GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **376 - 400** of **2090** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol
Synthesis of PIPs at the plasma membrane	ADP-ribosylation factor 1 Cytoplasmic tyrosine-protein kinase BMX Inositol polyphosphate 4-phosphatase type II Inositol polyphosphate 5-phosphatase K Inositol polyphosphate 5-phosphatase OCRL Inositol polyphosphate-4-phosphatase type I A Myotubularin-related protein 13 Myotubularin-related protein 14 Myotubularin-related protein 1 Myotubularin-related protein 2 Myotubularin-related protein 3 Myotubularin-related protein 6 Myotubularin-related protein 8 Myotubularin-related protein 9 Myotubularin Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A Phosphatidylinositol 4-kinase type 2-alpha Phosphatidylinositol 4-kinase type 2-beta Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha Phosphatidylinositol 4-phosphate 5-kinase type-1 beta Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha Phosphatidylinositol 5-phosphate 4-kinase type-2 beta Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma Phosphoinositide 3-kinase regulatory subunit 5 Phosphoinositide 3-kinase regulatory subunit 6 Pleckstrin homology domain-containing family A member 1 Pleckstrin homology domain-containing family A member 2 Pleckstrin homology domain-containing family A member 3 Pleckstrin homology domain-containing family A member 4 Pleckstrin homology domain-containing family A member 5 Pleckstrin homology domain-containing family A member 6 Pleckstrin homology domain-containing family A member 8 RUN and FYVE domain-containing protein 1 Ras-related protein Rab-14 Ras-related protein Rab-4A Ras-related protein Rab-5A Synaptojanin-1 Synaptojanin-2 Tyrosine-protein phosphatase non-receptor type 13	O00329 O00443 O00459 O00750 O14986 O15056 O15327 O15357 O43426 O60331 O75747 P20338 P20339 P27986 P42336 P42338 P48426 P48736 P51813 P60484 P61106 P78356 P84077 Q01968 Q12923 Q13496 Q13613 Q13614 Q13615 Q15735 Q5UE93 Q86WG5 Q8NCE2 Q8TBX8 Q8TCG2 Q8WYR1 Q92569 Q92835 Q96EF0 Q96JA3 Q96PE3 Q96QG7 Q96T51 Q99755 Q9BT40 Q9BTU6 Q9H4M7 Q9HAU0 Q9HB19 Q9HB20 Q9HB21 Q9Y217 Q9Y2H5	ARF1 BMX C17orf38 C3orf29 C8orf9 CG2 CMT4B2 FAPP1 FAPP2 GRB1 INPP4A INPP4B INPP5D INPP5J INPP5K INPPL1 KIAA0348 KIAA0371 KIAA0589 KIAA0910 KIAA0969 KIAA1073 KIAA1686 KIAA1766 MMAC1 MTM1 MTMR1 MTMR13 MTMR14 MTMR2 MTMR3 MTMR6 MTMR8 MTMR9 OCRL OCRL1 PEPP1 PEPP2 PEPP3 PI4K2A PI4K2B PI5P4KA PIB5PA PIK3C1 PIK3C2A PIK3C2B PIK3C2G PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PIK3R6 PIP4K2A PIP4K2B PIP4K2C PIP5K1A PIP5K1B PIP5K1C PIP5K2 PIP5K2A PIP5K2B PIP5K2C PIPP PLEKHA1 PLEKHA2 PLEKHA3 PLEKHA4 PLEKHA5 PLEKHA6 PLEKHA8 PNP1 PPS PTEN PTP1E PTPL1 PTPN13 RAB14 RAB4 RAB4A RAB5 RAB5A RABIP4 RUFY1 SBF2 SHIP SHIP1 SHIP2 SKIP STM7 SYNJ1 SYNJ2 TAPP1 TAPP2 TEP1 ZFYVE10 ZFYVE12
RET signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Artemin Docking protein 1 Docking protein 2 Docking protein 4 Docking protein 5 Docking protein 6 Fibroblast growth factor receptor substrate 2 GDNF family receptor alpha-1 GDNF family receptor alpha-2 GDNF family receptor alpha-3 GDNF family receptor alpha-4 GRB2-associated-binding protein 1 GRB2-associated-binding protein 2 Glial cell line-derived neurotrophic factor Growth factor receptor-bound protein 10 Growth factor receptor-bound protein 7 Insulin receptor substrate 2 Mitogen-activated protein kinase 7 Neurturin PDZ and LIM domain protein 7 Persephin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Protein kinase C alpha type Proto-oncogene tyrosine-protein kinase receptor Ret Rap1 GTPase-activating protein 1 SH3 and multiple ankyrin repeat domains protein 3 SHC-transforming protein 1 SHC-transforming protein 3 Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	O00329 O00451 O00459 O60496 O60542 O60609 P07949 P17252 P17612 P19174 P22612 P22694 P27986 P29353 P39905 P42336 P42338 P47736 P56159 Q06124 Q07889 Q13164 Q13322 Q13480 Q14451 Q5T4W7 Q6PKX4 Q8TEW6 Q8WU20 Q92529 Q92569 Q99704 Q99748 Q9BYB0 Q9GZZ7 Q9NR12 Q9P104 Q9UQC2 Q9Y4H2	ARTN BMK1 C20orf180 CDHF12 CDHR16 DOK1 DOK2 DOK4 DOK5 DOK5L DOK6 ENIGMA ERK5 EVN FRS2 GAB1 GAB2 GDNF GDNFRA GDNFRB GFRA1 GFRA2 GFRA3 GFRA4 GRB1 GRB10 GRB7 GRBIR IRS2 KIAA0207 KIAA0474 KIAA0571 KIAA1650 MAPK7 NRTN NSHC PDLIM7 PIK3C1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PKACA PKCA PLC1 PLCG1 PRKACA PRKACB PRKACG PRKCA PRKM7 PROSAP2 PSAP2 PSPN PTC PTP2C PTPN11 RAP1GA1 RAP1GAP RET RETL1 RETL2 SHANK3 SHC SHC1 SHC3 SHCA SHCC SHPTP2 SOS1 TRNR1 TRNR2
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Amphiregulin B-lymphocyte antigen CD19 Beta-klotho Epidermal growth factor receptor Epigen Estrogen receptor beta Estrogen receptor Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 19 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fms-related tyrosine kinase 3 ligand GRB2-associated-binding protein 1 GRB2-associated-binding protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor Insulin Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-like 1 Interleukin-33 Mast/stem cell growth factor receptor Kit Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Myeloid differentiation primary response protein MyD88 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha Phosphatidylinositol 4-phosphate 5-kinase type-1 beta Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha Phosphatidylinositol 5-phosphate 4-kinase type-2 beta Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma Phosphoinositide 3-kinase adapter protein 1 Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit B Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase Src Proto-oncogene vav Protransforming growth factor alpha RAC-alpha serine/threonine-protein kinase Radiation-inducible immediate-early gene IEX-1 Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 2 Receptor tyrosine-protein kinase erbB-2 Receptor-type tyrosine-protein kinase FLT3 Rho-related GTP-binding protein RhoG Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Striatin T-cell receptor-associated transmembrane adapter 1 T-cell-specific surface glycoprotein CD28 T-lymphocyte activation antigen CD80 T-lymphocyte activation antigen CD86 TNF receptor-associated factor 6 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lck Tyrosine-protein phosphatase non-receptor type 11	O00329 O00459 O14511 O14944 O14986 O15520 O43320 O43815 O60331 O76093 O95750 O95760 P00533 P01127 P01133 P01135 P01308 P03372 P04626 P05230 P06213 P06239 P06241 P08581 P08620 P09038 P09619 P10721 P10747 P10767 P11487 P12931 P14210 P15153 P15391 P15498 P15514 P16234 P21781 P22455 P27361 P27986 P28482 P30153 P30154 P31371 P31749 P33681 P35070 P35568 P36888 P42081 P42336 P42338 P46695 P48426 P49771 P51617 P56975 P62714 P63000 P67775 P78356 P84095 Q01638 Q02297 Q06124 Q13362 Q13480 Q14738 Q15172 Q15173 Q16537 Q6PIZ9 Q6UW88 Q6ZUJ8 Q86Z14 Q8TBX8 Q8WU20 Q8WWG1 Q92569 Q92731 Q99075 Q99755 Q99836 Q9GZV9 Q9HCT0 Q9NP95 Q9NWZ3 Q9UQC2 Q9Y4H2 Q9Y4K3	AKT1 AREG AREGB ARHG BCAP BTC C9orf26 CD135 CD19 CD28 CD28LG CD28LG1 CD28LG2 CD80 CD86 DER4 DIF2 DTR DTS EGF EGFR EPGN ERBB ERBB1 ERBB2 EREG ERK1 ERK2 ESR ESR1 ESR2 ESTRB FGF1 FGF10 FGF16 FGF18 FGF19 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB FGFR4 FLK2 FLT3 FLT3LG FRS2 FYN GAB1 GAB2 GGF GRB1 HBEGF HEGFL HER1 HER2 HGF HGL HPTA HRGA HST HST2 HSTF1 HSTF2 HYPF IER3 IEX1 IL1F11 IL1RL1 IL33 INS INSR INT2 IRAK IRAK1 IRAK4 IRS1 IRS2 JTK2 KGF KIAA0044 KIAA0571 KIAA0589 KIT KLB KS3 LAB7 LCK MAPK1 MAPK3 MET MLN19 MYD88 NDF NEU NFHEV NGL NR3A1 NR3A2 NRG1 NRG2 NRG3 NRG4 NTAK PDGF2 PDGFB PDGFR PDGFR1 PDGFR2 PDGFRA PDGFRB PI5P4KA PIK3AP1 PIK3C1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PIP4K2A PIP4K2B PIP4K2C PIP5K1A PIP5K1B PIP5K1C PIP5K2 PIP5K2A PIP5K2B PIP5K2C PKB PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PRG1 PRKM1 PRKM2 PRKM3 PTP2C PTPN11 RAC RAC1 RAC2 RHEPDGFRA RHOG RNF85 SCFR SDGF SHPTP2 SIS SMDF SRC SRC1 ST2 STK1 STM7 STRN T1 TC25 TCRIM TGFA TKF TRAF6 TRAT1 VAV VAV1
Constitutive Signaling by Aberrant PI3K in Cancer	Amphiregulin B-lymphocyte antigen CD19 Beta-klotho Epidermal growth factor receptor Epigen Estrogen receptor beta Estrogen receptor Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 19 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fms-related tyrosine kinase 3 ligand GRB2-associated-binding protein 1 GRB2-associated-binding protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Insulin receptor substrate 1 Insulin receptor substrate 2 Mast/stem cell growth factor receptor Kit Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Phosphoinositide 3-kinase adapter protein 1 Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit B Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase Src Proto-oncogene vav Protransforming growth factor alpha Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 2 Receptor tyrosine-protein kinase erbB-2 Receptor-type tyrosine-protein kinase FLT3 Rho-related GTP-binding protein RhoG Striatin T-cell receptor-associated transmembrane adapter 1 T-cell-specific surface glycoprotein CD28 T-lymphocyte activation antigen CD80 T-lymphocyte activation antigen CD86 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lck Tyrosine-protein phosphatase non-receptor type 11	O00329 O00459 O14511 O14944 O15520 O43320 O43815 O76093 O95750 P00533 P01127 P01133 P01135 P03372 P04626 P05230 P06239 P06241 P08581 P08620 P09038 P09619 P10721 P10747 P10767 P11487 P12931 P14210 P15153 P15391 P15498 P15514 P16234 P21781 P22455 P27986 P31371 P33681 P35070 P35568 P36888 P42081 P42336 P42338 P49771 P56975 P63000 P84095 Q02297 Q06124 Q13480 Q6PIZ9 Q6UW88 Q6ZUJ8 Q86Z14 Q8WU20 Q8WWG1 Q92569 Q92731 Q99075 Q9GZV9 Q9HCT0 Q9NP95 Q9UQC2 Q9Y4H2	AREG AREGB ARHG BCAP BTC CD135 CD19 CD28 CD28LG CD28LG1 CD28LG2 CD80 CD86 DTR DTS EGF EGFR EPGN ERBB ERBB1 ERBB2 EREG ESR ESR1 ESR2 ESTRB FGF1 FGF10 FGF16 FGF18 FGF19 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB FGFR4 FLK2 FLT3 FLT3LG FRS2 FYN GAB1 GAB2 GGF GRB1 HBEGF HEGFL HER1 HER2 HGF HGL HPTA HRGA HST HST2 HSTF1 HSTF2 HYPF INT2 IRS1 IRS2 JTK2 KGF KIAA0571 KIT KLB KS3 LAB7 LCK MET MLN19 NDF NEU NGL NR3A1 NR3A2 NRG1 NRG2 NRG3 NRG4 NTAK PDGF2 PDGFB PDGFR PDGFR1 PDGFR2 PDGFRA PDGFRB PIK3AP1 PIK3C1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PTP2C PTPN11 RAC1 RAC2 RHEPDGFRA RHOG SCFR SDGF SHPTP2 SIS SMDF SRC SRC1 STK1 STRN TC25 TCRIM TGFA TKF TRAT1 VAV VAV1
Interleukin receptor SHC signaling	Cytokine receptor common subunit beta Cytokine receptor common subunit gamma GRB2-associated-binding protein 2 Granulocyte-macrophage colony-stimulating factor receptor subunit alpha Granulocyte-macrophage colony-stimulating factor Interleukin-2 receptor subunit alpha Interleukin-2 receptor subunit beta Interleukin-2 Interleukin-3 receptor subunit alpha Interleukin-3 Interleukin-5 receptor subunit alpha Interleukin-5 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform SHC-transforming protein 1 Son of sevenless homolog 1 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase JAK3 Tyrosine-protein phosphatase non-receptor type 6	O00329 O00459 O15357 O60674 P01589 P04141 P05113 P08700 P14784 P15509 P23458 P26951 P27986 P29350 P29353 P31785 P32927 P42336 P42338 P52333 P60568 Q01344 Q07889 Q92569 Q92835 Q9UQC2	CSF2 CSF2R CSF2RA CSF2RB CSF2RY GAB2 GMCSF GRB1 HCP IL15RB IL2 IL2RA IL2RB IL2RG IL3 IL3R IL3RA IL3RB IL5 IL5R IL5RA IL5RB INPP5D INPPL1 JAK1 JAK1A JAK1B JAK2 JAK3 KIAA0571 PIK3C1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PTP1C PTPN6 SHC SHC1 SHCA SHIP SHIP1 SHIP2 SOS1
Interleukin-3, Interleukin-5 and GM-CSF signaling	14-3-3 protein zeta/delta Cytokine receptor common subunit beta Granulocyte-macrophage colony-stimulating factor receptor subunit alpha Granulocyte-macrophage colony-stimulating factor Interleukin-3 receptor subunit alpha Interleukin-3 Interleukin-5 receptor subunit alpha Interleukin-5 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Proto-oncogene vav SHC-transforming protein 1 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tec Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6 cAMP-dependent protein kinase catalytic subunit alpha	O00329 O00459 O60674 P04141 P05113 P08700 P15498 P15509 P17612 P26951 P27986 P29350 P29353 P32927 P42229 P42336 P42338 P42680 P51692 P63104 Q01344 Q06124 Q92569	CSF2 CSF2R CSF2RA CSF2RB CSF2RY GMCSF GRB1 HCP IL3 IL3R IL3RA IL3RB IL5 IL5R IL5RA IL5RB JAK2 PIK3C1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PKACA PRKACA PSCTK4 PTP1C PTP2C PTPN11 PTPN6 SHC SHC1 SHCA SHPTP2 STAT5 STAT5A STAT5B TEC VAV VAV1 YWHAZ
Regulation of signaling by CBL	Adapter molecule crk B-cell linker protein Crk-like protein E3 ubiquitin-protein ligase CBL Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Proto-oncogene vav Rap guanine nucleotide exchange factor 1 Tyrosine-protein kinase Fyn Tyrosine-protein kinase HCK Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Tyrosine-protein kinase Yes	O00329 O00459 P06241 P07947 P07948 P08631 P15498 P22681 P27986 P42336 P42338 P43405 P46108 P46109 Q13905 Q8WV28 Q92569	BASH BLNK CBL CBL2 CRK CRKL FYN GRB1 GRF2 HCK JTK8 LYN PIK3C1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 RAPGEF1 RNF55 SLP65 SYK VAV VAV1 YES YES1
Signaling by CSF1 (M-CSF) in myeloid cells	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 E3 ubiquitin-protein ligase CBL GRB2-associated-binding protein 2 GRB2-associated-binding protein 3 GRB2-related adapter protein 2 GTPase KRas Interleukin-34 Macrophage colony-stimulating factor 1 receptor Macrophage colony-stimulating factor 1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Polyubiquitin-B Polyubiquitin-C Proto-oncogene tyrosine-protein kinase Src SHC-transforming protein 1 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Son of sevenless homolog 1 THO complex subunit 5 homolog Tyrosine-protein kinase Fyn Tyrosine-protein kinase HCK Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00329 O15357 O75791 P01116 P06241 P07333 P07947 P07948 P08631 P09603 P0CG47 P0CG48 P12931 P16885 P22681 P27986 P29353 P40763 P42224 P42336 P42338 P62979 P62987 Q06124 Q07889 Q13769 Q6ZMJ4 Q8WWW8 Q92835 Q9UQC2	APRF C16orf77 C22orf19 CBL CBL2 CSF1 CSF1R FMS FYN GAB2 GAB3 GADS GRAP2 GRB1 GRB2L GRID HCK IL34 INPP5D INPPL1 JTK8 KIAA0571 KIAA0983 KRAS KRAS2 LYN PIK3C1 PIK3CA PIK3CB PIK3CD PIK3R1 PLCG2 PTP2C PTPN11 RASK2 RNF55 RPS27A SHC SHC1 SHCA SHIP SHIP1 SHIP2 SHPTP2 SOS1 SRC SRC1 STAT1 STAT3 THOC5 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 YES YES1
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	Erythropoietin receptor Erythropoietin GRB2-associated-binding protein 1 Insulin receptor substrate 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Phosphoinositide 3-kinase regulatory subunit 5 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn	O00329 O60674 P01588 P07948 P19235 P27986 P42336 P42338 P48736 Q13480 Q8WYR1 Q9Y4H2	EPO EPOR GAB1 GRB1 IRS2 JAK2 JTK8 LYN PIK3C1 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R5
Regulation of pyruvate dehydrogenase (PDH) complex	Dihydrolipoyl dehydrogenase, mitochondrial Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial Maleylacetoacetate isomerase NAD-dependent protein lipoamidase sirtuin-4, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial Pyruvate dehydrogenase E1 component subunit beta, mitochondrial Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial Pyruvate dehydrogenase protein X component, mitochondrial [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial	O00330 O43708 P08559 P09622 P10515 P11177 P29803 Q15118 Q15119 Q15120 Q16654 Q8NCN5 Q9P0J1 Q9P2J9 Q9Y6E7	DLAT DLD DLTA GCSL GSTZ1 KIAA1348 KIAA1990 LAD MAAI PDHA1 PDHA2 PDHAL PDHB PDHK1 PDHK2 PDHK3 PDHK4 PDHX PDK1 PDK2 PDK3 PDK4 PDP PDP1 PDP2 PDPR PDX1 PHE1A PHE1B PHE3 PPM2C SIR2L4 SIRT4
Signaling by Retinoic Acid	Carnitine O-palmitoyltransferase 1, liver isoform Carnitine O-palmitoyltransferase 1, muscle isoform Cellular retinoic acid-binding protein 2 Dihydrolipoyl dehydrogenase, mitochondrial Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial Fatty acid-binding protein 5 Peroxisome proliferator-activated receptor delta Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial Pyruvate dehydrogenase E1 component subunit beta, mitochondrial Pyruvate dehydrogenase protein X component, mitochondrial Retinoic acid receptor RXR-alpha Retinoic acid receptor RXR-beta Retinoic acid receptor RXR-gamma Retinoic acid receptor alpha Retinoic acid receptor beta Retinoic acid receptor gamma [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial	O00330 P08559 P09622 P10276 P10515 P10826 P11177 P13631 P19793 P28702 P29373 P29803 P48443 P50416 Q01469 Q03181 Q15118 Q15119 Q15120 Q16654 Q92523	CPT1 CPT1A CPT1B CRABP2 DLAT DLD DLTA FABP5 GCSL HAP KIAA1670 LAD NR1B1 NR1B2 NR1B3 NR1C2 NR2B1 NR2B2 NR2B3 PDHA1 PDHA2 PDHAL PDHB PDHK1 PDHK2 PDHK3 PDHK4 PDHX PDK1 PDK2 PDK3 PDK4 PDX1 PHE1A PHE1B PHE3 PPARB PPARD RARA RARB RARG RXRA RXRB RXRG
PDH complex synthesizes acetyl-CoA from PYR	Dihydrolipoyl dehydrogenase, mitochondrial Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial Pyruvate dehydrogenase E1 component subunit beta, mitochondrial Pyruvate dehydrogenase protein X component, mitochondrial	O00330 P08559 P09622 P10515 P11177 P29803	DLAT DLD DLTA GCSL LAD PDHA1 PDHA2 PDHAL PDHB PDHX PDX1 PHE1A PHE1B PHE3
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	ADP-ribosylation factor-like protein 2-binding protein ADP-ribosylation factor-like protein 2 ADP/ATP translocase 1 ADP/ATP translocase 2 ADP/ATP translocase 3 Equilibrative nucleoside transporter 1 Equilibrative nucleoside transporter 2 Equilibrative nucleoside transporter 3 Equilibrative nucleoside transporter 4 Sodium/nucleoside cotransporter 1 Sodium/nucleoside cotransporter 2 Solute carrier family 28 member 3	O00337 O43868 P05141 P12235 P12236 P36404 Q14542 Q7RTT9 Q99808 Q9BZD2 Q9HAS3 Q9Y2Y0	AAC1 AAC2 AAC3 ANT1 ANT2 ANT3 ARL2 ARL2BP BART BART1 CNT1 CNT2 CNT3 DER12 ENT1 ENT2 ENT3 ENT4 HNP36 PMAT SLC25A4 SLC25A5 SLC25A6 SLC28A1 SLC28A2 SLC28A3 SLC29A1 SLC29A2 SLC29A3 SLC29A4
Cytosolic sulfonation of small molecules	3'(2'),5'-bisphosphate nucleotidase 1 Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase Podocalyxin-like protein 2 Protein-tyrosine sulfotransferase 1 Protein-tyrosine sulfotransferase 2 Putative protein-lysine deacylase ABHD14B Sulfotransferase 1A1 Sulfotransferase 1A2 Sulfotransferase 1A3 Sulfotransferase 1A4 Sulfotransferase 1B1 Sulfotransferase 1C2 Sulfotransferase 1C4 Sulfotransferase 1E1 Sulfotransferase 2A1 Sulfotransferase 4A1 Sulfotransferase 6B1	O00338 O43704 O60507 O60704 O75897 O95861 P0DMM9 P0DMN0 P49888 P50225 P50226 Q06520 Q6IMI4 Q96IU4 Q9BR01 Q9NX62 Q9NZ53	ABHD14B BPNT1 BPNT2 CIB HST IMPA3 IMPAD1 PODXL2 ST1B2 STD STE STM STP STP1 STP2 SULT1A1 SULT1A2 SULT1A3 SULT1A4 SULT1B1 SULT1B2 SULT1C1 SULT1C2 SULT1C4 SULT1E1 SULT2A1 SULT4A1 SULT6B1 SULTX3 TPST1 TPST2
Glutamate Neurotransmitter Release Cycle	Complexin-1 Excitatory amino acid transporter 1 Excitatory amino acid transporter 2 Excitatory amino acid transporter 3 Excitatory amino acid transporter 4 Excitatory amino acid transporter 5 Glutaminase kidney isoform, mitochondrial Glutaminase liver isoform, mitochondrial Liprin-alpha-1 Liprin-alpha-2 Liprin-alpha-3 Liprin-alpha-4 PRA1 family protein 3 Peripheral-type benzodiazepine receptor-associated protein 1 Protein unc-13 homolog B Ras-related protein Rab-3A Regulating synaptic membrane exocytosis protein 1 Sodium-coupled neutral amino acid symporter 2 Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Vesicle-associated membrane protein 2 Vesicular glutamate transporter 1	O00341 O14795 O14810 O75145 O75334 O75335 O75915 O94925 O95153 P20336 P21579 P43003 P43004 P43005 P48664 P60880 P63027 Q13136 Q16623 Q86UR5 Q96QD8 Q9P2U7 Q9UI32	ARL6IP5 ATA2 BNPI BZRAP1 CPLX1 DERP11 EAAC1 EAAT1 EAAT2 EAAT3 EAAT4 EAAT5 GA GLAST GLAST1 GLS GLS1 GLS2 GLT1 HEAAC1 JWA KIAA0340 KIAA0612 KIAA0654 KIAA0838 KIAA0897 KIAA1382 LIP1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 PRA2 PRAF3 RAB3A RAB3IP2 RBP1 RIM1 RIMBP1 RIMS1 SAT2 SLC17A7 SLC1A1 SLC1A2 SLC1A3 SLC1A6 SLC1A7 SLC38A2 SNAP SNAP25 SNAT2 STX1 STX1A SVP65 SYB2 SYT SYT1 TSPOAP1 UNC13 UNC13B VAMP2 VGLUT1
Transport of inorganic cations/anions and amino acids/oligopeptides	Cystinosin Excitatory amino acid transporter 1 Excitatory amino acid transporter 2 Excitatory amino acid transporter 3 Excitatory amino acid transporter 4 Excitatory amino acid transporter 5 Mitochondrial S-adenosylmethionine carrier protein Vesicular inhibitory amino acid transporter	O00341 O60931 P43003 P43004 P43005 P48664 Q70HW3 Q9H598	CTNS EAAC1 EAAT1 EAAT2 EAAT3 EAAT4 EAAT5 GLAST GLAST1 GLT1 HEAAC1 SAMC SLC1A1 SLC1A2 SLC1A3 SLC1A6 SLC1A7 SLC25A26 SLC32A1 VGAT VIAAT
P2Y receptors	Lysophosphatidic acid receptor 4 Lysophosphatidic acid receptor 6 P2Y purinoceptor 11 P2Y purinoceptor 12 P2Y purinoceptor 13 P2Y purinoceptor 14 P2Y purinoceptor 1 P2Y purinoceptor 2 P2Y purinoceptor 4 P2Y purinoceptor 6 Putative P2Y purinoceptor 10 Uracil nucleotide/cysteinyl leukotriene receptor	O00398 P41231 P43657 P47900 P51582 Q13304 Q15077 Q15391 Q96G91 Q99677 Q9BPV8 Q9H244	GPR105 GPR17 GPR23 GPR86 GPR94 HORK3 KIAA0001 LPA4 LPAR4 LPAR6 NRU P2RU1 P2RY1 P2RY10 P2RY11 P2RY12 P2RY13 P2RY14 P2RY2 P2RY4 P2RY5 P2RY6 P2RY9
COPI-mediated anterograde transport	ADP-ribosylation factor 1 ADP-ribosylation factor 3 ADP-ribosylation factor 4 ADP-ribosylation factor 5 ADP-ribosylation factor GTPase-activating protein 1 ADP-ribosylation factor GTPase-activating protein 2 ADP-ribosylation factor GTPase-activating protein 3 Actin-related protein 10 Alpha-centractin Alpha-soluble NSF attachment protein Ankyrin-1 Ankyrin-2 Ankyrin-3 BET1 homolog BET1-like protein Beta-soluble NSF attachment protein CD59 glycoprotein Coatomer subunit alpha Coatomer subunit beta' Coatomer subunit beta Coatomer subunit delta Coatomer subunit epsilon Coatomer subunit gamma-1 Coatomer subunit gamma-2 Coatomer subunit zeta-1 Coatomer subunit zeta-2 Complement decay-accelerating factor Conserved oligomeric Golgi complex subunit 1 Conserved oligomeric Golgi complex subunit 2 Conserved oligomeric Golgi complex subunit 3 Conserved oligomeric Golgi complex subunit 4 Conserved oligomeric Golgi complex subunit 5 Conserved oligomeric Golgi complex subunit 6 Conserved oligomeric Golgi complex subunit 7 Conserved oligomeric Golgi complex subunit 8 Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 Dynactin subunit 1 Dynactin subunit 2 Dynactin subunit 3 Dynactin subunit 4 Dynactin subunit 5 Dynactin subunit 6 Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic ER lumen protein-retaining receptor 1 ER lumen protein-retaining receptor 2 ER lumen protein-retaining receptor 3 F-actin-capping protein subunit alpha-1 F-actin-capping protein subunit alpha-2 F-actin-capping protein subunit alpha-3 F-actin-capping protein subunit beta Folate receptor alpha Gamma-soluble NSF attachment protein General vesicular transport factor p115 Golgi SNAP receptor complex member 1 Golgi SNAP receptor complex member 2 Golgi reassembly-stacking protein 1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 Golgin subfamily A member 2 Golgin subfamily B member 1 Insulin Ras-related protein Rab-1A Ras-related protein Rab-1B Spectrin alpha chain, erythrocytic 1 Spectrin alpha chain, non-erythrocytic 1 Spectrin beta chain, erythrocytic Spectrin beta chain, non-erythrocytic 1 Spectrin beta chain, non-erythrocytic 2 Spectrin beta chain, non-erythrocytic 4 Spectrin beta chain, non-erythrocytic 5 Synaptobrevin homolog YKT6 Syntaxin-5 Transmembrane emp24 domain-containing protein 10 Transmembrane emp24 domain-containing protein 2 Transmembrane emp24 domain-containing protein 3 Transmembrane emp24 domain-containing protein 7 Transmembrane emp24 domain-containing protein 9 Transmembrane protein 115 Vesicle-fusing ATPase	O00399 O14576 O14579 O14653 O15020 O15155 O15498 O43237 O43731 O60763 O75935 O95249 P01308 P02549 P08174 P11277 P13987 P15328 P16157 P18085 P24390 P33947 P35606 P46459 P47755 P47756 P48444 P49755 P52907 P53618 P53621 P54920 P61163 P61204 P61923 P62820 P63167 P83436 P84077 P84085 Q01082 Q01484 Q08379 Q12893 Q12955 Q13190 Q13409 Q13561 Q13813 Q14203 Q14204 Q14746 Q14789 Q15363 Q8N6H7 Q8N6T3 Q8WTW3 Q92538 Q96FJ2 Q96JB2 Q96KX2 Q96MW5 Q99747 Q9BQQ3 Q9BTE1 Q9BVK6 Q9H0U4 Q9H115 Q9H254 Q9H9E3 Q9NP61 Q9NRC6 Q9NYM9 Q9NZ32 Q9P299 Q9UBF2 Q9UJW0 Q9UP83 Q9Y2V7 Q9Y3B3 Q9Y3Q3 Q9Y678 Q9Y6G9	ACTR10 ACTR11 ACTR1A ANK ANK1 ANK2 ANK3 ANKB ARCN1 ARF1 ARF1GAP ARF2 ARF3 ARF4 ARF5 ARFGAP1 ARFGAP2 ARFGAP3 ARP10 ARP11 BET1 BET1L BSPECV C15orf22 CAPAA3 CAPZA1 CAPZA2 CAPZA3 CAPZB CD55 CD59 COG1 COG2 COG3 COG4 COG5 COG6 COG7 COG8 COPA COPB COPB1 COPB2 COPD COPE COPG COPG1 COPG2 COPZ COPZ1 COPZ2 CR CTRN1 DAF DCTN1 DCTN2 DCTN22 DCTN3 DCTN4 DCTN5 DCTN50 DCTN6 DHC1 DLC1 DLC2 DNCH1 DNCI1 DNCI2 DNCIC1 DNCIC2 DNCL DNCL1 DNCLC1 DNCLI1 DNCLI2 DNECL DYHC DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 ERD2.1 ERD2.2 ERD23 FOLR FOLR1 GBF1 GOLGA2 GOLGB1 GOLPH5 GOLTC1 GORASP1 GOSR1 GOSR2 GP25L2 GRASP65 GS15 GS27 GS28 GSG3 GTC90 HDLC1 HUBSPECV HUSPECV INS KDELR1 KDELR2 KDELR3 KIAA0248 KIAA0302 KIAA0325 KIAA1134 KIAA1381 KIAA1642 LDLB LDLC LIC2 MIC11 MIN1 MIN2 MIN3 MSK21 NAPA NAPB NAPG NEAS NSF PL6 RAB1 RAB1A RAB1B RNP24 SCA5 SEC34 SNAPA SNAPB SNAPG SPTA SPTA1 SPTA2 SPTAN1 SPTB SPTB1 SPTB2 SPTBN1 SPTBN2 SPTBN3 SPTBN4 SPTBN5 STX5 STX5A TMED10 TMED2 TMED3 TMED7 TMED9 TMEM115 TMP21 USO1 VDP WS3 YKT6 ZNF289
COPI-independent Golgi-to-ER retrograde traffic	1-acyl-sn-glycerol-3-phosphate acyltransferase gamma 85/88 kDa calcium-independent phospholipase A2 Actin-related protein 10 Alpha-centractin Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 Cytosolic phospholipase A2 Dynactin subunit 1 Dynactin subunit 2 Dynactin subunit 3 Dynactin subunit 4 Dynactin subunit 5 Dynactin subunit 6 Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic F-actin-capping protein subunit alpha-1 F-actin-capping protein subunit alpha-2 F-actin-capping protein subunit alpha-3 F-actin-capping protein subunit beta Platelet-activating factor acetylhydrolase IB subunit alpha1 Platelet-activating factor acetylhydrolase IB subunit alpha2 Platelet-activating factor acetylhydrolase IB subunit beta Polypeptide N-acetylgalactosaminyltransferase 1 Polypeptide N-acetylgalactosaminyltransferase 2 Protein bicaudal D homolog 1 Protein bicaudal D homolog 2 Rab3 GTPase-activating protein catalytic subunit Rab3 GTPase-activating protein non-catalytic subunit Ras-related protein Rab-18 Ras-related protein Rab-6A Ras-related protein Rab-6B	O00399 O14576 O43237 O60733 O75935 P20340 P43034 P47712 P47755 P47756 P52907 P61163 P63167 P68402 Q10471 Q10472 Q13409 Q13561 Q14203 Q14204 Q15042 Q15102 Q8TD16 Q96FJ2 Q96G01 Q96KX2 Q9BTE1 Q9H2M9 Q9NP72 Q9NRW1 Q9NRZ7 Q9NZ32 Q9UJW0 Q9Y6G9	ACTR10 ACTR11 ACTR1A AGPAT3 ARP10 ARP11 BICD1 BICD2 CAPAA3 CAPZA1 CAPZA2 CAPZA3 CAPZB CPLA2 CTRN1 DCTN1 DCTN2 DCTN22 DCTN3 DCTN4 DCTN5 DCTN50 DCTN6 DHC1 DLC1 DLC2 DNCH1 DNCI1 DNCI2 DNCIC1 DNCIC2 DNCL DNCL1 DNCLC1 DNCLI1 DNCLI2 DNECL DYHC DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 GALNT1 GALNT2 GSG3 HDLC1 KIAA0066 KIAA0325 KIAA0699 KIAA0839 LIC2 LIS1 LPAAT3 MDCR MDS PAFAH1B1 PAFAH1B2 PAFAH1B3 PAFAHA PAFAHB PAFAHG PLA2G4 PLA2G4A PLA2G6 PLPLA9 RAB18 RAB3GAP RAB3GAP1 RAB3GAP2 RAB6 RAB6A RAB6B WS3
HSP90 chaperone cycle for SHRs	Actin-related protein 10 Alpha-centractin Androgen receptor Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 DnaJ homolog subfamily A member 1 DnaJ homolog subfamily A member 2 DnaJ homolog subfamily A member 4 DnaJ homolog subfamily B member 1 Dynactin subunit 1 Dynactin subunit 2 Dynactin subunit 3 Dynactin subunit 4 Dynactin subunit 5 Dynactin subunit 6 Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic F-actin-capping protein subunit alpha-1 F-actin-capping protein subunit alpha-2 F-actin-capping protein subunit alpha-3 F-actin-capping protein subunit beta Glucocorticoid receptor Heat shock 70 kDa protein 1-like Heat shock 70 kDa protein 1A Heat shock 70 kDa protein 1B Heat shock cognate 71 kDa protein Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heat shock-related 70 kDa protein 2 Mineralocorticoid receptor Peptidyl-prolyl cis-trans isomerase FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP5 Progesterone receptor Prostaglandin E synthase 3 Stress-induced-phosphoprotein 1	O00399 O14576 O43237 O60884 O75935 P04150 P06401 P07900 P08235 P08238 P0DMV8 P0DMV9 P10275 P11142 P25685 P31689 P31948 P34931 P47755 P47756 P52907 P54652 P61163 P63167 Q02790 Q13409 Q13451 Q13561 Q14203 Q14204 Q15185 Q8WW22 Q96FJ2 Q96KX2 Q9BTE1 Q9NZ32 Q9UJW0 Q9Y6G9	ACTR10 ACTR11 ACTR1A AIG6 AR ARP10 ARP11 CAPAA3 CAPZA1 CAPZA2 CAPZA3 CAPZB CPR3 CTRN1 DCTN1 DCTN2 DCTN22 DCTN3 DCTN4 DCTN5 DCTN50 DCTN6 DHC1 DHTR DLC1 DLC2 DNAJ1 DNAJ2 DNAJA1 DNAJA2 DNAJA4 DNAJB1 DNCH1 DNCI1 DNCI2 DNCIC1 DNCIC2 DNCL DNCL1 DNCLC1 DNCLI1 DNCLI2 DNECL DYHC DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 FKBP4 FKBP5 FKBP51 FKBP52 GRL GSG3 HDJ1 HDJ2 HDLC1 HIRIP4 HSC70 HSJ2 HSP72 HSP73 HSP90A HSP90AA1 HSP90AB1 HSP90B HSPA1 HSPA10 HSPA1A HSPA1B HSPA1L HSPA2 HSPA8 HSPC1 HSPC2 HSPC3 HSPCA HSPCB HSPF1 HSPF4 HSX70 KIAA0325 LIC2 MCR MLR NR3C1 NR3C2 NR3C3 NR3C4 P23 PGR PTGES3 STIP1 TEBP WS3
Transport of vitamins, nucleosides, and related molecules	Acetyl-coenzyme A transporter 1 PDZ domain-containing protein 11 Sodium-dependent multivitamin transporter	O00400 Q5EBL8 Q9Y289	ACATN AIPP1 AT1 PDZD11 PDZK11 PISP SLC33A1 SLC5A6 SMVT
Defective SLC33A1 causes spastic paraplegia 42 (SPG42)	Acetyl-coenzyme A transporter 1	O00400	ACATN AT1 SLC33A1
Nephrin family interactions	Actin nucleation-promoting factor WASL Alpha-actinin-1 Alpha-actinin-2 Alpha-actinin-3 Alpha-actinin-4 CD2-associated protein Cytoplasmic protein NCK2 Kin of IRRE-like protein 1 Kin of IRRE-like protein 2 Kin of IRRE-like protein 3 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 Nephrin Peripheral plasma membrane protein CASK Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Ras GTPase-activating-like protein IQGAP1 SH2/SH3 adapter protein NCK1 Spectrin alpha chain, non-erythrocytic 1 Spectrin beta chain, non-erythrocytic 1 Tyrosine-protein kinase Fyn	O00401 O00459 O14936 O43639 O43707 O60500 P06241 P12814 P16333 P27986 P35609 P42336 P42338 P46940 Q01082 Q08043 Q13813 Q6UWL6 Q86UL8 Q8IZU9 Q96J84 Q9Y5K6	ACTN1 ACTN2 ACTN3 ACTN4 ACVRINP1 AIP1 CASK CD2AP FYN GRB1 GRB4 IQGAP1 KIAA0051 KIAA0705 KIAA1867 KIRREL KIRREL1 KIRREL2 KIRREL3 LIN2 MAGI2 NCK NCK1 NCK2 NEAS NEPH1 NEPH2 NEPH3 NPHN NPHS1 PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 SPTA2 SPTAN1 SPTB2 SPTBN1 WASL
DCC mediated attractive signaling	Actin nucleation-promoting factor WASL Actin-binding LIM protein 1 Actin-binding LIM protein 2 Actin-binding LIM protein 3 Cell division control protein 42 homolog Dedicator of cytokinesis protein 1 Focal adhesion kinase 1 Netrin receptor DCC Netrin-1 Proto-oncogene tyrosine-protein kinase Src Ras-related C3 botulinum toxin substrate 1 SH2/SH3 adapter protein NCK1 Triple functional domain protein	O00401 O14639 O75962 O94929 O95631 P12931 P16333 P43146 P60953 P63000 Q05397 Q14185 Q6H8Q1	ABLIM ABLIM1 ABLIM2 ABLIM3 CDC42 DCC DOCK1 FAK FAK1 IGDCC1 KIAA0059 KIAA0843 KIAA1808 LIMAB1 NCK NCK1 NTN1 NTN1L PTK2 RAC1 SRC SRC1 TC25 TRIO WASL
EPHB-mediated forward signaling	Actin nucleation-promoting factor WASL Actin, cytoplasmic 1 Actin, cytoplasmic 2 Actin-related protein 2/3 complex subunit 1A Actin-related protein 2/3 complex subunit 1B Actin-related protein 2/3 complex subunit 2 Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2 Actin-related protein 3 Cell division control protein 42 homolog Cofilin-1 Focal adhesion kinase 1 GTPase HRas Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2B Intersectin-1 Kalirin LIM domain kinase 1 LIM domain kinase 2 Ras GTPase-activating protein 1 Ras-related C3 botulinum toxin substrate 1 Rho guanine nucleotide exchange factor 28 Rho guanine nucleotide exchange factor TIAM1 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Serine/threonine-protein kinase PAK 1 Syndecan-2 Transforming protein RhoA Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes	O00401 O15143 O15144 O15145 O15511 O60229 O75116 P01112 P06241 P07947 P07948 P20936 P23528 P34741 P53667 P53671 P59998 P60709 P60953 P61158 P61160 P61586 P63000 P63261 Q05397 Q05586 Q13009 Q13153 Q13224 Q13464 Q15811 Q8N1W1 Q92747	ACTB ACTG ACTG1 ACTR2 ACTR3 ARC16 ARC20 ARC21 ARC34 ARC41 ARH12 ARHA ARHGEF28 ARP2 ARP3 ARPC1A ARPC1B ARPC2 ARPC3 ARPC4 ARPC5 CDC42 CFL CFL1 DUET DUO FAK FAK1 FYN GAP GRIN1 GRIN2B HAPIP HRAS HRAS1 HSPG1 ITSN ITSN1 JTK8 KALRN KIAA0619 KIAA1998 LIMK LIMK1 LIMK2 LYN NMDAR1 NMDAR2B PAK1 PTK2 RAC1 RASA RASA1 RGNEF RHO12 RHOA ROCK1 ROCK2 SDC2 SH3D1A SOP2L TC25 TIAM1 TRAD WASL YES YES1

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