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GlyCosmos Diseases

List of diseases involving glycan related genes. The information of each database of Glyco-Disease Genes Database (GDGDB) and Alliance of Genome Resources is integrated into one list.

Source	Last Updated
Alliance of Genome Resources	October 9, 2024
Glyco-Disease Genes Database (GDGDB)	January 25, 2017

Displaying entries **15701 - 15725** of **15957** in total

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Disease ID	Disease Name	Gene Symbol	Gene ID ▼	Organism	Source
DOID:2741	bilirubin metabolic disorder Aliases: hereditary hyperbilirubinemia hyperbilirubinemia	ugt1a1 ugt1a6	100135191 100489505	Xenopus tropicalis (tropical clawed frog)	Alliance of Genome Resources
DOID:7998	hyperthyroidism Aliases: overactive thyroid	cs ugt1a1 ugt1a6	100135191 100489505 550067	Xenopus tropicalis (tropical clawed frog)	Alliance of Genome Resources
DOID:8692	myeloid leukemia Aliases: Non-Lymphocytic Leukemia leukaemia myelogenous leukemia myelogenous myeloid granulocytic leukaemia myeloid granulocytic leukemia myeloid leukaemia	fgfr1 ugt1a1 ugt1a6	100135191 100489505 548648	Xenopus tropicalis (tropical clawed frog)	Alliance of Genome Resources
DOID:8778	Crohn's disease Aliases: Crohn disease Crohn's disease of colon Crohn's disease of large bowel Granulomatous Colitis Pediatric Crohn's disease	pon2 ugt1a1 ugt1a6	100135191 100489505 448598	Xenopus tropicalis (tropical clawed frog)	Alliance of Genome Resources
DOID:1612	breast cancer Aliases: breast tumor malignant neoplasm of breast malignant tumor of the breast mammary cancer mammary tumor primary breast cancer	ace pon2 ugt1a1 ugt1a6	100135191 100144634 100489505 448598	Xenopus tropicalis (tropical clawed frog)	Alliance of Genome Resources
DOID:9352	type 2 diabetes mellitus Aliases: NIDDM insulin resistance non-insulin-dependent diabetes mellitus type 2 diabetes type II diabetes mellitus	ace cadm2 nog ogt pon2 ppp1cc ugt1a1 ugt1a6	100135191 100144634 100489505 407879 448238 448598 493191 553157	Xenopus tropicalis (tropical clawed frog)	Alliance of Genome Resources
DOID:9744	type 1 diabetes mellitus Aliases: IDDM insulin-dependent diabetes mellitus type I diabetes mellitus	ace pon2 ugt1a1 ugt1a6 xylt1	100135191 100144634 100145490 100489505 448598	Xenopus tropicalis (tropical clawed frog)	Alliance of Genome Resources
DOID:0060419	chromosome 3q29 microdeletion syndrome Aliases: 3q subtelomere deletion syndrome 3q29 microdeletion syndrome 3q29 recurrent deletion 3qter deletion	slc51al	100135183	Xenopus tropicalis (tropical clawed frog)	Alliance of Genome Resources
DOID:2377	multiple sclerosis Aliases: Generalized multiple sclerosis insular sclerosis	A2M ACAN ACHE ADIPOQ AGER AGT APOA1 APOC2 B4GALT5 B4GALT6 BDNF CACNA1B CCL1 CCL2 CCL5 CCL7 CCR3 CCR5 CD24 CD28 CD40 CD46 CD86 CIITA CLEC16A COL1A1 CTLA4 CTSB EDN1 FAS FASLG FCGR2A FCGR3A GABRA3 GC GLI1 GRM8 GRN H6PD HDAC1 HLA-DPB1 HLA-DQA1 HLA-DQB1 HLA-DRA HLA-DRB1 HLA-DRB3 HSP90AB1 HSPA8 IFNB1 IFNG IGF2 IL13 IL17A IL21R IL23R IL2RA IL4 IL4R IL6 IRF5 JAG1 KIF1B LRCH1 MAG MBP MMP12 MMP9 MOG MPHOSPH9 NECTIN2 NEFH NEFL NGFR NOTCH4 PDCD1 PHACTR2 PLA2G7 PRF1 PTPRC RGMA RHOA SHH SLC11A1 SPP1 TLR4 TNF TNFRSF1A	100133941 10198 1232 1234 1277 149233 1493 1508 176 177 182 183 1906 2 2212 2214 23095 23143 23274 2556 2638 2735 2896 2918 3065 3115 3117 3119 3122 3123 3125 3312 3326 335 344 3456 3458 3481 355 3559 356 3565 3566 3569 3596 3605 3663 387 4099 4155 4179 4261 43 4318 4321 4340 4744 4747 4804 4855 50615 5133 5551 56963 5788 5819 627 6346 6347 6352 6354 6469 6556 6696 7099 7124 7132 774 7941 9331 9334 9370 940 942 9563 958 9749	Homo sapiens (human)	Alliance of Genome Resources
DOID:0112106	chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia Aliases: X-linked dominant chondrodysplasia, Chassaing-Lacombe type X-linked dominant chondrodysplasia-hydrocephaly-microphthalmia syndrome	HDAC6	10013	Homo sapiens (human)	Alliance of Genome Resources
DOID:4947	cholangiocarcinoma Aliases: adult primary Cholangiocarcinoma adult primary cholangiocellular carcinoma cholangiosarcoma	ABCC2 ADRB2 ALB ALOX5 ANXA2 APC APOA1 ASPH EPO EPOR EZH2 FASLG FSCN1 GNAS HDAC6 HGF IL1R2 IL4R IL6 INS KIT KRT7 MDM2 MET MFSD4A MGMT MKI67 MMP2 MMP9 MUC16 MUC1 MUC2 MUC3A MUC4 MUC5AC MUC5B MUC6 NCAM1 NOS2 NOTCH1 OGG1 OSBP2 OSBPL7 PANX2 PAWR PPIA PPP3CA PREX2 PRSS2 PRSS56 PTGS2 REG1A RNF43 RUNX3 SLC4A4 SLC7A5 SOCS3 SOX2 TGFB1 TGFBR2 THBS1 TNC TNFAIP3 TTR UGT1A9 WDHD1 WNT9A	10013 11169 114881 1244 148808 154 2056 2057 213 2146 23762 240 2778 302 3082 324 335 3371 356 3566 3569 3630 3815 3855 4193 4233 4255 4288 4313 4318 444 4582 4583 4584 4585 4586 4588 4684 4843 4851 4968 5074 54600 5478 54894 5530 5645 56666 5743 5967 646960 6624 6657 7040 7048 7057 7128 7276 727897 7483 7850 80243 8140 864 8671 9021 94025	Homo sapiens (human)	Alliance of Genome Resources
DOID:8991	cervix uteri carcinoma in situ Aliases: CIN III CIN III - carcinoma in situ of cervix CIN III - severe dyskaryosis Cervix Ca in situ Severe Dysplasia of the Cervix Uteri Severe dysplasia of cervix carcinoma in situ of cervix carcinoma in situ of uterine cervix carcinoma of cervix stage 0 cervical intraepithelial neoplasia grade III with severe dysplasia squamous intraepithelial neoplasia, grade III	ADAM9 BRCA1 CADM1 CD274 CD46 CDH1 CDKN1B CSF1R CTNNA1 DLG1 FASLG HDAC1 HDAC2 HDAC6 HLA-DRB1 IGFBP3 MLH1 MMP2 MSH2 PDCD1 PHB1 PTEN PTGS2 RB1 RELA SKP2 STAT3 TERT TLR9 TOP2A VEGFA XIAP	10013 1027 1436 1495 1739 23705 29126 3065 3066 3123 331 3486 356 4179 4292 4313 4436 5133 5245 54106 5728 5743 5925 5970 6502 672 6774 7015 7153 7422 8754 999	Homo sapiens (human)	Alliance of Genome Resources
DOID:0080322	polycystic kidney disease	AGT ATF1 C9 CFB CTSB CTSH DLL4 EPAS1 GANAB GNAS GPBAR1 HDAC6 HIF1A KIF3A MTOR MYC NOS3 NPPB PKD1 PKD2 PLA2G4A PPARG PTGS1 PTGS2 PTMA SOD1 STAM2 TNC XYLT2	10013 10254 11127 1508 1512 151306 183 2034 23193 2475 2778 3091 3371 4609 466 4846 4879 5310 5311 5321 54567 5468 5742 5743 5757 629 64132 6647 735	Homo sapiens (human)	Alliance of Genome Resources
DOID:9970	obesity	AACS ABCA1 ABCG5 ABCG8 ACACB ACAT1 ACE ACOX1 ACSL1 ADAMTS20 ADAMTS4 ADAMTS8 ADAMTS9 ADIPOQ ADM ADORA1 ADRB2 ADRB3 AGER AGT AHSG AKR1C1 AKR1C2 AKT2 ALDH1A1 ALDH1A2 ALDH1B1 ALDH2 ALMS1 ALOX12 AMH ANGPTL6 ANKRD26 AOC3 APOA1 APOA2 APOB APOC2 APOC3 APOD APOE APP AR ASIP ATP4B ATP5F1B ATP5F1C AZGP1 B2M BAD BBS2 BDNF BMP5 BMP6 BMP7 BMP8A BMP8B C3 C5AR1 CADM2 CANX CAPN10 CAPN3 CCKAR CCL2 CCL5 CCL7 CCR3 CD36 CD40 CD40LG CDKN1B CNR1 COL1A1 COL3A1 COL4A1 COMT CORO7 CPB2 CPE CPS1 CPT1A CRHBP CRHR1 CTNNB1 CTSC CYP27B1 CYP2B6 CYP2E1 CYP2R1 DCHS1 DCHS2 DCN DEFB1 DEGS1 DEGS2 DGAT1 DNAH10 DRD1 DRD2 DRD4 EDN1 EIF6 ENPP1 ESR1 ETV1 F2 F7 FADD FADS1 FAT4 FGFR1 FGG FJX1 FOXO3 FTO G6PD GABRA6 GAL GALR1 GAPDH GCK GFPT1 GHRL GHSR GIPR GLP1R GLRX GLUL GNAS GNL3 GNRHR GORASP2 GPAM GPR12 GPX1 GPX3 GSTM2 GUCY2C HADH HDAC4 HDAC6 HFE HGF HIF1A HK1 HK2 HMGCS1 HP HPR HRH3 HSD11B1 HSD11B2 HSD17B12 HSD17B3 HSD17B4 HSPA1B HTR1B HTR2A HTR2C ICAM1 IFNG IGF1R IGFBP2 IGFBP3 IGFBP6 IL10 IL15 IL1RN IL3 IL6 IL6R INPP5E INPPL1 IRS1 ITGAM ITIH4 ITPR1 ITPR2 ITPR3 JUP KDM3A LBP LCN2 LEF1 LEP LEPR LIPC LIPG LPIN1 LPIN2 LPIN3 LPL MAPT MBL2 MC3R MC4R MCHR1 MED12 MED13 MED13L MIF MMP9 MTOR MYC NAMPT NCOA1 NCOA3 NEIL1 NFE2L2 NMB NMU NMUR1 NMUR2 NNT NOS1 NOS2 NOS3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 NOX4 NPPA NPPB NPY1R NPY2R NPY5R NR1H3 NR3C1 NR3C2 NRF1 NUCB2 OPRM1 OXCT1 PCSK1 PCSK1N PDE3A PDP1 PDX1 PGF PGR PLAT PLAUR PLCB1 PLCB2 PLCB3 PLIN1 PLIN2 PLIN3 PLIN5 PLXNB1 PLXNB2 PLXNB3 PLXND1 PNLIP PNPLA2 PNPLA3 POMC PON2 PPARA PPARG PPARGC1A PPARGC1B PRKAA1 PRKAA2 PRKG1 PRL PRLHR PSMC3 PTPRF PUM1 PUM2 RAB7A RARRES2 RB1 RBP4 RELA REN RHOA RPS6KB1 SCP2 SDC1 SDC3 SDK1 SDK2 SEC16A SELP SERPINA12 SERPINF1 SFTPA1 SFTPA2 SFTPB SGPL1 SIRT1 SIRT3 SIRT6 SLC10A1 SLC15A1 SLC15A2 SLC2A1 SLC6A14 SLC6A3 SLC9A3 SNAP25 SOCS3 SORBS1 SPHK1 SPHK2 SRD5A1 SREBF2 STAT1 STAT3 STAT4 STIM1 STIM2 STK4 TBC1D5 TCF12 TCF3 TCF4 TF TFAM TGFB1 THADA THBD THBS1 TIMP1 TLR4 TNF TNFRSF1A TSC1 TUB TYK2 UCP2 UCP3 VWF WDTC1 WNT10B WNT1 ZFHX2 ZFHX3 ZFHX4	10013 10062 10135 10226 1027 10316 10580 1075 10874 10891 11095 11132 11254 11255 120227 123 123099 1232 1268 1277 1281 1282 1312 133 133522 134 1361 1363 1373 1374 1393 1394 145264 1499 154 155 1555 1571 1594 1634 1636 1645 1646 1672 177 1812 1813 1815 183 19 1906 196385 197 208 2099 2115 2147 2155 216 217 2180 219 221935 2260 2266 22852 23038 2309 23129 23175 23236 23369 23389 23410 23411 23530 23654 239 24147 2475 253559 2539 2559 2587 2597 26003 26354 2645 2673 268 2693 2696 27344 2740 2745 2752 2778 2798 2834 2835 2847 2876 2878 2908 2946 2984 3033 3077 3082 3091 3098 3099 3157 32 3240 3250 3290 3291 3293 3295 3304 335 3351 3356 3358 336 338 3383 344 345 3458 347 348 3480 3485 3486 3489 351 353500 3557 3562 3569 3570 3586 3600 3636 3651 3667 367 3684 3692 3700 3708 3709 3710 3728 38 387 3929 3934 3952 3953 3990 3992 4023 4137 4153 4159 4160 4282 4306 4318 434 440503 4609 463 4780 4828 4842 4843 4846 4851 4853 4854 4855 4878 4879 4886 4887 4889 4899 4925 496 4988 5019 50507 506 509 51 51083 51144 51176 5122 5139 51548 5167 51738 5176 5228 5241 5327 5329 5330 5331 5346 5364 5365 5406 5443 5445 54549 5465 5468 54704 54798 5562 5563 55818 5592 5617 563 56623 567 56848 56923 56999 5702 57104 572 57620 57678 5792 583 5919 5925 5950 5970 5972 6198 627 6342 6347 6352 6354 6382 63892 6403 64240 64241 6439 64900 6513 653 6531 653509 654 655 6550 6554 656 6564 6565 65985 6616 6715 6721 6772 6774 6775 6786 6789 6925 6929 6938 7018 7019 7040 7056 7057 7076 7099 7124 7132 718 7248 7275 728 729238 7297 7351 7352 7450 7471 7480 7840 7879 79068 79585 79633 79661 79776 80070 80339 8202 821 825 83854 85446 8560 8639 8642 8648 8694 8772 8854 886 8877 8879 9021 9370 9388 948 9507 958 959 9663 9672 9698 9759 9779 9919 9968 9969	Homo sapiens (human)	Alliance of Genome Resources
DOID:10763	hypertension Aliases: HTN hyperpiesia vascular hypertensive disorder	ABAT ABCC8 ABCC9 ABO ACE2 ACE ACSM3 ACTC1 ADAMTS16 ADCY5 ADD1 ADD2 ADD3 ADM ADORA1 ADORA2A ADRA1A ADRA2A ADRB1 ADRB2 ADRB3 AGER AGT AGTR1 AGTR2 AHR AKT1 AKT2 ALDH2 ALOX12 ALOX5 ANGPT1 ANXA1 APOA1 APOE APP AQP1 AQP2 AQP4 AR ARNT ATF2 ATP1A1 ATP1A2 ATP2A3 ATP5F1A ATP6AP2 AVP AVPR1A AVPR2 B2M BAD BAX BCHE BDKRB1 BDKRB2 BMP2 BRCA1 C3 CACNB2 CASP9 CAST CAT CCL28 CCL2 CCL5 CCR5 CD14 CD36 CD82 CHGA CHI3L1 CHST12 CLCNKB CLOCK CLU CNR1 COL6A3 COMT CORIN CPS1 CREB1 CRHR1 CTSC CYBB CYP11A1 CYP11B1 CYP11B2 CYP19A1 CYP1A1 CYP1B1 CYP2C18 CYP2C9 CYP2J2 CYP2R1 CYP4A11 CYP4A22 CYP4F12 CYP4F2 CYP4F8 DBH DRD1 DRD2 DRD3 ECE1 EDN1 EDN2 EDNRA EDNRB EGFR EIF4G2 ENG ENO1 ENO2 ENTPD2 EP300 EPHX2 EPOR F11R F2R F3 F7 FADD FADS1 FBN1 FN1 FOS FTO GABBR1 GAL GCK GLCE GLP1R GNAI2 GNAI3 GNAS GPX1 GPX3 GRK3 GSK3B GSTM2 H2AX HAVCR1 HDAC6 HGF HIF1A HK2 HLA-DQA1 HP HPR HRH3 HSD11B1 HSD11B2 HSD17B4 HSD3B1 HSD3B2 HSPA8 HSPD1 HSPG2 HTR1B HTR2A ICAM1 IGF1R IGFBP2 IKBKB IL10 IL17A IL1RN IL6 IL6R IL6ST INPPL1 INS INVS ITGA9 ITGAV JUN KCNA3 KCNJ11 KCNMB1 KCNN4 KCNQ1 KDR KL KLK1 KLKB1 LDHA LEP LEPR LGALS3 LINC02210-CRHR1 LIPG LOX LPL LRP2 LTA MAS1 MIF MME MMP1 MMP2 MMP9 MOV10 MTOR MTR MYH7 MYO6 NFE2L2 NGF NGFR NOS1 NOS2 NOS3 NOX4 NPHP3 NPPA NPPB NPPC NPR1 NPR3 NPY1R NR2F2 NR3C1 OGG1 OLR1 OPA1 OXTR PAPPA PDGFB PDGFRA PDGFRB PGF PKM PLCD1 PLEKHA7 PON1 POSTN PPARA PPARG PRKCA PRKG1 PRLHR PTGDS PTGIS PTGS2 PTK2 PTPN1 PTPRC PTPRD PTPRJ RAMP2 RBP4 RELA REN RHOA RNPEP S1PR1 SERPINA1 SERPINE1 SERPINE2 SERPINF2 SLC12A2 SLC2A14 SLC2A1 SLC2A3 SLC4A4 SLC5A2 SLC6A19 SLC6A2 SLC6A3 SLC8A1 SLC9A3 SOD1 SOD2 SOD3 SQSTM1 SRC SRF STS TACR3 TBXAS1 TF TGFB1 TGFB3 THBD TIMP1 TJP2 TNF TNFRSF11B TRHR UCP2 UCP3 UGCG UTS2R VCAM1 VEGFA VWF WNK1 XRCC1 YWHAZ	10013 10060 10159 10266 104909134 10631 10699 1075 111 1113 1116 11255 11283 118 1188 119 1191 120 120227 1234 1268 1293 1312 133 134 135 1373 1385 1386 1394 144100 144195 148 150 153 1536 154 1543 1545 155 1559 1562 157 1573 1579 1583 1584 1585 1588 1621 1636 170690 177 18 1812 1813 1814 183 185 186 1889 1901 1906 1907 1909 1910 1956 196 1982 2022 2023 2026 2033 2053 2057 207 208 2149 2152 2155 217 2200 2335 2353 239 240 2475 2550 26035 2645 26762 27031 27130 2740 2771 2773 2778 28 2834 2837 284 284541 2876 2878 2908 2932 2946 301 3014 3082 3091 3099 3117 3240 3250 3283 3284 3290 3291 3295 3312 3329 3339 335 3351 3356 3383 340024 348 3480 3485 351 3551 3557 3569 3570 3572 358 3586 359 3605 361 3630 3636 367 3680 3685 3725 3732 3738 3767 3779 3783 3784 3791 3816 3818 387 3939 3952 3953 3958 3992 4015 4023 4036 4049 405 412 4142 4282 4311 4312 4313 4318 4343 4548 4625 4646 476 477 4780 4803 4804 4842 4843 4846 4878 4879 4880 4881 4883 4886 489 4968 4973 4976 498 4982 5021 50507 5054 5069 50848 51083 5155 5156 5159 5228 5265 5270 5315 5333 5345 5444 5465 5468 551 552 554 55501 5578 5592 56477 567 572 5730 5740 5743 5747 5770 5788 5789 5795 581 590 59272 5950 5970 5972 6051 623 624 6296 6347 6352 650 65125 6513 6515 6524 6530 6531 6546 6550 6558 66002 6647 6648 6649 6714 672 6722 6833 6870 6916 70 7018 7026 7040 7043 7056 7076 7124 718 7201 7351 7352 7357 7412 7422 7450 7515 7534 783 79068 831 842 847 8529 8671 8772 8878 929 9365 9388 9414 948 954 9575	Homo sapiens (human)	Alliance of Genome Resources
DOID:0080556	congenital disorder of glycosylation Id Aliases: congenital disorder of glycosylation 1d	alg3	100127746	Xenopus tropicalis (tropical clawed frog)	Alliance of Genome Resources
DOID:5212	congenital disorder of glycosylation Aliases: carbohydrate-deficient glycoprotein syndrome	alg1 alg3 b4galt1.2 b4galt1	100127746 100145518 549418 594994	Xenopus tropicalis (tropical clawed frog)	Alliance of Genome Resources
DOID:3312	bipolar disorder Aliases: Manic Bipolar Affective disorder Manic Depressive disorder Manic bipolar I disorder bipolar depression bipolar disorder manic phase manic depression manic disorder mixed bipolar disorder	akt1.S grin2a.L ncam1.L ncam1.S ngf.S	100127346 108709389 397761 397762 399170	Xenopus laevis (African clawed frog)	Alliance of Genome Resources
DOID:9976	heroin dependence	drd2.L gdnf.L grin2a.L ngf.S	100127346 108709389 378584 779087	Xenopus laevis (African clawed frog)	Alliance of Genome Resources
DOID:0050741	alcohol dependence Aliases: alcoholism	drd2.L gdnf.L grin2a.L htr1a.L ncam1.L ncam1.S ngf.S pomc.L pomc.S	100127346 108709389 373802 378584 378605 380532 397761 397762 779087	Xenopus laevis (African clawed frog)	Alliance of Genome Resources
DOID:5419	schizophrenia Aliases: schizophrenia-1	akt1.S b3gat2.L b3gat2.S cnr1.S drd2.L fzd3.L grin2a.L ncam1.L ncam1.S ngf.S	100127346 108709389 108716933 373759 378584 397761 397762 399170 399190 733177	Xenopus laevis (African clawed frog)	Alliance of Genome Resources
DOID:12858	Huntington's disease Aliases: HD Huntington disease Huntington's chorea	agtr1.L grin2a.L nog.L nog.S npy2r.S	100127346 108704141 373646 378693 398763	Xenopus laevis (African clawed frog)	Alliance of Genome Resources
DOID:11206	opioid abuse	grin1.L grin1.S grin2a.L	100127346 108699855 397953	Xenopus laevis (African clawed frog)	Alliance of Genome Resources
DOID:8725	vascular dementia Aliases: Multi Infarct Dementia multifocal dementia	grin1.L grin1.S grin2a.L igf1r.S pon2.L pon2.S	100127346 108699855 380341 397953 398022 432039	Xenopus laevis (African clawed frog)	Alliance of Genome Resources
DOID:10652	Alzheimer's disease Aliases: Alzheimer disease Alzheimers dementia	agtr1.L bace2.L bace2.S ctsd.S drd1.L drd2.L drd5.S eno1.S epha4.S epor.L fgfr1.L fgfr1.S gapdh.S gdnf.L grin1.L grin1.S grin2a.L hmgcr.L htr1a.L igf1r.S insr.L ldlr.L ldlr.S ntf3.L plcd1.L plcd1.S pon2.L pon2.S psen1.L psen2.S ttr.L	100127346 108699855 108705891 108710578 108718712 108719811 373644 378584 378605 380259 380298 380307 380341 397713 397750 397757 397782 397787 397953 398006 398022 398763 398806 399258 399298 399444 432039 443721 734211 779062 779087	Xenopus laevis (African clawed frog)	Alliance of Genome Resources

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