- MAP3K8
- MAPKAP1
- MIP1
- MLST8
- MTOR
- N
- NIK
- NIPK
- PDK1
- PDPK1
- PIK3CA
- PIK3R1
- PIK3R2
- PIK3R3
- PKB
- PKBG
- PROTOR1
- PRR5
- RAC
- RAFT1
- RAPT1
- RICTOR
- SIN1
- SKIP3
- THEM4
- TRB3
- TRIB3
|
|
VEGFR2 mediated vascular permeability
|
|
|
- AKT1
- AKT2
- AKT3
- C20orf97
- CALM
- CALM1
- CAM
- CAM1
- CAV
- CAV1
- CDH5
- CTMP
- CTNNA1
- CTNNB
- CTNNB1
- CTNND1
- CTNNG
- DP3
- FRAP
- FRAP1
- FRAP2
- GBL
- HSP90A
- HSP90AA1
- HSPC1
- HSPCA
- JUP
- KIAA0384
- KIAA1999
- LST8
- M
- MAPKAP1
- MIP1
- MLST8
- MTOR
- N
- NIPK
- NOS3
- OPHN3
- PAK1
- PAK2
- PAK3
- PDK1
- PDPK1
- PKB
- PKBG
- PROTOR1
- PRR5
- RAC
- RAC1
- RAFT1
- RAPT1
- RICTOR
- SIN1
- SKIP3
- TC25
- THEM4
- TRB3
- TRIB3
- VAV
- VAV1
- VAV2
- VAV3
|
|
PI3K/AKT Signaling
|
|
|
- AKT1
- AKT2
- AKT3
- AREG
- AREGB
- ARHG
- BCAP
- BTC
- C20orf97
- C9orf26
- CD135
- CD19
- CD28
- CD28LG
- CD28LG1
- CD28LG2
- CD80
- CD86
- CTMP
- DER4
- DTR
- DTS
- EGF
- EGFR
- EPGN
- ERBB
- ERBB1
- ERBB2
- EREG
- ESR
- ESR1
- ESR2
- ESTRB
- FGF1
- FGF10
- FGF16
- FGF18
- FGF19
- FGF2
- FGF20
- FGF22
- FGF23
- FGF3
- FGF4
- FGF6
- FGF7
- FGF9
- FGFA
- FGFB
- FGFR4
- FLK2
- FLT3
- FLT3LG
- FRAP
- FRAP1
- FRAP2
- FRS2
- FYN
- GAB1
- GAB2
- GBL
- GGF
- GRB1
- HBEGF
- HEGFL
- HER1
- HER2
- HGF
- HGL
- HPTA
- HRGA
- HST
- HST2
- HSTF1
- HSTF2
- HYPF
- IL1F11
- IL1RL1
- IL33
- INT2
- IRAK
- IRAK1
- IRAK4
- IRS1
- IRS2
- JTK2
- KGF
- KIAA0571
- KIAA1999
- KIT
- KLB
- KS3
- LAB7
- LCK
- LST8
- M
- MAPKAP1
- MET
- MIP1
- MLN19
- MLST8
- MTOR
- MYD88
- N
- NDF
- NEU
- NFHEV
- NGL
- NIPK
- NR3A1
- NR3A2
- NRG1
- NRG2
- NRG3
- NRG4
- NTAK
- PDGF2
- PDGFB
- PDGFR
- PDGFR1
- PDGFR2
- PDGFRA
- PDGFRB
- PDK1
- PDPK1
- PIK3AP1
- PIK3C1
- PIK3CA
- PIK3CB
- PIK3CD
- PIK3R1
- PIK3R2
- PIK3R3
- PKB
- PKBG
- PROTOR1
- PRR5
- PTP2C
- PTPN11
- RAC
- RAC1
- RAC2
- RAFT1
- RAPT1
- RHEPDGFRA
- RHOG
- RICTOR
- RNF85
- SCFR
- SDGF
- SGK
- SGK1
- SHPTP2
- SIN1
- SIS
- SKIP3
- SMDF
- SRC
- SRC1
- ST2
- STK1
- STRN
- T1
- TC25
- TCRIM
- TGFA
- THEM4
- TKF
- TRAF6
- TRAT1
- TRB3
- TRIB3
- VAV
- VAV1
|
|
Sphingolipid de novo biosynthesis
|
|
|
- ABCC1
- ABCG2
- ABCP
- ADMP
- BCRP
- BCRP1
- C14orf147
- C14orf66
- C20orf38
- C3orf57
- CERS1
- CERS2
- CERS3
- CERS4
- CERS5
- CERS6
- CK1G2
- CSNK1G2
- CYB5B
- CYB5M
- DEGS1
- DEGS2
- DES1
- EPK2
- FA2H
- FAAH
- FAXDC1
- FVT1
- KDSR
- KIAA0526
- LAG1
- LASS1
- LASS2
- LASS3
- LASS4
- LASS5
- LASS6
- LCB1
- LCB2
- MFSD2B
- MLD
- MOB
- MRP
- MRP1
- MXR
- OMB5
- ORMDL1
- ORMDL2
- ORMDL3
- OSBP
- OSBP1
- PKD
- PKD1
- PKD2
- PP2CE
- PPM1L
- PRKCM
- PRKCN
- PRKD1
- PRKD2
- PRKD3
- SAMD8
- SDR35C1
- SGMS1
- SGMS2
- SK1
- SK2
- SMS1
- SMS2
- SPHK
- SPHK1
- SPHK2
- SPK
- SPNS2
- SPTLC1
- SPTLC2
- SPTLC2L
- SPTLC3
- SPTSSA
- SPTSSB
- SSSPTA
- SSSPTB
- TMEM23
- TMSG1
- UOG1
- VAP33
- VAPA
- VAPB
|
|
TYSND1 cleaves peroxisomal proteins
|
|
|
- ACAA
- ACAA1
- ACOX
- ACOX1
- AGPS
- EDH17B4
- HSD17B4
- PAHX
- PHYH
- PTHIO
- SCP2
- SDR8C1
- TYSND1
|
|
Beta-oxidation of very long chain fatty acids
|
|
|
- ABCD1
- ACAA
- ACAA1
- ACOT4
- ACOT6
- ACOT8
- ACTEIII
- ALD
- C14orf42
- DECR2
- ECHD
- EDH17B4
- EHHADH
- HSD17B4
- PDCR
- PTE1
- PTE2B
- PTEIB
- PTHIO
- SDR17C1
- SDR8C1
|
|
alpha-linolenic acid (ALA) metabolism
|
|
|
- ABCD1
- ACAA
- ACAA1
- ACOT8
- ACSL1
- ACTEIII
- ALD
- CIG30
- EDH17B4
- ELG3
- ELOVL1
- ELOVL2
- ELOVL3
- ELOVL5
- FACL1
- FACL2
- FADS1
- FADS2
- FADSD5
- HSD17B4
- LACS
- LACS1
- LACS2
- PTE1
- PTHIO
- SCP2
- SDR8C1
- SSC1
- SSC2
|
|
Mitochondrial Fatty Acid Beta-Oxidation
|
|
|
- ACAA2
- ACAD10
- ACAD11
- ACBD6
- ACBD7
- ACOT1
- ACOT11
- ACOT12
- ACOT13
- ACOT15
- ACOT2
- ACOT7
- ACOT7L
- ACOT9
- ACSF2
- BACH
- BACHL
- BFIT
- CACH
- CACH1
- CTE1
- CTMP
- DBI
- KIAA0707
- MCAT
- MT
- NDUFAB1
- PCTP
- PTE2
- PTE2A
- STARD15
- STARD2
- THEA
- THEM2
- THEM4
- THEM5
|
|
Cholesterol biosynthesis
|
|
|
- 17HSD7
- ACAT2
- ACTL
- ANG1
- ARV1
- BHLHD1
- BHLHD2
- CYP51
- CYP51A1
- DESP4
- DHCR24
- ERG1
- ERG25
- FDFT1
- FDPS
- FPS
- GGPS1
- H105E3
- HMGCS
- HMGCS1
- HSD17B7
- IDI1
- IDI2
- KIAA0018
- KIAA1293
- LBR
- LSS
- MPD
- MSMO1
- MVD
- MVK
- NSDHL
- OSC
- PDP1
- PLPP6
- PMKI
- PMVK
- PPAPDC2
- SC4MOL
- SDR37C1
- SQLE
- SREBF1
- SREBF2
- SREBP1
- SREBP2
- TM7SF2
|
|
rRNA processing in the mitochondrion
|
|
|
- ELAC2
- ERAB
- HADH2
- HPC2
- HSD17B10
- KIAA0391
- MRPP1
- MRPP2
- MRPP3
- PRORP
- RG9MTD1
- SCHAD
- SDR5C1
- TRMT10C
- XH98G2
|
|
tRNA modification in the mitochondrion
|
|
|
- ERAB
- GTPBP3
- HADH2
- HSD17B10
- IPT
- KIAA0391
- MOD5
- MRPP1
- MRPP2
- MRPP3
- MTGP1
- MTO1
- MTU1
- PRORP
- RG9MTD1
- SCHAD
- SDR5C1
- TRIT1
- TRMT1
- TRMT10C
- TRMT61B
- TRMU
- XH98G2
|
|
tRNA processing in the mitochondrion
|
|
|
- ELAC2
- ERAB
- HADH2
- HPC2
- HSD17B10
- KIAA0391
- MRPP1
- MRPP2
- MRPP3
- PRORP
- RG9MTD1
- SCHAD
- SDR5C1
- TRMT10C
- TRNT1
- XH98G2
|
|
EGR2 and SOX10-mediated initiation of Schwann cell myelination
|
|
|
- ACOD4
- ADGRG6
- ADGRV1
- BAF190A
- BHLHD2
- BRG1
- BRN2
- CYP51
- CYP51A1
- DAG1
- DMDL
- DREG
- DRP1
- DRP2
- EGR2
- GAS3
- GMA
- GPR126
- GPR98
- HDAC2
- HMGCR
- KIAA0686
- KIAA1620
- KIAA1943
- KROX20
- LAMA2
- LAMB1
- LAMB2
- LAMC1
- LAMM
- MADER
- MAG
- MASS1
- MBP
- MPZ
- NAB1
- NAB2
- OCT6
- OCT7
- OTF6
- OTF7
- PMP22
- POU3F1
- POU3F2
- PRX
- SCD2
- SCD4
- SCD5
- SMARCA4
- SNF2B
- SNF2L4
- SOX10
- SREBF2
- SREBP2
- TAZ
- TCF13
- TEAD1
- TEF1
- UTRN
- VIGR
- VLGR1
- WWTR1
- YAP1
- YAP65
|
|
Synthesis of Ketone Bodies
|
|
|
- AACS
- ACAT
- ACAT1
- ACSF1
- ACSS3
- BDH
- BDH1
- BDH2
- DHRS6
- HMGCL
- HMGCLL1
- HMGCS2
- MAT
- SDR15C1
- SDR9C1
|
|
Reactions specific to the complex N-glycan synthesis pathway
|
|
|
- CGA
- CHST10
- CHST8
- FT3B
- FUCA1
- FUT3
- FUT8
- LE
- LHB
- MAN2A1
- MAN2A2
- MANA2
- MANA2X
- MGAT2
|
|
Lewis blood group biosynthesis
|
- 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3
- 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9
- 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5
- 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6
- Alpha-(1,3)-fucosyltransferase 10
- Alpha-(1,3)-fucosyltransferase 11
- Alpha-(1,3)-fucosyltransferase 4
- Alpha-(1,3)-fucosyltransferase 7
- Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
- Beta-1,3-galactosyltransferase 1
- Beta-1,3-galactosyltransferase 2
- Beta-1,3-galactosyltransferase 4
- Beta-1,3-galactosyltransferase 5
- Beta-1,4 N-acetylgalactosaminyltransferase 2
- CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase
- CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4
- Galactoside alpha-(1,2)-fucosyltransferase 2
- Type 2 lactosamine alpha-2,3-sialyltransferase
|
|
- B3GALT1
- B3GALT2
- B3GALT4
- B3GALT5
- B4GALNT2
- CGS23
- ELFT
- FCT3A
- FT3B
- FUT10
- FUT11
- FUT2
- FUT3
- FUT4
- FUT5
- FUT6
- FUT7
- FUT9
- GALGT2
- GALT4
- LE
- NANTA3
- SEC2
- SIAT10
- SIAT4C
- SIAT6
- SIAT7F
- ST3GAL3
- ST3GAL4
- ST3GAL6
- ST6GALNAC6
- STZ
|
|
Kandutsch-Russell pathway
|
|
|
- D7SR
- DHCR24
- DHCR7
- EBP
- KIAA0018
- SC5D
- SC5DL
|
|
Bloch pathway
|
|
|
- D7SR
- DHCR24
- DHCR7
- EBP
- KIAA0018
- SC5D
- SC5DL
|
|
Regulation of lipid metabolism by PPARalpha
|
|
|
- AIB3
- ARC205
- BAF60C
- BHLHE74
- BHLHE75
- CARM1
- CBP
- CHD9
- CREBBP
- CRSP1
- CRSP200
- CTG26
- DRIP205
- DRIP230
- FABP1
- FABPL
- HCA137
- HDAC3
- HELZ2
- IRA1
- KIAA0181
- KIAA0308
- KIAA1047
- KIAA1769
- KISH2
- MED1
- NCOA1
- NCOA2
- NCOA6
- NCOA6IP
- NCOR1
- NCOR2
- NR1C1
- NR2B1
- PBP
- PIMT
- PPAR
- PPARA
- PPARBP
- PPARGBP
- PRIC285
- PRIC320
- PRMT4
- RAP250
- RB18A
- RXRA
- SIN3A
- SMARCD3
- SRC1
- SRC2
- TBL1
- TBL1X
- TBL1XR1
- TBLR1
- TGS1
- TIF2
- TRAP220
- TRBP
- TRIP2
|
|
RORA activates gene expression
|
|
|
- AIB3
- ARC205
- BAF60C
- BHLHD1
- BHLHE74
- BHLHE75
- CARM1
- CBP
- CHD9
- CPT1
- CPT1A
- CREBBP
- CRSP1
- CRSP200
- DRIP205
- DRIP230
- EP300
- HCA137
- HELZ2
- IRA1
- KIAA0181
- KIAA0308
- KIAA1769
- KISH2
- MED1
- NCOA1
- NCOA2
- NCOA6
- NCOA6IP
- NR1C1
- NR1F1
- NR2B1
- P300
- PBP
- PIMT
- PPAR
- PPARA
- PPARBP
- PPARGBP
- PRIC285
- PRIC320
- PRMT4
- RAP250
- RB18A
- RORA
- RXRA
- RZRA
- SMARCD3
- SRC1
- SRC2
- SREBF1
- SREBP1
- TBL1
- TBL1X
- TBL1XR1
- TBLR1
- TGS1
- TIF2
- TRAP220
- TRBP
- TRIP2
|
|
Circadian Clock
|
|
|
- AIB3
- ARC205
- ARNTL
- ATF2
- BAF60C
- BHLHB3
- BHLHE41
- BHLHE5
- BHLHE74
- BHLHE75
- BHLHE78
- BHLHE8
- BHLHE9
- BMAL1
- BTRC
- BTRCP
- CARM1
- CBP
- CHD9
- CLOCK
- CREB2
- CREBBP
- CREBP1
- CRSP1
- CRSP200
- CRTC1
- CRTC2
- CRTC3
- CRY1
- CRY2
- CSNK1D
- CSNK1E
- CUL1
- DEC2
- DRIP205
- DRIP230
- E4BP4
- EAR1
- EMC19
- EP300
- FBL3A
- FBW1A
- FBXL3
- FBXL3A
- FBXW1A
- GRL
- HCA137
- HCKID
- HDAC3
- HELZ2
- HIF1A
- HREV
- IL3BP1
- IRA1
- KIAA0181
- KIAA0308
- KIAA0334
- KIAA0347
- KIAA0482
- KIAA0616
- KIAA0658
- KIAA1047
- KIAA1769
- KIAA1820
- KISH2
- LEM6
- MECT1
- MED1
- MEF2C
- MEF2D
- MOP1
- MOP3
- MOP4
- NCOA1
- NCOA2
- NCOA6
- NCOA6IP
- NCOR1
- NFIL3
- NPAS2
- NR1C1
- NR1D1
- NR1F1
- NR2B1
- NR3C1
- NRIP1
- OCP2
- P300
- PASD3
- PASD4
- PASD8
- PBP
- PER
- PER1
- PER2
- PGC1
- PGC1A
- PHLL1
- PIMT
- PPAR
- PPARA
- PPARBP
- PPARGBP
- PPARGC1
- PPARGC1A
- PPP1A
- PPP1CA
- PPP1CB
- PPP1CC
- PRIC285
- PRIC320
- PRMT4
- RAI1
- RAP250
- RB18A
- RBM4
- RBM4A
- RIGUI
- RORA
- RPS27A
- RXRA
- RZRA
- SHARP1
- SIK
- SIK1
- SIR2L1
- SIRT1
- SKP1
- SKP1A
- SMARCD3
- SNF1LK
- SRC1
- SRC2
- TBL1
- TBL1X
- TBL1XR1
- TBLR1
- TCEB1L
- TGS1
- THRAL
- TIF2
- TORC1
- TORC2
- TORC3
- TRAP220
- TRBP
- TRIP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- WAMTP1
|
|
BMAL1:CLOCK,NPAS2 activates circadian gene expression
|
|
|
- AIB3
- ARC205
- ARNTL
- ARNTL2
- ARVP
- AVP
- BAF60C
- BHLHB2
- BHLHB3
- BHLHE40
- BHLHE41
- BHLHE5
- BHLHE6
- BHLHE74
- BHLHE75
- BHLHE8
- BHLHE9
- BMAL1
- BMAL2
- CARM1
- CBP
- CCR4
- CCRN4L
- CHD9
- CLIF
- CLOCK
- CREBBP
- CRSP1
- CRSP200
- DBP
- DEC1
- DEC2
- DRIP205
- DRIP230
- F7
- HCA137
- HELZ2
- IRA1
- KIAA0181
- KIAA0308
- KIAA0334
- KIAA1769
- KISH2
- KKLF
- KLF15
- MED1
- MOP3
- MOP4
- MOP9
- NAMPT
- NCOA1
- NCOA2
- NCOA6
- NCOA6IP
- NOC
- NOCT
- NPAS2
- NR1C1
- NR2B1
- PAI1
- PASD3
- PASD4
- PASD9
- PBEF
- PBEF1
- PBP
- PIMT
- PLANH1
- PPAR
- PPARA
- PPARBP
- PPARGBP
- PRIC285
- PRIC320
- PRMT4
- RAP250
- RB18A
- RXRA
- SERPINE1
- SHARP1
- SHARP2
- SMARCD3
- SRC1
- SRC2
- STRA13
- TBL1
- TBL1X
- TBL1XR1
- TBLR1
- TGS1
- TIF2
- TRAP220
- TRBP
- TRIP2
- VP
|
|
Heme signaling
|
|
|
- AIB3
- APOA1
- APOB
- ARC205
- ARNTL
- ATF2
- BACH1
- BAF60C
- BHLHE5
- BHLHE74
- BHLHE75
- BHLHE8
- BHLHE9
- BMAL1
- CARM1
- CBP
- CHD9
- CLEC1B
- CLEC2
- CLOCK
- CREB2
- CREBBP
- CREBP1
- CRM1
- CRSP1
- CRSP200
- CRTC1
- CRTC2
- CRTC3
- DG6
- DRIP205
- DRIP230
- EAR1
- EP300
- ESOP1
- G21
- HBA1
- HBA2
- HBB
- HCA137
- HCP1
- HDAC3
- HELZ2
- HMOX1
- HO
- HO1
- HREV
- IRA1
- KIAA0181
- KIAA0308
- KIAA0334
- KIAA0616
- KIAA1047
- KIAA1769
- KIAA1820
- KISH2
- LEM6
- LY96
- MAFK
- MD2
- MECT1
- MED1
- MEF2C
- MEF2D
- MOP3
- MOP4
- NCOA1
- NCOA2
- NCOA6
- NCOA6IP
- NCOR1
- NFE2L2
- NPAS2
- NR1C1
- NR1D1
- NR1F1
- NR2B1
- NRF2
- NRIP1
- P300
- PASD3
- PASD4
- PBP
- PCFT
- PGC1
- PGC1A
- PGRMC2
- PIMT
- PMBP
- PPAR
- PPARA
- PPARBP
- PPARGBP
- PPARGC1
- PPARGC1A
- PRIC285
- PRIC320
- PRMT4
- RAI1
- RAP250
- RB18A
- RORA
- RXRA
- RZRA
- SIR2L1
- SIRT1
- SLC46A1
- SMARCD3
- SRC1
- SRC2
- TBL1
- TBL1X
- TBL1XR1
- TBLR1
- TGS1
- THRAL
- TIF2
- TLR4
- TORC1
- TORC2
- TORC3
- TRAP220
- TRBP
- TRIP2
- WAMTP1
- XPO1
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