GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1926 - 1950** of **2090** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	Organism	GlyTouCan ID
Collagen biosynthesis and modifying enzymes	A disintegrin and metalloproteinase with thrombospondin motifs 14 A disintegrin and metalloproteinase with thrombospondin motifs 2 A disintegrin and metalloproteinase with thrombospondin motifs 3 Bone morphogenetic protein 1 Cartilage-associated protein Collagen alpha-1(I) chain Collagen alpha-1(II) chain Collagen alpha-1(III) chain Collagen alpha-1(IV) chain Collagen alpha-1(IX) chain Collagen alpha-1(V) chain Collagen alpha-1(VI) chain Collagen alpha-1(VII) chain Collagen alpha-1(VIII) chain Collagen alpha-1(X) chain Collagen alpha-1(XI) chain Collagen alpha-1(XII) chain Collagen alpha-1(XIII) chain Collagen alpha-1(XIV) chain Collagen alpha-1(XIX) chain Collagen alpha-1(XV) chain Collagen alpha-1(XVI) chain Collagen alpha-1(XVII) chain Collagen alpha-1(XVIII) chain Collagen alpha-1(XX) chain Collagen alpha-1(XXI) chain Collagen alpha-1(XXII) chain Collagen alpha-1(XXIII) chain Collagen alpha-1(XXIV) chain Collagen alpha-1(XXV) chain Collagen alpha-1(XXVI) chain Collagen alpha-1(XXVII) chain Collagen alpha-1(XXVIII) chain Collagen alpha-2(I) chain Collagen alpha-2(IV) chain Collagen alpha-2(IX) chain Collagen alpha-2(V) chain Collagen alpha-2(VI) chain Collagen alpha-2(VIII) chain Collagen alpha-2(XI) chain Collagen alpha-3(IV) chain Collagen alpha-3(IX) chain Collagen alpha-3(V) chain Collagen alpha-3(VI) chain Collagen alpha-4(IV) chain Collagen alpha-5(IV) chain Collagen alpha-5(VI) chain Collagen alpha-6(IV) chain Collagen alpha-6(VI) chain Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 Peptidyl-prolyl cis-trans isomerase B Procollagen C-endopeptidase enhancer 1 Procollagen C-endopeptidase enhancer 2 Procollagen galactosyltransferase 1 Procollagen galactosyltransferase 2 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 Prolyl 3-hydroxylase 1 Prolyl 3-hydroxylase 2 Prolyl 3-hydroxylase 3 Prolyl 4-hydroxylase subunit alpha-1 Prolyl 4-hydroxylase subunit alpha-2 Prolyl 4-hydroxylase subunit alpha-3 Protein disulfide-isomerase Serpin H1 Tolloid-like protein 1 Tolloid-like protein 2	A6NMZ7 A8TX70 O00469 O15072 O15460 O43897 O60568 O75718 O95450 P02452 P02458 P02461 P02462 P05997 P07237 P08123 P08572 P12107 P12109 P12110 P12111 P13497 P13674 P13942 P20849 P20908 P23284 P25067 P25940 P27658 P29400 P39059 P39060 P50454 P53420 Q01955 Q02388 Q02809 Q03692 Q05707 Q07092 Q14031 Q14050 Q14055 Q14993 Q15113 Q17RW2 Q2UY09 Q32P28 Q5TAT6 Q7Z4N8 Q86Y22 Q8IVL5 Q8IVL6 Q8IYK4 Q8IZC6 Q8NBJ5 Q8NFW1 Q8WXS8 Q96A83 Q96P44 Q99715 Q9BXS0 Q9P218 Q9UKZ9 Q9UMD9 Q9Y6L7	ADAMTS14 ADAMTS2 ADAMTS3 BMP1 BP180 BPAG2 C1orf17 C3orf7 CASP CBP1 CBP2 COL10A1 COL11A1 COL11A2 COL12A1 COL12A1L COL13A1 COL14A1 COL15A1 COL16A1 COL17A1 COL18A1 COL19A1 COL1A1 COL1A2 COL1AL COL20A1 COL21A1 COL22A1 COL23A1 COL24A1 COL25A1 COL26A1 COL27A1 COL28 COL28A1 COL29A1 COL2A1 COL3A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL5A1 COL5A2 COL5A3 COL6A1 COL6A2 COL6A3 COL6A5 COL6A6 COL7A1 COL8A1 COL8A2 COL9A1 COL9A2 COL9A3 COLGALT1 COLGALT2 COLL6 CRTAP CYPB EMID2 EMU2 ERBA2L GLT25D1 GLT25D2 GROS1 HSP47 KIAA0366 KIAA0584 KIAA0932 KIAA1510 KIAA1870 LEPRE1 LEPREL1 LEPREL2 LLH MLAT4 P3H1 P3H2 P3H3 P4HA P4HA1 P4HA2 P4HA3 P4HB PCINP PCOLC PCOLCE PCOLCE2 PCPE1 PCPE2 PCPNI PDI PDIA1 PLOD PLOD1 PLOD2 PLOD3 PO4DB PPIB SERPINH1 SERPINH2 TLL TLL1 TLL2 UND VWA4	Homo sapiens (human)
NCAM1 interactions	Agrin Alpha-2,8-sialyltransferase 8B Artemin CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase Collagen alpha-1(IV) chain Collagen alpha-1(IX) chain Collagen alpha-1(VI) chain Collagen alpha-2(IV) chain Collagen alpha-2(IX) chain Collagen alpha-2(VI) chain Collagen alpha-3(IV) chain Collagen alpha-3(IX) chain Collagen alpha-3(VI) chain Collagen alpha-4(IV) chain Collagen alpha-5(IV) chain Collagen alpha-5(VI) chain Collagen alpha-6(VI) chain Contactin-2 GDNF family receptor alpha-1 GDNF family receptor alpha-2 GDNF family receptor alpha-4 Glial cell line-derived neurotrophic factor Major prion protein Neural cell adhesion molecule 1 Neurocan core protein Neurturin Persephin Voltage-dependent L-type calcium channel subunit alpha-1C Voltage-dependent L-type calcium channel subunit alpha-1D Voltage-dependent L-type calcium channel subunit alpha-1S Voltage-dependent L-type calcium channel subunit beta-1 Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent L-type calcium channel subunit beta-3 Voltage-dependent L-type calcium channel subunit beta-4 Voltage-dependent T-type calcium channel subunit alpha-1G Voltage-dependent T-type calcium channel subunit alpha-1H Voltage-dependent T-type calcium channel subunit alpha-1I	A6NMZ7 A8TX70 O00305 O00451 O00468 O14594 O43497 O60542 O95180 P02462 P04156 P08572 P12109 P12110 P12111 P13591 P20849 P29400 P39905 P53420 P54284 P56159 Q01668 Q01955 Q02246 Q02641 Q08289 Q13698 Q13936 Q14050 Q14055 Q5T4W7 Q92186 Q92187 Q99748 Q9GZZ7 Q9P0X4	AGRIN AGRN ALTPRP ARTN AXT CACH1 CACH2 CACH3 CACN1 CACN2 CACN4 CACNA1C CACNA1D CACNA1G CACNA1H CACNA1I CACNA1S CACNB1 CACNB2 CACNB3 CACNB4 CACNL1A1 CACNL1A2 CACNL1A3 CACNLB1 CACNLB2 CACNLB3 CACNLB4 CCHL1A1 CCHL1A2 CNTN2 COL29A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL6A1 COL6A2 COL6A3 COL6A5 COL6A6 COL9A1 COL9A2 COL9A3 CSPG3 EVN GDNF GDNFRA GDNFRB GFRA1 GFRA2 GFRA4 KIAA1120 KIAA1123 MYSB NCAM NCAM1 NCAN NEUR NRTN PRIP PRNP PRP PSPN PST PST1 RETL1 RETL2 SIAT8B SIAT8D ST8SIA2 ST8SIA4 STX TAG1 TAX1 TRNR1 TRNR2 VWA4	Homo sapiens (human)
DAP12 interactions	Beta-2-microglobulin C-type lectin domain family 5 member A CMRF35-like molecule 2 CMRF35-like molecule 7 HLA class I histocompatibility antigen, B alpha chain HLA class I histocompatibility antigen, C alpha chain HLA class I histocompatibility antigen, alpha chain E Killer cell immunoglobulin-like receptor 2DS2 Killer cell immunoglobulin-like receptor 2DS4 Killer cell immunoglobulin-like receptor 2DS5 Killer cell immunoglobulin-like receptor 3DS1 NKG2-C type II integral membrane protein NKG2-D type II integral membrane protein Natural cytotoxicity triggering receptor 2 Natural killer cells antigen CD94 Sialic acid-binding Ig-like lectin 14 Sialic acid-binding Ig-like lectin 15 Sialic acid-binding Ig-like lectin 16 Signal-regulatory protein beta-1 TYRO protein tyrosine kinase-binding protein Triggering receptor expressed on myeloid cells 1 Triggering receptor expressed on myeloid cells 2	A6NMB1 A8K4G0 O00241 O43914 O95944 P01889 P10321 P13747 P26717 P26718 P43631 P43632 P61769 Q08ET2 Q13241 Q14943 Q14953 Q496F6 Q6ZMC9 Q9NP99 Q9NY25 Q9NZC2	B2M CD158G CD158I CD158J CD300B CD300E CD300LB CD300LE CD33L3 CD94 CLEC5A CLECSF5 CLM2 CLM7 CMRF35A2 CMRF35A5 D12S2489E DAP12 HLA-6.2 HLA-B HLA-C HLA-E HLAB HLAC HLAE IREM2 IREM3 KARAP KIR2DS2 KIR2DS4 KIR2DS5 KIR3DS1 KKA3 KLRC2 KLRD1 KLRK1 LMIR5 LY95 MDL1 NCR2 NKAT10 NKAT5 NKAT8 NKAT9 NKG2C NKG2D SIGLEC14 SIGLEC15 SIGLEC16 SIGLECP16 SIRPB1 TREM1 TREM2 TREM5 TYROBP	Homo sapiens (human)
Protein lipoylation	Acyl carrier protein, mitochondrial Adrenodoxin, mitochondrial Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial Glycine cleavage system H protein, mitochondrial Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial Lipoyl amidotransferase LIPT1, mitochondrial Lipoyl synthase, mitochondrial NFU1 iron-sulfur cluster scaffold homolog, mitochondrial Octanoyl-[acyl-carrier-protein]	A6NK58 O14561 O43766 P10109 P10515 P11182 P23434 P36957 Q9UMS0 Q9Y234	ADX BCATE2 BCKDHE2 DBT DLAT DLST DLTA DLTS FDX1 GCSH HIRIP5 LAS LIAS LIPT1 LIPT2 NDUFAB1 NFU1	Homo sapiens (human)
Trafficking of myristoylated proteins to the cilium	ADP-ribosylation factor-like protein 3 Cystin-1 Nephrocystin-3 Protein XRP2 Protein unc-119 homolog B	A6NIH7 O75695 P36405 Q717R9 Q7Z494	ARFL3 ARL3 CYS1 KIAA2000 NPHP3 RP2 UNC119B	Homo sapiens (human)
RAC2 GTPase cycle	ARF GTPase-activating protein GIT1 ARF GTPase-activating protein GIT2 Abl interactor 1 Abl interactor 2 Actin remodeling regulator NHS Actin-binding protein WASF2 Active breakpoint cluster region-related protein Ankyrin repeat and LEM domain-containing protein 2 Armadillo repeat-containing X-linked protein 3 BAR/IMD domain-containing adapter protein 2-like 1 Breakpoint cluster region protein Caveolin-1 Cdc42 effector protein 1 Cdc42 effector protein 4 Cell division control protein 42 homolog Cell surface glycoprotein MUC18 Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytoplasmic FMR1-interacting protein 1 DEP domain-containing protein 1B Dedicator of cytokinesis protein 10 Dedicator of cytokinesis protein 1 Dedicator of cytokinesis protein 2 Dedicator of cytokinesis protein 3 Dedicator of cytokinesis protein 4 Delta(14)-sterol reductase LBR Desmoglein-2 Differentially expressed in FDCP 6 homolog Emerin Ephrin type-A receptor 2 Erbin Extended synaptotagmin-1 Granule associated Rac and RHOG effector protein 1 Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Inner nuclear membrane protein Man1 Integrin beta-1 Lamina-associated polypeptide 2, isoforms beta/gamma MAGUK p55 subfamily member 7 Membrane-associated progesterone receptor component 2 Metaxin-1 Nck-associated protein 1-like Nck-associated protein 1 Neutrophil cytosol factor 1 Neutrophil cytosol factor 2 Neutrophil cytosol factor 4 Oligophrenin-1 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phospholipase D2 Protein BRICK1 Protein ERGIC-53 Protein diaphanous homolog 3 Proto-oncogene DBL Proto-oncogene vav Rac GTPase-activating protein 1 Ragulator complex protein LAMTOR1 Ras GTPase-activating-like protein IQGAP1 Ras-related C3 botulinum toxin substrate 2 Ras-related protein Rab-7a Rho GDP-dissociation inhibitor 1 Rho GTPase-activating protein 17 Rho GTPase-activating protein 1 Rho GTPase-activating protein 21 Rho GTPase-activating protein 26 Rho GTPase-activating protein 32 Rho GTPase-activating protein 35 Rho GTPase-activating protein 39 Rho GTPase-activating protein 42 Rho GTPase-activating protein SYDE1 Rho guanine nucleotide exchange factor TIAM1 SLIT and NTRK-like protein 5 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 4 Serine/threonine-protein kinase TAO3 Serine/threonine-protein kinase VRK2 Sorting and assembly machinery component 50 homolog Starch-binding domain-containing protein 1 Switch-associated protein 70 Transferrin receptor protein 1 Triple functional domain protein Vang-like protein 1 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein-associated protein B/C	A6NI28 A7KAX9 O00459 O14939 O15063 O15173 O60890 O75962 O94991 O95210 O95292 O96013 P02786 P04839 P05556 P10911 P11274 P13498 P14598 P15153 P15498 P19878 P27986 P29317 P42167 P42336 P43121 P46940 P49257 P50402 P51149 P52565 P52735 P55160 P60953 Q00587 Q03135 Q07960 Q12979 Q13009 Q13153 Q13177 Q13505 Q14126 Q14161 Q14185 Q14739 Q15080 Q15836 Q5T2T1 Q5T5U3 Q68EM7 Q6IAA8 Q6T4R5 Q6ZW31 Q7L576 Q86XL3 Q86Y07 Q8IZD9 Q8IZP0 Q8N1I0 Q8TAA9 Q8TCU6 Q8WUW1 Q8WUY9 Q92569 Q92608 Q96BY6 Q96RT1 Q9BSJ8 Q9C0H5 Q9H0H5 Q9H2K8 Q9H3Q1 Q9H4E7 Q9NRY4 Q9NSV4 Q9NYB9 Q9UH62 Q9UH65 Q9UHR4 Q9UKW4 Q9UNA1 Q9Y2A7 Q9Y2U8 Q9Y2X7 Q9Y512 Q9Y6W5	ABI1 ABI2 ABR ALEX3 ANKLE2 ARGBPIA ARHGAP1 ARHGAP10 ARHGAP17 ARHGAP21 ARHGAP26 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP42 ARHGDIA ARMCX3 BAIAP2L1 BCR BCR1 BORG4 BORG5 BRK1 C11orf59 C3orf10 CAV CAV1 CDC42 CDC42EP1 CDC42EP4 CDC42GAP CDHF5 CEP1 CEP4 CYBA CYBB CYFIP1 D22S11 DBL DEF6 DEPDC1B DG6 DIAP3 DIAPH3 DOCK1 DOCK10 DOCK2 DOCK3 DOCK4 DPK DSG2 ECK EDMD EMD EPHA2 ERBB2IP ERBIN ERGIC53 ESYT1 F5F8D FAM62A FNRB GARRE1 GDIA1 GIT1 GIT2 GRAF GRAF3 GRB1 GRF1 GRIT GRLF1 HEM1 HEM2 IBP IQGAP1 IRTKS ITGB1 JIK KDS KIAA0051 KIAA0068 KIAA0148 KIAA0209 KIAA0299 KIAA0355 KIAA0587 KIAA0621 KIAA0640 KIAA0692 KIAA0694 KIAA0712 KIAA0716 KIAA0747 KIAA0918 KIAA1142 KIAA1225 KIAA1415 KIAA1424 KIAA1478 KIAA1688 KIAA1722 LAMTOR1 LAP2 LBR LEM4 LEMD3 LMAN1 LRRC11 MAN1 MAP3K18 MBC2 MCAM MCF2 MDF2 MGCRACGAP MOCA MPP7 MSE55 MSK12 MTX MTX1 MTXN MUC18 NAP1 NCF1 NCF2 NCF4 NCKAP1 NCKAP1L NHS NOX2 NOXA2 NOXO2 OPHN1 OPHN1L P190A P67PHOX PAK1 PAK2 PAK4 PDRO PGRMC2 PIK3CA PIK3R1 PIK3R2 PIK3R3 PLD2 PMBP PREX1 RAB7 RAB7A RAC2 RACGAP1 RHOGAP1 RICH1 RICS SAM50 SAMM50 SH3PXD1A SH3PXD4 SLITRK5 SSH3BP1 STA STB2 STBD1 SWAP70 SYB3 SYDE1 TAOK3 TFRC TIAM1 TMEM133 TMPO TRIO VAMP3 VANGL1 VAPB VAV VAV1 VAV2 VAV3 VRK2 WASF2 WAVE2 XTP8 ZIZ3 p190ARHOGAP	Homo sapiens (human)
RAC3 GTPase cycle	ARF GTPase-activating protein GIT1 ARF GTPase-activating protein GIT2 Abl interactor 1 Abl interactor 2 Actin remodeling regulator NHS Actin-binding protein WASF1 Actin-binding protein WASF2 Active breakpoint cluster region-related protein Amphoterin-induced protein 2 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 BAR/IMD domain-containing adapter protein 2-like 1 BAR/IMD domain-containing adapter protein 2 Breakpoint cluster region protein Caveolin-1 Cdc42 effector protein 1 Cell division control protein 42 homolog Cell surface glycoprotein MUC18 Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytoplasmic FMR1-interacting protein 1 DEP domain-containing protein 1B Dedicator of cytokinesis protein 10 Delta(14)-sterol reductase LBR Desmoglein-2 Emerin Ephrin type-A receptor 2 Erbin Extended synaptotagmin-1 Fermitin family homolog 2 Granule associated Rac and RHOG effector protein 1 Guanine nucleotide exchange factor VAV2 Inner nuclear membrane protein Man1 Inositol polyphosphate 5-phosphatase OCRL Integrin beta-1 Interleukin-32 Lamina-associated polypeptide 2, isoforms beta/gamma MAGUK p55 subfamily member 7 Membrane-associated progesterone receptor component 2 NADPH oxidase 1 NADPH oxidase 3 NADPH oxidase activator 1 NADPH oxidase organizer 1 Nck-associated protein 1-like Nck-associated protein 1 Neutral amino acid transporter B(0) Neutrophil cytosol factor 1 Neutrophil cytosol factor 2 Neutrophil cytosol factor 4 Oligophrenin-1 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Protein BRICK1 Protein ERGIC-53 Protein diaphanous homolog 3 Protein jagged-1 Proto-oncogene DBL Rac GTPase-activating protein 1 Ragulator complex protein LAMTOR1 Rap guanine nucleotide exchange factor 1 Ras-related C3 botulinum toxin substrate 3 Ras-related protein Rab-7a Rho GDP-dissociation inhibitor 2 Rho GTPase-activating protein 15 Rho GTPase-activating protein 17 Rho GTPase-activating protein 1 Rho GTPase-activating protein 21 Rho GTPase-activating protein 26 Rho GTPase-activating protein 32 Rho GTPase-activating protein 35 Rho GTPase-activating protein 39 Rho GTPase-activating protein 42 Rho GTPase-activating protein 5 Rho GTPase-activating protein 6 Rho GTPase-activating protein SYDE1 Rho guanine nucleotide exchange factor TIAM1 SLIT and NTRK-like protein 3 SLIT and NTRK-like protein 5 SLIT-ROBO Rho GTPase-activating protein 2 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 4 Serine/threonine-protein kinase TAO3 Serine/threonine-protein kinase VRK2 Starch-binding domain-containing protein 1 Switch-associated protein 70 Synaptobrevin homolog YKT6 Synaptosomal-associated protein 23 Transferrin receptor protein 1 Triple functional domain protein Tyrosine-protein kinase ABL2 Vang-like protein 1 Vesicle-associated membrane protein 3	A6NI28 A7KAX9 O00161 O00459 O15063 O15173 O15498 O43182 O60890 O75044 O75962 O94933 O94991 O95210 O96013 P02786 P04839 P05556 P10911 P11274 P13498 P14598 P19878 P24001 P27986 P29317 P42167 P42684 P43121 P49257 P50402 P51149 P52566 P52735 P55160 P60763 P60953 P78504 Q00587 Q01968 Q03135 Q07960 Q12979 Q13009 Q13017 Q13153 Q13177 Q13905 Q14126 Q14161 Q14739 Q15080 Q15758 Q15836 Q53QZ3 Q5T2T1 Q5T5U3 Q68EM7 Q6IAA8 Q6T4R5 Q6ZW31 Q7L576 Q86SJ2 Q86UR1 Q86Y07 Q8IZP0 Q8NFA2 Q8TAA9 Q8TCU6 Q8WUW1 Q8WUY9 Q8WWN8 Q8WZ64 Q92558 Q96AC1 Q96BY6 Q96RT1 Q9BSJ8 Q9C0H5 Q9H0H5 Q9H2K8 Q9HBY0 Q9NRY4 Q9NSV4 Q9NYB9 Q9UH65 Q9UHR4 Q9UNA1 Q9UQB8 Q9Y2A7 Q9Y2U8 Q9Y2X7 Q9Y5S8 Q9Y6W5	ABI1 ABI2 ABL2 ABLL ABR ALI1 AMIGO2 ARAP2 ARAP3 ARG ARGBPIA ARHGAP1 ARHGAP10 ARHGAP15 ARHGAP17 ARHGAP21 ARHGAP26 ARHGAP32 ARHGAP34 ARHGAP35 ARHGAP39 ARHGAP42 ARHGAP5 ARHGAP6 ARHGDIB ASCT2 BAIAP2 BAIAP2L1 BCR BCR1 BORG5 BRK1 C11orf59 C3orf10 CAV CAV1 CDC42 CDC42EP1 CDC42GAP CDHF5 CENTD1 CENTD3 CEP1 CYBA CYBB CYFIP1 D22S11 DBL DEPDC1B DG6 DIAP3 DIAPH3 DOCK10 DPK DSG2 ECK EDMD EMD EPHA2 ERBB2IP ERBIN ERGIC53 ESYT1 F5F8D FAM62A FERMT2 FNBP2 FNRB GARRE1 GDIA2 GDID4 GIT1 GIT2 GRAF GRAF3 GRB1 GRF1 GRF2 GRIT GRLF1 HEM1 HEM2 IL32 IRTKS ITGB1 JAG1 JAGL1 JIK KDS KIAA0068 KIAA0148 KIAA0269 KIAA0355 KIAA0456 KIAA0580 KIAA0587 KIAA0621 KIAA0640 KIAA0694 KIAA0712 KIAA0747 KIAA0848 KIAA0918 KIAA1142 KIAA1225 KIAA1415 KIAA1424 KIAA1478 KIAA1688 KIAA1722 KIND2 LAMTOR1 LAP2 LBR LEMD3 LMAN1 LRRC11 M7V1 MAN1 MAP3K18 MBC2 MCAM MCF2 MDF2 MGCRACGAP MIG2 MOX1 MOX2 MPP7 MSE55 MSK12 MUC18 NAP1 NCF1 NCF2 NCF4 NCKAP1 NCKAP1L NHS NK4 NOH1 NOX1 NOX2 NOX3 NOXA1 NOXA2 NOXO1 NOXO2 OCRL OCRL1 OPHN1 OPHN1L P190A P41NOX P51NOX P67PHOX PAK1 PAK2 PAK4 PDRO PGRMC2 PIK3R1 PIK3R2 PLEKHC1 PMBP PREX1 RAB7 RAB7A RAC3 RACGAP1 RAP1GN1 RAPGEF1 RDR RDRC RHOGAP1 RHOGAP5 RHOGAP6 RICH1 RICS SCAR1 SH3PXD1A SH3PXD4 SH3PXD5 SLC1A5 SLITRK3 SLITRK5 SNAP23 SRGAP2 SRGAP2A SSH3BP1 STA STB2 STBD1 SWAP70 SYB3 SYDE1 TAIF TAOK3 TFRC TIAM1 TMEM133 TMPO TRIO VAMP3 VANGL1 VAV2 VRK2 WASF1 WASF2 WAVE1 WAVE2 XTP8 YKT6 ZIZ3 p190ARHOGAP	Homo sapiens (human)
Formation of paraxial mesoderm	Bone morphogenetic protein 4 CREB-binding protein Catenin beta-1 Delta-like protein 1 Delta-like protein 3 Fibroblast growth factor receptor 1 Histone acetyltransferase KAT2A Histone acetyltransferase KAT2B Histone acetyltransferase p300 Lymphoid enhancer-binding factor 1 Mastermind-like domain-containing protein 1 Mastermind-like protein 1 Mastermind-like protein 2 Mastermind-like protein 3 Mesogenin-1 Neurogenic locus notch homolog protein 1 Noggin Protein Wnt-3a Recombining binding protein suppressor of hairless SNW domain-containing protein 1 T-box transcription factor T T-box transcription factor TBX6	A6NI15 O00548 O15178 O95947 P11362 P12644 P35222 P46531 P56704 Q06330 Q09472 Q13253 Q13495 Q13573 Q8IZL2 Q92585 Q92793 Q92830 Q92831 Q96JK9 Q9NYJ7 Q9UJU2	BFGFR BMP2B BMP4 CBP CEK CG1 CREBBP CTNNB CTNNB1 CXorf6 DLL1 DLL3 DVR4 EP300 FGFBR FGFR1 FLG FLT2 GCN5 GCN5L2 HBGFR IGKJRB IGKJRB1 KAT2A KAT2B KIAA0200 KIAA1816 KIAA1819 LEF1 MAML1 MAML2 MAML3 MAMLD1 MSGN1 NOG NOTCH1 P300 PCAF RBPJ RBPJK RBPSUH SKIIP SKIP SNW1 T TAN1 TBX6 TBXT WNT3A	Homo sapiens (human)
Somitogenesis	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe Catenin beta-1 Delta-like protein 1 Delta-like protein 3 Ephrin type-A receptor 4 Lymphoid enhancer-binding factor 1 Mesoderm posterior protein 2 Mesogenin-1 Neurogenic locus notch homolog protein 1 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein ripply2 Recombining binding protein suppressor of hairless T-box transcription factor TBX6 Transcription factor HES-7	A6NI15 O00231 O00232 O00233 O00487 O00548 O14818 O43242 O75832 O95947 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35222 P35998 P40306 P43686 P46531 P48556 P49720 P49721 P51665 P54764 P55036 P60896 P60900 P61289 P62191 P62195 P62333 Q06323 Q06330 Q0VG99 Q13200 Q15008 Q16401 Q5TAB7 Q8NES3 Q92530 Q99436 Q99460 Q9BYE0 Q9NYJ7 Q9UJU2 Q9UL46 Q9UNM6	BHLHB37 BHLHC6 C6orf159 C7orf76 CTNNB CTNNB1 DLL1 DLL3 DSS1 EPHA4 HC2 HC3 HC8 HC9 HEK8 HES7 HSPC IFI5111 IGKJRB IGKJRB1 KIAA0072 KIAA0107 LEF1 LFNG LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MESP2 MIP224 MOV34L MSGN1 MSS1 NOTCH1 NU PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSMF1 RBPJ RBPJK RBPSUH RING10 RING12 RIPPLY2 SCDO2 SEK SEM1 SHFDG1 SHFM1 SUG1 SUG2 TAN1 TBP1 TBP7 TBX6 TRAP2 TYRO1 X Y Y2 Z	Homo sapiens (human)
Amino acids regulate mTORC1	Cytosolic arginine sensor for mTORC1 subunit 1 Cytosolic arginine sensor for mTORC1 subunit 2 Folliculin-interacting protein 1 Folliculin-interacting protein 2 Folliculin GATOR1 complex protein DEPDC5 GATOR1 complex protein NPRL2 GATOR1 complex protein NPRL3 GATOR2 complex protein MIOS GATOR2 complex protein WDR24 GATOR2 complex protein WDR59 GTP-binding protein Rheb KICSTOR complex protein ITFG2 KICSTOR complex protein SZT2 KICSTOR complex protein kaptin KICSTOR subunit 2 Neutral amino acid transporter 9 Nucleoporin SEH1 Protein SEC13 homolog Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein A Ras-related GTP-binding protein B Ras-related GTP-binding protein C Ras-related GTP-binding protein D Regulatory-associated protein of mTOR S-adenosylmethionine sensor upstream of mTORC1 SH3 domain-binding protein 4 Serine/threonine-protein kinase mTOR Sestrin-1 Sestrin-2 Target of rapamycin complex subunit LST8 V-type proton ATPase 116 kDa subunit a 3 V-type proton ATPase 16 kDa proteolipid subunit c V-type proton ATPase 21 kDa proteolipid subunit c'' V-type proton ATPase catalytic subunit A V-type proton ATPase subunit B, brain isoform V-type proton ATPase subunit B, kidney isoform V-type proton ATPase subunit C 1 V-type proton ATPase subunit C 2 V-type proton ATPase subunit D V-type proton ATPase subunit E 1 V-type proton ATPase subunit E 2 V-type proton ATPase subunit F V-type proton ATPase subunit G 1 V-type proton ATPase subunit G 2 V-type proton ATPase subunit G 3 V-type proton ATPase subunit H V-type proton ATPase subunit d 1 V-type proton ATPase subunit d 2 V-type proton ATPase subunit e 1 V-type proton ATPase subunit e 2	A6NHX0 O15342 O43504 O75140 O75348 O95670 P15313 P21281 P21283 P27449 P36543 P38606 P42345 P55735 P58004 P61421 Q0VGL1 Q12980 Q13488 Q15382 Q16864 Q1RMZ1 Q5T011 Q5VZM2 Q6IAA8 Q6PJI9 Q7L523 Q8N122 Q8N8Y2 Q8NBW4 Q8NEY4 Q8NFG4 Q8NHE4 Q8TF40 Q8WTW4 Q8WTX7 Q969R8 Q96A05 Q96EE3 Q96LB4 Q96MD2 Q96S15 Q99437 Q9BVC4 Q9HB90 Q9NQL2 Q9NXC5 Q9P0V3 Q9P278 Q9UHA4 Q9UI12 Q9Y2Q5 Q9Y5K8 Q9Y664 Q9Y6P5	ATP6A1 ATP6B1 ATP6B2 ATP6C ATP6D ATP6E ATP6E1 ATP6E2 ATP6EL2 ATP6F ATP6G ATP6G1 ATP6G2 ATP6G3 ATP6H ATP6J ATP6L ATP6M ATP6N1C ATP6S14 ATP6V0A3 ATP6V0B ATP6V0C ATP6V0D1 ATP6V0D2 ATP6V0E ATP6V0E1 ATP6V0E2 ATP6V0E2L ATP6V1A ATP6V1A1 ATP6V1B1 ATP6V1B2 ATP6V1C1 ATP6V1C2 ATP6V1D ATP6V1E1 ATP6V1E2 ATP6V1EL2 ATP6V1F ATP6V1G1 ATP6V1G2 ATP6V1G3 ATP6V1H ATPL BHD BMT2 BOG25 C11orf59 C12orf66 C16orf21 C16orf35 C1orf84 C7orf32 C7orf59 C7orf60 CASTOR1 CASTOR2 CGTHBA D3S1231E DEPDC5 EHB10 FLCN FNIP1 FNIP2 FNIPL FRAP FRAP1 FRAP2 GATSL1 GATSL2 GATSL3 GBL HBXIP Hi95 ITFG2 KIAA0467 KIAA0645 KIAA1303 KIAA1450 KIAA1923 KIAA1961 KICS2 KPTN LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 LST8 MAP2K1IP1 MAPBPIP MAPKSP1 MAPO1 MARE MIOS MLST8 MTOR NG38 NPRL2 NPRL3 PA26 PDRO RAFT1 RAPT1 RAPTOR RHEB RHEB2 ROBLD3 RPTOR RRAGA RRAGB RRAGC RRAGD SAMTOR SEC13 SEC13A SEC13L SEC13L1 SEC13R SEH1 SEH1L SESN1 SESN2 SEST1 SEST2 SH3BP4 SLC38A9 SZT2 TCIRG1 TTP TUSC4 URLC11 VATB VATC VATD VATF VPATPD VPP2 VPP3 WDR24 WDR59 XIP	Homo sapiens (human)
Formation of tubulin folding intermediates by CCT/TriC	Putative tubulin-like protein alpha-4B T-complex protein 1 subunit alpha T-complex protein 1 subunit beta T-complex protein 1 subunit delta T-complex protein 1 subunit epsilon T-complex protein 1 subunit eta T-complex protein 1 subunit gamma T-complex protein 1 subunit theta T-complex protein 1 subunit zeta-2 T-complex protein 1 subunit zeta Tubulin alpha chain-like 3 Tubulin alpha-1A chain Tubulin alpha-1B chain Tubulin alpha-1C chain Tubulin alpha-3C chain Tubulin alpha-3D chain Tubulin alpha-3E chain Tubulin alpha-4A chain Tubulin alpha-8 chain Tubulin beta-1 chain Tubulin beta-2A chain Tubulin beta-2B chain Tubulin beta-3 chain Tubulin beta-4A chain Tubulin beta-4B chain Tubulin beta-6 chain	A6NHL2 P04350 P0DPH7 P0DPH8 P17987 P40227 P48643 P49368 P50990 P50991 P68363 P68366 P68371 P78371 Q13509 Q13885 Q6PEY2 Q71U36 Q92526 Q99832 Q9BQE3 Q9BUF5 Q9BVA1 Q9H4B7 Q9H853 Q9NY65	99D8.1 C21orf112 CCT1 CCT2 CCT3 CCT4 CCT5 CCT6 CCT6A CCT6B CCT7 CCT8 CCTA CCTB CCTD CCTE CCTG CCTH CCTQ CCTZ KIAA0002 KIAA0098 NIP7-1 SRB TCP1 TRIC5 TUBA1 TUBA1A TUBA1B TUBA1C TUBA2 TUBA3 TUBA3C TUBA3D TUBA3E TUBA4 TUBA4A TUBA4B TUBA6 TUBA8 TUBAL2 TUBAL3 TUBB1 TUBB2 TUBB2A TUBB2B TUBB2C TUBB3 TUBB4 TUBB4A TUBB4B TUBB5 TUBB6	Homo sapiens (human)
Post-chaperonin tubulin folding pathway	ADP-ribosylation factor-like protein 2 Putative tubulin-like protein alpha-4B Tubulin alpha chain-like 3 Tubulin alpha-1A chain Tubulin alpha-1B chain Tubulin alpha-1C chain Tubulin alpha-3C chain Tubulin alpha-3D chain Tubulin alpha-3E chain Tubulin alpha-4A chain Tubulin alpha-8 chain Tubulin beta-1 chain Tubulin beta-2A chain Tubulin beta-2B chain Tubulin beta-3 chain Tubulin beta-4A chain Tubulin beta-4B chain Tubulin beta-6 chain Tubulin-folding cofactor B Tubulin-specific chaperone A Tubulin-specific chaperone C Tubulin-specific chaperone D Tubulin-specific chaperone E	A6NHL2 O75347 P04350 P0DPH7 P0DPH8 P36404 P68363 P68366 P68371 Q13509 Q13885 Q15813 Q15814 Q6PEY2 Q71U36 Q99426 Q9BQE3 Q9BTW9 Q9BUF5 Q9BVA1 Q9H4B7 Q9H853 Q9NY65	ARL2 CG22 CKAP1 KIAA0988 SSD1 TBCA TBCB TBCC TBCD TBCE TFCD TUBA1 TUBA1A TUBA1B TUBA1C TUBA2 TUBA3 TUBA3C TUBA3D TUBA3E TUBA4 TUBA4A TUBA4B TUBA6 TUBA8 TUBAL2 TUBAL3 TUBB1 TUBB2 TUBB2A TUBB2B TUBB2C TUBB3 TUBB4 TUBB4A TUBB4B TUBB5 TUBB6	Homo sapiens (human)
Sealing of the nuclear envelope (NE) by ESCRT-III	Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4a Charged multivesicular body protein 4b Charged multivesicular body protein 4c Charged multivesicular body protein 6 Charged multivesicular body protein 7 Coiled-coil and C2 domain-containing protein 1B IST1 homolog LEM domain-containing protein 2 Putative tubulin-like protein alpha-4B Spastin Tubulin alpha chain-like 3 Tubulin alpha-1A chain Tubulin alpha-1B chain Tubulin alpha-1C chain Tubulin alpha-3C chain Tubulin alpha-3D chain Tubulin alpha-3E chain Tubulin alpha-4A chain Tubulin alpha-8 chain Tubulin beta 8B Tubulin beta-1 chain Tubulin beta-2A chain Tubulin beta-2B chain Tubulin beta-3 chain Tubulin beta-4A chain Tubulin beta-4B chain Tubulin beta-6 chain Tubulin beta-8 chain Vacuolar protein sorting-associated protein 4A	A6NHL2 A6NNZ2 O43633 P04350 P0DPH7 P0DPH8 P53990 P68363 P68366 P68371 Q13509 Q13885 Q3ZCM7 Q5T0F9 Q6PEY2 Q71U36 Q8NC56 Q8WUX9 Q96CF2 Q96FZ7 Q9BQE3 Q9BUF5 Q9BVA1 Q9BY43 Q9H444 Q9H4B7 Q9H853 Q9NY65 Q9UBP0 Q9UN37 Q9UQN3 Q9Y3E7	ADPSP BC2 C14orf123 C20orf178 CC2D1B CGI149 CHMP2 CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP6 CHMP7 FSP2 IST1 KIAA0174 KIAA1083 KIAA1836 LEMD2 LGD1 NEDF SHAX1 SHAX2 SHAX3 SPAST SPG4 TUBA1 TUBA1A TUBA1B TUBA1C TUBA2 TUBA3 TUBA3C TUBA3D TUBA3E TUBA4 TUBA4A TUBA4B TUBA6 TUBA8 TUBAL2 TUBAL3 TUBB1 TUBB2 TUBB2A TUBB2B TUBB2C TUBB3 TUBB4 TUBB4A TUBB4B TUBB5 TUBB6 TUBB8 TUBB8B VPS20 VPS24 VPS4 VPS4A	Homo sapiens (human)
Degradation of the extracellular matrix	72 kDa type IV collagenase A disintegrin and metalloproteinase with thrombospondin motifs 16 A disintegrin and metalloproteinase with thrombospondin motifs 18 A disintegrin and metalloproteinase with thrombospondin motifs 1 A disintegrin and metalloproteinase with thrombospondin motifs 4 A disintegrin and metalloproteinase with thrombospondin motifs 5 A disintegrin and metalloproteinase with thrombospondin motifs 8 A disintegrin and metalloproteinase with thrombospondin motifs 9 Aggrecan core protein Alpha-2-macroglobulin Basement membrane-specific heparan sulfate proteoglycan core protein Basigin Bone morphogenetic protein 1 Brevican core protein CD44 antigen Cadherin-1 Calpain small subunit 1 Calpain small subunit 2 Calpain-1 catalytic subunit Calpain-10 Calpain-11 Calpain-12 Calpain-13 Calpain-14 Calpain-15 Calpain-2 catalytic subunit Calpain-3 Calpain-5 Calpain-6 Calpain-7 Calpain-8 Calpain-9 Calpastatin Caspase-3 Cathepsin G Cathepsin K Cathepsin L2 Cathepsin S Collagenase 3 Decorin Disintegrin and metalloproteinase domain-containing protein 10 Disintegrin and metalloproteinase domain-containing protein 15 Disintegrin and metalloproteinase domain-containing protein 8 Interstitial collagenase Kallikrein-7 Laminin subunit alpha-3 Laminin subunit alpha-5 Laminin subunit beta-1 Laminin subunit beta-3 Laminin subunit gamma-1 Laminin subunit gamma-2 Macrophage metalloelastase Matrilysin Matrix metalloproteinase-14 Matrix metalloproteinase-15 Matrix metalloproteinase-19 Matrix metalloproteinase-20 Matrix metalloproteinase-9 Neutrophil collagenase Neutrophil elastase Nicastrin Nidogen-1 Opticin Osteopontin Plasminogen Presenilin-1 Procathepsin L Serine protease HTRA1 Signal peptide, CUB and EGF-like domain-containing protein 1 Signal peptide, CUB and EGF-like domain-containing protein 3 Stromelysin-1 Stromelysin-2 Stromelysin-3 Tolloid-like protein 1 Tolloid-like protein 2 Transmembrane protease serine 6	A6NHC0 A8MX76 O14672 O14815 O15230 O15484 O43897 O60882 O60911 O75173 O75808 P00747 P01023 P03956 P04632 P07384 P07585 P07711 P07942 P08246 P08253 P08254 P08311 P09237 P09238 P10451 P11047 P12830 P13497 P14543 P14780 P16070 P16112 P17655 P20807 P20810 P22894 P24347 P25774 P35613 P39900 P42574 P43235 P45452 P49768 P49862 P50281 P51511 P78325 P98160 Q13444 Q13751 Q13753 Q16787 Q6MZZ7 Q6ZSI9 Q8IU80 Q8IWY4 Q8IX30 Q8TE57 Q8TE60 Q92542 Q92743 Q96GW7 Q96L46 Q99542 Q9HC96 Q9P2N4 Q9UBM4 Q9UHI8 Q9UMQ6 Q9UNA0 Q9UP79 Q9Y6L7 Q9Y6Q1 Q9Y6W3	A2M ACAN AD3 ADAM10 ADAM15 ADAM8 ADAMTS1 ADAMTS11 ADAMTS16 ADAMTS18 ADAMTS21 ADAMTS4 ADAMTS5 ADAMTS8 ADAMTS9 ADMP2 AGC1 BCAN BEHAB BMP1 BNSP BSG CALPM CANP3 CANPL1 CANPL2 CANPL3 CANPX CAPN1 CAPN10 CAPN11 CAPN12 CAPN13 CAPN14 CAPN15 CAPN2 CAPN3 CAPN4 CAPN5 CAPN6 CAPN7 CAPN8 CAPN9 CAPNS CAPNS1 CAPNS2 CASP3 CAST CATL2 CD44 CDH1 CDHE CEGF3 CLG CLG1 CLG4A CLG4B CPAMD5 CPP32 CSPG1 CSPG7 CTSG CTSK CTSL CTSL1 CTSL2 CTSO CTSO2 CTSS CTSU CTSV DCN ELA2 ELANE HME HSPG2 HTRA HTRA1 KIAA0253 KIAA0533 KIAA0688 KIAA0932 KIAA1312 KIAA1346 KIAA1845 KIAA1907 KIAA2029 KLK7 KUZ LAMA3 LAMA5 LAMB1 LAMB2 LAMB2T LAMB3 LAMC1 LAMC2 LAMNA LAMNB1 LAMNB2 LHR MADM MDC15 MDU2 MDU3 METH1 METH2 MIC4 MMP1 MMP10 MMP11 MMP12 MMP13 MMP14 MMP15 MMP18 MMP19 MMP2 MMP20 MMP3 MMP7 MMP8 MMP9 MPSL1 MS2 MSK16 NCL1 NCL2 NCL3 NCL4 NCSTN NID NID1 OPN OPT OPTC PALBH PCOLC PLG PRSS11 PRSS6 PS1 PSEN1 PSNL1 PUMP1 RASI SCCE SCUBE1 SCUBE3 SLRR1B SOLH SPP1 STMY1 STMY2 STMY3 TLL TLL1 TLL2 TMPRSS6 UVO	Homo sapiens (human)
Serine biosynthesis	D-3-phosphoglycerate dehydrogenase Phosphoserine aminotransferase Phosphoserine phosphatase Serine incorporator 1 Serine incorporator 2 Serine incorporator 3 Serine incorporator 4 Serine incorporator 5 Serine racemase	A6NH21 O43175 P78330 Q13530 Q86VE9 Q96SA4 Q9GZT4 Q9NRX5 Q9Y617	C5orf12 DIFF33 KIAA1253 PGDH3 PHGDH PSA PSAT1 PSPH SERINC1 SERINC2 SERINC3 SERINC4 SERINC5 SRR TDE1 TDE1L TDE2 TDE2L	Homo sapiens (human)
APAP ADME	ATP-binding cassette sub-family C member 2 ATP-binding cassette sub-family C member 3 ATP-binding cassette sub-family C member 4 ATP-binding cassette sub-family C member 5 Aminoacylase-1 Arylamine N-acetyltransferase 1 Arylamine N-acetyltransferase 2 Broad substrate specificity ATP-binding cassette transporter ABCG2 Cytochrome P450 2E1 Cytosolic non-specific dipeptidase Glutathione S-transferase Mu 1 Glutathione S-transferase P Glutathione S-transferase theta-1 Glutathione hydrolase 1 proenzyme Glutathione hydrolase 5 proenzyme Glutathione hydrolase 6 Glutathione hydrolase 7 Multidrug resistance-associated protein 1 Putative glutathione hydrolase 3 proenzyme Sulfotransferase 1A1 Sulfotransferase 1A3 Sulfotransferase 1A4 Sulfotransferase 1C4 Sulfotransferase 1E1 Sulfotransferase 2A1 UDP-glucuronosyltransferase 1-6 UDP-glucuronosyltransferase 1A10 UDP-glucuronosyltransferase 1A1 UDP-glucuronosyltransferase 1A9 UDP-glucuronosyltransferase 2B15	A6NGU5 O15438 O15439 O15440 O60656 O75897 P05181 P09211 P09488 P0DMM9 P0DMN0 P11245 P18440 P19224 P19440 P22309 P30711 P33527 P36269 P49888 P50225 P54855 Q03154 Q06520 Q6P531 Q92887 Q96KP4 Q9HAW8 Q9UJ14 Q9UNQ0	AAC1 AAC2 ABCC1 ABCC2 ABCC3 ABCC4 ABCC5 ABCG2 ABCP ACY1 BCRP BCRP1 CMOAT CMOAT1 CMOAT2 CMRP CN2 CNDP2 CPGL CYP2E CYP2E1 FAEES3 GGT GGT1 GGT3 GGT3P GGT5 GGT6 GGT7 GGTL3 GGTL5 GGTLA1 GNT1 GST1 GST3 GSTM1 GSTP1 GSTT1 HEL-S-13 HST MLP2 MOATB MRP MRP1 MRP2 MRP3 MRP4 MRP5 MXR NAT1 NAT2 PEPA STD STE STM STP STP1 SULT1A1 SULT1A3 SULT1A4 SULT1C2 SULT1C4 SULT1E1 SULT2A1 UGT1 UGT1A1 UGT1A10 UGT1A6 UGT1A9 UGT2B15 UGT2B8	Homo sapiens (human)
Aflatoxin activation and detoxification	Aflatoxin B1 aldehyde reductase member 2 Aflatoxin B1 aldehyde reductase member 3 Aflatoxin B1 aldehyde reductase member 4 Aminoacylase-1 Cytochrome P450 1A2 Cytochrome P450 2A13 Cytochrome P450 3A4 Cytochrome P450 3A5 Dipeptidase 1 Dipeptidase 2 Dipeptidase 3 Glutathione S-transferase 3, mitochondrial Glutathione hydrolase 1 proenzyme Glutathione hydrolase 5 proenzyme Glutathione hydrolase 6 Glutathione hydrolase 7 Microsomal glutathione S-transferase 1 Microsomal glutathione S-transferase 2 N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) Putative glutathione hydrolase 3 proenzyme	A6NGU5 O14880 O43488 O95154 P05177 P08684 P10620 P16444 P19440 P20815 P36269 Q03154 Q16696 Q6P531 Q8NHP1 Q96HD9 Q99735 Q9H4A9 Q9H4B8 Q9UJ14	ACY1 ACY3 AFAR AFAR1 AFAR2 AFAR3 AKR7 AKR7A2 AKR7A3 AKR7A4 AKR7L ASPA2 CYP1A2 CYP2A13 CYP3A3 CYP3A4 CYP3A5 DPEP1 DPEP2 DPEP3 GGT GGT1 GGT3 GGT3P GGT5 GGT6 GGT7 GGTL3 GGTL5 GGTLA1 GST12 GST2 MDP MGST MGST1 MGST2 MGST3 RDP	Homo sapiens (human)
Glutathione synthesis and recycling	5-oxoprolinase Cytosolic non-specific dipeptidase Gamma-glutamylcyclotransferase Glutamate--cysteine ligase catalytic subunit Glutamate--cysteine ligase regulatory subunit Glutathione hydrolase 1 proenzyme Glutathione hydrolase 5 proenzyme Glutathione hydrolase 6 Glutathione hydrolase 7 Glutathione synthetase Glutathione-specific gamma-glutamylcyclotransferase 1 Glutathione-specific gamma-glutamylcyclotransferase 2 Putative glutathione hydrolase 3 proenzyme	A6NGU5 O14841 O75223 P19440 P36269 P48506 P48507 P48637 Q6P531 Q8WUX2 Q96KP4 Q9BUX1 Q9UJ14	BOTCH C7orf24 CHAC1 CHAC2 CN2 CNDP2 CPGL CRF21 GCLC GCLM GGCT GGT GGT1 GGT3 GGT3P GGT5 GGT6 GGT7 GGTL3 GGTL5 GGTLA1 GLCL GLCLC GLCLR GSS HEL-S-13 OPLAH PEPA	Homo sapiens (human)
RHO GTPases Activate WASPs and WAVEs	Abl interactor 1 Abl interactor 2 Actin nucleation-promoting factor WAS Actin nucleation-promoting factor WASL Actin, cytoplasmic 1 Actin, cytoplasmic 2 Actin-binding protein WASF1 Actin-binding protein WASF2 Actin-binding protein WASF3 Actin-related protein 2/3 complex subunit 1A Actin-related protein 2/3 complex subunit 1B Actin-related protein 2/3 complex subunit 2 Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2 Actin-related protein 3 BAR/IMD domain-containing adapter protein 2 Cell division control protein 42 homolog Cytoplasmic FMR1-interacting protein 1 Cytoplasmic FMR1-interacting protein 2 Focal adhesion kinase 1 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 NCK-interacting protein with SH3 domain Nck-associated protein 1-like Nck-associated protein 1 Protein BRICK1 Ras-related C3 botulinum toxin substrate 1 SH2/SH3 adapter protein NCK1 Tyrosine-protein kinase ABL1 Tyrosine-protein kinase BTK WAS/WASL-interacting protein family member 1 WAS/WASL-interacting protein family member 2 WAS/WASL-interacting protein family member 3	A6NGB9 O00401 O15143 O15144 O15145 O15511 O43516 P00519 P16333 P27361 P28482 P42768 P55160 P59998 P60709 P60953 P61158 P61160 P63000 P63261 Q05397 Q06187 Q7L576 Q8IZP0 Q8TF74 Q8WUW1 Q92558 Q92747 Q96F07 Q9NYB9 Q9NZQ3 Q9UPY6 Q9UQB8 Q9Y2A7 Q9Y6W5	ABI1 ABI2 ABL ABL1 ACTB ACTG ACTG1 ACTR2 ACTR3 AF3P21 AGMX1 ARC16 ARC20 ARC21 ARC34 ARC41 ARGBPIA ARP2 ARP3 ARPC1A ARPC1B ARPC2 ARPC3 ARPC4 ARPC5 ATK BAIAP2 BPK BRK1 BTK C3orf10 CDC42 CR16 CYFIP1 CYFIP2 ERK1 ERK2 FAK FAK1 HEM1 HEM2 IMD2 JTK7 KIAA0068 KIAA0269 KIAA0587 KIAA0900 KIAA1168 MAPK1 MAPK3 NAP1 NCK NCK1 NCKAP1 NCKAP1L NCKIPSD PIR121 PRKM1 PRKM2 PRKM3 PTK2 RAC1 SCAR1 SCAR3 SOP2L SPIN90 SSH3BP1 TC25 WAS WASF1 WASF2 WASF3 WASL WASPIP WAVE1 WAVE2 WAVE3 WICH WIP WIPF1 WIPF2 WIPF3 WIRE	Homo sapiens (human)
Maturation of TCA enzymes and regulation of TCA cycle	Acetyl-CoA acetyltransferase, mitochondrial Aconitate hydratase, mitochondrial Citrate synthase, mitochondrial Citrate synthase-lysine N-methyltransferase CSKMT, mitochondrial Frataxin, mitochondrial Iron-sulfur cluster assembly 1 homolog, mitochondrial Iron-sulfur cluster assembly 2 homolog, mitochondrial Isocitrate dehydrogenase [NADP], mitochondrial LYR motif-containing protein 4 NAD-dependent protein deacetylase sirtuin-3, mitochondrial Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Succinate dehydrogenase assembly factor 1, mitochondrial Succinate dehydrogenase assembly factor 2, mitochondrial Succinate dehydrogenase assembly factor 3, mitochondrial Succinate dehydrogenase assembly factor 4, mitochondrial Succinate dehydrogenase cytochrome b560 subunit, mitochondrial	A6NFY7 A8MUP2 O14521 O75390 P21912 P24752 P31040 P48735 Q16595 Q5VUM1 Q86U28 Q99643 Q99798 Q9BUE6 Q9HD34 Q9NRP4 Q9NTG7 Q9NX18	ACAT ACAT1 ACN9 ACO2 C11orf79 C6orf149 C6orf57 CS CSKMT CYB560 FRDA FXN HBLD1 HBLD2 IDH2 ISCA1 ISCA2 ISD11 LYRM4 LYRM8 MAT METTL12 PGL2 SDH SDH1 SDH2 SDH3 SDH4 SDH5 SDHA SDHAF1 SDHAF2 SDHAF3 SDHAF4 SDHB SDHC SDHD SDHF SIR2L3 SIRT3 X25	Homo sapiens (human)
Sphingolipid de novo biosynthesis	3-ketodihydrosphingosine reductase Broad substrate specificity ATP-binding cassette transporter ABCG2 Casein kinase I isoform gamma-2 Ceramide synthase 1 Ceramide synthase 2 Ceramide synthase 3 Ceramide synthase 4 Ceramide synthase 5 Ceramide synthase 6 Cytochrome b5 type B Fatty acid 2-hydroxylase Multidrug resistance-associated protein 1 ORM1-like protein 1 ORM1-like protein 2 ORM1-like protein 3 Oxysterol-binding protein 1 Phosphatidylcholine Phosphatidylcholine Protein phosphatase 1L Serine palmitoyltransferase 1 Serine palmitoyltransferase 2 Serine palmitoyltransferase 3 Serine palmitoyltransferase small subunit A Serine palmitoyltransferase small subunit B Serine/threonine-protein kinase D1 Serine/threonine-protein kinase D2 Serine/threonine-protein kinase D3 Sphingolipid delta(4)-desaturase DES1 Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 Sphingomyelin synthase-related protein 1 Sphingosine kinase 1 Sphingosine kinase 2 Sphingosine-1-phosphate transporter MFSD2B Sphingosine-1-phosphate transporter SPNS2 Vesicle-associated membrane protein-associated protein A Vesicle-associated membrane protein-associated protein B/C	A6NFX1 O15121 O15269 O15270 O43169 O94806 O95292 P22059 P27544 P33527 P78368 Q06136 Q15139 Q53FV1 Q5SGD2 Q6QHC5 Q6ZMG9 Q7L5A8 Q86VZ5 Q8IU89 Q8IVW8 Q8N138 Q8N5B7 Q8NFR3 Q8NHU3 Q969W0 Q96G23 Q96LT4 Q9BZL6 Q9HA82 Q9NRA0 Q9NUV7 Q9NYA1 Q9P0L0 Q9P0S3 Q9UNQ0	ABCC1 ABCG2 ABCP ADMP BCRP BCRP1 C14orf147 C14orf66 C20orf38 C3orf57 CERS1 CERS2 CERS3 CERS4 CERS5 CERS6 CK1G2 CSNK1G2 CYB5B CYB5M DEGS1 DEGS2 DES1 EPK2 FA2H FAAH FAXDC1 FVT1 KDSR KIAA0526 LAG1 LASS1 LASS2 LASS3 LASS4 LASS5 LASS6 LCB1 LCB2 MFSD2B MLD MOB MRP MRP1 MXR OMB5 ORMDL1 ORMDL2 ORMDL3 OSBP OSBP1 PKD PKD1 PKD2 PP2CE PPM1L PRKCM PRKCN PRKD1 PRKD2 PRKD3 SAMD8 SDR35C1 SGMS1 SGMS2 SK1 SK2 SMS1 SMS2 SPHK SPHK1 SPHK2 SPK SPNS2 SPTLC1 SPTLC2 SPTLC2L SPTLC3 SPTSSA SPTSSB SSSPTA SSSPTB TMEM23 TMSG1 UOG1 VAP33 VAPA VAPB	Homo sapiens (human)
NPAS4 regulates expression of target genes	Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Basic helix-loop-helix ARNT-like protein 1 Brain-derived neurotrophic factor CREB-binding protein Cyclin-dependent kinase 5 activator 1 Cyclin-dependent kinase 5 E3 ubiquitin-protein ligase Mdm2 Exportin-1 GTP-binding protein GEM IQ motif and SEC7 domain-containing protein 3 Insulin Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Neuronal PAS domain-containing protein 4 Nicotinamide phosphoribosyltransferase Protein c-Fos Proto-oncogene tyrosine-protein kinase receptor Ret RNA binding protein fox-1 homolog 3 Serine/threonine-protein kinase PLK2 Synaptotagmin-10	A6NFN3 O00327 O14980 P01100 P01308 P07949 P23560 P27361 P27540 P28482 P43490 P55040 Q00535 Q00987 Q15078 Q6XYQ8 Q8IUM7 Q92793 Q9HBZ2 Q9NYY3 Q9UPP2	ARNT ARNT2 ARNTL BDNF BHLHE1 BHLHE2 BHLHE5 BHLHE79 BMAL1 CBP CDHF12 CDHR16 CDK5 CDK5R CDK5R1 CDKN5 CREBBP CRM1 ERK1 ERK2 FOS G0S7 GEM INS IQSEC3 KIAA0307 KIAA1110 KIR MAPK1 MAPK3 MDM2 MOP3 NAMPT NCK5A NPAS4 NXF PASD10 PASD3 PBEF PBEF1 PLK2 PRKM1 PRKM2 PRKM3 PSSALRE PTC RBFOX3 RET SNK SYT10 XPO1	Homo sapiens (human)
Triglyceride catabolism	1-acylglycerol-3-phosphate O-acyltransferase ABHD5 Caveolin-1 Fatty acid-binding protein 12 Fatty acid-binding protein 5 Fatty acid-binding protein 9 Fatty acid-binding protein, adipocyte Fatty acid-binding protein, brain Fatty acid-binding protein, heart Fatty acid-binding protein, intestinal Fatty acid-binding protein, liver Gastrotropin Glycerol-3-phosphate dehydrogenase, mitochondrial Hormone-sensitive lipase Monoglyceride lipase Patatin-like phospholipase domain-containing protein 4 Patatin-like phospholipase domain-containing protein 5 Perilipin-1 Perilipin-3 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Serine/threonine-protein phosphatase PP1-beta catalytic subunit Serine/threonine-protein phosphatase PP1-gamma catalytic subunit cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	A6NFH5 O15540 O60240 O60664 P05413 P07148 P12104 P15090 P17612 P22612 P22694 P36873 P41247 P43304 P51161 P62136 P62140 Q01469 Q03135 Q05469 Q0Z7S8 Q7Z6Z6 Q8WTS1 Q99685	ABHD5 BLBP CAV CAV1 DXS1283E FABP1 FABP11 FABP12 FABP2 FABP3 FABP4 FABP5 FABP6 FABP7 FABP9 FABPB FABPI FABPL GPD2 GS2 GS2L ILBP ILLBP LIPE M6PRBP1 MDGI MGLL MRG NCIE2 PERI PKACA PLIN PLIN1 PLIN3 PNPLA4 PNPLA5 PPP1A PPP1CA PPP1CB PPP1CC PRKACA PRKACB PRKACG TIP47	Homo sapiens (human)
Protein hydroxylation	2-oxoglutarate and iron-dependent oxygenase JMJD4 Aspartyl/asparaginyl beta-hydroxylase Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 Bifunctional peptidase and arginyl-hydroxylase JMJD5 Coagulation factor IX Developmentally-regulated GTP-binding protein 1 Developmentally-regulated GTP-binding protein 2 Eukaryotic peptide chain release factor subunit 1 Large ribosomal subunit protein uL15 Large ribosomal subunit protein uL2 Prolyl 3-hydroxylase OGFOD1 RCC1 domain-containing protein 1 RWD domain-containing protein 1 Ribosomal oxygenase 1 Ribosomal oxygenase 2 Small ribosomal subunit protein eS6 Small ribosomal subunit protein uS12 Splicing factor U2AF 65 kDa subunit Zinc finger CCCH domain-containing protein 15	A6NED2 P00740 P0C870 P26368 P46776 P55039 P62266 P62495 P62753 P62917 Q12797 Q6NYC1 Q8IUF8 Q8N371 Q8N543 Q8WU90 Q9H446 Q9H6W3 Q9H9V9 Q9Y295	ASPH BAH C14orf169 DFRP1 DFRP2 DRG1 DRG2 ERF1 ETF1 F9 JMJD4 JMJD5 JMJD6 JMJD7 KDM8 KIAA0585 KIAA1612 LEREPO4 MAPJD MDIG MINA MINA53 NEDD3 NO52 NO66 OGFOD1 PSR PTDSR RCCD1 RF1 RIOX1 RIOX2 RPL27A RPL8 RPS23 RPS6 RWDD1 SUP45L1 TPA1 U2AF2 U2AF65 ZC3H15	Homo sapiens (human)
Glycolysis	ADP-dependent glucokinase ATP-dependent 6-phosphofructokinase, liver type ATP-dependent 6-phosphofructokinase, muscle type ATP-dependent 6-phosphofructokinase, platelet type Alpha-enolase Beta-enolase Bisphosphoglycerate mutase Enolase 4 Fructose-bisphosphate aldolase A Fructose-bisphosphate aldolase B Fructose-bisphosphate aldolase C Gamma-enolase Glucosamine-6-phosphate isomerase 1 Glucosamine-6-phosphate isomerase 2 Glucose 1,6-bisphosphate synthase Glucose-6-phosphate isomerase Glyceraldehyde-3-phosphate dehydrogenase, testis-specific Glyceraldehyde-3-phosphate dehydrogenase Glycerol-3-phosphate phosphatase Hexokinase HKDC1 Hexokinase-1 Hexokinase-2 Hexokinase-3 Hexokinase-4 Phosphoglycerate kinase 1 Phosphoglycerate kinase 2 Phosphoglycerate mutase 1 Phosphoglycerate mutase 2 Triosephosphate isomerase	A6NDG6 A6NNW6 O14556 P00558 P04075 P04406 P05062 P06733 P06744 P07205 P07738 P08237 P09104 P09972 P13929 P15259 P17858 P18669 P19367 P35557 P46926 P52789 P52790 P60174 Q01813 Q2TB90 Q6PCE3 Q8TDQ7 Q9BRR6	ADPGK ALDA ALDB ALDC ALDOA ALDOB ALDOC BM32A BPGM C10orf134 ENO1 ENO1L1 ENO2 ENO3 ENO4 GAPD GAPD2 GAPDH GAPDH2 GAPDHS GAPDS GCK GNP2 GNPDA1 GNPDA2 GNPI GPI HK1 HK2 HK3 HKDC1 HLN KIAA0060 MBPB1 MPB1 PFKF PFKL PFKM PFKP PFKX PGAM1 PGAM2 PGAMA PGAMM PGK1 PGK2 PGKA PGKB PGM2L1 PGP TPI TPI1	Homo sapiens (human)	G58161NS

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