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GlyCosmos Diseases

List of diseases involving glycan related genes. The information of each database of Glyco-Disease Genes Database (GDGDB) and Alliance of Genome Resources is integrated into one list.

Source	Last Updated
Alliance of Genome Resources	October 9, 2024
Glyco-Disease Genes Database (GDGDB)	January 25, 2017

Displaying entries **15701 - 15725** of **15957** in total

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Disease ID	Disease Name	Gene Symbol ▼	Gene ID	Organism	Source
DOID:6000	congestive heart failure Aliases: CHF Cardiac Failure Congestive Congestive heart disease Weak heart	ACAN ACE2 ACE ADAM17 ADIPOQ ADM ADRA2C ADRB1 ADRB2 ADRB3 AGER AGT AGTR1 AGTR2 ALB ALOX12 ALOX15 AOC3 APOA1 APOE ARRB1 BAX CALR CASQ2 CAT CBL CCL2 CCN1 CCR2 CD40LG CHEK2 CHI3L1 CHRM4 CHRNA4 CORIN CREB1 CS CXCR4 CYP11B1 CYP1A2 DDR1 DNMT1 DYRK1A ECE1 EDN1 ENG EP300 EPO ERBB2 ERBB4 EYA4 EZH2 FADS1 FADS2 FAS FASLG FOS FOXC1 FOXO1 FOXP1 FOXP4 FTH1 FTO GNB1 GP6 GRK1 GRK3 GRP HIF1A HMGB1 HP HPR HSF1 HTR2A HTR2B IL10 IL17A IL6 IL6R INHBA KCNE1 KCNK2 LEPR LGALS3 LIF LTBP2 MAS1 MDH2 MED1 MME MMP13 MMP14 MMP1 MMP2 MMP3 MMP8 MMP9 MSTN MTOR MYH7 NCAM1 NFE2L2 NGFR NME2 NOS1 NOS3 NPPA NPPB NPTXR NR3C1 OGT OPA1 OPRK1 P2RX4 PARP1 PGF PHF6 PLA2G7 PLCD1 PLD2 POSTN PPARGC1A PPP1CC PRKCA PTGIS RAC1 RAMP2 RAPGEF3 RBM10 RBP4 REN RRAD RYR1 RYR2 SCN5A SCN8A SELP SIRT3 SLC22A5 SLC2A4 SLC6A4 SLC8A1 SLC9A1 SMC1A SOD2 SOX2 SRA1 SRF TIMP1 TNF TNFRSF11B TNFRSF1B TREM1 UCP2 UCP3 YY1	10011 10266 10411 10631 10699 10891 1116 11200 1132 1137 116113 133 1385 142 1431 152 153 154 1544 155 157 1584 1636 176 177 1786 183 185 1859 186 1889 1906 2022 2033 2056 2064 2066 2070 213 2146 2296 2308 23410 23467 2353 239 246 2475 2495 2660 27086 2782 2908 2922 3091 3146 3240 3250 3297 335 3356 3357 348 3491 355 356 3569 3570 3586 3605 3624 3753 3776 3953 3958 3976 3992 4053 408 4142 4191 4311 4312 4313 4314 4317 4318 4322 4323 4625 4684 4780 4804 4831 4842 4846 4878 4879 4976 4982 4986 5025 51206 5228 5333 5338 54210 5469 5501 5578 5740 581 5879 59272 5950 5972 6011 6236 6261 6262 6331 6334 6347 6403 6517 6532 6546 6548 6584 6648 6657 6722 6868 7076 7124 7133 729230 7351 7352 7528 780 7852 79068 7941 811 8241 8243 84295 845 847 8473 8639 867 9370 9415 959	Homo sapiens (human)	Alliance of Genome Resources
DOID:0080154	short chain acyl-CoA dehydrogenase deficiency	ACADS	35	Homo sapiens (human)	Alliance of Genome Resources
DOID:1574	alcohol use disorder Aliases: Ethanol abuse alcohol abuse	ACADS ACSS2 ACTL6A ADCY1 ADCYAP1R1 ADGRF3 ADH5 ADRA1A ADRA1B ADRA1D AKT1 AKT2 AKT3 ALDH2 ALYREF ANGPT1 ANGPT2 ANGPT4 ANGPTL3 ANGPTL4 ANGPTL6 ARID1A ARID2 ATF1 ATP1A1 ATP1A2 AUTS2 BDNF BRD7 CALB1 CAMK4 CAST CAT CDC5L CFL1 CHRNA1 CHRNA2 CHRNA3 CHRNA4 CHRNA6 CHRNB1 CHRNB2 CHRNB3 CHRND CHRNE CHRNG CIZ1 CLIC1 CLOCK CNR1 COMT CREB1 CREBBP CTSL CTSV CYP2E1 DBH DDX17 DRD1 DRD2 DRD3 DRD4 DRD5 EGFR EP300 EPS8 EPS8L2 ERBB2 ERBB3 ERBB4 FADS1 FADS2 FBRSL1 FMR1 FOS FOSB GABBR2 GABRA2 GABRB3 GAD1 GAD2 GDNF GHRHR GIPR GLP1R GPR21 GPR52 GRIA1 GRIN1 GRIN2B GRK1 GRK7 GSTO1 GSTO2 HDAC2 HOMER2 HTR1A HTR1B HTR2A HTR2C HTR3B HTR7 IGF2 IL10 JMJD1C KCNMA1 KCNU1 KDM3A KDM3B KDM4C KDM5B KDM6A KDM6B MADD MAOA MKI67 MLXIP MLXIPL MMP2 MMP9 NCAM1 NGF NOTCH1 NOTCH2 NOTCH3 NPY5R NR3C2 NRG1 NTF3 NTRK2 OPRD1 OPRK1 OPRL1 OPRM1 PBRM1 PCSK2 PDPK1 PIK3CB PIK3CD POMC PPP1R3B PPP1R3C PRKACB PRKCA PRKCH PRLHR PSD RAB3B RAC1 RAC2 RAC3 RASA1 RBPJ RPL18A RYR1 RYR2 RYR3 SHMT1 SHMT2 SIRT1 SLC32A1 SLC6A4 SMARCA2 SMARCA4 SMARCC1 SMARCC2 SMARCD1 SMARCD2 SOD1 SOX2 SREBF1 SREBF2 SRRM2 SSH2 ST6GAL1 STXBP1 STXBP2 SYP TIMELESS TPH1 UNC13A UNC13B UNC79 UTY VIPR1 VIPR2	10000 10189 10497 10521 107 1072 10765 1134 1135 1136 1137 1140 1141 1142 1144 1145 1146 117 1192 119391 1268 128 1312 131890 1385 1387 140679 146 147 148 1514 1515 1571 157855 1621 165082 1812 1813 1814 1815 1816 1956 196528 2033 2059 2064 2065 2066 207 208 217 221037 22877 23025 23081 23135 2332 23411 23524 2353 2354 2555 2562 2571 2572 25792 26053 2668 2692 2696 27329 2740 2834 284 2844 285 2890 2902 2904 29117 3066 3084 3350 3351 3356 3358 3363 3481 35 3516 3586 3778 3992 4128 4288 4306 4313 4318 466 4684 476 477 4803 4851 4853 4854 4889 4908 4915 4985 4986 4987 4988 51085 51129 5126 51378 5170 51780 5291 5293 5443 5507 55193 5567 5578 55818 5583 55902 5662 57578 57666 5865 5879 5880 5881 5921 6011 6142 6261 6262 6263 627 6470 6472 64787 6480 6532 6595 6597 6599 6601 6602 6603 6647 6657 6720 6721 6812 6813 6855 7166 7403 7404 7433 7434 793 79660 814 8289 831 83854 847 85464 8567 86 8914 8973 9177 9293 9415 9446 9455 9568 9575 988	Homo sapiens (human)	Alliance of Genome Resources
DOID:0080153	medium chain acyl-CoA dehydrogenase deficiency	ACADM	34	Homo sapiens (human)	Alliance of Genome Resources
DOID:0080155	very long chain acyl-CoA dehydrogenase deficiency Aliases: VLCAD deficiency	ACADL ACADVL	33 37	Homo sapiens (human)	Alliance of Genome Resources
DOID:0112072	nuclear type mitochondrial complex I deficiency 20 Aliases: ACAD9 deficiency Acyl-CoA dehydrogenase 9 deficiency MC1DN20 mitochondrial complex 1 deficiency due to ACAD9 deficiency	ACAD9 ACADL	28976 33	Homo sapiens (human)	Alliance of Genome Resources
DOID:0080547	metabolic dysfunction-associated steatohepatitis Aliases: MASH NASH non-alcoholic steatohepatitis nonalcoholic steatohepatitis	ACACA ACER3 ADRA2A APOA1 AZGP1 CCL2 CCL5 CD68 CLDN1 COL1A1 CPT1A CYP27A1 CYP7A1 GPBAR1 HSPA5 HTR2B ICAM1 IL10 IL6 IRF5 KRT18 LEPR MC4R MLXIPL NFE2L2 NFKB1 NOX4 PCK1 PDGFRB RIPK3 SCD SERPINF1 SMAD4 SOD1 SOD2 SPHK2 SREBF1 TIMP1 TNF	11035 1277 1374 150 151306 1581 1593 31 3309 335 3357 3383 3569 3586 3663 3875 3953 4089 4160 4780 4790 50507 5105 51085 5159 5176 55331 563 56848 6319 6347 6352 6647 6648 6720 7076 7124 9076 968	Homo sapiens (human)	Alliance of Genome Resources
DOID:0080000	muscular disease	ACACA ACACB CLU CPT2 FASN HMGCR ITGA7 LPL	1191 1376 2194 31 3156 32 3679 4023	Homo sapiens (human)	Alliance of Genome Resources
DOID:1496	echinococcosis Aliases: Echinococcosis of liver echinococcal disease hepatic echinococcosis hydatid disease hydatidosis liver echinococcus pulmonary echinococcosis	ABO	28	Homo sapiens (human)	Alliance of Genome Resources
DOID:13406	pulmonary sarcoidosis Aliases: lung Sarcoidosis	ABO BDNF C3 CCL5 CCR5 CCR7 CFTR CHI3L1 CXCR3 DEFB1 EGR1 HLA-DRB1 IL15 IL18R1 IL1RN LTA MUC1 NGF NOD2 NOS2 NR3C1 NTF3 NTRK1 SFTPA1 TGFB1 TLR2 TNC TNF TNFRSF1B	1080 1116 1234 1236 1672 1958 28 2833 2908 3123 3371 3557 3600 4049 4582 4803 4843 4908 4914 627 6352 64127 653509 7040 7097 7124 7133 718 8809	Homo sapiens (human)	Alliance of Genome Resources
DOID:4948	gallbladder carcinoma Aliases: cancer of the gallbladder carcinoma gallbladder carcinoma of gallbladder	ABO ANTXR1 CFL1 CLPTM1L GPX3 IL10 PTCH1 RAC1 TERT TGFA TJP1 TYMP UBR5	1072 1890 28 2878 3586 51366 5727 5879 7015 7039 7082 81037 84168	Homo sapiens (human)	Alliance of Genome Resources
DOID:2237	hepatitis Aliases: acute and subacute liver necrosis acute hepatitis acute/subac. necrosis of liver animal hepatitis chronic hepatitis chronic persistent hepatitis	ABO AFP ATP7B F5 GOLM1 IFNG LIPC NOS2 OGG1 PDCD1 SPP1 TF	174 2153 28 3458 3990 4843 4968 51280 5133 540 6696 7018	Homo sapiens (human)	Alliance of Genome Resources
DOID:0081267	graft-versus-host disease Aliases: GvHD graft versus host disease	ABO ADIPOQ APOA4 CTLA4 F3 FAS FASLG FCGR3A HGF HLA-A HLA-B HLA-C HLA-DPB1 HLA-E HLA-F HLA-G HSPA1A HSPA1B HSPA8 IFNG IL10 IL10RB IL1A IL1RN IL2 JAK3 MKI67 NOD2 PDGFB SELL TFPI TP53 VEGFA	1493 2152 2214 28 3082 3105 3106 3107 3115 3133 3134 3135 3303 3304 3312 337 3458 355 3552 3557 3558 356 3586 3588 3718 4288 5155 6402 64127 7035 7157 7422 9370	Homo sapiens (human)	Alliance of Genome Resources
DOID:14067	Plasmodium falciparum malaria Aliases: Malaria fever, subtertian falciparum malaria malignant tertian fever	ABO ADAMTS13 CAST CYP2C19 FCGR2A G6PD HLA-DQB1 HP IL13 MBL2 TNF	11093 1557 2212 2539 28 3119 3240 3596 4153 7124 831	Homo sapiens (human)	Alliance of Genome Resources
DOID:2945	severe acute respiratory syndrome Aliases: SARS SARS-CoV infection	ABO ACE2 ANPEP BPI C5AR1 CASP9 CCL2 CCL5 CD14 CD4 CD68 CD9 CEACAM8 CLCF1 CLEC4M FGF7 FSHB HLA-B HLA-DRA HLA-DRB1 HP IFNG IL10 IL1R1 IL6 ITGA2B LHB MSR1 PECAM1 PLAT POMC PRL RAB31 SERPINA3 STAT1 TGFB1 THBD TLR2 TNF TSHB	10332 1088 11031 12 2252 23529 2488 28 290 3106 3122 3123 3240 3458 3554 3569 3586 3674 3972 4481 5175 5327 5443 5617 59272 6347 6352 671 6772 7040 7056 7097 7124 7252 728 842 920 928 929 968	Homo sapiens (human)	Alliance of Genome Resources
DOID:552	pneumonia Aliases: acute pneumonia	ABO ACE ADRB2 ALB C3 C5 CCL11 CCL7 CCR7 CD14 CD163 CYP1A1 CYP2E1 DEFB1 EDN1 FCGR3A GRP ICAM1 IKBKB IL10 IL13 IL13RA2 IL1A IL1RN IL6 IRF5 ITGA4 ITGB2 MBL2 MIF MUC1 MUC2 REG3G SERPINE1 SFTPA1 SFTPB SFTPD SLC11A2 SOD3 TGFB1 TNC TNFRSF1B	1236 130120 154 1543 1571 1636 1672 1906 213 2214 28 2922 3371 3383 3551 3552 3557 3569 3586 3596 3598 3663 3676 3689 4153 4282 4582 4583 4891 5054 6354 6356 6439 6441 653509 6649 7040 7133 718 727 929 9332	Homo sapiens (human)	Alliance of Genome Resources
DOID:1240	leukemia	ABO ACE ACSL6 AKR1C3 ALB ASH1L ATM BCR CD28 DAXX DOT1L FADD GPX1 HRAS IRF4 KRAS MEIS1 NRAS PDGFRA PTPN11 PTPN6 TFPI TP53	1616 1636 213 23305 28 2876 3265 3662 3845 4211 472 4893 5156 55870 5777 5781 613 7035 7157 84444 8644 8772 940	Homo sapiens (human)	Alliance of Genome Resources
DOID:4914	esophagus adenocarcinoma Aliases: Oesophageal adenocarcinoma	ABL1 ARID1A CDC5L CTSB CYP19A1 CYP24A1 FAS FOXA1 FOXP1 GHRL GPX3 GRB7 KDR MMP12 MMP14 MMP1 MMP3 MMP9 NOS3 PTGS1 PTGS2 SMO SOD2 TNFRSF10A	1508 1588 1591 25 27086 2878 2886 3169 355 3791 4312 4314 4318 4321 4323 4846 51738 5742 5743 6608 6648 8289 8797 988	Homo sapiens (human)	Alliance of Genome Resources
DOID:0080630	B-lymphoblastic leukemia/lymphoma Aliases: B lymphoblastic leukemia/lymphoma B-ALL precursor B lymphoblastic lymphoma/leukemia	ABL1 AKR1C3 BRD2 CYP3A5 F13A1 F3 FLT3 IKZF1 STAT5A TFPI TNFSF13 TP53	10320 1577 2152 2162 2322 25 6046 6776 7035 7157 8644 8741	Homo sapiens (human)	Alliance of Genome Resources
DOID:0050866	oral squamous cell carcinoma Aliases: mouth squamous cell carcinoma	ABL1 AGAP2 ARID2 ARPC1B ATM AZGP1 BIRC2 BRINP2 BST2 CALR CBX2 CCL2 CCR2 CDC73 CDH1 CHAF1B CLPTM1L CTNND1 CYP1A1 CYP24A1 CYP2E1 DAXX DDR1 DDR2 DOCK6 EGFR ERBB2 ERBB4 EZH2 FAT1 FGFR3 FGFR4 FLT3 FOSL2 GAPDH GSK3B H2AX HP IL10 IL13RA2 IL2 IL6 JUN JUNB KMT2D MET PLAU PLCG1 PRDX2 PTEN PTGIS PTPN13 RELA SERPINE1 SKP2 SLC7A5 TERT TET2 TNF TP53 TTR WNT11	10095 116986 1500 1543 1571 1591 1616 1956 196528 2064 2066 2146 2195 2261 2264 2322 2355 25 2597 2932 3014 3240 329 3558 3569 3586 3598 3725 3726 4233 472 4921 5054 5328 5335 54790 563 5728 5740 57572 57795 5783 5970 6347 6502 684 7001 7015 7124 7157 7276 729230 7481 780 79577 8085 81037 811 8140 8208 84733 999	Homo sapiens (human)	Alliance of Genome Resources
DOID:9256	colorectal cancer	ABL1 ADAM10 ADAM28 ADGRB1 ADM AFF4 AKT1 AKT2 ALX4 ANTXR1 APC2 APC APOC3 ARID1A ARID2 ATF7 ATM AZGP1 BAMBI BAX BCOR BIRC2 BRCA1 BRCA2 BTK BUB1B CALR CASP9 CBL CDC73 CES1 CHD4 CHEK2 CTNNB1 CTNNBL1 CXCR4 CYP24A1 CYP2E1 DCC DDR1 DDR2 DDX3X DICER1 DLC1 DPYD DSN1 EEF1E1 EEF2 EGFR EIF5A EP300 ERBB4 ERCC6 EZH2 F7 FASN FAT1 FGFR3 FGR FLCN FOSL2 FOXA1 GAD1 GALNT12 GCLC GLI1 GPX1 GPX2 GRIN2A GRP HCK HDAC1 HDAC3 HDAC7 HFE HIF1A HILPDA HK1 HLA-DQB1 HNF1A HNRNPK HNRNPU HRAS HSPA8 IKZF1 IL6 IRS4 ITPKC JAK1 KDM3B KDM6A KDR KIF18A KRAS L1CAM LATS2 LIF LOX LRP1B MAP2K4 MAP4K4 MAPK9 MKI67 MLH1 MMP2 MMP9 MSH2 MYD88 NFE2L2 NOTCH1 NOTCH2 NOTCH3 NRAS NTRK3 NUF2 OSBP PBRM1 PDGFRL PIK3CA PIK3CB PIK3CD PLA2G2A PLCG1 POLD1 POLE PRDM1 PRDX2 PTEN PTPN12 PTPN13 PTPRJ PTPRT RAB1A RAC1 RAMP2 RAMP3 RBM10 RHOA RICTOR RNF43 SEPTIN9 SERPINA1 SERPINF1 SETD2 SHH SLC7A5 SMARCC1 SMC2 SMO SNAI1 SPOP SRC STAT3 STIM1 TBX3 TCF3 TET2 TGFB1 TGFB2 TGFB3 TGFBR1 THBS1 TLR2 TNFAIP3 TP53 TTR VEGFA XIAP XPO1 XPO5 XRCC1 YAP1 YTHDF1 ZFHX3	102 10266 10268 10297 10320 10395 10413 10592 1066 10801 10863 11016 1108 11122 11200 133 1499 1571 1591 1630 1654 1806 1938 1956 196528 1984 201163 2033 2066 207 2074 208 2146 2155 2194 2195 2261 2268 23405 2355 25 253260 2571 25805 26524 27125 2729 2735 2876 2877 2903 29072 2922 29923 3055 3065 3077 3091 3098 3119 3169 3190 3192 324 3265 329 331 3312 345 3569 3716 3791 3845 387 3897 3976 4015 4288 4292 4313 4318 4436 4615 463 472 4780 4851 4853 4854 4893 4916 4921 5007 51564 5157 5176 51780 5265 5290 5291 5293 5320 5335 53353 5424 5426 54790 54880 54894 54915 55193 5601 56259 563 5728 575 57510 5782 5783 5795 581 5861 5879 60529 639 6416 6469 6599 6608 6615 6714 672 675 6774 6786 6926 6927 6929 695 7001 701 7040 7042 7043 7046 7057 7097 7128 7157 7276 7403 7422 7514 7515 780 7852 79577 79695 79980 80271 811 8140 81930 8241 8289 83540 8405 84168 842 8471 867 8841 9448 9521	Homo sapiens (human)	Alliance of Genome Resources
DOID:5199	ureteral obstruction	ABL1 ACE ADAMTS1 ADCY6 ADM AKT1 AVPR2 B2M CASP7 CASP9 CAT CCL11 CCN2 CFL1 COL1A1 COL1A2 CYP2J2 DRD1 EDN1 FN1 GFER HSD11B2 HSPA5 ICAM1 IFNG IL1RN IRF5 KEAP1 LUM MTOR NPPA PAK2 PARP1 PDGFB RELB SERPINE1 SKIL TNF TNFRSF1A TNFRSF1B	1072 112 1277 1278 133 142 1490 1573 1636 1812 1906 207 2335 2475 25 2671 3291 3309 3383 3458 3557 3663 4060 4878 5054 5062 5155 554 567 5971 6356 6498 7124 7132 7133 840 842 847 9510 9817	Homo sapiens (human)	Alliance of Genome Resources
DOID:10534	stomach cancer Aliases: gastric cancer gastric neoplasm	ABL1 ACE ACVR1B ADAR ADGRB1 ADM AKR1B1 ANXA1 APC ARID1A ARPC1B ASPM ATM ATP4B BAMBI BAX BCOR BGN BRCA1 BST2 CALR CASP9 CCL5 CCN3 CD1D CD274 CD8A CDK12 CES1 CHRNA3 COL6A3 CSF1R CTNNB1 CUX1 CXCR4 CYP1A1 CYP2E1 DAXX DDR2 DICER1 DOCK6 EEF1E1 EEF2 EFNB1 EFNB2 EPHB1 ERBB2 ERCC5 ERCC6 EZH2 FGFR2 FGFR4 FOXA1 FOXM1 FUBP1 FUT11 GDA GLDC GPX1 GPX3 GSE1 HDAC2 HLA-DQA1 IDH2 IGFBP3 IL10 IL1RN IL5 IL6 IL6R IL6ST IL7R JAK1 KDM6A KDR KIF18A KMT2C KMT2D KRAS LRP1B LRRN1 MAP3K1 MAP4K4 MKI67 MMP9 MUTYH NBEA NCOA2 NFKB1 NTRK3 NUF2 PARP1 PCNA PDCD1 PIK3CA PTCH1 PTEN PTPN11 RAC1 RGN RICTOR RNF43 RUNX1 RUNX3 SETD2 SGCE SHH SLC7A5 SMO SOD2 SPOP SRC STAT3 STIM1 TBX3 TEP1 TERT TET2 TFF1 TMEM260 TNFRSF11A TP53 TTR UBR5 XPO1 XRCC1	10095 103 10499 1066 1136 1293 133 142 1436 1499 1523 1543 1571 1616 1636 170384 1938 1947 1948 2047 2064 2073 2074 2146 2263 2264 2305 231 23199 23405 25 253260 25805 259266 26960 2731 2876 2878 29072 29126 301 3066 3117 3169 324 3418 3486 3557 3567 3569 3570 3572 3575 3586 3716 3791 3845 4214 4288 4318 4595 472 4790 4856 4916 4921 496 5111 5133 51366 51755 5290 53353 54790 54880 54894 54916 5727 5728 575 57572 57633 5781 581 58508 5879 633 6352 6469 6608 6648 6714 672 6774 6786 684 6926 7011 7015 7031 7157 7276 7403 7514 7515 7852 8085 811 8140 81930 8289 83540 8405 842 861 864 8792 8880 8910 91 9104 912 925 9448 9521 9615	Homo sapiens (human)	Alliance of Genome Resources
DOID:0080181	PHARC syndrome Aliases: polyneyropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract	ABHD12	26090	Homo sapiens (human)	Alliance of Genome Resources
DOID:0090019	sitosterolemia Aliases: phytosterolemia	ABCG5 ABCG8	64240 64241	Homo sapiens (human)	Alliance of Genome Resources

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