GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1826 - 1850** of **2090** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Integrin signaling	3-phosphoinositide-dependent protein kinase 1 Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin Focal adhesion kinase 1 Integrin alpha-IIb Integrin beta-3 Proto-oncogene tyrosine-protein kinase Src RAC-alpha serine/threonine-protein kinase RAS guanyl-releasing protein 1 RAS guanyl-releasing protein 2 Rap guanine nucleotide exchange factor 3 Rap guanine nucleotide exchange factor 4 Ras-related protein Rap-1A Ras-related protein Rap-1b SHC-transforming protein 1 Talin-1 Tyrosine-protein kinase CSK Tyrosine-protein kinase SYK Tyrosine-protein phosphatase non-receptor type 1 von Willebrand factor	O15530 O95267 O95398 P02671 P02675 P02679 P02751 P04275 P05106 P08514 P12931 P18031 P29353 P31749 P41240 P43405 P61224 P62834 Q05397 Q7LDG7 Q7Z5R6 Q8WZA2 Q9Y490	AKT1 APBB1IP CDC25L CGEF1 CGEF2 CSK EPAC EPAC1 EPAC2 F8VWF FAK FAK1 FGA FGB FGG FN FN1 GP2B GP3A ITGA2B ITGAB ITGB3 KIAA1027 KREV1 MCG7 PDK1 PDPK1 PKB PREL1 PTK2 PTP1B PTPN1 RAC RAP1A RAP1B RAPGEF3 RAPGEF4 RARP1 RASGRP RASGRP1 RASGRP2 RIAM SHC SHC1 SHCA SRC SRC1 SYK TLN TLN1 VWF	Homo sapiens (human)
Activation of PKB	3-phosphoinositide-dependent protein kinase 1 Acyl-coenzyme A thioesterase THEM4 RAC-beta serine/threonine-protein kinase Tribbles homolog 3	O15530 P31751 Q5T1C6 Q96RU7	AKT2 C20orf97 CTMP NIPK PDK1 PDPK1 SKIP3 THEM4 TRB3 TRIB3	Homo sapiens (human)
CD28 dependent PI3K/Akt signaling	3-phosphoinositide-dependent protein kinase 1 Acyl-coenzyme A thioesterase THEM4 Membrane protein Mitogen-activated protein kinase kinase kinase 14 Mitogen-activated protein kinase kinase kinase 8 Nucleoprotein Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Proline-rich protein 5 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Rapamycin-insensitive companion of mTOR Serine/threonine-protein kinase mTOR T-cell-specific surface glycoprotein CD28 T-lymphocyte activation antigen CD80 T-lymphocyte activation antigen CD86 Target of rapamycin complex 2 subunit MAPKAP1 Target of rapamycin complex subunit LST8 Tribbles homolog 3 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lck	O00459 O15530 P06239 P06241 P0DTC5 P0DTC9 P10747 P27986 P31749 P31751 P33681 P41279 P42081 P42336 P42345 P85299 Q5T1C6 Q6R327 Q92569 Q96RU7 Q99558 Q9BPZ7 Q9BVC4 Q9Y243	AKT1 AKT2 AKT3 C20orf97 CD28 CD28LG CD28LG1 CD28LG2 CD80 CD86 COT CTMP ESTF FRAP FRAP1 FRAP2 FYN GBL GRB1 KIAA1999 LAB7 LCK LST8 M MAP3K14 MAP3K8 MAPKAP1 MIP1 MLST8 MTOR N NIK NIPK PDK1 PDPK1 PIK3CA PIK3R1 PIK3R2 PIK3R3 PKB PKBG PROTOR1 PRR5 RAC RAFT1 RAPT1 RICTOR SIN1 SKIP3 THEM4 TRB3 TRIB3	Homo sapiens (human)
VEGFR2 mediated vascular permeability	3-phosphoinositide-dependent protein kinase 1 Acyl-coenzyme A thioesterase THEM4 Cadherin-5 Calmodulin-1 Catenin alpha-1 Catenin beta-1 Catenin delta-1 Caveolin-1 Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Heat shock protein HSP 90-alpha Junction plakoglobin Membrane protein Nitric oxide synthase 3 Nucleoprotein Proline-rich protein 5 Proto-oncogene vav RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Rapamycin-insensitive companion of mTOR Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Serine/threonine-protein kinase mTOR Target of rapamycin complex 2 subunit MAPKAP1 Target of rapamycin complex subunit LST8 Tribbles homolog 3	O15530 O60716 O75914 P07900 P0DP23 P0DTC5 P0DTC9 P14923 P15498 P29474 P31749 P31751 P33151 P35221 P35222 P42345 P52735 P63000 P85299 Q03135 Q13153 Q13177 Q5T1C6 Q6R327 Q96RU7 Q9BPZ7 Q9BVC4 Q9UKW4 Q9Y243	AKT1 AKT2 AKT3 C20orf97 CALM CALM1 CAM CAM1 CAV CAV1 CDH5 CTMP CTNNA1 CTNNB CTNNB1 CTNND1 CTNNG DP3 FRAP FRAP1 FRAP2 GBL HSP90A HSP90AA1 HSPC1 HSPCA JUP KIAA0384 KIAA1999 LST8 M MAPKAP1 MIP1 MLST8 MTOR N NIPK NOS3 OPHN3 PAK1 PAK2 PAK3 PDK1 PDPK1 PKB PKBG PROTOR1 PRR5 RAC RAC1 RAFT1 RAPT1 RICTOR SIN1 SKIP3 TC25 THEM4 TRB3 TRIB3 VAV VAV1 VAV2 VAV3	Homo sapiens (human)
PI3K/AKT Signaling	3-phosphoinositide-dependent protein kinase 1 Acyl-coenzyme A thioesterase THEM4 Amphiregulin B-lymphocyte antigen CD19 Beta-klotho Epidermal growth factor receptor Epigen Estrogen receptor beta Estrogen receptor Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 19 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fms-related tyrosine kinase 3 ligand GRB2-associated-binding protein 1 GRB2-associated-binding protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Insulin receptor substrate 1 Insulin receptor substrate 2 Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-like 1 Interleukin-33 Mast/stem cell growth factor receptor Kit Membrane protein Myeloid differentiation primary response protein MyD88 Nucleoprotein Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Phosphoinositide 3-kinase adapter protein 1 Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit B Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Proline-rich protein 5 Proto-oncogene tyrosine-protein kinase Src Proto-oncogene vav Protransforming growth factor alpha RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Rapamycin-insensitive companion of mTOR Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 2 Receptor tyrosine-protein kinase erbB-2 Receptor-type tyrosine-protein kinase FLT3 Rho-related GTP-binding protein RhoG Serine/threonine-protein kinase Sgk1 Serine/threonine-protein kinase mTOR Striatin T-cell receptor-associated transmembrane adapter 1 T-cell-specific surface glycoprotein CD28 T-lymphocyte activation antigen CD80 T-lymphocyte activation antigen CD86 TNF receptor-associated factor 6 Target of rapamycin complex 2 subunit MAPKAP1 Target of rapamycin complex subunit LST8 Tribbles homolog 3 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lck Tyrosine-protein phosphatase non-receptor type 11	O00141 O00329 O00459 O14511 O14944 O15520 O15530 O43320 O43815 O76093 O95750 O95760 P00533 P01127 P01133 P01135 P03372 P04626 P05230 P06239 P06241 P08581 P08620 P09038 P09619 P0DTC5 P0DTC9 P10721 P10747 P10767 P11487 P12931 P14210 P15153 P15391 P15498 P15514 P16234 P21781 P22455 P27986 P31371 P31749 P31751 P33681 P35070 P35568 P36888 P42081 P42336 P42338 P42345 P49771 P51617 P56975 P63000 P84095 P85299 Q01638 Q02297 Q06124 Q13480 Q5T1C6 Q6PIZ9 Q6R327 Q6UW88 Q6ZUJ8 Q86Z14 Q8WU20 Q8WWG1 Q92569 Q92731 Q96RU7 Q99075 Q99836 Q9BPZ7 Q9BVC4 Q9GZV9 Q9HCT0 Q9NP95 Q9NWZ3 Q9UQC2 Q9Y243 Q9Y4H2 Q9Y4K3	AKT1 AKT2 AKT3 AREG AREGB ARHG BCAP BTC C20orf97 C9orf26 CD135 CD19 CD28 CD28LG CD28LG1 CD28LG2 CD80 CD86 CTMP DER4 DTR DTS EGF EGFR EPGN ERBB ERBB1 ERBB2 EREG ESR ESR1 ESR2 ESTRB FGF1 FGF10 FGF16 FGF18 FGF19 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB FGFR4 FLK2 FLT3 FLT3LG FRAP FRAP1 FRAP2 FRS2 FYN GAB1 GAB2 GBL GGF GRB1 HBEGF HEGFL HER1 HER2 HGF HGL HPTA HRGA HST HST2 HSTF1 HSTF2 HYPF IL1F11 IL1RL1 IL33 INT2 IRAK IRAK1 IRAK4 IRS1 IRS2 JTK2 KGF KIAA0571 KIAA1999 KIT KLB KS3 LAB7 LCK LST8 M MAPKAP1 MET MIP1 MLN19 MLST8 MTOR MYD88 N NDF NEU NFHEV NGL NIPK NR3A1 NR3A2 NRG1 NRG2 NRG3 NRG4 NTAK PDGF2 PDGFB PDGFR PDGFR1 PDGFR2 PDGFRA PDGFRB PDK1 PDPK1 PIK3AP1 PIK3C1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PKB PKBG PROTOR1 PRR5 PTP2C PTPN11 RAC RAC1 RAC2 RAFT1 RAPT1 RHEPDGFRA RHOG RICTOR RNF85 SCFR SDGF SGK SGK1 SHPTP2 SIN1 SIS SKIP3 SMDF SRC SRC1 ST2 STK1 STRN T1 TC25 TCRIM TGFA THEM4 TKF TRAF6 TRAT1 TRB3 TRIB3 VAV VAV1	Homo sapiens (human)
Sphingolipid de novo biosynthesis	3-ketodihydrosphingosine reductase Broad substrate specificity ATP-binding cassette transporter ABCG2 Casein kinase I isoform gamma-2 Ceramide synthase 1 Ceramide synthase 2 Ceramide synthase 3 Ceramide synthase 4 Ceramide synthase 5 Ceramide synthase 6 Cytochrome b5 type B Fatty acid 2-hydroxylase Multidrug resistance-associated protein 1 ORM1-like protein 1 ORM1-like protein 2 ORM1-like protein 3 Oxysterol-binding protein 1 Phosphatidylcholine Phosphatidylcholine Protein phosphatase 1L Serine palmitoyltransferase 1 Serine palmitoyltransferase 2 Serine palmitoyltransferase 3 Serine palmitoyltransferase small subunit A Serine palmitoyltransferase small subunit B Serine/threonine-protein kinase D1 Serine/threonine-protein kinase D2 Serine/threonine-protein kinase D3 Sphingolipid delta(4)-desaturase DES1 Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 Sphingomyelin synthase-related protein 1 Sphingosine kinase 1 Sphingosine kinase 2 Sphingosine-1-phosphate transporter MFSD2B Sphingosine-1-phosphate transporter SPNS2 Vesicle-associated membrane protein-associated protein A Vesicle-associated membrane protein-associated protein B/C	A6NFX1 O15121 O15269 O15270 O43169 O94806 O95292 P22059 P27544 P33527 P78368 Q06136 Q15139 Q53FV1 Q5SGD2 Q6QHC5 Q6ZMG9 Q7L5A8 Q86VZ5 Q8IU89 Q8IVW8 Q8N138 Q8N5B7 Q8NFR3 Q8NHU3 Q969W0 Q96G23 Q96LT4 Q9BZL6 Q9HA82 Q9NRA0 Q9NUV7 Q9NYA1 Q9P0L0 Q9P0S3 Q9UNQ0	ABCC1 ABCG2 ABCP ADMP BCRP BCRP1 C14orf147 C14orf66 C20orf38 C3orf57 CERS1 CERS2 CERS3 CERS4 CERS5 CERS6 CK1G2 CSNK1G2 CYB5B CYB5M DEGS1 DEGS2 DES1 EPK2 FA2H FAAH FAXDC1 FVT1 KDSR KIAA0526 LAG1 LASS1 LASS2 LASS3 LASS4 LASS5 LASS6 LCB1 LCB2 MFSD2B MLD MOB MRP MRP1 MXR OMB5 ORMDL1 ORMDL2 ORMDL3 OSBP OSBP1 PKD PKD1 PKD2 PP2CE PPM1L PRKCM PRKCN PRKD1 PRKD2 PRKD3 SAMD8 SDR35C1 SGMS1 SGMS2 SK1 SK2 SMS1 SMS2 SPHK SPHK1 SPHK2 SPK SPNS2 SPTLC1 SPTLC2 SPTLC2L SPTLC3 SPTSSA SPTSSB SSSPTA SSSPTB TMEM23 TMSG1 UOG1 VAP33 VAPA VAPB	Homo sapiens (human)
TYSND1 cleaves peroxisomal proteins	3-ketoacyl-CoA thiolase, peroxisomal Alkyldihydroxyacetonephosphate synthase, peroxisomal Peroxisomal acyl-coenzyme A oxidase 1 Peroxisomal leader peptide-processing protease Peroxisomal multifunctional enzyme type 2 Phytanoyl-CoA dioxygenase, peroxisomal Sterol carrier protein 2	O00116 O14832 P09110 P22307 P51659 Q15067 Q2T9J0	ACAA ACAA1 ACOX ACOX1 AGPS EDH17B4 HSD17B4 PAHX PHYH PTHIO SCP2 SDR8C1 TYSND1	Homo sapiens (human)
Beta-oxidation of very long chain fatty acids	3-ketoacyl-CoA thiolase, peroxisomal ATP-binding cassette sub-family D member 1 Acyl-coenzyme A thioesterase 6 Acyl-coenzyme A thioesterase 8 Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] Peroxisomal bifunctional enzyme Peroxisomal multifunctional enzyme type 2 Peroxisomal succinyl-coenzyme A thioesterase	O14734 P09110 P33897 P51659 Q08426 Q3I5F7 Q8N9L9 Q9NUI1	ABCD1 ACAA ACAA1 ACOT4 ACOT6 ACOT8 ACTEIII ALD C14orf42 DECR2 ECHD EDH17B4 EHHADH HSD17B4 PDCR PTE1 PTE2B PTEIB PTHIO SDR17C1 SDR8C1	Homo sapiens (human)
alpha-linolenic acid (ALA) metabolism	3-ketoacyl-CoA thiolase, peroxisomal ATP-binding cassette sub-family D member 1 Acyl-CoA (8-3)-desaturase Acyl-CoA 6-desaturase Acyl-coenzyme A thioesterase 8 Long-chain-fatty-acid--CoA ligase 1 Peroxisomal multifunctional enzyme type 2 Sterol carrier protein 2 Very long chain fatty acid elongase 1 Very long chain fatty acid elongase 2 Very long chain fatty acid elongase 3 Very long chain fatty acid elongase 5	O14734 O60427 O95864 P09110 P22307 P33121 P33897 P51659 Q9BW60 Q9HB03 Q9NXB9 Q9NYP7	ABCD1 ACAA ACAA1 ACOT8 ACSL1 ACTEIII ALD CIG30 EDH17B4 ELG3 ELOVL1 ELOVL2 ELOVL3 ELOVL5 FACL1 FACL2 FADS1 FADS2 FADSD5 HSD17B4 LACS LACS1 LACS2 PTE1 PTHIO SCP2 SDR8C1 SSC1 SSC2	Homo sapiens (human)
Mitochondrial Fatty Acid Beta-Oxidation	3-ketoacyl-CoA thiolase, mitochondrial Acetyl-coenzyme A thioesterase Acyl carrier protein, mitochondrial Acyl-CoA dehydrogenase family member 10 Acyl-CoA dehydrogenase family member 11 Acyl-CoA-binding domain-containing protein 6 Acyl-CoA-binding domain-containing protein 7 Acyl-CoA-binding protein Acyl-coenzyme A thioesterase 11 Acyl-coenzyme A thioesterase 13 Acyl-coenzyme A thioesterase 1 Acyl-coenzyme A thioesterase 2, mitochondrial Acyl-coenzyme A thioesterase 9, mitochondrial Acyl-coenzyme A thioesterase THEM4 Acyl-coenzyme A thioesterase THEM5 Cytosolic acyl coenzyme A thioester hydrolase Malonyl-CoA-acyl carrier protein transacylase, mitochondrial Medium-chain acyl-CoA ligase ACSF2, mitochondrial Phosphatidylcholine transfer protein Putative cytosolic acyl coenzyme A thioester hydrolase-like	O00154 O14561 P07108 P42765 P49753 Q5T1C6 Q6JQN1 Q6ZUV0 Q709F0 Q86TX2 Q8IVS2 Q8N1Q8 Q8N6N7 Q8WXI4 Q8WYK0 Q96CM8 Q9BR61 Q9NPJ3 Q9UKL6 Q9Y305	ACAA2 ACAD10 ACAD11 ACBD6 ACBD7 ACOT1 ACOT11 ACOT12 ACOT13 ACOT15 ACOT2 ACOT7 ACOT7L ACOT9 ACSF2 BACH BACHL BFIT CACH CACH1 CTE1 CTMP DBI KIAA0707 MCAT MT NDUFAB1 PCTP PTE2 PTE2A STARD15 STARD2 THEA THEM2 THEM4 THEM5	Homo sapiens (human)
Cholesterol biosynthesis	3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 Acetyl-CoA acetyltransferase, cytosolic Delta(14)-sterol reductase LBR Delta(14)-sterol reductase TM7SF2 Delta(24)-sterol reductase Diphosphomevalonate decarboxylase Farnesyl pyrophosphate synthase Geranylgeranyl pyrophosphate synthase Hydroxymethylglutaryl-CoA synthase, cytoplasmic Isopentenyl-diphosphate Delta-isomerase 1 Isopentenyl-diphosphate delta-isomerase 2 Lanosterol 14-alpha demethylase Lanosterol synthase Methylsterol monooxygenase 1 Mevalonate kinase Phosphomevalonate kinase Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6 Protein ARV1 Squalene monooxygenase Squalene synthase Sterol regulatory element-binding protein 1 Sterol regulatory element-binding protein 2 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating	O76062 O95749 P14324 P36956 P37268 P48449 P53602 P56937 Q01581 Q03426 Q12772 Q13907 Q14534 Q14739 Q15126 Q15392 Q15738 Q15800 Q16850 Q8IY26 Q9BWD1 Q9BXS1 Q9H2C2	17HSD7 ACAT2 ACTL ANG1 ARV1 BHLHD1 BHLHD2 CYP51 CYP51A1 DESP4 DHCR24 ERG1 ERG25 FDFT1 FDPS FPS GGPS1 H105E3 HMGCS HMGCS1 HSD17B7 IDI1 IDI2 KIAA0018 KIAA1293 LBR LSS MPD MSMO1 MVD MVK NSDHL OSC PDP1 PLPP6 PMKI PMVK PPAPDC2 SC4MOL SDR37C1 SQLE SREBF1 SREBF2 SREBP1 SREBP2 TM7SF2	Homo sapiens (human)
rRNA processing in the mitochondrion	3-hydroxyacyl-CoA dehydrogenase type-2 Mitochondrial ribonuclease P catalytic subunit Zinc phosphodiesterase ELAC protein 2 tRNA methyltransferase 10 homolog C	O15091 Q7L0Y3 Q99714 Q9BQ52	ELAC2 ERAB HADH2 HPC2 HSD17B10 KIAA0391 MRPP1 MRPP2 MRPP3 PRORP RG9MTD1 SCHAD SDR5C1 TRMT10C XH98G2	Homo sapiens (human)
tRNA modification in the mitochondrion	3-hydroxyacyl-CoA dehydrogenase type-2 Mitochondrial ribonuclease P catalytic subunit Mitochondrial tRNA-specific 2-thiouridylase 1 Protein MTO1 homolog, mitochondrial tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial tRNA dimethylallyltransferase tRNA methyltransferase 10 homolog C tRNA modification GTPase GTPBP3, mitochondrial	O15091 O75648 Q7L0Y3 Q969Y2 Q99714 Q9BVS5 Q9H3H1 Q9Y2Z2	ERAB GTPBP3 HADH2 HSD17B10 IPT KIAA0391 MOD5 MRPP1 MRPP2 MRPP3 MTGP1 MTO1 MTU1 PRORP RG9MTD1 SCHAD SDR5C1 TRIT1 TRMT1 TRMT10C TRMT61B TRMU XH98G2	Homo sapiens (human)
tRNA processing in the mitochondrion	3-hydroxyacyl-CoA dehydrogenase type-2 CCA tRNA nucleotidyltransferase 1, mitochondrial Mitochondrial ribonuclease P catalytic subunit Zinc phosphodiesterase ELAC protein 2 tRNA methyltransferase 10 homolog C	O15091 Q7L0Y3 Q96Q11 Q99714 Q9BQ52	ELAC2 ERAB HADH2 HPC2 HSD17B10 KIAA0391 MRPP1 MRPP2 MRPP3 PRORP RG9MTD1 SCHAD SDR5C1 TRMT10C TRNT1 XH98G2	Homo sapiens (human)
EGR2 and SOX10-mediated initiation of Schwann cell myelination	3-hydroxy-3-methylglutaryl-coenzyme A reductase Adhesion G-protein coupled receptor G6 Adhesion G-protein coupled receptor V1 Dystroglycan 1 Dystrophin-related protein 2 E3 SUMO-protein ligase EGR2 Histone deacetylase 2 Laminin subunit alpha-2 Laminin subunit beta-1 Laminin subunit gamma-1 Lanosterol 14-alpha demethylase Myelin basic protein Myelin protein P0 Myelin-associated glycoprotein NGFI-A-binding protein 1 NGFI-A-binding protein 2 POU domain, class 3, transcription factor 1 POU domain, class 3, transcription factor 2 Periaxin Peripheral myelin protein 22 Stearoyl-CoA desaturase 5 Sterol regulatory element-binding protein 2 Transcription activator BRG1 Transcription factor SOX-10 Transcriptional coactivator YAP1 Transcriptional enhancer factor TEF-1 Utrophin WW domain-containing transcription regulator protein 1	P02686 P04035 P07942 P11047 P11161 P20265 P20916 P24043 P25189 P28347 P46937 P46939 P51532 P56693 Q01453 Q03052 Q12772 Q13474 Q13506 Q14118 Q15742 Q16850 Q86SK9 Q86SQ4 Q8WXG9 Q92769 Q9BXM0 Q9GZV5	ACOD4 ADGRG6 ADGRV1 BAF190A BHLHD2 BRG1 BRN2 CYP51 CYP51A1 DAG1 DMDL DREG DRP1 DRP2 EGR2 GAS3 GMA GPR126 GPR98 HDAC2 HMGCR KIAA0686 KIAA1620 KIAA1943 KROX20 LAMA2 LAMB1 LAMB2 LAMC1 LAMM MADER MAG MASS1 MBP MPZ NAB1 NAB2 OCT6 OCT7 OTF6 OTF7 PMP22 POU3F1 POU3F2 PRX SCD2 SCD4 SCD5 SMARCA4 SNF2B SNF2L4 SOX10 SREBF2 SREBP2 TAZ TCF13 TEAD1 TEF1 UTRN VIGR VLGR1 WWTR1 YAP1 YAP65	Homo sapiens (human)
Synthesis of Ketone Bodies	3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic Acetoacetyl-CoA synthetase Acetyl-CoA acetyltransferase, mitochondrial Acyl-CoA synthetase short-chain family member 3, mitochondrial D-beta-hydroxybutyrate dehydrogenase, mitochondrial Dehydrogenase/reductase SDR family member 6 Hydroxymethylglutaryl-CoA lyase, mitochondrial Hydroxymethylglutaryl-CoA synthase, mitochondrial	P24752 P35914 P54868 Q02338 Q86V21 Q8TB92 Q9BUT1 Q9H6R3	AACS ACAT ACAT1 ACSF1 ACSS3 BDH BDH1 BDH2 DHRS6 HMGCL HMGCLL1 HMGCS2 MAT SDR15C1 SDR9C1	Homo sapiens (human)
Reactions specific to the complex N-glycan synthesis pathway	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 Alpha-(1,6)-fucosyltransferase Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Alpha-mannosidase 2 Alpha-mannosidase 2x Carbohydrate sulfotransferase 10 Carbohydrate sulfotransferase 8 Glycoprotein hormones alpha chain Lutropin subunit beta Tissue alpha-L-fucosidase	O43529 P01215 P01229 P04066 P21217 P49641 Q10469 Q16706 Q9BYC5 Q9H2A9	CGA CHST10 CHST8 FT3B FUCA1 FUT3 FUT8 LE LHB MAN2A1 MAN2A2 MANA2 MANA2X MGAT2	Homo sapiens (human)	G70323CJ G82576YO
Lewis blood group biosynthesis	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6 Alpha-(1,3)-fucosyltransferase 10 Alpha-(1,3)-fucosyltransferase 11 Alpha-(1,3)-fucosyltransferase 4 Alpha-(1,3)-fucosyltransferase 7 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 Beta-1,3-galactosyltransferase 1 Beta-1,3-galactosyltransferase 2 Beta-1,3-galactosyltransferase 4 Beta-1,3-galactosyltransferase 5 Beta-1,4 N-acetylgalactosaminyltransferase 2 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 Galactoside alpha-(1,2)-fucosyltransferase 2 Type 2 lactosamine alpha-2,3-sialyltransferase	O43825 O96024 P21217 P22083 P51993 Q10981 Q11128 Q11130 Q11203 Q11206 Q495W5 Q6P4F1 Q8NHY0 Q969X2 Q9Y231 Q9Y274 Q9Y2C3 Q9Y5Z6	B3GALT1 B3GALT2 B3GALT4 B3GALT5 B4GALNT2 CGS23 ELFT FCT3A FT3B FUT10 FUT11 FUT2 FUT3 FUT4 FUT5 FUT6 FUT7 FUT9 GALGT2 GALT4 LE NANTA3 SEC2 SIAT10 SIAT4C SIAT6 SIAT7F ST3GAL3 ST3GAL4 ST3GAL6 ST6GALNAC6 STZ	Homo sapiens (human)	G39211DH G81971FM G83633HB G90387AM G98173LG
Kandutsch-Russell pathway	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 7-dehydrocholesterol reductase Delta(24)-sterol reductase Lathosterol oxidase	O75845 Q15125 Q15392 Q9UBM7	D7SR DHCR24 DHCR7 EBP KIAA0018 SC5D SC5DL	Homo sapiens (human)
Bloch pathway	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 7-dehydrocholesterol reductase Delta(24)-sterol reductase Lathosterol oxidase	O75845 Q15125 Q15392 Q9UBM7	D7SR DHCR24 DHCR7 EBP KIAA0018 SC5D SC5DL	Homo sapiens (human)
Regulation of lipid metabolism by PPARalpha	3'-5' exoribonuclease HELZ2 CREB-binding protein Chromodomain-helicase-DNA-binding protein 9 F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Fatty acid-binding protein, liver Histone deacetylase 3 Histone-arginine methyltransferase CARM1 Mediator of RNA polymerase II transcription subunit 1 Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Nuclear receptor coactivator 6 Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 Paired amphipathic helix protein Sin3a Peroxisome proliferator-activated receptor alpha Retinoic acid receptor RXR-alpha SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 Trimethylguanosine synthase	O15379 O60907 O75376 P07148 P19793 Q07869 Q14686 Q15596 Q15648 Q15788 Q3L8U1 Q6STE5 Q86X55 Q92793 Q96RS0 Q96ST3 Q9BYK8 Q9BZK7 Q9Y618	AIB3 ARC205 BAF60C BHLHE74 BHLHE75 CARM1 CBP CHD9 CREBBP CRSP1 CRSP200 CTG26 DRIP205 DRIP230 FABP1 FABPL HCA137 HDAC3 HELZ2 IRA1 KIAA0181 KIAA0308 KIAA1047 KIAA1769 KISH2 MED1 NCOA1 NCOA2 NCOA6 NCOA6IP NCOR1 NCOR2 NR1C1 NR2B1 PBP PIMT PPAR PPARA PPARBP PPARGBP PRIC285 PRIC320 PRMT4 RAP250 RB18A RXRA SIN3A SMARCD3 SRC1 SRC2 TBL1 TBL1X TBL1XR1 TBLR1 TGS1 TIF2 TRAP220 TRBP TRIP2	Homo sapiens (human)
RORA activates gene expression	3'-5' exoribonuclease HELZ2 CREB-binding protein Carnitine O-palmitoyltransferase 1, liver isoform Chromodomain-helicase-DNA-binding protein 9 F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Histone acetyltransferase p300 Histone-arginine methyltransferase CARM1 Mediator of RNA polymerase II transcription subunit 1 Nuclear receptor ROR-alpha Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Nuclear receptor coactivator 6 Peroxisome proliferator-activated receptor alpha Retinoic acid receptor RXR-alpha SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 Sterol regulatory element-binding protein 1 Trimethylguanosine synthase	O60907 P19793 P35398 P36956 P50416 Q07869 Q09472 Q14686 Q15596 Q15648 Q15788 Q3L8U1 Q6STE5 Q86X55 Q92793 Q96RS0 Q9BYK8 Q9BZK7	AIB3 ARC205 BAF60C BHLHD1 BHLHE74 BHLHE75 CARM1 CBP CHD9 CPT1 CPT1A CREBBP CRSP1 CRSP200 DRIP205 DRIP230 EP300 HCA137 HELZ2 IRA1 KIAA0181 KIAA0308 KIAA1769 KISH2 MED1 NCOA1 NCOA2 NCOA6 NCOA6IP NR1C1 NR1F1 NR2B1 P300 PBP PIMT PPAR PPARA PPARBP PPARGBP PRIC285 PRIC320 PRMT4 RAP250 RB18A RORA RXRA RZRA SMARCD3 SRC1 SRC2 SREBF1 SREBP1 TBL1 TBL1X TBL1XR1 TBLR1 TGS1 TIF2 TRAP220 TRBP TRIP2	Homo sapiens (human)
Circadian Clock	3'-5' exoribonuclease HELZ2 Basic helix-loop-helix ARNT-like protein 1 CREB-binding protein CREB-regulated transcription coactivator 1 CREB-regulated transcription coactivator 2 CREB-regulated transcription coactivator 3 Casein kinase I isoform delta Casein kinase I isoform epsilon Chromodomain-helicase-DNA-binding protein 9 Circadian locomoter output cycles protein kaput Class E basic helix-loop-helix protein 41 Cryptochrome-1 Cryptochrome-2 Cullin-1 Cyclic AMP-dependent transcription factor ATF-2 F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 F-box/LRR-repeat protein 3 F-box/WD repeat-containing protein 1A Glucocorticoid receptor Histone acetyltransferase p300 Histone deacetylase 3 Histone-arginine methyltransferase CARM1 Hypoxia-inducible factor 1-alpha Mediator of RNA polymerase II transcription subunit 1 Myocyte-specific enhancer factor 2C Myocyte-specific enhancer factor 2D NAD-dependent protein deacetylase sirtuin-1 Neuronal PAS domain-containing protein 2 Nuclear factor interleukin-3-regulated protein Nuclear receptor ROR-alpha Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Nuclear receptor coactivator 6 Nuclear receptor corepressor 1 Nuclear receptor subfamily 1 group D member 1 Nuclear receptor-interacting protein 1 Period circadian protein homolog 1 Period circadian protein homolog 2 Peroxisome proliferator-activated receptor alpha Peroxisome proliferator-activated receptor gamma coactivator 1-alpha Polyubiquitin-B Polyubiquitin-C RNA-binding protein 4 Retinoic acid receptor RXR-alpha Retinoic acid-induced protein 1 S-phase kinase-associated protein 1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 Serine/threonine-protein kinase SIK1 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Serine/threonine-protein phosphatase PP1-beta catalytic subunit Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Trimethylguanosine synthase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00327 O15055 O15379 O15516 O15534 O60907 O75376 P04150 P0CG47 P0CG48 P15336 P19793 P20393 P35398 P36873 P48552 P48730 P49674 P57059 P62136 P62140 P62979 P62987 P63208 Q06413 Q07869 Q09472 Q13616 Q14686 Q14814 Q15596 Q15648 Q15788 Q16526 Q16649 Q16665 Q3L8U1 Q49AN0 Q53ET0 Q6STE5 Q6UUV7 Q6UUV9 Q7Z5J4 Q86X55 Q92793 Q96EB6 Q96RS0 Q99743 Q9BWF3 Q9BYK8 Q9BZK7 Q9C0J9 Q9UBK2 Q9UKT7 Q9Y297	AIB3 ARC205 ARNTL ATF2 BAF60C BHLHB3 BHLHE41 BHLHE5 BHLHE74 BHLHE75 BHLHE78 BHLHE8 BHLHE9 BMAL1 BTRC BTRCP CARM1 CBP CHD9 CLOCK CREB2 CREBBP CREBP1 CRSP1 CRSP200 CRTC1 CRTC2 CRTC3 CRY1 CRY2 CSNK1D CSNK1E CUL1 DEC2 DRIP205 DRIP230 E4BP4 EAR1 EMC19 EP300 FBL3A FBW1A FBXL3 FBXL3A FBXW1A GRL HCA137 HCKID HDAC3 HELZ2 HIF1A HREV IL3BP1 IRA1 KIAA0181 KIAA0308 KIAA0334 KIAA0347 KIAA0482 KIAA0616 KIAA0658 KIAA1047 KIAA1769 KIAA1820 KISH2 LEM6 MECT1 MED1 MEF2C MEF2D MOP1 MOP3 MOP4 NCOA1 NCOA2 NCOA6 NCOA6IP NCOR1 NFIL3 NPAS2 NR1C1 NR1D1 NR1F1 NR2B1 NR3C1 NRIP1 OCP2 P300 PASD3 PASD4 PASD8 PBP PER PER1 PER2 PGC1 PGC1A PHLL1 PIMT PPAR PPARA PPARBP PPARGBP PPARGC1 PPARGC1A PPP1A PPP1CA PPP1CB PPP1CC PRIC285 PRIC320 PRMT4 RAI1 RAP250 RB18A RBM4 RBM4A RIGUI RORA RPS27A RXRA RZRA SHARP1 SIK SIK1 SIR2L1 SIRT1 SKP1 SKP1A SMARCD3 SNF1LK SRC1 SRC2 TBL1 TBL1X TBL1XR1 TBLR1 TCEB1L TGS1 THRAL TIF2 TORC1 TORC2 TORC3 TRAP220 TRBP TRIP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WAMTP1	Homo sapiens (human)
BMAL1:CLOCK,NPAS2 activates circadian gene expression	3'-5' exoribonuclease HELZ2 Basic helix-loop-helix ARNT-like protein 1 Basic helix-loop-helix ARNT-like protein 2 CREB-binding protein Chromodomain-helicase-DNA-binding protein 9 Circadian locomoter output cycles protein kaput Class E basic helix-loop-helix protein 40 Class E basic helix-loop-helix protein 41 Coagulation factor VII D site-binding protein F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Histone-arginine methyltransferase CARM1 Krueppel-like factor 15 Mediator of RNA polymerase II transcription subunit 1 Neuronal PAS domain-containing protein 2 Nicotinamide phosphoribosyltransferase Nocturnin Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Nuclear receptor coactivator 6 Peroxisome proliferator-activated receptor alpha Plasminogen activator inhibitor 1 Retinoic acid receptor RXR-alpha SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 Trimethylguanosine synthase Vasopressin-neurophysin 2-copeptin	O00327 O14503 O15516 O60907 P01185 P05121 P08709 P19793 P43490 Q07869 Q10586 Q14686 Q15596 Q15648 Q15788 Q3L8U1 Q6STE5 Q86X55 Q8WYA1 Q92793 Q96RS0 Q99743 Q9BYK8 Q9BZK7 Q9C0J9 Q9UIH9 Q9UK39	AIB3 ARC205 ARNTL ARNTL2 ARVP AVP BAF60C BHLHB2 BHLHB3 BHLHE40 BHLHE41 BHLHE5 BHLHE6 BHLHE74 BHLHE75 BHLHE8 BHLHE9 BMAL1 BMAL2 CARM1 CBP CCR4 CCRN4L CHD9 CLIF CLOCK CREBBP CRSP1 CRSP200 DBP DEC1 DEC2 DRIP205 DRIP230 F7 HCA137 HELZ2 IRA1 KIAA0181 KIAA0308 KIAA0334 KIAA1769 KISH2 KKLF KLF15 MED1 MOP3 MOP4 MOP9 NAMPT NCOA1 NCOA2 NCOA6 NCOA6IP NOC NOCT NPAS2 NR1C1 NR2B1 PAI1 PASD3 PASD4 PASD9 PBEF PBEF1 PBP PIMT PLANH1 PPAR PPARA PPARBP PPARGBP PRIC285 PRIC320 PRMT4 RAP250 RB18A RXRA SERPINE1 SHARP1 SHARP2 SMARCD3 SRC1 SRC2 STRA13 TBL1 TBL1X TBL1XR1 TBLR1 TGS1 TIF2 TRAP220 TRBP TRIP2 VP	Homo sapiens (human)
Heme signaling	3'-5' exoribonuclease HELZ2 Apolipoprotein A-I Apolipoprotein B-100 Basic helix-loop-helix ARNT-like protein 1 C-type lectin domain family 1 member B CREB-binding protein CREB-regulated transcription coactivator 1 CREB-regulated transcription coactivator 2 CREB-regulated transcription coactivator 3 Chromodomain-helicase-DNA-binding protein 9 Circadian locomoter output cycles protein kaput Cyclic AMP-dependent transcription factor ATF-2 Exportin-1 F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Heme oxygenase 1 Hemoglobin subunit alpha Hemoglobin subunit beta Histone acetyltransferase p300 Histone deacetylase 3 Histone-arginine methyltransferase CARM1 Lymphocyte antigen 96 Mediator of RNA polymerase II transcription subunit 1 Membrane-associated progesterone receptor component 2 Myocyte-specific enhancer factor 2C Myocyte-specific enhancer factor 2D NAD-dependent protein deacetylase sirtuin-1 Neuronal PAS domain-containing protein 2 Nuclear factor erythroid 2-related factor 2 Nuclear receptor ROR-alpha Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Nuclear receptor coactivator 6 Nuclear receptor corepressor 1 Nuclear receptor subfamily 1 group D member 1 Nuclear receptor-interacting protein 1 Peroxisome proliferator-activated receptor alpha Peroxisome proliferator-activated receptor gamma coactivator 1-alpha Proton-coupled folate transporter Retinoic acid receptor RXR-alpha Retinoic acid-induced protein 1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 Toll-like receptor 4 Transcription factor MafK Transcription regulator protein BACH1 Trimethylguanosine synthase	O00206 O00327 O14867 O14980 O15173 O15379 O15516 O60675 O60907 O75376 P02647 P04114 P09601 P15336 P19793 P20393 P35398 P48552 P68871 P69905 Q06413 Q07869 Q09472 Q14686 Q14814 Q15596 Q15648 Q15788 Q16236 Q3L8U1 Q53ET0 Q6STE5 Q6UUV7 Q6UUV9 Q7Z5J4 Q86X55 Q92793 Q96EB6 Q96NT5 Q96RS0 Q99743 Q9BYK8 Q9BZK7 Q9P126 Q9UBK2 Q9Y6Y9	AIB3 APOA1 APOB ARC205 ARNTL ATF2 BACH1 BAF60C BHLHE5 BHLHE74 BHLHE75 BHLHE8 BHLHE9 BMAL1 CARM1 CBP CHD9 CLEC1B CLEC2 CLOCK CREB2 CREBBP CREBP1 CRM1 CRSP1 CRSP200 CRTC1 CRTC2 CRTC3 DG6 DRIP205 DRIP230 EAR1 EP300 ESOP1 G21 HBA1 HBA2 HBB HCA137 HCP1 HDAC3 HELZ2 HMOX1 HO HO1 HREV IRA1 KIAA0181 KIAA0308 KIAA0334 KIAA0616 KIAA1047 KIAA1769 KIAA1820 KISH2 LEM6 LY96 MAFK MD2 MECT1 MED1 MEF2C MEF2D MOP3 MOP4 NCOA1 NCOA2 NCOA6 NCOA6IP NCOR1 NFE2L2 NPAS2 NR1C1 NR1D1 NR1F1 NR2B1 NRF2 NRIP1 P300 PASD3 PASD4 PBP PCFT PGC1 PGC1A PGRMC2 PIMT PMBP PPAR PPARA PPARBP PPARGBP PPARGC1 PPARGC1A PRIC285 PRIC320 PRMT4 RAI1 RAP250 RB18A RORA RXRA RZRA SIR2L1 SIRT1 SLC46A1 SMARCD3 SRC1 SRC2 TBL1 TBL1X TBL1XR1 TBLR1 TGS1 THRAL TIF2 TLR4 TORC1 TORC2 TORC3 TRAP220 TRBP TRIP2 WAMTP1 XPO1	Homo sapiens (human)

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