GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **701 - 725** of **2090** in total

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Pathway Name ▼	Protein Name	UniProt ID	Gene Symbol
RHOH GTPase cycle	Caveolin-1 Drebrin Junction plakoglobin Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial Methionine synthase NSFL1 cofactor p47 Neutral amino acid transporter B(0) Oxysterol-binding protein-related protein 11 Protein FAM91A1 Protein NipSnap homolog 2 Ragulator complex protein LAMTOR1 Ral GTPase-activating protein subunit alpha-1 Ras-related protein Rab-7a Rho GDP-dissociation inhibitor 1 Rho GDP-dissociation inhibitor 2 Rho GDP-dissociation inhibitor 3 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Rho-related GTP-binding protein RhoH Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 4 Serine/threonine-protein kinase PAK 5 Serine/threonine-protein kinase PAK 6 Sodium bicarbonate cotransporter 3 Stomatin Transferrin receptor protein 1 Transitional endoplasmic reticulum ATPase Transmembrane protein 59 Tubulin alpha-1B chain Tyrosine-protein kinase CSK Tyrosine-protein kinase Lck Tyrosine-protein kinase ZAP-70 Uveal autoantigen with coiled-coil domains and ankyrin repeats Vang-like protein 1 Vesicle-associated membrane protein 3 WD repeat-containing protein 11	O75116 O75323 O96013 P02786 P06239 P11182 P14923 P27105 P41240 P43403 P51149 P52565 P52566 P55072 P68363 Q03135 Q13153 Q13177 Q13464 Q15669 Q15758 Q15836 Q16643 Q658Y4 Q6GYQ0 Q6IAA8 Q8TAA9 Q99707 Q99819 Q9BXB4 Q9BXS4 Q9BZF9 Q9BZH6 Q9NQU5 Q9P286 Q9UNZ2 Q9Y6M7	ARHGDIA ARHGDIB ARHGDIG ARHH ASCT2 BCATE2 BCKDHE2 BND7 BRWD2 BT C11orf59 C1orf8 CAV CAV1 CSK CTNNG D0S117E DBN1 DBT DP3 EPB72 FAM91A1 GARNL1 GBAS GDIA1 GDIA2 GDID4 HEL-220 HEL-S-70 JUP KIAA0619 KIAA0884 KIAA1142 KIAA1264 KIAA1351 KIAA1561 LAMTOR1 LCK M7V1 MTR NBC2 NBC2B NBC3 NBCn1 NIPSNAP2 NSFL1C ORP11 OSBP12 OSBPL11 PAK1 PAK2 PAK4 PAK5 PAK6 PAK7 PDRO RAB7 RAB7A RALGAPA1 RAP1GN1 RDR RDRC RHOH ROCK1 ROCK2 SBC2 SLC1A5 SLC4A6 SLC4A7 SRK STB2 STOM SYB3 TFRC TMEM59 TTF TUBA1B TULIP1 UACA UBXN2C VAMP3 VANGL1 VCP WDR11 WDR15 ZAP70
RHOG GTPase cycle	10 kDa heat shock protein, mitochondrial ADP-ribosylation factor GTPase-activating protein 3 Ankyrin repeat and LEM domain-containing protein 2 Caveolin-1 Cdc42 effector protein 1 Cell division control protein 42 homolog Cell surface glycoprotein MUC18 Cytoplasmic FMR1-interacting protein 1 DEP domain-containing protein 1B Dedicator of cytokinesis protein 1 Dedicator of cytokinesis protein 2 Dedicator of cytokinesis protein 3 Dedicator of cytokinesis protein 4 Dedicator of cytokinesis protein 5 Delta(14)-sterol reductase LBR Desmoglein-2 Emerin Engulfment and cell motility protein 2 Ephrin type-A receptor 2 Erbin Extended synaptotagmin-1 Granule associated Rac and RHOG effector protein 1 Guanine nucleotide exchange factor DBS Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Inner nuclear membrane protein Man1 Integrin beta-1 Intersectin-1 Kalirin Kinectin Lamina-associated polypeptide 2, isoforms beta/gamma MAGUK p55 subfamily member 7 Membrane-associated progesterone receptor component 2 Mitochondrial proton/calcium exchanger protein Mitogen-activated protein kinase kinase kinase 11 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial Oligophrenin-1 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Phosphatidylinositol 3-kinase regulatory subunit alpha Phospholipase D1 Pleckstrin homology domain-containing family G member 3 Protein ERGIC-53 Protein diaphanous homolog 3 Proto-oncogene DBL Proto-oncogene vav Ragulator complex protein LAMTOR1 Ras GTPase-activating-like protein IQGAP2 Ras-related protein Rab-7a Rho GDP-dissociation inhibitor 1 Rho GDP-dissociation inhibitor 2 Rho GDP-dissociation inhibitor 3 Rho GTPase-activating protein 1 Rho GTPase-activating protein 21 Rho GTPase-activating protein 32 Rho GTPase-activating protein 35 Rho GTPase-activating protein 39 Rho GTPase-activating protein 5 Rho guanine nucleotide exchange factor 16 Rho guanine nucleotide exchange factor 26 Rho guanine nucleotide exchange factor 5 Rho-related GTP-binding protein RhoG Serine hydroxymethyltransferase, mitochondrial Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 4 Serine/threonine-protein kinase VRK2 Starch-binding domain-containing protein 1 Synaptobrevin homolog YKT6 Syntaxin-5 Transferrin receptor protein 1 Triple functional domain protein Vang-like protein 1 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein-associated protein B/C	A1L390 A7KAX9 O15063 O15068 O15173 O15498 O60229 O60890 O75489 O75962 O95202 O95210 O95292 O96013 P02786 P05556 P10911 P15498 P27986 P29317 P34897 P42167 P43121 P49257 P50402 P51149 P52565 P52566 P52735 P60953 P61604 P84095 Q00587 Q03135 Q07960 Q12774 Q13017 Q13177 Q13190 Q13393 Q13576 Q14126 Q14185 Q14739 Q15811 Q15836 Q16584 Q16718 Q5T2T1 Q5T5U3 Q5VV41 Q6IAA8 Q7L576 Q86UP2 Q86XL3 Q86Y07 Q8IZD9 Q8N1I0 Q8TAA9 Q8TCU6 Q8WUY9 Q92608 Q96DR7 Q96JJ3 Q96RT1 Q99819 Q9BSJ8 Q9C0H5 Q9H7D0 Q9NP61 Q9NRY4 Q9NSV4 Q9UKW4 Q9Y2U8	ANKLE2 ARFGAP1 ARFGAP3 ARHG ARHGAP1 ARHGAP10 ARHGAP21 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP5 ARHGDIA ARHGDIB ARHGDIG ARHGEF16 ARHGEF26 ARHGEF5 BORG5 C11orf59 CAV CAV1 CDC42 CDC42EP1 CDC42GAP CDHF5 CED12A CEP1 CG1 CYFIP1 DBL DEPDC1B DG6 DIAP3 DIAPH3 DOCK1 DOCK2 DOCK3 DOCK4 DOCK5 DSG2 DUET DUO ECK EDMD ELMO2 EMD EPHA2 EPHEXIN4 ERBB2IP ERBIN ERGIC53 ESYT1 F5F8D FAM62A FNRB GARRE1 GDIA1 GDIA2 GDID4 GRB1 GRF1 GRIT GRLF1 HAPIP HSPE1 IQGAP2 ITGB1 ITSN ITSN1 KALRN KIAA0004 KIAA0068 KIAA0209 KIAA0299 KIAA0355 KIAA0362 KIAA0599 KIAA0692 KIAA0712 KIAA0716 KIAA0747 KIAA1142 KIAA1225 KIAA1415 KIAA1424 KIAA1688 KIAA1722 KIAA1834 KTN1 LAMTOR1 LAP2 LBR LEM4 LEMD3 LETM1 LMAN1 MAN1 MAP3K11 MBC2 MCAM MCF2 MCF2L MDF2 MLK3 MOCA MPP7 MSE55 MSK12 MUC18 NBR NDUFA5 NDUFS3 OPHN1 OST P190A PAK2 PAK4 PDRO PGRMC2 PIK3R1 PLD1 PLEKHG3 PMBP PREX1 PTK1 RAB7 RAB7A RAP1GN1 RHOG RHOGAP1 RHOGAP5 RICS SGEF SH3D1A SHMT2 SPRK STA STB2 STBD1 STX5 STX5A SYB3 TFRC TIM TMPO TRAD TRIO VAMP3 VANGL1 VAPB VAV VAV1 VAV2 VAV3 VRK2 XTP8 YKT6 p190ARHOGAP
RHOF GTPase cycle	A-kinase anchor protein 12 Actin, cytoplasmic 1 Alpha-actinin-1 Ankyrin repeat domain-containing protein SOWAHC BAR/IMD domain-containing adapter protein 2-like 1 BAR/IMD domain-containing adapter protein 2-like 2 Brain acid soluble protein 1 Caveolin-1 Cell surface glycoprotein MUC18 DEP domain-containing protein 1B Extended synaptotagmin-1 F-actin-capping protein subunit beta FERM, ARHGEF and pleckstrin domain-containing protein 1 Gamma-adducin Lamin-B1 Lamina-associated polypeptide 2, isoforms beta/gamma Metalloreductase STEAP3 Myotubularin-related protein 1 POTE ankyrin domain family member E Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Protein diaphanous homolog 1 Protein diaphanous homolog 2 Protein diaphanous homolog 3 Ras-related protein Rab-7a Rho GTPase-activating protein 12 Rho GTPase-activating protein 1 Rho GTPase-activating protein 21 Rho GTPase-activating protein 32 Rho GTPase-activating protein 39 Rho GTPase-activating protein 5 Rho GTPase-activating protein SYDE1 Rho-related GTP-binding protein RhoF SLIT-ROBO Rho GTPase-activating protein 2 Sentrin-specific protease 1 Sodium bicarbonate cotransporter 3 Soluble lamin-associated protein of 75 kDa Synaptosomal-associated protein 23 Torsin-1A-interacting protein 1 Unconventional myosin-IXb Vang-like protein 1 Vesicle-associated membrane protein 3	A7KAX9 O00161 O00459 O60610 O60879 O75044 P12814 P20700 P27986 P42167 P43121 P47756 P51149 P60709 P80723 Q02952 Q03135 Q07960 Q13017 Q13459 Q13613 Q15836 Q53LP3 Q5JTV8 Q5T5U3 Q658P3 Q6S8J3 Q6UXY1 Q6ZW31 Q8IWW6 Q8TAA9 Q8WUY9 Q9BSJ8 Q9C0H5 Q9HBH0 Q9NSV4 Q9P0U3 Q9UEY8 Q9UHR4 Q9Y4F1 Q9Y6M7 Q9Y6X4	A26C1A ACTB ACTN1 ADD3 ADDL AKAP12 AKAP250 ANKRD57 ARHF ARHGAP1 ARHGAP10 ARHGAP12 ARHGAP21 ARHGAP32 ARHGAP34 ARHGAP39 ARHGAP5 BAIAP2L1 BAIAP2L2 BASP1 BT C2orf26 CAPZB CAV CAV1 CDC42GAP CDEP DEPDC1B DIA DIAP1 DIAP3 DIAPH1 DIAPH2 DIAPH3 ESYT1 FAM169A FAM62A FARP1 FNBP2 GRB1 GRIT IRTKS KIAA0456 KIAA0712 KIAA0747 KIAA0888 KIAA1424 KIAA1688 LAP1 LAP2 LMN2 LMNB LMNB1 MBC2 MCAM MTMR1 MUC18 MYO9B MYR5 NAP22 NBC2 NBC2B NBC3 NBCn1 PIK3R1 PIK3R2 PLEKHC2 POTE2 POTEE RAB7 RAB7A RHOF RHOGAP1 RHOGAP5 RICS RIF SBC2 SENP1 SLC4A6 SLC4A7 SNAP23 SOWAHC SRGAP2 SRGAP2A STB2 STEAP3 SYB3 SYDE1 TMPO TOR1AIP1 TSAP6 VAMP3 VANGL1 XTP8
RHOD GTPase cycle	A-kinase anchor protein 12 Adenosine 5'-monophosphoramidase HINT2 Alpha-actinin-1 Caveolin-1 Cell surface glycoprotein MUC18 Copine-8 DEP domain-containing protein 1B Delta(14)-sterol reductase LBR Drebrin EF-hand domain-containing protein D2 Emerin Extended synaptotagmin-1 F-actin-capping protein subunit beta Filamin-A-interacting protein 1 Gamma-adducin Golgin subfamily A member 8R Inner nuclear membrane protein Man1 Lamin-B1 Lamina-associated polypeptide 2, isoforms beta/gamma Membrane-associated progesterone receptor component 2 Metalloreductase STEAP3 Motile sperm domain-containing protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Plexin-A1 Plexin-B1 Protein ERGIC-53 Protein diaphanous homolog 1 Protein diaphanous homolog 3 Rabankyrin-5 Rac GTPase-activating protein 1 Ras-related protein Rab-7a Rho GTPase-activating protein 12 Rho GTPase-activating protein 17 Rho GTPase-activating protein 1 Rho GTPase-activating protein 21 Rho GTPase-activating protein 26 Rho GTPase-activating protein 32 Rho GTPase-activating protein 35 Rho GTPase-activating protein 39 Rho GTPase-activating protein 5 Rho-related GTP-binding protein RhoD Serine/threonine-protein kinase PAK 5 Serine/threonine-protein kinase PAK 6 Serine/threonine-protein kinase VRK2 Sodium bicarbonate cotransporter 3 Starch-binding domain-containing protein 1 Torsin-1A-interacting protein 1 Vang-like protein 1 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein-associated protein B/C WASP homolog-associated protein with actin, membranes and microtubules	A7KAX9 I6L899 O00212 O00459 O15173 O43157 O60610 O95210 O95292 P12814 P20700 P27986 P42167 P43121 P47756 P49257 P50402 P51149 Q02952 Q03135 Q07960 Q13017 Q14739 Q15836 Q16643 Q5JTV8 Q5T5U3 Q658P3 Q68EM7 Q7Z7B0 Q86Y07 Q86YQ8 Q8IWW6 Q8NHP6 Q8TAA9 Q8TF30 Q8WUY9 Q96C19 Q9BSJ8 Q9BX68 Q9C0H5 Q9H0H5 Q9NQU5 Q9NRY4 Q9NSV4 Q9P286 Q9P2R3 Q9UEY8 Q9UIW2 Q9UNA1 Q9Y2U8 Q9Y6M7	ACTN1 ADD3 ADDL AKAP12 AKAP250 ANKFY1 ANKHZN ARHD ARHGAP1 ARHGAP10 ARHGAP12 ARHGAP17 ARHGAP21 ARHGAP26 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP5 BT CAPZB CAV CAV1 CDC42GAP CPNE8 D0S117E DBN1 DEPDC1B DG6 DIAP1 DIAP3 DIAPH1 DIAPH3 EDMD EFHD2 EMD ERGIC53 ESYT1 F5F8D FAM62A FILIP1 GOLGA8R GRAF GRB1 GRF1 GRIT GRLF1 HINT2 KIAA0407 KIAA0621 KIAA0712 KIAA0747 KIAA1255 KIAA1264 KIAA1275 KIAA1424 KIAA1478 KIAA1688 KIAA1722 KIAA1971 LAP1 LAP2 LBR LEMD3 LMAN1 LMN2 LMNB LMNB1 MAN1 MBC2 MCAM MGCRACGAP MOSPD2 MUC18 NBC2 NBC2B NBC3 NBCn1 NOV OPHN1L P190A PAK5 PAK6 PAK7 PGRMC2 PIK3R1 PIK3R2 PLXN1 PLXN5 PLXNA1 PLXNB1 PMBP RAB7 RAB7A RACGAP1 RHOD RHOGAP1 RHOGAP5 RICH1 RICS SBC2 SEP SLC4A6 SLC4A7 STA STB2 STBD1 STEAP3 SWS1 SYB3 TMPO TOR1AIP1 TSAP6 VAMP3 VANGL1 VAPB VRK2 WHAMM WHDC1 XTP8 p190ARHOGAP
RHOC GTPase cycle	A-kinase anchor protein 13 ATP-binding cassette sub-family D member 3 Active breakpoint cluster region-related protein Acyl-CoA-binding domain-containing protein 5 Anillin Breakpoint cluster region protein Caveolae-associated protein 1 Caveolin-1 Cell surface glycoprotein MUC18 Citron Rho-interacting kinase Coiled-coil domain-containing protein 187 Complement component 1 Q subcomponent-binding protein, mitochondrial DEP domain-containing protein 1B Delta(14)-sterol reductase LBR Disheveled-associated activator of morphogenesis 1 Erbin Flotillin-1 Flotillin-2 Formin-like protein 2 Formin-like protein 3 Guanine nucleotide exchange factor DBS Guanine nucleotide exchange factor VAV2 Junction plakoglobin Lamina-associated polypeptide 2, isoforms beta/gamma Macoilin Oligophrenin-1 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Phosphatidylinositol 3-kinase regulatory subunit alpha Protein ERGIC-53 Protein diaphanous homolog 1 Protein diaphanous homolog 3 Proto-oncogene DBL Rac GTPase-activating protein 1 Ras GTPase-activating-like protein IQGAP1 Ras GTPase-activating-like protein IQGAP3 Rho GDP-dissociation inhibitor 1 Rho GTPase-activating protein 18 Rho GTPase-activating protein 1 Rho GTPase-activating protein 21 Rho GTPase-activating protein 26 Rho GTPase-activating protein 32 Rho GTPase-activating protein 35 Rho GTPase-activating protein 39 Rho GTPase-activating protein 5 Rho GTPase-activating protein 7 Rho guanine nucleotide exchange factor 10-like protein Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 28 Rho guanine nucleotide exchange factor 40 Rho guanine nucleotide exchange factor 5 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Rho-related GTP-binding protein RhoC Rhotekin STE20-like serine/threonine-protein kinase Serine/threonine-protein kinase 10 Serine/threonine-protein kinase N1 Serine/threonine-protein kinase N2 Serine/threonine-protein kinase N3 StAR-related lipid transfer protein 13 Stomatin Syntaxin-5 Tight junction protein ZO-2 Transferrin receptor protein 1 Transforming protein RhoA Unconventional myosin-IXb Vang-like protein 1 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein-associated protein B/C	A0A096LP49 A7KAX9 O14578 O15013 O15068 O15085 O60610 O60890 O75116 O75955 O94804 O95292 P02786 P08134 P10911 P11274 P14923 P27105 P27986 P28288 P42167 P43121 P46940 P49257 P52565 P52735 P61586 Q03135 Q07021 Q07960 Q12774 Q12802 Q12979 Q13017 Q13190 Q13459 Q13464 Q14254 Q14739 Q15836 Q16512 Q16513 Q5T5U3 Q5T8D3 Q6NZI2 Q6P5Z2 Q86VI3 Q86VW2 Q8IVF7 Q8N1W1 Q8N392 Q8N5G2 Q8TAA9 Q8TCU6 Q8TER5 Q8WUY9 Q92888 Q96PE2 Q96PY5 Q96QB1 Q96RT1 Q9BST9 Q9C0H5 Q9H0H5 Q9H2G2 Q9HCE6 Q9NQW6 Q9NRY4 Q9NSV4 Q9NZN5 Q9UDY2 Q9UNA1 Q9Y3M8 Q9Y4D1	ABCD3 ABR ACBD5 AKAP13 ANLN ARH12 ARH9 ARHA ARHC ARHGAP1 ARHGAP10 ARHGAP18 ARHGAP21 ARHGAP26 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP5 ARHGAP7 ARHGDIA ARHGEF1 ARHGEF10 ARHGEF10L ARHGEF11 ARHGEF12 ARHGEF17 ARHGEF25 ARHGEF28 ARHGEF40 ARHGEF5 BCR BCR1 BND7 BRX C1QBP CAV CAV1 CAVIN1 CCDC187 CDC42GAP CIT CRIK CTNNG D22S11 DAAM1 DBL DEPDC1B DIAP1 DIAP3 DIAPH1 DIAPH3 DLC1 DLC2 DP3 EPB72 ERBB2IP ERBIN ERGIC53 ESA1 F5F8D FHOD2 FHOD3 FLOT1 FLOT2 FMNL2 FMNL3 FRL2 GC1QBP GDIA1 GEFT GRAF GRB1 GRF1 GRINCHGEF GRIT GRLF1 GT650 HABP1 HT31 IQGAP1 IQGAP3 JUP KIAA0051 KIAA0204 KIAA0294 KIAA0337 KIAA0362 KIAA0380 KIAA0382 KIAA0619 KIAA0621 KIAA0666 KIAA0712 KIAA0949 KIAA1225 KIAA1415 KIAA1424 KIAA1478 KIAA1626 KIAA1688 KIAA1722 KIAA1723 KIAA1902 KIAA1996 KIAA1998 KIAA2014 LAP2 LARG LBC LBR LMAN1 LOK M17S1 MACO1 MCAM MCF2 MCF2L MGCRACGAP MUC18 MYO9B MYR5 OPHN1 OPHN1L OST P190A PAK1 PIK3R1 PKN PKN1 PKN2 PKN3 PKNBETA PMP70 PREX1 PRK1 PRK2 PRKCL1 PRKCL2 PTRF PXMP1 RACGAP1 RGNEF RHO12 RHOA RHOC RHOGAP1 RHOGAP5 RICS ROCK1 ROCK2 RTKN RTKN1 SF2P32 SLK SOLO STARD12 STARD13 STB2 STK10 STK2 STK21 STOM STX5 STX5A SYB3 TEM4 TFRC TIM TJP2 TMEM57 TMPO VAMP3 VANGL1 VAPB VAV2 WBP3 X104 XTP8 ZO2 p190ARHOGAP
RHOBTB3 ATPase cycle	Cullin-3 G1/S-specific cyclin-E1 Hepatocyte growth factor-regulated tyrosine kinase substrate Leucine-rich repeat-containing protein 41 Perilipin-3 Ras-related protein Rab-9A Ras-related protein Rab-9B Rho-related BTB domain-containing protein 3 von Hippel-Lindau disease tumor suppressor	O14964 O60664 O94955 P24864 P40337 P51151 Q13618 Q15345 Q9NP90	CCNE CCNE1 CUL3 HGS HRS KIAA0617 KIAA0878 LRRC41 M6PRBP1 MUF1 PLIN3 RAB9 RAB9A RAB9B RAB9L RHOBTB3 TIP47 VHL
RHOBTB2 GTPase cycle	Actin, cytoplasmic 2 Alpha-actinin-1 Cullin-3 Drebrin Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heterogeneous nuclear ribonucleoproteins C1/C2 Hsp90 co-chaperone Cdc37 PH-interacting protein RNA-binding motif protein, X chromosome RNA-binding protein Musashi homolog 2 Rho-related BTB domain-containing protein 2 Serine/arginine repetitive matrix protein 1 Serine/threonine-protein kinase 38 Spliceosome RNA helicase DDX39B T-complex protein 1 subunit beta T-complex protein 1 subunit eta T-complex protein 1 subunit zeta Thioredoxin-like protein 1 Transformer-2 protein homolog beta Tropomodulin-3 Twinfilin-1 Unconventional myosin-VI	O43396 P07900 P07910 P08238 P12814 P38159 P40227 P62995 P63261 P78371 Q12792 Q13618 Q13838 Q15208 Q16543 Q16643 Q8IYB3 Q8WWQ0 Q96DH6 Q99832 Q9BYZ6 Q9NYL9 Q9UM54	99D8.1 ACTG ACTG1 ACTN1 BAT1 CCT2 CCT6 CCT6A CCT7 CCTB CCTH CCTZ CDC37 CDC37A CUL3 D0S117E DBC2 DBN1 DCAF14 DDX39B HNRNPC HNRPC HNRPG HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB KIAA0389 KIAA0617 KIAA0717 MSI2 MYO6 NDR1 NIP7-1 PHIP PTK9 RBMX RBMXP1 RHOBTB2 SFRS10 SRM160 SRRM1 STK38 TMOD3 TRA2B TRP32 TWF1 TXL TXNL TXNL1 UAP56 WDR11
RHOBTB1 GTPase cycle	COP9 signalosome complex subunit 1 COP9 signalosome complex subunit 2 COP9 signalosome complex subunit 4 Cleavage and polyadenylation specificity factor subunit 7 Cullin-3 Drebrin E3 ubiquitin-protein ligase BRE1A E3 ubiquitin-protein ligase RBBP6 Heterogeneous nuclear ribonucleoproteins C1/C2 Msx2-interacting protein RNA-binding motif protein, X chromosome Rho-associated protein kinase 1 Rho-associated protein kinase 2 Rho-related BTB domain-containing protein 1 Serine/arginine repetitive matrix protein 1 Serine/threonine-protein kinase 38 T-complex protein 1 subunit beta T-complex protein 1 subunit eta Thioredoxin-like protein 1 Transformer-2 protein homolog beta Unconventional myosin-VI Vimentin cGMP-specific 3',5'-cyclic phosphodiesterase	O43396 O75116 O76074 O94844 P07910 P08670 P38159 P61201 P62995 P78371 Q13098 Q13464 Q13618 Q15208 Q16643 Q5VTR2 Q7Z6E9 Q8IYB3 Q8N684 Q96T58 Q99832 Q9BT78 Q9UM54	99D8.1 BRE1A CCT2 CCT7 CCTB CCTH COPS1 COPS2 COPS4 CPSF7 CSN1 CSN2 CSN4 CUL3 D0S117E DBN1 GPS1 HNRNPC HNRPC HNRPG KIAA0389 KIAA0617 KIAA0619 KIAA0740 KIAA0929 MINT MYO6 NDR1 NIP7-1 P2PR PACT PDE5 PDE5A RBBP6 RBMX RBMXP1 RBQ1 RHOBTB1 RNF20 ROCK1 ROCK2 SFRS10 SHARP SPEN SRM160 SRRM1 STK38 TRA2B TRIP15 TRP32 TXL TXNL TXNL1 VIM
RHOB GTPase cycle	A-kinase anchor protein 13 Actin, alpha cardiac muscle 1 Active breakpoint cluster region-related protein Anillin Ankyrin repeat domain-containing protein SOWAHC Breakpoint cluster region protein Caveolae-associated protein 1 Caveolin-1 Cell surface glycoprotein MUC18 Citron Rho-interacting kinase DEP domain-containing protein 1B Disheveled-associated activator of morphogenesis 1 Erbin Flotillin-1 Flotillin-2 Guanine nucleotide exchange factor DBS Guanine nucleotide exchange factor VAV2 Junction plakoglobin Neuroepithelial cell-transforming gene 1 protein Oligophrenin-1 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Protein ECT2 Protein diaphanous homolog 1 Protein diaphanous homolog 3 Proto-oncogene DBL Protocadherin-7 Rac GTPase-activating protein 1 Ras GTPase-activating-like protein IQGAP3 Rho GDP-dissociation inhibitor 3 Rho GTPase-activating protein 1 Rho GTPase-activating protein 21 Rho GTPase-activating protein 26 Rho GTPase-activating protein 32 Rho GTPase-activating protein 35 Rho GTPase-activating protein 39 Rho GTPase-activating protein 5 Rho GTPase-activating protein 7 Rho guanine nucleotide exchange factor 10-like protein Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 28 Rho guanine nucleotide exchange factor 2 Rho guanine nucleotide exchange factor 3 Rho guanine nucleotide exchange factor 5 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Rho-related GTP-binding protein RhoB Rhophilin-2 Rhotekin STE20-like serine/threonine-protein kinase Serine/threonine-protein kinase 10 Serine/threonine-protein kinase N1 Serine/threonine-protein kinase N2 Serine/threonine-protein kinase N3 StAR-related lipid transfer protein 13 StAR-related lipid transfer protein 8 Stomatin Synaptosomal-associated protein 23 Tight junction protein ZO-2 Transferrin receptor protein 1 Unconventional myosin-IXa Unconventional myosin-IXb Vang-like protein 1 Vesicle-associated membrane protein 3	A7KAX9 B2RTY4 O00161 O00459 O14578 O15013 O15068 O15085 O60245 O60610 O60890 O75116 O75955 O94804 P02786 P10911 P11274 P14923 P27105 P27986 P43121 P52735 P62745 P68032 Q03135 Q07960 Q12774 Q12802 Q12979 Q13017 Q13459 Q13464 Q14254 Q15836 Q16512 Q16513 Q53LP3 Q5T5U3 Q6NZI2 Q6P5Z2 Q7Z628 Q86VI3 Q86VW2 Q8IUC4 Q8N1W1 Q8TAA9 Q8TCU6 Q8WUY9 Q92502 Q92888 Q92974 Q96PE2 Q96QB1 Q96RT1 Q99819 Q9BST9 Q9C0H5 Q9H0H5 Q9H2G2 Q9H8V3 Q9HCE6 Q9NQW6 Q9NR81 Q9NRY4 Q9NSV4 Q9NZN5 Q9UDY2 Q9UNA1 Q9Y3M8 Q9Y4D1	ABR ACTC ACTC1 AKAP13 ANKRD57 ANLN ARH6 ARHB ARHGAP1 ARHGAP10 ARHGAP21 ARHGAP26 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP5 ARHGAP7 ARHGDIG ARHGEF1 ARHGEF10 ARHGEF10L ARHGEF11 ARHGEF12 ARHGEF17 ARHGEF2 ARHGEF25 ARHGEF28 ARHGEF3 ARHGEF5 ARHGEF8 BCR BCR1 BHPCDH BND7 BRX C2orf26 CAV CAV1 CAVIN1 CDC42GAP CIT CRIK CTNNG D22S11 DAAM1 DBL DEPDC1B DIAP1 DIAP3 DIAPH1 DIAPH3 DLC1 DLC2 DLC3 DP3 ECT2 EPB72 ERBB2IP ERBIN ESA1 FLOT1 FLOT2 GEFT GRAF GRB1 GRF1 GRINCHGEF GRIT GRLF1 GT650 HT31 IQGAP3 JUP KIAA0189 KIAA0204 KIAA0294 KIAA0337 KIAA0362 KIAA0380 KIAA0382 KIAA0619 KIAA0621 KIAA0651 KIAA0666 KIAA0712 KIAA0949 KIAA1225 KIAA1415 KIAA1424 KIAA1478 KIAA1626 KIAA1688 KIAA1722 KIAA1723 KIAA1998 LAP2 LARG LBC LFP40 LOK M17S1 MCAM MCF2 MCF2L MGCRACGAP MUC18 MYO9A MYO9B MYR5 MYR7 NET1 OPHN1 OPHN1L OST P190A PAK1 PCDH7 PIK3R1 PIK3R2 PKN PKN1 PKN2 PKN3 PKNBETA PREX1 PRK1 PRK2 PRKCL1 PRKCL2 PTRF RACGAP1 RGNEF RHOB RHOGAP1 RHOGAP5 RHPN2 RICS ROCK1 ROCK2 RTKN RTKN1 SLK SNAP23 SOWAHC STARD12 STARD13 STARD8 STB2 STK10 STK2 STK21 STOM SYB3 TEM4 TFRC TIM TJP2 VAMP3 VANGL1 VAV2 X104 XTP8 ZO2 p190ARHOGAP
RHOA GTPase cycle	A-kinase anchor protein 13 ATP-binding cassette sub-family D member 3 Actin, alpha cardiac muscle 1 Active breakpoint cluster region-related protein Acyl-CoA-binding domain-containing protein 5 Aladin Anillin Ankyrin repeat domain-containing protein SOWAHC Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 B-cell receptor-associated protein 31 Breakpoint cluster region protein Caveolae-associated protein 1 Caveolin-1 Cell surface glycoprotein MUC18 Citron Rho-interacting kinase Coiled-coil domain-containing protein 115 Complement component 1 Q subcomponent-binding protein, mitochondrial DDRGK domain-containing protein 1 DEP domain-containing protein 1B Dedicator of cytokinesis protein 2 Delta(14)-sterol reductase LBR Differentially expressed in FDCP 6 homolog Disheveled-associated activator of morphogenesis 1 ER membrane protein complex subunit 3 Ephexin-1 Erbin FAS-associated factor 2 FERM, ARHGEF and pleckstrin domain-containing protein 1 Flotillin-1 Flotillin-2 Formin-like protein 3 GEM-interacting protein Guanine nucleotide exchange factor DBS Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Heme oxygenase 2 Inactive Rho GTPase-activating protein 11B Junction plakoglobin Kalirin Kinectin Lamina-associated polypeptide 2, isoforms beta/gamma Macoilin Membrane-associated progesterone receptor component 2 Neuroepithelial cell-transforming gene 1 protein Obscurin Oligophrenin-1 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phospholipase D1 Pleckstrin homology domain-containing family G member 3 Pleckstrin homology domain-containing family G member 5 Pleckstrin homology domain-containing family G member 6 Protein ECT2 Protein ERGIC-53 Protein FAM13A Protein diaphanous homolog 1 Protein diaphanous homolog 3 Proto-oncogene DBL Proto-oncogene vav Protocadherin-7 Puratrophin-1 Rac GTPase-activating protein 1 Ras GTPase-activating-like protein IQGAP1 Ras GTPase-activating-like protein IQGAP3 Ras-specific guanine nucleotide-releasing factor 2 Rho GDP-dissociation inhibitor 1 Rho GDP-dissociation inhibitor 2 Rho GTPase-activating protein 10 Rho GTPase-activating protein 11A Rho GTPase-activating protein 18 Rho GTPase-activating protein 19 Rho GTPase-activating protein 1 Rho GTPase-activating protein 20 Rho GTPase-activating protein 21 Rho GTPase-activating protein 22 Rho GTPase-activating protein 23 Rho GTPase-activating protein 24 Rho GTPase-activating protein 26 Rho GTPase-activating protein 28 Rho GTPase-activating protein 29 Rho GTPase-activating protein 30 Rho GTPase-activating protein 31 Rho GTPase-activating protein 32 Rho GTPase-activating protein 35 Rho GTPase-activating protein 39 Rho GTPase-activating protein 40 Rho GTPase-activating protein 42 Rho GTPase-activating protein 44 Rho GTPase-activating protein 45 Rho GTPase-activating protein 4 Rho GTPase-activating protein 5 Rho GTPase-activating protein 6 Rho GTPase-activating protein 7 Rho GTPase-activating protein 8 Rho GTPase-activating protein 9 Rho guanine nucleotide exchange factor 10-like protein Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 18 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 28 Rho guanine nucleotide exchange factor 2 Rho guanine nucleotide exchange factor 3 Rho guanine nucleotide exchange factor 40 Rho guanine nucleotide exchange factor 4 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 7 Rho guanine nucleotide exchange factor TIAM1 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Rhophilin-1 Rhophilin-2 Rhotekin SLIT-ROBO Rho GTPase-activating protein 1 STE20-like serine/threonine-protein kinase Sec1 family domain-containing protein 1 Serine/threonine-protein kinase 10 Serine/threonine-protein kinase N1 Serine/threonine-protein kinase N2 Serine/threonine-protein kinase N3 StAR-related lipid transfer protein 13 StAR-related lipid transfer protein 8 Starch-binding domain-containing protein 1 Stomatin Synaptobrevin homolog YKT6 Synaptosomal-associated protein 23 Syntaxin-5 T-cell activation Rho GTPase-activating protein Testis-expressed protein 2 Tight junction protein ZO-2 Transferrin receptor protein 1 Transforming protein RhoA Transmembrane protein 87A Triple functional domain protein Unconventional myosin-IXa Unconventional myosin-IXb V-type proton ATPase subunit S1 Vang-like protein 1 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein-associated protein B/C	A1A4S6 A1L390 A6NI28 A7KAX9 B2RTY4 O00161 O00459 O14578 O14827 O15013 O15068 O15085 O15173 O15498 O43182 O60229 O60245 O60610 O60890 O75116 O75955 O75962 O94804 O94827 O94988 O94989 O95210 O95292 P02786 P10911 P11274 P14923 P15498 P27105 P27986 P28288 P30519 P42167 P43121 P46940 P49257 P51572 P52565 P52566 P52735 P61586 P68032 P85298 P98171 Q03135 Q07021 Q07960 Q12774 Q12802 Q12979 Q13009 Q13017 Q13190 Q13393 Q13459 Q13464 Q14155 Q14254 Q14739 Q14CB8 Q15836 Q15904 Q16512 Q16513 Q17R89 Q2M1Z3 Q3KR16 Q3KRB8 Q52LW3 Q53LP3 Q58EX7 Q5T5U3 Q5T8D3 Q5TG30 Q5VST9 Q6NZI2 Q6P4F7 Q6P5Z2 Q6ZSZ5 Q70Z35 Q7Z5H3 Q7Z628 Q7Z6B7 Q7Z6I6 Q86UP2 Q86VI3 Q86VW2 Q8IUC4 Q8IVF7 Q8IW93 Q8IWB9 Q8N103 Q8N1W1 Q8N264 Q8N392 Q8N5G2 Q8N5V2 Q8NBN3 Q8TAA9 Q8TCU6 Q8TCX5 Q8TER5 Q8WUY9 Q8WVM8 Q8WWN8 Q8WZ64 Q92502 Q92608 Q92619 Q92888 Q92974 Q96CS3 Q96HY6 Q96NT0 Q96P48 Q96PE2 Q96QB1 Q96RT1 Q9BRR9 Q9BST9 Q9C0H5 Q9H0H5 Q9H2G2 Q9H4E7 Q9H8V3 Q9HCE6 Q9NQW6 Q9NR80 Q9NR81 Q9NRG9 Q9NRY4 Q9NSV4 Q9NZN5 Q9P0I2 Q9P107 Q9P227 Q9P2F6 Q9P2N2 Q9UDY2 Q9UKW4 Q9UNA1 Q9Y3M8 Q9Y4D1 Q9Y4F1	AAAS ABCD3 ABR ACBD5 ACTC ACTC1 ADRACALA AKAP13 ANKRD57 ANLN ARAP1 ARAP2 ARAP3 ARH12 ARHA ARHGAP1 ARHGAP10 ARHGAP11A ARHGAP11B ARHGAP13 ARHGAP18 ARHGAP19 ARHGAP20 ARHGAP21 ARHGAP22 ARHGAP23 ARHGAP24 ARHGAP26 ARHGAP28 ARHGAP29 ARHGAP30 ARHGAP31 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP4 ARHGAP40 ARHGAP42 ARHGAP44 ARHGAP45 ARHGAP5 ARHGAP6 ARHGAP7 ARHGAP8 ARHGAP9 ARHGDIA ARHGDIB ARHGEF1 ARHGEF10 ARHGEF10L ARHGEF11 ARHGEF12 ARHGEF15 ARHGEF17 ARHGEF18 ARHGEF19 ARHGEF2 ARHGEF25 ARHGEF28 ARHGEF3 ARHGEF4 ARHGEF40 ARHGEF5 ARHGEF7 ARHGEF8 ATP6AP1 ATP6IP1 ATP6S1 BAP31 BCAP31 BCR BCR1 BHPCDH BND7 BRX C14orf163 C1QBP C20orf116 C20orf95 C2orf26 CAV CAV1 CAVIN1 CCDC115 CDC42GAP CDEP CDGAP CENTD1 CENTD2 CENTD3 CG1 CIT COOL1 CRIK CTNNG D22S11 DAAM1 DBL DDRGK1 DEF6 DEPDC1B DEPDC2 DG6 DIAP1 DIAP3 DIAPH1 DIAPH3 DLC1 DLC2 DLC3 DOCK2 DP3 DUET DUO DXS1357E ECT2 EMC3 EPB72 ERBB2IP ERBIN ERGIC53 ESA1 ETEA F5F8D FAF2 FAM13A FAM13A1 FAM7B1 FARP1 FHOD3 FILGAP FLOT1 FLOT2 FMNL3 FRL2 GC1QBP GDIA1 GDIA2 GDID4 GEFT GMIP GRAF GRAF2 GRAF3 GRB1 GRF1 GRF2 GRINCHGEF GRIT GRLF1 GT650 HABP1 HAPIP HMHA1 HMOX2 HO2 HT31 IBP IQGAP1 IQGAP3 JUP KALRN KIAA0004 KIAA0013 KIAA0051 KIAA0131 KIAA0142 KIAA0189 KIAA0204 KIAA0209 KIAA0223 KIAA0294 KIAA0337 KIAA0362 KIAA0380 KIAA0382 KIAA0521 KIAA0580 KIAA0599 KIAA0619 KIAA0621 KIAA0651 KIAA0666 KIAA0672 KIAA0712 KIAA0720 KIAA0782 KIAA0887 KIAA0914 KIAA0915 KIAA0917 KIAA0949 KIAA1112 KIAA1204 KIAA1225 KIAA1304 KIAA1314 KIAA1391 KIAA1415 KIAA1424 KIAA1478 KIAA1501 KIAA1556 KIAA1626 KIAA1639 KIAA1688 KIAA1722 KIAA1723 KIAA1738 KIAA1929 KIAA1996 KIAA1998 KIAA2014 KTN1 LAP2 LARG LBC LBR LFP40 LMAN1 LOK M17S1 MACO1 MCAM MCF2 MCF2L MGCRACGAP MUC18 MYO9A MYO9B MYR5 MYR7 NET1 NGEF OBSCN OPHN1 OPHN1L OST P190A P85SPR PAK1 PAK3BP PARG1 PCDH7 PGRMC2 PIK3R1 PIK3R2 PIXB PKN PKN1 PKN2 PKN3 PKNBETA PLD1 PLEKHC2 PLEKHG3 PLEKHG4 PLEKHG5 PLEKHG6 PMBP PMP70 PREX1 PREX2 PRK1 PRK2 PRKCL1 PRKCL2 PRTPHN1 PTRF PXMP1 RACGAP1 RAP1GN1 RASGRF2 RGC1 RGNEF RHO12 RHOA RHOGAP1 RHOGAP2 RHOGAP4 RHOGAP5 RHOGAP6 RHPN1 RHPN2 RICH2 RICS ROCK1 ROCK2 RTKN RTKN1 SCFD1 SF2P32 SLK SNAP23 SOLO SOWAHC SRGAP1 STARD12 STARD13 STARD8 STB2 STBD1 STK10 STK2 STK21 STOM STX5 STX5A STXBP1L2 SYB3 TAGAP TAGAP1 TEM4 TEX2 TFRC TIAM1 TIM TJP2 TMEM111 TMEM133 TMEM57 TMEM87A TMEM96 TMPO TRAD TRIO UBXD8 UBXN3B UFBP1 VAMP3 VANGL1 VAPB VATPS1 VAV VAV1 VAV2 VAV3 WBP3 X104 XAP3 XTP8 YKT6 ZO2 p190ARHOGAP
RHO GTPases regulate CFTR trafficking	Cystic fibrosis transmembrane conductance regulator Golgi-associated PDZ and coiled-coil motif-containing protein Rho-related GTP-binding protein RhoQ	P13569 P17081 Q9HD26	ABCC7 ARHQ CAL CFTR FIG GOPC RASL7A RHOQ TC10
RHO GTPases activate PKNs	14-3-3 protein beta/alpha 14-3-3 protein epsilon 14-3-3 protein eta 14-3-3 protein gamma 14-3-3 protein sigma 14-3-3 protein theta 14-3-3 protein zeta/delta 3-phosphoinositide-dependent protein kinase 1 M-phase inducer phosphatase 3 Myosin light polypeptide 6 Myosin regulatory light chain 12B Myosin regulatory light polypeptide 9 Myosin-10 Myosin-11 Myosin-14 Myosin-9 Protein phosphatase 1 regulatory subunit 12A Protein phosphatase 1 regulatory subunit 12B Protein phosphatase 1 regulatory subunit 14A Ras-related C3 botulinum toxin substrate 1 Rho-related GTP-binding protein RhoB Rho-related GTP-binding protein RhoC Serine/threonine-protein kinase N1 Serine/threonine-protein kinase N2 Serine/threonine-protein kinase N3 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein phosphatase PP1-beta catalytic subunit Transforming protein RhoA	O14950 O14974 O15530 O60237 P08134 P24844 P27348 P30307 P31946 P31947 P35579 P35580 P35749 P60660 P61586 P61981 P62140 P62258 P62745 P63000 P63104 Q04917 Q13153 Q16512 Q16513 Q6P5Z2 Q7Z406 Q96A00	ARH12 ARH6 ARH9 ARHA ARHB ARHC CDC25C CPI17 HME1 KIAA0866 KIAA2034 MBS MLC2 MRLC1 MRLC2 MYH10 MYH11 MYH14 MYH9 MYL12B MYL6 MYL9 MYLC2B MYPT1 MYPT2 MYRL2 PAK1 PDK1 PDPK1 PKN PKN1 PKN2 PKN3 PKNBETA PPP1CB PPP1INL PPP1R12A PPP1R12B PPP1R14A PRK1 PRK2 PRKCL1 PRKCL2 RAC1 RHO12 RHOA RHOB RHOC SFN TC25 YWHA1 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ
RHO GTPases activate PAKs	Calmodulin-1 Cell division control protein 42 homolog Filamin-A LIM domain kinase 1 Merlin Myosin light chain kinase, smooth muscle Myosin light polypeptide 6 Myosin regulatory light chain 12B Myosin regulatory light polypeptide 9 Myosin-10 Myosin-11 Myosin-14 Myosin-9 Protein phosphatase 1 regulatory subunit 12A Protein phosphatase 1 regulatory subunit 12B Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Serine/threonine-protein phosphatase PP1-beta catalytic subunit Src substrate cortactin	O14950 O14974 O60237 O75914 P0DP23 P21333 P24844 P35240 P35579 P35580 P35749 P53667 P60660 P60953 P62140 P63000 Q13153 Q13177 Q14247 Q15746 Q7Z406	CALM CALM1 CAM CAM1 CDC42 CTTN EMS1 FLN FLN1 FLNA KIAA0866 KIAA2034 LIMK LIMK1 MBS MLC2 MLCK MLCK1 MRLC1 MRLC2 MYH10 MYH11 MYH14 MYH9 MYL12B MYL6 MYL9 MYLC2B MYLK MYLK1 MYPT1 MYPT2 MYRL2 NF2 OPHN3 PAK1 PAK2 PAK3 PPP1CB PPP1R12A PPP1R12B RAC1 SCH TC25
RHO GTPases activate KTN1	Cell division control protein 42 homolog Kinectin Kinesin heavy chain isoform 5A Kinesin light chain 1 Kinesin light chain 2 Kinesin light chain 3 Kinesin light chain 4 Kinesin-1 heavy chain Ras-related C3 botulinum toxin substrate 1 Rho-related GTP-binding protein RhoG Transforming protein RhoA	P33176 P60953 P61586 P63000 P84095 Q07866 Q12840 Q6P597 Q86UP2 Q9H0B6 Q9NSK0	ARH12 ARHA ARHG CDC42 CG1 KIAA0004 KIF5A KIF5B KLC KLC1 KLC2 KLC2L KLC3 KLC4 KNS KNS1 KNS2 KNSL8 KTN1 NKHC1 RAC1 RHO12 RHOA RHOG TC25
RHO GTPases activate IQGAPs	CAP-Gly domain-containing linker protein 1 Cadherin-1 Calmodulin-1 Catenin alpha-1 Catenin beta-1 Cell division control protein 42 homolog Menin Ras GTPase-activating-like protein IQGAP1 Ras GTPase-activating-like protein IQGAP2 Ras GTPase-activating-like protein IQGAP3 Ras-related C3 botulinum toxin substrate 1	O00255 P0DP23 P12830 P30622 P35221 P35222 P46940 P60953 P63000 Q13576 Q86VI3	CALM CALM1 CAM CAM1 CDC42 CDH1 CDHE CLIP1 CTNNA1 CTNNB CTNNB1 CYLN1 IQGAP1 IQGAP2 IQGAP3 KIAA0051 MEN1 RAC1 RSN SCG2 TC25 UVO
RHO GTPases activate CIT	Citron Rho-interacting kinase Cyclin-dependent kinase inhibitor 1B Disks large homolog 4 Kinesin-like protein KIF14 Myosin light polypeptide 6 Myosin regulatory light chain 12B Myosin regulatory light polypeptide 9 Myosin-10 Myosin-11 Myosin-14 Myosin-9 Protein phosphatase 1 regulatory subunit 12A Protein phosphatase 1 regulatory subunit 12B Protein regulator of cytokinesis 1 Ras-related C3 botulinum toxin substrate 1 Rho-related GTP-binding protein RhoB Rho-related GTP-binding protein RhoC Serine/threonine-protein phosphatase PP1-beta catalytic subunit Transforming protein RhoA	O14578 O14950 O14974 O43663 O60237 P08134 P24844 P35579 P35580 P35749 P46527 P60660 P61586 P62140 P62745 P63000 P78352 Q15058 Q7Z406	ARH12 ARH6 ARH9 ARHA ARHB ARHC CDKN1B CIT CRIK DLG4 KIAA0042 KIAA0866 KIAA0949 KIAA2034 KIF14 KIP1 MBS MLC2 MRLC1 MRLC2 MYH10 MYH11 MYH14 MYH9 MYL12B MYL6 MYL9 MYLC2B MYPT1 MYPT2 MYRL2 PPP1CB PPP1R12A PPP1R12B PRC1 PSD95 RAC1 RHO12 RHOA RHOB RHOC STK21 TC25 p27
RHO GTPases Activate WASPs and WAVEs	Abl interactor 1 Abl interactor 2 Actin nucleation-promoting factor WAS Actin nucleation-promoting factor WASL Actin, cytoplasmic 1 Actin, cytoplasmic 2 Actin-binding protein WASF1 Actin-binding protein WASF2 Actin-binding protein WASF3 Actin-related protein 2/3 complex subunit 1A Actin-related protein 2/3 complex subunit 1B Actin-related protein 2/3 complex subunit 2 Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2 Actin-related protein 3 BAR/IMD domain-containing adapter protein 2 Cell division control protein 42 homolog Cytoplasmic FMR1-interacting protein 1 Cytoplasmic FMR1-interacting protein 2 Focal adhesion kinase 1 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 NCK-interacting protein with SH3 domain Nck-associated protein 1-like Nck-associated protein 1 Protein BRICK1 Ras-related C3 botulinum toxin substrate 1 SH2/SH3 adapter protein NCK1 Tyrosine-protein kinase ABL1 Tyrosine-protein kinase BTK WAS/WASL-interacting protein family member 1 WAS/WASL-interacting protein family member 2 WAS/WASL-interacting protein family member 3	A6NGB9 O00401 O15143 O15144 O15145 O15511 O43516 P00519 P16333 P27361 P28482 P42768 P55160 P59998 P60709 P60953 P61158 P61160 P63000 P63261 Q05397 Q06187 Q7L576 Q8IZP0 Q8TF74 Q8WUW1 Q92558 Q92747 Q96F07 Q9NYB9 Q9NZQ3 Q9UPY6 Q9UQB8 Q9Y2A7 Q9Y6W5	ABI1 ABI2 ABL ABL1 ACTB ACTG ACTG1 ACTR2 ACTR3 AF3P21 AGMX1 ARC16 ARC20 ARC21 ARC34 ARC41 ARGBPIA ARP2 ARP3 ARPC1A ARPC1B ARPC2 ARPC3 ARPC4 ARPC5 ATK BAIAP2 BPK BRK1 BTK C3orf10 CDC42 CR16 CYFIP1 CYFIP2 ERK1 ERK2 FAK FAK1 HEM1 HEM2 IMD2 JTK7 KIAA0068 KIAA0269 KIAA0587 KIAA0900 KIAA1168 MAPK1 MAPK3 NAP1 NCK NCK1 NCKAP1 NCKAP1L NCKIPSD PIR121 PRKM1 PRKM2 PRKM3 PTK2 RAC1 SCAR1 SCAR3 SOP2L SPIN90 SSH3BP1 TC25 WAS WASF1 WASF2 WASF3 WASL WASPIP WAVE1 WAVE2 WAVE3 WICH WIP WIPF1 WIPF2 WIPF3 WIRE
RHO GTPases Activate Rhotekin and Rhophilins	Protein lin-7 homolog B Rho-related GTP-binding protein RhoB Rho-related GTP-binding protein RhoC Rhophilin-1 Rhophilin-2 Rhotekin Ropporin-1A Tax1-binding protein 3 Transforming protein RhoA	O14907 P08134 P61586 P62745 Q8IUC4 Q8TCX5 Q9BST9 Q9HAP6 Q9HAT0	ARH12 ARH6 ARH9 ARHA ARHB ARHC KIAA1929 LIN7B MALS2 RHO12 RHOA RHOB RHOC RHPN1 RHPN2 ROPN1 ROPN1A RTKN RTKN1 TAX1BP3 TIP1 VELI2
RHO GTPases Activate ROCKs	Cofilin-1 LIM domain kinase 1 LIM domain kinase 2 Myosin light polypeptide 6 Myosin regulatory light chain 12B Myosin regulatory light polypeptide 9 Myosin-10 Myosin-11 Myosin-14 Myosin-9 Protein phosphatase 1 regulatory subunit 12A Protein phosphatase 1 regulatory subunit 12B Rho-associated protein kinase 1 Rho-associated protein kinase 2 Rho-related GTP-binding protein RhoB Rho-related GTP-binding protein RhoC Serine/threonine-protein kinase PAK 1 Serine/threonine-protein phosphatase PP1-beta catalytic subunit Transforming protein RhoA	O14950 O14974 O60237 O75116 P08134 P23528 P24844 P35579 P35580 P35749 P53667 P53671 P60660 P61586 P62140 P62745 Q13153 Q13464 Q7Z406	ARH12 ARH6 ARH9 ARHA ARHB ARHC CFL CFL1 KIAA0619 KIAA0866 KIAA2034 LIMK LIMK1 LIMK2 MBS MLC2 MRLC1 MRLC2 MYH10 MYH11 MYH14 MYH9 MYL12B MYL6 MYL9 MYLC2B MYPT1 MYPT2 MYRL2 PAK1 PPP1CB PPP1R12A PPP1R12B RHO12 RHOA RHOB RHOC ROCK1 ROCK2
RHO GTPases Activate NADPH Oxidases	Cytochrome b-245 heavy chain Cytochrome b-245 light chain Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 14 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 NADPH oxidase 1 NADPH oxidase 3 NADPH oxidase activator 1 NADPH oxidase organizer 1 Neutrophil cytosol factor 1 Neutrophil cytosol factor 2 Neutrophil cytosol factor 4 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphoinositide 3-kinase regulatory subunit 4 Protein S100-A8 Protein S100-A9 Protein kinase C alpha type Protein kinase C beta type Protein kinase C delta type Protein kinase C zeta type Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 2	P04839 P05109 P05771 P06702 P13498 P14598 P15153 P17252 P19878 P27361 P28482 P63000 Q05513 Q05655 Q13526 Q15080 Q15759 Q16539 Q86UR1 Q8NEB9 Q8NFA2 Q99570 Q9HBY0 Q9Y5S8	CAGA CAGB CFAG CSBP CSBP1 CSBP2 CSPB1 CYBA CYBB ERK1 ERK2 MAPK1 MAPK11 MAPK14 MAPK3 MOX1 MOX2 MRP14 MRP8 MXI2 NCF1 NCF2 NCF4 NOH1 NOX1 NOX2 NOX3 NOXA1 NOXA2 NOXO1 NOXO2 P41NOX P51NOX P67PHOX PIK3C3 PIK3R4 PIN1 PKC2 PKCA PKCB PKCD PRKACA PRKCA PRKCB PRKCB1 PRKCD PRKCZ PRKM1 PRKM11 PRKM2 PRKM3 RAC1 RAC2 S100A8 S100A9 SAPK2 SAPK2A SAPK2B SH3PXD1A SH3PXD4 SH3PXD5 TC25 VPS15 VPS34
RHO GTPases Activate Formins	Actin, cytoplasmic 1 Actin, cytoplasmic 2 Aurora kinase B B9 domain-containing protein 2 Baculoviral IAP repeat-containing protein 5 Borealin CAP-Gly domain-containing linker protein 1 CLIP-associating protein 1 CLIP-associating protein 2 Cell division control protein 42 homolog Cell division cycle protein 20 homolog Centromere protein C Centromere protein F Centromere protein H Centromere protein I Centromere protein K Centromere protein L Centromere protein M Centromere protein N Centromere protein O Centromere protein P Centromere protein Q Centromere protein R Centromere protein S Centromere protein T Centromere protein U Centromere-associated protein E Centromere/kinetochore protein zw10 homolog Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 Cytoskeleton-associated protein 5 DNA excision repair protein ERCC-6-like Disheveled-associated activator of morphogenesis 1 Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic E3 SUMO-protein ligase RanBP2 Ena/VASP-like protein Exportin-1 Formin-like protein 1 Formin-like protein 2 Formin-like protein 3 Histone H3-like centromeric protein A Inner centromere protein Integrin beta-1 Kinesin-like protein KIF18A Kinesin-like protein KIF2A Kinesin-like protein KIF2B Kinesin-like protein KIF2C Kinetochore protein NDC80 homolog Kinetochore protein Nuf2 Kinetochore protein Spc24 Kinetochore protein Spc25 Kinetochore scaffold 1 Kinetochore-associated protein 1 Kinetochore-associated protein DSN1 homolog Kinetochore-associated protein NSL1 homolog Microtubule-associated protein RP/EB family member 1 Mitotic checkpoint protein BUB3 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Mitotic checkpoint serine/threonine-protein kinase BUB1 Mitotic spindle assembly checkpoint protein MAD1 Mitotic spindle assembly checkpoint protein MAD2A Myocardin-related transcription factor A Nuclear distribution protein nudE homolog 1 Nuclear distribution protein nudE-like 1 Nuclear migration protein nudC Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup85 Nucleoporin Nup37 Nucleoporin Nup43 Platelet-activating factor acetylhydrolase IB subunit beta Polyamine-modulated factor 1 Profilin-1 Profilin-2 Protein ELYS Protein MIS12 homolog Protein RCC2 Protein SCAI Protein SEC13 homolog Protein Spindly Protein diaphanous homolog 1 Protein diaphanous homolog 3 Protein zwilch homolog Ran GTPase-activating protein 1 Ras-related C3 botulinum toxin substrate 1 Rho-related GTP-binding protein RhoB Rho-related GTP-binding protein RhoC Rho-related GTP-binding protein RhoD SLIT-ROBO Rho GTPase-activating protein 2 Segment polarity protein dishevelled homolog DVL-1 Segment polarity protein dishevelled homolog DVL-2 Segment polarity protein dishevelled homolog DVL-3 Serine/threonine-protein kinase PLK1 Serine/threonine-protein kinase TAO1 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Serum response factor Shugoshin 1 Shugoshin 2 Small ribosomal subunit protein eS27 Spindle and kinetochore-associated protein 1 Spindle and kinetochore-associated protein 2 Transforming protein RhoA ZW10 interactor	O00139 O00212 O14576 O14640 O14641 O14777 O14980 O15392 O43237 O43264 O43683 O43684 O60566 O60610 O75044 O75122 O95229 O95466 P05556 P07737 P08134 P11831 P30153 P30154 P30622 P35080 P36873 P42677 P43034 P46060 P49450 P49454 P49792 P50748 P53350 P55735 P57740 P60709 P60953 P61586 P62714 P62745 P63000 P63167 P63261 P67775 Q02224 Q03188 Q12769 Q12834 Q13257 Q13352 Q13362 Q13409 Q14008 Q14204 Q14738 Q15172 Q15173 Q15691 Q16537 Q2NKX8 Q53HL2 Q562F6 Q5FBB7 Q6IPU0 Q6P1K2 Q71F23 Q7L2Z9 Q7L7X3 Q7Z460 Q8IVF7 Q8N0S6 Q8N2Z9 Q8N4N8 Q8N9R8 Q8NBT2 Q8NFH3 Q8NFH4 Q8NG31 Q8NI77 Q8WUM0 Q8WVK7 Q8WYP5 Q92674 Q92997 Q969V6 Q96BD8 Q96BT3 Q96EA4 Q96FJ2 Q96GD4 Q96H22 Q96IY1 Q96PY5 Q99661 Q9BPU9 Q9BS16 Q9BU64 Q9BW27 Q9BZD4 Q9GZM8 Q9H081 Q9H3R5 Q9H410 Q9H900 Q9HBM1 Q9NQS7 Q9NSP4 Q9NSV4 Q9NXR1 Q9P258 Q9UI08 Q9Y266 Q9Y4D1 Q9Y6D9 Q9Y6G9	ACTB ACTG ACTG1 AHCTF1 AIK2 AIM1 AIRK2 API4 APITD1 ARH12 ARH6 ARH9 ARHA ARHB ARHC ARHD ARHGAP34 ARK2 AURKB B9D2 BIRC5 BUB1 BUB1B BUB1L BUB3 BUBR1 C16orf56 C16orf60 C17orf1 C17orf1B C18orf24 C1orf155 C1orf48 C20orf172 C22orf18 C6orf139 C9orf126 CASC5 CCDC99 CDC20 CDC42 CDCA1 CDCA8 CENPA CENPC CENPC1 CENPE CENPF CENPH CENPI CENPK CENPL CENPM CENPN CENPO CENPP CENPQ CENPR CENPS CENPT CENPU CKAP5 CLASP1 CLASP2 CLIP1 CRM1 CYLN1 D3S1231E DAAM1 DHC1 DIAP1 DIAP3 DIAPH1 DIAPH3 DLC1 DLC2 DNCH1 DNCI1 DNCI2 DNCIC1 DNCIC2 DNCL DNCL1 DNCLC1 DNCLI1 DNCLI2 DNECL DSN1 DVL1 DVL2 DVL3 DYHC DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 ELYS EOPA ERCC6L EVL FAAP16 FAM33A FHOD2 FHOD3 FMNL FMNL1 FMNL2 FMNL3 FNBP2 FNRB FRL1 FRL2 FSHPRH1 HDLC1 HEC HEC1 IAP4 ICEN19 ICEN22 ICEN24 ICEN32 ICEN33 ICEN35 ICEN36 ICEN37 ICEN39 ICEN7 INCENP ITGB1 ITGB3BP KIAA0044 KIAA0097 KIAA0166 KIAA0197 KIAA0208 KIAA0325 KIAA0456 KIAA0622 KIAA0627 KIAA0666 KIAA1361 KIAA1438 KIAA1470 KIAA1570 KIAA1835 KIAA1902 KIAA2014 KIF18A KIF2 KIF2A KIF2B KIF2C KLIP1 KNL1 KNS2 KNSL6 KNTC1 KNTC2 LIC2 LIS1 LRPR1 MAD1 MAD1L1 MAD2 MAD2L1 MAD3L MAL MAP3K16 MAPRE1 MARKK MAST1 MCM21R MDCR MDF2 MDS MHF1 MIS12 MIS13 MITAP1 MKL1 MKSR2 MLF1IP MPS1 MRTFA MSK12 NDC80 NDE1 NDEL1 NRIF3 NSL1 NUDC NUDE NUDEL NUF2 NUF2R NUP107 NUP120 NUP133 NUP160 NUP358 NUP37 NUP43 NUP75 NUP85 PAFAH1B1 PAFAHA PANE1 PBIP1 PCNT1 PESCRG3 PFN1 PFN2 PICH PLK PLK1 PMF1 PPP1CC PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E RAC1 RANBP2 RANGAP1 RCC2 RHO12 RHOA RHOB RHOC RHOD RNB6 RPS27 RSN SCAI SD SEC13 SEC13A SEC13L1 SEC13R SGO1 SGO2 SGOL1 SGOL2 SKA1 SKA2 SPBC24 SPBC25 SPC24 SPC25 SPDL1 SRF SRGAP2 SRGAP2A SSK1 STK1 STK12 STK5 TAOK1 TC25 TD60 TMBS62 TXBP181 WBP3 XPO1 ZW10 ZWILCH ZWINT
RET signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Artemin Docking protein 1 Docking protein 2 Docking protein 4 Docking protein 5 Docking protein 6 Fibroblast growth factor receptor substrate 2 GDNF family receptor alpha-1 GDNF family receptor alpha-2 GDNF family receptor alpha-3 GDNF family receptor alpha-4 GRB2-associated-binding protein 1 GRB2-associated-binding protein 2 Glial cell line-derived neurotrophic factor Growth factor receptor-bound protein 10 Growth factor receptor-bound protein 7 Insulin receptor substrate 2 Mitogen-activated protein kinase 7 Neurturin PDZ and LIM domain protein 7 Persephin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Protein kinase C alpha type Proto-oncogene tyrosine-protein kinase receptor Ret Rap1 GTPase-activating protein 1 SH3 and multiple ankyrin repeat domains protein 3 SHC-transforming protein 1 SHC-transforming protein 3 Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	O00329 O00451 O00459 O60496 O60542 O60609 P07949 P17252 P17612 P19174 P22612 P22694 P27986 P29353 P39905 P42336 P42338 P47736 P56159 Q06124 Q07889 Q13164 Q13322 Q13480 Q14451 Q5T4W7 Q6PKX4 Q8TEW6 Q8WU20 Q92529 Q92569 Q99704 Q99748 Q9BYB0 Q9GZZ7 Q9NR12 Q9P104 Q9UQC2 Q9Y4H2	ARTN BMK1 C20orf180 CDHF12 CDHR16 DOK1 DOK2 DOK4 DOK5 DOK5L DOK6 ENIGMA ERK5 EVN FRS2 GAB1 GAB2 GDNF GDNFRA GDNFRB GFRA1 GFRA2 GFRA3 GFRA4 GRB1 GRB10 GRB7 GRBIR IRS2 KIAA0207 KIAA0474 KIAA0571 KIAA1650 MAPK7 NRTN NSHC PDLIM7 PIK3C1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PKACA PKCA PLC1 PLCG1 PRKACA PRKACB PRKACG PRKCA PRKM7 PROSAP2 PSAP2 PSPN PTC PTP2C PTPN11 RAP1GA1 RAP1GAP RET RETL1 RETL2 SHANK3 SHC SHC1 SHC3 SHCA SHCC SHPTP2 SOS1 TRNR1 TRNR2
RAS signaling downstream of NF1 loss-of-function variants	GTPase HRas GTPase NRas Neurofibromin Sprouty-related, EVH1 domain-containing protein 1 Sprouty-related, EVH1 domain-containing protein 2 Sprouty-related, EVH1 domain-containing protein 3	P01111 P01112 P21359 Q2MJR0 Q7Z698 Q7Z699	EVE-3 HRAS HRAS1 NF1 NRAS SPRED1 SPRED2 SPRED3
RAS processing	ADP-ribosylation factor-like protein 2 Acyl-protein thioesterase 1 Alpha/beta hydrolase domain-containing protein 17A Alpha/beta hydrolase domain-containing protein 17B Alpha/beta hydrolase domain-containing protein 17C Bcl-2-like protein 1 CAAX prenyl protease 2 Calmodulin-1 GTPase HRas GTPase KRas GTPase NRas Golgin subfamily A member 7 Palmitoyltransferase ZDHHC9 Protein farnesyltransferase subunit beta Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha Protein kinase C theta type Protein-S-isoprenylcysteine O-methyltransferase Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta Ubiquitin carboxyl-terminal hydrolase 17 cGMP-dependent protein kinase 2	O43924 O60725 O75608 P01111 P01112 P01116 P0DP23 P36404 P49354 P49356 Q04759 Q07817 Q13237 Q5VST6 Q6PCB6 Q6R6M4 Q7Z5G4 Q96GS6 Q9Y256 Q9Y397	ABHD17A ABHD17B ABHD17C APT1 ARL2 BCL2L BCL2L1 BCLX C19orf27 C9orf77 CALM CALM1 CAM CAM1 CXorf11 DUB3 FACE2 FAM108A1 FAM108B1 FAM108C1 FNTA FNTB GCP16 GOLGA7 HRAS HRAS1 ICMT KRAS KRAS2 LPL1 LYPLA1 NRAS PCCMT PDE6D PDED PRKCQ PRKCT PRKG2 PRKGR2 RASK2 RCE1 RCE1A RCE1B USP17 USP17H USP17I USP17J USP17K USP17L USP17L2 USP17M ZDHHC10 ZDHHC9 ZNF379 ZNF380
RAF/MAP kinase cascade	Alpha-actinin-2 Amphiregulin Angiopoietin-1 receptor Angiopoietin-1 Artemin Astrocytic phosphoprotein PEA-15 Beta-klotho Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Cytokine receptor common subunit beta Cytokine receptor common subunit gamma Disks large homolog 1 Disks large homolog 2 Disks large homolog 3 Disks large homolog 4 Epidermal growth factor receptor Epigen Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 19 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 Fms-related tyrosine kinase 3 ligand Focal adhesion kinase 1 GDNF family receptor alpha-1 GDNF family receptor alpha-2 GDNF family receptor alpha-3 GDNF family receptor alpha-4 GTPase HRas GTPase NRas Glial cell line-derived neurotrophic factor Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2B Glutamate receptor ionotropic, NMDA 2D Granulocyte-macrophage colony-stimulating factor receptor subunit alpha Granulocyte-macrophage colony-stimulating factor Hepatocyte growth factor receptor Hepatocyte growth factor Insulin receptor substrate 1 Insulin receptor substrate 2 Interleukin-2 receptor subunit alpha Interleukin-2 receptor subunit beta Interleukin-2 Interleukin-3 receptor subunit alpha Interleukin-3 Interleukin-5 receptor subunit alpha Interleukin-5 Leucine-rich repeat-containing protein 7 Mast/stem cell growth factor receptor Kit Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Neural cell adhesion molecule 1 Neurofilament light polypeptide Neurturin Persephin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit B Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase receptor Ret Protransforming growth factor alpha RAS guanyl-releasing protein 1 RAS guanyl-releasing protein 4 Ral guanine nucleotide dissociation stimulator-like 1 Ral guanine nucleotide dissociation stimulator-like 2 Ral guanine nucleotide dissociation stimulator-like 3 Ral guanine nucleotide dissociation stimulator Ran-binding protein 9 Rap guanine nucleotide exchange factor 2 Ras guanyl-releasing protein 3 Ras-GEF domain-containing family member 1A Ras-specific guanine nucleotide-releasing factor 1 Ras-specific guanine nucleotide-releasing factor 2 Receptor tyrosine-protein kinase erbB-2 Receptor-type tyrosine-protein kinase FLT3 Receptor-type tyrosine-protein phosphatase alpha SHC-transforming protein 1 SHC-transforming protein 2 SHC-transforming protein 3 Son of sevenless homolog 1 Spectrin alpha chain, erythrocytic 1 Spectrin alpha chain, non-erythrocytic 1 Spectrin beta chain, erythrocytic Spectrin beta chain, non-erythrocytic 1 Spectrin beta chain, non-erythrocytic 2 Spectrin beta chain, non-erythrocytic 4 Spectrin beta chain, non-erythrocytic 5 Tyrosine-protein kinase Fyn Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase JAK3	O00451 O00459 O14511 O14827 O14944 O15020 O15211 O15399 O15520 O43320 O43559 O60542 O60609 O60674 O76093 O95267 O95750 P00533 P01111 P01112 P01127 P01133 P01135 P01589 P02549 P04141 P04626 P05113 P05230 P06241 P07196 P07949 P08581 P08620 P08700 P09038 P09619 P0DP23 P10721 P10767 P11277 P11487 P13591 P14210 P14784 P15509 P15514 P16234 P18433 P21781 P22455 P23458 P26951 P27361 P27986 P28482 P29353 P31371 P31785 P32927 P35070 P35568 P35609 P36888 P39905 P42336 P42338 P49771 P52333 P56159 P56975 P60568 P78352 P98077 Q01082 Q01344 Q02297 Q02763 Q05397 Q05586 Q07889 Q12959 Q12967 Q13224 Q13554 Q13555 Q13557 Q13813 Q13972 Q15121 Q15389 Q15700 Q3MIN7 Q5T4W7 Q6UW88 Q86Z14 Q8IV61 Q8N9B8 Q8TDF6 Q8WU20 Q8WWG1 Q92529 Q92796 Q96NW7 Q96S59 Q99075 Q99748 Q9GZV9 Q9GZZ7 Q9H254 Q9HCT0 Q9NP95 Q9NRC6 Q9NZL6 Q9UQM7 Q9Y4G8 Q9Y4H2	ACTN2 ANGPT1 AREG AREGB ARTN BSPECV BTC CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CD135 CDC25 CDHF12 CDHR16 CSF2 CSF2R CSF2RA CSF2RB CSF2RY DLG1 DLG2 DLG3 DLG4 DTR DTS EGF EGFR EPGN ERBB ERBB1 ERBB2 EREG ERK1 ERK2 EVN FAK FAK1 FGF1 FGF10 FGF16 FGF18 FGF19 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB FGFR4 FLK2 FLT3 FLT3LG FRS2 FRS3 FYN GDNF GDNFRA GDNFRB GFRA1 GFRA2 GFRA3 GFRA4 GGF GMCSF GNRP GRB1 GRF1 GRF2 GRIN1 GRIN2B GRIN2D GRP3 GluN2D HBEGF HEGFL HER1 HER2 HGF HGL HPTA HRAS HRAS1 HRGA HST HST2 HSTF1 HSTF2 HUBSPECV HUSPECV HYPF IL15RB IL2 IL2RA IL2RB IL2RG IL3 IL3R IL3RA IL3RB IL5 IL5R IL5RA IL5RB INT2 IRS1 IRS2 JAK1 JAK1A JAK1B JAK2 JAK3 JTK2 KGF KIAA0003 KIAA0302 KIAA0313 KIAA0846 KIAA0959 KIAA0968 KIAA1232 KIAA1308 KIAA1365 KIAA1642 KIT KLB KS3 LAP1 LRRC7 MAPK1 MAPK3 MET MLN19 NCAM NCAM1 NDF NEAS NEFL NEU NF68 NFL NGL NMDAR1 NMDAR2B NMDAR2D NRAPGEP NRAS NRG1 NRG2 NRG3 NRG4 NRTN NSHC NTAK PDGF2 PDGFB PDGFR PDGFR1 PDGFR2 PDGFRA PDGFRB PDZGEF1 PEA15 PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 PRKM1 PRKM2 PRKM3 PSD95 PSPN PTC PTK2 PTPA PTPRA PTPRL2 RAB2L RALGDS RANBP9 RANBPM RAPGEF2 RASGEF1A RASGRF1 RASGRF2 RASGRP RASGRP1 RASGRP3 RASGRP4 RET RETL1 RETL2 RGF RGL RGL1 RGL2 RGL3 RHEPDGFRA SCA5 SCFR SCK SDGF SHC SHC1 SHC2 SHC3 SHCA SHCB SHCC SIS SMDF SOS1 SPTA SPTA1 SPTA2 SPTAN1 SPTB SPTB1 SPTB2 SPTBN1 SPTBN2 SPTBN3 SPTBN4 SPTBN5 STK1 TEK TGFA TIE2 TKF TRNR1 TRNR2 VMCM VMCM1

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